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Trichoscopy of Discoid Lupus Erythematosus in the Black Scalp: A Literature Review 黑头皮盘状红斑狼疮的毛镜检查:文献综述
Q2 Medicine Pub Date : 2023-10-27 DOI: 10.1159/000534430
Thayane Batista Lemos, Rita Fernanda Cortez de Almeida, Sidney Frattini, Michela Starace, Daniel Fernandes Melo
Discoid lupus erythematosus (DLE) is the most common type of chronic cutaneous lupus erythematosus. It is more frequent in adult women, particularly black race. Scalp DLE has an earlier onset and a more severe clinical course in black patients compared to Caucasians. Nevertheless, studies on this population remain scarce. The aim of this study was to review the literature and summarize the most frequent trichoscopic findings of scalp DLE among patients with a higher phototype. The main trichoscopic findings of DLE on black scalp are interruption of the honeycomb pattern, reduction, or absence of pinpoint white dots, keratotic follicular plugs and peripilar casts, blue-gray dots in a speckled pattern, and large tortuous arboriform vessels. Knowledge of these and other changes enables an early diagnosis of these individuals, preventing cicatricial sequelae and reducing its impact on quality of life.
盘状红斑狼疮(DLE)是最常见的慢性皮肤红斑狼疮类型。它在成年女性中更为常见,尤其是黑人。与白种人相比,黑人患者的头皮DLE发病更早,临床病程更严重。然而,对这一群体的研究仍然很少。本研究的目的是回顾文献并总结在高光型患者中最常见的头皮DLE的毛发镜检查结果。黑色头皮DLE的主要毛镜表现为蜂窝状斑点中断,针状白点减少或消失,角化性毛囊塞和周围铸造,斑点状蓝灰色斑点,大的弯曲的树状血管。对这些和其他变化的了解有助于对这些个体进行早期诊断,预防瘢痕后遗症并减少其对生活质量的影响。
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引用次数: 0
Use of Oral Supplements and Topical Adjuvants for Isotretinoin-Associated Side Effects: A Narrative Review 使用口服补充剂和局部佐剂治疗异维甲酸相关副作用:叙述性回顾
Q2 Medicine Pub Date : 2023-10-20 DOI: 10.1159/000533963
Sophia Reyes-Hadsall, Teresa Ju, Jonette E. Keri
Acne is a chronic inflammatory disease of the pilosebaceous unit with a multifactorial etiology and is one of the most common conditions treated by dermatologists and primary care physicians. Within an extensive and evolving treatment landscape, oral isotretinoin has demonstrated efficacy for treatment of severe, recalcitrant acne. Several side effects of isotretinoin have been reported, including laboratory abnormalities, mucocutaneous, and musculoskeletal effects, which may reduce compliance and patient satisfaction with treatment. In this narrative review, we aim to review the efficacy and safety profile of oral supplements or topical adjuvant therapies in mitigating isotretinoin-associated mucocutaneous and musculoskeletal side effects. Oral supplements reviewed include omega-3 fatty acids, vitamin E, folic acid and vitamin B12, antihistamines, l-carnitine, biotin, and combined oral supplements. Topical adjuvants include a hyaluronic acid, biosaccharide gum-2, and glycerine gel-cream; a nongreasy, noncomedogenic, fragrance-free moisturizing cream; dexpanthenol; trichloroacetic acid; and a combination cream. Most of the supplements and topical adjuvants demonstrated efficacy with an adequate level of supporting evidence and no reported adverse events, indicating an adequate safety profile. Patients on isotretinoin may benefit from using oral supplements and topical adjuvants to minimize primarily mucocutaneous side effects, increase adherence to treatment, and thereby improve overall outcomes.
