Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.161
J Guzzetti, I Marando, M Owen, R Matthews, C Yates, S Banks
Abstract Introduction Changes in cognitive performance during shiftwork due to fatigue and circadian misalignment are well-documented. However experimental evaluations of shiftwork schedules are often limited to basic tasks such as vigilance and attention. The current study evaluated several higher order cognitive functions such as memory and task switching during four simulated shiftwork schedules. Methods N=27 completed a 10-day laboratory shiftwork simulation. They were randomly assigned to one of four shiftwork conditions: Condition A, 4h-on/4h-off/8h-on/8h-off schedule; Condition B, 6h-on/6h-off schedule; Conditions C and D represented to different sections of a 4h-on/4h-on call/4h-off/4h-on/4h-on call/4h-off schedule. The Automated Neuropsychological Assessment Metrics (ANAM) was used to assess cognitive function. The tasks included in this analysis were Code Substitution (CDS/CDD), Pursuit Tracking (PUR), Matching to Sample (M2S), and Switching Task (SWT). Stability of performance during waking was compared between the conditions using Kruskal-Wallis tests. Results The analysis of cognitive performance tasks yielded mixed findings. Performance on all tasks was ranked from best to worst: Condition D (>Conditions A, B, C; all p < .05), Condition A (>Conditions B, C; p < .05 and p <.001, respectively), Condition B, Condition C. Regarding stability of higher order cognitive function across the waking day, Condition A exhibited the worst stability, and was the only condition whereby performance degraded across the wake period. Discussion These findings highlight the variability in cognitive capacities during different shiftwork schedules. It is important to examine higher order cognitive function, and other cognitive abilities during shiftwork, when evaluating different shiftwork schedules.
{"title":"P076 Comparing Four Different Simulated Shiftwork Schedules on Higher order Cognitive Function","authors":"J Guzzetti, I Marando, M Owen, R Matthews, C Yates, S Banks","doi":"10.1093/sleepadvances/zpad035.161","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.161","url":null,"abstract":"Abstract Introduction Changes in cognitive performance during shiftwork due to fatigue and circadian misalignment are well-documented. However experimental evaluations of shiftwork schedules are often limited to basic tasks such as vigilance and attention. The current study evaluated several higher order cognitive functions such as memory and task switching during four simulated shiftwork schedules. Methods N=27 completed a 10-day laboratory shiftwork simulation. They were randomly assigned to one of four shiftwork conditions: Condition A, 4h-on/4h-off/8h-on/8h-off schedule; Condition B, 6h-on/6h-off schedule; Conditions C and D represented to different sections of a 4h-on/4h-on call/4h-off/4h-on/4h-on call/4h-off schedule. The Automated Neuropsychological Assessment Metrics (ANAM) was used to assess cognitive function. The tasks included in this analysis were Code Substitution (CDS/CDD), Pursuit Tracking (PUR), Matching to Sample (M2S), and Switching Task (SWT). Stability of performance during waking was compared between the conditions using Kruskal-Wallis tests. Results The analysis of cognitive performance tasks yielded mixed findings. Performance on all tasks was ranked from best to worst: Condition D (&gt;Conditions A, B, C; all p &lt; .05), Condition A (&gt;Conditions B, C; p &lt; .05 and p &lt;.001, respectively), Condition B, Condition C. Regarding stability of higher order cognitive function across the waking day, Condition A exhibited the worst stability, and was the only condition whereby performance degraded across the wake period. Discussion These findings highlight the variability in cognitive capacities during different shiftwork schedules. It is important to examine higher order cognitive function, and other cognitive abilities during shiftwork, when evaluating different shiftwork schedules.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"180 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136053889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.087
D Park, U Ryu, S Mun
Abstract Introduction Most pediatric patients with obstructive sleep apnea (OSA) are known to be treated with adenotonsillectomy (AT). However, in some of them, positive airway pressure (PAP) can be used for underlying diseases or in case of AT failure. Thus, PAP adherence and compliance were compared in pediatric OSA to adult OSA. Methods A retrospective study was conducted on 17 children and 167 adults who had performed polysomnography (PSG) and were prescribed PAP and followed up for more than 3 months from July 2018 to January 2023. Adherence was defined as the percentage of patients continuing to use PAP after prescription and compliance was defined as an average of more than 4 hours per night usage of 70% of the monitoring days. Results There were 11 males (64.7%) in pediatric and 141 males (84.4%) in adult patients. The mean age was 8.0 years (6.50-12.50) in pediatric and 50.0 years (41.00-58.00) in adult patients. The mean apnea hypopnea index (AHI) (37.0 vs 50.7) and Lowest O2 saturation (79.4% vs 75.5%) did not show any differences in the 2 groups. Longest apnea showed considerable differences (25.9 sec vs 50.8 sec) (p=0.000). After 18 months of PAP usage, AHI dropped from 37.0 to 5.1 vs 50.7 to 2.6, adherence decreased from 94.1% to 41.2% vs 90.4% to 38.9% (p=0.944), compliance reduced from 64.7% to 28.9% vs 67.0% vs 29.3% (p=0.268) in pediatric and adults groups. Conclusions There were no significant differences in adherence and compliance with PAP in children compared to adults.
