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[Emergency medical services]. [紧急医疗服务]。
Pub Date : 2021-08-27 DOI: 10.1002/9781119756279
P. Júnior
Emergency medical services (EMS) professionals may work at any of four different levels: First responder, EMT–basic, EMT–intermediate, and paramedic. Upon successful completion of training, students are eligible for employment in many types of emergency medical systems nationwide—in fire departments, municipal services, private ambulance services, federal services, industry, hospital emergency departments, and hospital-based ambulance systems. The demand for EMS professionals is increasing.
紧急医疗服务(EMS)专业人员可以在四个不同级别中的任何一个级别工作:第一响应者、基本急救人员、中级急救人员和护理人员。在成功完成培训后,学生有资格在全国许多类型的紧急医疗系统中就业-消防部门,市政服务,私人救护车服务,联邦服务,工业,医院急诊科和医院救护车系统。对EMS专业人员的需求正在增加。
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引用次数: 6
[Gender Dysphoria in Children in Clinical Practice of Child and Adolescent Psychiatry]. [儿童与青少年精神病学临床实践中的儿童性别焦虑]。
Masaru Tateno, Hiroshi Ikeda

In Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), Gender dysphoria (GD) is defined as a marked incongruence between one's experienced/expressed gender and assigned gender. Clinical pictures of GD in children show marked diversity. Because of their limited ability to express themselves verbally, children with GD might not be able to describe their discomfort or distress about this incongruence. In contrast to GD in adulthood, GD in children could be alleviated in the natural course. Thus, the clinical diagnosis of GD in children should be made carefully. Distortion of gender identity is equal to prominent confusion of identity, and has a huge psychological burden on children with GD. In addition to the distress due to dysphoria about gender, children with GD could suffer from bullying at school, loneliness among school peers or even in their family, and feelings of disgust about their physical appearance that could cause decreased self-esteem and a sense of worthlessness. In 2015, the Ministry of Education, Culture, Sports, Science and Technology (MEXT) in Japan encouraged all school teachers to provide appropriate support at school to sexual minor- ity students, including students with GD. Furthermore, MEXT published a manual for school teachers to promote necessary interventions for such students at school. There are several papers reporting child cases of GD and comorbid psychiatric disorders. Among them, autism spectrum disorder (ASD) is one of the common comorbidities. Reflecting these conditions, recent review articles discuss possible associations between GD and ASD. In this paper, based on the first author's clinical experience, we describe the clinical symp- toms and diagnosis of GD in children, the relationship between GD and ASD, gender-related manifestations observed in ASD, and practical support for children with GD entering primary school.

在《精神疾病诊断与统计手册》第五版(DSM-5)中,性别不安(Gender dysphoria, GD)被定义为个人体验/表达的性别与生理性别之间的明显不一致。儿童GD的临床表现具有明显的多样性。因为他们的语言表达能力有限,GD患儿可能无法描述他们对这种不一致的不适或痛苦。与成人的焦虑相比,儿童的焦虑可以在自然过程中得到缓解。因此,小儿GD的临床诊断应慎重。性别认同的扭曲等同于身份认同的突出困惑,给GD患儿带来了巨大的心理负担。除了对性别的焦虑所带来的痛苦之外,患有性别焦虑的儿童还可能遭受学校欺凌,在学校同伴中甚至在家庭中感到孤独,以及对自己外表的厌恶感,这可能导致自尊下降和毫无价值感。2015年,日本教育、文化、体育、科学和技术部(MEXT)鼓励所有学校教师在学校为性未成年学生提供适当的支持,包括患有性别焦虑的学生。此外,ext还为学校教师出版了一份手册,以促进对学校中这类学生的必要干预。有几篇论文报道了儿童GD和共病精神障碍的病例。其中,自闭症谱系障碍(ASD)是常见的合并症之一。反映这些情况,最近的综述文章讨论了GD和ASD之间可能的联系。本文结合第一作者的临床经验,对儿童GD的临床症状和诊断、GD与ASD的关系、ASD中观察到的性别相关表现以及GD患儿进入小学后的实际支持进行了阐述。
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引用次数: 0
[The Enactment of "the Certified Public Psychologists Act" and the Issues to be Considered]. [《注册公共心理学家法》的制定及应考虑的问题]。
Kayoko Murase

