Sustainable Chemistry and Pharmacy最新文献_第10页

Heterogeneous catalysts for glycerol and glycol valorization via amination pathways 通过胺化途径实现甘油和乙二醇增值的多相催化剂

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-24 DOI: 10.1016/j.scp.2025.102214

Daniil I. Lashchenko, Petr M. Yeletsky, Darya A. Konovalova, Anton P. Koskin, Sergey A. Stepanenko, Kristina A. Khrustova, Roman G. Kukushkin

The processing of glycerol, as a by-product of biodiesel production, into valuable chemicals is a promising area from both economic and environmental perspectives. One of the approaches to glycerol valorization is the amination of glycerol and its derivatives (for example, propylene glycol), leading to the production of various amines with high added value. Ammonia, as well as primary and secondary amines can act as aminating agents. This review is devoted to the amination processes of various glycols and glycerol using heterogeneous catalysts.

Two main approaches to the catalytic amination process are considered: reductive amination in the presence of hydrogen and direct amination without the introduction of additional hydrogen. These approaches differ not only in the amination process mechanism but also in the nature of the catalyst and the process conditions. The traditional reductive amination catalysts are non-noble transition metals (Ni, Cu, and Co), noble metals (Ru, Pd, Pt, Rh, and Ir), or their combinations deposited on porous supports. Typical examples of direct amination catalysts are zeolites (e.g., Y, ZSM-5, and MOR) and porous acid oxides. For all cases, the general features of the processes of reductive and direct amination are considered, and specific examples are systematized. The key problems in this area are summarized, and the tasks necessary for the successful implementation of the valorization process of glycerol via the catalytic amination process are formulated.

从经济和环境的角度来看，将甘油作为生物柴油生产的副产品加工成有价值的化学品是一个有前途的领域。甘油增值的方法之一是对甘油及其衍生物（例如丙二醇）进行胺化，从而生产出各种具有高附加值的胺。氨以及伯胺和仲胺都可以作为胺化剂。本文综述了各种醇和甘油在非均相催化剂作用下的胺化反应。考虑了催化胺化过程的两种主要方法：在氢存在下的还原胺化和不引入额外氢的直接胺化。这些方法不仅在胺化过程机理上有所不同，而且在催化剂性质和工艺条件上也有所不同。传统的还原胺化催化剂是非贵金属过渡金属（Ni， Cu和Co），贵金属（Ru, Pd, Pt， Rh和Ir），或它们的组合沉积在多孔载体上。直接胺化催化剂的典型例子是沸石（例如，Y， ZSM-5和MOR）和多孔酸氧化物。在所有的情况下，考虑了还原和直接胺化过程的一般特征，并对具体的例子进行了系统化。总结了该领域存在的关键问题，并提出了成功实施催化胺化法甘油增值过程所需要完成的任务。

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引用次数: 0

Novel sustainable strategies to mitigate toxicity of emerging contaminants: cellular and physiological insights from CMIT-exposed mussels treated with insect-based protein hydrolysates 减轻新出现污染物毒性的新型可持续策略：用昆虫蛋白水解物处理的cmit暴露贻贝的细胞和生理见解

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-22 DOI: 10.1016/j.scp.2025.102218

Cristiana Roberta Multisanti , Kristian Riolo , Maria Giovanna Rizzo , Federica Impellitteri , Giuseppe Piccione , Monia Perugini , Alessia Giannetto , Caterina Faggio

