Pub Date : 2023-12-19DOI: 10.1007/s11818-023-00435-2
Holger Woehrle, M. Arzt, J. Ficker, Melike Deger, Kimberly L. Sterling, Daniela Ehrsam-Tosi, T. Vogelmann, Sina Weinand, Ingo Fietze, Peter M. Young, C. Schoebel
{"title":"Prävalenz und Prädiktoren der positiven Atemwegsdrucktherapie bei obstruktiver Schlafapnoe: eine bevölkerungsrepräsentative Studie","authors":"Holger Woehrle, M. Arzt, J. Ficker, Melike Deger, Kimberly L. Sterling, Daniela Ehrsam-Tosi, T. Vogelmann, Sina Weinand, Ingo Fietze, Peter M. Young, C. Schoebel","doi":"10.1007/s11818-023-00435-2","DOIUrl":"https://doi.org/10.1007/s11818-023-00435-2","url":null,"abstract":"","PeriodicalId":21947,"journal":{"name":"Somnologie","volume":" 6","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138961839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.1007/s11818-023-00438-z
Joachim T. Maurer, Merle Gasparic, Jamal Huseynov
{"title":"Impact of the timing of drug-induced sleep endoscopy on the apnea–hypopnea index during polysomnography","authors":"Joachim T. Maurer, Merle Gasparic, Jamal Huseynov","doi":"10.1007/s11818-023-00438-z","DOIUrl":"https://doi.org/10.1007/s11818-023-00438-z","url":null,"abstract":"","PeriodicalId":21947,"journal":{"name":"Somnologie","volume":"44 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139174137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-05DOI: 10.1007/s11818-023-00437-0
S. Zaremba, L. Albus, H. Vatter, U. Wüllner, Erdem Güresir
{"title":"Diagnostische Aussagekraft des Berlin-Fragebogens bei Patienten mit intrakraniellen Aneurysmata","authors":"S. Zaremba, L. Albus, H. Vatter, U. Wüllner, Erdem Güresir","doi":"10.1007/s11818-023-00437-0","DOIUrl":"https://doi.org/10.1007/s11818-023-00437-0","url":null,"abstract":"","PeriodicalId":21947,"journal":{"name":"Somnologie","volume":"9 2","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138601227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-10DOI: 10.1007/s11818-023-00431-6
Christian Veauthier, Ulf Kallweit, Hartmut Schulz, Johannes Mathis, Peter Geisler, Sebastian Zaremba, Renata N. B. de Almeida Schreck, Andrea Hillberg, Anelia Todorova-Rudolph, Moritz Brandt, Anna Heidbreder, Geert Mayer
Zusammenfassung Der multiple Schlaflatenztest (MSLT) ist ein diagnostisches Instrument zur objektiven Bestimmung der Einschlafneigung am Tage. Er dient der Differentialdiagnostik der Narkolepsie, Hypersomnie und anderen Erkrankungen mit gesteigerter Tagesschläfrigkeit. Mittels Elektroenzephalographie, Elektromyographie des Kinns und Elektrookulographie werden in diesem Einschlaftest die durchschnittliche Einschlaflatenz sowie das Auftreten von REM-Schlaf, unter idealen Schlafbedingungen in einem abgedunkelten Raum mit der Aufforderung einzuschlafen, gemessen. Er wird tagsüber nach einer Polysomnographie in der vorausgehenden Nacht durchgeführt und besteht aus fünf standardisierten Testdurchgängen im Abstand von jeweils zwei Stunden. Medikamente, Schlafentzug sowie stimulierende Substanzen oder Aktivitäten können die Ergebnisse des Tests beeinflussen. Im Jahr 2021 wurde die MSLT-Leitlinie seitens der American Academy of Sleep Medicine (AASM) aktualisiert. Der vorliegende Artikel stellt die aktualisierte Richtlinie vor und kommentiert diese.
