Introduction: Primary open-angle glaucoma (POAG) is a subset of glaucoma defined by an open, normal-appearing anterior chamber angle and raised intraocular pressure (IOP) with no other underlying disease. Globally 57.5 million people were affected by primary open-angle glaucoma (POAG) in 2015, rising to 65.5 million by 2020. POAG can further lead to optic nerve damage, which can cause total blindness. POAG cannot be cured but can be controlled with medical therapy, laser, and surgical procedures. Antiglaucoma drugs are a method of treatment that can overcome this disease. This study aims to determine the characteristics of patients with POAG and progressivity of cup to disc ratio and intraocular pressure after 3 months of management of 2 antiglaucoma agents in POAG patients in Dr. Mohammad Hoesin General Hospital Palembang. Methods: This study retrospectively reviewed the medical records specific to primary open-angle glaucoma. Data was obtained from the patient register book recorded from February 2022 to May 2022 in Dr. Mohammad Hoesin General Hospital Palembang. The parameters analyzed were patients' profiles, namely gender, intraocular pressure, and cup to disc ratio before and after 3 months of combination 2 antiglaucoma agents. Timolol and latanoprost are the 2 antiglaucoma agents given to patients diagnosed of previous POAG (by an ophthalmologist). Results: From 30 patients diagnosed with POAG by an ophthalmologist, the number of primary open-angle glaucoma patients was more female, namely 19 patients (63.3%) than 11 male patients (36.7%), with a ratio of 1.28:1 between women and men. The cup to disc ratio between before and after 3 months of therapy using timolol and latanoprost was 0.628 ± 0.04 before therapy to 0.645 ± 0.06 after therapy (p<0.05). Intraocular pressure before and after 3 months of therapy was 24.76 ± 2.63 before therapy to 17.75 ± 2.08 (p<0,05). Both cup to disc ratio and intraocular pressure differs statistically from before and after therapy. Conclusion: Fixed combination therapy of timolol and latanoprost is effective in lowering intraocular pressure and reducing cup to disc ratio progressivity in patients with primary open-angle glaucoma.
原发性开角型青光眼(POAG)是青光眼的一个亚群，其定义为前房角开放，外观正常，眼压(IOP)升高，无其他基础疾病。2015年，全球有5750万人患有原发性开角型青光眼(POAG)，到2020年将增加到6550万人。POAG会进一步导致视神经损伤，从而导致完全失明。POAG不能治愈，但可以通过药物治疗、激光和外科手术来控制。抗青光眼药物是一种可以克服这种疾病的治疗方法。本研究旨在确定POAG患者的特征，以及在Palembang的Dr. Mohammad Hoesin综合医院治疗2种抗青光眼药物3个月后POAG患者杯盘比和眼压的进展。方法:回顾性分析原发性开角型青光眼的临床资料。数据来自2022年2月至2022年5月在巨港穆罕默德·胡辛综合医院记录的患者登记簿。分析的参数为患者在联合2种抗青光眼药物治疗3个月前后的性别、眼压、杯盘比。替马洛尔和拉坦前列素是两种抗青光眼药物，给予诊断为既往POAG的患者(由眼科医生)。结果:在30例经眼科医生诊断为POAG的患者中，原发性开角型青光眼患者女性较多，女性19例(63.3%)，男性11例(36.7%)，男女之比为1.28:1。替洛尔和拉坦前列素治疗3个月前后杯盘比分别为治疗前0.628±0.04和治疗后0.645±0.06 (p<0.05)。治疗前和治疗后3个月眼压分别为24.76±2.63和17.75±2.08 (p< 0.05)。治疗前后杯盘比和眼压均有统计学差异。结论:替洛尔联合拉坦前列素固定联合治疗原发性开角型青光眼可有效降低眼压，减少杯盘比进展。
{"title":"Relationship between Progressive Cup Disc Ratio and Intraocular Pressure in Primary Open Angle Glaucoma After 2 Antiglaucoma Agents for 3 Months","authors":"M. F. Syafridon, Fidalia, Prima Maya Sari","doi":"10.37275/sjo.v6i1.77","DOIUrl":"https://doi.org/10.37275/sjo.v6i1.77","url":null,"abstract":"Introduction: Primary open-angle glaucoma (POAG) is a subset of glaucoma defined by an open, normal-appearing anterior chamber angle and raised intraocular pressure (IOP) with no other underlying disease. Globally 57.5 million people were affected by primary open-angle glaucoma (POAG) in 2015, rising to 65.5 million by 2020. POAG can further lead to optic nerve damage, which can cause total blindness. POAG cannot be cured but can be controlled with medical therapy, laser, and surgical procedures. Antiglaucoma drugs are a method of treatment that can overcome this disease. This study aims to determine the characteristics of patients with POAG and progressivity of cup to disc ratio and intraocular pressure after 3 months of management of 2 antiglaucoma agents in POAG patients in Dr. Mohammad Hoesin General Hospital Palembang. Methods: This study retrospectively reviewed the medical records specific to primary open-angle glaucoma. Data was obtained from the patient register book recorded from February 2022 to May 2022 in Dr. Mohammad Hoesin General Hospital Palembang. The parameters analyzed were patients' profiles, namely gender, intraocular pressure, and cup to disc ratio before and after 3 months of combination 2 antiglaucoma agents. Timolol and latanoprost are the 2 antiglaucoma agents given to patients diagnosed