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Gender-based harassment in Swedish workplaces and alcohol-related morbidity and mortality: A prospective cohort study. 瑞典工作场所的性别骚扰与酒精相关的发病率和死亡率:一项前瞻性队列研究。
IF 6.3 2区 医学 Q1 Medicine Pub Date : 2023-09-01 Epub Date: 2023-06-25 DOI: 10.5271/sjweh.4101
Katrina J Blindow, Emelie Thern, Julio C Hernando-Rodriguez, Anna Nyberg, Linda L Magnusson Hanson

Objective: The study investigated experiences of different types of work-related gender-based harassment (GBH), specifically sexual and gender harassment, as risk factors for alcohol-related morbidity and mortality (ARMM).

Methods: Information about experiences of (i) sexual harassment (SH-I) and (ii) gender harassment (GH-I) from inside the organization and (iii) sexual harassment from a person external to the organization (SH-E) were obtained from the Swedish Work Environment Survey 1995-2013, a biannual cross-sectional survey, administered to a representative sample of the Swedish working population. The survey responses from 86 033 individuals were connected to multiple registers containing information about alcohol-related diagnoses, treatment, or cause of death. Cox proportional hazard models were fitted to assess hazard ratios (HR) of incident ARMM during a mean follow-up of eight (SH-I and GH-I) and ten (SH-E) years.

Results: A higher prospective risk estimate of ARMM was found among participants who reported experiences of SH-E [HR 2.01, 95% confidence interval (CI) 1.61-2.52], GH-I (HR 1.33, CI 1.03-1.70), or SH-I (HR 2.37, CI 1.42-3.00). Additional analyses, distinguishing one-time from reoccurring harassment experiences, indicated a dose-response relationship for all three harassment types. Gender did not modify the associations. Under the assumption of causality, 9.3% (95% CI 5.4-13.1) of the risk of ARMM among Swedish women and 2.1% (95% CI 0.6-3.6) among Swedish men would be attributable to any of the three types of GBH included in this study.

Conclusions: Experiences of GBH in the work context may be a highly relevant factor in the etiology of ARMM.

目的:本研究调查了与工作有关的不同类型的性别骚扰(GBH),特别是性骚扰和性别骚扰,作为酒精相关发病率和死亡率(ARMM)的风险因素:本研究调查了与工作有关的不同类型的性别骚扰(GBH)经历,特别是性骚扰和性别骚扰,作为与酒精有关的发病率和死亡率(ARMM)的风险因素:有关(i)来自组织内部的性骚扰(SH-I)和(ii)来自组织外部的性别骚扰(GH-I)以及(iii)来自组织外部的性骚扰(SH-E)经历的信息来自 1995-2013 年瑞典工作环境调查,这是一项两年一次的横断面调查,对瑞典工作人口进行了代表性抽样调查。来自 86 033 名个人的调查回复与多个登记簿相连,登记簿中包含与酒精相关的诊断、治疗或死因信息。结果发现,在平均八年(SH-I 和 GH-I)和十年(SH-E)的随访期间,Cox 比例危险模型可评估发生 ARMM 的危险比 (HR):结果发现,报告有 SH-E [HR 2.01,95% 置信区间 (CI)1.61-2.52]、GH-I (HR 1.33,CI 1.03-1.70)或 SH-I (HR 2.37,CI 1.42-3.00)经历的参与者中,ARMM 的前瞻性风险估计值较高。对一次性骚扰经历和重复性骚扰经历进行的其他分析表明,所有三种骚扰类型都存在剂量-反应关系。性别并没有改变这种关系。根据因果关系假设,瑞典女性中 9.3% (95% CI 5.4-13.1)的 ARMM 风险和瑞典男性中 2.1% (95% CI 0.6-3.6)的 ARMM 风险可归因于本研究中包含的三种 GBH 中的任何一种:结论:工作环境中的GBH经历可能是ARMM病因中的一个高度相关因素。
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引用次数: 0
Burden of idiopathic inflammatory rheumatic diseases in occupational healthcare: increased absenteeism and healthcare resource utilization. 特发性炎症性风湿病在职业保健中的负担:缺勤率和保健资源利用率增加。
IF 6.3 2区 医学 Q1 Medicine Pub Date : 2023-07-01 Epub Date: 2023-04-24 DOI: 10.5271/sjweh.4095
Liisa Ukkola-Vuoti, Antti Karlsson, Samuli Tuominen, Mariann I Lassenius, Jaakko Aaltonen, Martta Ranta, Mikko Kosunen, Mari Renlund, Anne Lehtonen, Kari Puolakka

