Introduction. Ocular myasthenia gravis (OMG) is an autoimmune disease which is characterized by weakness of extraocular muscles, levator palpebrae and orbicularis oculi, resulting in ptosis and binocular diplopia. Nearly all patients present with eyelid and extra ocular muscles involvement. Approximately 30% to 80% of patients with OMG experience a conversion to generalized myasthenia gravis (GMG) within 2 years. There are not only have ptosis and diplopia but also limb weakness,bulbar symptoms, or even respiratory failure. Objective. To observe the clinical features of OMG to GMG and risk factors and median time to conversion of OMG to GMG of myasthenia gravis patients in Mohammad Hoesin General Hospital Palembang. Method. This study is a cohort retrospective study and the data were collected from the medical records of 91 patients who were registered as myasthenia gravis patients during September 2018 to March 2020. Sosiodemographic and clinical characteristics, including onset of OMG to GMG, history of smoking, presence of thymic abnormalities, and medications received were reviewed retrospectively. Result. A total of 91 OMG patients were observed in this study with 32 (35,2%) patients converted from ocular myastenia gravis to general myastenia gravis. Median conversion time to GMG was 34 months. Risk factor for convertion cases of OMG to MGG was receiving immunosupressive agents(Risk: 14.7, 95% CI 4.83, 44.7), thymus hyperplasia (Risk: 3.36, CI 95% 0.33, 33.6), Female (Risk: 2.41, 95% CI 0.94, 6.17), Smoking (Risk: 1.56, 95% CI 0.31, 7.81). Conclusion. Ptosis was the definitive sign for OMG in this study, with all patients had ptosis, thus it needs the colaboration from neuroophthalmologist and neurologist to diagnose and manage this case. Most of converted case was female and those who receive an immunosupressive agent therapy.
介绍。眼部重症肌无力是一种以眼外肌、提睑肌和眼轮匝肌无力为特征的自身免疫性疾病，可导致眼睑下垂和双眼复视。几乎所有的患者都有眼睑和眼外肌受累。大约30%至80%的OMG患者在2年内转变为全身性重症肌无力(GMG)。不仅有上睑下垂、复视，还有肢体无力、球症状，甚至呼吸衰竭。目标。目的:观察巨港默罕默德·胡辛总医院重症肌无力患者OMG转GMG的临床特点、OMG转GMG的危险因素及中位时间。方法。本研究是一项队列回顾性研究，数据收集自2018年9月至2020年3月期间登记为重症肌无力患者的91例患者的病历。回顾性回顾了患者的生理人口学和临床特征，包括OMG到GMG的发病、吸烟史、胸腺异常的存在和接受的药物治疗。结果。本研究共观察了91例OMG患者，其中32例(35.2%)患者由眼型重症肌无力转化为全身性重症肌无力。转为GMG的中位时间为34个月。OMG转化为MGG病例的危险因素是接受免疫抑制剂(风险:14.7,95% CI 4.83, 44.7)、胸腺增生(风险:3.36,95% CI 0.33, 33.6)、女性(风险:2.41,95% CI 0.94, 6.17)、吸烟(风险:1.56,95% CI 0.31, 7.81)。结论。本研究中，上睑下垂是OMG的明确征象，所有患者均有上睑下垂，需要神经眼科医生和神经科医生共同诊断和处理。大多数转化病例为女性和接受免疫抑制剂治疗的患者。
{"title":"Factors Affecting Generalization of Ocular Myasthenia Gravis in Palembang","authors":"Z. Farid, D. Wahyuni","doi":"10.37275/SJO.V3I2.55","DOIUrl":"https://doi.org/10.37275/SJO.V3I2.55","url":null,"abstract":"Introduction. Ocular myasthenia gravis (OMG) is an autoimmune disease which is characterized by weakness of extraocular muscles, levator palpebrae and orbicularis oculi, resulting in ptosis and binocular diplopia. Nearly all patients present with eyelid and extra ocular muscles involvement. Approximately 30% to 80% of patients with OMG experience a conversion to generalized myasthenia gravis (GMG) within 2 years. There are not only have ptosis and diplopia but also limb weakness,bulbar symptoms, or even respiratory failure. \u0000Objective. To observe the clinical features of OMG to GMG and risk factors and median time to conversion of OMG to GMG of myasthenia gravis patients in Mohammad Hoesin General Hospital Palembang. \u0000Method. This study is a cohort retrospective study and the data were collected from the medical records of 91 patients who were registered as myasthenia gravis patients during September 2018 to March 2020. Sosiodemographic and clinical characteristics, including onset of OMG to GMG, history of smoking, presence of thymic abnormalities, and medications received were reviewed retrospectively. \u0000Result. A total of 91 OMG patients were observed in this study with 32 (35,2%) patients converted from ocular myastenia gravis to general myastenia gravis. Median conversion time to GMG was 34 months. Risk factor for convertion cases of OMG to MGG was receiving immunosupressive agents(Risk: 14.7, 95% CI 4.83, 44.7), thymus hyperplasia (Risk: 3.36, CI 95% 0.33, 33.6), Female (Risk: 2.41, 95% CI 0.94, 6.17), Smoking (Risk: 1.56, 95% CI 0.31, 7.81). \u0000Conclusion. Ptosis was the definitive sign for OMG in this study, with all patients had ptosis, thus it needs the colaboration from neuroophthalmologist and neurologist to diagnose and manage this case. Most of converted case was female and those who receive an immunosupressive agent therapy.