of previous POAG (by an ophthalmologist). Results: From 30 patients diagnosed with POAG by an ophthalmologist, the number of primary open-angle glaucoma patients was more female, namely 19 patients (63.3%) than 11 male patients (36.7%), with a ratio of 1.28:1 between women and men. The cup to disc ratio between before and after 3 months of therapy using timolol and latanoprost was 0.628 ± 0.04 before therapy to 0.645 ± 0.06 after therapy (p<0.05). Intraocular pressure before and after 3 months of therapy was 24.76 ± 2.63 before therapy to 17.75 ± 2.08 (p<0,05). Both cup to disc ratio and intraocular pressure differs statistically from before and after therapy. Conclusion: Fixed combination therapy of timolol and latanoprost is effective in lowering intraocular pressure and reducing cup to disc ratio progressivity in patients with primary open-angle glaucoma.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"43 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91402032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Myopia is a clinical condition that occurs when the image of a distant object is focused in front of the retina by the non-accommodating eye. The prevalence of Myopia has been getting higher for decades. A cohort study stated continuing axial elongation in adults with high Myopia. Methods: This research is a retrospective study approach. Data obtained from central general hospital Dr. Mohammad Hoesin Palembang from January 2021 to February 2022. Medical record data included in this study were patients diagnosed as myopic patients. The exclusion criteria were patients with missing medical records and any other refractive disorder. The correlation between myopia degree and axial length using ANOVA or Kruskal-Wallis H test depend on its data distribution. Data processing was performed using SPSS version 25. This study aims to determine the association between axial length and myopia degree. Results: Female patients are found predominantly (58.5%). Through the recent surveys, either the domestic or foreign population, results have stated that the prevalence of Myopia is higher in females, and other studies found that it fluctuated with age among adolescent females. The age of patients varies from 16 years to 75 years, and the mean baseline is 30.9± 3.82 years. Mild Myopia accounts most common incidence (53.1%), with laterality, which is found to be more common in the left eye (57.1%). Mean baseline axial length 21.95± 2.85 with visual acuity in LogMar 0.89 ± 0.51. There is a statistically significant difference in axial length based on myopia degree (p=0.000). Conclusion: Female patients are found predominantly in myopia patients, with the age of patients varying from 16 years to 75 years and a mean baseline of 30.9± 3.82 years. There is a statistically significant difference in axial length based on myopia degree.
{"title":"Association of Axial Length and Myopia Degree: A Retrospective Study","authors":"Syena Damara, Aniz Ismail","doi":"10.37275/sjo.v5i2.70","DOIUrl":"https://doi.org/10.37275/sjo.v5i2.70","url":null,"abstract":"Introduction: Myopia is a clinical condition that occurs when the image of a distant object is focused in front of the retina by the non-accommodating eye. The prevalence of Myopia has been getting higher for decades. A cohort study stated continuing axial elongation in adults with high Myopia. \u0000Methods: This research is a retrospective study approach. Data obtained from central general hospital Dr. Mohammad Hoesin Palembang from January 2021 to February 2022. Medical record data included in this study were patients diagnosed as myopic patients. The exclusion criteria were patients with missing medical records and any other refractive disorder. The correlation between myopia degree and axial length using ANOVA or Kruskal-Wallis H test depend on its data distribution. Data processing was performed using SPSS version 25. This study aims to determine the association between axial length and myopia degree. \u0000Results: Female patients are found predominantly (58.5%). Through the recent surveys, either the domestic or foreign population, results have stated that the prevalence of Myopia is higher in females, and other studies found that it fluctuated with age among adolescent females. The age of patients varies from 16 years to 75 years, and the mean baseline is 30.9± 3.82 years. Mild Myopia accounts most common incidence (53.1%), with laterality, which is found to be more common in the left eye (57.1%). Mean baseline axial length 21.95± 2.85 with visual acuity in LogMar 0.89 ± 0.51. There is a statistically significant difference in axial length based on myopia degree (p=0.000). \u0000Conclusion: Female patients are found predominantly in myopia patients, with the age of patients varying from 16 years to 75 years and a mean baseline of 30.9± 3.82 years. There is a statistically significant difference in axial length based on myopia degree.