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Schwannoma of the Appendix Mimicking a Metastatic Breast Cancer 模仿转移性乳腺癌的阑尾许旺瘤
Q3 Medicine Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.041
Z. Al-ishaq, Alonood Al-Sulaimani, Badriya Al-Qassabi, Fathiya AlRahbi, Khalid Al Baimani, Jawa Z. Muhammad, A. Aljarrah
Metastatic breast cancer (MBC) represents 5-10% of newly diagnosed breast cancer cases, referred to as de novo stage IV MBC. Distinguishing a distant lesion in breast cancer patients can be challenging. Therefore, obtaining a histopathological confirmation of a metastasis is advisable, as a suspicious metastatic lesion may turn out to be benign or exhibit different immunohistochemistry compared to the primary site. In this case, we describe a woman undergoing staging scans for newly diagnosed breast cancer, where radiological findings suggested appendix metastasis. However, subsequent laparoscopic appendicectomy revealed an appendicular schwannoma, confirmed through immunohistochemistry. The patient then received curative-intent breast cancer treatment. With the increasing use of advanced staging scans in breast cancer, clinicians should thoroughly investigate and confirm metastatic disease, especially in uncommon metastatic sites, before initiating treatment. Keywords: Schwannoma, metastasis, breast cancer, appendix.
转移性乳腺癌(MBC)占新诊断乳腺癌病例的 5-10%,被称为新发 IV 期 MBC。在乳腺癌患者中区分远处病灶是一项挑战。因此,最好对转移灶进行组织病理学确认,因为可疑的转移灶可能是良性的,或者表现出与原发部位不同的免疫组化。在本病例中,我们描述了一名妇女因新确诊的乳腺癌接受分期扫描,放射学检查结果显示阑尾转移。然而,随后的腹腔镜阑尾切除术发现了阑尾裂孔瘤,并通过免疫组化证实了这一点。患者随后接受了乳腺癌根治性治疗。随着乳腺癌晚期分期扫描的应用越来越广泛,临床医生在开始治疗前应彻底检查并确认转移性疾病,尤其是不常见的转移部位。关键词许旺瘤 转移 乳腺癌 盲肠
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引用次数: 0
Prevalence, clinico-laboratory features and outcome of paediatric scrub typhus cases in a tertiary care centre in Eastern India 印度东部一家三级护理中心儿科恙虫病病例的发病率、临床实验室特征和治疗结果
Q3 Medicine Pub Date : 2024-06-13 DOI: 10.18295/squmj.6.2024.032
R. Murmu, Gobinda Mondal, Koushik Biswas, Ashok K Bala
Objective: Scrub typhus is the most common rickettsial disease in India, caused by Orientia tsutsugamushi, and transmitted by chigger mites. Previously reported in South India, but the resurgence of cases is currently reported in Eastern India. This study aimed to estimate the prevalence and describe the clinico-laboratory profile of scrub typhus in paediatric patients (1-12 years old) in Eastern India. Methods: A prospective observational study was conducted from January to December 2019 in a paediatric tertiary care centre in Kolkata. All acute undifferentiated febrile illness cases (1-12 years) were tested for scrub typhus serology by ELISA. Demographic details, clinical features, laboratory findings, complications and treatment outcomes of scrub typhus patients were extracted in Microsoft Excel spreadsheet and further analysed. Results: The prevalence of scrub typhus among acute febrile illness patients was 4.5 %. The mean age of patients was 5.22 years and the majority (64.2 %) had a fever for the last 7-14 days. Gastrointestinal symptoms like vomiting (43.3 %) and pain abdominal (32.8 %) were frequently seen. Major clinical signs were hepatomegaly (41.8 %) and splenomegaly (31.3 %). Complication was observed in 74.6 %, with thrombocytopenia (40.3 %) and meningoencephalitis (29.9 %) being more frequent. The case fatality rate was 1.5 %. Conclusions: Classical eschar was absent in three-fourth of our patients, hence we advocate laboratory scrub typhus testing for all suspected cases in endemic region. Thrombocytopenia and meningoencephalitis were prominent complications in our study. Prompt treatment with doxycycline and/or azithromycin could prevent complications and reduce mortality. Keywords: Hospital Stay; Hospitalization, patient discharge; General Internal Medicine
目的:恙虫病是印度最常见的立克次体病:恙虫病是印度最常见的立克次体病,由Orientia tsutsugamushi引起,通过恙螨传播。以前在南印度曾有报道,但目前在印度东部又有病例报告。本研究旨在估计恙虫病在印度东部儿童患者(1-12 岁)中的流行率,并描述其临床-实验室概况。研究方法2019年1月至12月,在加尔各答的一家儿科三级护理中心开展了一项前瞻性观察研究。所有急性未分化发热病例(1-12 岁)均通过 ELISA 进行了恙虫病血清学检测。在 Microsoft Excel 电子表格中提取恙虫病患者的详细人口统计学资料、临床特征、实验室检查结果、并发症和治疗结果,并进行进一步分析。结果恙虫病在急性发热病人中的发病率为 4.5%。患者的平均年龄为 5.22 岁,大多数患者(64.2%)在过去 7-14 天内都有发烧症状。呕吐(43.3%)和腹痛(32.8%)等胃肠道症状经常出现。主要临床表现为肝脏肿大(41.8%)和脾脏肿大(31.3%)。74.6%的患者出现并发症,其中血小板减少(40.3%)和脑膜脑炎(29.9%)更为常见。病死率为 1.5%。结论:四分之三的患者没有典型的炭化现象,因此我们提倡在恙虫病流行地区对所有疑似病例进行实验室恙虫病检测。在我们的研究中,血小板减少和脑膜脑炎是主要的并发症。及时使用强力霉素和/或阿奇霉素治疗可预防并发症并降低死亡率。关键词:住院住院、住院、出院、普通内科
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引用次数: 0
Congenital Blood Cyst of a Child: A case report and review of literature. 儿童先天性血囊肿
Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2024-05-27 DOI: 10.18295/squmj.5.2023.037
Rachid Kaddoura, Issam El Rassi, Zainab Al Awadi, Mohamed Kasem

