Pub Date : 2024-02-01Epub Date: 2024-02-28DOI: 10.18295/squmj.2.2024.012
Francisco J D Torre-Gomar, Javier Gimeno-Castillo, Amaia Sagasta-Lacalle, Itziar Arrue-Michelena
{"title":"Primary Cutaneous Gamma/Delta T-cell Lymphoma Simulating Lupus Erythematosus Panniculitis: What do we know about this aggressive mimicker?","authors":"Francisco J D Torre-Gomar, Javier Gimeno-Castillo, Amaia Sagasta-Lacalle, Itziar Arrue-Michelena","doi":"10.18295/squmj.2.2024.012","DOIUrl":"10.18295/squmj.2.2024.012","url":null,"abstract":"","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"24 1","pages":"141-142"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01Epub Date: 2024-02-28DOI: 10.18295/squmj.2.2024.009
B Jayakrishnan, Hari Kishan Gonuguntla
{"title":"Oxygenation during Endobronchial Ultrasound: Where do we stand?","authors":"B Jayakrishnan, Hari Kishan Gonuguntla","doi":"10.18295/squmj.2.2024.009","DOIUrl":"10.18295/squmj.2.2024.009","url":null,"abstract":"","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"24 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01Epub Date: 2024-02-28DOI: 10.18295/squmj.5.2023.036
Aref Zribi, Reem Al Mazroui, Raza Sayani, Ikram A Burney
Choriocarcinoma (CC) is a malignant neoplasm of the trophoblastic tissue, with a potential to metastasise to distant organs. Limited case of gestational CC develops after a long latent period. We report a 52-year-old postmenopausal woman who developed metastatic choriocarcinoma presumably of gestational origin, 8 years after the last pregnancy and 2 years after the last menstrual period. The patient was brought to the emergency room of a tertiary care centre in Muscat, Oman, in 2022 and was diagnosed with CC metastatic to the brain, spleen, lung and the kidney. The β-human chorionic gonadotrophin level was found to be raised (1,292,867 mIU/mL). The International Federation of Gynecologic Oncology risk score was calculated to be 14 (very high risk). The patient was initially treated with whole-brain radiotherapy and splenic artery embolisation because of a hemoperitoneum. Afterwards the patient received systemic treatment using the standard EMA/CO regimen till complete serological remission.
{"title":"An Unusual Presentation of Choriocarcinoma in a Postmenopausal Woman: A case report.","authors":"Aref Zribi, Reem Al Mazroui, Raza Sayani, Ikram A Burney","doi":"10.18295/squmj.5.2023.036","DOIUrl":"10.18295/squmj.5.2023.036","url":null,"abstract":"<p><p>Choriocarcinoma (CC) is a malignant neoplasm of the trophoblastic tissue, with a potential to metastasise to distant organs. Limited case of gestational CC develops after a long latent period. We report a 52-year-old postmenopausal woman who developed metastatic choriocarcinoma presumably of gestational origin, 8 years after the last pregnancy and 2 years after the last menstrual period. The patient was brought to the emergency room of a tertiary care centre in Muscat, Oman, in 2022 and was diagnosed with CC metastatic to the brain, spleen, lung and the kidney. The β-human chorionic gonadotrophin level was found to be raised (1,292,867 mIU/mL). The International Federation of Gynecologic Oncology risk score was calculated to be 14 (very high risk). The patient was initially treated with whole-brain radiotherapy and splenic artery embolisation because of a hemoperitoneum. Afterwards the patient received systemic treatment using the standard EMA/CO regimen till complete serological remission.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":" ","pages":"135-138"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49309549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01Epub Date: 2024-02-28DOI: 10.18295/squmj.5.2023.035
Ayida Al Khalili, Elsa Maciagowski, Khue Nguyen, Kevin A Watters
Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in a setting of immunosuppression. It is caused by a novel human polymoavirus, TS-associated polyomavirus. Reduction of immunosuppression and/or anti-viral therapy is the main therapeutic strategies used to treat such cases. We report a biopsy-proven case of TS in a male renal transplant patient who presented to a dermatology outpatient clinic in Montreal, Canada, in 2015. He was managed with valgancyclovir with no obvious response. Subsequently, a trial of topical imiquimod was commenced. Awareness of TS can prompt early diagnosis and management to prevent possible complications.
