Pub Date : 2023-07-03DOI: 10.1080/1539445X.2023.2232777
Harun A. R. Pramanik, Bandashisha Kharpan, B. Bhattacharya, C. Bhattacharjee, P. Paul, U. Sarkar, S. K. Prasad, D. S. S. Rao
ABSTRACT A new photoluminescent disc-like copper (II) metallomesogen of the type [CuL2] {H2L = 2,4-bis((E)-((4-(hexadecyloxy)phenyl)imino)methyl)phenol} have been synthesized. The compounds were characterized by elemental analyses, Fourier transform infrared spectroscopy (FTIR), 1H, 13C nuclear magnetic resonance (NMR), ultraviolet – visible spectroscopy (UV – Vis), thermogravimetric analysis (TGA) and high-resolution mass spectrometry. Mesomorphic behavior of the compounds was probed with the help of polarizing optical microscopy (POM) and differential scanning calorimetry (DSC). The organization of the molecules in the mesophase was investigated by X-ray diffraction techniques. The ligand is non-mesogenic but the copper complex exhibited thermally stable columnar mesophases at about 86°C. The copper complex is a blue-light emitter both in solution and in the solid state. The Density Functional Theory (DFT) study was carried out using 6–31 G (d, p) basis set with unrestricted B3LYP level to obtain a stable, optimized structure, which revealed a distorted square-planar geometry for the copper complexes.
合成了一种新的光致发光圆盘状铜(II)金属原[CuL2] {H2L = 2,4-双((E)-((4-(十六基氧基)苯基)亚氨基)甲基)苯酚}。通过元素分析、傅里叶红外光谱(FTIR)、1H、13C核磁共振(NMR)、紫外-可见光谱(UV - Vis)、热重分析(TGA)和高分辨率质谱对化合物进行了表征。利用偏光显微镜(POM)和差示扫描量热仪(DSC)研究了化合物的亚晶行为。用x射线衍射技术研究了中间相的分子结构。配体是非介生的，但铜配合物在约86℃时表现出热稳定的柱状介相。铜配合物在溶液和固体状态下都是蓝光发射器。利用密度泛函理论(DFT)研究了6-31 G (d, p)基集和不受限制的B3LYP水平，得到了稳定的优化结构，揭示了铜配合物的扭曲的方平面几何结构。
{"title":"Mononuclear photoluminescent salicylaldimato copper(II) complex: synthesis, characterization, mesomorphic investigation and DFT study","authors":"Harun A. R. Pramanik, Bandashisha Kharpan, B. Bhattacharya, C. Bhattacharjee, P. Paul, U. Sarkar, S. K. Prasad, D. S. S. Rao","doi":"10.1080/1539445X.2023.2232777","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2232777","url":null,"abstract":"ABSTRACT A new photoluminescent disc-like copper (II) metallomesogen of the type [CuL2] {H2L = 2,4-bis((E)-((4-(hexadecyloxy)phenyl)imino)methyl)phenol} have been synthesized. The compounds were characterized by elemental analyses, Fourier transform infrared spectroscopy (FTIR), 1H, 13C nuclear magnetic resonance (NMR), ultraviolet – visible spectroscopy (UV – Vis), thermogravimetric analysis (TGA) and high-resolution mass spectrometry. Mesomorphic behavior of the compounds was probed with the help of polarizing optical microscopy (POM) and differential scanning calorimetry (DSC). The organization of the molecules in the mesophase was investigated by X-ray diffraction techniques. The ligand is non-mesogenic but the copper complex exhibited thermally stable columnar mesophases at about 86°C. The copper complex is a blue-light emitter both in solution and in the solid state. The Density Functional Theory (DFT) study was carried out using 6–31 G (d, p) basis set with unrestricted B3LYP level to obtain a stable, optimized structure, which revealed a distorted square-planar geometry for the copper complexes.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"280 - 292"},"PeriodicalIF":1.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59884731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-22DOI: 10.1080/1539445X.2023.2226127
F. Ito, Hidetaka Yamada
ABSTRACT A high-performance CO2 separation membrane was fabricated using a composite polymer composed of a crosslinked acrylic acid polymer sodium salt, sodium polyacrylate, polyvinyl alcohol, and cesium carbonate. Evaluation tests were conducted by varying the relative humidity (RH), temperature, total pressure (Ptotal), and CO2 partial pressure (PCO2) to determine optimal parameters for enhanced performance in selective CO2 permeation over He. The membrane shows a high separation performance and durability at 50% RH and 85°C, where the CO2/He selectivity exceeds 550 under conditions of Ptotal:0.1 MPa and PCO2:0.08 MPa. Furthermore, the operational stability of the membrane was evaluated at 85°C, 50% RH, Ptotal:0.7 MPa, and PCO2:0.56 MPa. The as-fabricated membrane was stable for 300 h of continuous operation in the separation performance evaluation test. The findings of this study suggest that the developed membranes can be applied for CO2 separation from gas mixtures such as CO2/H2 with high efficiency and stability.