痤疮是皮脂腺单位的慢性炎症性疾病,具有多因素的病因,是皮肤科医生和初级保健医生治疗的最常见的疾病之一。在广泛和不断发展的治疗领域,口服异维甲酸已被证明对治疗严重的顽固性痤疮有效。异维甲酸的一些副作用已被报道,包括实验室异常,粘膜皮肤和肌肉骨骼的影响,这可能会降低依从性和患者对治疗的满意度。在这篇叙述性综述中,我们的目的是回顾口服补充剂或局部辅助治疗在减轻异维甲酸相关的粘膜和肌肉骨骼副作用方面的有效性和安全性。口服补充剂包括omega-3脂肪酸、维生素E、叶酸和维生素B12、抗组胺药、-肉毒碱、生物素和联合口服补充剂。局部佐剂包括透明质酸、生物糖胶-2和甘油凝胶霜;一种不油腻、不生粉刺、无香味的保湿霜;dexpanthenol;三氯乙酸;还有一款组合面霜。大多数补充剂和局部佐剂都有足够的证据证明其有效性,没有报告的不良事件,表明具有足够的安全性。服用异维甲酸的患者可能受益于口服补充剂和局部佐剂,以减少主要是粘膜皮肤的副作用,增加对治疗的依从性,从而改善总体结果。
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引用次数: 0
Calcipotriene/Betamethasone Dipropionate Foam as a Potential Safe and Effective Treatment of Nail Psoriasis 钙泊三烯/二丙酸倍他米松泡沫作为一种潜在安全有效的治疗指甲银屑病的方法
Q2 Medicine Pub Date : 2023-10-17 DOI: 10.1159/000533994
Alia Abbas, Sima Amin, Adaugo Sanyi, Tiffany Mayo, Boni Elewski
Background: Nail psoriasis is a common condition that affects quality of life in individuals with psoriasis and psoriatic arthritis. Topical treatments have been shown to be effective in treating nail bed disease but not as effective in treating nail matrix diseases, which often requires intralesional corticosteroids. Objectives: The objective of this open-label study was to evaluate the efficacy of combination calcipotriol/betamethasone dipropionate foam as a treatment for nail psoriasis including nail matrix disease. Method: We report three patients with moderate to severe nail psoriasis with involvement of all ten fingernails who applied study foam nightly for 6 months. Nails were assessed using the NAPSI score evaluating both nail bed and nail matrix disease. Results: NAPSI score improved including nail matrix disease in the majority of nails. No skin irritation or unexpected adverse events occurred. Conclusions: We conclude this foam combination product could be an effective and safe treatment for fingernail psoriasis and may provide better nail matrix penetration as evidenced by improvement in nail matrix score. Further studies are needed for additional evaluation.
背景:甲牛皮癣是影响牛皮癣和银屑病关节炎患者生活质量的常见疾病。局部治疗已被证明对治疗甲床疾病有效,但对治疗甲基质疾病不那么有效,这通常需要局部皮质类固醇。目的:这项开放标签研究的目的是评估钙三醇/二丙酸倍他米松泡沫联合治疗甲牛皮癣(包括甲基质病)的疗效。方法:我们报告了3例中度至重度指甲牛皮癣患者,所有十个指甲都受累,每晚应用研究泡沫6个月。采用NAPSI评分评估甲床和甲基质疾病。结果:NAPSI评分改善,包括大多数指甲基质疾病。无皮肤刺激或意外不良事件发生。结论:该泡沫组合产品可以有效、安全地治疗指甲型银屑病,并且可以提供更好的甲基质穿透,甲基质评分的提高证明了这一点。需要进一步的研究来进一步评价。
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引用次数: 0
Ungual Scabies: A Case Report and Review of Literature 双足疥疮一例报告及文献复习
Q2 Medicine Pub Date : 2023-10-11 DOI: 10.1159/000533881
Vishal Gaurav, Mehul Tyagi, Chander Grover, Shukla Das
Introduction: Nail unit infestation by scabies mites (ungual scabies) is uncommon. It usually presents with distal subungual lesions, leading to recurrent and persistent disease by acting as a reservoir of infection. Periungual involvement in scabies with nail loss is rare and may lead to severe nail damage. Case Presentation: We report a 14-year-old boy on chemotherapy for acute lymphocytic leukemia (ALL) who presented with extensive scaling and crusted plaques of scabies. Nail unit revealed periungual crusted plaques with paronychia and onychomadesis involving five digits. It was associated with partial to complete nail loss. Dermoscopy of periungual crusted plaques showed greyish-white scales with brown dots and globules. A sinuous burrow with a brown-triangular structure was visualized in the web space. KOH mount from skin scrapings showed the scabies mites. Treatment of scabies led to a marked improvement. Conclusion: Though ungual scabies is generally a benign disease, proximal periungual involvement with damage to nail matrix is possible, leading to nail loss. We review manifestations of nail unit scabies reported in literature. Treatment options used and outcomes are also analyzed. The importance of nail-directed therapy in preventing relapses of scabies cannot be undermined.