Objectives: Patients with idiopathic inflammatory rheumatic diseases (IIRD) often have decreased working capacity resulting in indirect costs. However, data on patients' short-term sick leave has been limited. This retrospective cohort study evaluated the number and length of sick leave, including short-term leave, and occupational healthcare resource utilization (HCRU) of the working-aged patients with IIRD compared to controls.

Methods: The data on sick leave and occupational HCRU were gathered from the electronic medical records of the largest occupational healthcare provider in Finland from January 2012 to December 2019. Employed patients with an IIRD (including rheumatoid arthritis, spondyloarthritis, psoriatic and enteropathic arthritis, juvenile arthritis, and reactive arthritis) with at least a 12-months follow-up were identified and compared to age-, sex-, and follow-up matched controls without IIRD.

Results: Altogether 5405 patients with IIRD were identified and compared with an equal number of controls. The patients incurred approximately 2.5 times more sick leave than controls: 21.7 versus 8.5 days per patient year, respectively. Short-term sick leave was common: 83% of sickness absence periods of the patients lasted 1-9 days and represented 30% of the total absenteeism. Loss of productivity due to lost workdays was on average €4572 (95% confidence interval €4352-4804) per patient year. Occupational HCRU was approximately 1.8 times higher among IIRD patients than controls.

Conclusions: Workers with an IIRD incur considerably more sick leave and use more occupational healthcare services than controls. Short sick leave not registered in national insurance registers constitute a significant portion of days off work among patients with IIRD.

目的:特发性炎症性风湿病(IIRD)患者的工作能力通常会下降,从而导致间接成本的增加。然而,有关患者短期病假的数据却很有限。这项回顾性队列研究评估了与对照组相比,特发性炎症性风湿病工作年龄段患者的病假(包括短期病假)次数和时长以及职业医疗资源利用率(HCRU):2012年1月至2019年12月期间,病假和职业保健资源利用率的数据来自芬兰最大的职业保健提供商的电子病历。研究人员确定了至少随访12个月的IIRD(包括类风湿性关节炎、脊柱关节炎、银屑病和肠病关节炎、幼年关节炎和反应性关节炎)患者,并将其与无IIRD的年龄、性别和随访匹配对照组进行了比较:结果:共发现了 5405 名 IIRD 患者,并与同等数量的对照组进行了比较。患者的病假是对照组的约 2.5 倍:分别为每年 21.7 天和 8.5 天。短期病假很常见:83%的患者病假持续时间为 1-9 天,占总缺勤时间的 30%。因工作日损失而造成的生产率损失平均为每患者年 4572 欧元(95% 置信区间为 4352-4804 欧元)。IIRD患者的职业性HCRU是对照组的约1.8倍:结论:与对照组相比,患有 IIRD 的工人病假更多,使用的职业医疗服务也更多。未在国家保险登记册中登记的短期病假占 IIRD 患者请假天数的很大一部分。
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引用次数: 0
Association of persistent pain with the incidence of chronic conditions following a disabling work-related injury. 工伤致残后持续疼痛与慢性病发病率的关系。
IF 6.3 2区 医学 Q1 Medicine Pub Date : 2023-07-01 Epub Date: 2023-04-30 DOI: 10.5271/sjweh.4096
Kathleen G Dobson, Cameron A Mustard, Nancy Carnide, Andrea D Furlan, Peter M Smith

Objectives: In a cohort of workers disabled by a work-related injury or illness, this study aimed to: (i) compare pre-injury prevalence estimates for common chronic conditions to chronic condition prevalence in a representative sample of working adults; (ii) calculate the incidence of chronic conditions post-injury; and (iii) estimate the association between persistent pain symptoms and the incidence of common chronic conditions.