{"title":"Durchführung und Interpretation des multiplen Schlaflatenztests (MSLT) bei Erwachsenen","authors":"Christian Veauthier, Ulf Kallweit, Hartmut Schulz, Johannes Mathis, Peter Geisler, Sebastian Zaremba, Renata N. B. de Almeida Schreck, Andrea Hillberg, Anelia Todorova-Rudolph, Moritz Brandt, Anna Heidbreder, Geert Mayer","doi":"10.1007/s11818-023-00431-6","DOIUrl":"https://doi.org/10.1007/s11818-023-00431-6","url":null,"abstract":"Zusammenfassung Der multiple Schlaflatenztest (MSLT) ist ein diagnostisches Instrument zur objektiven Bestimmung der Einschlafneigung am Tage. Er dient der Differentialdiagnostik der Narkolepsie, Hypersomnie und anderen Erkrankungen mit gesteigerter Tagesschläfrigkeit. Mittels Elektroenzephalographie, Elektromyographie des Kinns und Elektrookulographie werden in diesem Einschlaftest die durchschnittliche Einschlaflatenz sowie das Auftreten von REM-Schlaf, unter idealen Schlafbedingungen in einem abgedunkelten Raum mit der Aufforderung einzuschlafen, gemessen. Er wird tagsüber nach einer Polysomnographie in der vorausgehenden Nacht durchgeführt und besteht aus fünf standardisierten Testdurchgängen im Abstand von jeweils zwei Stunden. Medikamente, Schlafentzug sowie stimulierende Substanzen oder Aktivitäten können die Ergebnisse des Tests beeinflussen. Im Jahr 2021 wurde die MSLT-Leitlinie seitens der American Academy of Sleep Medicine (AASM) aktualisiert. Der vorliegende Artikel stellt die aktualisierte Richtlinie vor und kommentiert diese.","PeriodicalId":21947,"journal":{"name":"Somnologie","volume":"89 24","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135091749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-09DOI: 10.1007/s11818-023-00434-3
Babak Amra, Bahar Behvandi, Forogh Soltaninejad, Mehrzad Salmasi, Awat Feizi, Martin Glos, Ingo Fietze, Thomas Penzel, Matthew Salanitro
Abstract Background Both obesity hypoventilation syndrome (OHS) and opium dependence can negatively affect nocturnal respiratory functionality. However, the effects of a combination of the two are relatively unknown. In this study, the tidal volume (VT) of OHS patients with and without opium dependence was estimated by measuring changes in the circumference of the thorax and the abdomen during sleep. Materials and methods This case–control study was performed in Iran, Isfahan. Initially, 20 healthy subjects calibrated the Pneumobelts (Löwenstein Medical Technology GmbH, Hamburg, Germany) by wearing the device and also breathing in and out of a Spirobag. From this, it was possible to estimate the coefficient factors for determining VT based on thoracic and abdominal measures. Subsequently, the study included 55 patients with OHS, who were divided into two groups: opium dependent and non-users. They were then admitted to the sleep lab for a single night of polysomnography (PSG). VT was estimated and then compared between groups. Results In total, there were 24 patients in the opium group and 31 in the non-user control group. All PSG variables were analyzed with independent-sample t -tests and an analysis of covariance was used to adjust for potential confounding variables. The following confounding variables were adjusted: sex, smoking, body mass index, and hypertension. VT values were not significantly different between groups (opium: 772 ± 125.4; non-user: 774 ± 95). Average oxygen saturation values were significantly lower in opium-dependent patients (opium: 86.1 ± 5.5; non-user: 89.1 ± 4.1). All other variables from PSG including chest and abdominal circumference were not significantly different between groups. Conclusion OHS patients with opium dependency showed similar VT levels when compared to non-users with OHS. Due to the rarity of the sample, it was difficult to gather exactly matched pairs. Therefore, it is possible that with a more closely related sample, we might be able to see a difference in VT between groups.
背景肥胖低通气综合征(OHS)和鸦片依赖均可对夜间呼吸功能产生负面影响。然而,两者结合的影响相对未知。本研究通过测量睡眠时胸腹围度的变化来估计有鸦片依赖和无鸦片依赖的OHS患者的潮气量(VT)。材料和方法本病例对照研究在伊朗伊斯法罕进行。最初,20名健康受试者通过佩戴该设备并通过吸入和呼出Spirobag来校准气垫(Löwenstein Medical Technology GmbH, Hamburg, Germany)。由此,可以根据胸腹测量来估计决定VT的系数因子。随后,该研究纳入了55名OHS患者,他们被分为两组:鸦片依赖和非使用者。然后他们被送入睡眠实验室进行一晚的多导睡眠描记(PSG)。评估各组间VT并进行比较。结果鸦片治疗组24例,非鸦片治疗组31例。所有PSG变量均采用独立样本t检验进行分析,并采用协方差分析来调整潜在的混杂变量。调整了以下混杂变量:性别、吸烟、体重指数和高血压。各组间VT值无显著差异(鸦片:772±125.4;非用户:774±95)。阿片依赖患者的平均血氧饱和度明显降低(阿片:86.1±5.5;非用户:89.1±4.1)。包括胸围和腹围在内的所有其他PSG变量在组间无显著差异。结论鸦片依赖OHS患者与非鸦片依赖OHS患者的VT水平相似。由于样本的稀缺性,很难收集到完全匹配的配对。因此,有可能通过更密切相关的样本,我们可能能够看到组间VT的差异。