大多数患有阻塞性睡眠呼吸暂停(OSA)的儿童患者都接受腺扁桃体切除术(AT)治疗。然而，在其中一些病例中，气道正压通气(PAP)可用于潜在疾病或AT失败的情况。因此，比较了儿童OSA与成人OSA的PAP依从性和依从性。方法回顾性研究2018年7月至2023年1月行多导睡眠描记术(PSG)并给予PAP治疗的17名儿童和167名成人，随访时间超过3个月。依从性定义为处方后继续使用PAP的患者百分比，依从性定义为在70%的监测天数中平均每晚使用超过4小时。结果小儿患者中男性11例(64.7%)，成人患者中男性141例(84.4%)。儿童患者平均年龄为8.0岁(6.50 ~ 12.50岁)，成人患者平均年龄为50.0岁(41.00 ~ 58.00岁)。两组患者的平均呼吸暂停低通气指数(AHI) (37.0 vs 50.7)和最低氧饱和度(79.4% vs 75.5%)无统计学差异。最长的呼吸暂停有显著差异(25.9秒vs 50.8秒)(p=0.000)。使用PAP 18个月后，AHI从37.0降至5.1，而50.7降至2.6，依从性从94.1%降至41.2%，从90.4%降至38.9% (p=0.944)，依从性从64.7%降至28.9%，从67.0%降至29.3% (p=0.268)。结论:与成人相比，儿童PAP的依从性和依从性无显著差异。
{"title":"P002 Positive airway pressure adherence in children with sleep apnea may be similar to adults","authors":"D Park, U Ryu, S Mun","doi":"10.1093/sleepadvances/zpad035.087","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.087","url":null,"abstract":"Abstract Introduction Most pediatric patients with obstructive sleep apnea (OSA) are known to be treated with adenotonsillectomy (AT). However, in some of them, positive airway pressure (PAP) can be used for underlying diseases or in case of AT failure. Thus, PAP adherence and compliance were compared in pediatric OSA to adult OSA. Methods A retrospective study was conducted on 17 children and 167 adults who had performed polysomnography (PSG) and were prescribed PAP and followed up for more than 3 months from July 2018 to January 2023. Adherence was defined as the percentage of patients continuing to use PAP after prescription and compliance was defined as an average of more than 4 hours per night usage of 70% of the monitoring days. Results There were 11 males (64.7%) in pediatric and 141 males (84.4%) in adult patients. The mean age was 8.0 years (6.50-12.50) in pediatric and 50.0 years (41.00-58.00) in adult patients. The mean apnea hypopnea index (AHI) (37.0 vs 50.7) and Lowest O2 saturation (79.4% vs 75.5%) did not show any differences in the 2 groups. Longest apnea showed considerable differences (25.9 sec vs 50.8 sec) (p=0.000). After 18 months of PAP usage, AHI dropped from 37.0 to 5.1 vs 50.7 to 2.6, adherence decreased from 94.1% to 41.2% vs 90.4% to 38.9% (p=0.944), compliance reduced from 64.7% to 28.9% vs 67.0% vs 29.3% (p=0.268) in pediatric and adults groups. Conclusions There were no significant differences in adherence and compliance with PAP in children compared to adults.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136054624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.063
C Tang, K Meredith-Jones, L Signal, B Galland
Abstract Introduction Good sleep quality is critical for good sleep health, but how sleep quality is defined remains uncertain; most defining it based solely on subjective or objective measures, and more recently, a combination of the two. PSG-derived sleep efficiency and WASO are linked to subjective sleep quality in healthy adults, but whether this is the same in adolescents (an age group notorious for not getting enough sleep), remains unknown. Aims To investigate which objective measures of sleep correlate with next-day ratings of sleep quality (primary outcome), sleep sufficiency, morning and daytime sleepiness, mood and concentration. Methods Seventy-one 16-17 y-olds (50% female) without anxiety/depression symptoms, completed a week of actigraphy and daily ratings of the subjective elements described above (469 days analysed). Statistical analyses used generalised estimating equation models. Results In unadjusted models, sleep quality showed significant within- and between-subject relationships with variables of sleep timing, amount, efficiency and variability. However after adjustment, total sleep time (TST) was the only metric that remained significant; for every 1 h less TST/night, teens were 1.56 (95%CI: 1.29, 1.88) times more likely to rate their sleep quality as poor rather than good. TST also correlated with daily mood ratings, and awakenings with morning sleepiness. No other significant relationships were found. Discussion The key sleep metric contributing to perceptions of sleep quality in adolescents was in fact one related to sleep quantity. Surprisingly, none of the sleep quality metrics used in sleep quality guidelines, linked to subjective ratings of sleep quality in this age group.