In this thesis, the historic circumstancs of enactment of and the forthcoming issues related to "the Certified Public Psychologists Act" are reported."The Certified Public Psychologists Act" was established thanks to the united efforts of a great number of the persons concerned, and the Act is scheduled to take effect in September 2017."The Certified Public Psychologist" is an occupational register: it is a qualification without which a person is allowed to deliver relevant services, but not permitted to feign a "Certified Public Psychologist". And since the Certified Public Psychologist is a general qualification, psychologists with the qualification are allowed to work in various fields such as educational area, medical/clinical area, forensic/criminal area, and industrial/occupational area. Mental problems in the modern society arise, in many cases, from various multidimensional factors which are intertwined and mutually related. Psychologists, in offering professional support in actual settings, need to be aware of their accountability that theories and skills are right for the supports. In addition, a sense of balance is required in collaboration, or team approach. It is emphasized that enhancing the systems for training and education is an urgent issue because continuous exertion to improve the compre- hensive capacity as professionals for future is indispensable.

本文对《注册社会心理学家法》的制定历史背景和未来的相关问题进行了阐述。在众多相关人士的共同努力下,《注册心理医生法》得以制定,并计划于2017年9月生效。“注册社会心理学家”是一种职业注册:没有该资格的人可以提供相关服务,但不允许冒充“注册社会心理学家”。由于注册公共心理学家是一种一般资格,具有资格的心理学家被允许在各个领域工作,如教育领域、医疗/临床领域、法医/刑事领域和工业/职业领域。在许多情况下,现代社会的心理问题是由各种多方面的因素引起的,这些因素相互交织、相互关联。心理学家在实际环境中提供专业支持时,需要意识到他们的责任,即理论和技能是适合支持的。此外,在协作或团队方法中需要一种平衡感。强调加强培训和教育制度建设是当务之急,因为不断努力提高未来专业人才的综合能力是必不可少的。
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引用次数: 0
[History and Further Discussion about Sports for People with Mental Health Problems]. [体育运动对精神疾病患者的历史及进一步探讨]。
Mamoru Onishi, Aya Yuasa

Our study mainly focused on summarizing the history and issues of the Sports for People with Mental Health Problems in Japan. Since it had been shifted from inpatients activity to a community based sport activity, it was the matter of great urgency for us to expand and rein- force its organizational foundation. The first competition of volleyball for people with mental health problems was held on 2001, and since 2008 the Sports for People with Mental Health Problems was officially admitted to participate in the National Sports Festival for People with an Impairment. The basic principal required protecting participants' privacy at the same level of other disabilities. We needed clearly define the qualification for participants, such as restricting participants only with disability certification issued by Japan Federation for Mental Health and Welfare. Furthermore, the first International Symposium/Meeting on Sport for People with Mental Health Problems was held in Tokyo in 2013, and the first international sports competi- tion for people with mental health problems was held in Japan, which was a milestone for the internationalization of World sport championship for people with mental health problems. For the upcoming the Japan Olympic and Paralympic in 2020, we recognize the public interests for sports for people with mental health problems. It is the great opportunity for us to trigger to popularize it. Since the activities with all three types of disability will grow not only in sports but also in other fields, it is very important to bring information together.

我们的研究主要集中在总结日本精神疾病患者体育运动的历史和问题。由于它已经从住院病人的活动转变为以社区为基础的体育活动,扩大和完善它的组织基础是我们迫在眉睫的事情。2001年举办了首届精神残疾人排球比赛。2008年起,精神残疾人体育正式被接纳参加全国残疾人体育节。基本原则要求在与其他残疾相同的水平上保护参与者的隐私。我们需要明确规定参与者的资格,例如限制只有获得日本精神卫生和福利联合会颁发的残疾证明的参与者。此外,2013年在东京举办了首届精神健康问题人群体育国际研讨会/会议,并在日本举办了首届精神健康问题人群国际体育比赛,这是世界精神健康问题人群体育锦标赛国际化的里程碑。对于即将到来的2020年日本奥运会和残奥会,我们认识到公众对精神健康问题患者体育运动的兴趣。对我们来说,这是一个很好的机会来推动它的普及。由于这三种残疾的活动不仅在体育领域而且在其他领域都会增加,因此将信息汇集在一起是非常重要的。
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引用次数: 0
[Expectations of Certified Psychologist in the Clinical Medicine System in Germany for Future Reference]. 【对德国临床医学体系中注册心理学家的期望与借鉴】。
Michihiko Hayashi, Kunihiko Funatsu