Methods: Eighteen months post-injury, 1832 workers disabled by a work-related injury or illness in Ontario, Canada, completed an interviewer-administered survey. Participants reported pre- and post-injury prevalence of seven physician-diagnosed chronic conditions, and demographic, employment, and health characteristics. Pre-injury prevalence estimates were compared to estimates from a representative sample of workers. Multivariable logistic regression was used to examine the association of persistent pain with post-injury chronic condition incidence.

Results: Age-standardized pre-injury prevalence rates for diabetes, hypertension, arthritis, and back problems were similar to prevalence rates observed among working adults in Ontario, while prevalence rates for mood disorder, asthma and migraine were moderately elevated. Post-injury prevalence rates of mood disorder, migraine, hypertension, arthritis, and back problems were elevated substantially in this cohort. High persistent pain symptoms were strongly associated with the 18-month incidence of these conditions.

Conclusions: The incidence of five chronic conditions over an 18-month follow-up period post injury was substantial. Persistent pain at 18 months was associated with this elevated incidence, with population attributable fraction estimates suggesting that 37-39% of incident conditions may be attributed to exposure to high levels of persistent pain.

研究目的在因工伤或疾病致残的工人群体中,本研究旨在(i)比较受伤前常见慢性病的患病率估计值与具有代表性的工作成年人样本中的慢性病患病率;(ii)计算受伤后慢性病的发病率;(iii)估计持续疼痛症状与常见慢性病发病率之间的关联:方法:加拿大安大略省的 1832 名因工伤或疾病致残的工人在受伤后 18 个月内完成了一项由访问者主持的调查。参与者报告了受伤前和受伤后七种经医生诊断的慢性病的患病率,以及人口、就业和健康特征。受伤前的患病率估计值与具有代表性的工人样本估计值进行了比较。采用多变量逻辑回归法研究了持续性疼痛与受伤后慢性病发病率之间的关系:结果:受伤前糖尿病、高血压、关节炎和背部问题的年龄标准化患病率与在安大略省工作的成年人中观察到的患病率相似,而情绪障碍、哮喘和偏头痛的患病率则略有上升。在这组人群中,情绪障碍、偏头痛、高血压、关节炎和背部问题的受伤后患病率大幅上升。高持续性疼痛症状与这些疾病的 18 个月发病率密切相关:结论:在受伤后 18 个月的随访期间,五种慢性疾病的发病率非常高。结论:在受伤后 18 个月的随访期间,五种慢性疾病的发病率非常高,18 个月时的持续疼痛与发病率的升高有关,人口可归因分数估计表明,37%-39% 的发病情况可能是由于暴露于高水平的持续疼痛所致。
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引用次数: 1
How effective are organizational-level interventions in improving the psychosocial work environment, health, and retention of workers? A systematic overview of systematic reviews. 组织层面的干预措施在改善工人的社会心理工作环境、健康和留任方面的效果如何?系统综述。
IF 6.3 2区 医学 Q1 Medicine Pub Date : 2023-07-01 Epub Date: 2023-05-09 DOI: 10.5271/sjweh.4097
Birgit Aust, Jeppe Lykke Møller, Mads Nordentoft, Karen Bo Frydendall, Elizabeth Bengtsen, Andreas Brøgger Jensen, Anne Helene Garde, Michiel Kompier, Norbert Semmer, Reiner Rugulies, Sofie Østergaard Jaspers

Objective: This study aimed to systematically review the effectiveness of organizational-level interventions in improving the psychosocial work environment and workers' health and retention.

Methods: We conducted an overview of systematic reviews on organizational-level interventions published between 2000 and 2020. We systematically searched academic databases, screened reference lists, and contacted experts, yielding 27 736 records. Of the 76 eligible reviews, 24 of weak quality were excluded, yielding 52 reviews of moderate (N=32) or strong (N=20) quality, covering 957 primary studies. We assessed quality of evidence based on quality of review, consistency of results, and proportion of controlled studies.

