Pub Date : 2024-01-29DOI: 10.1186/s43168-024-00260-7
Rasha Mohamed Hendy, Mona Ahmed Elawady, Hend Elsayed Nasr, Rizk Sayed R. Sarhan
Obstructive sleep apnea (OSA) is accompanied by different metabolic disorders and is linked with a heightened incidence of cardiovascular diseases and death. The information actively engaged in relating obstructive sleep apnea and dyslipidemia is quite uncertain. This research intended to determine the correlation between obstructive sleep apnea severeness and lipid profile abnormalities. Our study involved 120 cases diagnosed with OSA, who came to the chest department: at Benha University Hospital from September 2021 to December 2022. Included patients indicated for polysomnography because of suspected sleep-breathing disorders. Full history and clinical examination, and full polysomnography and blood samples for lipid profile, were done for all the cases. Results A total of 120 patients were involved in the study. Most cases were severe OSA (70%). The mean age in severe obstructive sleep apnea was 44.04 years with SD 9.49, Males were 92.9% in severe OSA, and the mean BMI in severe OSA was 36.63 with SD 7.79. LDL was positively correlated with AHI and DI (significantly); triglycerides were positively correlated with AHI, DI, and min oxygen saturation (significantly); and HDL was negatively correlated with AHI and DI significantly. Among lipid profile variables, LDL was the most predictor for AHI severity. Conclusion Lipid abnormalities are associated with OSA severity. Patients diagnosed with obstructive sleep apnea should be screened for lipid profile to correct any abnormality, hoping to prevent their harmful effects.
阻塞性睡眠呼吸暂停（OSA）伴有不同的代谢紊乱，并与心血管疾病和死亡的高发病率有关。目前，有关阻塞性睡眠呼吸暂停与血脂异常的信息尚不明确。本研究旨在确定阻塞性睡眠呼吸暂停严重程度与血脂异常之间的相关性。本研究涉及 2021 年 9 月至 2022 年 12 月期间到本哈大学医院胸科就诊的 120 例确诊为 OSA 的患者。其中包括因疑似睡眠呼吸障碍而接受多导睡眠图检查的患者。对所有病例进行了全面的病史和临床检查，并进行了全面的多导睡眠图检查和血脂检查。结果 共有 120 名患者参与了研究。大多数病例为严重 OSA（70%）。重度阻塞性睡眠呼吸暂停患者的平均年龄为 44.04 岁，标准差为 9.49 岁；重度 OSA 患者中男性占 92.9%；重度 OSA 患者的平均体重指数为 36.63，标准差为 7.79。低密度脂蛋白与 AHI 和 DI 呈显著正相关；甘油三酯与 AHI、DI 和分钟血氧饱和度呈显著正相关；高密度脂蛋白与 AHI 和 DI 呈显著负相关。在血脂特征变量中，低密度脂蛋白对 AHI 严重程度的预测作用最大。结论 血脂异常与 OSA 严重程度有关。被诊断为阻塞性睡眠呼吸暂停的患者应进行血脂筛查，以纠正任何异常，希望能避免其有害影响。
{"title":"Correlation of obstructive sleep apnea severity and lipid profile level","authors":"Rasha Mohamed Hendy, Mona Ahmed Elawady, Hend Elsayed Nasr, Rizk Sayed R. Sarhan","doi":"10.1186/s43168-024-00260-7","DOIUrl":"https://doi.org/10.1186/s43168-024-00260-7","url":null,"abstract":"Obstructive sleep apnea (OSA) is accompanied by different metabolic disorders and is linked with a heightened incidence of cardiovascular diseases and death. The information actively engaged in relating obstructive sleep apnea and dyslipidemia is quite uncertain. This research intended to determine the correlation between obstructive sleep apnea severeness and lipid profile abnormalities. Our study involved 120 cases diagnosed with OSA, who came to the chest department: at Benha University Hospital from September 2021 to December 2022. Included patients indicated for polysomnography because of suspected sleep-breathing disorders. Full history and clinical examination, and full polysomnography and blood samples for lipid profile, were done for all the cases. Results A total of 120 patients were involved in the study. Most cases were severe OSA (70%). The mean age in severe obstructive sleep apnea was 44.04 years with SD 9.49, Males were 92.9% in severe OSA, and the mean BMI in severe OSA was 36.63 with SD 7.79. LDL was positively correlated with AHI and DI (significantly); triglycerides were positively correlated with AHI, DI, and min oxygen saturation (significantly); and HDL was negatively correlated with AHI and DI significantly. Among lipid profile variables, LDL was the most predictor for AHI severity. Conclusion Lipid abnormalities are associated with OSA severity. Patients diagnosed with obstructive sleep apnea should be screened for lipid profile to correct any abnormality, hoping to prevent their harmful effects.","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139588453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-25DOI: 10.1186/s43168-024-00259-0
Safy Zahid Kaddah, Merna Hamada Korany, Eman Kamal Ibrahim
Obstructive sleep apnea (OSA) and metabolic syndrome (MetS) are two diseases associated with an increased risk of cardio-metabolic complications and both share the same risk factors such as obesity and smoking. To study the clinical features and predictors of MetS in OSA patients. A cross-sectional study was conducted in the sleep lab of the Pulmonology Department at Kasr Al-Ainy Hospital, Cairo University, during the period from September 2022 to March 2023. Eighty OSA patients were included, and each patient was subjected to history taking, body measurements, blood pressure measurements, Epworth sleepiness scale, STOP-BANG score, polysomnography, and laboratory investigations including lipid profile and (HBA1C), MetS was defined based on the International Diabetes Federation (IDF) guidelines. Then patients were classified into two groups; OSA with MetS and OSA without MetS, we compared both groups using a one-way (ANOVA) test. MetS was diagnosed in 66.3% of the study group. OSA with MetS had higher BMI (44.76 ± 9.55) with significant p values (< 0.001), lower average O2 saturation % (90.23 ± 5.5, p value = 0.013), and longer SPO2 time < 90% (37.39 ± 34.14, p value = 0.034) than the other group. BMI, waist, hip, and neck circumferences and SPO2 < 90% were predictors of MetS among OSA patients with significant p values. Females had significantly higher BMI (46.64 ± 9.58), p value = 0.015. Males had significantly higher AHI than females (32.99 ± 24.02 versus 19.83 ± 14.74 respectively), p value = 0.031. MetS was diagnosed in 66.3% of OSA. BMI, neck, hip, waist circumferences, and SPO2 < 90% were predictors of MetS among OSA. Retrospectively registered, date of registration is 18/09/2023, and number of registration is NCT06051097 . The link to the study on clinicaltrials.gov.