{"title":"Selective CO2 permeation properties of a membrane composed of a three-component polymer blend and cesium carbonate","authors":"F. Ito, Hidetaka Yamada","doi":"10.1080/1539445X.2023.2226127","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2226127","url":null,"abstract":"ABSTRACT A high-performance CO2 separation membrane was fabricated using a composite polymer composed of a crosslinked acrylic acid polymer sodium salt, sodium polyacrylate, polyvinyl alcohol, and cesium carbonate. Evaluation tests were conducted by varying the relative humidity (RH), temperature, total pressure (Ptotal), and CO2 partial pressure (PCO2) to determine optimal parameters for enhanced performance in selective CO2 permeation over He. The membrane shows a high separation performance and durability at 50% RH and 85°C, where the CO2/He selectivity exceeds 550 under conditions of Ptotal:0.1 MPa and PCO2:0.08 MPa. Furthermore, the operational stability of the membrane was evaluated at 85°C, 50% RH, Ptotal:0.7 MPa, and PCO2:0.56 MPa. The as-fabricated membrane was stable for 300 h of continuous operation in the separation performance evaluation test. The findings of this study suggest that the developed membranes can be applied for CO2 separation from gas mixtures such as CO2/H2 with high efficiency and stability.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"261 - 270"},"PeriodicalIF":1.2,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43158215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-21DOI: 10.1080/1539445X.2023.2222388
Kyra Danielle C. Magdato, Monissa C. Paderes
ABSTRACT Self-assembled systems based on low-molecular-weight gelators (LMWGs) and micelle-forming surfactants are stabilized by non-covalent and non-interfering interactions. The simultaneous self-assembly of LMWGs and surfactants in a solution could lead to the formation of fibrillar networks with encapsulated surfactant micelles. In this study, the gelation properties of amino-acid-derived low-molecular-weight bis-urea compounds in water, various organic solvents, and surfactant solutions, including anionic surfactants sodium dodecyl sulfate and dodecylbenzene sulfonic acid, cationic surfactant cetrimonium bromide, and nonionic surfactants polysorbate 80 and octyl-β-d-glucopyranoside, were investigated. In the presence of surfactants, the nature of the linker of the bis-urea compounds influences the aggregation between gelator molecules. Compounds with cyclic and aromatic linkers effectively form gels at surfactant concentrations above a critical micelle concentration (CMC). The different fiber morphologies observed for surfactant gels based on imaging analysis suggest that the structure of the bis-urea compounds influences self-assembly. Rheological measurements revealed the solid-like nature of the gels and their high thermal stability. The viscoelastic nature of the surfactant gels offers potential use in various commercial applications, including home care products.