The present interest in developing sustainable strategies to mitigate or prevent toxicity of emerging contaminants is attributable to their increasing occurrence in natural ecosystems. Beyond their established roles in the agri-food, feed, and biotechnology sectors, insects are emerging as valuable sources of bioactive compounds, highlighting their recognition as sustainable solutions in nutraceutical and pharmaceutical research. Therefore, the effects of protein hydrolysates from the black soldier fly, Hermetia illucens (BPHs) were evaluated against the toxicity induced by the methylchloroisothiazolinone (CMIT), a widely used biocides belonging to the isothiazolinones class of the biocides. Analyses focused on the modulation of key cellular and physiological parameters in Mytilus galloprovincialis exposed to CMIT (0.01 mg/L), BPHs (0.5 mg/mL), and their mix. Changes in haemocyte functions were assessed through cell viability assays and phagocytosis assay along with the expression of γ-actin; investigation into digestive gland (DG) functionality was carried out by measuring the viability of DG cells and their ability to perform osmoregulation after a hypotonic shock through the Regulatory Volume Decrease video-metric assay (RVD); antioxidant and cytoprotective responses were evaluated through the Cu/ZnSOD, MnSOD, Hsp70, and CYP4Y1 gene expression analysis. Our findings showed that BPHs play a significant protective role against toxicity induced by CMIT in exposed mussels. Significant differences emerged between the control and the CMIT-treated groups, whereas a similar trend was observed between the CTRL and BSPHs-exposed groups. Groups exposed to the combinations (BPHs + CMIT) showed a recovery, suggesting the protective effect of this compound.

目前对制定可持续战略以减轻或防止新出现的污染物的毒性的兴趣是由于它们在自然生态系统中越来越多地出现。除了在农业食品、饲料和生物技术领域的既定作用外，昆虫正在成为生物活性化合物的宝贵来源，突出表明它们在营养保健和制药研究中被视为可持续的解决方案。因此，对黑兵蝇（Hermetia illucens, BPHs）蛋白水解物对甲基氯异噻唑啉酮（methylchloroisothiazolinone， CMIT）的毒性进行了评价。甲基氯异噻唑啉酮是一种广泛使用的杀菌剂，属于异噻唑啉酮类。重点分析了CMIT （0.01 mg/L）、BPHs （0.5 mg/mL）及其混合物对紫贻贝（Mytilus galloprovincialis）关键细胞和生理参数的影响。通过细胞活力测定、吞噬测定以及γ-肌动蛋白的表达来评估血细胞功能的变化；通过调节体积减少视频测量法（RVD）测量消化腺（DG）细胞的活力及其在低渗休克后进行渗透调节的能力，研究了消化腺（DG）的功能；通过Cu/ZnSOD、MnSOD、Hsp70和CYP4Y1基因表达分析，评价其抗氧化和细胞保护作用。我们的研究结果表明，BPHs对暴露于CMIT的贻贝具有显著的保护作用。在对照组和cmit处理组之间出现了显著差异，而在CTRL和bsphs暴露组之间观察到类似的趋势。暴露于组合（BPHs + CMIT）组显示恢复，表明该化合物的保护作用。

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引用次数: 0

Enhanced performance, synergistic mechanism, and better CO2 balance of loess solidification with magnesium cement-fly ash composite stabilizing agent 镁水泥-粉煤灰复合稳定剂对黄土固化性能、增效机理及CO2平衡的改善

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-22 DOI: 10.1016/j.scp.2025.102217

Qi Xu, Dongliang Chen, Xuerui Yan, Chunxi Hai, Yuan Zhou

To address erosion on the ecologically fragile Loess Plateau, this study develops a green alternative to Portland cement-based solidifiers: magnesium oxysulfate cement (MOS) combined with industrial waste fly ash (FA), aligned with green chemistry principles. Physical tests show the MOS-FA composite notably optimizes loess porosity: for the MOS-15 %FA sample, pore volume decreases to 0.233 mL/g (31.4 % porosity, macropores 10.7 %, medium/small pores 28.8 %), and compressive strength rises from 1.3 MPa to 7.1 MPa. Microstructural analysis reveals hydration products (sheet-like Mg(OH)₂, flocculent M-S-H/M-A-S-H/C–S–H, acicular 5·1·7 phase) fill particle pores and form connections, with TG/DTG confirming silicate hydrates. The solidification mechanism relies on dual “chemical cementation (product encapsulation/entanglement) - physical filling (unreacted FA pore-filling)” effects, achieving particle bonding and microstructural densification to enhance mechanical properties. Under comparable strength requirements, MOS-FA exhibits superior carbon emission performance, underscoring its environmental sustainability for loess stabilization.