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89257474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Blepharoptosis is drooping of the upper eyelid in a primary position, causing the narrowing of the palpebral fissure. This condition can partially or completely cover the visual axis. Establishing the diagnosis of ptosis requires a comprehensive eye examination, including history taking, physical examination, and examination of the eyelids in ptosis patients. The majority of patients with ptosis require surgery, and clinical characteristics play an important role in classifying the type of ptosis and then formulating a detailed treatment plan strategy so that a better outcome is obtained. Methods: A descriptive retrospective study was conducted from medical records of post-surgical ptosis patients at Dr. Mohammad Hoesin Hospital Palembang from January 2016 to December 2021. The data taken included age, gender, the onset of occurrence, laterality, type of ptosis based on the onset, vertical palpebral fissure (FPV), horizontal palpebral fissure (FPH), margin-reflex distance (MRD), margin limbal distance (MLD), lid lag, bell's phenomenon levator muscle function, type of ptosis surgery and postoperative condition. This study aims to determine the clinical characteristics of patients with ptosis at Dr. Mohammad Hoesin Hospital Palembang. Results: Of the 57 ptosis patients in this study, the majority of patients were male, as many as 32 patients (56.1%) with the age category >40 years, as many as 24 patients (42.1%) with unilateral lateral ptosis as many as 50 patients (87.7%) with the more frequent comparison was the left eye in 29 patients (58%). Acquired ptosis was the most common cause in this study in as many as 46 patients (80.7%), and the most common mechanism of acquired ptosis was neurogenic (33.3%). The majority of patients had no previous surgical history of 41 patients (71.9%), moderate levator function of as many as 42 (73.7%), and frontal suspension surgery technique with synthetic materials as many as 17 (34%) patients. the mean FPV was 5.08±2.627 with a median of 5.00 (0-11), FPH 25.94±1.726 with a median of 26.00 (20-29), MRD 0.246±1.78 with a median of 0.00 (-4 -5), MLD 4.789±2.801 with a median of 5.00 (-4-11) and LA 7.16±4.083 with a median of 7.00 (0-14). Ptosis patients had negative lid lag in 47 patients (82.5%) and positive bell's phenomenon in 49 patients (86%). The postoperative condition of ptosis patients was satisfactory where there was no recurrence and reoperation of ptosis, postoperative complications as many as 1 (1.8%) patients experienced overcorrection, 6 (10.5%) patients experienced lagophthalmos, and 2 (3.5%) patients had an outcome. asymmetric. Conclusion: Clinical characteristics of ptosis patients can determine the diagnosis and treatment that will be given to the patient.
睑下垂是指上睑在主位下垂，引起睑裂变窄。这种情况可以部分或完全覆盖视觉轴。确定上睑下垂的诊断需要全面的眼部检查，包括病史、体格检查和上睑下垂患者的眼睑检查。大多数上睑下垂患者需要手术治疗，临床特征对上睑下垂的类型进行分类，进而制定详细的治疗方案策略，从而获得较好的治疗效果起着重要作用。方法:对2016年1月至2021年12月在Palembang Dr. Mohammad Hoesin医院进行的手术后上睑下垂患者的医疗记录进行描述性回顾性研究。数据包括年龄、性别、发病、侧边、发病的上睑下垂类型、垂睑裂(FPV)、水平睑裂(FPH)、睑缘反射距离(MRD)、睑缘缘距离(MLD)、眼睑下垂、贝尔现象、提上睑肌功能、上睑手术类型及术后情况。本研究的目的是确定上睑下垂患者的临床特征在穆罕默德·侯赛因医生医院巨港。结果:本组57例上睑下垂患者中，以男性为主，年龄≥40岁的患者多达32例(56.1%)，单侧侧上睑下垂患者多达24例(42.1%)，单侧侧上睑下垂患者多达50例(87.7%)，比较频繁的是左眼29例(58%)。获得性上睑下垂是本研究中最常见的原因，多达46例(80.7%)，获得性上睑下垂最常见的机制是神经源性(33.3%)。多数患者无手术史41例(71.9%)，中度提上睑肌功能者多达42例(73.7%)，采用合成材料的额部悬吊手术技术者多达17例(34%)。平均FPV为5.08±2.627，中位数为5.00 (0-11)，FPH为25.94±1.726，中位数为26.00 (20-29)，MRD为0.246±1.78，中位数为0.00 (-4 -5)，MLD为4.789±2.801，中位数为5.00 (-4-11)，LA为7.16±4.083，中位数为7.00(0-14)。上睑下垂患者眼睑滞后阴性47例(82.5%)，贝尔氏现象阳性49例(86%)。上睑下垂患者术后情况满意，无复发及再上睑下垂，术后并发症1例(1.8%)出现过矫正，6例(10.5%)出现眼球lagophthalmos, 2例(3.5%)出现转归。不对称的。结论:上睑下垂患者的临床特征决定了患者的诊断和治疗。