{"title":"Trichodysplasia Spinulosa.","authors":"Ayida Al Khalili, Elsa Maciagowski, Khue Nguyen, Kevin A Watters","doi":"10.18295/squmj.5.2023.035","DOIUrl":"10.18295/squmj.5.2023.035","url":null,"abstract":"<p><p>Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in a setting of immunosuppression. It is caused by a novel human polymoavirus, TS-associated polyomavirus. Reduction of immunosuppression and/or anti-viral therapy is the main therapeutic strategies used to treat such cases. We report a biopsy-proven case of TS in a male renal transplant patient who presented to a dermatology outpatient clinic in Montreal, Canada, in 2015. He was managed with valgancyclovir with no obvious response. Subsequently, a trial of topical imiquimod was commenced. Awareness of TS can prompt early diagnosis and management to prevent possible complications.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":" ","pages":"131-134"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46527999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01Epub Date: 2024-02-28DOI: 10.18295/squmj.7.2023.045
Ahmed Al-Maskari, Qasim Al-Maamari, Mariya Al-Abdali, Hajer Al-Shaaibi, Sunil K Nadar
Objectives: This study aimed to evaluate the level of adherence to medication among patients with ischaemic heart disease (IHD) in Oman and assess the related factors.
Methods: This cross-sectional questionnaire-based study among patients with IHD attending the outpatient clinic at Sultan Qaboos University Hospital, Muscat, Oman, was performed between January and December 2021.
Results: A total of 105 patients (mean age = 49.9 ± 11.1 years, 78.1% male) were recruited. Most of the patients (80%) reported taking the medications by themselves; 77 (73.3%) patients said that over the preceding 2 weeks, they had missed at least 3 doses of their medication. The reasons for missing the medications included forgetting (100%), having to take too many tablets (57%), feeling that the tablets are not effective (48%) and having to take the tablets too often each day (23%). The factors responsible for patients failing to take medications could not be identified.
Conclusion: Medication adherence was low among patients with IHD in Oman, with high pill burden being the most common reason for non-adherence. Physicians must bear this in mind when reviewing patients.
{"title":"Adherence to Medications in Patients with Ischaemic Heart Disease in Oman.","authors":"Ahmed Al-Maskari, Qasim Al-Maamari, Mariya Al-Abdali, Hajer Al-Shaaibi, Sunil K Nadar","doi":"10.18295/squmj.7.2023.045","DOIUrl":"10.18295/squmj.7.2023.045","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the level of adherence to medication among patients with ischaemic heart disease (IHD) in Oman and assess the related factors.</p><p><strong>Methods: </strong>This cross-sectional questionnaire-based study among patients with IHD attending the outpatient clinic at Sultan Qaboos University Hospital, Muscat, Oman, was performed between January and December 2021.</p><p><strong>Results: </strong>A total of 105 patients (mean age = 49.9 ± 11.1 years, 78.1% male) were recruited. Most of the patients (80%) reported taking the medications by themselves; 77 (73.3%) patients said that over the preceding 2 weeks, they had missed at least 3 doses of their medication. The reasons for missing the medications included forgetting (100%), having to take too many tablets (57%), feeling that the tablets are not effective (48%) and having to take the tablets too often each day (23%). The factors responsible for patients failing to take medications could not be identified.</p><p><strong>Conclusion: </strong>Medication adherence was low among patients with IHD in Oman, with high pill burden being the most common reason for non-adherence. Physicians must bear this in mind when reviewing patients.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":" ","pages":"109-114"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41979351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01Epub Date: 2024-02-28DOI: 10.18295/squmj.2.2024.011
Salma Al-Kharusi, Sharouq Al-Khatri
{"title":"The Clinical and Paraclinical Manifestations of Tuberous Sclerosis in an Omani Female Patient.","authors":"Salma Al-Kharusi, Sharouq Al-Khatri","doi":"10.18295/squmj.2.2024.011","DOIUrl":"10.18295/squmj.2.2024.011","url":null,"abstract":"","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"24 1","pages":"139-140"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01Epub Date: 2024-02-28DOI: 10.18295/squmj.2.2024.013
Sounira Mehri, Sinda Zarrouk, Josef Finsterer
{"title":"Re: Propofol in Triple Trouble Kearns-Sayre Syndrome, Dyggve-Melchior-Clausen Syndrome, and Chromosome-9 Inversion.","authors":"Sounira Mehri, Sinda Zarrouk, Josef Finsterer","doi":"10.18295/squmj.2.2024.013","DOIUrl":"10.18295/squmj.2.2024.013","url":null,"abstract":"","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"24 1","pages":"146-148"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.18295/squmj.12.2023.092
Atefeh Yas, Fatemeh Z Karimi, T. Khadivzadeh
Adolescent mothers face numerous challenges while breastfeeding. The purpose of the study was to assess the breastfeeding needs of adolescent mothers. Two researchers independently searched the databases Web of Science, PubMed, Scopus, Cochrane Library, SID, and Magiran. The initial search yielded 2290 studies, of which 41 were eventually included in this systematic review. Breastfeeding requirements of adolescent mothers were categorized into eight categories: 1. Social support from health care providers, partners, and families; 2. School support for breastfeeding mothers, 3. Receiving breastfeeding counseling based on cultural sensitivities, 4. Educational assistance from health providers for adolescent mothers' families 5. Changing harmful cultural values and judgments about adolescent mothers' breastfeeding, 6. Additional home or outpatient visits in the days following hospital discharge; 7. Peer support and peer counseling, 8. Economic needs. To promote breastfeeding, policymakers and healthcare providers ought to devise specifically tailored programs and interventions to cater to the specific requirements of mothers. Keywords: Breastfeeding; Adolescent Mothers; Infant Feeding; Need; Qualitative Study.
