Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.363731
M. A. Fadey, Zeyad Mohsen Elbagoury, A. A. Dawood, Yaser H Metwally, Mohamed E. Hasan, Ayman T. Mohamed
Background : Enhanced recovery programs (ERP) have emerged to enhance surgical outcomes and decrease expenses. However, these are still opposed by the traditional measures in the treatment of colorectal carcinoma Objectives : This study aimed to compare laparoscopic versus open left-side cancer colon resection under the guidelines of ERP. Subjects and methods : sixty-two patients with left side cancer colon were divided into two equal groups: group (A) received laparoscopic colectomy (LC) and group (B) received open colectomy (OC). ERP were applied. Follow-up was planned for 1 month for the early outcomes. Result s: the mean age of the included subjects was 49.2 ± 6.23 and 47.8 ± 6.9 years in LC and OC groups respectively. There was a significantly less hospital stay in LC group when compared with OC group (P=0.001). Significantly more pain was reported in OC Group (P=0.001%). There was a significant difference regarding postoperative complications where Postoperative nausea and vomiting (PONV), ileus, wound infection and wound dehiscence were statistically higher in OC group when compared with patients who received LC (P=0.001). Conclusion: Laparoscopic left-sided colectomy, when establishing ERP, is safer, more dependable, easier to use, and more appropriate than open left-sided colon cancer surgery—especially when performed by skilled surgeons with fewer postoperative problems and shorter hospital stays.
{"title":"Feasibility and Outcome of Enhanced Recovery Programs in Laparoscopic versus Open Elective Colectomy for Left Side Colonic Carcinoma Surgery","authors":"M. A. Fadey, Zeyad Mohsen Elbagoury, A. A. Dawood, Yaser H Metwally, Mohamed E. Hasan, Ayman T. Mohamed","doi":"10.21608/ejhm.2024.363731","DOIUrl":"https://doi.org/10.21608/ejhm.2024.363731","url":null,"abstract":"Background : Enhanced recovery programs (ERP) have emerged to enhance surgical outcomes and decrease expenses. However, these are still opposed by the traditional measures in the treatment of colorectal carcinoma Objectives : This study aimed to compare laparoscopic versus open left-side cancer colon resection under the guidelines of ERP. Subjects and methods : sixty-two patients with left side cancer colon were divided into two equal groups: group (A) received laparoscopic colectomy (LC) and group (B) received open colectomy (OC). ERP were applied. Follow-up was planned for 1 month for the early outcomes. Result s: the mean age of the included subjects was 49.2 ± 6.23 and 47.8 ± 6.9 years in LC and OC groups respectively. There was a significantly less hospital stay in LC group when compared with OC group (P=0.001). Significantly more pain was reported in OC Group (P=0.001%). There was a significant difference regarding postoperative complications where Postoperative nausea and vomiting (PONV), ileus, wound infection and wound dehiscence were statistically higher in OC group when compared with patients who received LC (P=0.001). Conclusion: Laparoscopic left-sided colectomy, when establishing ERP, is safer, more dependable, easier to use, and more appropriate than open left-sided colon cancer surgery—especially when performed by skilled surgeons with fewer postoperative problems and shorter hospital stays.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141713424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.363596
Sondos Mokhtar, Elsayed Nassar, A. G. Safan, Ezzeldin Saleh, Mohamed Ibrahim, Mohamed Abdelrahman Salem
Background: It is widely recognized that the primary benefits of minimally invasive surgery are reduced postoperative discomfort and faster recovery time for physical activities. Objectives: To assess the efficacy of analgesics for preoperative oblique subcostal transverse abdominis blocks (TAP) and lateral TAP blocks for cases undergoing elective laparoscopic cholecystectomy (ELLC). Patients and methods: This was a prospective controlled randomized study performed on 48 cases admitted to the day case surgery unit of Menoufia University Hospital for whom an ELLC was scheduled. Cases were randomly divided into 3 equal groups using SPSS. Results: There wasn't a significant distinction among the 3 groups regarding HR measurements at any time pre-or postoperatively (p > 0.05). There wasn’t significant variation among the three groups as regard end tidal CO 2 measurements at any time intraoperatively (p > 0.05). There wasn’t significant variance among the 3 groups regarding mean arterial blood pressures (MAP) measurements at 30 min intraoperatively, at baseline, 15 min, 4, 6, and 24 h postoperatively (p > 0.05). While there was a significant distinction among the three groups regarding MAP measurements at 10, 20 min intraoperatively, 2 h, and 12 h postoperatively (p<0.05). Conclusion: The utilization of an ultrasound-guided (ESP) block resulted in a greater reduction in postoperative tramadol usage and pain scores compared to the oblique subcostal transversus abdominis plane block following ELLC surgery.