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89784154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Diagnosis of vitreous bleeding is generally straightforward and it can be made through history, ophthalmological examination and fundoscopy. However, the management is determined by the underlying etiology. The most common causes as factors that cause opposite vitreous bleeding include retinopathy of proliferative diabetes, posterior vitreous detachment (PVD) and trauma in 59-88.5% of cases. Reported a case of vitreous hemorrhage due to closed eyeball trauma performed by pars plana vitrectomy and endolaser with significant vision improvement. Case Presentation. A male, 21 years old, student, lived in suburban, came to the Polyclinic of RSMH on July 2019. Approximately 1 month ago the patient complained that his right eye vision suddenly felt blurry after being hit by volleyball from the front from a distance of 1 meter while playing volleyball with his friends. Patients complain of the view of the right eye as if it were covered with a red shadow accompanied by pain around the right eye. Ophthalmological examination obtained vision of this patient is a wave of the hand that is 1/300 in the right eye and 6/6 in the left eye that shows the disorder is unilateral with a fairly poor decrease in vision. During intraoperative right eye hemorrhage was found to nearly cover the retina with the source of bleeding in peripheral retinal blood vessels which when found intraoperatively were not found extravasation or active bleeding. Conclusion. The operative action of pars plana vitrectomy gives a clinically significant result that is obtained very good sharp eyesight and from the examination results obtained echofree on vitreous. Proper timing is very important in determining the management of vitreous bleeding in order to get good results and minimize the risk of complications that can occur.
{"title":"Diagnosis and Management of Bleeding Vitreous by Trauma Closed Eyeball","authors":"Rika Anggraini, Ak Ansyori, Ramzi Amin","doi":"10.37275/sjo.v2i2.14","DOIUrl":"https://doi.org/10.37275/sjo.v2i2.14","url":null,"abstract":"Introduction. Diagnosis of vitreous bleeding is generally straightforward and it can be made through history, ophthalmological examination and fundoscopy. However, the management is determined by the underlying etiology. The most common causes as factors that cause opposite vitreous bleeding include retinopathy of proliferative diabetes, posterior vitreous detachment (PVD) and trauma in 59-88.5% of cases. Reported a case of vitreous hemorrhage due to closed eyeball trauma performed by pars plana vitrectomy and endolaser with significant vision improvement. \u0000Case Presentation. A male, 21 years old, student, lived in suburban, came to the Polyclinic of RSMH on July 2019. Approximately 1 month ago the patient complained that his right eye vision suddenly felt blurry after being hit by volleyball from the front from a distance of 1 meter while playing volleyball with his friends. Patients complain of the view of the right eye as if it were covered with a red shadow accompanied by pain around the right eye. Ophthalmological examination obtained vision of this patient is a wave of the hand that is 1/300 in the right eye and 6/6 in the left eye that shows the disorder is unilateral with a fairly poor decrease in vision. During intraoperative right eye hemorrhage was found to nearly cover the retina with the source of bleeding in peripheral retinal blood vessels which when found intraoperatively were not found extravasation or active bleeding. \u0000Conclusion. The operative action of pars plana vitrectomy gives a clinically significant result that is obtained very good sharp eyesight and from the examination results obtained echofree on vitreous. Proper timing is very important in determining the management of vitreous bleeding in order to get good results and minimize the risk of complications that can occur.