Pub Date : 2023-10-01DOI: 10.26554/sti.2023.8.4.640-646
Noora H. Al-Zobiadi, Ammar A. Habeeb, Awatif S. Jasim
The chemical reduction method (CRM) can produce high purity nanoparticles, it is a down-top chemical method based on the principle of salt reduction, this method is used in this work to synthesis copper nanoparticals (CuPNs) by use different concentrations of copper nitrate. The properties of the prepared nanoparticles were studied by fourier transform infrared (FTIR) and ultraviolet-visible (UV-Vis) spectroscopy were used to measure the absorbance spectra of the produced particles. According to the scanning electron microscope (SEM), the particles’ diameters range from (61.64 to 49.25) nm. According to X-ray diffraction, the particles exhibit a face monoclinic crystal structure (FCC). According to the transmission electron microscope findings, the particles are asymmetrically spherical in shape.
{"title":"Studying the Structure Properties of Copper Nanoparticles Prepared by Chemical Reduction Method","authors":"Noora H. Al-Zobiadi, Ammar A. Habeeb, Awatif S. Jasim","doi":"10.26554/sti.2023.8.4.640-646","DOIUrl":"https://doi.org/10.26554/sti.2023.8.4.640-646","url":null,"abstract":"The chemical reduction method (CRM) can produce high purity nanoparticles, it is a down-top chemical method based on the principle of salt reduction, this method is used in this work to synthesis copper nanoparticals (CuPNs) by use different concentrations of copper nitrate. The properties of the prepared nanoparticles were studied by fourier transform infrared (FTIR) and ultraviolet-visible (UV-Vis) spectroscopy were used to measure the absorbance spectra of the produced particles. According to the scanning electron microscope (SEM), the particles’ diameters range from (61.64 to 49.25) nm. According to X-ray diffraction, the particles exhibit a face monoclinic crystal structure (FCC). According to the transmission electron microscope findings, the particles are asymmetrically spherical in shape.","PeriodicalId":21644,"journal":{"name":"Science and Technology Indonesia","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135407066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In a weighted connected graph, the shortest total path length spanning tree problem is a problem when we need to discover the spanning tree with the lowest total cost of all pairwise distances between its vertices. This problem is also known as the minimum routing cost spanning tree (MRCST). In this study, we will discuss the Modified Sollin and Modified Dijkstra Algorithms to solve that problem which implemented on 300 problems are complete graphs of orders 10 to 100 in increments of 10, where every order consists of 30 problems. The results show that the performance of the Modified Dijkstra and the Modified Sollin Algorithms are slightly similar. On orders 10, 20, 30, 60, and 80, the Modified Dijkstra Algorithm performs better than the Modified Sollin, however on orders 40, 50, 70, 90, and 100, the Modified Sollin performs better.