Blood-filled cysts of the heart valves are frequently reported at postpartum autopsies of infants. They are seen as round nodules mostly in the paediatric age group in infants less than 2 months of age and disappear spontaneously within 6 months of life. We report a unique case of an 11-month-old girl who presented at a tertiary healthcare hospital in 2022 with a blood-filled cyst on the posterior leaflet of the pulmonary valve that was successfully treated. This case report highlights the characteristics and course of a paediatric patient with blood-filled cysts. Further studies are yet needed to better understand the diagnostic approaches to blood-filled cysts as well as treatment modalities to fill the gap in clinical settings.

婴儿产后尸检时经常报告心脏瓣膜充满血液的囊肿。它们被视为圆形结节,主要发生在两个月以下婴儿的儿科年龄组,并在六个月内自发消失。我们报告了一个独特的病例,一个11个月大的女孩在肺动脉瓣后叶上有一个充满血液的囊肿,并得到了成功的治疗。本病例报告重点介绍了一名儿童囊肿充血患者的特点和病程。还需要进一步的研究来更好地了解充满血液的囊肿的诊断方法以及填补临床空白的治疗模式。关键词:充血囊肿;肺动脉瓣;肺动脉;儿科;心脏肿瘤;心脏病学。
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引用次数: 0
Peri-ictal Water Drinking in an Omani Patient with Bilateral Mesial Temporal Sclerosis. 阿曼双侧内侧颞叶硬化患者围周饮水
Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2024-05-27 DOI: 10.18295/squmj.5.2023.038
Younis Al-Mufargi, Haifa Alabri, Arunodaya Gujjar

Peri-ictal water drinking (PIWD) is a rare vegetative manifestation of temporal lobe epilepsy without a definite lateralisation value. We report a case of PIWD in a 22-year-old Omani male patient with post-concussion syndrome and epilepsy presented to a tertiary care hospital in Muscat, Oman, in 2021 for evaluation of paroxysmal events. His behaviour of PIWD was misinterpreted by his family until characterised in the epilepsy-monitoring unit as a manifestation of epilepsy that was treated medically. To the best of the authors' knowledge, this is the second reported case in the region.