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73337162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Background: Phacoemulsification is a technique of modern cataract surgery with smaller corneal incision than conventional techniques but uses various effects on springs that cause dry eye syndrome (DES). DES is a multifactorial defect of tears and ocular surfaces characterized by eye discomfort. Examination of DES can be done by examining Schirmer 1 and Tear Break Up Time (TBUT). Purpose: To determine the accuracy, sensitivity and specificity of the Schirmer test dan TBUT in postoperative patients with phacoemulsification techniques at the Rumah Sakit Khusus Mata Province of South Sumatra. Method: Diagnostic test has been done in order to the accuracy, sensitivity and specificity of the Schirmer test dan TBUT on DES in post operative cataract surgery with phacoemulsification techniques. This study has been conduct Schirmer 1 test and TBUT was done periodically from 1 week, 2 weeks and 1 month after cataract surgery. The data analysis has been done with diagnostic research by SPSS version 20.0 (SPSS, Inc Chicago, Illinois). Result: 40 study samples of post operative cataract surgery with phacoemulsification technique obtained by female sex with 22 out of samples were (55%), with an average age of patients between of 60-70 years.The accuracy of Shirmer 1 and TBUT test was 0,425 and the sensitivity value was 39.5% and also the specificity value was 100%. Conclusion: Schirmer 1 test and TBUT in patients of post cataract surgery with phacoemulsification techniques are specific (100%) but less sensitive (39,5%)
背景:超声乳化术是一种现代白内障手术技术，其角膜切口比传统技术小，但对引起干眼综合征(DES)的弹簧有不同的影响。DES是一种多因素的泪液和眼表缺陷，以眼睛不适为特征。DES的检查可以通过检查Schirmer 1和撕裂破裂时间(TBUT)来完成。目的:探讨南苏门答腊省Rumah Sakit Khusus Mata省超声乳化术后患者Schirmer试验和TBUT的准确性、敏感性和特异性。方法:采用超声乳化术对白内障术后DES进行Schirmer试验和TBUT诊断的准确性、敏感性和特异性。本研究进行了Schirmer 1试验，并在白内障手术后1周、2周和1个月定期进行TBUT。数据分析已完成与诊断研究SPSS 20.0版(SPSS, Inc芝加哥，伊利诺伊州)。结果:40例白内障术后超声乳化技术研究样本为女性，其中22例(55%)，患者平均年龄在60-70岁之间。Shirmer 1和TBUT检测的准确率为0.425，灵敏度为39.5%，特异度为100%。结论:超声乳化白内障术后患者的Schirmer - 1试验和TBUT具有特异性(100%)，但敏感性较低(39.5%)。
{"title":"Comparison of Schirmer and Tear Break Up Time (TBUT) Diagnostic Test of Dry Eye Following Phacoemulsification Cataract Surgery","authors":"Disty Andryani, Petty Purwanita, Anang Tribowo","doi":"10.37275/sjo.v2i1.41","DOIUrl":"https://doi.org/10.37275/sjo.v2i1.41","url":null,"abstract":"Abstract \u0000Background: Phacoemulsification is a technique of modern cataract surgery with smaller corneal incision than conventional techniques but uses various effects on springs that cause dry eye syndrome (DES). DES is a multifactorial defect of tears and ocular surfaces characterized by eye discomfort. Examination of DES can be done by examining Schirmer 1 and Tear Break Up Time (TBUT). \u0000Purpose: To determine the accuracy, sensitivity and specificity of the Schirmer test dan TBUT in postoperative patients with phacoemulsification techniques at the Rumah Sakit Khusus Mata Province of South Sumatra. \u0000Method: Diagnostic test has been done in order to the accuracy, sensitivity and specificity of the Schirmer test dan TBUT on DES in post operative cataract surgery with phacoemulsification techniques. This study has been conduct Schirmer 1 test and TBUT was done periodically from 1 week, 2 weeks and 1 month after cataract surgery. The data analysis has been done with diagnostic research by SPSS version 20.0 (SPSS, Inc Chicago, Illinois). \u0000Result: 40 study samples of post operative cataract surgery with phacoemulsification technique obtained by female sex with 22 out of samples were (55%), with an average age of patients between of 60-70 years.The accuracy of Shirmer 1 and TBUT test was 0,425 and the sensitivity value was 39.5% and also the specificity value was 100%. \u0000Conclusion: Schirmer 1 test and TBUT in patients of post cataract surgery with phacoemulsification techniques are specific (100%) but less sensitive (39,5%)","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79373345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Retinal Vein Occlusion (RVO) is the second most common retinal blood vessel disease after diabetic retinopathy. CRVO is an acute blockage of the central retinal vein that causes abnormalities in the retina, characterized by sudden decreased vision. Based