{"title":"Gelation properties of amino-acid-based bis-urea compounds in organic solvents and in the presence of surfactants","authors":"Kyra Danielle C. Magdato, Monissa C. Paderes","doi":"10.1080/1539445X.2023.2222388","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2222388","url":null,"abstract":"ABSTRACT Self-assembled systems based on low-molecular-weight gelators (LMWGs) and micelle-forming surfactants are stabilized by non-covalent and non-interfering interactions. The simultaneous self-assembly of LMWGs and surfactants in a solution could lead to the formation of fibrillar networks with encapsulated surfactant micelles. In this study, the gelation properties of amino-acid-derived low-molecular-weight bis-urea compounds in water, various organic solvents, and surfactant solutions, including anionic surfactants sodium dodecyl sulfate and dodecylbenzene sulfonic acid, cationic surfactant cetrimonium bromide, and nonionic surfactants polysorbate 80 and octyl-β-d-glucopyranoside, were investigated. In the presence of surfactants, the nature of the linker of the bis-urea compounds influences the aggregation between gelator molecules. Compounds with cyclic and aromatic linkers effectively form gels at surfactant concentrations above a critical micelle concentration (CMC). The different fiber morphologies observed for surfactant gels based on imaging analysis suggest that the structure of the bis-urea compounds influences self-assembly. Rheological measurements revealed the solid-like nature of the gels and their high thermal stability. The viscoelastic nature of the surfactant gels offers potential use in various commercial applications, including home care products.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"251 - 260"},"PeriodicalIF":1.2,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45705941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.1080/1539445X.2023.2206087
Manisha Jhajhria, S. Sahoo, T. Biswas, S. Thakur
ABSTRACT Spontaneous symmetry breaking has been shown to be the genesis of self-assembly in a mixture of spherically symmetric chemically active and passive colloids, forming dense clusters. Here, we study the kinetics of such self-assembly, driven by the phoretic motion of passive colloids following the chemical gradient generated by the active seeds. A non-monotonic effect of activity on aggregation is the key observation in this work. We rationalize such non-monotonicity in the clustering by the hybrid coarse-grained simulations. The average cluster population and the variation of their size as a function of time, the stability of clusters, and their dynamics are the key quantifications that help us comprehend the aggregation.
{"title":"Activity induced non-monotonic aggregation in a mixture of chemically active and passive particles","authors":"Manisha Jhajhria, S. Sahoo, T. Biswas, S. Thakur","doi":"10.1080/1539445X.2023.2206087","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2206087","url":null,"abstract":"ABSTRACT Spontaneous symmetry breaking has been shown to be the genesis of self-assembly in a mixture of spherically symmetric chemically active and passive colloids, forming dense clusters. Here, we study the kinetics of such self-assembly, driven by the phoretic motion of passive colloids following the chemical gradient generated by the active seeds. A non-monotonic effect of activity on aggregation is the key observation in this work. We rationalize such non-monotonicity in the clustering by the hybrid coarse-grained simulations. The average cluster population and the variation of their size as a function of time, the stability of clusters, and their dynamics are the key quantifications that help us comprehend the aggregation.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"237 - 250"},"PeriodicalIF":1.2,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47728577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-23DOI: 10.1080/1539445X.2023.2203688
P. Kantha, Sornchat Phiw-on, O. Pinyakong, S. Teepoo, Atipong Bootchanont, Naris Barnthip
ABSTRACT Gelatin hydrogels containing the Chromolaena odorata (Siam Weed) crude extract were fabricated to study the morphology, the percentage of swelling, the total flavonoids released under a system without and with the external voltage stimulation, and the antibacterial properties. The percentage of pore area per cross-sectional area of the hydrogel was 23.56%. The hydrogels showed the extraordinarily high swelling percentage of 1,087.32 ± 16.16%. The total released flavonoids increased over time for both the systems without and with the external voltage stimulation. The total released flavonoid content from the systems with the external voltage stimulation was in larger quantities and more rapidly release comparing to the system in the absence of external voltage stimulation. The equivalent amount of the total released flavonoid tended to increase with the stimulating voltage of 0–0.3 V, but decreased when the excitation voltage was more than 0.3 V. Preferred amount of the total flavonoids released from hydrogels could be partly controlled by specific voltage stimulation. The fabricated hydrogel exhibits novel and great initial properties for wound healing materials and wound care application not only due to its extremely water absorption characteristic, but also perfectly in Gram-positive bacteria growth inhibition, which is ideal for the treatment of certain wounds with infection.