{"title":"Comparison between the Analgesic Effect of Oblique Subcostal and Lateral Approach of Ultrasound-Guided Transverse Abdominis Blocks for Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Controlled Trial","authors":"Sondos Mokhtar, Elsayed Nassar, A. G. Safan, Ezzeldin Saleh, Mohamed Ibrahim, Mohamed Abdelrahman Salem","doi":"10.21608/ejhm.2024.363596","DOIUrl":"https://doi.org/10.21608/ejhm.2024.363596","url":null,"abstract":"Background: It is widely recognized that the primary benefits of minimally invasive surgery are reduced postoperative discomfort and faster recovery time for physical activities. Objectives: To assess the efficacy of analgesics for preoperative oblique subcostal transverse abdominis blocks (TAP) and lateral TAP blocks for cases undergoing elective laparoscopic cholecystectomy (ELLC). Patients and methods: This was a prospective controlled randomized study performed on 48 cases admitted to the day case surgery unit of Menoufia University Hospital for whom an ELLC was scheduled. Cases were randomly divided into 3 equal groups using SPSS. Results: There wasn't a significant distinction among the 3 groups regarding HR measurements at any time pre-or postoperatively (p > 0.05). There wasn’t significant variation among the three groups as regard end tidal CO 2 measurements at any time intraoperatively (p > 0.05). There wasn’t significant variance among the 3 groups regarding mean arterial blood pressures (MAP) measurements at 30 min intraoperatively, at baseline, 15 min, 4, 6, and 24 h postoperatively (p > 0.05). While there was a significant distinction among the three groups regarding MAP measurements at 10, 20 min intraoperatively, 2 h, and 12 h postoperatively (p<0.05). Conclusion: The utilization of an ultrasound-guided (ESP) block resulted in a greater reduction in postoperative tramadol usage and pain scores compared to the oblique subcostal transversus abdominis plane block following ELLC surgery.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141705703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.368088
Assem Herzallah
Background: Managing exposed groin vascular grafts after vascular interventions can be challenging. Rescuing these conduits saves a patient's extremity and sometimes their life. Objective: This study aimed to emphasize the efficacy and safety of the sartorius muscle flap for the salvage of infected groin wounds. Patients and methods: This prospective study included 5 patients with infected or threatened groin wounds after femoral artery open intervention, who underwent sartorius muscle flap surgery between January 2020 and December 2022 at Mataria Teaching Hospital, Cairo, Egypt. Results: This study presents the outcomes of utilizing sartorius muscle flaps for managing infected or at-risk femoral wounds. The initial surgeries involved femoral thrombectomy in one trauma case, femoral artery repair for one patient with a femoral pseudoaneurysm post-PCI, and femoropopliteal bypass with a saphenous graft in three patients. Following the sartorius muscle flap procedures, all patients achieved complete wound healing. Primary wound closure was successfully attained in all five cases, with an average healing duration of one month. There was no failure in the vascular reconstructions, observed over a median follow-up period of six months. Conclusion: The use of sartorius muscle flaps by vascular surgeons can aid in the healing of infected groin wounds while preserving graft patency and ensuring limb salvage.