{"title":"Solving the Shortest Total Path Length Spanning Tree Problem Using the Modified Sollin and Modified Dijkstra Algorithms","authors":"Wamiliana Wamiliana, Reni Permata Sari, Astri Reformasari, Jani Suparman, Akmal Junaidi","doi":"10.26554/sti.2023.8.4.684-690","DOIUrl":"https://doi.org/10.26554/sti.2023.8.4.684-690","url":null,"abstract":"In a weighted connected graph, the shortest total path length spanning tree problem is a problem when we need to discover the spanning tree with the lowest total cost of all pairwise distances between its vertices. This problem is also known as the minimum routing cost spanning tree (MRCST). In this study, we will discuss the Modified Sollin and Modified Dijkstra Algorithms to solve that problem which implemented on 300 problems are complete graphs of orders 10 to 100 in increments of 10, where every order consists of 30 problems. The results show that the performance of the Modified Dijkstra and the Modified Sollin Algorithms are slightly similar. On orders 10, 20, 30, 60, and 80, the Modified Dijkstra Algorithm performs better than the Modified Sollin, however on orders 40, 50, 70, 90, and 100, the Modified Sollin performs better.","PeriodicalId":21644,"journal":{"name":"Science and Technology Indonesia","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135406735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.26554/sti.2023.8.4.626-631
Mokhamad Yusup Nur Khakim, Takeshi Tsuji, Erni Erni, Akhmad Aminudin Bama, Frinsyah Virgo, Muhammad Irfan, Azhar Kholiq Affandi, Toshifumi Matsuoka
The Muara Laboh geothermal field lies in a South Solok basin zone, West Sumatra, Indonesia. Production and reinjection of geothermal fluids into the underground reservoir commonly induce crustal deformation. The study area is covered by 63.8% plantation, primary, and secondary forests, which limit the ability of conventional InSAR techniques. Therefore, an Intermittent Small BASeline Subset (ISBAS) analysis has been performed to estimate line-of sight (LOS) displacement time series due to geothermal production using the Sentinel-1 dataset between 8 March 2021 and 15 March 2022. The localized subsidence with ∼30 mm/yr rate over this tropical geothermal field has been revealed by using the ISBAS. The subsidence coincides with an area of the Muara Laboh geothermal reservoir. We suggest that geothermal production induced subsidence. In addition, the deformation in this geothermal field was controlled by faults and seasonally influenced by rainfall. Therefore, deformation variation was correlated with fluctuations in rainfall patterns. The geothermal reservoir system exhibited elastic expansion in response to seasonal recharge events during the rainy season.
Muara Laboh地热田位于印度尼西亚西苏门答腊岛南索洛克盆地带。地下储层地热流体的开采和回注通常会引起地壳变形。研究区人工林、原生林和次生林覆盖率为63.8%，这限制了常规InSAR技术的能力。因此，使用2021年3月8日至2022年3月15日期间的Sentinel-1数据集，进行了间歇性小基线子集(ISBAS)分析，以估计地热生产引起的视线(LOS)位移时间序列。利用ISBAS揭示了该热带地热田的局部沉降速率为~ 30 mm/yr。下沉与Muara Laboh地热储层的区域一致。我们认为地热生产引起了下沉。此外，该地热田的变形受断裂控制，并受降水的季节性影响。因此，变形变化与降雨模式的波动相关。在雨季，地热储层系统对季节性补给事件表现出弹性扩张的响应。
{"title":"Monitoring the Muara Laboh Geothermal Field in Indonesia using the ISBAS Method with Sentinel-1 SAR Images","authors":"Mokhamad Yusup Nur Khakim, Takeshi Tsuji, Erni Erni, Akhmad Aminudin Bama, Frinsyah Virgo, Muhammad Irfan, Azhar Kholiq Affandi, Toshifumi Matsuoka","doi":"10.26554/sti.2023.8.4.626-631","DOIUrl":"https://doi.org/10.26554/sti.2023.8.4.626-631","url":null,"abstract":"The Muara Laboh geothermal field lies in a South Solok basin zone, West Sumatra, Indonesia. Production and reinjection of geothermal fluids into the underground reservoir commonly induce crustal deformation. The study area is covered by 63.8% plantation, primary, and secondary forests, which limit the ability of conventional InSAR techniques. Therefore, an Intermittent Small BASeline Subset (ISBAS) analysis has been performed to estimate line-of sight (LOS) displacement time series due to geothermal production using the Sentinel-1 dataset between 8 March 2021 and 15 March 2022. The localized subsidence with ∼30 mm/yr rate over this tropical geothermal field has been revealed by using the ISBAS. The subsidence coincides with an area of the Muara Laboh geothermal reservoir. We suggest that geothermal production induced subsidence. In addition, the deformation in this geothermal field was controlled by faults and seasonally influenced by rainfall. Therefore, deformation variation was correlated with fluctuations in rainfall patterns. The geothermal reservoir system exhibited elastic expansion in response to seasonal recharge events during the rainy season.","PeriodicalId":21644,"journal":{"name":"Science and Technology Indonesia","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135406741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.26554/sti.2023.8.4.570-578
Zati Aqmar Zaharudin, Adibah Shuib, Rieske Hadianti, Zahari Md Rodzi
