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Standalone Anterior Reconstruction Approach in Traumatic Cervical Spine Instability Lesions 创伤性颈椎不稳定病变的独立前路重建方法
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.349084
K. Kenawy, Amr M. Tayel, A. Abdelhameid
Background: The subaxial cervical spine trauma associated with spinal cord injury carries high rate of morbidity, mortality, with significant socioeconomic impact. There are different modalities for treatment of such cases. Objective: To evaluate the early outcome of standalone anterior reconstruction cervical spine surgery with cage and plate system in management of displaced subaxial cervical spine injuries with cord compression. Patients and Methods: The study included 14 patients during the period from January 2020 to January 2024 with displaced subaxial cervical spine injuries associated with cord compression. Preoperative symptoms and postoperative results for those patients who underwent standalone anterior reconstruction of cervical spine by surgery with cage and plate system for treatment of their lesions, were all recorded. Results: Patients were 9 males and 5 females with mean age 28 years. The most common cervical level affected was C5-C6 accounting for (71.5%) 10 cases, followed by C4-C5 3 cases (21.5%) then C6-C7 (7 case). The average blood loss intraoperatively was 150 ml ± 50. The most common complication was the C5 palsy occurred in 4 cases who improved with medical treatment and follow up. No CSF leak, hardware failure, vascular injury or soft tissue injuries were reported in this series. Conclusion: Performing immediate intraoperative closed reduction under general anesthesia for subaxial cervical spine dislocations, along with anterior cervical stabilization using a cage and plate system, has been shown to be the preferred treatment option due to its high safety and efficacy rates, with fewer complications.
背景:与脊髓损伤相关的颈椎下轴外伤具有很高的发病率和死亡率,并对社会经济产生重大影响。治疗此类病例的方法多种多样。目的评估在治疗伴有脊髓压迫的移位性亚轴向颈椎损伤时,独立前路重建颈椎手术与椎笼和椎板系统的早期疗效。患者和方法:研究纳入了 2020 年 1 月至 2024 年 1 月期间 14 例移位性颈椎轴下损伤伴脊髓压迫的患者。这些患者均接受了独立的颈椎前路重建手术,并使用笼和板系统治疗其病变,所有患者的术前症状和术后结果均被记录在案。结果患者中有 9 名男性和 5 名女性,平均年龄为 28 岁。最常见的颈椎水平是 C5-C6,占 10 例(71.5%),其次是 C4-C5 3 例(21.5%),然后是 C6-C7(7 例)。术中平均失血量为 150 毫升 ± 50 毫升。最常见的并发症是 4 例 C5 麻痹,经药物治疗和随访后好转。该系列手术未报告 CSF 渗漏、硬件故障、血管损伤或软组织损伤。结论在全身麻醉下对颈椎轴下脱位进行术中即刻闭合复位,同时使用颈椎笼和钢板系统进行颈椎前路稳定,因其安全性高、有效率高、并发症少,已被证明是首选的治疗方案。
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引用次数: 0
Vaginismus as a Cause of Unconsummated Marriage: An Egyptian Case Series 阴道炎是导致未婚先孕的原因之一:埃及病例系列
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.349388
AbdelMaguid I. Ramzy
Background: Vaginismus, a prevalent genito-pelvic pain/penetration disorder in the Middle East, often leads to unconsummated marriages, with a significant impact on marital and social well-being. Traditional treatments have shown limited success in refractory cases. Objective: To evaluate the effectiveness of an integrated treatment program, including Botulinum Toxin A (BTXA) injections, gradual vaginal introitus dilation, and psychological support, in treating refractory vaginismus in Egyptian women. Patients and Methods: This retrospective case series analyzed 1,400 women with refractory vaginismus, treated between January 2013 and 2023. The program comprised BTXA injections in the perineal muscles, followed by guided physiotherapy for muscle dilation and psychological counseling. Success was defined as painless vaginal penetration. Results: Of the initial 1,512 cases, 1,400 completed the program. The average age of participants was 28 years. Most patients (93%) had tried conventional treatments without success. Post-treatment, 92.6% (1,288/1,400) achieved painless penetration. The majority required 3 to 5 dilatation treatment sessions for success. Mild adverse effects were reported in 28% of cases. Conclusion: The integrated treatment program, combining BTXA injections, gradual dilation, and psychological support, is highly effective in managing refractory vaginismus in Egyptian women, with a success rate of over 90%. This approach offers a promising solution for couples facing unconsummated marriages due to vaginismus.