为了解决生态脆弱的黄土高原的侵蚀问题，本研究开发了一种绿色替代波特兰水泥基固化剂：硫酸镁水泥（MOS）与工业废粉煤灰（FA）结合，符合绿色化学原理。物理试验结果表明，MOS-FA复合材料显著优化了黄土的孔隙度：对于mos - 15% FA样品，孔隙体积减小到0.233 mL/g（孔隙率为31.4%，大孔隙率为10.7%，中小孔隙率为28.8%），抗压强度从1.3 MPa提高到7.1 MPa。微观结构分析表明，水化产物（片状Mg(OH)2、絮状M-S-H/M-A-S-H/ C-S-H、针状5·1·7相）填充颗粒孔隙并形成连接，TG/DTG证实水化产物为硅酸盐水合物。固化机理依靠双重“化学胶结（产品封装/缠结）-物理填充（未反应FA孔隙填充）”效应，实现颗粒结合和微观结构致密化，提高力学性能。在同等强度要求下，MOS-FA表现出优异的碳排放性能，突出了其稳定黄土的环境可持续性。

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引用次数: 0

Comparison of hydro-pumped and green hydrogen as energy storage processes: A case study on Kefalonia Island, Greece 抽水蓄能和绿色蓄能的比较：以希腊凯法利尼亚岛为例

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-20 DOI: 10.1016/j.scp.2025.102216

A.-F. Papathanasiou, G. Pasaniotis, E. Baltas

The present research work investigates the performance of two large-scale energy storage technologies: hydro-pumped storage (HPS) and green hydrogen production, within a hybrid renewable energy system (HRES) developed for Kefalonia Island, Greece. Given the island's seasonal water and electricity shortages driven by summer demand and limited infrastructure, the goal is to identify which storage option better supports local autonomy. Two scenarios, differing only in storage method, were simulated using identical wind input and desalination setup. Performance was evaluated based on climate and demand data, focusing on water and electricity needs. Both scenarios achieved 99.9 % potable water coverage. The HPS system exhibited notably higher energy efficiency (67 %) compared to hydrogen (33 %), and produced slightly more desalinated water, reaching 18,157,791 m³ versus 17,986,544 m³ respectively. Electricity demand coverage reached 77.8 % with HPS and 76.0 % with hydrogen, while irrigation demand was met by 80.2 % and 79.4 %, respectively. Seasonal storage analysis revealed pronounced summer depletion in both cases due to high demand and low wind availability, with HPS recovering faster and maintaining higher storage levels owing to lower energy losses. The comparison underscores the need for storage strategies adapted to island-specific water and energy dynamics. HPS is more efficient for short-to-medium-term needs, while green hydrogen offers potential for long-duration storage and deeper decarbonization.

目前的研究工作调查了两种大规模储能技术的性能：在为希腊Kefalonia岛开发的混合可再生能源系统（HRES）内的抽水蓄能（HPS）和绿色制氢。考虑到夏季需求和有限的基础设施导致的岛上季节性水电短缺，目标是确定哪种存储选项更能支持地方自治。使用相同的风输入和海水淡化装置模拟了两种情况，仅在存储方法上有所不同。绩效评估基于气候和需求数据，重点关注水电需求。两种方案都实现了99.9%的饮用水覆盖率。HPS系统的能源效率（67%）明显高于氢系统（33%），并且产生的淡化水略多，分别达到18,157,791 m3和17,986,544 m3。HPS和氢气的电力需求覆盖率分别达到77.8%和76.0%，灌溉需求分别达到80.2%和79.4%。季节性存储分析显示，由于高需求和低风力可用性，两种情况下夏季都明显枯竭，HPS恢复得更快，并且由于能量损失更低而保持更高的存储水平。这种比较强调了需要适应岛屿特定的水和能源动态的储存策略。HPS更有效地满足中短期需求，而绿色氢提供了长期储存和深度脱碳的潜力。