& lt; b> & lt; i>简介:& lt; / i> & lt; / b>甲单位感染疥螨(脚疥疮)是不常见的。它通常表现为远端跖下病变,作为感染的储存库,导致复发和持续的疾病。疥疮的甲周受累是罕见的,可能导致严重的甲损伤。& lt; b> & lt; i>案例表示:& lt; / i> & lt; / b>我们报告一个14岁的男孩在化疗急性淋巴细胞白血病(ALL)谁提出了广泛的鳞屑和结痂斑块疥疮。甲单位显示甲周结痂斑块伴甲骨旁和甲发育累及五指。它与部分到完全的指甲脱落有关。皮镜检查蹄骨周围结痂斑块显示灰白色鳞片,有棕色斑点和小球体。在网络空间中,一个具有棕色三角形结构的弯曲洞穴被可视化。皮肤刮擦的KOH检查显示疥螨。对疥疮的治疗有了明显的改善。& lt; b> & lt; i>结论:& lt; / i> & lt; / b>虽然足部疥疮通常是一种良性疾病,但近端足部周围的甲基质受损是可能的,导致甲丢失。我们回顾了文献报道的甲单位疥疮的表现。还分析了所使用的治疗方案和结果。指甲治疗在预防疥疮复发中的重要性不容忽视。
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引用次数: 0
Paclitaxel-Induced Periarticular Thenar Erythema with Onycholysis Syndrome 紫杉醇诱导的关节周围鱼际红斑伴溶甲综合征
Q2 Medicine Pub Date : 2023-10-11 DOI: 10.1159/000534118
Japnoor Kaur, Vishal Gaurav, Mehul Tyagi
Introduction: Periarticular thenar erythema with onycholysis (PATEO) syndrome is a rare subtype of hand-foot syndrome seen in patients undergoing taxane-based chemotherapy. It presents as erythematous to violaceous plaques on the dorsum of hands, feet, and around the Achilles tendon along with nail changes, particularly onycholysis. Case Presentation: A 39-year-old female on paclitaxel chemotherapy for stage IIIA (T3N2aM0) invasive ductal breast carcinoma, presented with mildly tender erythematous to violaceous plaques involving the dorsa of bilateral hands and feet, in the periarticular areas of the Achilles tendon, with facial involvement. All fingernails showed shortening, orange-red chromonychia, Beau’s lines, onychoschizia, and subungual debris. The toenail involvement was relatively less severe, with distal onycholysis being the predominant finding. The patient showed significant improvement in cutaneous lesions with topical steroid therapy and was advised cold water immersion during subsequent chemotherapy infusions. Discussion: A shorter interval between cycles and a higher cumulative number of cycles correlate with severity of dermatitis and nail involvement. Rarely, periocular and facial involvement can occur concurrently with PATEO syndrome. This case is being reported to increase awareness about this entity facilitating early diagnosis and treatment.
& lt; b> & lt; i>简介:& lt; / i> & lt; / b>关节周围鱼际红斑伴软骨溶解(PATEO)综合征是一种罕见的手足综合征亚型,见于接受紫杉烷类化疗的患者。它表现为手背、脚背和跟腱周围的红斑到紫色斑块,并伴有指甲变化,尤其是骨关节溶解。& lt; b> & lt; i>案例表示:& lt; / i> & lt; / b>39岁女性,因IIIA期(T3N2aM0)浸润性导管性乳腺癌接受紫杉醇化疗,表现为双侧手、足背、跟腱关节周围区域出现轻度嫩痛性红斑至紫色斑块,累及面部。所有指甲均呈缩短、橙红色色痕、博氏纹、甲裂和趾下碎片。趾甲受累相对较轻,主要表现为远端骨关节溶解。在局部类固醇治疗下,患者的皮肤病变得到了显著改善,在随后的化疗输注中建议冷水浸泡。& lt; b> & lt; i>讨论:& lt; / i> & lt; / b>较短的周期间隔和较高的周期累积次数与皮炎和指甲受累的严重程度相关。极少情况下,眼周和面部受累可同时发生博泰综合征。报告这一病例是为了提高对这一实体的认识,促进早期诊断和治疗。
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引用次数: 0
Electronic Nicotine Dispensing Systems Compared to Traditional Cigarettes in Hidradenitis Suppurativa: A Cross-Sectional Survey of Patient and Dermatologist Perceptions. 电子尼古丁分配系统与传统香烟在慢性支气管炎中的比较:患者和皮肤科医生认知的横断面调查
IF 1.4 Q3 DERMATOLOGY Pub Date : 2023-10-01 Epub Date: 2023-06-28 DOI: 10.1159/000531079
Sneha Poondru, Kourtney Scott, Julia M Riley