{"title":"The Sartorius Muscle Transposition: A Brilliant Solution for Infected Groin Wounds Including Vascular Conduits","authors":"Assem Herzallah","doi":"10.21608/ejhm.2024.368088","DOIUrl":"https://doi.org/10.21608/ejhm.2024.368088","url":null,"abstract":"Background: Managing exposed groin vascular grafts after vascular interventions can be challenging. Rescuing these conduits saves a patient's extremity and sometimes their life. Objective: This study aimed to emphasize the efficacy and safety of the sartorius muscle flap for the salvage of infected groin wounds. Patients and methods: This prospective study included 5 patients with infected or threatened groin wounds after femoral artery open intervention, who underwent sartorius muscle flap surgery between January 2020 and December 2022 at Mataria Teaching Hospital, Cairo, Egypt. Results: This study presents the outcomes of utilizing sartorius muscle flaps for managing infected or at-risk femoral wounds. The initial surgeries involved femoral thrombectomy in one trauma case, femoral artery repair for one patient with a femoral pseudoaneurysm post-PCI, and femoropopliteal bypass with a saphenous graft in three patients. Following the sartorius muscle flap procedures, all patients achieved complete wound healing. Primary wound closure was successfully attained in all five cases, with an average healing duration of one month. There was no failure in the vascular reconstructions, observed over a median follow-up period of six months. Conclusion: The use of sartorius muscle flaps by vascular surgeons can aid in the healing of infected groin wounds while preserving graft patency and ensuring limb salvage.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.368091
Eman Gamal, Eldin Helal, Eman Refaat, Aisha Emhammed, Almokhtar Aljaghmani
Background: Cisplatin, while potent against cancer, causes significant nephrotoxicity and hepatotoxicity. Objective: To investigate the protective effects of curcumin and flaxseed oil against cisplatin-induced toxicity. Materials and Methods: Animal models (rats) were divided into four groups: a control group, a cisplatin-alone group (single dose of 7.5 mg/kg i.p. on day six), a curcumin group, and a flaxseed oil group (0.1 ml/1 kg orally for ten days with a cisplatin dose on day six). Liver and kidney functions were assessed by measuring serum (alanine transaminase) ALT, aspartate aminotransferase (AST), urea, and creatinine levels. Protein metabolism was evaluated by measuring total protein, albumin, and globulin levels, and the albumin/globulin ratio, followed by histological examination of liver and kidney biopsies. Results: Cisplatin significantly increased ALT, AST, urea, and creatinine levels indicating severe liver and kidney damage (p < 0.001). It also decreased total protein, albumin, and globulin levels, impairing protein metabolism (p < 0.001). Co-administration of curcumin or flaxseed with cisplatin significantly reduced ALT, AST, urea, and creatinine levels, while improving total protein, albumin, and globulin levels and improved histological results compared to the cisplatin-alone group. Conclusion: Curcumin and flaxseed effectively mitigated cisplatin-induced hepatotoxicity, nephrotoxicity, and disturbances in protein metabolism. Thus, they could be potential adjuvant therapies in cisplatin chemotherapy to reduce its side effects.
{"title":"The Protective Effects of Curcumin Oil and Flaxseed Oil on Cisplatin-Induced Nephrotoxicity and Hepatotoxicity in Male Albino Rats","authors":"Eman Gamal, Eldin Helal, Eman Refaat, Aisha Emhammed, Almokhtar Aljaghmani","doi":"10.21608/ejhm.2024.368091","DOIUrl":"https://doi.org/10.21608/ejhm.2024.368091","url":null,"abstract":"Background: Cisplatin, while potent against cancer, causes significant nephrotoxicity and hepatotoxicity. Objective: To investigate the protective effects of curcumin and flaxseed oil against cisplatin-induced toxicity. Materials and Methods: Animal models (rats) were divided into four groups: a control group, a cisplatin-alone group (single dose of 7.5 mg/kg i.p. on day six), a curcumin group, and a flaxseed oil group (0.1 ml/1 kg orally for ten days with a cisplatin dose on day six). Liver and kidney functions were assessed by measuring serum (alanine transaminase) ALT, aspartate aminotransferase (AST), urea, and creatinine levels. Protein metabolism was evaluated by measuring total protein, albumin, and globulin levels, and the albumin/globulin ratio, followed by histological examination of liver and kidney biopsies. Results: Cisplatin significantly increased ALT, AST, urea, and creatinine levels indicating severe liver and kidney damage (p < 0.001). It also decreased total protein, albumin, and globulin levels, impairing protein metabolism (p < 0.001). Co-administration of curcumin or flaxseed with cisplatin significantly reduced ALT, AST, urea, and creatinine levels, while improving total protein, albumin, and globulin levels and improved histological results compared to the cisplatin-alone group. Conclusion: Curcumin and flaxseed effectively mitigated cisplatin-induced hepatotoxicity, nephrotoxicity, and disturbances in protein metabolism. Thus, they could be potential adjuvant therapies in cisplatin chemotherapy to reduce its side effects.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141842009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.368097