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引用次数: 0

Enhancing the hydration activity of steel slag-Portland cement composite by BES sodium activator BES钠活化剂提高钢渣-硅酸盐水泥复合材料的水化活性

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-19 DOI: 10.1016/j.scp.2025.102213

Lei Chang , Suping Cui , Jianfeng Wang , Hui Liu , Binjie Zhou

The low hydration activity of steel slag (SS) limits its use in cement-based materials. The aim of this work was to explore the feasibility of N, N-bis(2-hydroxyethyl)-2-aminoethanesulfonic acid (BES) sodium as a novel activator in enhancing the hydration of SS-Portland cement (PC) (mass ratio of 3:7) composite. The compressive strength and hydration process of SS-PC composite and the working mechanism of BES sodium were systematically investigated. The results showed that at low dose (0.1 %), BES sodium significantly enhanced the 3–28 d compressive strengths by 2.1–4.6 MPa. This enhancement stemmed from the simultaneous acceleration of aluminates (C₃A and C₁₂A₇), ferrites (C₄AF and C₂F), and silicates (C₃S and β-C₂S) hydration, and which facilitated the formation of ettringite (AFt), hemicarboaluminate (Hc), and C–S–H gels. At high dose (0.5 %), BES sodium did not affect the 3 d compressive strength and significantly increased the 7 and 28 d compressive strengths by 4.7 and 4.2 MPa. This was because the excessive acceleration of aluminates inhibited early silicates hydration. This inhibition gradually disappeared from 7 to 28 d. The activation mechanism involved BES sodium accelerated the dissolution and hydration of minerals via complexing to Ca²⁺, Al³⁺ and Fe³⁺, and its stronger complexation for Al³⁺ and Fe³⁺ explained the preferential acceleration for aluminates/ferrites. Crucially, using 0.1 % BES sodium can effectively reduce 0.221–0.234 tons of CO₂/ton SS-PC under the premise of 28 d compressive strength more than 42.5 MPa. This highlighted the potential of BES sodium as an effective activator in improving SS utilization by enhancing SS hydration activity.

钢渣水化活性低，限制了其在水泥基材料中的应用。本文旨在探讨N， N-双（2-羟乙基）-2-氨基乙磺酸（BES）钠作为新型活化剂促进质量比为3:7的ss -硅酸盐水泥（PC）复合材料水化的可行性。系统研究了SS-PC复合材料的抗压强度和水化过程，以及BES钠的作用机理。结果表明：低剂量（0.1%）下，BES钠可显著提高3 ~ 28 d抗压强度2.1 ~ 4.6 MPa；这种增强是由于铝酸盐（C3A和C12A7）、铁氧体（C4AF和C2F）和硅酸盐（C3S和β-C2S）的水化同时加速，促进了钙矾石（AFt）、半碳铝酸盐（Hc）和C-S-H凝胶的形成。在高剂量（0.5%）下，BES钠对3 d抗压强度无影响，但可显著提高7和28 d抗压强度4.7和4.2 MPa。这是因为铝酸盐的过度加速抑制了早期硅酸盐的水化。从7 d到28 d，这种抑制作用逐渐消失。BES钠的活化机制是通过与Ca2+、Al3+和Fe3+的络合作用加速矿物的溶解和水化，其对Al3+和Fe3+的络合作用较强，解释了其对铝酸盐/铁氧体的优先加速作用。关键是，在28 d抗压强度大于42.5 MPa的前提下，使用0.1%的BES钠可有效减少0.221 ~ 0.234吨CO2/吨SS-PC。这突出了BES钠作为一种有效的活化剂通过提高SS水化活性来提高SS利用率的潜力。