{"title":"Preparation of Chromolaena odorata (Siam weed) loaded hydrogels and the effect of electrical potentials on the total flavonoids releasing behavior for wound healing application","authors":"P. Kantha, Sornchat Phiw-on, O. Pinyakong, S. Teepoo, Atipong Bootchanont, Naris Barnthip","doi":"10.1080/1539445X.2023.2203688","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2203688","url":null,"abstract":"ABSTRACT Gelatin hydrogels containing the Chromolaena odorata (Siam Weed) crude extract were fabricated to study the morphology, the percentage of swelling, the total flavonoids released under a system without and with the external voltage stimulation, and the antibacterial properties. The percentage of pore area per cross-sectional area of the hydrogel was 23.56%. The hydrogels showed the extraordinarily high swelling percentage of 1,087.32 ± 16.16%. The total released flavonoids increased over time for both the systems without and with the external voltage stimulation. The total released flavonoid content from the systems with the external voltage stimulation was in larger quantities and more rapidly release comparing to the system in the absence of external voltage stimulation. The equivalent amount of the total released flavonoid tended to increase with the stimulating voltage of 0–0.3 V, but decreased when the excitation voltage was more than 0.3 V. Preferred amount of the total flavonoids released from hydrogels could be partly controlled by specific voltage stimulation. The fabricated hydrogel exhibits novel and great initial properties for wound healing materials and wound care application not only due to its extremely water absorption characteristic, but also perfectly in Gram-positive bacteria growth inhibition, which is ideal for the treatment of certain wounds with infection.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"219 - 228"},"PeriodicalIF":1.2,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59885145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-03DOI: 10.1080/1539445X.2023.2196977
Moumita Tewary, Tarapada Roy
ABSTRACT Intelligent electroactive polymer-based dielectric elastomer actuators (DEAs) are capable of geometrical disorientation. These actuators are susceptible to electro-thermo-mechanical instability due to their ability to be electrically powered at various stresses and temperatures. This proposed work provides mathematical derivations for the study of instability in coupled electro-thermo-mechanical anisotropic bimorph convex DEAs. The equilibrium equations are formulated assuming the taper ratio because of the convex structure and the ply angles due to anisotropy. MATLAB is employed to numerically solve the complicated equations for critical stretch, nominal electric field, and entropy under a variety of mechanical, electrical, and thermal loads. The observations indicate that under conditions of , and , an increase in nominal stress from to leads to a corresponding increase in the peak point of the nominal electric field, specifically from to for axial stretch values of 2.107 and 2.159, respectively. When the nominal electric field is reported against nominal electric displacement, it enhances with the rise in temperature and reduces with the hike in nominal stress and taper ratio. When the fibers are arranged parallel to the axial stretch direction then the failure point of stretch is least, compared to that oriented in a perpendicular direction. The present study demonstrates that elevated temperature and nominal stress result in an increase in entropy, leading to a corresponding increase in system disorder. Furthermore, the perpendicular alignment of fibers with respect to axial stretch is found to decrease the degree of system randomness.
