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Insomnia in Germany—massively inadequate care? 德国的失眠症--护理严重不足?
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2024-01-04 DOI: 10.1007/s11818-023-00440-5
Anna Heidbreder, Dieter Kunz, Pitt Young, Heike Benes, François-Xavier Chalet, Cedric Vaillant, Peter Kaskel, Ingo Fietze, C. Schöbel
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引用次数: 0
Prävalenz und Prädiktoren der positiven Atemwegsdrucktherapie bei obstruktiver Schlafapnoe: eine bevölkerungsrepräsentative Studie 阻塞性睡眠呼吸暂停患者接受气道正压疗法的患病率和预测因素:一项具有人口代表性的研究
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-12-19 DOI: 10.1007/s11818-023-00435-2
Holger Woehrle, M. Arzt, J. Ficker, Melike Deger, Kimberly L. Sterling, Daniela Ehrsam-Tosi, T. Vogelmann, Sina Weinand, Ingo Fietze, Peter M. Young, C. Schoebel
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引用次数: 0
Impact of the timing of drug-induced sleep endoscopy on the apnea–hypopnea index during polysomnography 药物诱导睡眠内窥镜检查的时间对多导睡眠图检查中呼吸暂停-低通气指数的影响
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-12-18 DOI: 10.1007/s11818-023-00438-z
Joachim T. Maurer, Merle Gasparic, Jamal Huseynov
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引用次数: 0
Diagnostische Aussagekraft des Berlin-Fragebogens bei Patienten mit intrakraniellen Aneurysmata 柏林问卷对颅内动脉瘤患者的诊断意义
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-12-05 DOI: 10.1007/s11818-023-00437-0
S. Zaremba, L. Albus, H. Vatter, U. Wüllner, Erdem Güresir
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引用次数: 0
Schlaf im Wandel 过渡时期的睡眠
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-23 DOI: 10.1007/s11818-023-00433-4
Thomas Penzel, H. Danker-Hopfe, Ingo Fietze
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引用次数: 0
Durchführung und Interpretation des multiplen Schlaflatenztests (MSLT) bei Erwachsenen 执行和解释成年人的多睡眠障碍检查
Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-10 DOI: 10.1007/s11818-023-00431-6
Christian Veauthier, Ulf Kallweit, Hartmut Schulz, Johannes Mathis, Peter Geisler, Sebastian Zaremba, Renata N. B. de Almeida Schreck, Andrea Hillberg, Anelia Todorova-Rudolph, Moritz Brandt, Anna Heidbreder, Geert Mayer
Zusammenfassung Der multiple Schlaflatenztest (MSLT) ist ein diagnostisches Instrument zur objektiven Bestimmung der Einschlafneigung am Tage. Er dient der Differentialdiagnostik der Narkolepsie, Hypersomnie und anderen Erkrankungen mit gesteigerter Tagesschläfrigkeit. Mittels Elektroenzephalographie, Elektromyographie des Kinns und Elektrookulographie werden in diesem Einschlaftest die durchschnittliche Einschlaflatenz sowie das Auftreten von REM-Schlaf, unter idealen Schlafbedingungen in einem abgedunkelten Raum mit der Aufforderung einzuschlafen, gemessen. Er wird tagsüber nach einer Polysomnographie in der vorausgehenden Nacht durchgeführt und besteht aus fünf standardisierten Testdurchgängen im Abstand von jeweils zwei Stunden. Medikamente, Schlafentzug sowie stimulierende Substanzen oder Aktivitäten können die Ergebnisse des Tests beeinflussen. Im Jahr 2021 wurde die MSLT-Leitlinie seitens der American Academy of Sleep Medicine (AASM) aktualisiert. Der vorliegende Artikel stellt die aktualisierte Richtlinie vor und kommentiert diese.