{"title":"O063 Objective Sleep Quality Metrics underlying next-day Sleep Quality Ratings in Adolescents","authors":"C Tang, K Meredith-Jones, L Signal, B Galland","doi":"10.1093/sleepadvances/zpad035.063","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.063","url":null,"abstract":"Abstract Introduction Good sleep quality is critical for good sleep health, but how sleep quality is defined remains uncertain; most defining it based solely on subjective or objective measures, and more recently, a combination of the two. PSG-derived sleep efficiency and WASO are linked to subjective sleep quality in healthy adults, but whether this is the same in adolescents (an age group notorious for not getting enough sleep), remains unknown. Aims To investigate which objective measures of sleep correlate with next-day ratings of sleep quality (primary outcome), sleep sufficiency, morning and daytime sleepiness, mood and concentration. Methods Seventy-one 16-17 y-olds (50% female) without anxiety/depression symptoms, completed a week of actigraphy and daily ratings of the subjective elements described above (469 days analysed). Statistical analyses used generalised estimating equation models. Results In unadjusted models, sleep quality showed significant within- and between-subject relationships with variables of sleep timing, amount, efficiency and variability. However after adjustment, total sleep time (TST) was the only metric that remained significant; for every 1 h less TST/night, teens were 1.56 (95%CI: 1.29, 1.88) times more likely to rate their sleep quality as poor rather than good. TST also correlated with daily mood ratings, and awakenings with morning sleepiness. No other significant relationships were found. Discussion The key sleep metric contributing to perceptions of sleep quality in adolescents was in fact one related to sleep quantity. Surprisingly, none of the sleep quality metrics used in sleep quality guidelines, linked to subjective ratings of sleep quality in this age group.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136054625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.059
C Pattinson, D Mann, J McKenzie, K Rossa, S Edmed, E Westwood, S Smith
Abstract Introduction Light plays an important role in the timing of children’s circadian system. Artificial manipulation of the timing, intensity, spectra, and duration of light exposure has increased, but with little consideration of the impact on children’s development, health, and wellbeing. Children are exposed to brighter nights, darker days, and less natural light environments than prior generations. Exploring the 24-hour light environment is a critical first step in understanding how light affects children. Methods We conducted a pilot feasibility and acceptability study. The study is of children aged 5 – 8 years. Children wore a miniature spectrometer and an actigraph for 48-hours. During this period, their parents completed a survey and daily time-use diary. At the end of the study, children undergo a short evaluation interview, as this is a new form of wearable not previously used with children. This study examines the feasibility and potential utility of this form of measurement. Results 5 children have been recruited into the study (3 boys, 2 girls). Initial feasibility testing with children supports high acceptability and adherence to the study protocol. This presentation will focus on both the technology development aspects, useability and feasibility in children, and preliminary results. Discussion This study presents preliminary data that supports the feasibility of novel light exposure metrics. Understanding the impact of increased use of digital devices by children, and increased control and manipulation of their light environments, requires new measures and protocols. These tools will help improve understanding of the effects of light on children’s sleep.