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引用次数: 0

Green chemistry meets theoretical chemistry – comparison of 24 quantum chemical methods for calculating NMR shielding constants using the RGB model 绿色化学满足理论化学-使用RGB模型计算NMR屏蔽常数的24种量子化学方法的比较

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-19 DOI: 10.1016/j.scp.2025.102215

Paweł Mateusz Nowak , Dariusz Maciej Pisklak , Łukasz Szeleszczuk

The idea of green chemistry has already found many recipients, but not yet among computational chemists. Although theoretical methods indeed do not use chemical reagents and do not produce laboratory waste, due to the complexity of calculations they often require a lot of energy and can generate a significant carbon footprint. In our opinion, the basic question is not “Should we take into account the carbon footprint of computational methods in their assessment?”, but “How to do it properly?” In this work, we have attempted to address this issue by using an RGB model, a well-known tool used for assessing analytical chemistry methods, that has been adapted to the specifics of computational chemistry (RGB_in-silico). The model uses three primary parameters: the calculation error (red), the carbon footprint resulting from the energy consumption of the computer (green), and the computation time (blue). In phase I, acceptability thresholds are adopted. Methods that are unacceptable in at least one aspect are rejected. In phase II methods are comprehensively compared in terms of “whiteness”. The model was validated on 24 quantum chemical methods for calculating NMR shielding constants, differing in functionals and basis sets. The obtained results indicate a huge discrepancy between the methods, and therefore, the need to use a dedicated tool for selecting the optimal one in a rational way. The large values of the carbon footprint clearly indicate that some computational methods cannot be considered as “green in nature”. The RGB_in-silico model seems to be a simple and useful metric.

绿色化学的概念已经找到了许多接受者，但还没有在计算化学家中。虽然理论方法确实不使用化学试剂，也不产生实验室废物，但由于计算的复杂性，它们往往需要大量的能量，并可能产生显著的碳足迹。在我们看来，最基本的问题不是“我们是否应该在评估计算方法时考虑它们的碳足迹？”，而是“如何正确地做这件事？”在这项工作中，我们试图通过使用RGB模型来解决这个问题，RGB模型是一种用于评估分析化学方法的知名工具，已经适应了计算化学的具体情况（rgb_in - silicon）。该模型使用三个主要参数：计算误差（红色）、计算机能耗产生的碳足迹（绿色）和计算时间（蓝色）。在阶段1中，采用可接受阈值。至少在一个方面不可接受的方法将被拒绝。在第二阶段中，综合比较了各种方法的“白度”。该模型在24种计算核磁共振屏蔽常数的量子化学方法上进行了验证，这些方法在功能和基集上有所不同。得到的结果表明，方法之间存在巨大差异，因此，需要使用专用工具以合理的方式选择最优方法。碳足迹的大数值清楚地表明，一些计算方法不能被认为是“绿色的”。rgb_in - silicon模型似乎是一个简单而有用的度量。

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引用次数: 0

Pivotal role of support architecture in encapsulating heteropolyacids: Enhancing water tolerance and suppressing leaching for aqueous ethanol dehydration 支撑结构在包封杂多酸中的关键作用：增强水耐受性和抑制水乙醇脱水的浸出

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-18 DOI: 10.1016/j.scp.2025.102212

