Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-378-401
E. V. Ivanova, I. Surova, M. Nikishina, L. Mukhtorov, I. Shahkeldyan, Yurij Atroshchenko
Background. Pyridines are one of the most common heterocycles, the derivatives of which are widely used in pharmaceuticals, agrochemistry, and also in the production of new materials. Therefore, a comprehensive study of the chemical behavior of various pyridine derivatives will continue to be an urgent task of organic chemistry. This literature review is devoted to the systematization and analysis of the chemical properties of pyridine nitro derivatives, starting from the first half of the 20th century and up to the present. The paper considers both reactions proceeding through the nitro group (reduction under the action of various chemical agents, substitution, condensation) and reactions through the pyridine cycle. The main areas of application of nitropyridines are also shown. Purpose. Generalize and systematize the main types of reactions characteristic of nitropyridines, show the features of their chemical properties associated with the transformation of the nitro group, its effect on the mobility of substituents in the pyridine ring, as well as on the activity of the heterocycle as a whole. Materials and methods. To achieve the goal of the study, a review of the scientific literature was made on the main types of chemical reactions characteristic of pyridine nitro derivatives and the most significant areas of their application. Results. This paper summarizes the results of experimental studies on the chemical properties and application of nitropyridines from the beginning of the last century to the present. Conclusion. Thus, as a result of the analysis of sources devoted to the chemical properties and application of nitropyridines, a brief literature review was compiled, including the main types of reactions characteristic of the compounds under study, and their main areas of application were identified.
{"title":"CHEMICAL PROPERTIES AND APPLICATIONS OF NITROPYRIDINES","authors":"E. V. Ivanova, I. Surova, M. Nikishina, L. Mukhtorov, I. Shahkeldyan, Yurij Atroshchenko","doi":"10.12731/2658-6649-2023-15-1-378-401","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-378-401","url":null,"abstract":"Background. Pyridines are one of the most common heterocycles, the derivatives of which are widely used in pharmaceuticals, agrochemistry, and also in the production of new materials. Therefore, a comprehensive study of the chemical behavior of various pyridine derivatives will continue to be an urgent task of organic chemistry. This literature review is devoted to the systematization and analysis of the chemical properties of pyridine nitro derivatives, starting from the first half of the 20th century and up to the present. The paper considers both reactions proceeding through the nitro group (reduction under the action of various chemical agents, substitution, condensation) and reactions through the pyridine cycle. The main areas of application of nitropyridines are also shown. \u0000Purpose. Generalize and systematize the main types of reactions characteristic of nitropyridines, show the features of their chemical properties associated with the transformation of the nitro group, its effect on the mobility of substituents in the pyridine ring, as well as on the activity of the heterocycle as a whole. \u0000Materials and methods. To achieve the goal of the study, a review of the scientific literature was made on the main types of chemical reactions characteristic of pyridine nitro derivatives and the most significant areas of their application. \u0000Results. This paper summarizes the results of experimental studies on the chemical properties and application of nitropyridines from the beginning of the last century to the present. \u0000Conclusion. Thus, as a result of the analysis of sources devoted to the chemical properties and application of nitropyridines, a brief literature review was compiled, including the main types of reactions characteristic of the compounds under study, and their main areas of application were identified.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47200861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-435-453
V. Shestak, A. Tsyplakova, I. Kholikov
Background. The assessed reproduction technologies (ART) often involve a range of controversial ethical and legal issues that are inspiring for research. Purpose. Comprehensive study on ways to use certain types of technologies. Materials. This paper provides with research of a legal framework of the ART based on the legislation of 13 Muslim countries: Oman, Saudi Arabia, Bahrain, Morocco, Jordan, the UAE, Malaysia, Iran, Lebanon, Egypt, Algeria, Tunisia and Turkey. Results. Due to a range of religious, ethical, legal and social reasons access to the ART was prohibited, but in recent decades mujtahids and fakihs have come to conclusion that for the sake of national prosperity and sustainable development of the ummah medically assisted reproduction may be permissible under certain conditions and must be regulated by laws and correspond to fatwas. The limits of usage of certain technologies have common tendency in gulf countries and the Northern Africa. Nevertheless, some other Muslim countries (e.g., Iran and Malaysia) address this issue in a more detailed and open-minded way. Conclusion. Although there’re legal mechanisms and tools for a broader interpretation and a wider interpretation despite critical opinion of theologies and restricted nature of so-called «gates of al-ijtihad», because they are based on established years ago institutes an, in fact, don’t contradict the foundations of Qur’an and Sunnah. However, features of Muslim law remain.