多发性睡眠性呼吸暂停(mlt)是一种诊断工具以客观评估当天的睡眠状态。诊断学是为嗜睡症、低血压和其它症状提供的。在睡眠测试中,用脑电图、脑电图和电瓶仪对正常的睡眠情况和在充满挑战的封闭空间中睡眠的正常情况下的快速睡眠情况进行测量。此项测试将在之前的晚测之后,在白天进行,并由五个标准测试间隔两个小时组成。药物、不睡眠和刺激物质或活动都可以影响测试结果。比方说,2021年,美国睡眠医学学院更新了msl规范。本文章提出了更新的政策,并对其进行评论。
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引用次数: 0
Messung des Atemzugvolumens bei Patienten mit Obesitas-Hypoventilations-Syndrom und Opiumabhängigkeit 测量奥氏综合症病人呼吸急促及鸦片依赖程度
Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-09 DOI: 10.1007/s11818-023-00434-3
Babak Amra, Bahar Behvandi, Forogh Soltaninejad, Mehrzad Salmasi, Awat Feizi, Martin Glos, Ingo Fietze, Thomas Penzel, Matthew Salanitro
Abstract Background Both obesity hypoventilation syndrome (OHS) and opium dependence can negatively affect nocturnal respiratory functionality. However, the effects of a combination of the two are relatively unknown. In this study, the tidal volume (VT) of OHS patients with and without opium dependence was estimated by measuring changes in the circumference of the thorax and the abdomen during sleep. Materials and methods This case–control study was performed in Iran, Isfahan. Initially, 20 healthy subjects calibrated the Pneumobelts (Löwenstein Medical Technology GmbH, Hamburg, Germany) by wearing the device and also breathing in and out of a Spirobag. From this, it was possible to estimate the coefficient factors for determining VT based on thoracic and abdominal measures. Subsequently, the study included 55 patients with OHS, who were divided into two groups: opium dependent and non-users. They were then admitted to the sleep lab for a single night of polysomnography (PSG). VT was estimated and then compared between groups. Results In total, there were 24 patients in the opium group and 31 in the non-user control group. All PSG variables were analyzed with independent-sample t -tests and an analysis of covariance was used to adjust for potential confounding variables. The following confounding variables were adjusted: sex, smoking, body mass index, and hypertension. VT values were not significantly different between groups (opium: 772 ± 125.4; non-user: 774 ± 95). Average oxygen saturation values were significantly lower in opium-dependent patients (opium: 86.1 ± 5.5; non-user: 89.1 ± 4.1). All other variables from PSG including chest and abdominal circumference were not significantly different between groups. Conclusion OHS patients with opium dependency showed similar VT levels when compared to non-users with OHS. Due to the rarity of the sample, it was difficult to gather exactly matched pairs. Therefore, it is possible that with a more closely related sample, we might be able to see a difference in VT between groups.
背景肥胖低通气综合征(OHS)和鸦片依赖均可对夜间呼吸功能产生负面影响。然而,两者结合的影响相对未知。本研究通过测量睡眠时胸腹围度的变化来估计有鸦片依赖和无鸦片依赖的OHS患者的潮气量(VT)。材料和方法本病例对照研究在伊朗伊斯法罕进行。最初,20名健康受试者通过佩戴该设备并通过吸入和呼出Spirobag来校准气垫(Löwenstein Medical Technology GmbH, Hamburg, Germany)。由此,可以根据胸腹测量来估计决定VT的系数因子。随后,该研究纳入了55名OHS患者,他们被分为两组:鸦片依赖和非使用者。然后他们被送入睡眠实验室进行一晚的多导睡眠描记(PSG)。评估各组间VT并进行比较。结果鸦片治疗组24例,非鸦片治疗组31例。所有PSG变量均采用独立样本t检验进行分析,并采用协方差分析来调整潜在的混杂变量。调整了以下混杂变量:性别、吸烟、体重指数和高血压。各组间VT值无显著差异(鸦片:772±125.4;非用户:774±95)。阿片依赖患者的平均血氧饱和度明显降低(阿片:86.1±5.5;非用户:89.1±4.1)。包括胸围和腹围在内的所有其他PSG变量在组间无显著差异。结论鸦片依赖OHS患者与非鸦片依赖OHS患者的VT水平相似。由于样本的稀缺性,很难收集到完全匹配的配对。因此,有可能通过更密切相关的样本,我们可能能够看到组间VT的差异。
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引用次数: 1
Sekundäre obstruktive Schlafapnoe 第二性睡眠障碍
Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-09 DOI: 10.1007/s11818-023-00430-7
Richard Schulz, Edyta Schulz
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引用次数: 0
Does daylight saving time lead to more myocardial infarctions? 夏令时是否会导致更多的心肌梗死?
Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-01 DOI: 10.1007/s11818-023-00429-0
Adel Fansa, Ingo Fietze, Thomas Penzel, Sebastian Herberger
Abstract Background Daylight saving time (DST) is practiced in over 70 countries worldwide. Its assumed economic benefits have become subject of increasing controversy in the recent past, and, together with its likely negative impacts on health, have led to the decision to abolish DST in the EU and the USA. Transitions from and to DST disrupt the circadian rhythm and lead to measurable adverse effects. Among them, the incidence of acute myocardial infarction (AMI) is suspected to increase as a consequence of DST changes. Objective The aim of this study is to examine the relationship between DST transitions and the incidence of acute myocardial infarction based on the available literature. Materials and methods A systematic literature search in the MEDLINE database was performed. Studies were included that observed the AMI incidence after transitioning from or to DST and had a control period beyond or around the post-transitional weeks. Of 26 identified studies, 8 met the inclusion criteria. Results were interpreted with an emphasis on methodological differences, reported incidence rates, and subgroup analyses. Results Seven of the identified studies reported the incidence rate ratio (IRR), observed-to-expected ratio, or odds ratio, while one study only reported IRR values for the individual days and statistical significance levels for the transition weeks. Six studies reported an increased incidence after the spring shift, four of which were statistically significant. Three studies reported an increase after the autumn shift, of which two were statistically significant. Conclusion Several studies show increased AMI incidence rates following both spring and autumn DST shifts, yet results remain in part contradictory. Future research to establish a better understanding of the health implications of DST transitions is warranted, and the quantification of incidence rates should control for confounding factors.
