Pub Date : 2021-01-01DOI: 10.36303/sagp.2021.2.5.0098
IP Olwoch, M. Kotu
{"title":"The management of rhinosinusitis in general practice","authors":"IP Olwoch, M. Kotu","doi":"10.36303/sagp.2021.2.5.0098","DOIUrl":"https://doi.org/10.36303/sagp.2021.2.5.0098","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86271154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-07DOI: 10.36303/sagp.2020.2.0015
S. Steyn, De Wet Wolmarans, L. Brand
Pre-exposure prophylaxis (PrEP) refers to the use of antiretroviral drugs to prevent one from acquiring human immunodeficiency virus (HIV) infection when engaging in high-risk sexual behaviour. Adequate PrEP initiation is key in the clinical outcome and survival of not only vulnerable and high-risk populations, but also to ensure that a society which is free of HIV, is built.
{"title":"PrEPping for a healthier future – a concise update of current pharmacological HIV-prophylaxis practices","authors":"S. Steyn, De Wet Wolmarans, L. Brand","doi":"10.36303/sagp.2020.2.0015","DOIUrl":"https://doi.org/10.36303/sagp.2020.2.0015","url":null,"abstract":"Pre-exposure prophylaxis (PrEP) refers to the use of antiretroviral drugs to prevent one from acquiring human immunodeficiency virus (HIV) infection when engaging in high-risk sexual behaviour. Adequate PrEP initiation is key in the clinical outcome and survival of not only vulnerable and high-risk populations, but also to ensure that a society which is free of HIV, is built.","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90429949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-17DOI: 10.36303/sagp.2020.1.1.0001
A. Marais, E. Osuch
Insomnia is an important public health burden and is the most ubiquitous sleep disorder in the general population, requiring accurate diagnosis and effective treatment. Sleep hygiene and cognitive behavioural therapy form the foundation of management. In addition, various pharmacological entities are at hand to augment insomnia disorder. Acute insomnia requires short-term management with appropriately indicated hypnotic agents, while chronic sleeping difficulties benefit more from antidepressants. This article informs the reader about the currently available sleeping agents in South Africa, and may not include more effective or potent agents used in other parts of the world that are not yet accessible for local prescription.
{"title":"Insomnia: what is currently available","authors":"A. Marais, E. Osuch","doi":"10.36303/sagp.2020.1.1.0001","DOIUrl":"https://doi.org/10.36303/sagp.2020.1.1.0001","url":null,"abstract":"Insomnia is an important public health burden and is the most ubiquitous sleep disorder in the general population, requiring accurate diagnosis and effective treatment. Sleep hygiene and cognitive behavioural therapy form the foundation of management. In addition, various pharmacological entities are at hand to augment insomnia disorder. Acute insomnia requires short-term management with appropriately indicated hypnotic agents, while chronic sleeping difficulties benefit more from antidepressants. This article informs the reader about the currently available sleeping agents in South Africa, and may not include more effective or potent agents used in other parts of the world that are not yet accessible for local prescription.","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"217 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76626517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-28DOI: 10.36303/sagp.2021.2.5.0094
S. Schmidt
{"title":"Olopatadine in the management of allergic conjunctivitis","authors":"S. Schmidt","doi":"10.36303/sagp.2021.2.5.0094","DOIUrl":"https://doi.org/10.36303/sagp.2021.2.5.0094","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77093552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.36303/sagp.2020.1.0004
R. V. Z. Van Zyl
{"title":"Helminths in South Africa : management of cestode and trematode infections in humans","authors":"R. V. Z. Van Zyl","doi":"10.36303/sagp.2020.1.0004","DOIUrl":"https://doi.org/10.36303/sagp.2020.1.0004","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80931269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.36303/10.36303/sagp.2020.2.0016
Obw Greeff
Serotonin is said to determine our emotions, moods and affect. The physiology of serotonin implies it in the regulation of biological functions in line with our mood, like accelerated heart rate and sweating triggered by feeling flustered. Serotonin has multiple pharmacological actions in the body and alterations in serotonergic function may account for behavioural disturbances commonly observed in the elderly. The clinical effectiveness of selective 5-HT reuptake inhibitors (SSRIs) is believed to be mediated through enhancement of extracellular 5 HT. Various studies have shown that the SSRIs are better tolerated in older people compared with the tricyclic antidepressant or serotonin-norepinephrine reuptake inhibitors (SNRIs). It is obvious that serotonin plays a significant role in the emotional wellbeing of people – whether they are young or old and there are various ways of increasing serotonin in the body in order to create a feeling of wellbeing and content.