on the potential for vision loss from this retinal disease, proper diagnosis and management is needed to prevent further complications. Case Presentation. A man, age 50 years old, a civil servant, came to the eye clinic of Mohammad Hosein Hospital on February 2017. The main complaint was vision of right eye suddenly blurred since 5 months before. Based on the above examination found decreased vision in one eye, with visual acuity better than 6/60 and no RAPD. The funduscopic examination above shows the presence of dilatation and tortousity in the central retinal vein, dot / blot bleeding and flame shaped hemorrhages in all quadrants, exudates, neovascularization of the retina and optic disk, and the presence of edema in the optic disc and macula. Conclusion. Management performed on these patients is by performing a Pan-Retinal Photocoagulation (PRP) laser and Grid-Pattern Photocoagulation. The selection of this therapy is based on the consideration that the patient has been suffering from CRVO for more than 3 months.
{"title":"Laser Pan-Retinal Photocoagulation to Treat Central Retinal Vein Occlusion","authors":"Roland Iqbal, Ak Ansyori, Ramzi Amin","doi":"10.37275/sjo.v2i2.13","DOIUrl":"https://doi.org/10.37275/sjo.v2i2.13","url":null,"abstract":"Introduction. Retinal Vein Occlusion (RVO) is the second most common retinal blood vessel disease after diabetic retinopathy. CRVO is an acute blockage of the central retinal vein that causes abnormalities in the retina, characterized by sudden decreased vision. Based on the potential for vision loss from this retinal disease, proper diagnosis and management is needed to prevent further complications. \u0000Case Presentation. A man, age 50 years old, a civil servant, came to the eye clinic of Mohammad Hosein Hospital on February 2017. The main complaint was vision of right eye suddenly blurred since 5 months before. Based on the above examination found decreased vision in one eye, with visual acuity better than 6/60 and no RAPD. The funduscopic examination above shows the presence of dilatation and tortousity in the central retinal vein, dot / blot bleeding and flame shaped hemorrhages in all quadrants, exudates, neovascularization of the retina and optic disk, and the presence of edema in the optic disc and macula. \u0000Conclusion. Management performed on these patients is by performing a Pan-Retinal Photocoagulation (PRP) laser and Grid-Pattern Photocoagulation. The selection of this therapy is based on the consideration that the patient has been suffering from CRVO for more than 3 months.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83862346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Macular hole is a defect in the retina involving the macula and fovea, in the form of damage to full thickness from the internal limiting membrane (ILM) to the outermost part of the photoreceptor layer . It was more often found in women. In patients with myopia disorders can be found at a younger age. In this case we report the macular hole caused by blunt trauma, as was the first time a macular hole case was discovered. Case Presentation. A man 24-year-old, Mr. C, came to Palembang RSMH eye clinic on August 15, 2014 with complaints of blurred right eye vision. Main Complaints: Right eye blurred. History Disease: Right eye blurred for about 3 months before entering the hospital. Blur is felt after the patient had a motorcycle accident 3 months ago. At that time the collision sufferer avoided the truck, the right eye hit the motorcycle handlebar, the patient then fell from the motorcycle and hit the highway head. A history of frequent headaches is denied, nausea, vomiting is denied, history of seeing in tunnels is denied. Supporting examination is Amsler Grid Oculi Dextra: there is a black hole in the middle of the image. differential diagnosis is Traumatic Macular Hole OD, Lamellar Macular Hole OD, work diagnosis is Traumatic Macular Hole stage 3 OD. Conclusion. Traumatic macular holes can occur immediately after blunt trauma to the eyeball, the accuracy of the diagnosis and the speed of the timing for surgery, greatly determining the prognosis. Vitrectomy and combined with internal limiting membrane peeling have been shown to provide excellent results in macular surgery in macular hole cases.