Noura Shaker, Osama El, Mohamed Saad, Noura Abd, El Hay, Shaker El Sayed
Background: Headache is a commonly reported comorbidity in individuals with epilepsy and their relationship is still incompletely known. Objective: To assess the most prevalent kinds of primary headache and their connection to seizure timing among patients with epilepsy. Patients and methods: This is cross sectional study, we assessed headaches using a comprehensive medical history, physical and neurologic examination, EEG, CT, and MRI brain scans in 200 patients with idiopathic epilepsy who were seen at the Mansoura University Hospital's neurology outpatient clinic and epilepsy clinic. Results: Of our study population, tension-type headache (TTH) occurred in 57% of patients, unclassified headache in 22% of patients, migraine occurred in 19% of patients, migraine and TTH in 2% of patients. There were 4 patients (2%) had a pre-ictal headache, 2 patients (1%) had an ictal headache, 156 patients (78%) had a postictal headache and 31 patients (15.5%) had an interictal headache and 7 patients (3.5%) had an inter-ictal-post-ictal headache. Headache frequency was associated with female sex, anxiety, sadness, generalized tonic-clonic epilepsy, high seizure frequency, and antiepileptic polytherapy usage. Conclusion: A major comorbidity of epilepsy is headache, particularly TTH, which should be given extra attention, particularly in female patients, patients receiving polytherapy, patients experiencing more frequent seizures, and patients with generalized tonic-clonic epilepsy.
{"title":"Seizure Associated Headache in Epilepsy","authors":"Noura Shaker, Osama El, Mohamed Saad, Noura Abd, El Hay, Shaker El Sayed","doi":"10.21608/ejhm.2024.368097","DOIUrl":"https://doi.org/10.21608/ejhm.2024.368097","url":null,"abstract":"Background: Headache is a commonly reported comorbidity in individuals with epilepsy and their relationship is still incompletely known. Objective: To assess the most prevalent kinds of primary headache and their connection to seizure timing among patients with epilepsy. Patients and methods: This is cross sectional study, we assessed headaches using a comprehensive medical history, physical and neurologic examination, EEG, CT, and MRI brain scans in 200 patients with idiopathic epilepsy who were seen at the Mansoura University Hospital's neurology outpatient clinic and epilepsy clinic. Results: Of our study population, tension-type headache (TTH) occurred in 57% of patients, unclassified headache in 22% of patients, migraine occurred in 19% of patients, migraine and TTH in 2% of patients. There were 4 patients (2%) had a pre-ictal headache, 2 patients (1%) had an ictal headache, 156 patients (78%) had a postictal headache and 31 patients (15.5%) had an interictal headache and 7 patients (3.5%) had an inter-ictal-post-ictal headache. Headache frequency was associated with female sex, anxiety, sadness, generalized tonic-clonic epilepsy, high seizure frequency, and antiepileptic polytherapy usage. Conclusion: A major comorbidity of epilepsy is headache, particularly TTH, which should be given extra attention, particularly in female patients, patients receiving polytherapy, patients experiencing more frequent seizures, and patients with generalized tonic-clonic epilepsy.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141848766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.363589
Hoda A.A. Shaheen, Walaa A. Elkholy, Hoda Abdel, Aziz Shaheen