{"title":"LEGAL SITUATION REGARDING ASSESSED REPRODUCTION TECHNOLOGIES IN MUSLIM COUNTRIES","authors":"V. Shestak, A. Tsyplakova, I. Kholikov","doi":"10.12731/2658-6649-2023-15-1-435-453","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-435-453","url":null,"abstract":"Background. The assessed reproduction technologies (ART) often involve a range of controversial ethical and legal issues that are inspiring for research. \u0000Purpose. Comprehensive study on ways to use certain types of technologies. \u0000Materials. This paper provides with research of a legal framework of the ART based on the legislation of 13 Muslim countries: Oman, Saudi Arabia, Bahrain, Morocco, Jordan, the UAE, Malaysia, Iran, Lebanon, Egypt, Algeria, Tunisia and Turkey. \u0000Results. Due to a range of religious, ethical, legal and social reasons access to the ART was prohibited, but in recent decades mujtahids and fakihs have come to conclusion that for the sake of national prosperity and sustainable development of the ummah medically assisted reproduction may be permissible under certain conditions and must be regulated by laws and correspond to fatwas. The limits of usage of certain technologies have common tendency in gulf countries and the Northern Africa. Nevertheless, some other Muslim countries (e.g., Iran and Malaysia) address this issue in a more detailed and open-minded way. \u0000Conclusion. Although there’re legal mechanisms and tools for a broader interpretation and a wider interpretation despite critical opinion of theologies and restricted nature of so-called «gates of al-ijtihad», because they are based on established years ago institutes an, in fact, don’t contradict the foundations of Qur’an and Sunnah. However, features of Muslim law remain.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66376178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-327-345
Roman A. Yaskevich, Olga L. Moskalenko
Purpose. To study the features of affective disorders in men with comorbid chronic coronary heart disease with metabolic syndrome.
Materials and methods. The study was performed with the participation of 115 male patients diagnosed with chronic coronary heart disease. Metabolic syndrome verification was carried out using the clinical recommendations of the All-Russian Scientific Society of Cardiology (2009). Identification of the presence of anxiety-depressive states and assessment of their severity was carried out using The Hospital Anxiety and Depression scale.
Results. The study showed that among men with chronic coronary heart disease who have metabolic syndrome, the median averaged anxiety score on the Hospital Anxiety and Depression scale was significantly higher (p=0,041) compared to those without metabolic syndrome. In 17,6% of the examined patients with a combination of chronic coronary heart disease and metabolic syndrome, elevated levels of anxiety were detected. Anxiety disorders of a subclinically pronounced nature were found in 13,7% of the surveyed in this group, and clinically pronounced in 3,9%. Elevated levels of depression were detected in 17,6% of the examined patients with metabolic syndrome. At the same time, depressive disorders of both subclinically expressed and clinically expressed nature were detected with the same frequency: 7,8% vs 7,8%.
Conclusion. Among patients with chronic coronary heart disease with a comorbid course with metabolic syndrome, the number of people with clinically pronounced anxiety and depression was higher compared to those without metabolic syndrome. In men with chronic coronary heart disease in combination with metabolic syndrome with both increased levels of anxiety and increased levels of depression, 3- and 4-component clusters of metabolic syndrome, including arterial hypertension, abdominal obesity and various dyslipidemias, were more often detected.
目的。探讨男性慢性冠心病伴代谢综合征患者情感性障碍的特点。
材料和方法。这项研究是在115名诊断为慢性冠心病的男性患者的参与下进行的。代谢综合征验证采用全俄科学心脏病学会(2009)的临床建议进行。使用医院焦虑抑郁量表(the Hospital Anxiety and Depression scale)识别焦虑抑郁状态的存在并评估其严重程度。
结果。研究表明，在患有代谢综合征的慢性冠心病患者中，医院焦虑和抑郁量表的平均焦虑得分中位数明显高于没有代谢综合征的患者(p=0,041)。在17.6%患有慢性冠心病和代谢综合征的患者中，检测到焦虑水平升高。在这组被调查的人中，有13.7%的人有亚临床表现的焦虑障碍，有3.9%的人有临床表现。在接受检查的代谢综合征患者中，有17.6%的人发现抑郁水平升高。同时，亚临床表达性和临床表达性抑郁症的检出率相同，分别为7.8%和7.8%。
结论。在伴有代谢综合征的慢性冠心病患者中，与没有代谢综合征的患者相比，临床表现出焦虑和抑郁的人数更高。在慢性冠心病合并代谢综合征并焦虑和抑郁水平增加的男性中，代谢综合征的3-和4-组分簇，包括动脉高血压、腹部肥胖和各种血脂异常，更常被检测到。
{"title":"AFFECTIVE DISORDERS IN MEN WITH ARTERIAL HYPERTENSION IN COMBINATION WITH METABOLIC SYNDROME","authors":"Roman A. Yaskevich, Olga L. Moskalenko","doi":"10.12731/2658-6649-2023-15-1-327-345","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-327-345","url":null,"abstract":"Purpose. To study the features of affective disorders in men with comorbid chronic coronary heart disease with metabolic syndrome.