{"title":"Diagnosis and Management of Macular Holes Traumatic","authors":"Reny Violeta, Ak Ansyori, Ramzi Amin","doi":"10.37275/sjo.v2i1.15","DOIUrl":"https://doi.org/10.37275/sjo.v2i1.15","url":null,"abstract":"Introduction. Macular hole is a defect in the retina involving the macula and fovea, in the form of damage to full thickness from the internal limiting membrane (ILM) to the outermost part of the photoreceptor layer . It was more often found in women. In patients with myopia disorders can be found at a younger age. In this case we report the macular hole caused by blunt trauma, as was the first time a macular hole case was discovered. \u0000Case Presentation. A man 24-year-old, Mr. C, came to Palembang RSMH eye clinic on August 15, 2014 with complaints of blurred right eye vision. Main Complaints: Right eye blurred. History Disease: Right eye blurred for about 3 months before entering the hospital. Blur is felt after the patient had a motorcycle accident 3 months ago. At that time the collision sufferer avoided the truck, the right eye hit the motorcycle handlebar, the patient then fell from the motorcycle and hit the highway head. A history of frequent headaches is denied, nausea, vomiting is denied, history of seeing in tunnels is denied. Supporting examination is Amsler Grid Oculi Dextra: there is a black hole in the middle of the image. differential diagnosis is Traumatic Macular Hole OD, Lamellar Macular Hole OD, work diagnosis is Traumatic Macular Hole stage 3 OD. \u0000Conclusion. Traumatic macular holes can occur immediately after blunt trauma to the eyeball, the accuracy of the diagnosis and the speed of the timing for surgery, greatly determining the prognosis. Vitrectomy and combined with internal limiting membrane peeling have been shown to provide excellent results in macular surgery in macular hole cases.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80630383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Background: Diabetes mellitus (DM) have a direct effect to retinal neural tissue. Diabetic retinopathy slowly proggress with reserved visual acuity and no symptoms in early stage. Retinal nerve fiber layer thickness significantly decrease in type 2 diabetes mellitus patients related to glycemic blood level. Purpose: To analyze the relationship between HbA1c level and retinal nerve fiber layer thickness in diabetic retinopathy patients. Methods: A cross sectional analytical study was conducted in RSUP dr. Mohammad Hoesin Palembang from October 2017 until March 2018. Sixty eight type 2 diabetes mellitus patients consist of various grade of diabetic retinopathy. Measurement of HbA1c level was performed on these samples and retinal nerve fiber layer thickness was measured by Optical Coherence Tomography (OCT). Results: There is a significant relationship between duration of DM with RNFL thickness (p = 0,002). There is a significant relationship between hypertension with RNFL thickness (p = 0,007). There is a significant relationship between HbA1c level with RNFL thickness in all quadrants (superior, nasal, inferior quadrants p = 0,000, temporal quadrant p = 0,011). The most important factor of RNFL thinning in superior, nasal and inferior quadrants is HbA1c level (superior and nasal adjusted p value 0,002, inferior adjusted p value 0,002) while in temporal quadrant is hypertension (adjusted p value 0,042). Conclusion: There is a significant relationship between HbA1c level with RNFL thickness in all quadrants in which the patients with HbA1c > 7% have a higher risk of thinner RNFL compared to patients with HbA1c ≤ 7%.