Background: Giardia intestinalis is a flagellate protozoan that infects both humans and animals. Formation of reactive oxygen species (ROS) during several physiological processes in tissues and cells is indicative of the pathogenesis of different parasitic infections involving Giardia lamblia. Objectives: the current study aimed to assess the potential effects of Punica granatum on interactions of G. intestinalis with the intestinal barrier and its role in ameliorating oxidative stress in a murine model using serum biochemical analysis of both malondialdehyde (MDA) and reduced glutathione (GSH). Methodology: Five experimental groups were involved: Group I included control healthy, group II included infected untreated, group III included infected-treated with metronidazole, group IV included infected-treated with P. granatum , Group V received P. granatum for seven days before and also during induction of infection then regular administration of the drug for an additional seven days. Results: The highest serum levels of MDA (nmol/ml) were expressed in group II 7.03 ± 0.19 followed by group IV that was 5.29 ± 0.62 then group V 4.17 ± 0.28, while group III had 3.58 ± 0.18. On the other side, the highest serum levels of GSH (nmol/ml) were expressed in group V 9.93 ± 0.18, followed by group IV 7.41 ± 0.19 nmol/ml, while in group III was 6.11 ± 0.40. Group II had 5.00 ± 0.15 nmol/ml. There was significant difference between different groups. Conclusions: Decreased expression of MDA in prophylactic and treated groups by P. granatum , moreover increased expression of GSH in group V prophylactic group explains the protective effect of P. granatum against lipid peroxidation and oxidative stress induced by Giardia infection.
{"title":"Effect of Punica Granatum Peels Methanolic Extract on Interactions of Giardia Intestinalis with the Intestinal Barrier in Murine Model: Lipid Peroxidation and Oxidative Stress","authors":"Hoda A.A. Shaheen, Walaa A. Elkholy, Hoda Abdel, Aziz Shaheen","doi":"10.21608/ejhm.2024.363589","DOIUrl":"https://doi.org/10.21608/ejhm.2024.363589","url":null,"abstract":"Background: Giardia intestinalis is a flagellate protozoan that infects both humans and animals. Formation of reactive oxygen species (ROS) during several physiological processes in tissues and cells is indicative of the pathogenesis of different parasitic infections involving Giardia lamblia. Objectives: the current study aimed to assess the potential effects of Punica granatum on interactions of G. intestinalis with the intestinal barrier and its role in ameliorating oxidative stress in a murine model using serum biochemical analysis of both malondialdehyde (MDA) and reduced glutathione (GSH). Methodology: Five experimental groups were involved: Group I included control healthy, group II included infected untreated, group III included infected-treated with metronidazole, group IV included infected-treated with P. granatum , Group V received P. granatum for seven days before and also during induction of infection then regular administration of the drug for an additional seven days. Results: The highest serum levels of MDA (nmol/ml) were expressed in group II 7.03 ± 0.19 followed by group IV that was 5.29 ± 0.62 then group V 4.17 ± 0.28, while group III had 3.58 ± 0.18. On the other side, the highest serum levels of GSH (nmol/ml) were expressed in group V 9.93 ± 0.18, followed by group IV 7.41 ± 0.19 nmol/ml, while in group III was 6.11 ± 0.40. Group II had 5.00 ± 0.15 nmol/ml. There was significant difference between different groups. Conclusions: Decreased expression of MDA in prophylactic and treated groups by P. granatum , moreover increased expression of GSH in group V prophylactic group explains the protective effect of P. granatum against lipid peroxidation and oxidative stress induced by Giardia infection.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141696932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.366546
Ahmad Ali Abdo, Hani Abdelshafook Khalaf
Background: Contrast-induced nephropathy (CIN) refers to a temporary decline in kidney function after using iodinated contrast agents. Identifying high-risk patients and implementing suitable preventive measures are crucial for reducing CIN incidence. Objective: This study aimed to investigate risks associated with CIN after percutaneous coronary interventions (PCI). Patients and methods: This prospective observational study included 500 patients aged 18 years or older with a glomerular filtration rate (GFR) of 60 ml/min/1.73 m² or higher who underwent PCI at Al-Husain University Hospital between January 2022 and August 2023. Results: Hypertension significantly increased the risk of AKI after PCI [adjusted OR = 15.34 (4.77-60.36, p<0.001)]. Adjustment of hemoglobin level significantly decreased the risk of AKI [adjusted OR = 0.26 (0.12-0.53, p<0.001)] but an increased level of LDL increased the risk of AKI after PCI [adjusted OR = 1.05 (1.02-1.08, p=0.002)] and decrease of HDL level below normal significantly increased the level of AKI [adjusted OR = 1.21 (1.03-1.46, p=0.030)]. Conclusion: Hypertension, dyslipidemia, contrast volume, and impaired cardiac parameters significantly increased the risk of AKI following PCI, while higher hemoglobin levels were protective.