{"title":"Electro-thermo-mechanical instability study of fiber-reinforced bimorph convex dielectric elastomer","authors":"Moumita Tewary, Tarapada Roy","doi":"10.1080/1539445X.2023.2196977","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2196977","url":null,"abstract":"ABSTRACT Intelligent electroactive polymer-based dielectric elastomer actuators (DEAs) are capable of geometrical disorientation. These actuators are susceptible to electro-thermo-mechanical instability due to their ability to be electrically powered at various stresses and temperatures. This proposed work provides mathematical derivations for the study of instability in coupled electro-thermo-mechanical anisotropic bimorph convex DEAs. The equilibrium equations are formulated assuming the taper ratio because of the convex structure and the ply angles due to anisotropy. MATLAB is employed to numerically solve the complicated equations for critical stretch, nominal electric field, and entropy under a variety of mechanical, electrical, and thermal loads. The observations indicate that under conditions of , and , an increase in nominal stress from to leads to a corresponding increase in the peak point of the nominal electric field, specifically from to for axial stretch values of 2.107 and 2.159, respectively. When the nominal electric field is reported against nominal electric displacement, it enhances with the rise in temperature and reduces with the hike in nominal stress and taper ratio. When the fibers are arranged parallel to the axial stretch direction then the failure point of stretch is least, compared to that oriented in a perpendicular direction. The present study demonstrates that elevated temperature and nominal stress result in an increase in entropy, leading to a corresponding increase in system disorder. Furthermore, the perpendicular alignment of fibers with respect to axial stretch is found to decrease the degree of system randomness.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"191 - 205"},"PeriodicalIF":1.2,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49394564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-03DOI: 10.1080/1539445X.2023.2199419
N. Naidek, N. Khalil, C. Almeida
ABSTRACT Besides being known by food and perfume industries, vanillin has also important pharmacological properties such as anti-inflammatory and antibacterial activities. The use of magnetic nanoparticles as carriers for a vanillin delivery system is a way to explore its benefits in human beings. In this paper, poly(lactic-co-glycolic acid) (PLGA) nanoparticles stabilized by poly(vinyl alcohol) (PVA) and containing magnetic CoFe2O4 and vanillin have been prepared using a double emulsion-solvent evaporation method. The morphology, particle size, structure, and surface properties of the nanoparticles were investigated by transmission electron microscopy, zeta-potential measurements, X-ray diffractometry, Fourier transform infrared spectroscopy, magnetic hysteresis loops, and thermogravimetric analysis. The spherical nanoparticles presented negative charge, with zeta-potential values ranging from −9.15 to −5.64 mV, high thermal stability, superparamagnetic properties, and excellent encapsulation of the vanillin (around 80%). Accordingly, such PLGA/PVA nanoparticles encapsulating vanillin and CoFe2O4 exhibited the desired features to suggest their potential use as drug delivery systems. Highlights PLGA/PVA nanoparticles with CoFe2O4 were synthesized for the targeted delivery of vanillin. The spherical nanoparticles presented negative zeta-potential ranging from −9.15 to −5.64 mV. Encapsulation promoted an increased release rate of vanillin. Analytical validation was used for vanillin quantification.
{"title":"Poly-(lactic-co-glycolic acid) /poly-(vinyl alcohol) and cobalt ferrite magnetic nanoparticles as vanillin carriers","authors":"N. Naidek, N. Khalil, C. Almeida","doi":"10.1080/1539445X.2023.2199419","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2199419","url":null,"abstract":"ABSTRACT Besides being known by food and perfume industries, vanillin has also important pharmacological properties such as anti-inflammatory and antibacterial activities. The use of magnetic nanoparticles as carriers for a vanillin delivery system is a way to explore its benefits in human beings. In this paper, poly(lactic-co-glycolic acid) (PLGA) nanoparticles stabilized by poly(vinyl alcohol) (PVA) and containing magnetic CoFe2O4 and vanillin have been prepared using a double emulsion-solvent evaporation method. The morphology, particle size, structure, and surface properties of the nanoparticles were investigated by transmission electron microscopy, zeta-potential measurements, X-ray diffractometry, Fourier transform infrared spectroscopy, magnetic hysteresis loops, and thermogravimetric analysis. The spherical nanoparticles presented negative charge, with zeta-potential values ranging from −9.15 to −5.64 mV, high thermal stability, superparamagnetic properties, and excellent encapsulation of the vanillin (around 80%). Accordingly, such PLGA/PVA nanoparticles encapsulating vanillin and CoFe2O4 exhibited the desired features to suggest their potential use as drug delivery systems. Highlights PLGA/PVA nanoparticles with CoFe2O4 were synthesized for the targeted delivery of vanillin. The spherical nanoparticles presented negative zeta-potential ranging from −9.15 to −5.64 mV. Encapsulation promoted an increased release rate of vanillin. Analytical validation was used for vanillin quantification.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"206 - 217"},"PeriodicalIF":1.2,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41638966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.1080/1539445X.2023.2179069
Sara Alizadeh Majd, M. Moghimi Zand, R. Javidi, M. Rahimian
ABSTRACT Droplet-based microfluidics has received much attention in biofabrication due to its compatibility with 3D printers that use cell-laden bioinks. In order to tailor the printing resolution, droplet generation under a DC electric field in a flow-focusing device is explored numerically. The major purpose of simulations is to investigate how geometry affects droplet production and electric field intensity. The effects of the orifice’s length, injection angle, and shape are discussed regarding the electric capillary number . Based on the retardation effect, the necking stage of droplet formation changes to expansion, and the frequency of droplet formation declines when the capillary number rises. For a particular value of the applied electric potential, orifice elongation reduces the induced electric field within the orifice. By adjusting the angle of side flow, smaller droplets can be formed, and the linear decrease in droplet size is provided across a wider range. The electric field in the orifice was amplified by 64% by creating a wedge-shaped orifice. In other words, when the notch angle was sharpened, the electric force increased, and the droplet diameter reduced. Since the frequency of droplet production varied only slightly between different notch angles, it could be preferable to generate smaller droplets without significantly altering the frequency of droplet formation.