Sustainable waste management is essential for any nation. To limit the amount of waste transported to landfills, it is critical to handle waste properly, notably by segregating recyclables from discarded waste. Waste separation at the source is critical to ensure that generated waste is not completely directed to landfill. The practice of waste separation would initiate the recycling process, which is able to reduce the amount of waste sent to the landfill. Recycling is critical to the achievement of two Sustainable Development Goals (SDGs), 11 and 12, for which Malaysian government has set the goal for recycling rates to reach 40% by 2025 in 2022, the rate has reached 33.17%. In Malaysia, recyclables are either collected on-site or sent to a designated facility. The separation at source activity is essential for developing recycling practices. Despite being the largest waste generator, public engagement, particularly at the household level, has remained low, most likely due to recycling facility availability and accessibility issues. Thus, improving public access to the facility would lead to increased recycling rates. In this study, a mixed integer linear programming model is proposed to locate recycling facilities in optimal locations that cover the most amount of waste generated by households. The capacity level is induced to ensure that the dropped-off recyclables are proportionate at the designated facility locations. Several experiments were conducted for validity purposes, and the proposed model was applied in a Malaysian urban area, namely Nilai. As a result, the proposed model was able to locate the optimal locations with the requisite capacity level while ensuring coverage for most Nilai households.
{"title":"Towards Sustainable City: A Covering Model for Recycling Facility Location-allocation in Nilai, Malaysia","authors":"Zati Aqmar Zaharudin, Adibah Shuib, Rieske Hadianti, Zahari Md Rodzi","doi":"10.26554/sti.2023.8.4.570-578","DOIUrl":"https://doi.org/10.26554/sti.2023.8.4.570-578","url":null,"abstract":"Sustainable waste management is essential for any nation. To limit the amount of waste transported to landfills, it is critical to handle waste properly, notably by segregating recyclables from discarded waste. Waste separation at the source is critical to ensure that generated waste is not completely directed to landfill. The practice of waste separation would initiate the recycling process, which is able to reduce the amount of waste sent to the landfill. Recycling is critical to the achievement of two Sustainable Development Goals (SDGs), 11 and 12, for which Malaysian government has set the goal for recycling rates to reach 40% by 2025 in 2022, the rate has reached 33.17%. In Malaysia, recyclables are either collected on-site or sent to a designated facility. The separation at source activity is essential for developing recycling practices. Despite being the largest waste generator, public engagement, particularly at the household level, has remained low, most likely due to recycling facility availability and accessibility issues. Thus, improving public access to the facility would lead to increased recycling rates. In this study, a mixed integer linear programming model is proposed to locate recycling facilities in optimal locations that cover the most amount of waste generated by households. The capacity level is induced to ensure that the dropped-off recyclables are proportionate at the designated facility locations. Several experiments were conducted for validity purposes, and the proposed model was applied in a Malaysian urban area, namely Nilai. As a result, the proposed model was able to locate the optimal locations with the requisite capacity level while ensuring coverage for most Nilai households.","PeriodicalId":21644,"journal":{"name":"Science and Technology Indonesia","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135408340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.26554/sti.2023.8.4.647-653
Mardiyanto Mardiyanto, Budi Untari, Ady Mara, Diko Fahri Ferdiansyah
Research to increase the solubility of active pharmaceutical ingredients is usually conducted by reducing the particle size. This research is one side that used the solid dispersion systems to increase solubility, especially on macrolide antibiotics for which there is still little information. The co-grinding technique on azithromycin-chitosan-alginate was chosen to produce a solid dispersion system. The parameters observed were changes in crystal structure, FTIR spectral patterns, morphological changes, and dissolution profile changes. The results of this research showed a change in the pattern of X-diffraction of azithromycin, physical interaction between azithromycin and the polymer, changes in the image of surface of solid dispersions, the solubility of solid dispersions in simulated-intestinal-fluid (SIF) solutions, and an increase in the dissolution rate of azithromycin indicating that the co-grinding technique to produce solid dispersions can increase the solubility of azithromycin.