{"title":"Clinical features and predictors of metabolic syndrome among obstructive sleep apnea patients","authors":"Safy Zahid Kaddah, Merna Hamada Korany, Eman Kamal Ibrahim","doi":"10.1186/s43168-024-00259-0","DOIUrl":"https://doi.org/10.1186/s43168-024-00259-0","url":null,"abstract":"Obstructive sleep apnea (OSA) and metabolic syndrome (MetS) are two diseases associated with an increased risk of cardio-metabolic complications and both share the same risk factors such as obesity and smoking. To study the clinical features and predictors of MetS in OSA patients. A cross-sectional study was conducted in the sleep lab of the Pulmonology Department at Kasr Al-Ainy Hospital, Cairo University, during the period from September 2022 to March 2023. Eighty OSA patients were included, and each patient was subjected to history taking, body measurements, blood pressure measurements, Epworth sleepiness scale, STOP-BANG score, polysomnography, and laboratory investigations including lipid profile and (HBA1C), MetS was defined based on the International Diabetes Federation (IDF) guidelines. Then patients were classified into two groups; OSA with MetS and OSA without MetS, we compared both groups using a one-way (ANOVA) test. MetS was diagnosed in 66.3% of the study group. OSA with MetS had higher BMI (44.76 ± 9.55) with significant p values (< 0.001), lower average O2 saturation % (90.23 ± 5.5, p value = 0.013), and longer SPO2 time < 90% (37.39 ± 34.14, p value = 0.034) than the other group. BMI, waist, hip, and neck circumferences and SPO2 < 90% were predictors of MetS among OSA patients with significant p values. Females had significantly higher BMI (46.64 ± 9.58), p value = 0.015. Males had significantly higher AHI than females (32.99 ± 24.02 versus 19.83 ± 14.74 respectively), p value = 0.031. MetS was diagnosed in 66.3% of OSA. BMI, neck, hip, waist circumferences, and SPO2 < 90% were predictors of MetS among OSA. Retrospectively registered, date of registration is 18/09/2023, and number of registration is NCT06051097 . The link to the study on clinicaltrials.gov.","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139588434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-22DOI: 10.1186/s43168-024-00256-3
Maha Mohammed Elgabry, Eman Shebl, Mohamed Saad El-Shetry, Enaam I. Elsayed, Niveen ELSayed Zayed
Point of care ultrasonography (POCUS) is a real time examination that can be used in the emergency room and intensive care unit (ICU). It can provide low-cost modality in short period of time that can help the clinician in better management the ICU patients. The aim of the current work was to evaluate the impact of POCUS (focused heart, lung, IVC and Doppler lower limb) in improving the outcome of deteriorating patients in the respiratory intensive care unit (RICU), via narrowing differential diagnosis and earlier start of target therapy. This prospective study included 126 deteriorated patients in the RICU. The POCUS was performed to all included patients, together with the indicated laboratory and radiological investigations (Chest x-ray, computerized tomography, and conventional echocardiography) to detect the agreement between POCUS and the gold standard techniques to assess the POCUS effectiveness. The impact of applying POCUS on the outcome of the studied patients was evaluated regarding ICU and in hospital length of stay and the 30-day mortality. The included patients were 51 males (40.5%) and 75 females (59.5%) with a mean ±SD of age 45.4 ± 15.7 years. POCUS showed a good agreement with the gold standard techniques. There was significant improvement in outcome of the studied patients as regard ICU and in hospital stay with early using of POCUS examination but no significant difference in 30 days mortality rate of the studied patients. POCUS is an effective modality in the management of deteriorating patients in the RICU with a good impact on the patient outcome.