{"title":"O059 Exploring Environmental Light Exposure in Children: A novel pilot spectrometer study","authors":"C Pattinson, D Mann, J McKenzie, K Rossa, S Edmed, E Westwood, S Smith","doi":"10.1093/sleepadvances/zpad035.059","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.059","url":null,"abstract":"Abstract Introduction Light plays an important role in the timing of children’s circadian system. Artificial manipulation of the timing, intensity, spectra, and duration of light exposure has increased, but with little consideration of the impact on children’s development, health, and wellbeing. Children are exposed to brighter nights, darker days, and less natural light environments than prior generations. Exploring the 24-hour light environment is a critical first step in understanding how light affects children. Methods We conducted a pilot feasibility and acceptability study. The study is of children aged 5 – 8 years. Children wore a miniature spectrometer and an actigraph for 48-hours. During this period, their parents completed a survey and daily time-use diary. At the end of the study, children undergo a short evaluation interview, as this is a new form of wearable not previously used with children. This study examines the feasibility and potential utility of this form of measurement. Results 5 children have been recruited into the study (3 boys, 2 girls). Initial feasibility testing with children supports high acceptability and adherence to the study protocol. This presentation will focus on both the technology development aspects, useability and feasibility in children, and preliminary results. Discussion This study presents preliminary data that supports the feasibility of novel light exposure metrics. Understanding the impact of increased use of digital devices by children, and increased control and manipulation of their light environments, requires new measures and protocols. These tools will help improve understanding of the effects of light on children’s sleep.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136054881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.132
J Chapman, T Kao, J Teh, C Haroutonian, R Grunstein, S Naismith, A D'Rozario
Abstract Introduction Slow wave activity during non-rapid eye movement (NREM) sleep has been linked with memory consolidation in healthy older adults. To date, there has been limited research in mild cognitively impaired populations, particularly looking across the whole brain using high density EEG. We aimed to determine if the dynamics of slow wave activity (delta power) during the first NREM sleep cycle differ between patients with mild cognitive impairment (MCI) and healthy older adults. Methods Participants were assessed for MCI by a panel of neuropsychologists and clinicians. They underwent full polysomnography including high-density EEG (256 electrodes). We computed the delta power (0.5-4.5Hz) for each NREM cycle and slope between sleep onset and the peak of delta in the first NREM sleep cycle (rise-rate) which were compared between groups using t-tests. Results 17 older adults with MCI and 21 older healthy controls were assessed. The mean delta power in the first NREM cycle did not differ between MCI and controls across the whole brain, but the global rise-rate (1/min) of MCI and controls was 0.0015 and 0.0032 respectively (t-value -2.35, p=0.025). Discussion Global slow wave dynamics in the first NREM period appear to be altered in patients with MCI compared with age-matched controls. The gentler slope of rise-rate to the first delta peak in MCI patients than in healthy controls may indicate the dysfunction of sleep homeostasis in MCI patients. Regional slow wave dynamics, ultra-low frequency delta (0.25-1Hz), and associations with sleep dependent memory consolidation will further be explored.
{"title":"P047 Slow Wave Dynamics in Mild Cognitive Impairment compared with Age Matched Controls: A High Density EEG study.","authors":"J Chapman, T Kao, J Teh, C Haroutonian, R Grunstein, S Naismith, A D'Rozario","doi":"10.1093/sleepadvances/zpad035.132","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.132","url":null,"abstract":"Abstract Introduction Slow wave activity during non-rapid eye movement (NREM) sleep has been linked with memory consolidation in healthy older adults. To date, there has been limited research in mild cognitively impaired populations, particularly looking across the whole brain using high density EEG. We aimed to determine if the dynamics of slow wave activity (delta power) during the first NREM sleep cycle differ between patients with mild cognitive impairment (MCI) and healthy older adults. Methods Participants were assessed for MCI by a panel of neuropsychologists and clinicians. They underwent full polysomnography including high-density EEG (256 electrodes). We computed the delta power (0.5-4.5Hz) for each NREM cycle and slope between sleep onset and the peak of delta in the first NREM sleep cycle (rise-rate) which were compared between groups using t-tests. Results 17 older adults with MCI and 21 older healthy controls were assessed. The mean delta power in the first NREM cycle did not differ between MCI and controls across the whole brain, but the global rise-rate (1/min) of MCI and controls was 0.0015 and 0.0032 respectively (t-value -2.35, p=0.025). Discussion Global slow wave dynamics in the first NREM period appear to be altered in patients with MCI compared with age-matched controls. The gentler slope of rise-rate to the first delta peak in MCI patients than in healthy controls may indicate the dysfunction of sleep homeostasis in MCI patients. Regional slow wave dynamics, ultra-low frequency delta (0.25-1Hz), and associations with sleep dependent memory consolidation will further be explored.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136055009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.073
D Easton, C Gupta, G Vincent, S Ferguson
Abstract Introduction Physical activity might be a nonphotic strategy which could improve cognitive performance for nightshift workers. Innate characteristics like circadian type may also influence individual performance. Thus, this study explores the relationship between circadian type and physical activity on cognition over consecutive nightshifts. Methods Thirty-two healthy adults (age M±SD: 24.3±4.6 years; 19 females) participated in a 7-day laboratory study, with 5 nightshifts (2200-0600). Participants were randomised into the Breaking up sitting (BUS; n=19) or Sedentary (SED; n=13) condition. Overnight, BUS participants completed 3-min bouts of light-intensity walking every 30-min, while SED participants remained seated. At 2200, 0000, 0200, 0400 and 0600, participants completed the 10-min Psychomotor Vigilance Task (mean RRT). Participants completed the 11-item revised Circadian Type Inventory (factor 1: rigid/flexible; factor 2: languid/vigorous), resulting in four-subgroups (rigid; n= 12, flexible; n= 11, and languid; n= 11, vigorous; n= 13). Participants may only be one type from either factor (i.e. rigid and vigorous). Results Linear mixed models showed a significant 3-way interaction between nightshift (1-5), condition (BUS, SED), and circadian type (rigid/flexible) for mean RRT (p=0.03), such that flexible types in the Breaking up sitting condition outperformed Sedentary flexible types and Breaking up sitting rigid types, with performance worse on the first nightshift. There were no significant interactions between nightshift, condition and circadian type (languid/vigorous). Discussion Breaking up sitting improved performance for flexible types over rigid types. These findings have significant implications for nightshift rostering, suggesting that incorporating breaking up sitting may optimise cognitive performance, and therefore work efficiency.