背景：造影剂诱发肾病（CIN）是指使用碘造影剂后肾功能暂时性下降。识别高危患者并采取适当的预防措施对降低 CIN 发病率至关重要。研究目的本研究旨在调查经皮冠状动脉介入治疗（PCI）后与 CIN 相关的风险。患者和方法：这项前瞻性观察研究纳入了 500 名年龄在 18 岁或以上、肾小球滤过率 (GFR) 在 60 ml/min/1.73 m² 或以上、于 2022 年 1 月至 2023 年 8 月期间在 Al-Husain 大学医院接受 PCI 治疗的患者。结果高血压会明显增加PCI术后发生AKI的风险[调整后OR = 15.34 (4.77-60.36, p<0.001)]。调整血红蛋白水平可明显降低发生 AKI 的风险[调整 OR = 0.26 (0.12-0.53, p<0.001)]，但低密度脂蛋白水平升高会增加 PCI 后发生 AKI 的风险[调整 OR = 1.05 (1.02-1.08, p=0.002)]，而高密度脂蛋白水平降至正常以下会明显增加发生 AKI 的风险[调整 OR = 1.21 (1.03-1.46, p=0.030)]。结论高血压、血脂异常、造影剂量和心脏参数受损会明显增加PCI术后发生AKI的风险，而较高的血红蛋白水平则具有保护作用。
{"title":"Risk Factors of Contrast-Induced Nephropathy after Percutaneous Coronary Interventions: An Observational Study","authors":"Ahmad Ali Abdo, Hani Abdelshafook Khalaf","doi":"10.21608/ejhm.2024.366546","DOIUrl":"https://doi.org/10.21608/ejhm.2024.366546","url":null,"abstract":"Background: Contrast-induced nephropathy (CIN) refers to a temporary decline in kidney function after using iodinated contrast agents. Identifying high-risk patients and implementing suitable preventive measures are crucial for reducing CIN incidence. Objective: This study aimed to investigate risks associated with CIN after percutaneous coronary interventions (PCI). Patients and methods: This prospective observational study included 500 patients aged 18 years or older with a glomerular filtration rate (GFR) of 60 ml/min/1.73 m² or higher who underwent PCI at Al-Husain University Hospital between January 2022 and August 2023. Results: Hypertension significantly increased the risk of AKI after PCI [adjusted OR = 15.34 (4.77-60.36, p<0.001)]. Adjustment of hemoglobin level significantly decreased the risk of AKI [adjusted OR = 0.26 (0.12-0.53, p<0.001)] but an increased level of LDL increased the risk of AKI after PCI [adjusted OR = 1.05 (1.02-1.08, p=0.002)] and decrease of HDL level below normal significantly increased the level of AKI [adjusted OR = 1.21 (1.03-1.46, p=0.030)]. Conclusion: Hypertension, dyslipidemia, contrast volume, and impaired cardiac parameters significantly increased the risk of AKI following PCI, while higher hemoglobin levels were protective.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141707106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.363588
Abdelhakeem Foad Elwany, Yasser Mohammed, Hassan Mandour, Abobakr Elshafy, Semon Sameh, Samy Samaan, Omnia Z. Elshebl, Mostafa Gomaa
Background: For a long time, the hypertrophied tonsils impact on velopharyngeal closure has been a point of concern. Objectives: To identify the alterations in the velopharyngeal valve (VPV) closure patterns following adenotonsillectomy in Arabic-speaking children, to predict the incidence of complications as nasal regurgitation or open nasality. Patients and methods: This observational prospective research was performed on 100 patients, with hypertrophied adenoid and tonsils, who were collected from outpatient clinic of Benha University Hospitals. All cases underwent preoperative laboratory investigations, otorhinolaryngology examination and video-nasoendoscopy and speech assessment before and after adenotonsillectomy. Results: The VP closure pattern was insignificantly different between both groups. However, the Nasality was significantly different among the 3 studied periods (P<0.001). There was no relation between gender and VP closure pattern preoperatively and 1 month after surgery. Regarding the postoperative nasality (hypernasality), the most prevalent observed VP closure patterns were both coronal and circular ones. Conclusions: The coronal pattern of closure of the VPV is the most prevalent type, which remains even postoperatively, also the type of closure has no significant value in predicting outcoming hypernasality.