发作期饮水(PIWD)是颞叶癫痫的一种罕见的植物性表现,没有明确的侧化价值。我们报告了一例PIWD病例,该病例发生在一名22岁的阿曼男子身上,他患有脑震荡后综合征和癫痫,于2021年被送往阿曼马斯喀特的一家三级护理医院,以评估阵发性事件。他的PIWD行为被他的家人误解,直到在癫痫监测室被定性为癫痫的表现,并接受了医学治疗。据我们所知,这是我们地区报告的第二例病例。关键词:围产期饮水,冰吐,癫痫,自主性。
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引用次数: 0
Efficacy of Ropivacaine for Sub-Arachnoid Block in Patients with Recent History of Scorpion Sting: A case series. 罗哌卡因用于蛛网膜下腔阻滞治疗近期有蝎毒刺史患者的疗效
Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2024-05-27 DOI: 10.18295/squmj.7.2023.046
Saurabh Trivedi, Hemendra Bhardwaj, Tapan K Sahoo, Seema Gupta

Failure of sub-arachnoid block (SAB), due to resistance to bupivacaine after a recent scorpion sting can lead to multiple block attempts and subsequent conversion to general anaesthesia. We report this case series of 10 patients with successful SAB with newly launched 0.75% hyperbaric ropivacaine, in patients with recent scorpion sting. Thus, intrathecal hyperbaric ropivacaine may be considered as the local anaesthetic agent of choice in patients with scorpion sting to prevent failure of SAB.

最近一次蝎子蜇伤后,由于对布比卡因的抵抗,导致蛛网膜下阻滞(SAB)失败,可导致多次阻滞尝试,随后转为全身麻醉。我们报告了10例最近有蝎子蜇伤的患者使用新推出的0.75%高压罗哌卡因成功治疗SAB的病例系列。因此,鞘内高压罗哌卡因可作为蝎子蜇伤患者局部麻醉的选择,以防止SAB失败。关键词:Bupivacaine;Ropivacaine;蝎子刺痛;脊髓麻醉。
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引用次数: 0
Ramsay Hunt Syndrome Associated with Varicella-Zoster Virus Encephalitis in a Child. Ramsay-Hunt综合征并发儿童水痘带状疱疹病毒性脑炎
Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2022-11-22 DOI: 10.18295/squmj.3.2023.020
Eman Y Ahmed, Hatem Al Rawahi, Fatema Al Amrani, Laila Al Masaoudi, Laila Al Yazidi

Ramsay Hunt syndrome (RHS) is a triad of peri-auricular pain, ipsilateral facial nerve palsy and vesicular rash around the ear pinna. It is caused by reactivation of varicella-zoster virus (VZV) that lies dormant in the geniculate ganglia. It can be complicated by VZV encephalitis rarely. We report the case of an 8-year-old previously healthy boy who presented to a tertiary care hospital in Muscat, Oman in 2021 with fever, progressive left ear pain, vesicular rash around his ear pinna and left-sided facial nerve palsy. His course was complicated by VZV encephalitis where he was managed with intravenous (IV) acyclovir and IV corticosteroids. He improved significantly and was asymptomatic with a normal neurology examination at the 6-months follow-up.

拉姆齐亨特综合征(RHS)是耳廓周围疼痛、同侧面神经麻痹和耳廓周围水疱疹的三联征。它是由潜伏在膝状神经节中的水痘带状疱疹病毒(VZV)重新激活引起的。很少并发VZV脑炎。我们报告了一名8岁的健康男孩,他于2021年在阿曼马斯喀特的一家三级保健医院就诊,表现为发烧、进行性左耳疼痛、耳廓周围水疱疹和左侧面神经麻痹。他的病程因VZV脑炎而复杂化,并给予静脉注射阿昔洛韦和静脉注射皮质类固醇。在6个月的随访中,他的症状明显改善,无症状,神经学检查正常。关键词:水痘带状疱疹病毒;拉姆齐·亨特综合征;脑炎;的孩子。
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引用次数: 0
Protracted Chemical Peritonitis Following Laparoscopy for Dermoid Cyst: A management dilemma. 腹腔镜治疗乙状囊肿后的顽固性化学性腹膜炎
Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2024-02-28 DOI: 10.18295/squmj.3.2023.019
Miriam G Fenn, Sreedharan V Koliyadan, Lovina Machado, Shahila Sheik, Nihal Al Riyami

Dermoid cysts are common benign ovarian tumours arising from totipotent germ cells. We report a rare case of chemical peritonitis and prolonged fever following laparoscopic salpingo-oophorectomy for torsion of a large ovarian dermoid and discuss the management of this patient with prolonged hospital stay, antibiotics and anti-inflammatory use, repeated drainage of the collection as well as re-laparotomy. The occurrence of this rare condition can be extremely distressing for the patient and treating surgeon alike, as the recommendations for management are limited. The management of chemical peritonitis may require one or more surgical procedures along with prolonged anti-inflammatory therapy.