Results: Of the 52 reviews, 30 studied a specific intervention approach and 22 specific outcomes. Regarding intervention approaches, we found strong quality of evidence for interventions focusing on "changes in working time arrangements" and moderate quality of evidence for "influence on work tasks or work organization", "health care approach changes", and "improvements of the psychosocial work environment". Regarding outcomes, we found strong quality of evidence for interventions about "burnout" and moderate quality evidence for "various health and wellbeing outcomes". For all other types of interventions, quality of evidence was either low or inconclusive, including interventions on retention.

Conclusions: This overview of reviews identified strong or moderate quality of evidence for the effectiveness of organizational-level interventions for four specific intervention approaches and two health outcomes. This suggests that the work environment and the health of employees can be improved by certain organizational-level interventions. We need more research, especially about implementation and context, to improve the evidence.

研究目的本研究旨在系统回顾组织层面的干预措施在改善社会心理工作环境、工人健康和留任方面的有效性:我们对 2000 年至 2020 年间发表的有关组织层面干预措施的系统性综述进行了概述。我们系统地检索了学术数据库,筛选了参考文献列表,并联系了专家,共获得 27 736 条记录。在符合条件的 76 篇综述中,我们排除了 24 篇质量较差的综述,得出了 52 篇质量中等(32 篇)或较强(20 篇)的综述,涉及 957 项主要研究。我们根据综述的质量、结果的一致性以及对照研究的比例来评估证据的质量:在 52 篇综述中,30 篇研究了特定的干预方法,22 篇研究了特定的结果。关于干预方法,我们发现以 "改变工作时间安排 "为重点的干预措施的证据质量较高,而 "影响工作任务或工作组织"、"改变医疗保健方法 "和 "改善社会心理工作环境 "的证据质量中等。在结果方面,我们发现 "职业倦怠 "干预措施的证据质量较高,"各种健康和福利结果 "的证据质量中等。对于所有其他类型的干预措施,证据的质量要么很低,要么没有定论,包括对留任的干预措施:本综述为组织层面的干预措施对四种特定干预方法和两种健康结果的有效性提供了较强或中等质量的证据。这表明,某些组织层面的干预措施可以改善员工的工作环境和健康状况。我们需要更多的研究,特别是关于实施和背景的研究,以完善证据。
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引用次数: 4
How to improve intervention research on the psychosocial work environment? 如何改进对社会心理工作环境的干预研究?
IF 6.3 2区 医学 Q1 Medicine Pub Date : 2023-07-01 Epub Date: 2023-06-25 DOI: 10.5271/sjweh.4107
Alex Burdorf
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引用次数: 0
Between-occupation differences in work-related COVID-19 mitigation strategies over time: Analysis of the Virus Watch Cohort in England and Wales. 与工作相关的 COVID-19 缓解策略随时间推移的职业间差异:英格兰和威尔士病毒观察队列分析。
IF 4.7 2区 医学 Q1 Medicine Pub Date : 2023-07-01 Epub Date: 2023-04-17 DOI: 10.5271/sjweh.4092
Sarah Beale, Alexei Yavlinsky, Susan Hoskins, Vincent Nguyen, Thomas Byrne, Wing Lam Erica Fong, Jana Kovar, Martie Van Tongeren, Robert W Aldridge, Andrew Hayward

Objectives: COVID-19 mitigations have had a profound impact on workplaces, however, multisectoral comparisons of how work-related mitigations were applied are limited. This study aimed to investigate (i) occupational differences in the usage of key work-related mitigations over time and (ii) workers' perceptions of these mitigations.

Methods: Employed/self-employed Virus Watch study participants (N=6279) responded to a mitigation-related online survey covering the periods of December 2020-February 2022. Logistic regression was used to investigate occupation- and time-related differences in the usage of work-related mitigation methods. Participants' perceptions of mitigation methods were investigated descriptively using proportions.

Results: Usage of work-related mitigation methods differed between occupations and over time, likely reflecting variation in job roles, workplace environments, legislation and guidance. Healthcare workers had the highest predicted probabilities for several mitigations, including reporting frequent hand hygiene [predicted probability across all survey periods 0.61 (95% CI 0.56-0.66)] and always wearing face coverings [predicted probability range 0.71 (95% CI 0.66-0.75) - 0.80 (95% CI 0.76-0.84) across survey periods]. There were significant cross-occupational trends towards reduced mitigations during periods of less stringent national restrictions. The majority of participants across occupations (55-88%) agreed that most mitigations were reasonable and worthwhile even after the relaxation of national restrictions; agreement was lower for physical distancing (39-44%).