背景:阴道炎是中东地区普遍存在的一种生殖器盆腔疼痛/插入障碍,常常导致未婚先孕,对婚姻和社会福祉造成严重影响。传统治疗方法对难治性病例的疗效有限。研究目的评估综合治疗方案(包括注射肉毒杆菌毒素 A (BTXA)、逐步扩张阴道内口和心理支持)治疗埃及女性难治性阴道炎的效果。患者和方法:该回顾性病例系列分析了2013年1月至2023年期间接受治疗的1400名难治性阴道炎女性。治疗方案包括在会阴部肌肉注射 BTXA,然后在指导下进行肌肉扩张理疗和心理辅导。成功的定义是无痛插入阴道。结果:在最初的 1512 个病例中,有 1400 人完成了项目。参与者的平均年龄为 28 岁。大多数患者(93%)曾尝试过传统疗法,但未获成功。治疗后,92.6%(1,288/1,400)的患者实现了无痛插入。大多数患者需要 3 至 5 次扩张治疗才能成功。28%的病例出现轻微不良反应。结论综合治疗方案结合了 BTXA 注射、逐步扩张和心理支持,对治疗埃及妇女的难治性阴道炎非常有效,成功率超过 90%。这种方法为因阴道炎而面临婚姻破裂的夫妇提供了一种很有前景的解决方案。
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引用次数: 0
Role of Lactoferrin in Prevention of Premature Rupture of Membranes 乳铁蛋白在预防胎膜早破中的作用
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.349086
Mohammed Abd, Elhady Mohammed, Amr Ali, Sharaf Eldeen, Amira Emam Ahmed, Mai Abd, Elgelil Abd, Elmoneem Boshnak
Background: The development of the fetal membranes “amnion and chorion” begins with embryogenesis, although they do not have a direct role in the formation of the embryo or fetus. Objective: This study aimed to decrease the morbidities and mortalities resulting from premature rupture of membranes (PROM.). Patients and methods: This was a cohort study conducted on 90 patients at Department of Obstetrics and Gynecology in Benha University Hospital and Zagazig General Hospital through the period from November 2022 to November 2023. Results: A notable divergence was observed concerning the cervical length, with the first measurement yielding a p-value of 0.005 and the second measurement yielding a p-value of 0.01. Furthermore, a significant disparity was noted in the gestational age at the time of termination, as evidenced by a p-value of 0.029. When evaluating the effectiveness of lactoferrin (LF) in averting membrane rupture, lactoferrin demonstrated a sensitivity of 75.6%, a specificity of 57.8%, and predictive values for positive and negative outcomes of 64.2% and 70.3% respectively, albeit with a non-significant p-value of 0.163. In terms of neonatal vital signs (including pulse rate and respiratory rate) and neonatal weight, no significant differences were discerned, as indicated by p-values of 0.69, 0.545, 0.013, and 0.091, respectively. Conclusion: Augmentation through lactoferrin supplementation presents a conceivable strategy to diminish the incidence of PROM. Additional research is imperative to substantiate the preliminary evidence, which offers a significant conceptual foundation for the prospective utilization of lactoferrin in thwarting preterm childbirth.
背景:胎膜 "羊膜和绒毛膜 "的发育始于胚胎形成过程,但它们在胚胎或胎儿的形成过程中并不直接发挥作用。研究目的本研究旨在降低胎膜早破(PROM)导致的发病率和死亡率。患者和方法:这是一项队列研究,在 2022 年 11 月至 2023 年 11 月期间对贝哈大学医院妇产科和扎加齐格综合医院的 90 名患者进行了研究。研究结果在宫颈长度方面发现了明显的差异,第一次测量的 p 值为 0.005,第二次测量的 p 值为 0.01。此外,终止妊娠时的胎龄也存在明显差异,P 值为 0.029。在评估乳铁蛋白(LF)在避免胎膜破裂方面的效果时,乳铁蛋白的敏感性为 75.6%,特异性为 57.8%,对阳性和阴性结果的预测值分别为 64.2% 和 70.3%,尽管 p 值为 0.163,但并不显著。在新生儿生命体征(包括脉搏和呼吸频率)和新生儿体重方面,没有发现显著差异,P 值分别为 0.69、0.545、0.013 和 0.091。结论通过补充乳铁蛋白来增加妊娠率是降低妊娠前危险因素发生率的一种可行策略。这些初步证据为今后利用乳铁蛋白阻止早产提供了重要的概念基础。
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引用次数: 0
Predictive Factors of Refractory Epilepsy 难治性癫痫的预测因素
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.348716
Mohamed Magdy Ezzat, Mohamed El-Said, S. Attia, Mohamed Abd-ElSalam Mohamed
Background: Several epileptic patients give no response to the usual line of treatment, which represents 1/5 of epileptic patients and is known as drug-resistant epilepsy (DRE). DRE is often accompanied by impaired intellectual functions, psychiatric co-morbidities, physical damage, and low quality of life (QoL). Objective: This study aimed to assess the predictive factors for early identification of refractory seizures. Patients and Methods: This was a cross-section study conducted during a period of one year at Emergency Department (ED), Faculty of Medicine, Mansoura University. We comprised cases with diagnosis of refractory epilepsy on a total of 80 patients with refractory seizures [at least 2 potentially effective anti-epileptic drugs (AEDs) whatever mono or combined in maximally tolerated dose]. Results: Of the studied cases, 62.5% were females. There was a significant difference in cases with refractory epilepsy as regard seizures types with higher frequency of mixed and focal seizures. There was no statistically significant difference recorded regarding the previous history of status epilepticus (SE). Mixed seizures were significantly increased among cases with refractory epilepsy. The presence of positive family history, positive history of febrile seizures, associated psychiatric disorders and younger age at disease onset increase risk of refractory epilepsy. Conclusion: The main predictors of development of DRE were high initial seizures frequency, positive family history, febrile seizures, associated psychiatric disorders and younger age at disease onset.