Background: Smoking cigarettes can have deleterious effects on hidradenitis suppurativa (HS) disease severity, but little is known about the relationship between vaping electronic nicotine delivery systems (ENDS) and HS severity.

Objectives: The aim of this study was to determine the rate of ENDS use in those with HS and the perceptions of HS participants and dermatologists on the relationship between vaping and HS.

Methods: Two separate cross-sectional, anonymous, multiple-choice questionnaires were administered. One questionnaire was distributed to those with HS recruited via online HS-related forums. Inclusion criteria were diagnosis of HS, age 18 and over, and residence in USA. The other questionnaire was distributed to currently practicing, board-certified dermatologists recruited via an email listserv.

Results: Overall, 302 participants with HS completed the questionnaire. Fifty-six participants (18.5%) smoke cigarettes and 41 participants (13.6%) vape ENDS. One-third of ENDS users (14/41) switched from cigarettes to ENDS after learning of their HS diagnosis, of which 78.6% (11/14) believed that the switch decreased the severity and/or frequency of their HS flares. Fifty dermatologists completed the questionnaire, of whom over half (54%, 27/50) were unsure about the relationship between vaping and HS severity.

Conclusions: As cigarette smoking and HS are closely linked, the use of ENDS in HS warrants further study.

背景:吸烟会对化脓性手足口炎(HS)疾病的严重程度产生有害影响,但人们对电子尼古丁输送系统(ENDS)与HS严重程度之间的关系知之甚少。目的:本研究的目的是确定HS患者的ENDS使用率,以及HS参与者和皮肤科医生对电子烟与HS之间关系的看法。方法:采用两份独立的横断面、匿名、多项选择问卷。通过与HS相关的在线论坛向招募的HS患者分发了一份问卷。纳入标准为HS诊断、18岁及以上、居住在美国。另一份问卷通过电子邮件列表服务分发给目前执业的、经委员会认证的皮肤科医生。结果:总体而言,302名HS参与者完成了问卷调查。56名参与者(18.5%)吸烟,41名参与者(13.6%)吸电子烟。三分之一的ENDS使用者(14/41)在得知自己的HS诊断后从香烟转向ENDS,其中78.6%(11/14)认为这种转变降低了他们HS发作的严重程度和/或频率。50名皮肤科医生完成了问卷调查,其中超过一半(54%,27/50)不确定电子烟与HS严重程度之间的关系。结论:吸烟与HS密切相关,ENDS在HS中的应用值得进一步研究。
{"title":"Electronic Nicotine Dispensing Systems Compared to Traditional Cigarettes in Hidradenitis Suppurativa: A Cross-Sectional Survey of Patient and Dermatologist Perceptions.","authors":"Sneha Poondru, Kourtney Scott, Julia M Riley","doi":"10.1159/000531079","DOIUrl":"10.1159/000531079","url":null,"abstract":"<p><strong>Background: </strong>Smoking cigarettes can have deleterious effects on hidradenitis suppurativa (HS) disease severity, but little is known about the relationship between vaping electronic nicotine delivery systems (ENDS) and HS severity.</p><p><strong>Objectives: </strong>The aim of this study was to determine the rate of ENDS use in those with HS and the perceptions of HS participants and dermatologists on the relationship between vaping and HS.</p><p><strong>Methods: </strong>Two separate cross-sectional, anonymous, multiple-choice questionnaires were administered. One questionnaire was distributed to those with HS recruited via online HS-related forums. Inclusion criteria were diagnosis of HS, age 18 and over, and residence in USA. The other questionnaire was distributed to currently practicing, board-certified dermatologists recruited via an email listserv.