{"title":"Numerical investigation of electrohydrodynamic effect for size-tunable droplet formation in a flow-focusing microfluidic device","authors":"Sara Alizadeh Majd, M. Moghimi Zand, R. Javidi, M. Rahimian","doi":"10.1080/1539445X.2023.2179069","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2179069","url":null,"abstract":"ABSTRACT Droplet-based microfluidics has received much attention in biofabrication due to its compatibility with 3D printers that use cell-laden bioinks. In order to tailor the printing resolution, droplet generation under a DC electric field in a flow-focusing device is explored numerically. The major purpose of simulations is to investigate how geometry affects droplet production and electric field intensity. The effects of the orifice’s length, injection angle, and shape are discussed regarding the electric capillary number . Based on the retardation effect, the necking stage of droplet formation changes to expansion, and the frequency of droplet formation declines when the capillary number rises. For a particular value of the applied electric potential, orifice elongation reduces the induced electric field within the orifice. By adjusting the angle of side flow, smaller droplets can be formed, and the linear decrease in droplet size is provided across a wider range. The electric field in the orifice was amplified by 64% by creating a wedge-shaped orifice. In other words, when the notch angle was sharpened, the electric force increased, and the droplet diameter reduced. Since the frequency of droplet production varied only slightly between different notch angles, it could be preferable to generate smaller droplets without significantly altering the frequency of droplet formation.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"174 - 190"},"PeriodicalIF":1.2,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48968122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-14DOI: 10.1080/1539445X.2023.2172042
Ana Paula Buratto, B. H. Fontoura, S. Carpes, C. Almeida
ABSTRACT The objective of this research was to produce, characterize and evaluate biological activities of magnetic-polymeric nanoparticles loaded with resveratrol. Magnetic nanoparticles of cobalt ferrite (CoFe2O4), polymeric nanoparticles of chitosan (CS) and polyethylene glycol (PEG), and polymeric-magnetic nanoparticles containing resveratrol (RSV) were developed. An analytical method using UV-VIS spectroscopy was developed and validated for the determination of RSV in the nanoparticles. The samples were analyzed by dynamic light scattering (DLS) for size, polydispersity index (PDI) and zeta potential. The encapsulation efficiency was determined by an indirect method. Antioxidants (ABTS and DPPH) and antibacterial (MIC and CBM) activities were evaluated. The average size of the nanoparticles varied between 184.6 and 276.5 nm. The magnetic-polymeric nanoparticles showed high encapsulation efficiency (EE) (98.75%) with a slow and prolonged release rate of 33.49% in 120 h. Furthermore, three months of storage showed less than 10% of RSV degradation. Its antioxidant activity (AA) was 170.55 mmol TE g−1 (by the ABTS method) and 130.60 mmol TE g−1 (by the DPPH method). The resveratrol-loaded magnetic-polymeric nanoparticles inhibited the growth of four tested bacteria. Their MIC values were less than 52.36 µg mL−1, and the CBM values of the nanoparticles >52.36 µg mL−1. HIGHLIGHTS Cobalt ferrite NPs coated with chitosan and polyethylene glycol were synthesized for the targeted delivery of resveratrol. CoFe2O4 NPs coated with CS/PEG loaded with RSV showed average size of 234.40 nm. Resveratrol was encapsulated (>95%) onto CoFe2O4 NPs coated with chitosan/PEG. RSV-loaded nanoparticles were effective as a scavenger of ABTS and DPPH radicals, suggesting applications in processes involving oxidative stress. RSV-loaded magnetic-polymeric NPs showed antibacterial activity against four Gram-negative and Gram-positive bacteria.