{"title":"O073 The Relationship between Circadian type and Physical Activity on Cognitive Performance during Simulated Nightshifts: A Randomised Controlled Trial.","authors":"D Easton, C Gupta, G Vincent, S Ferguson","doi":"10.1093/sleepadvances/zpad035.073","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.073","url":null,"abstract":"Abstract Introduction Physical activity might be a nonphotic strategy which could improve cognitive performance for nightshift workers. Innate characteristics like circadian type may also influence individual performance. Thus, this study explores the relationship between circadian type and physical activity on cognition over consecutive nightshifts. Methods Thirty-two healthy adults (age M±SD: 24.3±4.6 years; 19 females) participated in a 7-day laboratory study, with 5 nightshifts (2200-0600). Participants were randomised into the Breaking up sitting (BUS; n=19) or Sedentary (SED; n=13) condition. Overnight, BUS participants completed 3-min bouts of light-intensity walking every 30-min, while SED participants remained seated. At 2200, 0000, 0200, 0400 and 0600, participants completed the 10-min Psychomotor Vigilance Task (mean RRT). Participants completed the 11-item revised Circadian Type Inventory (factor 1: rigid/flexible; factor 2: languid/vigorous), resulting in four-subgroups (rigid; n= 12, flexible; n= 11, and languid; n= 11, vigorous; n= 13). Participants may only be one type from either factor (i.e. rigid and vigorous). Results Linear mixed models showed a significant 3-way interaction between nightshift (1-5), condition (BUS, SED), and circadian type (rigid/flexible) for mean RRT (p=0.03), such that flexible types in the Breaking up sitting condition outperformed Sedentary flexible types and Breaking up sitting rigid types, with performance worse on the first nightshift. There were no significant interactions between nightshift, condition and circadian type (languid/vigorous). Discussion Breaking up sitting improved performance for flexible types over rigid types. These findings have significant implications for nightshift rostering, suggesting that incorporating breaking up sitting may optimise cognitive performance, and therefore work efficiency.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136054373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.045
S Gadam, K Rossa, C Pattinson, S Shekari Soleimanloo, D Mann, P Salmon, K Sullivan, S Smith
Abstract Introduction Young adulthood is a critical developmental period typified by heightened exposure to stress, and a tendency towards insufficient sleep. The relationship between sleep loss and stress may have lifelong health consequences. Currently, our understanding of this relationship in young adults is limited. Heart rate variability (HRV) is an important indicator of balance in the autonomic nervous system. We examined the association between sleep duration and HRV in response to cognitive stressors. Methods Seventy-six young adults (M=20.6±1.9, 72.4% female) who self-identified as short sleepers were recruited. Habitual sleep duration was monitored with actigraphy for two weeks. Participants subsequently underwent an in-lab experiment where their HRV was recorded during baseline, and during a cognitive stress condition involving the completion of computerised cognitive stress tasks. Participants also reported their habitual stress levels and sleep quality. Results Actigraphy assessment revealed that participants slept within the recommended sleep durations (M=7.8±0.7). The participants reported high habitual stress but normal sleep quality. Our moderation analysis indicates that shorter sleep duration was associated with elevated HRV during the cognitively demanding tasks. Conclusions Our findings demonstrate an association between sleep duration and HRV in the context of a cognitive stressor, indicating that sleep and stress are related in young adults. An unexpected negative relationship between sleep duration and HRV during the cognitively demanding tasks suggests complexity in this relationship; however, we should still look to reduce stress and improve sleep where we can in young adults. This association may be better understood via direct manipulation of sleep duration.