{"title":"Relationship Between HbA1c Level with Retinal Nerve Fiber Layer Thickness in Diabetic Retinopathy","authors":"Febrina Art, Ak Ansyori, Ramzi Amin","doi":"10.37275/sjo.v2i2.34","DOIUrl":"https://doi.org/10.37275/sjo.v2i2.34","url":null,"abstract":"Abstract \u0000Background: Diabetes mellitus (DM) have a direct effect to retinal neural tissue. Diabetic retinopathy slowly proggress with reserved visual acuity and no symptoms in early stage. Retinal nerve fiber layer thickness significantly decrease in type 2 diabetes mellitus patients related to glycemic blood level. \u0000Purpose: To analyze the relationship between HbA1c level and retinal nerve fiber layer thickness in diabetic retinopathy patients. \u0000Methods: A cross sectional analytical study was conducted in RSUP dr. Mohammad Hoesin Palembang from October 2017 until March 2018. Sixty eight type 2 diabetes mellitus patients consist of various grade of diabetic retinopathy. Measurement of HbA1c level was performed on these samples and retinal nerve fiber layer thickness was measured by Optical Coherence Tomography (OCT). \u0000Results: There is a significant relationship between duration of DM with RNFL thickness (p = 0,002). There is a significant relationship between hypertension with RNFL thickness (p = 0,007). There is a significant relationship between HbA1c level with RNFL thickness in all quadrants (superior, nasal, inferior quadrants p \u0000= 0,000, temporal quadrant p = 0,011). The most important factor of RNFL thinning in superior, nasal and inferior quadrants is HbA1c level (superior and nasal adjusted p value 0,002, inferior adjusted p value 0,002) while in temporal quadrant is hypertension (adjusted p value 0,042). \u0000Conclusion: There is a significant relationship between HbA1c level with RNFL thickness in all quadrants in which the patients with HbA1c > 7% have a higher risk of thinner RNFL compared to patients with HbA1c ≤ 7%.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73585649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roland Iqbal, Prima Maya Sari, Ramzi Amin, Fidalia
ABSTRACT Introduction and Objectives: Diabetes mellitus (DM) is known to have a biomechanical effect on tissue. High blood glucose concentrations that lead to increased production of free radical intermediates causes ocular rigidity (OR) changes. This change can effect intraocular pressure (IOP) in patients with type 2 DM. This study to determine correlation between ocular rigidity with IOP in patients with type 2 DM. Methods: A cross-sectional study with a correlation test design of OR with IOP in type 2 DM patients was conducted in RSUP dr. Mohammad Hoesin Palembang from January until June 2018. Eighty eye samples consist of 60 type 2 DM and 20 control group. IOP examination was performed using a Goldmann applanation tonometer and OR measurements using schiotz tonometer with two loads then assessed in Friedenwald differential tables. Result: There was a significant correlation between diabetic retinopathy and OR (p=0,000). There was a significant correlation between OR and IOP in NPDR and PDR group (p=0,000). There was a significant relationship between patient age with OR and IOP (p<0,05). Conclusion: There is a significant correlation between ocular rigidity and IOP in people with type 2 DM.
摘要简介和目的:糖尿病(DM)已知对组织有生物力学影响。高血糖浓度导致自由基中间体产生增加，引起眼强直(OR)变化。这种变化会影响2型糖尿病患者的眼内压(IOP)。本研究旨在确定2型糖尿病患者眼刚性与IOP之间的相关性。方法:2018年1月至6月，RSUP Mohammad Hoesin Palembang博士在2型糖尿病患者中进行了一项横断研究，并进行了OR与IOP的相关试验设计。2型糖尿病60例，对照组20例。使用Goldmann压平眼压仪进行IOP检查，使用两种负荷的schiotz眼压仪进行OR测量，然后在Friedenwald微分表中进行评估。结果:糖尿病视网膜病变与OR有显著相关性(p= 0000)。NPDR组和PDR组OR与IOP有显著相关性(p= 0000)。患者年龄与IOP有显著相关性(p< 0.05)。结论:2型糖尿病患者眼强直与IOP有显著相关性。
{"title":"Correlation Between Ocular Rigidity With Intraocular Pressure In Patient With Type 2 Diabetes Mellitus","authors":"Roland Iqbal, Prima Maya Sari, Ramzi Amin, Fidalia","doi":"10.37275/sjo.v2i1.38","DOIUrl":"https://doi.org/10.37275/sjo.v2i1.38","url":null,"abstract":"ABSTRACT \u0000Introduction and Objectives: Diabetes mellitus (DM) is known to have a biomechanical effect on tissue. High blood glucose concentrations that lead to increased production of free radical intermediates causes ocular rigidity (OR) changes. This change can effect intraocular pressure (IOP) in patients with type 2 DM. This study to determine correlation between ocular rigidity with IOP in patients with type 2 DM. \u0000Methods: A cross-sectional study with a correlation test design of OR with IOP in type 2 DM patients was conducted in RSUP dr. Mohammad Hoesin Palembang from January until June 2018. Eighty eye samples consist of 60 type 2 DM and 20 control group. IOP examination was performed using a Goldmann applanation tonometer and OR measurements using schiotz tonometer with two loads then assessed in Friedenwald differential tables. \u0000Result: There was a significant correlation between diabetic retinopathy and OR (p=0,000). There was a significant correlation between OR and IOP in NPDR and PDR group (p=0,000). There was a significant relationship between patient age with OR and IOP (p<0,05). \u0000Conclusion: There is a significant correlation between ocular rigidity and IOP in people with type 2 DM.