</p><p><strong>Results: </strong>Overall, 302 participants with HS completed the questionnaire. Fifty-six participants (18.5%) smoke cigarettes and 41 participants (13.6%) vape ENDS. One-third of ENDS users (14/41) switched from cigarettes to ENDS after learning of their HS diagnosis, of which 78.6% (11/14) believed that the switch decreased the severity and/or frequency of their HS flares. Fifty dermatologists completed the questionnaire, of whom over half (54%, 27/50) were unsure about the relationship between vaping and HS severity.</p><p><strong>Conclusions: </strong>As cigarette smoking and HS are closely linked, the use of ENDS in HS warrants further study.</p>","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46456967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pigmented Onychomatricoma Presenting as Pachymelanonychia Striata: A Case Report and Review of Literature. 色素沉着的Onychomatroma表现为条纹状多膜性:一例病例报告和文献复习。
IF 1.4 Q3 DERMATOLOGY Pub Date : 2023-10-01 Epub Date: 2023-06-21 DOI: 10.1159/000529820
Chander Grover, Vishal Gaurav, Sonal Sharma, Surabhi Sinha

Introduction: Onychomatricoma is a fibroepithelial tumor derived from the nail matrix and onychodermis. Many clinical and histological variants have been described. Pigmented onychomatricoma is a rare variant which presents as longitudinal pachymelanonychia.

Case presentation: We report the details of a 41-year-old female who presented with blackening and thickening involving more than half of the left middle fingernail for the past 10 years. Dorsal plate onychoscopy revealed longitudinal parallel white, gray, and black bands, while onychoscopy of the distal free edge demonstrated a thickened nail plate with "wood worm" cavities. The histopathological examination of the excised tumor revealed a pigmented onychomatricoma.

Conclusions: Onychomatricoma is one of the nail tumors presenting as pachyonychia striata apart from onychocytic matricoma and onychocytic carcinoma. A pigmented onychomatricoma may closely mimic fungal melanonychia, pigmented onychopapilloma, pigmented ungual Bowen's disease, and ungual melanoma. Noninvasive techniques like onychoscopy and imaging studies like ultrasonography and magnetic resonance imaging are helpful in differentiating it from pigmented ungual Bowen's disease and ungual melanoma, even though diagnostic confirmation requires an excisional biopsy.

引言:甲癣是一种来源于指甲基质和甲真皮层的纤维上皮肿瘤。已经描述了许多临床和组织学变异。色素性甲基质瘤是一种罕见的变异,表现为纵向厚甲。病例介绍:我们报告了一名41岁女性的详细情况,她在过去10年中出现了超过一半的左中指指甲变黑和增厚。甲片背面甲片显示纵向平行的白色、灰色和黑色条纹,而远端自由边缘甲片显示甲片增厚,有“木虫”腔。切除肿瘤的组织病理学检查显示有色素性甲母细胞瘤。结论:除甲基质瘤和甲细胞癌外,甲细胞瘤是表现为条纹状厚甲的指甲肿瘤之一。色素性甲基质瘤可能与真菌性黑指甲炎、色素性甲乳头瘤、色素性蹄鲍恩病和蹄黑色素瘤非常相似。尽管诊断确认需要切除活组织检查,但非侵入性技术,如甲镜检查以及超声和磁共振成像等成像研究,有助于将其与色素性蹄鲍恩病和蹄黑色素瘤区分开来。
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引用次数: 0
Normal Trichoscopic Findings after Hair Transplantation in Androgenetic Alopecia: A Prospective Case Series. 雄激素性脱发毛发移植后的正常毛发镜检查结果:一个前瞻性病例系列
IF 1.4 Q3 DERMATOLOGY Pub Date : 2023-10-01 Epub Date: 2023-07-20 DOI: 10.1159/000531220
Leticia Arsie Contin, José Benito Santos Júnior, Carla Jorge Machado, Vanessa Barreto Rocha