{"title":"O045 Sleep Duration is Associated with Young Adult's Heart Rate Variability Response to Stress","authors":"S Gadam, K Rossa, C Pattinson, S Shekari Soleimanloo, D Mann, P Salmon, K Sullivan, S Smith","doi":"10.1093/sleepadvances/zpad035.045","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.045","url":null,"abstract":"Abstract Introduction Young adulthood is a critical developmental period typified by heightened exposure to stress, and a tendency towards insufficient sleep. The relationship between sleep loss and stress may have lifelong health consequences. Currently, our understanding of this relationship in young adults is limited. Heart rate variability (HRV) is an important indicator of balance in the autonomic nervous system. We examined the association between sleep duration and HRV in response to cognitive stressors. Methods Seventy-six young adults (M=20.6±1.9, 72.4% female) who self-identified as short sleepers were recruited. Habitual sleep duration was monitored with actigraphy for two weeks. Participants subsequently underwent an in-lab experiment where their HRV was recorded during baseline, and during a cognitive stress condition involving the completion of computerised cognitive stress tasks. Participants also reported their habitual stress levels and sleep quality. Results Actigraphy assessment revealed that participants slept within the recommended sleep durations (M=7.8±0.7). The participants reported high habitual stress but normal sleep quality. Our moderation analysis indicates that shorter sleep duration was associated with elevated HRV during the cognitively demanding tasks. Conclusions Our findings demonstrate an association between sleep duration and HRV in the context of a cognitive stressor, indicating that sleep and stress are related in young adults. An unexpected negative relationship between sleep duration and HRV during the cognitively demanding tasks suggests complexity in this relationship; however, we should still look to reduce stress and improve sleep where we can in young adults. This association may be better understood via direct manipulation of sleep duration.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136054617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.189
T Smithies, A Toth, M Campbell
Abstract Preliminary findings from this study were presented as a poster (P376) at Sleep Europe 2022 (https://doi.org/10.1111/jsr.13740). Introduction Sleep loss is presumed by academics and esport (organised competitive video-game play) athletes to be an in-game esport performance hindrance, primarily due to its well understood effects on multiple domains of cognitive performance. However, the effects of acute sleep loss specifically on esports performance have not been explored. We aimed to elucidate whether total sleep deprivation degrades in-game performance in the popular esport ‘Rocket League’. Methods Forty habitual Rocket League players were paired according to in-game ability level (twenty pairs), with one assigned to a control group (CON) and the other assigned to an intervention group (TSD). Two test sessions took place, in which paired players completed subjective and cognitive performance measures, and played seven Rocket League matches against one another. In one session, both players in a pair were well rested, while in the other, CON was rested while TSD was sleep deprived. Results Acute total sleep deprivation resulted in higher self-reported sleepiness, lower alertness and motivation, poorer performance on the Psychomotor Vigilance Task (PVT) and two-choice component of the Category Switch Task (CST). Despite this, overall in-game esport performance did not worsen due to sleep deprivation, although exploratory analysis suggests potential in-game strategy change. Discussion Our findings do not suggest that sleep loss is inconsequential for esport athletes, but rather suggest that acute bouts of sleep loss of similar/lesser severity may not be a primary concern for in-game esports performance.
{"title":"P104 The Impact of Total Sleep Deprivation on Performance in the Esport ‘Rocket League’.","authors":"T Smithies, A Toth, M Campbell","doi":"10.1093/sleepadvances/zpad035.189","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.189","url":null,"abstract":"Abstract Preliminary findings from this study were presented as a poster (P376) at Sleep Europe 2022 (https://doi.org/10.1111/jsr.13740). Introduction Sleep loss is presumed by academics and esport (organised competitive video-game play) athletes to be an in-game esport performance hindrance, primarily due to its well understood effects on multiple domains of cognitive performance. However, the effects of acute sleep loss specifically on esports performance have not been explored. We aimed to elucidate whether total sleep deprivation degrades in-game performance in the popular esport ‘Rocket