 Materials and methods. The study was performed with the participation of 115 male patients diagnosed with chronic coronary heart disease. Metabolic syndrome verification was carried out using the clinical recommendations of the All-Russian Scientific Society of Cardiology (2009). Identification of the presence of anxiety-depressive states and assessment of their severity was carried out using The Hospital Anxiety and Depression scale.
 Results. The study showed that among men with chronic coronary heart disease who have metabolic syndrome, the median averaged anxiety score on the Hospital Anxiety and Depression scale was significantly higher (p=0,041) compared to those without metabolic syndrome. In 17,6% of the examined patients with a combination of chronic coronary heart disease and metabolic syndrome, elevated levels of anxiety were detected. Anxiety disorders of a subclinically pronounced nature were found in 13,7% of the surveyed in this group, and clinically pronounced in 3,9%. Elevated levels of depression were detected in 17,6% of the examined patients with metabolic syndrome. At the same time, depressive disorders of both subclinically expressed and clinically expressed nature were detected with the same frequency: 7,8% vs 7,8%.
 Conclusion. Among patients with chronic coronary heart disease with a comorbid course with metabolic syndrome, the number of people with clinically pronounced anxiety and depression was higher compared to those without metabolic syndrome. In men with chronic coronary heart disease in combination with metabolic syndrome with both increased levels of anxiety and increased levels of depression, 3- and 4-component clusters of metabolic syndrome, including arterial hypertension, abdominal obesity and various dyslipidemias, were more often detected.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":"204 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135827355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-346-377
O. Gradov, M. Gradova, V. Kochervinskii
Physical and chemical criteria of biocompatibility of the active polymer implants and stimuli-responsive scaffolds are considered. From the standpoint of the surface physics and controlled wetting, the possibilities of dynamic control of biocompatibility and adaptive changes in the implant properties in response to the signal from the surrounding tissues are considered. The basic properties of the active biocompatible and biomimetic implantable materials, which distinguish them from the passive implants, are summarized. The latter include: electrophysical and electrophysiological membrane biocompatibility (up to the analogy with biomembranes – the so-called Fendler’s “membrane mimetics”); excitability, that is, the ability to qualitatively change their state in response to the external stimulus; compatibility of the matching parameters and impedances of biomembranes and active implantable materials; the presence of the main types of the energy conversion characteristic of biomembranes (chemiosmotic, electrochemical, electromechanical, etc.); the ability to transport and release pharmaceuticals consistent with the parameters of the cellular microenvironment and regulated by its state. Due to the qualitative change in the biomedical aim of such implants (from replacing the natural function to its regeneration and maintenance), there is a possibility of implementing various new biologically relevant functions using these materials, such as the ability to sensing and actuation, based on their reactivity and signal / energy conversion capacity. Of particular interest is the adaptive realization of the above functions in a growing and developing organism during its ontogenesis.
{"title":"BIOCOMPATIBLE BIOMIMETIC POLYMER STRUCTURES WITH AN ACTIVE RESPONSE FOR IMPLANTOLOGY AND REGENERATIVE MEDICINE PART I: BASIC PRINCIPLES OF THE ACTIVE IMPLANT’S BIOCOMPATIBILITY","authors":"O. Gradov, M. Gradova, V. Kochervinskii","doi":"10.12731/2658-6649-2023-15-1-346-377","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-346-377","url":null,"abstract":"Physical and chemical criteria of biocompatibility of the active polymer implants and stimuli-responsive scaffolds are considered. From the standpoint of the surface physics and controlled wetting, the possibilities of dynamic control of biocompatibility and adaptive changes in the implant properties in response to the signal from the surrounding tissues are considered. The basic properties of the active biocompatible and biomimetic implantable materials, which distinguish them from the passive implants, are summarized. The latter include: electrophysical and electrophysiological membrane biocompatibility (up to the analogy with biomembranes – the so-called Fendler’s “membrane mimetics”); excitability, that is, the ability to qualitatively change their state in response to the external stimulus; compatibility of the matching parameters and impedances of biomembranes and active implantable materials; the presence of the main types of the energy conversion characteristic of biomembranes (chemiosmotic, electrochemical, electromechanical, etc.); the ability to transport and release pharmaceuticals consistent with the parameters of the cellular microenvironment and regulated by its state. Due to the qualitative change in the biomedical aim of such implants (from replacing the natural function to its regeneration and maintenance), there is a possibility of implementing various new biologically relevant functions using these materials, such as the ability to sensing and actuation, based on their reactivity and signal / energy conversion capacity. Of particular interest is the adaptive realization of the above functions in a growing and developing organism during its ontogenesis.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46794779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-100-122