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"283 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77871803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Submacular hemorrhage is defined as the presence of blood in the potential space between retinal pigment epithelium (RPE) and neurosensory retinal in the macula. Pneumatic displacement is one of the management procedures that is shifting the bleeding under the macula by injecting gas. The purpose of writing this case report is to report Sub-macula Bleeding cases which are managed with Pneumatic Displacement. Case Presentation. A 55-year-old woman, housewife, was living outside the city, came with complaints of a sudden blurred left eye since 2 weeks ago. At the ophthalmological examination, 612 pH (-) right eye vision and 1/300 left eye vision were obtained. On examination of the anterior segment in the right and left eye the lens is cloudy with grade I nuclear morphology. The image of the right eye fundoscopy is within normal limits, whereas in the left eye a macula is found: reflex fovea (-) blood (+). The choice of therapy in this patient is carried out by Pneumatic Displacement by injecting C3F8 gas, which aims to shift the bleeding under the macula by injecting gas. Conclusion. Pneumatic Displacement is a simple procedure, not too invasive, and the risk of intraocular complications is smaller. Pneumatic Displacement aims to shift blood from under the macula to other parts of the retina that are less vital for vision.
{"title":"Management of Submacula Bleeding with Pneumatic Displacement","authors":"Shaelva Lassa Sabatini, Ak Ansyori, Ramzi Amin","doi":"10.37275/sjo.v2i1.26","DOIUrl":"https://doi.org/10.37275/sjo.v2i1.26","url":null,"abstract":"Introduction. Submacular hemorrhage is defined as the presence of blood in the potential space between retinal pigment epithelium (RPE) and neurosensory retinal in the macula. Pneumatic displacement is one of the management procedures that is shifting the bleeding under the macula by injecting gas. The purpose of writing this case report is to report Sub-macula Bleeding cases which are managed with Pneumatic Displacement. \u0000Case Presentation. A 55-year-old woman, housewife, was living outside the city, came with complaints of a sudden blurred left eye since 2 weeks ago. At the ophthalmological examination, 612 pH (-) right eye vision and 1/300 left eye vision were obtained. On examination of the anterior segment in the right and left eye the lens is cloudy with grade I nuclear morphology. The image of the right eye fundoscopy is within normal limits, whereas in the left eye a macula is found: reflex fovea (-) blood (+). The choice of therapy in this patient is carried out by Pneumatic Displacement by injecting C3F8 gas, which aims to shift the bleeding under the macula by injecting gas. \u0000Conclusion. Pneumatic Displacement is a simple procedure, not too invasive, and the risk of intraocular complications is smaller. Pneumatic Displacement aims to shift blood from under the macula to other parts of the retina that are less vital for vision.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"129 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74146044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Objective: To determine the relationship of serum IgE levels and age-related cataract at the Special Eye Hospital in Palembang. Methods: An observational study with cross-sectional design study was undertaken in October 2018 to May 2019 at the Special Eye Hospital in Palembang. There were 86 patients who met the inclusion and exclusion criteria. The independent variable in this study is the level of serum immunoglobulin E and the dependent variable is senile cataract. The data analysis has been done with diagnostic research by SPSS version 20.0 (SPSS, Inc Chicago, Illinois). Results: Thirty five people suffered from senile cataracts and fifty one people did not suffer from cataracts. The mean IgE level in senile cataract patients was 5.129 ± 1.588 ng /mL while in patients without cataracts it was 5.001 ± 1.564 ng/mL. There was no difference in IgE levels between senile cataract patients and patients without cataracts (p = 0.891). With statistical analysis using the ROC curve it was found that the IgE concentration cut off point was 5.046 ng/mL. There were 54.3% of senile cataract patients and 51% of patients without cataracts who had IgE levels > 5.046 ng/mL. Patients with IgE levels > 5.046 had an almost equal risk of senile cataracts compared to patients with IgE levels <5.046 (PR = 1.142 (CI95% 0.482 - 2.705; p = 0.935). Conclusion: There is no significant relationship between IgE levels and the incidence of senile cataracts.