背景:一些癫痫患者对常规治疗无效,占癫痫患者总数的 1/5,被称为耐药性癫痫(DRE)。耐药癫痫通常伴有智力功能受损、精神并发症、身体损伤和生活质量低下(QoL)。研究目的本研究旨在评估早期识别难治性癫痫发作的预测因素。患者和方法这是一项横断面研究,在曼苏尔大学医学院急诊科(ED)进行,为期一年。共有 80 名难治性癫痫患者被诊断为难治性癫痫(至少 2 种潜在有效的抗癫痫药物 (AED),无论单药还是联合用药均达到最大耐受剂量)。研究结果研究病例中,62.5%为女性。难治性癫痫患者的发作类型存在明显差异,混合型和局灶性发作频率较高。既往有癫痫状态(SE)病史的病例在统计学上没有明显差异。在难治性癫痫患者中,混合型癫痫发作明显增多。有阳性家族史、阳性发热性癫痫发作史、伴有精神障碍以及发病年龄较小,都会增加难治性癫痫的风险。结论预测难治性癫痫发病的主要因素是初始癫痫发作频率高、家族史阳性、发热性癫痫发作、伴有精神障碍和发病年龄较小。
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引用次数: 0
Study of Platelet-Rich Plasma Local Injection in Idiopathic Carpal Tunnel Syndrome 富血小板血浆局部注射治疗特发性腕管综合征的研究
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.348392
Samar G. Soliman, Alaa A. Labeeb, Saga F. El-Gazzar, Aya M. Allam
Background: Carpal tunnel syndrome (CTS) is one of the most diagnosed disabling conditions of the upper extremities. Corticosteroid local injection is one of the traditional treatments. Platelet-Rich Plasma (PRP) local injection has emerged as a new treatment, promoting nerve regeneration. Objectives: Comparison of the effectiveness of a single PRP local injection to a single corticosteroid local injection for treating idiopathic CTS using nerve conduction studies and Visual Analog Scale. Patients and method: 40 patients with mild idiopathic CTS were diagnosed clinically and selected according to Padua's Neurophysiologic Severity Scale (PNSS) started the study. They were divided into 2 equal groups; the first group of patients received a single local corticosteroid injection, and the second group received a single local PRP injection. Nerve conduction studies (NCS) in the form of median nerve sensory conduction velocity and the Visual Analogue Scale (VAS) were compared in both groups before and three months after injection. Results: Our study included 40 patients randomly grouped into two equal main categories. Group I (corticosteroid group) included 20 patients with a mean age of 41.50±11.26 years, while Group II (PRP group) included 20 patients with a mean age of 39.10±11.24 years. VAS and median nerve sensory conduction velocity were significantly reduced in group II compared to group I. Conclusions: PRP single local injection in the wrist proved to be better than corticosteroids single local injection for managing mild idiopathic CTS.