V. Kobechinskaya, O. Yarosh, Valery L. Apostolov
We present results of studies carried out from 2007 to 2020 on the assessment of the emission of the main greenhouse gases: carbon dioxide, carbon monoxide, methane, nitrous oxide, mono- and nitrogen dioxide, emitted during top and bottom fires in the forests of the Republic of Crimea. The aim of the work was to monitor greenhouse gas emissions as a result of fires according to ground-based studies in the forests of the peninsula. Materials and methods. The objects of study were uneven-aged burnt forests of pine plantations and oak forests in the foothill zone (Simferopol forestry), as well as pine and oak forests of the reserve located on the southern macroslope of the Crimean Mountains. The weight indicators of carbon emissions from fires for forest stand, undergrowth, undergrowth and litter are calculated taking into account conversion factors. Results. The total emissions of greenhouse gases from fires of different intensities in the foothill zone during this period reached 1575.6 t in (9.87 t/ha), and the contribution of carbon dioxide to the total volume was 6.1 t/ha. In the nature reserve, the total emissions were 23227.8 t in (20.98 t/ha) and 12.8 t/ha for carbon dioxide. These higher values are due to greater age, density and stock of the forest stand. The contributions of various greenhouse gases to the total emissions were: 61.2% for carbon dioxide, 28.5% for nitrogen dioxide, 8.5% for carbon monoxide, and less than 1.8% for methane and nitrous oxide in total. Conclusions. The method used in this study for calculating greenhouse gas emissions released during fire impact on forest ecosystems can be considered as a good toolkit for a detailed assessment of the amount of greenhouse gas emissions generated during fires of various intensities.
{"title":"ASSESSMENT OF GREENHOUSE GAS EMISSIONS IN CRIMEAN FORESTS UNDER THE INFLUENCE OF CROWN AND SURFACE FIRES","authors":"V. Kobechinskaya, O. Yarosh, Valery L. Apostolov","doi":"10.12731/2658-6649-2023-15-1-100-122","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-100-122","url":null,"abstract":"We present results of studies carried out from 2007 to 2020 on the assessment of the emission of the main greenhouse gases: carbon dioxide, carbon monoxide, methane, nitrous oxide, mono- and nitrogen dioxide, emitted during top and bottom fires in the forests of the Republic of Crimea. The aim of the work was to monitor greenhouse gas emissions as a result of fires according to ground-based studies in the forests of the peninsula. Materials and methods. The objects of study were uneven-aged burnt forests of pine plantations and oak forests in the foothill zone (Simferopol forestry), as well as pine and oak forests of the reserve located on the southern macroslope of the Crimean Mountains. The weight indicators of carbon emissions from fires for forest stand, undergrowth, undergrowth and litter are calculated taking into account conversion factors. Results. The total emissions of greenhouse gases from fires of different intensities in the foothill zone during this period reached 1575.6 t in (9.87 t/ha), and the contribution of carbon dioxide to the total volume was 6.1 t/ha. In the nature reserve, the total emissions were 23227.8 t in (20.98 t/ha) and 12.8 t/ha for carbon dioxide. These higher values are due to greater age, density and stock of the forest stand. The contributions of various greenhouse gases to the total emissions were: 61.2% for carbon dioxide, 28.5% for nitrogen dioxide, 8.5% for carbon monoxide, and less than 1.8% for methane and nitrous oxide in total. Conclusions. The method used in this study for calculating greenhouse gas emissions released during fire impact on forest ecosystems can be considered as a good toolkit for a detailed assessment of the amount of greenhouse gas emissions generated during fires of various intensities.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47480235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-77-99
K. Alimjanova, Mamura S. Rajabova