The legally defined certified psychologist is going to enter into the medical care system in 2019. In Germany, where the medical insurance is obligatory like in Japan, the authorized psy- chological psychologists are already functioning. There are similarities and differences between these psychological practitioners. German psychological psychologists are permitted both to have their own practices and to work in hospitals. Patients are allowed to visit them directly to be treated if they wish. The psychological psychologists are also authorized to claim medical treatment fee on medical insurance. The amount of their medical treatment fee is so much as that of psychiatric specialists on the whole. They are neither permitted to prescribe medicines nor to issue a medical certificate. They must ask them to a medical doctor. Like German's, neither prescription nor issue of a medical certificate are included in the authority of Japanese certified psychologists. They are not permitted to have a practice. It seems to be reasonable that every doctor can give them orders of psychotherapeutic treat- ments, as mentally sick patients are increasing in every field of clinical medicine. However it may probably be only psychiatrists who can understand and evaluate their profession appro- priately, therefore it would be suitable that psychiatrists participate somewhere in this order- ing and evaluating system. The medical treatment fee should be paid enough to the certified psychologists.

法律定义的注册心理学家将于2019年进入医疗保健系统。在德国,像日本一样,医疗保险是强制性的,授权的心理心理学家已经开始运作。这些心理从业者之间既有相似之处,也有不同之处。德国的心理心理学家既可以有自己的实践,也可以在医院工作。如果病人愿意,他们可以直接去医院接受治疗。心理医生也有权向医疗保险申领医疗费。他们的医疗费用与精神病专家的总体费用相当。他们既不被允许开药,也不被允许出具医疗证明。他们必须请他们去看医生。与德国一样,日本注册心理学家的权威范围既不包括处方,也不包括医疗证明。他们不允许行医。似乎每个医生都可以给他们开心理治疗的处方是合理的,因为精神病患者在临床医学的各个领域都在增加。然而,可能只有精神科医生才能恰当地理解和评估他们的职业,因此,精神科医生在这个排序和评估系统的某个地方参与是合适的。医疗费用应支付给注册心理医生。
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引用次数: 0
[A Questionnaire-based Study of Child Psychiatrists and Clinical Psychologists Regarding and Support for Children with Gender Identity Disorder and Sexual Problems]. [儿童精神病学家和临床心理学家关于性别认同障碍和性问题儿童的支持和支持的问卷调查]。
Chiho Ueno, Masaru Tateno, Hiroshi Nakayama

In 2010, the Ministry of Education, Culture, Sports, Science and Technology (MEXT) in Japan strongly recommended that students with gender identity disorder (GID) who had behavioral health concerns should consult a professional in their schools. Furthermore, in 2015, MEXT subsequently announced that it is important for sexual minority students, including students with GID, to receive more support from professionals through cooperation with medical institutions. However, there has been no nationwide clinical research done on sexual minority youth, so little is known about how to optimally care for them in medical practice. This study assessed the current status of medical care for children and adolescents with GID and other atypical sexual development. The authors surveyed certifying physicians and councilors (315 people in total) of The Japanese Society for Child and Adolescent Psychiatry. The question obtained basic demographic and practice information and allowed for free responses on topics such as opinion on consultation and medical care for GID and atypical sex- ual development in childhood and adolescence. One hundred twenty-seven, or 40.3%, of those surveyed responded. The average number of years of total clinical experience was 23.9, and the average number of years of child psychiatric clinical experience was 18.8 years. The number of child psychiatrists who provided con- sultation for GID and other sexual development including transvestism and gender dysphoria were 88 (68.5%) and 105 (81.9%), respectively. The consultants' most frequent clients, in descending order, were: individuals, parents, and school officials. Seventy-four (57.5%) child psychiatrists provide medical care for patients with GID. In the preschool and elementary school age groups, consultants served many more (assignment) males than (assignment) females with GID, whereas in the higher elementary school and later ages, consultants served more females than males with GID equally often. In junior high school and later ages, consultants served more females than males with GID. Eighty-seven (67.7%) of the child psychiatrists provided medical care for patients with other sexual development. Before and during the mid- dle elementary school ages and in the high school ages, consultants served more males than females with other typical development, whereas in higher grade elementary and junior high school ages, consultants served more females than males with other typical development. The free response sections revealed a diversity of opinions, clinical course, and cooperation with other institutions. At present, among child psychiatrists, there are many different perspectives on clinical care for GID and other sexual development. Therefore, it will be necessary to systematically examine current scientific evidence and to establish consensus on best practices for clinical management.