{"title":"Formation of Hydroxyl-Amide Solid Dispersion Involving Azithromycin and Chitosan-Alginate Biopolymer to Increase the Dissolution Rate of Azithromycin","authors":"Mardiyanto Mardiyanto, Budi Untari, Ady Mara, Diko Fahri Ferdiansyah","doi":"10.26554/sti.2023.8.4.647-653","DOIUrl":"https://doi.org/10.26554/sti.2023.8.4.647-653","url":null,"abstract":"Research to increase the solubility of active pharmaceutical ingredients is usually conducted by reducing the particle size. This research is one side that used the solid dispersion systems to increase solubility, especially on macrolide antibiotics for which there is still little information. The co-grinding technique on azithromycin-chitosan-alginate was chosen to produce a solid dispersion system. The parameters observed were changes in crystal structure, FTIR spectral patterns, morphological changes, and dissolution profile changes. The results of this research showed a change in the pattern of X-diffraction of azithromycin, physical interaction between azithromycin and the polymer, changes in the image of surface of solid dispersions, the solubility of solid dispersions in simulated-intestinal-fluid (SIF) solutions, and an increase in the dissolution rate of azithromycin indicating that the co-grinding technique to produce solid dispersions can increase the solubility of azithromycin.","PeriodicalId":21644,"journal":{"name":"Science and Technology Indonesia","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135408073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-06DOI: 10.26554/sti.2023.8.3.382-387
F. Fitrya, Annisa Amriani, Rennie Puspa Novita, Fadila Kurnia
Dendrophthoe pentandra (Loranthaceae) is a semi-parasitic plant with several diverse metabolites and biological activities and is widely used in traditional medicine. This study aims to evaluate the gastroprotective effectiveness of the ethanol extract of D. pentandra leaves in animals induced by an acute peptic ulcer with absolute ethanol. The gastroprotective effect of the extract (100, 250 and 500 mg/kg doses) was evaluated through ulcer index parameters, physicochemical properties of gastric fluid, and histopathological analysis. The study results of the study showed that the ethanol extract of D. pentandra leaves at a dose of 500 mg/kg could provide a protective effect equivalent to omeprazole. Histopathological analysis proved the improvement of the mucous membrane structure in the animals pre-treated with the extract. Based on these findings, it can be concluded that the ethanol extract of D. pentandra leaves is effective as an anti-ulcer drug, so it is feasible to be developed as a gastroprotective from herbal.