{"title":"Messung des Atemzugvolumens bei Patienten mit Obesitas-Hypoventilations-Syndrom und Opiumabhängigkeit","authors":"Babak Amra, Bahar Behvandi, Forogh Soltaninejad, Mehrzad Salmasi, Awat Feizi, Martin Glos, Ingo Fietze, Thomas Penzel, Matthew Salanitro","doi":"10.1007/s11818-023-00434-3","DOIUrl":"https://doi.org/10.1007/s11818-023-00434-3","url":null,"abstract":"Abstract Background Both obesity hypoventilation syndrome (OHS) and opium dependence can negatively affect nocturnal respiratory functionality. However, the effects of a combination of the two are relatively unknown. In this study, the tidal volume (VT) of OHS patients with and without opium dependence was estimated by measuring changes in the circumference of the thorax and the abdomen during sleep. Materials and methods This case–control study was performed in Iran, Isfahan. Initially, 20 healthy subjects calibrated the Pneumobelts (Löwenstein Medical Technology GmbH, Hamburg, Germany) by wearing the device and also breathing in and out of a Spirobag. From this, it was possible to estimate the coefficient factors for determining VT based on thoracic and abdominal measures. Subsequently, the study included 55 patients with OHS, who were divided into two groups: opium dependent and non-users. They were then admitted to the sleep lab for a single night of polysomnography (PSG). VT was estimated and then compared between groups. Results In total, there were 24 patients in the opium group and 31 in the non-user control group. All PSG variables were analyzed with independent-sample t -tests and an analysis of covariance was used to adjust for potential confounding variables. The following confounding variables were adjusted: sex, smoking, body mass index, and hypertension. VT values were not significantly different between groups (opium: 772 ± 125.4; non-user: 774 ± 95). Average oxygen saturation values were significantly lower in opium-dependent patients (opium: 86.1 ± 5.5; non-user: 89.1 ± 4.1). All other variables from PSG including chest and abdominal circumference were not significantly different between groups. Conclusion OHS patients with opium dependency showed similar VT levels when compared to non-users with OHS. Due to the rarity of the sample, it was difficult to gather exactly matched pairs. Therefore, it is possible that with a more closely related sample, we might be able to see a difference in VT between groups.","PeriodicalId":21947,"journal":{"name":"Somnologie","volume":" 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135291074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.1007/s11818-023-00429-0
Adel Fansa, Ingo Fietze, Thomas Penzel, Sebastian Herberger
Abstract Background Daylight saving time (DST) is practiced in over 70 countries worldwide. Its assumed economic benefits have become subject of increasing controversy in the recent past, and, together with its likely negative impacts on health, have led to the decision to abolish DST in the EU and the USA. Transitions from and to DST disrupt the circadian rhythm and lead to measurable adverse effects. Among them, the incidence of acute myocardial infarction (AMI) is suspected to increase as a consequence of DST changes. Objective The aim of this study is to examine the relationship between DST transitions and the incidence of acute myocardial infarction based on the available literature. Materials and methods A systematic literature search in the MEDLINE database was performed. Studies were included that observed the AMI incidence after transitioning from or to DST and had a control period beyond or around the post-transitional weeks. Of 26 identified studies, 8 met the inclusion criteria. Results were interpreted with an emphasis on methodological differences, reported incidence rates, and subgroup analyses. Results Seven of the identified studies reported the incidence rate ratio (IRR), observed-to-expected ratio, or odds ratio, while one study only reported IRR values for the individual days and statistical significance levels for the transition weeks. Six studies reported an increased incidence after the spring shift, four of which were statistically significant. Three studies reported an increase after the autumn shift, of which two were statistically significant. Conclusion Several studies show increased AMI incidence rates following both spring and autumn DST shifts, yet results remain in part contradictory. Future research to establish a better understanding of the health implications of DST transitions is warranted, and the quantification of incidence rates should control for confounding factors.