League’. Methods Forty habitual Rocket League players were paired according to in-game ability level (twenty pairs), with one assigned to a control group (CON) and the other assigned to an intervention group (TSD). Two test sessions took place, in which paired players completed subjective and cognitive performance measures, and played seven Rocket League matches against one another. In one session, both players in a pair were well rested, while in the other, CON was rested while TSD was sleep deprived. Results Acute total sleep deprivation resulted in higher self-reported sleepiness, lower alertness and motivation, poorer performance on the Psychomotor Vigilance Task (PVT) and two-choice component of the Category Switch Task (CST). Despite this, overall in-game esport performance did not worsen due to sleep deprivation, although exploratory analysis suggests potential in-game strategy change. Discussion Our findings do not suggest that sleep loss is inconsequential for esport athletes, but rather suggest that acute bouts of sleep loss of similar/lesser severity may not be a primary concern for in-game esports performance.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136054770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.118
E Thomas, A Osman, L Calonzo, L Hall, M Agzarian, M Slee
Abstract Introduction Upper airway reflex responses to negative pressure are important to prevent upper airway narrowing and closure. Recent evidence indicates ~30% of people with multiple sclerosis (MS) have an impaired upper airway dilator reflex response. Thus, the aims of this study were to compare genioglossus muscle reflex responses and upper airway collapsibility in non-obese people with MS, with and without OSA. Methods Non-obese adults with MS and OSA vs MS without OSA were instrumented with pressure sensors at the choanae and epiglottis. Bipolar fine wires were inserted into the genioglossus. A nasal mask and pneumotachograph were attached to a breathing circuit to deliver brief (~250ms) suction pressure (~-12cmH2O) during early inspiration every 2-10 breaths while awake. Genioglossus reflex onset latency, peak latency and peak amplitude were quantified. The upper airway collapsibility index was the percent difference between choanal and epiglottic airway pressures during negative pressure. Results 15 people with MS (6 males), aged 48±13years, BMI=25±3kg/m-2 and AHI=13±17events/h (mean±SD) were studied. 47% had OSA (AHI>10events/h). Genioglossus reflex excitation onset latency (22±2 vs. 24±19ms), peak excitation latency (37±11 vs. 38±23ms) and peak amplitude (258±125 vs. 205±95%) were not different between OSA vs. non-OSA. The upper airway was more collapsible in people with OSA (49±32 vs. 17±16%, p=0.04). Conclusions There is a high prevalence of OSA among non-obese people with MS. There was no systematic difference in upper airway dilator muscle function. However, the upper airway is ~65% more collapsible in people with MS and OSA despite absence of obesity.
上呼吸道对负压的反射反应是防止上呼吸道狭窄和关闭的重要因素。最近的证据表明，约30%的多发性硬化症(MS)患者有上呼吸道扩张器反射反应受损。因此，本研究的目的是比较非肥胖多发性硬化症患者(伴和不伴OSA)的颏舌肌反射反应和上呼吸道塌陷性。方法对非肥胖成人多发性硬化症、阻塞性睡眠呼吸暂停与非阻塞性睡眠呼吸暂停的多发性硬化症患者在耳道和会厌处安装压力传感器。双极细导线插入颏舌肌。在清醒状态下，每2-10次呼吸，将鼻罩和气描仪连接到呼吸回路上，在早期吸气时提供短暂(~250ms)的吸入压力(~-12cmH2O)。对舌颏反射的起病潜伏期、峰潜伏期和峰幅进行量化。上呼吸道湿陷性指数为负压时后气道与会厌气道压力差的百分比。结果15例MS患者(男6例)，年龄48±13岁，BMI=25±3kg/m-2, AHI=13±17events/h (mean±SD)。47%发生OSA (ahi10事件/小时)。舌颏反射兴奋发作潜伏期(22±2 vs. 24±19ms)、兴奋峰潜伏期(37±11 vs. 38±23ms)和峰幅(258±125 vs. 205±95%)在OSA与非OSA之间无显著差异。阻塞性睡眠呼吸暂停患者的上气道更易折叠(49±32比17±16%，p=0.04)。结论非肥胖多发性硬化症患者存在较高的阻塞性睡眠呼吸暂停患病率，两组患者上气道扩张肌功能无系统性差异。然而，尽管没有肥胖，MS和OSA患者的上呼吸道可折叠性要高出约65%。
{"title":"P033 Assessment of Upper Airway Dilator Muscle Function and Collapsibility in People with Multiple Sclerosis with Versus without Sleep Apnea","authors":"E Thomas, A Osman, L Calonzo, L Hall, M Agzarian, M Slee","doi":"10.1093/sleepadvances/zpad035.118","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.118","url":null,"abstract":"Abstract Introduction Upper airway reflex responses to negative pressure are important to prevent upper airway narrowing and closure. Recent evidence indicates ~30% of people with multiple sclerosis (MS) have an impaired upper airway dilator reflex response. Thus, the aims of this study were to compare genioglossus muscle reflex responses and upper airway collapsibility in non-obese people with MS, with and without OSA. Methods Non-obese adults with MS and OSA vs MS without OSA were instrumented with pressure sensors at the choanae and epiglottis. Bipolar fine wires were inserted into the genioglossus. A nasal mask and pneumotachograph were attached to a breathing circuit to deliver brief (~250ms) suction pressure (~-12cmH2O) during early inspiration every 2-10 breaths while awake. Genioglossus reflex onset latency, peak latency and peak amplitude were quantified. The upper airway collapsibility index was the percent difference between choanal and epiglottic airway pressures during negative pressure. Results 15 people with MS (6 males), aged 48±13years, BMI=25±3kg/m-2 and AHI=13±17events/h (mean±SD) were studied. 