{"title":"Clinical Characteristics of Post-surgical Ptosis Patients at Dr. Mohammad Hoesin General Hospital Palembang","authors":"Palembang, Fadillah Amrina, R. Erna, E. Iskandar","doi":"10.37275/sjo.v5i2.76","DOIUrl":"https://doi.org/10.37275/sjo.v5i2.76","url":null,"abstract":"Introduction: Blepharoptosis is drooping of the upper eyelid in a primary position, causing the narrowing of the palpebral fissure. This condition can partially or completely cover the visual axis. Establishing the diagnosis of ptosis requires a comprehensive eye examination, including history taking, physical examination, and examination of the eyelids in ptosis patients. The majority of patients with ptosis require surgery, and clinical characteristics play an important role in classifying the type of ptosis and then formulating a detailed treatment plan strategy so that a better outcome is obtained. \u0000Methods: A descriptive retrospective study was conducted from medical records of post-surgical ptosis patients at Dr. Mohammad Hoesin Hospital Palembang from January 2016 to December 2021. The data taken included age, gender, the onset of occurrence, laterality, type of ptosis based on the onset, vertical palpebral fissure (FPV), horizontal palpebral fissure (FPH), margin-reflex distance (MRD), margin limbal distance (MLD), lid lag, bell's phenomenon levator muscle function, type of ptosis surgery and postoperative condition. This study aims to determine the clinical characteristics of patients with ptosis at Dr. Mohammad Hoesin Hospital Palembang. \u0000Results: Of the 57 ptosis patients in this study, the majority of patients were male, as many as 32 patients (56.1%) with the age category >40 years, as many as 24 patients (42.1%) with unilateral lateral ptosis as many as 50 patients (87.7%) with the more frequent comparison was the left eye in 29 patients (58%). Acquired ptosis was the most common cause in this study in as many as 46 patients (80.7%), and the most common mechanism of acquired ptosis was neurogenic (33.3%). The majority of patients had no previous surgical history of 41 patients (71.9%), moderate levator function of as many as 42 (73.7%), and frontal suspension surgery technique with synthetic materials as many as 17 (34%) patients. the mean FPV was 5.08±2.627 with a median of 5.00 (0-11), FPH 25.94±1.726 with a median of 26.00 (20-29), MRD 0.246±1.78 with a median of 0.00 (-4 -5), MLD 4.789±2.801 with a median of 5.00 (-4-11) and LA 7.16±4.083 with a median of 7.00 (0-14). Ptosis patients had negative lid lag in 47 patients (82.5%) and positive bell's phenomenon in 49 patients (86%). The postoperative condition of ptosis patients was satisfactory where there was no recurrence and reoperation of ptosis, postoperative complications as many as 1 (1.8%) patients experienced overcorrection, 6 (10.5%) patients experienced lagophthalmos, and 2 (3.5%) patients had an outcome. asymmetric. \u0000Conclusion: Clinical characteristics of ptosis patients can determine the diagnosis and treatment that will be given to the patient.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"10 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79994285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Glaucoma is the second leading cause of blindness for over 70 million people worldwide. Bilateral blindness occurs with an estimated 10%. In Indonesia, the prevalence of glaucoma is 0,46%. That means that 4 to 5 out of 1.000 people suffer from glaucoma. Considering glaucoma as the second cause of blindness after cataracts in the world and its irreversible nature, this study was conducted to determine the characteristics of patients with primary glaucoma in the Glaucoma Clinic, Dr. Mohammad Hoesin General Hospital in 2021 based on age, gender, diagnosis, and intraocular pressure. Methods: This research is a descriptive retrospective study using secondary data through the medical record of patients in the Glaucoma Clinic, Dr. Mohammad Hoesin General Hospital Palembang from January to December 2021. The sample of this study was 20 people, and there were 40 eyes diagnosed with primary glaucoma. Results: The number of Primary Glaucoma patients was more in female patients, namely 11 patients (55,0%) with age varies at ≤ 50 years of age (45,0%), namely 51-60 patients (35,0%) and aged ≥ 61 years as many as 4 patients (25%), with an age range from 40 years to 70 years. Most patients were POAG (85%), with the highest eye pressure was 38,8mmHg, and 43,4 mmHg in PACG. Conclusion: There were 20 cases of primary glaucoma at the Glaucoma Clinic of Dr. Mohammad Hoesin General Hospital Palembang in 2021 with 40 affected eyes. Most patients were female, with most age group <50 years, and the most common type of glaucoma was open-angle.