{"title":"Serotonin in the elderly","authors":"Obw Greeff","doi":"10.36303/10.36303/sagp.2020.2.0016","DOIUrl":"https://doi.org/10.36303/10.36303/sagp.2020.2.0016","url":null,"abstract":"Serotonin is said to determine our emotions, moods and affect. The physiology of serotonin implies it in the regulation of biological functions in line with our mood, like accelerated heart rate and sweating triggered by feeling flustered. Serotonin has multiple pharmacological actions in the body and alterations in serotonergic function may account for behavioural disturbances commonly observed in the elderly. The clinical effectiveness of selective 5-HT reuptake inhibitors (SSRIs) is believed to be mediated through enhancement of extracellular 5 HT. Various studies have shown that the SSRIs are better tolerated in older people compared with the tricyclic antidepressant or serotonin-norepinephrine reuptake inhibitors (SNRIs). It is obvious that serotonin plays a significant role in the emotional wellbeing of people – whether they are young or old and there are various ways of increasing serotonin in the body in order to create a feeling of wellbeing and content.","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"129 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81339592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.36303/sagp.2020.1.0006
{"title":"Potential cardiovascular benefits of GLP-1 analogues : evidence and implications for type 2 diabetes management","authors":"","doi":"10.36303/sagp.2020.1.0006","DOIUrl":"https://doi.org/10.36303/sagp.2020.1.0006","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"2004 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89513048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.36303/sagp.2020.1.0008
D. Wolmarans, L. Brand, S. Steyn
{"title":"Combination oral contraceptives - a practice-guided overview of everyday problems and their solutions","authors":"D. Wolmarans, L. Brand, S. Steyn","doi":"10.36303/sagp.2020.1.0008","DOIUrl":"https://doi.org/10.36303/sagp.2020.1.0008","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79879544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.36303/sagp.2020.1.5.0047
B. Rayner, M. Heradien
The great debate between eminent experts Prof. Brian Rayner, Nephrologist (UCT), and Dr Marshall Heradien, Cardiologist (Stellenbosch University), on “Does it matter how you lower blood pressure (BP),” was moderated by Prof. Nqoba Tsabedze, Cardiologist (Wits), and hosted online by Servier. Prof. Rayner took the position that it does not matter how you lower your blood pressure, while Dr Heradien took the position that it does. This transcript highlights their salient points and provides compelling evidence to support their respective stances.
{"title":"The great debate : does it matter how you lower blood pressure?","authors":"B. Rayner, M. Heradien","doi":"10.36303/sagp.2020.1.5.0047","DOIUrl":"https://doi.org/10.36303/sagp.2020.1.5.0047","url":null,"abstract":"The great debate between eminent experts Prof. Brian Rayner, Nephrologist (UCT), and Dr Marshall Heradien, Cardiologist (Stellenbosch University), on “Does it matter how you lower blood pressure (BP),” was moderated by Prof. Nqoba Tsabedze, Cardiologist (Wits), and hosted online by Servier. Prof. Rayner took the position that it does not matter how you lower your blood pressure, while Dr Heradien took the position that it does. This transcript highlights their salient points and provides compelling evidence to support their respective stances.","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"10 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83624952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.36303/sagp.2020.1.5.0046
D. Webb, L. Jagwanth
and improvement in quality of life. Conclusions: Consumers don’t always select an appropriate medication for abdominal pain and cramping, and require advice from a pharmacy HCP. Fostering trust and confidence is essential to ensure that the patient follows the advice given. Most South African pharmacy HCPs within these two major retail chain pharmacies recommend Buscopan as first line for treatment of abdominal cramps.
{"title":"Survey to assess management of abdominal pain and cramping in South African pharmacy chains","authors":"D. Webb, L. Jagwanth","doi":"10.36303/sagp.2020.1.5.0046","DOIUrl":"https://doi.org/10.36303/sagp.2020.1.5.0046","url":null,"abstract":"and improvement in quality of life. Conclusions: Consumers don’t always select an appropriate medication for abdominal pain and cramping, and require advice from a pharmacy HCP. Fostering trust and confidence is essential to ensure that the patient follows the advice given. Most South African pharmacy HCPs within these two major retail chain pharmacies recommend Buscopan as first line for treatment of abdominal cramps.","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79343912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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