As a result of flora-systematic studies of the Akdarya reservoir, 71 species and varieties (63 species, 16 variations, 1 form) were identified, which belong to 4 departments, 10 orders, 14 families, 24 genera. The species composition is dominated by diatoms (Bacillariophyta), consisting of 56 species of varieties, followed by detached green (Cyanophyta) - 9 (8 species, 1 form), yellowish (Xanthophyta) - 4, green (Chlorophyta) - 2 species of algae. Hormogoniophyceae, Pennatae and Heterotrycho phyceae are the most diverse classes, representing 65 species and varieties (91.54%), consisting of 6 families, generalized by 62 different species (87.95%), and 7 genera, generalized by 53 (74, 64%) species and varieties. The flora-systematic analysis shows that the species composition of the Akdarya Reservoir’s algophore has a peculiar feature, where the data obtained in the Far East can be used in the study of the ecosystem of the Akdarya Reservoir, as biodiversity of primary producers. Background. The reservoir plays a major role in the formation of ecosystems of certain geographical areas. The comprehensive study of biodiversity in a reservoir makes it possible to study and monitor environmental and biological changes in environmental factors. For this purpose, a preliminary inventory of the state of the aquatic environment and its organisms is carried out. In this regard, the objective of our research is the taxonomic analysis of the Akdarya Reservoir’s algophore. Materials and Methods. In 2014-2022 from Akdarya reservoir-More than 150 alhologic samples have been collected and processed according to the generally accepted methods of alhology and hydrobiology [5, 6]. In the laboratory, preparations were prepared from algological samples, species compositions of algae were identified by determinants and frequency of occurrence in one lens field of view was determined. The experiments were carried out using a Carl Zeiss type light microscope, eyepiece +7 micrometer, and dyes. Species composition of algae, systematics and their taxonomy have been identified with the help of the determinant [4-11, 16] and the monograph [12, 17, 18]. The chemical composition of water is analyzed by the data of UzGMNII (Uzbek Hydrometeorological Research Institute). Results. Based on taxonomic analysis, 71 species and varieties of algae (63 species, 16 variations and 2 shapes) were identified in alhologic samples from the Akdarya reservoir. They belong to 4 divisions (Cyanophyta, Bacillariophyta, Xanthophyta, Chlorophyta), 8 classes, 10 orders, 14 families and 23 genera, which are given in table 1.2. Conclusion. The Akdarya reservoir in the middle of the Zarafshan River has a large amount of suspended substances and relatively high mineralization. This factor favourably influences the development, formation and intensive distribution of the algae division of Bacillariophyta (56), Cyanophyta (9), Xantophyta (4), Chlorophyta (2) in the ecosystem of the Akdarya reservoir. The
{"title":"TAXONOMIC ANALYSIS OF THE ALGOFLORA OF THE AKDARYA RESERVOIR IN THE MIDDLE REACHES OF THE ZARAFSHAN RIVER","authors":"K. Alimjanova, Mamura S. Rajabova","doi":"10.12731/2658-6649-2023-15-1-77-99","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-77-99","url":null,"abstract":"As a result of flora-systematic studies of the Akdarya reservoir, 71 species and varieties (63 species, 16 variations, 1 form) were identified, which belong to 4 departments, 10 orders, 14 families, 24 genera. The species composition is dominated by diatoms (Bacillariophyta), consisting of 56 species of varieties, followed by detached green (Cyanophyta) - 9 (8 species, 1 form), yellowish (Xanthophyta) - 4, green (Chlorophyta) - 2 species of algae. Hormogoniophyceae, Pennatae and Heterotrycho phyceae are the most diverse classes, representing 65 species and varieties (91.54%), consisting of 6 families, generalized by 62 different species (87.95%), and 7 genera, generalized by 53 (74, 64%) species and varieties. The flora-systematic analysis shows that the species composition of the Akdarya Reservoir’s algophore has a peculiar feature, where the data obtained in the Far East can be used in the study of the ecosystem of the Akdarya Reservoir, as biodiversity of primary producers. \u0000Background. The reservoir plays a major role in the formation of ecosystems of certain geographical areas. The comprehensive study of biodiversity in a reservoir makes it possible to study and monitor environmental and biological changes in environmental factors. For this purpose, a preliminary inventory of the state of the aquatic environment and its organisms is carried out. In this regard, the objective of our research is the taxonomic analysis of the Akdarya Reservoir’s algophore. \u0000Materials and Methods. In 2014-2022 from Akdarya reservoir-More than 150 alhologic samples have been collected and processed according to the generally accepted methods of alhology and hydrobiology [5, 6]. In the laboratory, preparations were prepared from algological samples, species compositions of algae were identified by determinants and frequency of occurrence in one lens field of view was determined. The experiments were carried out using a Carl Zeiss type light microscope, eyepiece +7 micrometer, and dyes. Species composition of algae, systematics and their taxonomy have been identified with the help of the determinant [4-11, 16] and the monograph [12, 17, 18]. The chemical composition of water is analyzed by the data of UzGMNII (Uzbek Hydrometeorological Research Institute). \u0000Results. Based on taxonomic analysis, 71 species and varieties of algae (63 species, 16 variations and 2 shapes) were identified in alhologic samples from the Akdarya reservoir. They belong to 4 divisions (Cyanophyta, Bacillariophyta, Xanthophyta, Chlorophyta), 8 classes, 10 orders, 14 families and 23 genera, which are given in table 1.2. \u0000Conclusion. The Akdarya reservoir in the middle of the Zarafshan River has a large amount of suspended substances and relatively high mineralization. This factor favourably influences the development, formation and intensive distribution of the algae division of Bacillariophyta (56), Cyanophyta (9), Xantophyta (4), Chlorophyta (2) in the ecosystem of the Akdarya reservoir. The","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44406080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-141-163