简介:青光眼是全球超过7000万人失明的第二大原因。双侧失明的发生率约为10%。在印度尼西亚，青光眼的患病率为0.46%。这意味着每1000人中有4到5人患有青光眼。考虑到青光眼是世界上仅次于白内障的第二大致盲原因，且具有不可逆性，本研究根据年龄、性别、诊断和眼压，确定了2021年Mohammad Hoesin综合医院青光眼诊所原发性青光眼患者的特征。方法:本研究是一项描述性回顾性研究，使用二手数据，通过2021年1月至12月在Palembang Dr. Mohammad Hoesin总医院青光眼诊所的患者病历进行研究。这项研究的样本是20个人，其中有40只眼睛被诊断为原发性青光眼。结果:原发性青光眼患者以女性患者较多，为11例(55.0%)，年龄≤50岁(45.0%)，即51 ~ 60例(35.0%)，年龄≥61岁的患者多达4例(25%)，年龄范围为40 ~ 70岁。大多数患者为POAG (85%)， PACG患者眼压最高为38.8 mmHg, 44.3 mmHg。结论:2021年在巨港市穆罕默德·胡辛总医院青光眼门诊共收治原发性青光眼20例，患眼40只。患者以女性居多，年龄≥50岁者居多，开角型青光眼最为常见。
{"title":"Characteristics of Primary Glaucoma in Glaucoma Clinic of Dr. Mohammad Hoesin General Hospital, Palembang","authors":"Prima Maya Sari, Rizka Yunanda","doi":"10.37275/sjo.v5i2.75","DOIUrl":"https://doi.org/10.37275/sjo.v5i2.75","url":null,"abstract":"Introduction: Glaucoma is the second leading cause of blindness for over 70 million people worldwide. Bilateral blindness occurs with an estimated 10%. In Indonesia, the prevalence of glaucoma is 0,46%. That means that 4 to 5 out of 1.000 people suffer from glaucoma. Considering glaucoma as the second cause of blindness after cataracts in the world and its irreversible nature, this study was conducted to determine the characteristics of patients with primary glaucoma in the Glaucoma Clinic, Dr. Mohammad Hoesin General Hospital in 2021 based on age, gender, diagnosis, and intraocular pressure. \u0000Methods: This research is a descriptive retrospective study using secondary data through the medical record of patients in the Glaucoma Clinic, Dr. Mohammad Hoesin General Hospital Palembang from January to December 2021. The sample of this study was 20 people, and there were 40 eyes diagnosed with primary glaucoma. \u0000Results: The number of Primary Glaucoma patients was more in female patients, namely 11 patients (55,0%) with age varies at ≤ 50 years of age (45,0%), namely 51-60 patients (35,0%) and aged ≥ 61 years as many as 4 patients (25%), with an age range from 40 years to 70 years. Most patients were POAG (85%), with the highest eye pressure was 38,8mmHg, and 43,4 mmHg in PACG. \u0000Conclusion: There were 20 cases of primary glaucoma at the Glaucoma Clinic of Dr. Mohammad Hoesin General Hospital Palembang in 2021 with 40 affected eyes. Most patients were female, with most age group <50 years, and the most common type of glaucoma was open-angle.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85474632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Incidence rates of skin cancer have risen significantly over the last two decades. Most tumors develop in sun-exposed areas of the head and neck. Basal cell carcinoma (BCC) rarely metastasizes but can cause significant morbidity and death due to direct spread to the orbit, head, and neck and frequent recurrence. In addition, approximately 40% of BCC patients have other lesions after 5 years. Although there has been a lot of epidemiological data regarding the characteristics of BCC in developed countries, reports of BCC in Asia, especially in Southern Sumatra, are still at a minimum rate. Methods: This study retrospectively reviewed the medical records specific to periocular BCC. Data were collected from the patient register book recorded from January 2021 to May 2022. The clinical characteristics of patients with BCC, such as gender and age, clinicopathological findings of BCC lesions, and BCC management, were reviewed retrospectively. This study aims to determine the epidemiological profile of the malignant eyelid BCC patient, the BCC lesion characteristics, and the management of BCC cases at Mohammad Hoesin General Hospital Palembang. Results: From 16 BCC patients recruited for this study, most of them were 51–60 years old and 71–80 years old, each with 5 patients (31.3%). The female preponderance of 56.3%. Occulus dextra (56.3%), lower eyelid (62.5%), T1 (87.5%), nodular BCC (75,0%), and primary lesion (75,0%) were the most side, periocular site, size, histopathological subtype and recurrence, respectively. Most therapy done is excision (93,8%), while the leading reconstructive technique was Tenzel’s flap (50,0%). Conclusion: There is a slight preponderance of females as BCC patients. BCC is commonly found in elderly people. The lower eyelid and right side are the most frequent anatomical locations. Nodular is the most common histological subtype. In addition, lesions often present in T1 size and primary lesions. Lastly, the treatment is mainly surgical (excision), with Tenzel's flap as the most used reconstruction technique option.