{"title":"Effect of Adenotonsillectomy on Velopharyngeal Closure Patterns","authors":"Abdelhakeem Foad Elwany, Yasser Mohammed, Hassan Mandour, Abobakr Elshafy, Semon Sameh, Samy Samaan, Omnia Z. Elshebl, Mostafa Gomaa","doi":"10.21608/ejhm.2024.363588","DOIUrl":"https://doi.org/10.21608/ejhm.2024.363588","url":null,"abstract":"Background: For a long time, the hypertrophied tonsils impact on velopharyngeal closure has been a point of concern. Objectives: To identify the alterations in the velopharyngeal valve (VPV) closure patterns following adenotonsillectomy in Arabic-speaking children, to predict the incidence of complications as nasal regurgitation or open nasality. Patients and methods: This observational prospective research was performed on 100 patients, with hypertrophied adenoid and tonsils, who were collected from outpatient clinic of Benha University Hospitals. All cases underwent preoperative laboratory investigations, otorhinolaryngology examination and video-nasoendoscopy and speech assessment before and after adenotonsillectomy. Results: The VP closure pattern was insignificantly different between both groups. However, the Nasality was significantly different among the 3 studied periods (P<0.001). There was no relation between gender and VP closure pattern preoperatively and 1 month after surgery. Regarding the postoperative nasality (hypernasality), the most prevalent observed VP closure patterns were both coronal and circular ones. Conclusions: The coronal pattern of closure of the VPV is the most prevalent type, which remains even postoperatively, also the type of closure has no significant value in predicting outcoming hypernasality.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141690740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.363745
M. Dorrah, Salma Elnoamany, Yahya Samir Ahmed, Ahmed F. Gadelmawla, Amany Ragab, Zahraa M. Mahdy, Mostafa Shawky Afifi, Maram Atef, Donna Sabry Ayyad, Zeinab Abdel, Aziz Kasemy
Background: Intrauterine device (IUD) is one of the widely adopted contraceptive methods all over the world, especially in developing countries such as Egypt. The study aimed to assess the psychological effects and pain in Egyptian females on their first use of IUD. Subjects and Methods: Multicenter longitudinal cross-sectional study, started from June 2018 till July 2022, in the tertiary hospitals in 7 Egyptian governorates. About 553 participants were subjected to a pre-designed validated questionnaire including data on pain and psychological effect of IUD insertion with its different forms. Results: Psychological effects of IUD were felt more at insertion but later on they changed greatly from marked to not being detected, however, there was a slight increase in pain and discomfort later on after insertion (P<0.001). The absence of knowledge about IUD insertion was present in 44.3% of the participants. Knowing how IUD is inserted was associated with the presences of these psychological effects (P=0.014 and <0.001 respectively). There was an association between male doctor gender and less psychological effects and pain (P<0.001). Conclusion: There were negative psychological effects and pain among Egyptian women during the insertion of IUDs. Also, there was a low level of awareness about the IUD in most of the females.