Conclusions: While usage of work-related mitigations appeared to vary alongside stringency of national restrictions, agreement that most mitigations were reasonable and worthwhile remained substantial. Further investigation into the factors underlying between-occupational differences could assist pandemic planning and prevention of workplace COVID-19 transmission.

目标:COVID-19 减缓措施对工作场所产生了深远的影响,然而,对如何应用与工作相关的减缓措施进行多部门比较却很有限。本研究旨在调查:(i) 随着时间的推移,使用主要工作相关缓解措施的职业差异;(ii) 工人对这些缓解措施的看法:受雇/自雇的病毒观察研究参与者(N=6279)对 2020 年 12 月至 2022 年 2 月期间与缓解措施相关的在线调查做出了回复。采用逻辑回归法调查与工作相关的缓解方法使用情况中与职业和时间相关的差异。使用比例对参与者对缓解方法的看法进行了描述性调查:与工作相关的缓解方法的使用情况因职业和时间而异,这可能反映了工作角色、工作场所环境、立法和指导方面的差异。医疗保健工作者使用几种缓解方法的预测概率最高,包括经常报告手部卫生[在所有调查期间的预测概率为 0.61 (95% CI 0.56-0.66)]和总是戴面罩[在所有调查期间的预测概率范围为 0.71 (95% CI 0.66-0.75) - 0.80 (95% CI 0.76-0.84)]。在国家限制措施不那么严格的时期,跨职业的减灾趋势非常明显。各职业的大多数参与者(55-88%)都认为,即使在国家限制放宽后,大多数缓解措施也是合理和值得的;但对物理距离的认同度较低(39-44%):结论:虽然与工作相关的缓解措施的使用似乎随着国家限制的严格程度而变化,但大多数缓解措施是合理和值得的这一共识仍然很大。对造成职业间差异的因素进行进一步调查有助于制定大流行规划和预防工作场所的 COVID-19 传播。
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引用次数: 0
The impact of COVID-19 lockdown restrictions on the short-term association between in-vehicle particulate pollutants and the respiratory health of Parisian taxi drivers. COVID-19封锁限制对车内颗粒污染物与巴黎出租车司机呼吸健康之间短期关联的影响。
IF 6.3 2区 医学 Q1 Medicine Pub Date : 2023-05-05 DOI: 10.2139/ssrn.4048904
Melissa Hachem, L. Bensefa-Colas, I. Momas
OBJECTIVESThis study assessed the short-term associations between in-vehicle ultrafine particles (UFP) and black carbon (BC) concentrations and irritation symptoms and lung parameters of taxi drivers, pre- and post-lockdown.METHODSAs part of PUF-TAXI project, 33 taxi drivers were followed up during two typical working days. In-vehicle UFP and BC were continuously measured by monitoring instruments. Irritation symptoms during the working day were reported via an auto-questionnaire and lung function was assessed by a portable spirometer, pre- and post- work shift. Generalized estimating equations, adjusted for potential confounders, were used to study the association between air pollutants and health outcomes. Effect modification by measurement period (pre- and post-lockdown) was investigated.RESULTSUFP and BC concentrations inside taxi vehicles decreased significantly post- compared to pre-lockdown. Incidence of nose irritation was positively associated with in-vehicle UFP and BC levels pre-lockdown, when pollutant levels were higher, whereas no significant association was found post-lockdown. The decrease in the FEF25-75% (forced expiratory flow at 25-75% of the forced vital capacity) during the working day was significantly associated with in-taxi UFP levels before but not after lockdown. No association was found with BC. By contrast, incidence of eye irritation was significantly inversely associated with in-vehicle humidity, regardless of pollutant concentrations and the measurement period.CONCLUSIONSOur findings indicate that an upgrade in in-vehicle air quality could improve respiratory health. This study showed that the magnitude of the incidence of nasal irritation and decrease in lung function depends on UFP concentrations the commuters are exposed to.
目的:本研究评估封锁前后出租车司机车内超细颗粒(UFP)和黑碳(BC)浓度与刺激症状和肺部参数之间的短期关系。方法作为PUF-TAXI项目的一部分,对33名出租车司机在两个典型工作日内进行随访。通过监测仪器连续测量车内UFP和BC。工作期间的刺激症状通过自动问卷报告,肺功能通过便携式肺活量计评估,工作前和工作后轮班。对潜在混杂因素进行调整后的广义估计方程用于研究空气污染物与健康结果之间的关系。考察了测定期(封前和封后)对效果的影响。结果与封城前相比,封城后出租车内fp和BC浓度显著降低。在封城前,当污染物水平较高时,鼻子刺激的发生率与车内UFP和BC水平呈正相关,而封城后则没有发现显著关联。工作日内FEF25-75%(用力呼气流量为用力肺活量的25-75%)的下降与封锁前(而非封锁后)出租车内UFP水平显著相关。未发现与BC相关。相比之下,无论污染物浓度和测量时间如何,眼睛刺激的发生率与车内湿度呈显著负相关。结论提高车内空气质量可促进呼吸道健康。这项研究表明,鼻刺激和肺功能下降的发生率取决于通勤者暴露于UFP浓度。
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引用次数: 0
The importance of occupation in the development of the COVID-19 pandemic. 职业在 COVID-19 大流行病发展过程中的重要性。
IF 6.3 2区 医学 Q1 Medicine Pub Date : 2023-05-01 Epub Date: 2023-04-12 DOI: 10.5271/sjweh.4094
Alex Burdorf, Reiner Rugulies
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引用次数: 0
Integrated mental healthcare and vocational rehabilitation for people on sick leave with stress-related disorders: 24-month follow-up of the randomized IBBIS trial. 为有压力相关障碍的病假人员提供综合心理保健和职业康复服务:IBBIS 随机试验 24 个月的随访。
IF 6.3 2区 医学 Q1 Medicine Pub Date : 2023-05-01 Epub Date: 2023-03-05 DOI: 10.5271/sjweh.4084
Andreas Hoff, Rie Mandrup Poulsen, Jonas Peter Fisker, Carsten Hjorthøj, Merete Nordentoft, Anders Bo Bojesen, Lene Falgaard Eplov