Artit Ausavasukhi , Kannika Noenkrathok , Natkamon Kongnok , Titiporn Wattanakul

Phosphotungstic acid (PTA) and silicotungstic acid (STA) encapsulated on a variety of porous materials (SBA-15, MCM-41, hierarchical zeolite ZSM-5 (h-ZSM-5) and hierarchical zeolite Beta (h-Beta)) were investigated for aqueous ethanol dehydration. Among the catalysts, the STA/SBA-15 consistently demonstrated the best catalytic activity, resulting in a high ethanol conversion and remarkable operating stability. On the other hand, the STA/h-Beta displayed considerably lower initial activity and greater deactivation. Thermal regeneration (300 °C) was quite effective in fully restoring the catalytic activity and selectivity that were acquired from the STA/SBA-15 (0.58 % decrease in ethanol conversion). However, the activity of STA/h-Beta was only partially recovered (15.09 % decrease in ethanol conversion). The leaching of active STA species during ethanol dehydration was the direct cause of the poor regeneration of the STA/h-Beta. The ICP analysis revealed a considerable drop in the tungsten content of the spent STA/h-Beta catalyst. This suggests that some STA was allowed to dissolve because it was not adequately contained in the hierarchical pore structure.

研究了磷钨酸（PTA）和硅钨酸（STA）在多种多孔材料（SBA-15、MCM-41、分级沸石ZSM-5 （h-ZSM-5）和分级沸石Beta (h-Beta)）上的包封对乙醇水脱水的影响。在催化剂中，STA/SBA-15始终表现出最好的催化活性，具有较高的乙醇转化率和良好的操作稳定性。另一方面，STA/h-Beta表现出相当低的初始活性和更大的失活。热再生（300°C）可以完全恢复STA/SBA-15的催化活性和选择性（乙醇转化率降低0.58%）。然而，STA/h-Beta活性仅部分恢复（乙醇转化率下降15.09%）。乙醇脱水过程中活性STA的浸出是STA/h-Beta再生能力差的直接原因。ICP分析显示，废STA/h-Beta催化剂的钨含量显著下降。这表明一些STA被允许溶解，因为它没有充分包含在分层孔隙结构中。

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引用次数: 0

Furfural-based phenolic resins for plywood panels: From basic concepts to upscale production 用于胶合板的糠醛基酚醛树脂：从基本概念到高档生产

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-17 DOI: 10.1016/j.scp.2025.102205

Electra Papadopoulou , Christina P. Pappa , Konstantina Karidi , Konstantinos S. Triantafyllidis

In this work, the use of furfural, a bio-based platform chemical, was investigated as a sustainable alternative to petrochemical formaldehyde in Phenol Formaldehyde (PF) resins, which are used in the manufacturing of wood-based products such as plywood. The catalytic condensation of phenol with furfural was studied at various temperatures (45–135^oC) to determine the reactivity of furfural towards formation of the respective dimers and oligomers. A pretreatment was applied to partially convert furfural to furfuryl alcohol which facilitated the condensation of phenol with furfural, at temperatures >90^oC. PF-Furfural (PFFu) resins were prepared at semi-pilot scale (2–3 Kg) following typical industrial protocols aiming at the gradual replacement (20–80 wt%) of formaldehyde. The properties of the PFFu resins were characterized by various methods (solids, pH, viscosity etc.) and ¹³C NMR analysis. The PFFu resins with up to 60 wt% replacement of formaldehyde by furfural exhibited typical properties for such PF-type resins; however, viscosity and gel time were gradually decreased and increased, respectively, indicating the relatively reduced reactivity of furfural at the applied synthesis conditions (i.e. 90-100^oC) compared to formaldehyde. Plywood panels prepared with PFFu resins, demonstrated enhanced mechanical performance compared to the reference PF resin — such as improved shear strength (>1.5 N/mm²) and wood failure (≥85 %) thereby meeting the requirements of the European standard EN314–2:1993. Furthermore, all panels prepared with furfural-containing resins exhibited significantly lower free formaldehyde emission (0.01–0.18 mg/m²h) compared to the reference panels (0.20 mg/m²h). The results highlight the possibility of formaldehyde replacement by furfural in the production of sustainable plywood products.