P. Kuzmin, T. Skoblikova, S. A. Gorovoy, O. Otto
Objective. The study of anthropogenic impact on environmental components, primarily on woody and shrub plants, which are the main medium-forming element in natural and artificial ecosystems, is relevant. The subject of this study was the ecological and biological state of plants under conditions of technogenic stress. Materials and methods. The article presents the results of a study of the life state of woody plants. For this, test plots were laid on the territory of sanitary protection zones of industrial enterprises and in the plantings of main plantings. The quantitative content of tannins and polyphenol oxidase in plant leaves during the active growing season was determined by spectrophotometry and titrimetric analysis. Results. Vitality decreases in the following order: Betula pendula Roth.> Sorbus aucuparia L.> Rosa majalis Herrn.> Acer negundo L.> Tilia cordata Mill. In plantations of technogenic territories, an increase in damage to the leaf blade is noted, a greater number of dry branches appear in the crown of a tree, compared to the control zone. Thus, in the study area, the lowest life state scores were recorded in Tilia cordata Mill., And the highest vital state scores were recorded in silver birch. In mountain ash, wild rose and American maple, the vital state is average. The increase in the activity of polyphenol oxidase was observed in plantations of technogenic territories, which is a consequence of intensive anthropogenic load on woody plants. Increased activity of polyphenol oxidase helps to decrease the content of tannins in plant leaves. Betula pendula Roth. Sorbus aucuparia L. in the SPZ of industrial enterprises in July, the accumulation of tannins is more intense than in the control plantations. Conclusion. Betula pendula Roth., Sorbus aucuparia L. in the SPZ of industrial enterprises in July, the accumulation of tannins is more intense than in the control plantations. Spectrophotometric determination of activity helps to understand the reasons why the content of tannins increases or decreases. This fact indicates the participation of tannins in the complex of adaptive reactions of plants, which are associated with protection from aerogenic pollutants. As a result of the study, the most resistant to anthropogenic stress plant species were identified: silver birch, cinnamon rose, and rowan tree.
{"title":"RESEARCH OF THE STATE OF WOODY AND BRUSHWOOD PLANTS UNDER ANTHROPOGENIC STRESS CONDITIONS","authors":"P. Kuzmin, T. Skoblikova, S. A. Gorovoy, O. Otto","doi":"10.12731/2658-6649-2023-15-1-141-163","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-141-163","url":null,"abstract":"Objective. The study of anthropogenic impact on environmental components, primarily on woody and shrub plants, which are the main medium-forming element in natural and artificial ecosystems, is relevant. The subject of this study was the ecological and biological state of plants under conditions of technogenic stress. \u0000Materials and methods. The article presents the results of a study of the life state of woody plants. For this, test plots were laid on the territory of sanitary protection zones of industrial enterprises and in the plantings of main plantings. The quantitative content of tannins and polyphenol oxidase in plant leaves during the active growing season was determined by spectrophotometry and titrimetric analysis. \u0000Results. Vitality decreases in the following order: Betula pendula Roth.> Sorbus aucuparia L.> Rosa majalis Herrn.> Acer negundo L.> Tilia cordata Mill. In plantations of technogenic territories, an increase in damage to the leaf blade is noted, a greater number of dry branches appear in the crown of a tree, compared to the control zone. Thus, in the study area, the lowest life state scores were recorded in Tilia cordata Mill., And the highest vital state scores were recorded in silver birch. In mountain ash, wild rose and American maple, the vital state is average. The increase in the activity of polyphenol oxidase was observed in plantations of technogenic territories, which is a consequence of intensive anthropogenic load on woody plants. Increased activity of polyphenol oxidase helps to decrease the content of tannins in plant leaves. Betula pendula Roth. Sorbus aucuparia L. in the SPZ of industrial enterprises in July, the accumulation of tannins is more intense than in the control plantations. \u0000Conclusion. Betula pendula Roth., Sorbus aucuparia L. in the SPZ of industrial enterprises in July, the accumulation of tannins is more intense than in the control plantations. Spectrophotometric determination of activity helps to understand the reasons why the content of tannins increases or decreases. This fact indicates the participation of tannins in the complex of adaptive reactions of plants, which are associated with protection from aerogenic pollutants. As a result of the study, the most resistant to anthropogenic stress plant species were identified: silver birch, cinnamon rose, and rowan tree.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47103408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-123-140