Background: Trichoscopy can be very useful for evaluation for hair transplantation (HT), helping rule out simulators of androgenetic alopecia (AGA). There are only a few reports about normal trichoscopic findings after HT.

Objective: The aim of this study was to evaluate donor and recipient area trichoscopy after FUE in HT without complications in AGA patients.

Method: A prospective study was carried out with 10 patients, for 24 weeks, with photographic follow-up, using FotoFinder®. Patients were evaluated from week 1 (w1) to week 8 weekly, then, at week 12 and week 24 post-HT.

Results: Main results were perifollicular crusts, donor area erythema, recipient area erythema, perifollicular erythema, white circles, perifollicular whitish halos, repilation black dots, dystrophic hairs, folliculitis, yellow dots. We discussed the meaning of each of these findings in the period in which they occurred.

Conclusion: Normal trichoscopic findings in post-transplant patients have not been well established yet. Our findings are an attempt to define a normal pattern. Future studies with a longer follow-up may be necessary to corroborate these results.

背景:毛发镜检查对毛发移植(HT)的评估非常有用,有助于排除雄激素性脱发(AGA)的模拟物。关于HT后正常的毛发镜检查结果的报道很少。目的:本研究的目的是评估FUE后HT患者的供体和受体区域毛发镜检查,而AGA患者没有并发症。方法:使用FotoFinder®对10名患者进行了为期24周的前瞻性研究,并进行了摄影随访。从第1周(w1)到第8周,然后在HT后第12周和第24周对患者进行评估。结果:主要结果为毛囊周围结皮、供体区红斑、受体区红斑、毛囊周围红斑、白圈、毛囊周围白色光晕、扭曲黑点、营养不良毛发、毛囊炎、黄点。我们讨论了这些发现在发生时期的意义。结论:移植后患者的正常毛发检查结果尚未得到很好的证实。我们的发现试图定义一种正常的模式。为了证实这些结果,未来可能需要更长时间的随访研究。
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引用次数: 0
Trichoscopic Patterns and Confocal Microscopy Features of Chemotherapy-Induced Alopecia. 化疗诱发脱发的毛镜模式和共聚焦显微镜特征。
IF 1.4 Q3 DERMATOLOGY Pub Date : 2023-10-01 Epub Date: 2023-07-12 DOI: 10.1159/000531183
Maria Carmela Annunziata, Antonella Tosti, Davide Fattore, Luca Potestio, Austin John Maddy, Gabriella Fabbrocini

Introduction: Chemotherapy-induced alopecia (CIA) can seriously affect the quality of life of cancer patients. Trichoscopic patterns and confocal microscopy (RCM) features of CIA have been scarcely studied. This study aimed to investigate the dermoscopic and RCM features of CIA in 19 females and 5 males, with CIA due to current or recent chemotherapy.

Methods: Patients with CIA and current or recent (within 2 months) history of chemotherapy treatment were enrolled. After clinical examination, standard pictures were taken by digital camera (SLR Canon PowerShot G10) and trichoscopic images were captured by the Handyscope device (20x). Images of RCM were acquired by VivaScope 3000 with the VivaStack option. The trichoscopic and confocal images were acquired by three independent observers after central parting on three areas: vertex, middle, and frontal scalp.

Results: A total of 24 patients were enrolled. CIA has features of anagen effluvium at trichoscopy but with low frequency of yellow dots and prominence of black dots. The simultaneous presence of pseudo-monilethrix and black dots at trichoscopy confirms the hypothesis that chemotherapy insults the hair follicle intermittently. At RCM, the presence of abnormal hair shaft morphology highlights that the insults affect hair shaft production.