{"title":"Role of point of care ultrasound in management of deteriorating respiratory intensive care unit patients and its impact on outcome","authors":"Maha Mohammed Elgabry, Eman Shebl, Mohamed Saad El-Shetry, Enaam I. Elsayed, Niveen ELSayed Zayed","doi":"10.1186/s43168-024-00256-3","DOIUrl":"https://doi.org/10.1186/s43168-024-00256-3","url":null,"abstract":"Point of care ultrasonography (POCUS) is a real time examination that can be used in the emergency room and intensive care unit (ICU). It can provide low-cost modality in short period of time that can help the clinician in better management the ICU patients. The aim of the current work was to evaluate the impact of POCUS (focused heart, lung, IVC and Doppler lower limb) in improving the outcome of deteriorating patients in the respiratory intensive care unit (RICU), via narrowing differential diagnosis and earlier start of target therapy. This prospective study included 126 deteriorated patients in the RICU. The POCUS was performed to all included patients, together with the indicated laboratory and radiological investigations (Chest x-ray, computerized tomography, and conventional echocardiography) to detect the agreement between POCUS and the gold standard techniques to assess the POCUS effectiveness. The impact of applying POCUS on the outcome of the studied patients was evaluated regarding ICU and in hospital length of stay and the 30-day mortality. The included patients were 51 males (40.5%) and 75 females (59.5%) with a mean ±SD of age 45.4 ± 15.7 years. POCUS showed a good agreement with the gold standard techniques. There was significant improvement in outcome of the studied patients as regard ICU and in hospital stay with early using of POCUS examination but no significant difference in 30 days mortality rate of the studied patients. POCUS is an effective modality in the management of deteriorating patients in the RICU with a good impact on the patient outcome.","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139559281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.1186/s43168-024-00255-4
Taha Taha Abdelgawad, Azza Eliwa, Ahmed Fouda, Doaa Khedr, Ramy A. Abdelsalam, Ahmed Elsayed Mansour
Recurrent exacerbations in COPD patients are associated with accelerated reduction in lung function. Airway inflammation and small airway dysfunction were recognized for a long time as an essential feature of COPD. To study the relationship between neutrophilic airway inflammation, small airway dysfunction, and frequency of acute exacerbations in COPD patients. This was a cross-sectional study. Thirty COPD patients were enrolled and classified into two groups: infrequent exacerbators (IFE) “who developed ≤ 1 exacerbation per year” and frequent exacerbators (FE) “who developed ≥ 2 exacerbations per year” in the last year prior to this study. All patients included in the study underwent clinical evaluation, and assessment of small airway dysfunction by pulmonary function testing (MEF 25–75, RV/TLC, and DLCO) and paired inspiratory and expiratory HRCT-chest to measure the mean lung density (MLD) as well as assessment of neutrophilic airway inflammation by taking BAL via bronchoscopy and examined for differential cell count. The small airway dysfunction is more severe in the case of the FE COPD group as there were statistically significant differences between FE and IFE COPD groups in %MEF 25–75 and RV/TLC (p = 0.038 and p = 0.030, respectively). The mean value of the BAL neutrophil % was higher in FE than in IFE COPD patients but without a significant statistical difference (p = 0.513). There were statistically significant negative correlations between %FEV1 (p = 0.026), %FVC (p = 0.020), and %MEF25–75 (p = 0.005) and MLD(E/I) in all studied COPD patients. COPD patients associated with small airway dysfunction and increased BAL neutrophil cell count are more prone to frequent exacerbations. ClinicalTrials.gov NCT06040931 . Registered 18 Sept 2023—Retrospectively registered.
慢性阻塞性肺病患者的病情反复加重与肺功能加速下降有关。气道炎症和小气道功能障碍是慢性阻塞性肺病的基本特征，这一点早已得到公认。研究慢性阻塞性肺病患者中性粒细胞气道炎症、小气道功能障碍和急性加重频率之间的关系。这是一项横断面研究。30名慢性阻塞性肺病患者被纳入研究，并被分为两组："每年病情加重次数≤1次 "的非经常加重者（IFE）和 "每年病情加重次数≥2次 "的经常加重者（FE）。所有参与研究的患者都接受了临床评估，并通过肺功能测试（MEF 25-75、RV/TLC 和 DLCO）和胸腔成对吸气和呼气 HRCT（测量平均肺密度 (MLD)）评估了小气道功能障碍，还通过支气管镜采集 BAL 评估了中性粒细胞气道炎症，并检查了细胞计数差异。FE COPD 组的小气道功能障碍更为严重，因为 FE 和 IFE COPD 组在 %MEF 25-75 和 RV/TLC 方面存在显著统计学差异（分别为 p = 0.038 和 p = 0.030）。FE COPD 患者的 BAL 中性粒细胞百分比平均值高于 IFE COPD 患者，但无显著统计学差异（p = 0.513）。在所有研究的慢性阻塞性肺病患者中，FEV1%（p = 0.026）、FVC%（p = 0.020）、MEF25-75%（p = 0.005）与 MLD(E/I)之间存在具有统计学意义的负相关。伴有小气道功能障碍和 BAL 中性粒细胞计数增加的慢性阻塞性肺病患者更容易出现频繁的病情加重。ClinicalTrials.gov NCT06040931 。2023 年 9 月 18 日注册-回顾性注册。
{"title":"Relationship between airway inflammation, small airway dysfunction, and frequency of acute exacerbations in patients with chronic obstructive pulmonary disease","authors":"Taha Taha Abdelgawad, Azza Eliwa, Ahmed Fouda, Doaa Khedr, Ramy A. Abdelsalam, Ahmed Elsayed Mansour","doi":"10.1186/s43168-024-00255-4","DOIUrl":"https://doi.org/10.1186/s43168-024-00255-4","url":null,"abstract":"Recurrent exacerbations in COPD patients are associated with accelerated reduction in lung function. Airway inflammation and small airway dysfunction were recognized for a long time as an essential feature of COPD. To study the relationship between neutrophilic airway inflammation, small airway dysfunction, and frequency of acute exacerbations in COPD patients. This was a cross-sectional study. Thirty COPD patients were enrolled and classified into two groups: infrequent exacerbators (IFE) “who developed ≤ 1 exacerbation per year” and frequent exacerbators (FE) “who developed ≥ 2 exacerbations per year” in the last year prior to this study. All patients included in the study underwent clinical evaluation, and assessment of small airway dysfunction by pulmonary function testing (MEF 25–75, RV/TLC, and DLCO) and paired inspiratory and expiratory HRCT-chest to measure the mean lung density (MLD) as well as assessment of neutrophilic airway inflammation by taking BAL via bronchoscopy and examined for differential cell count. The small airway dysfunction is more severe in the case of the FE COPD group as there were statistically significant differences between FE and IFE COPD groups in %MEF 25–75 and RV/TLC (p = 0.038 and p = 0.030, respectively). The mean value of the BAL neutrophil % was higher in FE than in IFE COPD patients but without a significant statistical difference (p = 0.513). There were statistically significant negative correlations between %FEV1 (p = 0.026), %FVC (p = 0.020), and %MEF25–75 (p = 0.005) and MLD(E/I) in all studied COPD patients. COPD patients associated with small airway dysfunction and increased BAL neutrophil cell count are more prone to frequent exacerbations. ClinicalTrials.gov NCT06040931 . Registered 18 Sept 2023—Retrospectively registered.","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139469973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-10DOI: 10.1186/s43168-023-00252-z