摘要:本研究的目的是制备、表征和评价负载白藜芦醇的磁性聚合物纳米颗粒的生物活性。制备了钴铁氧体磁性纳米粒子(CoFe2O4)、壳聚糖(CS)和聚乙二醇(PEG)的聚合纳米粒子以及含白藜芦醇(RSV)的聚合磁性纳米粒子。建立并验证了紫外可见光谱法测定纳米颗粒中RSV的分析方法。采用动态光散射(DLS)对样品的尺寸、多分散性指数(PDI)和zeta电位进行了分析。采用间接法测定包封效率。测定抗氧化活性(ABTS和DPPH)和抗菌活性(MIC和CBM)。纳米颗粒的平均尺寸在184.6 ~ 276.5 nm之间。磁性高分子纳米颗粒的包封效率(EE)高达98.75%，120 h缓释率为33.49%，3个月对RSV的降解率低于10%。其抗氧化活性(AA)分别为170.55 mmol TE g−1 (ABTS法)和130.60 mmol TE g−1 (DPPH法)。负载白藜芦醇的磁性聚合物纳米颗粒抑制了四种被测细菌的生长。纳米颗粒的MIC值均小于52.36µg mL−1,CBM值均小于52.36µg mL−1。制备了壳聚糖和聚乙二醇包被的钴铁氧体NPs，用于白藜芦醇的靶向递送。CS/PEG包覆的CoFe2O4 NPs平均粒径为234.40 nm。将白藜芦醇包被(>95%)在壳聚糖/聚乙二醇包被的CoFe2O4 NPs上。负载rsv的纳米颗粒作为ABTS和DPPH自由基的有效清除剂，提示在氧化应激过程中的应用。负载rsv的磁性聚合物NPs对4种革兰氏阴性菌和革兰氏阳性菌均有抗菌活性。
{"title":"Preparation and characterization of chitosan/polyethylene glycol and cobalt ferrite magnetic-polymeric nanoparticles as resveratrol carriers: preparation, analytical methodology validation and in vitro applicability","authors":"Ana Paula Buratto, B. H. Fontoura, S. Carpes, C. Almeida","doi":"10.1080/1539445X.2023.2172042","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2172042","url":null,"abstract":"ABSTRACT The objective of this research was to produce, characterize and evaluate biological activities of magnetic-polymeric nanoparticles loaded with resveratrol. Magnetic nanoparticles of cobalt ferrite (CoFe2O4), polymeric nanoparticles of chitosan (CS) and polyethylene glycol (PEG), and polymeric-magnetic nanoparticles containing resveratrol (RSV) were developed. An analytical method using UV-VIS spectroscopy was developed and validated for the determination of RSV in the nanoparticles. The samples were analyzed by dynamic light scattering (DLS) for size, polydispersity index (PDI) and zeta potential. The encapsulation efficiency was determined by an indirect method. Antioxidants (ABTS and DPPH) and antibacterial (MIC and CBM) activities were evaluated. The average size of the nanoparticles varied between 184.6 and 276.5 nm. The magnetic-polymeric nanoparticles showed high encapsulation efficiency (EE) (98.75%) with a slow and prolonged release rate of 33.49% in 120 h. Furthermore, three months of storage showed less than 10% of RSV degradation. Its antioxidant activity (AA) was 170.55 mmol TE g−1 (by the ABTS method) and 130.60 mmol TE g−1 (by the DPPH method). The resveratrol-loaded magnetic-polymeric nanoparticles inhibited the growth of four tested bacteria. Their MIC values were less than 52.36 µg mL−1, and the CBM values of the nanoparticles >52.36 µg mL−1. HIGHLIGHTS Cobalt ferrite NPs coated with chitosan and polyethylene glycol were synthesized for the targeted delivery of resveratrol. CoFe2O4 NPs coated with CS/PEG loaded with RSV showed average size of 234.40 nm. Resveratrol was encapsulated (>95%) onto CoFe2O4 NPs coated with chitosan/PEG. RSV-loaded nanoparticles were effective as a scavenger of ABTS and DPPH radicals, suggesting applications in processes involving oxidative stress. RSV-loaded magnetic-polymeric NPs showed antibacterial activity against four Gram-negative and Gram-positive bacteria.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"161 - 173"},"PeriodicalIF":1.2,"publicationDate":"2023-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44776232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-29DOI: 10.1080/1539445X.2023.2169461
S. Oprea, V. Potolinca