背景:腕管综合征(CTS)是上肢最常见的致残性疾病之一。皮质类固醇局部注射是传统治疗方法之一。富血小板血浆(PRP)局部注射已成为一种新的治疗方法,可促进神经再生。研究目的使用神经传导研究和视觉模拟量表比较单次富血小板血浆局部注射和单次皮质类固醇局部注射治疗特发性 CTS 的效果。患者和方法根据帕多瓦神经生理学严重程度量表(PNSS)筛选出的 40 名轻度特发性 CTS 患者经临床诊断后开始研究。他们被分为两组,第一组接受单次局部皮质类固醇注射,第二组接受单次局部 PRP 注射。比较两组患者在注射前和注射后三个月的正中神经感觉传导速度(NCS)和视觉模拟量表(VAS)。研究结果我们的研究将 40 名患者随机分为两组。第一组(皮质类固醇组)包括 20 名患者,平均年龄(41.50±11.26)岁;第二组(PRP 组)包括 20 名患者,平均年龄(39.10±11.24)岁。与第一组相比,第二组的 VAS 和正中神经感觉传导速度明显降低:事实证明,在治疗轻度特发性 CTS 方面,腕部单次局部注射 PRP 比单次局部注射皮质类固醇效果更好。
{"title":"Study of Platelet-Rich Plasma Local Injection in Idiopathic Carpal Tunnel Syndrome","authors":"Samar G. Soliman, Alaa A. Labeeb, Saga F. El-Gazzar, Aya M. Allam","doi":"10.21608/ejhm.2024.348392","DOIUrl":"https://doi.org/10.21608/ejhm.2024.348392","url":null,"abstract":"Background: Carpal tunnel syndrome (CTS) is one of the most diagnosed disabling conditions of the upper extremities. Corticosteroid local injection is one of the traditional treatments. Platelet-Rich Plasma (PRP) local injection has emerged as a new treatment, promoting nerve regeneration. Objectives: Comparison of the effectiveness of a single PRP local injection to a single corticosteroid local injection for treating idiopathic CTS using nerve conduction studies and Visual Analog Scale. Patients and method: 40 patients with mild idiopathic CTS were diagnosed clinically and selected according to Padua's Neurophysiologic Severity Scale (PNSS) started the study. They were divided into 2 equal groups; the first group of patients received a single local corticosteroid injection, and the second group received a single local PRP injection. Nerve conduction studies (NCS) in the form of median nerve sensory conduction velocity and the Visual Analogue Scale (VAS) were compared in both groups before and three months after injection. Results: Our study included 40 patients randomly grouped into two equal main categories. Group I (corticosteroid group) included 20 patients with a mean age of 41.50±11.26 years, while Group II (PRP group) included 20 patients with a mean age of 39.10±11.24 years. VAS and median nerve sensory conduction velocity were significantly reduced in group II compared to group I. Conclusions: PRP single local injection in the wrist proved to be better than corticosteroids single local injection for managing mild idiopathic CTS.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140757458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinicians Burnout and Career Satisfaction across The Major Specialties in Zagazig University Hospitals 萨加齐格大学医院各主要专科临床医生的职业倦怠和职业满意度
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.348713
Eman Elshahat, Elsayed Orabi
Background: Burnout is recognized as a prevalent problem in contemporary society, particularly in the realm of occupational stress, and it is garnering global attention. It is identified by a sense of depleted energy, cynicism towards one's job, and diminished professional effectiveness. The level of career satisfaction serves as a crucial indicator of the quality of the healthcare system. Objective: To evaluate the correlation between clinician burnout and career satisfaction in Zagazig University Hospitals, aiming to contribute insights for the enhancement of their overall well-being in future endeavors. Subjects and Methods: A cross-sectional study was conducted on 246 clinicians representing various major specialties at Zagazig University Hospitals from July to November 2023. The used structured questionnaire comprised three parts: 1) Personal and professional characteristics, 2) Maslach Burnout Inventory (MBI) questionnaire, and 3) Career Satisfaction assessment questionnaire. Results: Clinicians exhibited moderate levels of emotional exhaustion (EE), depersonalization (DP), personal accomplishment (PA), and average career satisfaction with percentages of 45.6%, 54.1%, 40.7%, and 43.5%, respectively. Pediatricians demonstrated a significantly higher risk of EE (30.02±7.1), whereas internists were notably at a higher risk of low PA (34.3±10). A significant weak negative correlation was observed between emotional exhaustion and career satisfaction (r= -0.133). Conclusions: A moderate level of burnout syndrome was identified among clinicians in Zagazig University Hospitals. Pediatricians faced a higher risk of emotional exhaustion (EE), while internists were more susceptible to low personal accomplishment (PA). Additionally, an overall average level of career satisfaction and a negative correlation between EE and career satisfaction were observed.