Conclusion: These are the first data in this field, so further studies with a higher number of patients analyzed are needed to confirm these findings.

简介:化疗性脱发(CIA)严重影响癌症患者的生活质量。CIA的毛状结构和共聚焦显微镜(RCM)特征研究较少。本研究旨在调查19名女性和5名男性CIA的皮肤镜和RCM特征,CIA是由当前或最近的化疗引起的。方法:选择有CIA和目前或最近(2个月内)化疗史的患者。临床检查后,用数码相机(SLR Canon PowerShot G10)拍摄标准照片,用Handyscope设备(20x)拍摄毛发镜图像。RCM的图像由VivaScope 3000使用VivaStack选项采集。三个独立的观察者在三个区域(顶点、中间和正面头皮)进行中心分割后获得了三角镜和共焦图像。结果:共有24名患者入选。毛镜下CIA具有生长期恶臭的特征,但黄点出现频率低,黑点突出。在毛发镜检查中同时存在假念珠和黑点,这证实了化疗间歇性损伤毛囊的假设。在RCM,异常发干形态的存在突出表明,损伤会影响发干的产生。结论:这些是该领域的第一批数据,因此需要对更多的患者进行进一步的研究来证实这些发现。
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引用次数: 0
A Bibliometric Analysis of the Top 100 Highly Cited Onychomycosis Publications Using SCOPUS Database (1972-2022). 利用SCOPUS数据库对甲真菌病高引用100种出版物的文献计量分析(1972–2022)
IF 1.4 Q3 DERMATOLOGY Pub Date : 2023-10-01 Epub Date: 2023-07-12 DOI: 10.1159/000531184
Samantha Jo Albucker, Shari R Lipner

Introduction: Onychomycosis represents half of nail disorders seen in clinical practice. Despite its high prevalence, a bibliometric analysis has not been performed. We aimed to identify the top 100 highly cited onychomycosis publications over the last 50 years to better understand research trends.

Methods: SCOPUS was searched for onychomycosis publications, using "onychomycosis" and "nail fungus" 1/1/1972-12/31/22 on 3/25/23. Top 100 highly cited publications were recorded and ranked by total citation count.

Results: Total citation count was 13,456, with the top 10 articles with highest citation count/year having average 28.7 citations/year. Most articles were published in high IF journals. From 1982 to 2011 (no treatment articles - 1972-1981), there was an 8.6% increase in articles discussing treatment. Overall, 42% of first authors were female.

Conclusion: We found an overall increase in articles discussing onychomycosis therapies over time, with the majority published in high IF journals. We also found a relatively greater percentage of female first authors compared to studies on other dermatologic topics. While total citation count remains a widely used metric of impact in bibliometric studies, average citation count/year may be a better measure of impact and should be considered in future studies.

引言:甲真菌病是临床上常见的指甲疾病的一半。尽管其流行率很高,但尚未进行文献计量学分析。我们旨在确定过去50年中被高度引用的甲真菌病出版物的前100名,以更好地了解研究趋势。方法:采用SCOPUS检索甲真菌病文献,检索时间为1972-12/31/22年1月1日,检索日期为3/25/25。记录了前100种被高度引用的出版物,并按引用总数进行了排名。结果:总引用次数为13456次,其中引用次数最高的前10篇文章平均每年被引用28.7次。大多数文章发表在国际单项体育联合会的高级期刊上。从1982年到2011年(没有治疗文章——1972年到1981年),讨论治疗的文章增加了8.6%。总体而言,42%的第一作者是女性。结论:随着时间的推移,我们发现讨论甲真菌病治疗的文章总体上有所增加,其中大多数发表在高IF期刊上。我们还发现,与其他皮肤科主题的研究相比,女性第一作者的比例相对更高。虽然总引用次数仍然是文献计量学研究中广泛使用的影响指标,但平均引用次数/年可能是衡量影响的更好指标,应在未来的研究中予以考虑。
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引用次数: 0
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Skin Appendage Disorders
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