Objectives: Integrating vocational rehabilitation and mental healthcare has shown effects on vocational outcomes during sick leave with common mental disorders. In a previous paper, we showed that a Danish integrated healthcare and vocational rehabilitation intervention (INT) had a surprisingly negative impact on vocational outcomes compared to service as usual (SAU) at 6- and 12-month follow-up. That was also the case with a mental healthcare intervention (MHC) tested in the same study. This article reports the 24-month follow-up results of that same study.

Method: A randomized, parallel-group, three-arm, multi-centre superiority trial was conducted to test the effectiveness of INT and MHC compared to SAU.

Results: In total, 631 persons were randomized. Contrary to our hypothesis, SAU showed faster return to work than both INT [hazard rate (HR) 1.39, P=0.0027] and MHC (HR 1.30, P=0.013) at 24-month follow-up. Overall, no differences were observed regarding mental health and functional level. Compared to SAU, we observed some health benefits of MHC, but not INT, at 6-month follow-up but not thereafter, and lower rates of employment at all follow-ups. Since implementation problems might explain the results of INT, we cannot conclude that INT is no better that SAU. The MHC intervention was implemented with good fidelity and did not improve return to work.

Conclusion: This trial does not support the hypothesis that INT lead to faster return to work. However, implementation failure may explain the negative results.