皮样囊肿是常见的卵巢良性肿瘤,由全能生殖细胞引起。我们报告了一例罕见的化学性腹膜炎和长期发烧的病例,该病例是在腹腔镜输卵管卵巢切除术治疗大型卵巢皮样扭转后发生的,并讨论了该患者的长期住院、抗生素和抗炎药的使用、反复引流收集物以及再次剖腹手术的处理方法。这种罕见疾病的发生对患者和治疗外科医生来说都是非常痛苦的,因为治疗建议有限。化学性腹膜炎的治疗可能需要一次或多次手术以及长期的抗炎治疗。关键词:腹膜炎、皮样囊肿、腹腔镜检查
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引用次数: 0
Successful Treatment of a Case of Crescentic Glomerulonephritis in a Patient with Primary Peritoneal Carcinoma: A case report. 1例原发性腹膜癌患者新月体肾小球肾炎的成功治疗
Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2022-09-11 DOI: 10.18295/squmj.1.2023.013
Aref Zribi, Amro Nagy, Marwa Al Riyami, Ikram A Burney

Crescentic glomerulonephritis has been associated with several solid tumour malignancies. Only a few cases of nephropathy have been reported in association with tubo-ovarian/peritoneal malignancies. We report a 55-year-old female patient who presented to a tertiary care centre, Muscat, Oman, in 2022. She developed combined immune complex-mediated glomerulonephritis and pauci-immune necrotising crescentic vasculitis simultaneously with the diagnosis of tubo-ovarian/peritoneal cancer. The baseline estimated glomerular filtration rate (eGFR) was 13 mL/min. The patient received two doses of rituximab and three doses of pulse corticosteroids, leading to significant improvement in renal function and the disappearance of her proteinuria. The eGFR improved to >60mL/min; her proteinuria gradually resolved after 10 weeks of treatment. She was then given a combination chemotherapy treatment for tubo-ovarian/peritoneal cancer leading to a normalisation of her CA-125 after three months of therapy.

Crescentic肾小球肾炎(CGN)与几种实体瘤恶性肿瘤有关。只有少数肾病病例与输卵管卵巢/腹膜恶性肿瘤有关。我们描述了一例55岁的女性病例,她在诊断为输卵管-卵巢/腹膜癌症的同时,出现了联合免疫复合物介导的肾小球肾炎和贫血症坏死性新月体血管炎。基线估计肾小球滤过率(eGFR)为13ml/min。患者接受了两剂利妥昔单抗和三剂脉冲皮质类固醇治疗,肾功能显著改善,蛋白尿消失。eGFR改善至>60ml/min,治疗10周后蛋白尿逐渐消退。她可以接受输卵管-卵巢/腹膜癌症的联合化疗治疗,因为在治疗三个月后,她的CA-125恢复正常。关键词:输卵管-卵巢/腹膜癌症,肾小球肾炎,血管炎,化疗。
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引用次数: 0
A Need for Daycare Unit for Sickle Cell Disease Patients in Oman. 阿曼需要为镰状细胞病患者建立日托中心。
Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2024-02-28 DOI: 10.18295/squmj.2.2024.010
Wafa K Al-Majarfi
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引用次数: 0
Primary Cutaneous Gamma/Delta T-cell Lymphoma Simulating Lupus Erythematosus Panniculitis: What do we know about this aggressive mimicker? 原发性皮肤γ/δT细胞淋巴瘤模拟红斑狼疮泛发性炎:我们对这种侵袭性模拟者了解多少?
Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2024-02-28 DOI: 10.18295/squmj.2.2024.012
Francisco J D Torre-Gomar, Javier Gimeno-Castillo, Amaia Sagasta-Lacalle, Itziar Arrue-Michelena
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引用次数: 0
期刊
Sultan Qaboos University Medical Journal
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