E. R. Nikonorova, A. A. Nikonorov, E. V. Popova, E. Agletdinov, A. Sinitskii, A. Tinkov
Background. Oxidative stress plays an important role in the pathogenesis of metabolic-associated fatty liver disease (MAFLD). Antioxidant trace elements as cofactors of antioxidant enzymes and metalloproteins are involved in this process. Zinc being an important antioxidant may have a positive effect on the treatment of liver pathology. The study aimed to assess the effect of preventive zinc supplementation on MAFLD in rats. Materials and Methods. A total of 26 three-month-old female Wistar rats were used in the present study. The activity of the antioxidant enzymes superoxide dismutase and catalase, some redox status markers, such as ceruloplasmin, oxidized tryptophan, dithyrosines, total thiols, carbonyls, TBARS, and uric acid were evaluated. Oxidative stress biomarkers were studied spectrophotometrically. Results. MAFLD was accompanied by hyperuricemia and a decrease in serum dityrosines. The addition of Zn to the diet prevented the development of steatosis, decreased the level of oxidized tryptophan in the liver, and paradoxically caused hyperuricemia in the MAFLD model used. Zn supplementation had a positive effect on the prevention of MAFLD, had a little effect on redox status of animals but caused paradoxical hyperuricemia. Future studies are needed to establish the mechanisms of the Zn effect at the cellular level.
{"title":"PREVENTIVE ZINC SUPPLEMENTATION EFFECT ON REDOX STATUS IN RAT MODEL OF MAFLD","authors":"E. R. Nikonorova, A. A. Nikonorov, E. V. Popova, E. Agletdinov, A. Sinitskii, A. Tinkov","doi":"10.12731/2658-6649-2023-15-1-123-140","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-123-140","url":null,"abstract":"Background. Oxidative stress plays an important role in the pathogenesis of metabolic-associated fatty liver disease (MAFLD). Antioxidant trace elements as cofactors of antioxidant enzymes and metalloproteins are involved in this process. Zinc being an important antioxidant may have a positive effect on the treatment of liver pathology. The study aimed to assess the effect of preventive zinc supplementation on MAFLD in rats. \u0000Materials and Methods. A total of 26 three-month-old female Wistar rats were used in the present study. The activity of the antioxidant enzymes superoxide dismutase and catalase, some redox status markers, such as ceruloplasmin, oxidized tryptophan, dithyrosines, total thiols, carbonyls, TBARS, and uric acid were evaluated. Oxidative stress biomarkers were studied spectrophotometrically. \u0000Results. MAFLD was accompanied by hyperuricemia and a decrease in serum dityrosines. The addition of Zn to the diet prevented the development of steatosis, decreased the level of oxidized tryptophan in the liver, and paradoxically caused hyperuricemia in the MAFLD model used. Zn supplementation had a positive effect on the prevention of MAFLD, had a little effect on redox status of animals but caused paradoxical hyperuricemia. Future studies are needed to establish the mechanisms of the Zn effect at the cellular level.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44221036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-294-307
T. L. Marugina, D. V. Kiprin, Anna I. Cherevatenko
Background. When planning orthopedic restoration of significantly destroyed teeth with signs of apical periodontitis, it is necessary to assess the complexity of root canal anatomy as one of the factors influencing successful endodontic dental treatment. Modern approaches in endodontics allow in most cases to achieve the restoration of bone tissue, as well as the elimination of the focus of chronic infection, which allows for subsequent orthopedic dental treatment in order to restore their function and increase the percentage of survival in the oral cavity. Purpose. Improving the efficiency of orthopedic restoration of teeth with chronic odontogenic infection. Materials and methods. 64 patients aged 18 to 45 were examined. All had clinical signs of failed endodontic treatment of the incisors in the upper and lower jaws with a dark, radiolucent focus in the apex region, as well as significant destruction of the crown requiring orthopedic restoration. The assessment of radiographic parameters was based on CBCT, and mobility was assessed clinically. The results were evaluated after 6, 12, and 24 months. Results. All patients showed different signs of restoration of the bone tissue after 6 and 12 months and complete restoration of the bone tissue 24 months after the treatment. No pathological tooth mobility was found 24 months after the end of treatment in 100% (primary endodontic treatment) and 97.5% (repeated endodontic treatment) of patients. Conclusion. The analysis of the anatomy of the root canals, and, accordingly, the complexity in biomechanical cleaning and washing of the root canals affects the decision to carry out treatment in one or two visits.