Rasha Mohamed Hendy, Basma H. Hani, Salwa H. Mohammed
Obstructive sleep apnea syndrome (OSAS) is a common disease that has a prevalence of 6 to 13% of the adult population. It is characterized by recurrent obstruction partial or total upper airway and subsequent paroxysmal nocturnal hypoxia, leading to intermittent arousals from sleep and excessive daytime sleepiness. This work aimed to evaluate the relationship between the hematological parameters in CBC with differential as a new biomarker showing systemic inflammation and as an indicator of OSAS severity. This retrospective cross-sectional analysis included 100 subjects with OSA from those attending Chest departments in Benha University Hospital from 2021 to 2022 and 2022 to 2023 period. All patients were subjected to full history taking and clinical examination, electrocardiogram, chest X-ray posteroanterior view, full night of polysomnography, and complete blood count with differential. There was a statistically significant difference between mild; moderate and severe OSA patients regarding platelets to lymphocyte ratio. A statistically significant difference between mild and severe OSA regarding neutrophil to lymphocyte ratio was found. There was a statistically significant positive correlation between OSA severity and platelet level, N/L, and P/L ratio. The hematological indices including neutrophil to lymphocyte ratio and platelet to lymphocyte ratio could be alternatives to expensive time-consuming biochemical markers to evaluate the inflammation and severity in the OSAS population.
阻塞性睡眠呼吸暂停综合征（OSAS）是一种常见疾病，发病率占成年人的 6% 至 13%。其特点是部分或全部上气道反复阻塞，随后出现阵发性夜间缺氧，导致间歇性睡眠唤醒和白天过度嗜睡。这项研究旨在评估全血细胞计数中的血液学参数与差值之间的关系，差值是显示全身炎症的新生物标志物，也是 OSAS 严重程度的指标。这项回顾性横断面分析包括 100 名 OSA 患者，他们分别来自 2021 年至 2022 年和 2022 年至 2023 年期间在本哈大学医院胸科就诊的患者。所有患者均接受了全面的病史采集和临床检查、心电图、胸部 X 光后正位、整夜多导睡眠图检查和全血细胞计数（含差值）。在血小板与淋巴细胞比率方面，轻度、中度和重度 OSA 患者之间的差异具有统计学意义。在中性粒细胞与淋巴细胞比率方面，轻度和重度 OSA 患者之间的差异具有统计学意义。在统计学上，OSA 严重程度与血小板水平、N/L 和 P/L 比率呈显著正相关。包括中性粒细胞与淋巴细胞比率和血小板与淋巴细胞比率在内的血液学指标可替代昂贵耗时的生化指标，用于评估 OSAS 患者的炎症和严重程度。
{"title":"Hematological parameters as predictors of OSA severity","authors":"Rasha Mohamed Hendy, Basma H. Hani, Salwa H. Mohammed","doi":"10.1186/s43168-023-00252-z","DOIUrl":"https://doi.org/10.1186/s43168-023-00252-z","url":null,"abstract":"Obstructive sleep apnea syndrome (OSAS) is a common disease that has a prevalence of 6 to 13% of the adult population. It is characterized by recurrent obstruction partial or total upper airway and subsequent paroxysmal nocturnal hypoxia, leading to intermittent arousals from sleep and excessive daytime sleepiness. This work aimed to evaluate the relationship between the hematological parameters in CBC with differential as a new biomarker showing systemic inflammation and as an indicator of OSAS severity. This retrospective cross-sectional analysis included 100 subjects with OSA from those attending Chest departments in Benha University Hospital from 2021 to 2022 and 2022 to 2023 period. All patients were subjected to full history taking and clinical examination, electrocardiogram, chest X-ray posteroanterior view, full night of polysomnography, and complete blood count with differential. There was a statistically significant difference between mild; moderate and severe OSA patients regarding platelets to lymphocyte ratio. A statistically significant difference between mild and severe OSA regarding neutrophil to lymphocyte ratio was found. There was a statistically significant positive correlation between OSA severity and platelet level, N/L, and P/L ratio. The hematological indices including neutrophil to lymphocyte ratio and platelet to lymphocyte ratio could be alternatives to expensive time-consuming biochemical markers to evaluate the inflammation and severity in the OSAS population.","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139421007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-02DOI: 10.1186/s43168-023-00253-y
Seham Ezzat Fathy Elfeky, Asmaa Ali, Eman M. Moazen, Mohammad Hamad Alhassoon, Nesma A. Elzanaty, Nouf Mubarak Alazmi, Liang Wu, Mai M. Saleh
Chronic inflammation plays a crucial role in developing various cardiovascular and metabolic disorders. Obstructive sleep apnea (OSA) is a unique condition characterized by the coexistence of cardiovascular and metabolic disturbances, where chronic inflammation may exacerbate disease progression and severity. This study investigated how different hematological inflammatory cells and mediators can serve as predictive indicators of severe OSA. In a retrospective cohort study, 150 patients suspected of having obstructive sleep apnea (OSA) underwent polysomnography (PSG) to confirm the diagnosis. Based on their apnea-hypopnea index (AHI), the patients were categorized into three groups: mild, moderate, and severe OSA. Blood samples were collected for the assessment of inflammatory blood cells and mediators at the time of diagnosis. Among the 150 patients studied, 90 were diagnosed with OSA, and 43 had severe OSA, representing a prevalence rate of 47.7%. Patients with severe OSA were notably older and more likely to have diabetes mellitus and hypertension. After adjusting for age and sex, each one-unit increase in Systemic Inflammatory Response Index (SIRI), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) levels was associated with a doubling in the likelihood of having moderate and severe OSA (p < 0.05 for all). However, hypertension was linked to a 16-fold increase in the likelihood of moderate and severe OSA (p = 0.01). Our research indicates that comorbidity and inflammatory cells and markers (SIRI, CRP, and ESR) are significantly related to the severity of OSA.