2010年,日本教育、文化、体育、科学和技术部(MEXT)强烈建议,有行为健康问题的性别认同障碍(GID)学生应该向学校的专业人士咨询。此外,2015年,文部科学省随后宣布,通过与医疗机构合作,让性少数群体学生,包括有性别认知障碍的学生,获得更多专业人士的支持,这一点很重要。然而,目前还没有针对性少数青少年的全国性临床研究,所以在医疗实践中如何对他们进行最佳护理知之甚少。本研究评估了患有GID和其他不典型性发育的儿童和青少年的医疗保健现状。作者调查了日本儿童和青少年精神病学协会的认证医生和顾问(共315人)。该问题获得了基本的人口和实践信息,并允许就诸如对儿童和青少年性别认知障碍症和非典型性发育的咨询和医疗保健的意见等主题作出自由答复。有127人(40.3%)做出了回应。总临床经验平均年数为23.9年,儿童精神病学临床经验平均年数为18.8年。为性别认知障碍和其他性发展(包括异装癖和性别焦虑症)提供咨询的儿童精神科医生分别为88名(68.5%)和105名(81.9%)。咨询师最常见的客户,按降序排列是:个人、家长和学校官员。74名(57.5%)儿童精神病医生为GID患者提供医疗服务。在学龄前和小学年龄组,咨询师服务的性别认知障碍患者(任务)男性多于(任务)女性,而在小学高年级和高年级,咨询师服务的性别认知障碍患者女性多于男性。在初中及以后的年龄阶段,咨询师服务的性别认知障碍患者女性多于男性。87名(67.7%)儿童精神病医生为有其他性发育的患者提供医疗服务。小学前期、初中阶段和高中阶段,具有其他典型发展的咨询师服务男性多于女性;小学高年级阶段和初中阶段,具有其他典型发展的咨询师服务女性多于男性。自由回答部分显示了不同的意见、临床过程和与其他机构的合作。目前,在儿童精神病学家中,对性别认知障碍和其他性发展的临床护理有许多不同的观点。因此,有必要系统地检查当前的科学证据,并就临床管理的最佳实践建立共识。
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引用次数: 0
[Minds Guide for Developing Clinical Practice Guidelines Ver. 2.0 by Japan Council for Quality Health Care -Practice of EBM-]. [日本卫生保健质量委员会制定的临床实践指南2.0版- EBM的实践]。
Ryota Hashimoto

Minds (Medical Information Network Distribution Service) is an information service provided by the Japan Council for Quality Health Care (JCQHC), a public interest incorporated foundation. The Minds guide for developing clinical practice guidelines was published in 2014. The aim of the Minds project is to help medical practitioners fully utilize information related to evidence-based medicine (EBM) in their practice. Minds also provides patients and the public with information to help understand the basics of diseases and share up-to-date evi- dence with doctors, on which modern medical practices are based. Overall, clinical practice guidelines are made up as follows : 1) a three-layered structure of guideline committees con- sisting of a managing committee, guideline creation team, and a systematic review team, 2) a clear description of the basis for an individual's judgment and COI, 3) evaluation of the body of evidence summarized for every outcome and study design in all selected research reports for each Clinical Question (CQ), and 4) not only the "benefit" but also the "harm" in the patient outcome caused by intervention are to be included in the evaluation. According to the Minds method, the Japanese Society of Neuropsychopharmacology has created a "Guidelines for Pharmacological Therapy of Schizophrenia." These guidelines were introduced to explain the characteristics of the Minds method in this paper. The Effectiveness of GUIdelines for Dissemination and Education in psychiatric treatment project (EGUIDE proj- ect) was also introduced to disseminate and evaluate these guidelines.