47% had OSA (AHI&gt;10events/h). Genioglossus reflex excitation onset latency (22±2 vs. 24±19ms), peak excitation latency (37±11 vs. 38±23ms) and peak amplitude (258±125 vs. 205±95%) were not different between OSA vs. non-OSA. The upper airway was more collapsible in people with OSA (49±32 vs. 17±16%, p=0.04). Conclusions There is a high prevalence of OSA among non-obese people with MS. There was no systematic difference in upper airway dilator muscle function. However, the upper airway is ~65% more collapsible in people with MS and OSA despite absence of obesity.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136054866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1093/sleepadvances/zpad035.074
K Sansom, P Eastwood, B Brown, M Crowther, S Wanstall, N McArdle, R Adams, A Reynolds
Abstract Young adults are vulnerable to the consequences of disturbed sleep from insufficient sleep, shift work and sleep disorders. The impact of these causes of disturbed sleep on perceived work performance and quality of life (QOL) in young adults is unclear. This study sought to investigate these associations in a community sample of 22-year-old adults. Participants studied (n=565, 53% female) were a subset of the Raine Study. All were employed and provided information on sleep disorders (obstructive sleep apnoea by polysomnography and insomnia and restless legs syndrome symptoms by validated questionnaires), shift work status, habitual sleep duration, QOL (Short Form (SF) 12) and perceived work performance (categorical response: perform better, same or worse than most workers). Multinomial and linear regression models adjusted for sex, comorbidities and work hours were used to examine the associations between disturbed sleep with work performance and QOL, respectively. In total 25% of participants had a sleep disorder, 29% were shift workers, and 31% had insufficient sleep (<6 hours). Presence of a sleep disorder was associated with poorer perceived work performance (OR, 2.27; 95%CI, 1.3 – 4.1). Sleep disorders were also associated with significantly lower SF-12 mental (β, -4.19; 95%CI, -5.92 to -2.45, p<0.001) and physical (β, -1.56; 95%CI, -2.70 to -0.42, p<0.008) component scores. Shift work and insufficient sleep were not associated with either perceived work performance or QOL. Identifying and treating sleep disorders in young adults may be important given its negative association with perceived work performance and QOL.
{"title":"O074 Does Sleep Duration, Shift work or Sleep Disorder Status Predict Perceived work Performance and Quality of Life in Young Adults?","authors":"K Sansom, P Eastwood, B Brown, M Crowther, S Wanstall, N McArdle, R Adams, A Reynolds","doi":"10.1093/sleepadvances/zpad035.074","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpad035.074","url":null,"abstract":"Abstract Young adults are vulnerable to the consequences of disturbed sleep from insufficient sleep, shift work and sleep disorders. The impact of these causes of disturbed sleep on perceived work performance and quality of life (QOL) in young adults is unclear. This study sought to investigate these associations in a community sample of 22-year-old adults. Participants studied (n=565, 53% female) were a subset of the Raine Study. All were employed and provided information on sleep disorders (obstructive sleep apnoea by polysomnography and insomnia and restless legs syndrome symptoms by validated questionnaires), shift work status, habitual sleep duration, QOL (Short Form (SF) 12) and perceived work performance (categorical response: perform better, same or worse than most workers). Multinomial and linear regression models adjusted for sex, comorbidities and work hours were used to examine the associations between disturbed sleep with work performance and QOL, respectively. In total 25% of participants had a sleep disorder, 29% were shift workers, and 31% had insufficient sleep (&lt;6 hours). Presence of a sleep disorder was associated with poorer perceived work performance (OR, 2.27; 95%CI, 1.3 – 4.1). Sleep disorders were also associated with significantly lower SF-12 mental (β, -4.19; 95%CI, -5.92 to -2.45, p&lt;0.001) and physical (β, -1.56; 95%CI, -2.70 to -0.42, p&lt;0.008) component scores. Shift work and insufficient sleep were not associated with either perceived work performance or QOL. Identifying and treating sleep disorders in young adults may be important given its negative association with perceived work performance and QOL.","PeriodicalId":21861,"journal":{"name":"SLEEP Advances","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136055000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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