{"title":"Does daylight saving time lead to more myocardial infarctions?","authors":"Adel Fansa, Ingo Fietze, Thomas Penzel, Sebastian Herberger","doi":"10.1007/s11818-023-00429-0","DOIUrl":"https://doi.org/10.1007/s11818-023-00429-0","url":null,"abstract":"Abstract Background Daylight saving time (DST) is practiced in over 70 countries worldwide. Its assumed economic benefits have become subject of increasing controversy in the recent past, and, together with its likely negative impacts on health, have led to the decision to abolish DST in the EU and the USA. Transitions from and to DST disrupt the circadian rhythm and lead to measurable adverse effects. Among them, the incidence of acute myocardial infarction (AMI) is suspected to increase as a consequence of DST changes. Objective The aim of this study is to examine the relationship between DST transitions and the incidence of acute myocardial infarction based on the available literature. Materials and methods A systematic literature search in the MEDLINE database was performed. Studies were included that observed the AMI incidence after transitioning from or to DST and had a control period beyond or around the post-transitional weeks. Of 26 identified studies, 8 met the inclusion criteria. Results were interpreted with an emphasis on methodological differences, reported incidence rates, and subgroup analyses. Results Seven of the identified studies reported the incidence rate ratio (IRR), observed-to-expected ratio, or odds ratio, while one study only reported IRR values for the individual days and statistical significance levels for the transition weeks. Six studies reported an increased incidence after the spring shift, four of which were statistically significant. Three studies reported an increase after the autumn shift, of which two were statistically significant. Conclusion Several studies show increased AMI incidence rates following both spring and autumn DST shifts, yet results remain in part contradictory. Future research to establish a better understanding of the health implications of DST transitions is warranted, and the quantification of incidence rates should control for confounding factors.","PeriodicalId":21947,"journal":{"name":"Somnologie","volume":"30 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135325531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-25DOI: 10.1007/s11818-023-00428-1
Dagmar Krefting, Michael Arzt, Joachim T Maurer, Thomas Penzel, Fabian Prasser, Martin Sedlmayr, Christoph Schöbel
Abstract Background Obstructive sleep apnea (OSA) is a common chronic disorder and an independent risk factor for several health issues, with a high prevalence estimated at 30% for men and 13% for women in Germany. Objective For both individual wellbeing and healthcare systems, efficient and effective diagnosis and treatment of OSA are essential. Actors and stations along the patient pathway that may strongly benefit from adoption of current and evolving digital methods and tools are to be identified. Materials and methods This work analyzes an OSA patient’s pathway through the German healthcare system, as well as current developments in health informatics and patient involvement. Potential benefits are identified and a patient-centric integrated digital health system is conceptualized. Results Digital health strategies of German and European governments emphasize the importance of connected healthcare for patient empowerment, efficient health systems, and innovations in healthcare. For OSA, in particular intersectoral sharing of health assessments and biosignal measurements can support physicians’ care and timely and adequate treatment. Furthermore, clinical decision-support systems including artificial intelligence may help in optimized patient-centric treatment by early detection of females suffering from OSA, OSA pheno- and endotypes, and patients at risk of abandoning treatments. However, bureaucratic and reimbursement barriers in legislation may slow down or even inhibit the implementation of a smart healthcare system. Conclusion Current trends in connected digital healthcare, wearables, data-driven decision support, and patient participation offer many opportunities for significantly improving healthcare for OSA. However, many technical, organizational, and regulatory challenges are to be faced.
{"title":"Sleep apnea healthcare management in dynamically changing times","authors":"Dagmar Krefting, Michael Arzt, Joachim T Maurer, Thomas Penzel, Fabian Prasser, Martin Sedlmayr, Christoph Schöbel","doi":"10.1007/s11818-023-00428-1","DOIUrl":"https://doi.org/10.1007/s11818-023-00428-1","url":null,"abstract":"Abstract Background Obstructive sleep apnea (OSA) is a common chronic disorder and an independent risk factor for several health issues, with a high prevalence estimated at 30% for men and 13% for women in Germany. Objective For both individual wellbeing and healthcare systems, efficient and effective diagnosis and treatment of OSA are essential. Actors and stations along the patient pathway that may strongly benefit from adoption of current and evolving digital methods and tools are to be identified. Materials and methods This work analyzes an OSA patient’s pathway through the German healthcare system, as well as current developments in health informatics and patient involvement. Potential benefits are identified and a patient-centric integrated digital health system is conceptualized. Results Digital health strategies of German and European governments emphasize the importance of connected healthcare for patient empowerment, efficient health systems, and innovations in healthcare. For OSA, in particular intersectoral sharing of health assessments and biosignal measurements can support physicians’ care and timely and adequate treatment. Furthermore, clinical decision-support systems including artificial intelligence may help in optimized patient-centric treatment by early detection of females suffering from OSA, OSA pheno- and endotypes, and patients at risk of abandoning treatments. However, bureaucratic and reimbursement barriers in legislation may slow down or even inhibit the implementation of a smart healthcare system. Conclusion Current trends in connected digital healthcare, wearables, data-driven decision support, and patient participation offer many opportunities for significantly improving healthcare for OSA. However, many technical, organizational, and regulatory challenges are to be faced.","PeriodicalId":21947,"journal":{"name":"Somnologie","volume":"85 3-4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}