在这项工作中，研究了糠醛（一种生物基平台化学品）作为酚醛树脂（PF）中石化甲醛的可持续替代品的使用，酚醛树脂用于制造木材基产品，如胶合板。研究了不同温度（45 - 135℃）下苯酚与糠醛的催化缩合反应，以确定糠醛对二聚物和低聚物的反应性。在温度为90℃的条件下，将糠醛部分转化为糠醇，促进苯酚与糠醛的缩合反应。pf -糠醛（PFFu）树脂在半中试规模（2-3公斤）下按照典型的工业方案制备，旨在逐步替代甲醛（20-80 wt%）。采用固体、pH、粘度等方法对PFFu树脂的性能进行了表征，并用13C核磁共振分析对其进行了表征。糠醛替代甲醛达60%的PFFu树脂表现出此类pf型树脂的典型性能；但粘度和凝胶时间分别逐渐降低和增加，表明在应用合成条件下（即90-100℃），糠醛的反应性相对于甲醛降低。用PFFu树脂制备的胶合板，与参考的PF树脂相比，表现出增强的机械性能-例如改善的抗剪强度（>1.5 N/mm2）和木材破坏（≥85%），从而满足欧洲标准EN314-2:1993的要求。此外，与参考面板（0.20 mg/m2h）相比，所有用含糠醛树脂制备的面板的游离甲醛释放量（0.01-0.18 mg/m2h）均显著降低。研究结果强调了用糠醛替代甲醛生产可持续胶合板产品的可能性。

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引用次数: 0

Zero waste realization method of rice husk: Silica extraction and methylene blue adsorption 稻壳零废弃物的实现方法：二氧化硅萃取-亚甲基蓝吸附

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-14 DOI: 10.1016/j.scp.2025.102211

Ye-Ji Lee , Jeong-Min Lee , Jung-Won Park , Jim J. Wang , Meng Wang , Dong-Cheol Seo , Jong-Hwan Park

This study determined the optimal conditions for extracting Si from rice husk (RH) for efficient resource utilization of RH and evaluated the adsorption characteristics of methylene blue (MB) by Si-extracted RH (Si-RH). The optimal conditions for extracting silica from RH were mixing 0.6 M NaOH (1:10 ratio) with RH (>2 mm) and reacting at 70 °C for 2 h. The maximum adsorption amount of MB by Si-RH with expanded surface area and reinforced cellulose-hemicellulose-lignin matrix was 99.01 mg/g, which was three times higher than that of RH (34.36 mg/g), and better fit the Langmuir isotherm and Pseudo-second order models. It was found that the adsorption of MB by Si-RH was greatly affected by environmental changes such as reaction time, pH, dosage, and reaction temperature. The surface properties by SEM-EDS and FTIR and the adsorption model equation showed that the adsorption of MB by Si-RH was dominated by complex mechanisms rather than a single mechanism, and these greatly influenced the initial adsorption-desorption process of MB by Si-RH. In continuous adsorption-desorption experiments, Si-RH showed excellent adsorption efficiency for MB. In conclusion, the extraction of silica from RH and utilization of the residue as a dye adsorbent proposed in this study is considered to be the optimal method for realizing zero waste of RH.

本研究确定了从稻壳（RH）中提取Si的最佳工艺条件，以实现RH的高效资源化利用，并对Si萃取的RH （Si-RH）对亚甲基蓝（MB）的吸附特性进行了评价。从RH中提取二氧化硅的最佳工艺条件为：0.6 M NaOH（1:10）与RH （>2 mm）混合，在70℃下反应2 h。扩大表面积、增强纤维素-半纤维素-木质素基质的Si-RH对MB的最大吸附量为99.01 mg/g，是RH （34.36 mg/g）的3倍，更符合Langmuir等温线和拟二级模型。结果表明，Si-RH对MB的吸附受反应时间、pH、投加量、反应温度等环境因素的影响较大。SEM-EDS和FTIR的表面性质以及吸附模型方程表明，Si-RH对MB的吸附是由复杂的机理主导的，而不是单一的机理，这些都对Si-RH对MB的初始吸附-解吸过程产生了很大的影响。在连续的吸附-解吸实验中，Si-RH对MB表现出了优异的吸附效率。综上所述，本研究提出的从RH中提取二氧化硅并将其残渣用作染料吸附剂是实现RH零浪费的最佳方法。