{"title":"Characteristics of Malignant Eyelid Basal Cell Carcinoma in Dr. Mohammad Hoesin General Hospital: A Retrospective Study","authors":"Mutia Arnisa Putri, Ibrahim","doi":"10.37275/sjo.v5i2.73","DOIUrl":"https://doi.org/10.37275/sjo.v5i2.73","url":null,"abstract":"Introduction: Incidence rates of skin cancer have risen significantly over the last two decades. Most tumors develop in sun-exposed areas of the head and neck. Basal cell carcinoma (BCC) rarely metastasizes but can cause significant morbidity and death due to direct spread to the orbit, head, and neck and frequent recurrence. In addition, approximately 40% of BCC patients have other lesions after 5 years. Although there has been a lot of epidemiological data regarding the characteristics of BCC in developed countries, reports of BCC in Asia, especially in Southern Sumatra, are still at a minimum rate. \u0000Methods: This study retrospectively reviewed the medical records specific to periocular BCC. Data were collected from the patient register book recorded from January 2021 to May 2022. The clinical characteristics of patients with BCC, such as gender and age, clinicopathological findings of BCC lesions, and BCC management, were reviewed retrospectively. This study aims to determine the epidemiological profile of the malignant eyelid BCC patient, the BCC lesion characteristics, and the management of BCC cases at Mohammad Hoesin General Hospital Palembang. \u0000Results: From 16 BCC patients recruited for this study, most of them were 51–60 years old and 71–80 years old, each with 5 patients (31.3%). The female preponderance of 56.3%. Occulus dextra (56.3%), lower eyelid (62.5%), T1 (87.5%), nodular BCC (75,0%), and primary lesion (75,0%) were the most side, periocular site, size, histopathological subtype and recurrence, respectively. Most therapy done is excision (93,8%), while the leading reconstructive technique was Tenzel’s flap (50,0%). \u0000Conclusion: There is a slight preponderance of females as BCC patients. BCC is commonly found in elderly people. The lower eyelid and right side are the most frequent anatomical locations. Nodular is the most common histological subtype. In addition, lesions often present in T1 size and primary lesions. Lastly, the treatment is mainly surgical (excision), with Tenzel's flap as the most used reconstruction technique option.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81175551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Microbial agents cause infectious processes, which may result in corneal inflammation leading to corneal necrosis, ulceration, and perforation. This disorder is one of the major etiologies of monocular blindness in developing countries in Asia, Africa, and the Middle East. The etiology of corneal ulcers varies in different regions. Methods: This research is a descriptive study approach. Data obtained from the medical records of patients who were registered as corneal ulcer patients in Dr. Mohammad Hoesin Palembang from July 2021 to September 2021. Results: A total of 9 patients were diagnosed with a corneal ulcer. The number of corneal ulcer patients was more in male patients (77.8%). The age of patients varies from 16 years to 63 years, and most elderly patients are diagnosed with this condition. Predisposing factors are unknown in most patients. The most common location for ulcers is the central cornea (88.9%), with >6 mm in size. Hypopyon is found in 2 patients (22.2%), while perforation and corneal melting in 1 patient consecutively. The most common microbiological profiles of corneal ulcer patients in this study are unspecified (66.7%), while ulcers due to bacteria in the second place of the microbiological profile (33.3%) consist of Enterobacter aerogenes, Staphylococcus epidermidis, and Pantoea spp and sensitive to almost all kinds of antibiotics. Conclusion: The most common microbiological profiles of corneal ulcer patients in this study are unspecified, while ulcer due to bacteria in the second place of the microbiological profile consists of Enterobacter aerogenes, Staphylococcus epidermidis, and Pantoea spp and sensitive to almost all kinds of antibiotics.