未成年母亲在母乳喂养过程中面临诸多挑战。本研究旨在评估未成年母亲的母乳喂养需求。两名研究人员独立检索了 Web of Science、PubMed、Scopus、Cochrane Library、SID 和 Magiran 等数据库。最初的搜索结果是 2290 项研究，其中 41 项最终被纳入本系统综述。青少年母亲的母乳喂养要求被分为八类：1.来自医护人员、伴侣和家庭的社会支持；2.学校对母乳喂养母亲的支持；3.接受基于文化敏感性的母乳喂养咨询；4.医护人员对未成年母亲家庭的教育帮助；5.改变有害的文化价值观和判断。改变对未成年母亲母乳喂养有害的文化价值观和判断； 6. 出院后几天内的额外家访或门诊； 7. 同龄人支持和同龄人咨询； 8.经济需求。 为了促进母乳喂养，政策制定者和医疗服务提供者应该制定专门的计划和干预措施，以满足母亲们的特殊要求。 关键词母乳喂养；未成年母亲；婴儿喂养；需求；定性研究。
{"title":"Breastfeeding Needs in Adolescent Mothers","authors":"Atefeh Yas, Fatemeh Z Karimi, T. Khadivzadeh","doi":"10.18295/squmj.12.2023.092","DOIUrl":"https://doi.org/10.18295/squmj.12.2023.092","url":null,"abstract":"Adolescent mothers face numerous challenges while breastfeeding. The purpose of the study was to assess the breastfeeding needs of adolescent mothers. Two researchers independently searched the databases Web of Science, PubMed, Scopus, Cochrane Library, SID, and Magiran. The initial search yielded 2290 studies, of which 41 were eventually included in this systematic review. Breastfeeding requirements of adolescent mothers were categorized into eight categories: 1. Social support from health care providers, partners, and families; 2. School support for breastfeeding mothers, 3. Receiving breastfeeding counseling based on cultural sensitivities, 4. Educational assistance from health providers for adolescent mothers' families 5. Changing harmful cultural values and judgments about adolescent mothers' breastfeeding, 6. Additional home or outpatient visits in the days following hospital discharge; 7. Peer support and peer counseling, 8. Economic needs. To promote breastfeeding, policymakers and healthcare providers ought to devise specifically tailored programs and interventions to cater to the specific requirements of mothers. Keywords: Breastfeeding; Adolescent Mothers; Infant Feeding; Need; Qualitative Study.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"62 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139169510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.18295/squmj.12.2023.090
Salma T Al Kharusi, Aya A Al Lamki, Raqiya Al Rajaibi, Zakiya I Al Ajmi
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign, vasoproliferative tumour. We report a 25-year-old female patient who reported in 2021 to the dermatology clinic, with multiple, grouped, erythematous dome-shaped papules and nodules of 6 months duration on the left temporo-occipital region. Biopsy findings were consistent with a diagnosis of ALHE with evidence of Demodex mite infestation in the sebaceous ducts. The patient demonstrated significant improvement following 7 weeks of treatment with multiple cryotherapy sessions and topical application of metronidazole gel. This case suggests that scalp demodicosis may represent a novel trigger for the development of ALHE. Keywords: Angiolymphoid Hyperplasia with Eosinophilia; Mite; Infestation; Scalp; Kimura disease; Cryosurgery; Metronidazole; Case Report.