{"title":"Gastroprotective Effects of Dendropthoe pentandra Leaf Ethanol Extract on Peptic Ulcer Animal Models","authors":"F. Fitrya, Annisa Amriani, Rennie Puspa Novita, Fadila Kurnia","doi":"10.26554/sti.2023.8.3.382-387","DOIUrl":"https://doi.org/10.26554/sti.2023.8.3.382-387","url":null,"abstract":"Dendrophthoe pentandra (Loranthaceae) is a semi-parasitic plant with several diverse metabolites and biological activities and is widely used in traditional medicine. This study aims to evaluate the gastroprotective effectiveness of the ethanol extract of D. pentandra leaves in animals induced by an acute peptic ulcer with absolute ethanol. The gastroprotective effect of the extract (100, 250 and 500 mg/kg doses) was evaluated through ulcer index parameters, physicochemical properties of gastric fluid, and histopathological analysis. The study results of the study showed that the ethanol extract of D. pentandra leaves at a dose of 500 mg/kg could provide a protective effect equivalent to omeprazole. Histopathological analysis proved the improvement of the mucous membrane structure in the animals pre-treated with the extract. Based on these findings, it can be concluded that the ethanol extract of D. pentandra leaves is effective as an anti-ulcer drug, so it is feasible to be developed as a gastroprotective from herbal.","PeriodicalId":21644,"journal":{"name":"Science and Technology Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44672760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-06DOI: 10.26554/sti.2023.8.3.429-435
M. Muharni, E. Nurnawati, H. Yohandini, H. Widjajanti
Industrial waste from Jumputan cloth production pose a significant risk to environmental safety due to their toxic synthetic dye content. Several studies have shown that the presence of bacteria in these materials plays a very important role in decolorization process of the constituent dye. Therefore, this study aims to isolate bacteria with the ability to decolorize direct red 80 from Jumputan cloth industrial waste. Characterization of isolates was carried out macroscopically, microscopically, and biochemically, followed by molecular identification using the 16S rRNA gene. Decolorization effects of the samples on red dye 80 were then assessed using a spectrophotometer at a maximum wavelength of 528 nm. The results showed that 6 bacteria isolates can degrade dye, with decolorizing power ranging from 26.33±0.94 - 73.67±0.47. The highest potential for decolorizing waste synthetic dye is seen in isolate BD 05. Phylogenetic analysis showed that there were 3 genera of bacteria among the samples obtained, namely Bacillus, Aeromonas, and Pseudomonas. These bacteria were closely related to Bacillus tropicus, Areomonas jandaei, and Pseudomonas stutzeri. Pseudomonas stutzeri (BD 05) has the highest potential in handling jumputan industrial waste.
{"title":"Isolation and Molecular Identification of Direct Red 80 Synthetic Dye Degradation Bacteria from Palembang Indonesia Jumputan Cloth Industrial Waste","authors":"M. Muharni, E. Nurnawati, H. Yohandini, H. Widjajanti","doi":"10.26554/sti.2023.8.3.429-435","DOIUrl":"https://doi.org/10.26554/sti.2023.8.3.429-435","url":null,"abstract":"Industrial waste from Jumputan cloth production pose a significant risk to environmental safety due to their toxic synthetic dye content. Several studies have shown that the presence of bacteria in these materials plays a very important role in decolorization process of the constituent dye. Therefore, this study aims to isolate bacteria with the ability to decolorize direct red 80 from Jumputan cloth industrial waste. Characterization of isolates was carried out macroscopically, microscopically, and biochemically, followed by molecular identification using the 16S rRNA gene. Decolorization effects of the samples on red dye 80 were then assessed using a spectrophotometer at a maximum wavelength of 528 nm. The results showed that 6 bacteria isolates can degrade dye, with decolorizing power ranging from 26.33±0.94 - 73.67±0.47. The highest potential for decolorizing waste synthetic dye is seen in isolate BD 05. Phylogenetic analysis showed that there were 3 genera of bacteria among the samples obtained, namely Bacillus, Aeromonas, and Pseudomonas. These bacteria were closely related to Bacillus tropicus, Areomonas jandaei, and Pseudomonas stutzeri. Pseudomonas stutzeri (BD 05) has the highest potential in handling jumputan industrial waste.","PeriodicalId":21644,"journal":{"name":"Science and Technology Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47391301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-06DOI: 10.26554/sti.2023.8.3.344-352
N. Nerdy, Linda Margata, N. Zebua, P. Lestari, T. K. Bakri, Faisal Yusuf, Vonna Aulianshah