{"title":"The Relationship Between Immunoglobulin E Serum Levels And Age-Related Cataract","authors":"Meidina Rahmah, Alie Solahuddin","doi":"10.37275/sjo.v2i2.35","DOIUrl":"https://doi.org/10.37275/sjo.v2i2.35","url":null,"abstract":"ABSTRACT \u0000 \u0000Objective: To determine the relationship of serum IgE levels and age-related cataract at the Special Eye Hospital in Palembang. \u0000Methods: An observational study with cross-sectional design study was undertaken in October 2018 to May 2019 at the Special Eye Hospital in Palembang. There were 86 patients who met the inclusion and exclusion criteria. The independent variable in this study is the level of serum immunoglobulin E and the dependent variable is senile cataract. The data analysis has been done with diagnostic research by SPSS version 20.0 (SPSS, Inc Chicago, Illinois). \u0000Results: Thirty five people suffered from senile cataracts and fifty one people did not suffer from cataracts. The mean IgE level in senile cataract patients was 5.129 ± 1.588 ng /mL while in patients without cataracts it was 5.001 ± 1.564 ng/mL. There was no difference in IgE levels between senile cataract patients and patients without cataracts (p = 0.891). With statistical analysis using the ROC curve it was found that the IgE concentration cut off point was 5.046 ng/mL. There were 54.3% of senile cataract patients and 51% of patients without cataracts who had IgE levels > 5.046 ng/mL. Patients with IgE levels > 5.046 had an almost equal risk of senile cataracts compared to patients with IgE levels <5.046 (PR = 1.142 (CI95% 0.482 - 2.705; p = 0.935). \u0000Conclusion: There is no significant relationship between IgE levels and the incidence of senile cataracts.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78688863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Optical Coherence Tomography Angiography (OCTA) is a new high-resolution imaging method for visualizing retinal and choroidal circulation without any dye injection By detecting intravascular flow quickly when needed and being able to repeat images, as often as needed, without risk to patients, doctors will value OCTA as one of the most important applications of OCT imaging because of its ability to offer precise visualization of intravascular flow in the inner retina layer and outside, as well as the inner choroid. OCTA uses high-speed structural OCT imaging and provides three-dimensional data about microvascular structures, enabling visualization of the en face apart from the retinal capillary plexus and choriocapillaris, combined with co-registered en face and cross-sectional structural OCT. Although OCTA is a strong modality, it can have imaging artifacts and provide information that is inherently more complex than structural OCT alone. Successful interpretation of OCTA findings requires an understanding of how OCTA works, the relationship of various ocular pathologies to its angiographic features, and integrated assessment of angiographic and structural OCT data.
{"title":"Optical Coherence Tomography Angiography","authors":"Dita Mintardi, Ak Ansyori, Ramzi Amin","doi":"10.37275/sjo.v2i1.20","DOIUrl":"https://doi.org/10.37275/sjo.v2i1.20","url":null,"abstract":"Optical Coherence Tomography Angiography (OCTA) is a new high-resolution imaging method for visualizing retinal and choroidal circulation without any dye injection By detecting intravascular flow quickly when needed and being able to repeat images, as often as needed, without risk to patients, doctors will value OCTA as one of the most important applications of OCT imaging because of its ability to offer precise visualization of intravascular flow in the inner retina layer and outside, as well as the inner choroid. OCTA uses high-speed structural OCT imaging and provides three-dimensional data about microvascular structures, enabling visualization of the en face apart from the retinal capillary plexus and choriocapillaris, combined with co-registered en face and cross-sectional structural OCT. Although OCTA is a strong modality, it can have imaging artifacts and provide information that is inherently more complex than structural OCT alone. Successful interpretation of OCTA findings requires an understanding of how OCTA works, the relationship of various ocular pathologies to its angiographic features, and integrated assessment of angiographic and structural OCT data.","PeriodicalId":22012,"journal":{"name":"Sriwijaya Journal of Ophthalmology","volume":"146 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80567318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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