目的:将职业康复和精神保健结合起来对常见精神障碍患者病假期间的职业结果有影响。在之前的一篇论文中,我们发现丹麦的一项综合医疗保健和职业康复干预措施(INT)在 6 个月和 12 个月的随访中对职业结果的影响竟然不如常规服务(SAU)。在同一研究中测试的心理保健干预(MHC)也是如此。本文报告了该研究 24 个月的随访结果:方法:进行了一项随机、平行组、三臂、多中心的优越性试验,以检验 INT 和 MHC 与 SAU 相比的有效性:共有 631 人接受了随机试验。与我们的假设相反,在24个月的随访中,SAU比INT(危险率(HR)为1.39,P=0.0027)和MHC(HR为1.30,P=0.013)恢复工作的速度更快。总体而言,在心理健康和功能水平方面没有观察到差异。与 SAU 相比,我们在 6 个月的随访中观察到了 MHC 的一些健康益处,但没有观察到 INT 的益处,而且在所有随访中就业率都较低。由于实施问题可能会导致 INT 的结果,我们不能得出 INT 比 SAU 好的结论。MHC干预措施的实施情况良好,但并未改善重返工作岗位的情况:本试验并不支持 INT 可加快重返工作岗位的假设。然而,实施失败可能是出现负面结果的原因。
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引用次数: 0
The impact of occupational exposures on infection rates during the COVID-19 pandemic: a test-negative design study with register data of 207 034 Dutch workers. COVID-19 大流行期间职业暴露对感染率的影响:利用 207 034 名荷兰工人的登记数据进行的试验阴性设计研究。
IF 6.3 2区 医学 Q1 Medicine Pub Date : 2023-05-01 Epub Date: 2023-03-13 DOI: 10.5271/sjweh.4086
Iris Eekhout, Martie van Tongeren, Neil Pearce, Karen M Oude Hengel

Objective: This study aimed to investigate the effects of occupational exposures on the risk of a positive COVID-19 test, and whether this differed across pandemic waves.

Methods: Data from 207 034 workers from The Netherlands with test data on COVID-19 from June 2020 until August 2021 were available. Occupational exposure was estimated by using the eight dimensions of a COVID-19 job exposure matrix (JEM). Personal characteristics, household composition and residence area were derived from Statistics Netherlands. A test-negative design was applied in which the risk of a positive test was analyzed in a conditional logit model.

Results: All eight dimensions of occupational exposure included in the JEM increased the odds of a positive test for the entire study period and three pandemic waves [OR ranging from 1.09, (95% confidence interval (CI) 1.02-1.17) to 1.77 (95% CI 1.61-1.96)]. Adjusting for a previous positive test and other covariates strongly reduced the odds to be infected, but most dimensions remained at elevated risk. Fully adjusted models showed that contaminated work spaces and face covering were mostly relevant in the first two pandemic waves, whereas income insecurity showed higher odds in the third wave. Several occupations have a higher predicted value for a positive COVID-19 test, with variation over time. Discussion Occupational exposures are associated with a higher risk of a positive test, but variations over time exist in occupations with the highest risks. These findings provide insights for interventions among workers for future pandemic waves of COVID-19 or other respiratory epidemics.

目的:本研究旨在调查职业暴露对 COVID-19 检测呈阳性风险的影响,以及这种影响在不同的大流行浪潮中是否有所不同:本研究旨在调查职业暴露对 COVID-19 检测呈阳性风险的影响,以及这种影响在不同的大流行浪潮中是否有所不同:方法:从 2020 年 6 月到 2021 年 8 月,荷兰有 207 034 名工人提供了 COVID-19 检测数据。通过 COVID-19 工作暴露矩阵(JEM)的八个维度估算职业暴露。个人特征、家庭组成和居住地来自荷兰统计局。采用检测阴性设计,在条件对数模型中分析检测呈阳性的风险:在整个研究期间和三次大流行中,JEM 中包含的所有八个职业暴露维度都增加了检测呈阳性的几率[OR 从 1.09(95% 置信区间(CI)1.02-1.17)到 1.77(95% 置信区间(CI)1.61-1.96)不等]。对之前的阳性检测结果和其他协变量进行调整后,受感染的几率大大降低,但大多数方面的风险仍然较高。完全调整后的模型显示,受污染的工作场所和面部遮盖主要与前两次大流行有关,而收入无保障则在第三次大流行中显示出更高的几率。有几种职业的 COVID-19 检测呈阳性的预测值较高,且随时间而变化。讨论 职业暴露与检测呈阳性的较高风险有关,但在风险最高的职业中存在随时间变化的差异。这些发现为在未来的 COVID-19 大流行或其他呼吸道流行病中对工人进行干预提供了启示。
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Scandinavian journal of work, environment & health
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