{"title":"Microbiological Profile of Corneal Ulcer in Dr. Mohammad Hoesin General Hospital Palembang, Indonesia: July to September 2021","authors":"Rezandi Aziztama, Anang Tribowo","doi":"10.37275/sjo.v5i2.74","DOIUrl":"https://doi.org/10.37275/sjo.v5i2.74","url":null,"abstract":"Introduction: Microbial agents cause infectious processes, which may result in corneal inflammation leading to corneal necrosis, ulceration, and perforation. This disorder is one of the major etiologies of monocular blindness in developing countries in Asia, Africa, and the Middle East. The etiology of corneal ulcers varies in different regions. \u0000Methods: This research is a descriptive study approach. Data obtained from the medical records of patients who were registered as corneal ulcer patients in Dr. Mohammad Hoesin Palembang from July 2021 to September 2021. \u0000Results: A total of 9 patients were diagnosed with a corneal ulcer. The number of corneal ulcer patients was more in male patients (77.8%). The age of patients varies from 16 years to 63 years, and most elderly patients are diagnosed with this condition. Predisposing factors are unknown in most patients. The most common location for ulcers is the central cornea (88.9%), with >6 mm in size. Hypopyon is found in 2 patients (22.2%), while perforation and corneal melting in 1 patient consecutively. The most common microbiological profiles of corneal ulcer patients in this study are unspecified (66.7%), while ulcers due to bacteria in the second place of the microbiological profile (33.3%) consist of Enterobacter aerogenes, Staphylococcus epidermidis, and Pantoea spp and sensitive to almost all kinds of antibiotics. \u0000Conclusion: The most common microbiological profiles of corneal ulcer patients in this study are unspecified, while ulcer due to bacteria in the second place of the microbiological profile consists of Enterobacter aerogenes, Staphylococcus epidermidis, and Pantoea spp and sensitive to almost all kinds of antibiotics.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85100636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Visual acuity is the ability of the eye to see an object clearly, and this depends on the ability of the eye to accommodate. Myopia is one of the causes of a sharp decline in vision in children aged 8-12 years. Close working distance is one of the most frequently mentioned risk factors for myopia. Head and back posture that bends forward when reading or doing other close-up tasks causes a higher prevalence of myopia. This study was conducted to describe risk factors related to decreased vision in elementary school children. Methods. The study was a descriptive research with a sample of 100 elementary school children taken by simple random sampling. Data was taken using a questionnaire and a Snellen chart. Results. A total of 100 students participated in this study. Most of the participants were aged 11 years old. Based on visual acuity, 20 students have decreased right eye vision, and 21% have decreased left eye vision. Most respondents read every day for 1 hour time as many as 58 (58%) people and had screen time for less than 2 hours (52%). In addition, based on family history, most respondents had parents' glasses (73%). Conclusion. More elementary school children had normal right and left eye vision than those with decreased vision. Most respondents have less screen time and less reading duration.
{"title":"Risk Factors Related to Decreased Vision in Primary School Children in Palembang","authors":"Dicky Hartono","doi":"10.37275/sjo.v5i1.66","DOIUrl":"https://doi.org/10.37275/sjo.v5i1.66","url":null,"abstract":"Introduction. Visual acuity is the ability of the eye to see an object clearly, and this depends on the ability of the eye to accommodate. Myopia is one of the causes of a sharp decline in vision in children aged 8-12 years. Close working distance is one of the most frequently mentioned risk factors for myopia. Head and back posture that bends forward when reading or doing other close-up tasks causes a higher prevalence of myopia. This study was conducted to describe risk factors related to decreased vision in elementary school children. \u0000Methods. The study was a descriptive research with a sample of 100 elementary school children taken by simple random sampling. Data was taken using a questionnaire and a Snellen chart. \u0000Results. A total of 100 students participated in this study. Most of the participants were aged 11 years old. Based on visual acuity, 20 students have decreased right eye vision, and 21% have decreased left eye vision. Most respondents read every day for 1 hour time as many as 58 (58%) people and had screen time for less than 2 hours (52%). In addition, based on family history, most respondents had parents' glasses (73%). \u0000Conclusion. More elementary school children had normal right and left eye vision than those with decreased vision. Most respondents have less screen time and less reading duration.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74268054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photodynamic therapy (PDT) is a therapy that uses drugs, called photosensitizers or photosensitizing agents, and a specific type of light. When photosensitizers are exposed to certain wavelengths of light, they produce oxygen that kills nearby cells. PDT is achieved by a photodynamic reaction induced by the excitation of a photosensitizer exposed to light. In the field of ophthalmology, PDT was approved for the first time about ten years ago for cases of age-related macular degeneration (AMD). Neovascular age-related macular degeneration (AMD) is a vision-threatening disease characterized by pathological macular neovascularization. After that, PDT was approved for use in choroidal neovascularization (CNV) cases in pathological myopia.3 This literature review aims to describe the history of PDT use and the basic principles of photodynamic therapy in ophthalmology.