慢性炎症在各种心血管和新陈代谢疾病的发病过程中起着至关重要的作用。阻塞性睡眠呼吸暂停（OSA）是一种独特的疾病，其特点是心血管和代谢紊乱并存，慢性炎症可能会加剧疾病的发展和严重程度。本研究探讨了不同的血液炎症细胞和介质如何作为严重 OSA 的预测指标。在一项回顾性队列研究中，150 名疑似患有阻塞性睡眠呼吸暂停（OSA）的患者接受了多导睡眠图（PSG）检查以确诊。根据呼吸暂停-低通气指数（AHI），患者被分为三组：轻度、中度和重度 OSA。在诊断时采集血液样本以评估炎性血细胞和介质。在所研究的 150 名患者中，90 人被诊断为 OSA，43 人患有严重 OSA，患病率为 47.7%。严重 OSA 患者的年龄明显偏大，更有可能患有糖尿病和高血压。在对年龄和性别进行调整后，全身炎症反应指数（SIRI）、C反应蛋白（CRP）和红细胞沉降率（ESR）水平每增加一个单位，患中度和重度OSA的可能性就会增加一倍（P均小于0.05）。然而，高血压与中度和重度 OSA 的可能性增加 16 倍有关（p = 0.01）。我们的研究表明，合并症、炎症细胞和标志物（SIRI、CRP 和 ESR）与 OSA 的严重程度有显著关系。
{"title":"Systemic inflammatory response index as an independent predictor of severity in patients with obstructive sleep apnea","authors":"Seham Ezzat Fathy Elfeky, Asmaa Ali, Eman M. Moazen, Mohammad Hamad Alhassoon, Nesma A. Elzanaty, Nouf Mubarak Alazmi, Liang Wu, Mai M. Saleh","doi":"10.1186/s43168-023-00253-y","DOIUrl":"https://doi.org/10.1186/s43168-023-00253-y","url":null,"abstract":"Chronic inflammation plays a crucial role in developing various cardiovascular and metabolic disorders. Obstructive sleep apnea (OSA) is a unique condition characterized by the coexistence of cardiovascular and metabolic disturbances, where chronic inflammation may exacerbate disease progression and severity. This study investigated how different hematological inflammatory cells and mediators can serve as predictive indicators of severe OSA. In a retrospective cohort study, 150 patients suspected of having obstructive sleep apnea (OSA) underwent polysomnography (PSG) to confirm the diagnosis. Based on their apnea-hypopnea index (AHI), the patients were categorized into three groups: mild, moderate, and severe OSA. Blood samples were collected for the assessment of inflammatory blood cells and mediators at the time of diagnosis. Among the 150 patients studied, 90 were diagnosed with OSA, and 43 had severe OSA, representing a prevalence rate of 47.7%. Patients with severe OSA were notably older and more likely to have diabetes mellitus and hypertension. After adjusting for age and sex, each one-unit increase in Systemic Inflammatory Response Index (SIRI), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) levels was associated with a doubling in the likelihood of having moderate and severe OSA (p < 0.05 for all). However, hypertension was linked to a 16-fold increase in the likelihood of moderate and severe OSA (p = 0.01). Our research indicates that comorbidity and inflammatory cells and markers (SIRI, CRP, and ESR) are significantly related to the severity of OSA.","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139083608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-02DOI: 10.1186/s43168-023-00254-x
Rehab Elmeazawy, Ahmed Mohammed Farid EL-Moazen
Children with COVID-19 infection had fewer severe symptoms, which made it challenging to publish clinical data for this age group. This study aimed to determine the clinical features, laboratory markers, and predictors of mortality in children hospitalized in Pediatric Critical Care Units with COVID-19 pneumonia. This retrospective research included all children between the age of ≥ 1 month and 18 years with laboratory-confirmed COVID-19 pneumonia through reverse transcriptase polymerase chain reaction (RT-PCR) from nasopharyngeal swabs who were admitted to Pediatric Critical Care Units between January 2022 and December 2022. The study included 62 patients with confirmed COVID-19 infection. Out of the 62 patients, 43 (69.4%) survived and 19 (30.6%) succumbed. High-grade fever, cough, altered level of consciousness, convulsion, CO-RADS IV, elevated blood CRP, urea, D-dimer, ferritin, and sodium were linked to significantly higher mortality risk. (OR: 15.867, p = 0.001, OR: 1.543, p = 0.044, OR: 7.321, p = 0.026, OR: 15.00, p = 0.017, OR: 10.833, p = 0.001, OR: 1.015, p = 0.032, OR: 1.028, p = 0.040, OR: 3.315, p < 0.0001, OR: 1.004, p = 0.049, OR: 1.111, p = 0.006 respectively). Our study revealed high in-hospital mortality among critically ill children with confirmed COVID-19 pneumonia. Identification of critically ill children with risk factors for death, such as high-grade fever, cough, altered consciousness, convulsion, CO-RADS IV and V, and raised inflammatory markers at the time of admission could minimize excess mortality during COVID-19 waves.