{"title":"Successful Treatment of Angiolymphoid Hyperplasia with Eosinophilia Associated with Scalp Demodicosis Using Cryotherapy and Topical Metronidazole","authors":"Salma T Al Kharusi, Aya A Al Lamki, Raqiya Al Rajaibi, Zakiya I Al Ajmi","doi":"10.18295/squmj.12.2023.090","DOIUrl":"https://doi.org/10.18295/squmj.12.2023.090","url":null,"abstract":"Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign, vasoproliferative tumour. We report a 25-year-old female patient who reported in 2021 to the dermatology clinic, with multiple, grouped, erythematous dome-shaped papules and nodules of 6 months duration on the left temporo-occipital region. Biopsy findings were consistent with a diagnosis of ALHE with evidence of Demodex mite infestation in the sebaceous ducts. The patient demonstrated significant improvement following 7 weeks of treatment with multiple cryotherapy sessions and topical application of metronidazole gel. This case suggests that scalp demodicosis may represent a novel trigger for the development of ALHE. \u0000Keywords: Angiolymphoid Hyperplasia with Eosinophilia; Mite; Infestation; Scalp; Kimura disease; Cryosurgery; Metronidazole; Case Report.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"17 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138994338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.18295/squmj.12.2023.083
Al Zahra Al Hashmi, Ethar Al Fazari, Mustafa Al Ward, Reema Al Masruri, Shahad Al Balushi, Mohammed Al Mutani, Ahmed Al Ghaithi, Wafa Al Baluki
Objective: Despite the numerous advances in management strategies, treating osteomyelitis in individuals with sickle cell disease remains a significant challenge, leading to severe long-term consequences. This study aimed to assess the key factors potentially linked to a complex progression of osteomyelitis in patients diagnosed with sickle cell disease. Methods: A cohort of thirty-four patients was identified, and their progress was monitored over a span of twelve months, during a ten-year period (2010-2020). The variables under investigation encompassed demographic and clinical traits, laboratory analyses, imaging data, as well as the strategies employed for treatment. Results: The risk prediction model has pinpointed five factors (severity of sickle cell disease, involvement of lower limbs, presence of bacteraemia, MRI findings, and utilization of surgical debridement) that exhibited an Area Under the Curve (AUC) exceeding 0.7. Causative organisms were identified in 9 out of the total cases, constituting 26.47% of the patient cohort. Among the 34 patients, 17 displayed a severe course of sickle cell disease (AUC 7.88), with MRI being highlighted as a valuable contributing factor (AUC 7.88). Furthermore, thirteen patients (38.2%) underwent surgical debridement, a procedure that yielded a statistically significant P-value of 0.012 and an AUC of 0.714. Conclusion: Osteomyelitis within the context of severe sickle cell disease, particularly when accompanied by lower extremity infection, bacteraemia, and positive MRI findings, and necessitating surgical debridement, emerges as a cluster of risk factors predisposing individuals to osteomyelitis relapse and a more intricate disease trajectory. Keywords: Sickle cell disease, Osteomyelitis, Disease Severity, Debridement, bacteraemia
{"title":"Predictors of Developing a Complex Course of Osteomyelitis in Patients with Sickle Cell Anaemia","authors":"Al Zahra Al Hashmi, Ethar Al Fazari, Mustafa Al Ward, Reema Al Masruri, Shahad Al Balushi, Mohammed Al Mutani, Ahmed Al Ghaithi, Wafa Al Baluki","doi":"10.18295/squmj.12.2023.083","DOIUrl":"https://doi.org/10.18295/squmj.12.2023.083","url":null,"abstract":"Objective: Despite the numerous advances in management strategies, treating osteomyelitis in individuals with sickle cell disease remains a significant challenge, leading to severe long-term consequences. This study aimed to assess the key factors potentially linked to a complex progression of osteomyelitis in patients diagnosed with sickle cell disease. Methods: A cohort of thirty-four patients was identified, and their progress was monitored over a span of twelve months, during a ten-year period (2010-2020). The variables under investigation encompassed demographic and clinical traits, laboratory analyses, imaging data, as well as the strategies employed for treatment. Results: The risk prediction model has pinpointed five factors (severity of sickle cell disease, involvement of lower limbs, presence of bacteraemia, MRI findings, and utilization of surgical debridement) that exhibited an Area Under the Curve (AUC) exceeding 0.7. Causative organisms were identified in 9 out of the total cases, constituting 26.47% of the patient cohort. Among the 34 patients, 17 displayed a severe course of sickle cell disease (AUC 7.88), with MRI being highlighted as a valuable contributing factor (AUC 7.88). Furthermore, thirteen patients (38.2%) underwent surgical debridement, a procedure that yielded a statistically significant P-value of 0.012 and an AUC of 0.714. Conclusion: Osteomyelitis within the context of severe sickle cell disease, particularly when accompanied by lower extremity infection, bacteraemia, and positive MRI findings, and necessitating surgical debridement, emerges as a cluster of risk factors predisposing individuals to osteomyelitis relapse and a more intricate disease trajectory. \u0000Keywords: Sickle cell disease, Osteomyelitis, Disease Severity, Debridement, bacteraemia","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"63 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138957029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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