ABSTRACT Polyurethanes are highly sought after polymer materials due to their exceptional properties. These properties can be expanded by including 2-hydroxyethyl salicylate in its chemical structure in order to obtain active polymer materials with anti-inflammatory and analgesic properties. These polymers can be used in the manufacture of footwear, stockings and clothing. Furthermore, in order to improve mechanical properties, glycerol and its derivatives with various hydroxy-aliphatic chains can be incorporated into the polyurethanes. Changing the chemical structure of the hard segment (through chain extender amount and crosslinker’s structure) may yield improved or modified properties and uses for these polyurethanes, which can be identified by investigating the structure–property relationships for these materials. The incorporation of a crosslinker with longer hydroxy-aliphatic chains (glycerol ethoxylate (Star-PEG)) has significantly improved the mechanical resistance of the polyurethane. At the same time, Star-PEG-polyurethane preserved its very good properties after a year of outdoor environmental exposure, without exposure to direct sunlight. The inclusion of the salicylate component in the polyurethane hard segments develops new and interesting ways to obtain polyurethane elastomers for biomedical applications. We intend to study in detail the medical properties of these polyurethane materials and their maintenance over time in a future paper.
{"title":"The inclusion of a salicylate derivative in polyurethane structures and its effect on the properties and the stability of polyurethanes exposed to weathering","authors":"S. Oprea, V. Potolinca","doi":"10.1080/1539445X.2023.2169461","DOIUrl":"https://doi.org/10.1080/1539445X.2023.2169461","url":null,"abstract":"ABSTRACT Polyurethanes are highly sought after polymer materials due to their exceptional properties. These properties can be expanded by including 2-hydroxyethyl salicylate in its chemical structure in order to obtain active polymer materials with anti-inflammatory and analgesic properties. These polymers can be used in the manufacture of footwear, stockings and clothing. Furthermore, in order to improve mechanical properties, glycerol and its derivatives with various hydroxy-aliphatic chains can be incorporated into the polyurethanes. Changing the chemical structure of the hard segment (through chain extender amount and crosslinker’s structure) may yield improved or modified properties and uses for these polyurethanes, which can be identified by investigating the structure–property relationships for these materials. The incorporation of a crosslinker with longer hydroxy-aliphatic chains (glycerol ethoxylate (Star-PEG)) has significantly improved the mechanical resistance of the polyurethane. At the same time, Star-PEG-polyurethane preserved its very good properties after a year of outdoor environmental exposure, without exposure to direct sunlight. The inclusion of the salicylate component in the polyurethane hard segments develops new and interesting ways to obtain polyurethane elastomers for biomedical applications. We intend to study in detail the medical properties of these polyurethane materials and their maintenance over time in a future paper.","PeriodicalId":22140,"journal":{"name":"Soft Materials","volume":"21 1","pages":"149 - 160"},"PeriodicalIF":1.2,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42975896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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