感染 COVID-19 的儿童严重症状较少，因此公布这一年龄组的临床数据具有挑战性。本研究旨在确定在儿科重症监护病房住院的 COVID-19 肺炎患儿的临床特征、实验室指标和死亡率预测因素。这项回顾性研究纳入了所有在2022年1月至2022年12月期间入住儿科重症监护病房、通过鼻咽拭子反转录聚合酶链反应（RT-PCR）实验室确诊为COVID-19肺炎的≥1个月至18岁儿童。研究包括 62 名确诊感染 COVID-19 的患者。在62名患者中，43人（69.4%）存活，19人（30.6%）死亡。高烧、咳嗽、意识改变、抽搐、CO-RADS IV、血 CRP、尿素、D-二聚体、铁蛋白和钠升高与死亡率风险显著升高有关。(OR：15.867，P = 0.001；OR：1.543，P = 0.044；OR：7.321，P = 0.026；OR：15.00，P = 0.017；OR：10.833，P = 0.001；OR：1.015，P = 0.032；OR：1.028，P = 0.040；OR：3.315, p < 0.0001, OR: 1.004, p = 0.049, OR: 1.111, p = 0.006）。我们的研究显示，确诊为 COVID-19 肺炎的重症患儿院内死亡率很高。识别具有死亡风险因素的重症患儿，如高烧、咳嗽、意识改变、抽搐、CO-RADS IV 和 V 级、入院时炎症标志物升高等，可最大限度地降低 COVID-19 波期间过高的死亡率。
{"title":"Predictors of mortality in critically ill children hospitalized with laboratory- confirmed COVID-19 pneumonia","authors":"Rehab Elmeazawy, Ahmed Mohammed Farid EL-Moazen","doi":"10.1186/s43168-023-00254-x","DOIUrl":"https://doi.org/10.1186/s43168-023-00254-x","url":null,"abstract":"Children with COVID-19 infection had fewer severe symptoms, which made it challenging to publish clinical data for this age group. This study aimed to determine the clinical features, laboratory markers, and predictors of mortality in children hospitalized in Pediatric Critical Care Units with COVID-19 pneumonia. This retrospective research included all children between the age of ≥ 1 month and 18 years with laboratory-confirmed COVID-19 pneumonia through reverse transcriptase polymerase chain reaction (RT-PCR) from nasopharyngeal swabs who were admitted to Pediatric Critical Care Units between January 2022 and December 2022. The study included 62 patients with confirmed COVID-19 infection. Out of the 62 patients, 43 (69.4%) survived and 19 (30.6%) succumbed. High-grade fever, cough, altered level of consciousness, convulsion, CO-RADS IV, elevated blood CRP, urea, D-dimer, ferritin, and sodium were linked to significantly higher mortality risk. (OR: 15.867, p = 0.001, OR: 1.543, p = 0.044, OR: 7.321, p = 0.026, OR: 15.00, p = 0.017, OR: 10.833, p = 0.001, OR: 1.015, p = 0.032, OR: 1.028, p = 0.040, OR: 3.315, p < 0.0001, OR: 1.004, p = 0.049, OR: 1.111, p = 0.006 respectively). Our study revealed high in-hospital mortality among critically ill children with confirmed COVID-19 pneumonia. Identification of critically ill children with risk factors for death, such as high-grade fever, cough, altered consciousness, convulsion, CO-RADS IV and V, and raised inflammatory markers at the time of admission could minimize excess mortality during COVID-19 waves.","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139083676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.1186/s43168-023-00249-8
E. Fatma, Gamal A. Rahman, M. Algendy, M. Mahmoud, A. Mona, T. Yousra
Stiff index is defined as the proportion of lung tissue elasticity in relation to chest wall elasticity to pertain to its cyclic tidal volume. It is meant to reflect the risk of overloading lung pressure. Introducing the Stiff index into bedside management determines the pressure needed to keep the lung open with no risk of barotrauma. Aim of the work The primary endpoint was to highlight the stiff index in ARDS patients as a potential surrogate for detecting the changes in lung mechanics and the assumptions underlying the estimation of relevant respiratory parameters. Secondly, we aimed to assess intrathoracic pressure ITP in view of chest wall elastance Ecw in relation to respiratory system elastance Ers within the same population. Subjects and methods Data were collected from forty ARDS patients, diagnosed according to Berlin definition, who were admitted to ICUS Ain Shams University hospitals during the period between December 2022 and April 2023. These populations were patients’ purposive samples who underwent volume‐controlled ventilation at least 2 days prior to study enrollment. Their mean age was 64.68 ± 15.01 years with males (N = 22) to females (N = 18) ratio 55%. Measurements of peak airway pressure, plateau pressure, and delta airway pressure change ∆Paw measured three times on end-expiratory (ee) and on end-inspiratory (ei) occlusion tests, and the higher of the three readings were reported. Results The calculated mean Stiff index was (0.66 ± 0.159) which was correlated with Peak pressure (r = − 0.377, P = 0.017) and with trans-pulmonary end inspiration TPPei (r = 0.312, P = 0.05). The stiff index was also found to be correlated with intra-thoracic pressure ITP (r = 0.769, P 0.001), but is not statistically significant with inspiratory tidal volume (r = 0.132, P 0.416). Conclusion Lung pressure loading in ARDS could be recognized by estimating an increase in stiff index. The cut point of stiff factor that limited the plateau at or below 30 cmH2o was 0.75 with 71% sensitivity and 0.63% specificity, respectively. The more the Stiff index the more was the ITP, and it had no relation to TV.