The development of a method for identification and determination of thiamphenicol by Fourier Transform Infrared will provide convenience to developers because it is fast and easy for analysis. The research was carried out by utilizing the solubility of thiamphenicol in methanol with three stages, namely method development, sample analysis, and method validation. The method development stage showed that the specific peak of thiamphenicol was at a peak with a wavenumber of 1694.1 cm−1; this specific peak of thiamphenicol was used for qualitative analysis and quantitative analysis of thiamphenicol in the capsule dosage form. The sample analysis showed that all analyzed thiamphenicol in capsule dosage form showed good results both qualitatively and quantitatively. Qualitatively all the samples analyzed showed a specific peak at specific positions and specific wavenumbers. These results meet the requirements for containing thiamphenicol in the dosage form. Quantitatively all the samples analyzed ranged from 97.97% to 102.24% by peak height and peak area. These results meet the requirements for active substance levels in general preparations within 90.0% to 110.0%. The method validation for peak height and peak area showed that the accuracy parameter had a recovery percentage of 100.28% and 100.41% (between 98.0% to 102.0%), the precision parameter with a relative standard deviation of 0.31% and 0.37% (not more than 2.0%), and the linearity parameter with a correlation coefficient of 0.9999 and 0.9997 (not less than 0.99). The limit of detection value was 0.2971 mg/mL and 0.5338 mg/mL, the limit of quantitation value was 0.9004 mg/mL and 1.6176 mg/mL, the range for both was 80% to 120%, and the specificity for both met the requirement. The Fourier Transform Infrared method has been successfully developed, applied, and validated for qualitative analysis and quantitative analysis of thiamphenicol in capsule dosage form.
{"title":"Development and Validation of Fast and Simple Fourier Transform Infrared Spectrophotometric Method for Analysis of Thiamphenicol in Capsule Dosage Form","authors":"N. Nerdy, Linda Margata, N. Zebua, P. Lestari, T. K. Bakri, Faisal Yusuf, Vonna Aulianshah","doi":"10.26554/sti.2023.8.3.344-352","DOIUrl":"https://doi.org/10.26554/sti.2023.8.3.344-352","url":null,"abstract":"The development of a method for identification and determination of thiamphenicol by Fourier Transform Infrared will provide convenience to developers because it is fast and easy for analysis. The research was carried out by utilizing the solubility of thiamphenicol in methanol with three stages, namely method development, sample analysis, and method validation. The method development stage showed that the specific peak of thiamphenicol was at a peak with a wavenumber of 1694.1 cm−1; this specific peak of thiamphenicol was used for qualitative analysis and quantitative analysis of thiamphenicol in the capsule dosage form. The sample analysis showed that all analyzed thiamphenicol in capsule dosage form showed good results both qualitatively and quantitatively. Qualitatively all the samples analyzed showed a specific peak at specific positions and specific wavenumbers. These results meet the requirements for containing thiamphenicol in the dosage form. Quantitatively all the samples analyzed ranged from 97.97% to 102.24% by peak height and peak area. These results meet the requirements for active substance levels in general preparations within 90.0% to 110.0%. The method validation for peak height and peak area showed that the accuracy parameter had a recovery percentage of 100.28% and 100.41% (between 98.0% to 102.0%), the precision parameter with a relative standard deviation of 0.31% and 0.37% (not more than 2.0%), and the linearity parameter with a correlation coefficient of 0.9999 and 0.9997 (not less than 0.99). The limit of detection value was 0.2971 mg/mL and 0.5338 mg/mL, the limit of quantitation value was 0.9004 mg/mL and 1.6176 mg/mL, the range for both was 80% to 120%, and the specificity for both met the requirement. The Fourier Transform Infrared method has been successfully developed, applied, and validated for qualitative analysis and quantitative analysis of thiamphenicol in capsule dosage form.","PeriodicalId":21644,"journal":{"name":"Science and Technology Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44942456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-06DOI: 10.26554/sti.2023.8.3.422-428
Z. Rodzi, Ashiera Nadiha Hazri, Nurul Ain Syahirah Mohd Azri, Nurul Dania Farisha Sharul Rhmdan, Zati Aqmar Zaharudin, S. Uttunggadewa
This study investigates the barriers to household waste recycling in Seremban, Malaysia, using the Decision-Making Trial and Evaluation Laboratory (DEMATEL) analysis. The research questions aimed to identify and rank the most significant barriers to recycling and understand the causal relationships between them. The study found that limited access to recycling facilities and services and lack of motivation or incentive to recycle were the most significant causes of household waste recycling barriers in Seremban. Onthe other hand, lack of motivation or incentive to recycle and negative attitudes towards recycling, were identified as the most significant effects. The study’s findings have theoretical implications for waste management and sustainable development and offer practical implications for policymakers and waste management practitioners in developing effective waste management strategies and policies that can address these barriers. Furthermore, the study’s insights into the most significant barriers to household waste recycling can inform the design of recycling campaigns and educational programs to increase awareness and promote household waste recycling in Seremban. Overall, this study provides a valuable contribution to the field of waste management and sustainable development and offers insights into the challenges of promoting household waste recycling in urban areas.