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引用次数: 0

Fabrication of a cellulose paper based rotating paper disc as sustainable extraction device for anesthetic drug analysis in postmortem blood 以纤维素纸为基础的可旋转纸盘的制造，可用于死后血液中麻醉药物分析的可持续提取装置

IF 5.8 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy

Pub Date : 2025-09-13 DOI: 10.1016/j.scp.2025.102206

Rajeev Jain , Atul Bajaj , Sarah Alharthi , Mohammed Idris , Lateefa A. Al-Khateeb

In the present work, a rotating paper disc (RPD) device is fabricated and applied for effective, facile, and high-throughput extraction of four anesthetic drugs (prilocaine, lidocaine, bupivacaine, and ropivacaine) from forensic postmortem blood. The RPD utilizes a low-cost, natural, and biodegradable cellulose-based sorbent that is impregnated with octanol to enhance amphiphilic interactions for effective drug extraction. Device fabrication involves placing a magnetic bar between the layers of octanol-supported cellulose, which allows direct immersion in diluted blood samples and its rotation in the magnetic field. The important parameters, such as pH, ionic strength, extraction/desorption rate, and time, were optimized systematically. Adsorption was optimized at 400 rpm for 30 min and then rapid back-extraction into 2 mL of ethyl acetate. The approach showed good linearity (0.1–5 μg mL⁻¹), good extraction efficiency (92–112 % recovery), low LOQs (0.05–0.09 μg mL⁻¹), and excellent intra-day/inter-day precision (3.5–13.4 %). The disposable RPD device eliminates carry-over between samples and supports high sample throughput (15 samples/h) at a low cost (∼$0.3/unit). The BAGI practicality score (75) and ComplexMoGAPI greenness score (80) validate the method's compliance with green and white analytical chemistry. Applied to forensic toxicology casework, the procedure successfully determined an anesthetic drug in actual postmortem blood samples, illustrating its potential for regular forensic and clinical toxicology uses. Considering its sustainability, low cost, and excellent sensitivity, the RPD-GC-MS strategy is an innovative approach in sample preparation.

本研究制作了一种旋转纸盘（RPD）装置，用于从法医死后血液中高效、简便、高通量地提取四种麻醉药物（丙罗卡因、利多卡因、布比卡因和罗哌卡因）。RPD采用低成本、天然、可生物降解的纤维素基吸附剂，浸透辛醇，增强两亲性相互作用，有效提取药物。该装置的制造过程包括在辛醇支撑的纤维素层之间放置一个磁棒，它可以直接浸入稀释的血液样本中，并在磁场中旋转。对pH、离子强度、萃取/解吸速率、时间等重要参数进行了系统优化。最佳吸附条件为：400 rpm，吸附30 min，然后快速反萃取至2ml乙酸乙酯中。该方法线性良好（0.1 ~ 5 μg mL−1），提取效率高（回收率92 ~ 112%），检出限低（0.05 ~ 0.09 μg mL−1），日内/日间精密度高（3.5 ~ 13.4%）。一次性RPD装置消除了样品之间的携带，并以低成本（约0.3美元/单位）支持高样品吞吐量（15个样品/小时）。BAGI实用性得分（75）和ComplexMoGAPI绿色得分（80）验证了该方法符合绿色和白色分析化学。应用于法医毒理学案例工作，该程序成功地在实际的死后血液样本中确定了麻醉药物，说明了其在法医和临床毒理学常规应用中的潜力。考虑到其可持续性、低成本和优异的灵敏度，RPD-GC-MS策略是一种创新的样品制备方法。

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引用次数: 0