{"title":"Bedside test for estimating stiff index in mechanically ventilated ARDS patient: a pilot study","authors":"E. Fatma, Gamal A. Rahman, M. Algendy, M. Mahmoud, A. Mona, T. Yousra","doi":"10.1186/s43168-023-00249-8","DOIUrl":"https://doi.org/10.1186/s43168-023-00249-8","url":null,"abstract":"Stiff index is defined as the proportion of lung tissue elasticity in relation to chest wall elasticity to pertain to its cyclic tidal volume. It is meant to reflect the risk of overloading lung pressure. Introducing the Stiff index into bedside management determines the pressure needed to keep the lung open with no risk of barotrauma. Aim of the work The primary endpoint was to highlight the stiff index in ARDS patients as a potential surrogate for detecting the changes in lung mechanics and the assumptions underlying the estimation of relevant respiratory parameters. Secondly, we aimed to assess intrathoracic pressure ITP in view of chest wall elastance Ecw in relation to respiratory system elastance Ers within the same population. Subjects and methods Data were collected from forty ARDS patients, diagnosed according to Berlin definition, who were admitted to ICUS Ain Shams University hospitals during the period between December 2022 and April 2023. These populations were patients’ purposive samples who underwent volume‐controlled ventilation at least 2 days prior to study enrollment. Their mean age was 64.68 ± 15.01 years with males (N = 22) to females (N = 18) ratio 55%. Measurements of peak airway pressure, plateau pressure, and delta airway pressure change ∆Paw measured three times on end-expiratory (ee) and on end-inspiratory (ei) occlusion tests, and the higher of the three readings were reported. Results The calculated mean Stiff index was (0.66 ± 0.159) which was correlated with Peak pressure (r = − 0.377, P = 0.017) and with trans-pulmonary end inspiration TPPei (r = 0.312, P = 0.05). The stiff index was also found to be correlated with intra-thoracic pressure ITP (r = 0.769, P 0.001), but is not statistically significant with inspiratory tidal volume (r = 0.132, P 0.416). Conclusion Lung pressure loading in ARDS could be recognized by estimating an increase in stiff index. The cut point of stiff factor that limited the plateau at or below 30 cmH2o was 0.75 with 71% sensitivity and 0.63% specificity, respectively. The more the Stiff index the more was the ITP, and it had no relation to TV.","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138715400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13DOI: 10.1186/s43168-023-00247-w
Rania Ahmad Sweed, Rana Alsaeed Rizk Abd Elghany, Anwar Ahmed Elganady, Enas Elsayed Mohamed, Jaidaa Farouk Mekky, Mohamed Mahmoud Elshafei
Obstructive sleep apnea disrupts the normal sleep cycle and is associated with many adverse consequences such as cardiovascular disease, DM, psychological problems, depression, decreased cognitive function, reduced quality of life, structural brain changes, and fatigue. This work aimed to study the MRI structural brain changes and to assess the neurocognitive function, depression, and fatigue using multiple questionnaires (MoCA score, BDI-П, and FSS, respectively) in OSA patients. We enrolled 30 patients > 18 years with moderate (severity groups І), severe (severity groups П), very severe or extremely severe OSA (severity groups Ш), and 10 control subjects that were matched. All patients and control subjects underwent full-night PSG. Patients underwent neuropsychological tests including the Montreal Cognitive Assessment, Beck’s Depression Inventory-II, and Fatigue Severity Scale (FSS) in addition to an MRI brain without contrast. The mean AHI among patients (56.7% were females and 43.3% were males) was 39.97 ± 20.26 event/h. Severity groups І (40% of studied patients), П (46.7%), and Ш (13.3%). Abnormal MRI findings (WMCs) were detected in 18 patients (60%), versus 4 subjects (40%) in the control group, showing no statistically significant difference, p = 0.300. Among different severity groups, the prevalence of abnormal MRI findings was 4 (33.3%), 11 (78.6%), and 3 (75%) patients in severity groups І, П, and Ш, respectively. There was a statistically significant difference between patients and control regarding affection of subcortical and corpus callosal regions, p = 0.007 and 0.38, respectively, but not periventricular or deep white matter hyperintensities. Montreal Cognitive Assessment, Beck’s Depression Inventory-II score, and Fatigue Severity Scale, all showed statistically significant differences between patient and control groups. There was a significant negative correlation between AHI and MoCA score and a significant positive correlation between AHI and BDI-П, and also between AHI and FSS, p = 0.005, 0.016, and 0.008, respectively. The Frontal lobe was the most affected lobe among our patients followed by the parietal lobe. The mean value of AHI in the group of patients with abnormal MRI findings was statistically significantly higher than that in the group with normal MRI findings (45.42 ± 19.29 versus 32.06 ± 19.82 event/h, respectively), p = 0.010. Comparing both groups showed: that the mean value of MoCA score in the group of patients with abnormal MRI findings was significantly lower than that in the group with normal MRI findings (17.89 ± 3.64 versus 24.08 ± 4.44, respectively), p < 0.001. Regarding both BDI-П and FSS, it was noted that the mean value in the group of patients with abnormal MRI findings was higher than that in the group with normal MRI findings (33.83 ± 7.94 versus 32 ± 7.39, and (58.39 ± 4.82 versus 55.17 ± 7.12 respectively), but this difference was not statistically significant, p = 0.529, p = 1.000, respectivel