{"title":"Uncovering Obstacles to Household Waste Recycling in Seremban, Malaysia through Decision-Making Trial and Evaluation Laboratory (DEMATEL) Analysis","authors":"Z. Rodzi, Ashiera Nadiha Hazri, Nurul Ain Syahirah Mohd Azri, Nurul Dania Farisha Sharul Rhmdan, Zati Aqmar Zaharudin, S. Uttunggadewa","doi":"10.26554/sti.2023.8.3.422-428","DOIUrl":"https://doi.org/10.26554/sti.2023.8.3.422-428","url":null,"abstract":"This study investigates the barriers to household waste recycling in Seremban, Malaysia, using the Decision-Making Trial and Evaluation Laboratory (DEMATEL) analysis. The research questions aimed to identify and rank the most significant barriers to recycling and understand the causal relationships between them. The study found that limited access to recycling facilities and services and lack of motivation or incentive to recycle were the most significant causes of household waste recycling barriers in Seremban. Onthe other hand, lack of motivation or incentive to recycle and negative attitudes towards recycling, were identified as the most significant effects. The study’s findings have theoretical implications for waste management and sustainable development and offer practical implications for policymakers and waste management practitioners in developing effective waste management strategies and policies that can address these barriers. Furthermore, the study’s insights into the most significant barriers to household waste recycling can inform the design of recycling campaigns and educational programs to increase awareness and promote household waste recycling in Seremban. Overall, this study provides a valuable contribution to the field of waste management and sustainable development and offers insights into the challenges of promoting household waste recycling in urban areas.","PeriodicalId":21644,"journal":{"name":"Science and Technology Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44888510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-06DOI: 10.26554/sti.2023.8.3.494-500
Amina Chidouh, Tarek Tahraoui, B. Barhouchi
Due to the high prevalence of micro-organisms resistant to conventional antimicrobials, the search for new antimicrobial drugs is underway, with nanoparticles being one of the options. This study reports for the first time the use of the coprecipitation method to synthesize europium (Eu) doped spinel manganese ferrites nanoparticles (MnEu0.1Fe1.9O4NPs). The purpose of this research is to determine the antimicrobial activity of MnEu0.1Fe1.9O4NPs. MnEu0.1Fe1.9O4NPs were analyzed using Fourier Transform Infrared Spectroscopy (FTIR), X Ray Diffraction (XRD), and Scanning Electron Microscopy (SEM) combined with Energy Dispersive X-Ray Analysis (EDX) to determine their structure, size, morphology and elemental compositions. The antimicrobial activity of synthesized nanoparticles was evaluated qualitatively using a diffusion disc on agar, followed by minimum inhibitory concentrations (MIC) determination. The findings show that all tested strains were adversely affected by the examined NPs, where E. coli exhibited the highest sensitivity to NPs, followed by S. aureus. The NPs displayed a moderate level of anti-candida action. MnEu0.1Fe1.9O4NPs could be exploited in biomedical usages.
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