{"title":"THE ROLE OF ENDODONTICS IN THE TREATMENT OF CHRONIC ODONTOGENIC DISEASES IN PREPARATION FOR PROSTHETICS","authors":"T. L. Marugina, D. V. Kiprin, Anna I. Cherevatenko","doi":"10.12731/2658-6649-2023-15-1-294-307","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-294-307","url":null,"abstract":"Background. When planning orthopedic restoration of significantly destroyed teeth with signs of apical periodontitis, it is necessary to assess the complexity of root canal anatomy as one of the factors influencing successful endodontic dental treatment. Modern approaches in endodontics allow in most cases to achieve the restoration of bone tissue, as well as the elimination of the focus of chronic infection, which allows for subsequent orthopedic dental treatment in order to restore their function and increase the percentage of survival in the oral cavity. \u0000Purpose. Improving the efficiency of orthopedic restoration of teeth with chronic odontogenic infection. \u0000Materials and methods. 64 patients aged 18 to 45 were examined. All had clinical signs of failed endodontic treatment of the incisors in the upper and lower jaws with a dark, radiolucent focus in the apex region, as well as significant destruction of the crown requiring orthopedic restoration. The assessment of radiographic parameters was based on CBCT, and mobility was assessed clinically. The results were evaluated after 6, 12, and 24 months. \u0000Results. All patients showed different signs of restoration of the bone tissue after 6 and 12 months and complete restoration of the bone tissue 24 months after the treatment. No pathological tooth mobility was found 24 months after the end of treatment in 100% (primary endodontic treatment) and 97.5% (repeated endodontic treatment) of patients. \u0000Conclusion. The analysis of the anatomy of the root canals, and, accordingly, the complexity in biomechanical cleaning and washing of the root canals affects the decision to carry out treatment in one or two visits.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42939196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-28DOI: 10.12731/2658-6649-2023-15-1-179-207
E. Chernobai, A. Surov, N. A. Rezun, Olga N. Onishchenko, Sergey A. Oleinik
Line breeding is often used in purebred animal husbandry, although the combination of lines may affect undesirable result. Therefore, it is very important for animal breeders to know which lines of animals can be combined to produce highly productive offspring with high meat and wool properties. This article studies the influence of interline selection of Russian meat merino breed on wool productivity, quality and skin histostructure. We found that the highest clipping was in the animals of group III obtained from ME-50 line rams and AS-30 line ewes. Ewes exceeded their peers of group II from the intraline AC-30 selection and peers of group IV from AS-30 line rams and ME-50 line queens. At the same time, ewes of group III insignificantly exceeded peers of group I from intraline selection of ME-50 line animals by 2.0% (P>0.05). Animals of group III had rather high fleece indices in terms of the wool condition due to the influence of ME-50 rams. Moreover, they had the highest ratio of “fat:sweat” (0.84), which confirms the high technological wool properties of this genotype. The quality of sheepskins depends on the nature of the connection of collagen fibers in the reticular layer. In terms of the thickness of the skin reticular layer young ewes of the group III exceeded their peers in groups I, II and IV by 5.3% (P> 0.05), 21.9% ( P<0.01) and 12.0% (P<0.05) respectively.
{"title":"WOOL PRODUCTIVITY AND QUALITY OF RUSSIAN MEAT MERINO SHEEP FROM INTRA- AND INTERLINE SELECTION","authors":"E. Chernobai, A. Surov, N. A. Rezun, Olga N. Onishchenko, Sergey A. Oleinik","doi":"10.12731/2658-6649-2023-15-1-179-207","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-1-179-207","url":null,"abstract":"Line breeding is often used in purebred animal husbandry, although the combination of lines may affect undesirable result. Therefore, it is very important for animal breeders to know which lines of animals can be combined to produce highly productive offspring with high meat and wool properties. This article studies the influence of interline selection of Russian meat merino breed on wool productivity, quality and skin histostructure. We found that the highest clipping was in the animals of group III obtained from ME-50 line rams and AS-30 line ewes. Ewes exceeded their peers of group II from the intraline AC-30 selection and peers of group IV from AS-30 line rams and ME-50 line queens. At the same time, ewes of group III insignificantly exceeded peers of group I from intraline selection of ME-50 line animals by 2.0% (P>0.05). Animals of group III had rather high fleece indices in terms of the wool condition due to the influence of ME-50 rams. Moreover, they had the highest ratio of “fat:sweat” (0.84), which confirms the high technological wool properties of this genotype. The quality of sheepskins depends on the nature of the connection of collagen fibers in the reticular layer. In terms of the thickness of the skin reticular layer young ewes of the group III exceeded their peers in groups I, II and IV by 5.3% (P> 0.05), 21.9% ( P<0.01) and 12.0% (P<0.05) respectively.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48486127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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