{"title":"Impact of obstructive sleep apnea on cognition, mood, and fatigue: an MRI-based study","authors":"Rania Ahmad Sweed, Rana Alsaeed Rizk Abd Elghany, Anwar Ahmed Elganady, Enas Elsayed Mohamed, Jaidaa Farouk Mekky, Mohamed Mahmoud Elshafei","doi":"10.1186/s43168-023-00247-w","DOIUrl":"https://doi.org/10.1186/s43168-023-00247-w","url":null,"abstract":"Obstructive sleep apnea disrupts the normal sleep cycle and is associated with many adverse consequences such as cardiovascular disease, DM, psychological problems, depression, decreased cognitive function, reduced quality of life, structural brain changes, and fatigue. This work aimed to study the MRI structural brain changes and to assess the neurocognitive function, depression, and fatigue using multiple questionnaires (MoCA score, BDI-П, and FSS, respectively) in OSA patients. We enrolled 30 patients > 18 years with moderate (severity groups І), severe (severity groups П), very severe or extremely severe OSA (severity groups Ш), and 10 control subjects that were matched. All patients and control subjects underwent full-night PSG. Patients underwent neuropsychological tests including the Montreal Cognitive Assessment, Beck’s Depression Inventory-II, and Fatigue Severity Scale (FSS) in addition to an MRI brain without contrast. The mean AHI among patients (56.7% were females and 43.3% were males) was 39.97 ± 20.26 event/h. Severity groups І (40% of studied patients), П (46.7%), and Ш (13.3%). Abnormal MRI findings (WMCs) were detected in 18 patients (60%), versus 4 subjects (40%) in the control group, showing no statistically significant difference, p = 0.300. Among different severity groups, the prevalence of abnormal MRI findings was 4 (33.3%), 11 (78.6%), and 3 (75%) patients in severity groups І, П, and Ш, respectively. There was a statistically significant difference between patients and control regarding affection of subcortical and corpus callosal regions, p = 0.007 and 0.38, respectively, but not periventricular or deep white matter hyperintensities. Montreal Cognitive Assessment, Beck’s Depression Inventory-II score, and Fatigue Severity Scale, all showed statistically significant differences between patient and control groups. There was a significant negative correlation between AHI and MoCA score and a significant positive correlation between AHI and BDI-П, and also between AHI and FSS, p = 0.005, 0.016, and 0.008, respectively. The Frontal lobe was the most affected lobe among our patients followed by the parietal lobe. The mean value of AHI in the group of patients with abnormal MRI findings was statistically significantly higher than that in the group with normal MRI findings (45.42 ± 19.29 versus 32.06 ± 19.82 event/h, respectively), p = 0.010. Comparing both groups showed: that the mean value of MoCA score in the group of patients with abnormal MRI findings was significantly lower than that in the group with normal MRI findings (17.89 ± 3.64 versus 24.08 ± 4.44, respectively), p < 0.001. Regarding both BDI-П and FSS, it was noted that the mean value in the group of patients with abnormal MRI findings was higher than that in the group with normal MRI findings (33.83 ± 7.94 versus 32 ± 7.39, and (58.39 ± 4.82 versus 55.17 ± 7.12 respectively), but this difference was not statistically significant, p = 0.529, p = 1.000, respectivel","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138579573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tube thoracostomy stands as the conventional treatment for pleural diseases. Nevertheless, pigtail catheters have gained traction due to their smaller size, potentially resulting in reduced complications. Despite the enhanced safety and ease of insertion associated with pigtail catheters, it is crucial to recognize that procedural complications can arise irrespective of the drainage method employed. Complications related to small-bore pigtail catheters encompass the possibilities of dislodgment, kinking, and, though rarely, breakage. Our case serves as a reminder for medical practitioners to select appropriately sized pleural tubes based on the specific pleural condition. In this instance, we present the utilization of a semi-rigid thoracoscope to extract a broken pigtail catheter from the pleural cavity. To the best of our knowledge, this is the first case report of removing a broken pleural catheter using semi-rigid medical thoracoscopy.
{"title":"Successful removal of an iatrogenic pleural foreign body—pigtail catheter, using a semi-rigid thoracoscope","authors":"Pradeep Bajad, Sourabh Pahuja, Arjun Khanna, Satyam Agarwal","doi":"10.1186/s43168-023-00250-1","DOIUrl":"https://doi.org/10.1186/s43168-023-00250-1","url":null,"abstract":"Tube thoracostomy stands as the conventional treatment for pleural diseases. Nevertheless, pigtail catheters have gained traction due to their smaller size, potentially resulting in reduced complications. Despite the enhanced safety and ease of insertion associated with pigtail catheters, it is crucial to recognize that procedural complications can arise irrespective of the drainage method employed. Complications related to small-bore pigtail catheters encompass the possibilities of dislodgment, kinking, and, though rarely, breakage. Our case serves as a reminder for medical practitioners to select appropriately sized pleural tubes based on the specific pleural condition. In this instance, we present the utilization of a semi-rigid thoracoscope to extract a broken pigtail catheter from the pleural cavity. To the best of our knowledge, this is the first case report of removing a broken pleural catheter using semi-rigid medical thoracoscopy.","PeriodicalId":22426,"journal":{"name":"The Egyptian Journal of Bronchology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138523846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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