{"title":"History and Basic Principles of Photodynamic Therapy Use in Ophthalmology","authors":"Abdul Karim Ansyori","doi":"10.37275/sjo.v5i1.62","DOIUrl":"https://doi.org/10.37275/sjo.v5i1.62","url":null,"abstract":"Photodynamic therapy (PDT) is a therapy that uses drugs, called photosensitizers or photosensitizing agents, and a specific type of light. When photosensitizers are exposed to certain wavelengths of light, they produce oxygen that kills nearby cells. PDT is achieved by a photodynamic reaction induced by the excitation of a photosensitizer exposed to light. In the field of ophthalmology, PDT was approved for the first time about ten years ago for cases of age-related macular degeneration (AMD). Neovascular age-related macular degeneration (AMD) is a vision-threatening disease characterized by pathological macular neovascularization. After that, PDT was approved for use in choroidal neovascularization (CNV) cases in pathological myopia.3 This literature review aims to describe the history of PDT use and the basic principles of photodynamic therapy in ophthalmology.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86371278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Depression is a chronic and often recurrent psychiatric disorder among older people, and its association with cataracts has not been well defined. Several studies have shown that depression is a prevalent mental health problem in ophthalmological practice and is often unrecognized or untreated. A systematic review was conducted to investigate the prevalence of depression in patients with visual impairment in cataracts.Methods. A literature search was performed on PubMed and Medline in the last 10 years (2011 to 2021). The search strategy used the following terms: (prevalence) and (visual impairment or blindness) and (cataract) and (depression or depressive symptoms). Of the 544 electronics, 226 articles were selected in free full text and 10 studies were identified as being possibly relevant. Results. Depression was associated with visual impairment in all studies. The prevalence of depression is higher in patients with eye disease.Conclusion. The prevalence of depression among eye disease patients was higher than that in healthy people. Cataract surgery is associated with an improvement in depressive symptomatology. More research is needed to identify effective strategies for the prevention and management of depression in patients with cataracts or visual impairment.
{"title":"Prevalence of Depression in Patients with Visual Impairment in Cataract: A Systematic Literature Review","authors":"Freshcilia Oktaviyani","doi":"10.37275/sjo.v5i1.63","DOIUrl":"https://doi.org/10.37275/sjo.v5i1.63","url":null,"abstract":"Introduction. Depression is a chronic and often recurrent psychiatric disorder among older people, and its association with cataracts has not been well defined. Several studies have shown that depression is a prevalent mental health problem in ophthalmological practice and is often unrecognized or untreated. A systematic review was conducted to investigate the prevalence of depression in patients with visual impairment in cataracts.Methods. A literature search was performed on PubMed and Medline in the last 10 years (2011 to 2021). The search strategy used the following terms: (prevalence) and (visual impairment or blindness) and (cataract) and (depression or depressive symptoms). Of the 544 electronics, 226 articles were selected in free full text and 10 studies were identified as being possibly relevant. Results. Depression was associated with visual impairment in all studies. The prevalence of depression is higher in patients with eye disease.Conclusion. The prevalence of depression among eye disease patients was higher than that in healthy people. Cataract surgery is associated with an improvement in depressive symptomatology. More research is needed to identify effective strategies for the prevention and management of depression in patients with cataracts or visual impairment.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86219703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Retinoblastoma is a cancer that arises because both copies of the RB1 gene that normally suppresses retinoblastoma are lost from a developing retinal cell in fetuses, babies, and young children. Retinoblastoma is the prototype genetic cancer in one or both eyes of young children, most retinoblastomas are initiated by biallelic mutation of the retinoblastoma tumor suppressor gene, RB1, in a developing retinal cell. All those with bilateral retinoblastoma have heritable cancer, although 95% have not inherited the RB1 mutation. Nonheritable retinoblastoma is always unilateral, with 98% caused by loss of both RB1 alleles from the tumor, whereas 2% have normal RB1 in tumors initiated by amplification of the MYCN oncogene. A rare subset of retinoblastoma is initiated by somatic amplification of the MYCN oncogene in a predisposing retinal cell. The retinoblastoma protein (pRB), encoded by RB1, is an important transcription factor.
{"title":"Molecular Genetics Mutations of Retinoblastoma","authors":"Mutia Arnisa Putri","doi":"10.37275/sjo.v4i2.50","DOIUrl":"https://doi.org/10.37275/sjo.v4i2.50","url":null,"abstract":"Retinoblastoma is a cancer that arises because both copies of the RB1 gene that normally suppresses retinoblastoma are lost from a developing retinal cell in fetuses, babies, and young children. Retinoblastoma is the prototype genetic cancer in one or both eyes of young children, most retinoblastomas are initiated by biallelic mutation of the retinoblastoma tumor suppressor gene, RB1, in a developing retinal cell. All those with bilateral retinoblastoma have heritable cancer, although 95% have not inherited the RB1 mutation. Nonheritable retinoblastoma is always unilateral, with 98% caused by loss of both RB1 alleles from the tumor, whereas 2% have normal RB1 in tumors initiated by amplification of the MYCN oncogene. A rare subset of retinoblastoma is initiated by somatic amplification of the MYCN oncogene in a predisposing retinal cell. The retinoblastoma protein (pRB), encoded by RB1, is an important transcription factor.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81613328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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