{"title":"Is There Any Psychological Harm During IUD Insertion among Egyptian Women? A Multi-Centric Cross-Sectional Study","authors":"M. Dorrah, Salma Elnoamany, Yahya Samir Ahmed, Ahmed F. Gadelmawla, Amany Ragab, Zahraa M. Mahdy, Mostafa Shawky Afifi, Maram Atef, Donna Sabry Ayyad, Zeinab Abdel, Aziz Kasemy","doi":"10.21608/ejhm.2024.363745","DOIUrl":"https://doi.org/10.21608/ejhm.2024.363745","url":null,"abstract":"Background: Intrauterine device (IUD) is one of the widely adopted contraceptive methods all over the world, especially in developing countries such as Egypt. The study aimed to assess the psychological effects and pain in Egyptian females on their first use of IUD. Subjects and Methods: Multicenter longitudinal cross-sectional study, started from June 2018 till July 2022, in the tertiary hospitals in 7 Egyptian governorates. About 553 participants were subjected to a pre-designed validated questionnaire including data on pain and psychological effect of IUD insertion with its different forms. Results: Psychological effects of IUD were felt more at insertion but later on they changed greatly from marked to not being detected, however, there was a slight increase in pain and discomfort later on after insertion (P<0.001). The absence of knowledge about IUD insertion was present in 44.3% of the participants. Knowing how IUD is inserted was associated with the presences of these psychological effects (P=0.014 and <0.001 respectively). There was an association between male doctor gender and less psychological effects and pain (P<0.001). Conclusion: There were negative psychological effects and pain among Egyptian women during the insertion of IUDs. Also, there was a low level of awareness about the IUD in most of the females.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141697304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/ejhm.2024.366547
Aya A. Sayed, Ali M. Ali, Emad El-Din, N. Hassan, Sahar N. Ahmed, Aya Ahmed, Sayed Hussein
Background : Prostate cancer is a prevalent and serious health concern among men, with various treatment options available, including androgen deprivation therapy (ADT), radiotherapy, and surgery, each having distinct outcomes. Objective : This study evaluates the treatment outcomes of prostate cancer patients at Sohag University Hospital from 2017 to 2021. Patients and Methods : A retrospective cohort study was conducted on 49 prostate cancer patients. Data on demographics, cancer staging, Gleason scores, treatment modalities, and outcomes were analyzed. Results : The mean age of patients was 70.51 years. A significant proportion (53.1%) were diagnosed with high-risk locally advanced prostate cancer, and 42.9% had metastatic cancer. ADT was administered to 95.9% of patients, and 38.8% received radiotherapy. Overall survival (OS) rates were 100% at 1 year, 88.9% at 3 years, and 66.7% at 5 years. The duration of hormonal treatment significantly impacted OS, while no significant differences were noted across age, T stage, and Gleason score subgroups. Conclusions : The study highlights the severity of treated prostate cancer cases and the high overall survival rates. The duration of hormonal treatment was a significant factor in overall survival, emphasizing the importance of treatment duration management.
{"title":"Outcome of Treatment of Prostate Cancer at Sohag University Hospital between 2017 to 2021","authors":"Aya A. Sayed, Ali M. Ali, Emad El-Din, N. Hassan, Sahar N. Ahmed, Aya Ahmed, Sayed Hussein","doi":"10.21608/ejhm.2024.366547","DOIUrl":"https://doi.org/10.21608/ejhm.2024.366547","url":null,"abstract":"Background : Prostate cancer is a prevalent and serious health concern among men, with various treatment options available, including androgen deprivation therapy (ADT), radiotherapy, and surgery, each having distinct outcomes. Objective : This study evaluates the treatment outcomes of prostate cancer patients at Sohag University Hospital from 2017 to 2021. Patients and Methods : A retrospective cohort study was conducted on 49 prostate cancer patients. Data on demographics, cancer staging, Gleason scores, treatment modalities, and outcomes were analyzed. Results : The mean age of patients was 70.51 years. A significant proportion (53.1%) were diagnosed with high-risk locally advanced prostate cancer, and 42.9% had metastatic cancer. ADT was administered to 95.9% of patients, and 38.8% received radiotherapy. Overall survival (OS) rates were 100% at 1 year, 88.9% at 3 years, and 66.7% at 5 years. The duration of hormonal treatment significantly impacted OS, while no significant differences were noted across age, T stage, and Gleason score subgroups. Conclusions : The study highlights the severity of treated prostate cancer cases and the high overall survival rates. The duration of hormonal treatment was a significant factor in overall survival, emphasizing the importance of treatment duration management.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141709758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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