Minds(医疗信息网络分发服务)是由日本优质医疗保健委员会(JCQHC)提供的一项信息服务,该委员会是一个公共利益合并基金会。制定临床实践指南的Minds指南于2014年出版。Minds项目的目的是帮助医生在实践中充分利用与循证医学(EBM)相关的信息。Minds还向患者和公众提供信息,以帮助了解疾病的基本知识,并与医生分享现代医疗实践所依据的最新证据。总体而言,临床实践指引如下:1)指南委员会的三层结构,包括管理委员会、指南制定团队和系统审查团队;2)明确描述个人判断和COI的基础;3)评估针对每个临床问题(CQ)的所有选定研究报告中总结的每个结果和研究设计的证据体;4)干预对患者预后的影响不仅包括“受益”,还包括“危害”。根据Minds方法,日本神经精神药理学学会制定了“精神分裂症药物治疗指南”。本文介绍了这些准则来解释Minds方法的特点。同时介绍了精神科治疗传播教育指南的有效性项目(EGUIDE项目),以传播和评估这些指南。
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引用次数: 0
[Educational System for Certified Psychologists in General Hospitals]. [综合医院注册心理学家教育制度]。
Yoshifumi Nakashima

The certified psychologist is a cross-disciplinary profession ; thus, the qualification test and curriculum should cover not only medical but also non-medical areas. The number of men- tal health professionals working in medical areas is high. Knowledge and skills in the health care area are necessary for certified psychologists and candidates. Knowledge covers laws and systems of medical services, including medical safety and infection control, and medical knowledge at the non-professional/patient level. In the general medical area, skills of: 1) having multilevel perspectives, 2) understanding dynamics and collaborating, and 3) facilitating com- munication with difficulties, are necessary. When going down the clinical river, holding an OAR [Open, Available, Responsible] is significant, not only for those who working in the medical area but for everyone, because every certified psychologist is obligated to cooperate.

注册心理学家是一个跨学科的职业;因此,资格考试和课程不仅应涵盖医学领域,也应涵盖非医学领域。在医疗领域工作的男性心理健康专业人员数量很多。在卫生保健领域的知识和技能是必要的认证心理学家和候选人。知识涵盖法律和医疗服务体系,包括医疗安全和感染控制,以及非专业/患者层面的医学知识。在普通医学领域,需要具备以下技能:1)具有多层次的视角;2)理解动态和协作;3)在困难时促进沟通。在临床工作中,持有“开放、可用、负责”(Open, Available, Responsible)的态度是非常重要的,不仅对那些在医疗领域工作的人来说是如此,对每个人来说都是如此,因为每个获得认证的心理学家都有义务合作。
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引用次数: 0
[Medical Professionalism: A Thread of Guidance for Psychiatry]. [医学专业:精神病学指导思路]。
Yasushi Miyata

It is considered that professionalism is a virtue as a personal attribute, competency is an observable behavior, and professional identity formation is a form of socialization. Social accountability is believed to be an important attribute of medical professionalism. A true professional struggles with complicated and/or ambiguous clinical problems of our modern society, and he/she grows up in the course of managing such difficult cases with iterative reflection. A reflective practitioner is someone who can practice in such a way. A reflective practitioner dealing with social problems is a true professional. Significant Event Analysis (SEA) is one of most valuable learning strategies to become a reflective practitioner.

认为专业精神是一种美德,是一种个人属性,能力是一种可观察的行为,职业认同的形成是一种社会化的形式。社会责任被认为是医疗专业的一个重要属性。一个真正的专业人士与我们现代社会复杂和/或模糊的临床问题作斗争,他/她在处理这些困难的病例和反复反思的过程中成长。反思性实践者就是能够以这种方式练习的人。处理社会问题的反思性从业者是真正的专业人士。重要事件分析(SEA)是成为反思性实践者最有价值的学习策略之一。
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引用次数: 0
[An Adult Case of 22q11.2 Deletion Syndrome with Congenital Abnormalities and Neurodevelopmental Disorders, Which Remained Undiagnosed Until Presentation of Auditory Hallucinations]. [成人22q11.2缺失综合征合并先天性异常和神经发育障碍1例,直到出现幻听才确诊]。
Hidetaka Tamune, Fumichika Nishimura, Daisuke Koshiyama, Katsuhisa Yamada, Shinsuke Kondo, Yukiko Kano, Kiyoto Kasai