摘要背景日光节约时间(DST)在全球70多个国家实行。在最近的过去,其假定的经济效益已经成为越来越有争议的主题,并且连同其可能对健康的负面影响,已经导致欧盟和美国决定废除夏时制。从夏时制到夏时制的过渡会破坏昼夜节律,并导致可测量的不利影响。其中,急性心肌梗死(AMI)的发生率可能因DST改变而增加。目的在现有文献的基础上,探讨DST转换与急性心肌梗死发生率之间的关系。材料与方法在MEDLINE数据库中进行系统的文献检索。研究纳入了观察从DST过渡或过渡到DST后AMI发生率的研究,并在过渡后几周或前后有一个控制期。在确定的26项研究中,有8项符合纳入标准。对结果进行了解释,重点放在方法学差异、报告发病率和亚组分析上。7项研究报告了发病率比(IRR)、观察-预期比或优势比,而1项研究仅报告了个别天数的IRR值和过渡周的统计显著性水平。6项研究报告了春季换班后发病率增加,其中4项具有统计学意义。三项研究报告称,在秋季换班后,发病率有所上升,其中两项具有统计学意义。结论:一些研究表明,春季和秋季夏令时改变后AMI发病率都增加,但结果在一定程度上仍然是矛盾的。未来的研究是有必要的,以更好地了解DST转换对健康的影响,并且发病率的量化应该控制混杂因素。
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引用次数: 1
Sleep apnea healthcare management in dynamically changing times 动态变化时代的睡眠呼吸暂停保健管理
Q4 CLINICAL NEUROLOGY Pub Date : 2023-10-25 DOI: 10.1007/s11818-023-00428-1
Dagmar Krefting, Michael Arzt, Joachim T Maurer, Thomas Penzel, Fabian Prasser, Martin Sedlmayr, Christoph Schöbel
Abstract Background Obstructive sleep apnea (OSA) is a common chronic disorder and an independent risk factor for several health issues, with a high prevalence estimated at 30% for men and 13% for women in Germany. Objective For both individual wellbeing and healthcare systems, efficient and effective diagnosis and treatment of OSA are essential. Actors and stations along the patient pathway that may strongly benefit from adoption of current and evolving digital methods and tools are to be identified. Materials and methods This work analyzes an OSA patient’s pathway through the German healthcare system, as well as current developments in health informatics and patient involvement. Potential benefits are identified and a patient-centric integrated digital health system is conceptualized. Results Digital health strategies of German and European governments emphasize the importance of connected healthcare for patient empowerment, efficient health systems, and innovations in healthcare. For OSA, in particular intersectoral sharing of health assessments and biosignal measurements can support physicians’ care and timely and adequate treatment. Furthermore, clinical decision-support systems including artificial intelligence may help in optimized patient-centric treatment by early detection of females suffering from OSA, OSA pheno- and endotypes, and patients at risk of abandoning treatments. However, bureaucratic and reimbursement barriers in legislation may slow down or even inhibit the implementation of a smart healthcare system. Conclusion Current trends in connected digital healthcare, wearables, data-driven decision support, and patient participation offer many opportunities for significantly improving healthcare for OSA. However, many technical, organizational, and regulatory challenges are to be faced.
背景:阻塞性睡眠呼吸暂停(OSA)是一种常见的慢性疾病,也是多种健康问题的独立危险因素,在德国,男性和女性的患病率分别高达30%和13%。目的对个体健康和医疗保健系统而言,高效、有效的OSA诊断和治疗至关重要。将确定可能从采用当前和不断发展的数字方法和工具中获益的患者路径上的参与者和站点。材料和方法本研究分析了一位OSA患者通过德国医疗保健系统的途径,以及健康信息学和患者参与的最新发展。确定了潜在的好处,并对以患者为中心的综合数字卫生系统进行了概念化。结果:德国和欧洲各国政府的数字健康战略强调了互联医疗对患者赋权、高效医疗系统和医疗创新的重要性。对于阻塞性睡眠呼吸暂停症,特别是部门间共享健康评估和生物信号测量可以支持医生的护理和及时和充分的治疗。此外,包括人工智能在内的临床决策支持系统可能有助于优化以患者为中心的治疗,通过早期发现女性OSA, OSA现象型和内源性,以及有放弃治疗风险的患者。然而,立法中的官僚主义和报销障碍可能会减缓甚至抑制智能医疗保健系统的实施。结论互联数字医疗、可穿戴设备、数据驱动决策支持和患者参与的当前趋势为显著改善OSA的医疗保健提供了许多机会。然而,许多技术、组织和监管方面的挑战将面临。
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引用次数: 1
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Somnologie
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