22q11.2 deletion syndrome (22q11.2 DS) is characterized by cardiac defects, abnormal facial features, thymic hypoplasia, cleft palate, and hypocalcemia, including DiGeorge syndrome (DGS), velocardiofacial syndrome (VCFS), and conotruncal anomaly face (CTAF) syndrome. Psychiatric symptoms were recently shown to be very common in patients with 22q11.2 DS, prompting greater interest in this syndrome. Early diagnosis during childhood based on a con- stellation of physical features is optimal ; however, as some patients remain undiagnosed until the presentation of other symptoms in adult life, psychiatrists are well advised to familiarize themselves with basic information concerning 22q11.2 DS. A 25-year-old woman presenting with auditory hallucinations was referred to A hospital for examination and treatment. Her family history revealed both paternal and maternal rela- tives with schizophrenia. At birth, she presented a cleft palate and ventricular septum defect. She first became ambulatory at age 4 and became verbal a year later. Her intelligence quotient was estimated at around 40 and mental retardation (DSM-IV) with autistic features was diag- nosed at age 7. After graduating from a special high school, she obtained fulltime employment in a workshop. However, auditory hallucinations began disrupting her life from 22 years of age. Although olanzapine temporarily alleviated her symptoms, the resultant extrapyramidal symp- toms worsened and she was referred to A hospital again at age 25. The patient presented with micrognathia and a flat nasal root and spoke a maximum of 3 words per sentence in a very high and indistinct tone. A cardiac defect (ventricular septal defect), scoliosis, and low platelets were also observed. The diagnosis of 22qll.2 DS was confirmed using fluorescence in situ hybridization (FISH). The patient and her family were subsequently introduced to a 22q11.2 DS patients' support group. Careful genetic counseling is paramount, but the diagnosis of 22q11.2 DS can make updated information, official aid, and access to support groups available to patients and their family. Emergency complications such as seizures due to hypocalcemia can also be anticipated. The comparatively late diagnosis of 22q11.2 DS in our patient, which went undetected until the presentation of auditory hallucinations, in the context of mental retardation with autis- tic features (DSM-IV) underscores the importance of detailed clinical observation. "One rare variant" possibly points out the essence of psychiatric pathophysiology. Moreover, 22q11.2 DS has been listed as an intractable disease in Japan since 2015. When patients present with neurodevelopmental disorders and schizophrenic symptoms, we should carefully observe their physical features for clues to the possible diagnosis of 22q11.2 DS.

22q11.2缺失综合征(22q11.2 DS)以心脏缺陷、面部特征异常、胸腺发育不全、腭裂和低钙血症为特征,包括DiGeorge综合征(DGS)、心面速度综合征(VCFS)和锥体锥体异常脸(CTAF)综合征。精神症状最近在22q11.2 DS患者中非常常见,这促使人们对该综合征产生了更大的兴趣。在儿童时期基于身体特征的早期诊断是最佳的;然而,由于一些患者直到成年后出现其他症状才被诊断出来,因此建议精神科医生熟悉有关22q11.2 DS的基本信息。一名25岁女子因出现幻听被转到A医院接受检查和治疗。她的家族史显示父亲和母亲的亲属都患有精神分裂症。出生时,她表现出腭裂和室间隔缺损。她在4岁时开始走动,一年后开始说话。她的智商估计在40左右,在7岁时被诊断为智力迟钝(DSM-IV),并伴有自闭症特征。从一所特殊高中毕业后,她在一家车间找到了一份全职工作。然而,从22岁开始,幻听开始扰乱她的生活。虽然奥氮平暂时缓解了她的症状,但由此产生的锥体外系症状恶化,她在25岁时再次被转到A医院。患者表现为小颌,鼻根扁平,每句话最多3个单词,音调非常高且不清晰。心脏缺损(室间隔缺损)、脊柱侧凸和低血小板也被观察到。22qll的诊断用荧光原位杂交法(FISH)证实了DS。患者及其家人随后被介绍到22q11.2退行性痴呆患者支持小组。仔细的遗传咨询是至关重要的,但22q11.2 DS的诊断可以为患者及其家人提供最新的信息,官方援助和支持团体。紧急并发症,如癫痫发作由于低钙也可以预期。本例患者22q11.2 DS的诊断相对较晚,直到出现幻听才被发现,在自闭症特征的智力迟钝背景下(DSM-IV),强调了详细临床观察的重要性。“一个罕见的变异”可能指出了精神病理生理学的本质。此外,22q11.2 DS自2015年起在日本被列为难治性疾病。当患者出现神经发育障碍和精神分裂症症状时,我们应仔细观察其身体特征,为22q11.2 DS的可能诊断提供线索。
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Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica
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