背景:职业倦怠被认为是当代社会的一个普遍问题,尤其是在职业压力领域,它正引起全球的关注。倦怠感表现为精力耗尽、对工作愤世嫉俗以及专业效率降低。职业满意度是衡量医疗保健系统质量的重要指标。目的评估扎加齐格大学医院临床医生职业倦怠与职业满意度之间的相关性,旨在为提高他们在未来工作中的整体福祉提供见解。研究对象和方法:2023 年 7 月至 11 月期间,对代表扎加齐格大学医院各主要专科的 246 名临床医生进行了横断面研究。所使用的结构化问卷包括三个部分:1)个人和职业特征;2)马斯拉奇职业倦怠量表(MBI)问卷;3)职业满意度评估问卷。结果显示临床医生表现出中等程度的情感衰竭(EE)、人格解体(DP)、个人成就感(PA)和平均职业满意度,百分比分别为 45.6%、54.1%、40.7% 和 43.5%。儿科医生的 EE 风险明显更高(30.02±7.1),而内科医生的低 PA 风险明显更高(34.3±10)。情绪衰竭与职业满意度之间存在明显的弱负相关(r= -0.133)。结论是在扎加齐格大学医院的临床医生中发现了中等程度的职业倦怠综合征。儿科医生面临情绪衰竭(EE)的风险较高,而内科医生则更容易出现个人成就感低(PA)的情况。此外,还观察到职业满意度总体处于平均水平,EE 与职业满意度之间呈负相关。
{"title":"Clinicians Burnout and Career Satisfaction across The Major Specialties in Zagazig University Hospitals","authors":"Eman Elshahat, Elsayed Orabi","doi":"10.21608/ejhm.2024.348713","DOIUrl":"https://doi.org/10.21608/ejhm.2024.348713","url":null,"abstract":"Background: Burnout is recognized as a prevalent problem in contemporary society, particularly in the realm of occupational stress, and it is garnering global attention. It is identified by a sense of depleted energy, cynicism towards one's job, and diminished professional effectiveness. The level of career satisfaction serves as a crucial indicator of the quality of the healthcare system. Objective: To evaluate the correlation between clinician burnout and career satisfaction in Zagazig University Hospitals, aiming to contribute insights for the enhancement of their overall well-being in future endeavors. Subjects and Methods: A cross-sectional study was conducted on 246 clinicians representing various major specialties at Zagazig University Hospitals from July to November 2023. The used structured questionnaire comprised three parts: 1) Personal and professional characteristics, 2) Maslach Burnout Inventory (MBI) questionnaire, and 3) Career Satisfaction assessment questionnaire. Results: Clinicians exhibited moderate levels of emotional exhaustion (EE), depersonalization (DP), personal accomplishment (PA), and average career satisfaction with percentages of 45.6%, 54.1%, 40.7%, and 43.5%, respectively. Pediatricians demonstrated a significantly higher risk of EE (30.02±7.1), whereas internists were notably at a higher risk of low PA (34.3±10). A significant weak negative correlation was observed between emotional exhaustion and career satisfaction (r= -0.133). Conclusions: A moderate level of burnout syndrome was identified among clinicians in Zagazig University Hospitals. Pediatricians faced a higher risk of emotional exhaustion (EE), while internists were more susceptible to low personal accomplishment (PA). Additionally, an overall average level of career satisfaction and a negative correlation between EE and career satisfaction were observed.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140764789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Incidence and Outcome of Hypocalcaemia after Total Thyroidectomy 全甲状腺切除术后低钙血症的发生率和结果
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.349392
Naser A. Zaher, Emad M. Abdelrahman, Atef A. Salem, Mohamed M. Debes, Marwa M. Yosry, Mohamed E. Zayed
Background: Due to its prevalence and the absence of well-established preoperative indicators, hypoparathyroidism poses a significant problem. Objective: This study aimed to find characteristics that predict hypocalcemia after total thyroidectomy was the primary goal of this investigation. Patients and methods: In this prospective analysis, 123 patients who were candidates for a thyroidectomy were enrolled. Early hypocalcemia symptoms and potential risk factors were monitored in these individuals. Results: The mean age of the studied patients was 47.22 ± 12.2 years. Hypocalcemia was significantly evident in the age group between 40-50 years. Results showed that recurring goiter, Grave's disease, malignant goiter and block neck dissection were significantly correlated with postoperative hypocalcemia. Conclusion: Malignant goiter, Grave’s disease (GD) and recurrent goiter are independent risk factors for post total thyroidectomy hypocalcemia.
背景:由于甲状旁腺功能减退症发病率高,且缺乏完善的术前指标,因此是一个严重的问题。研究目的本研究的主要目的是找出甲状腺全切除术后预测低钙血症的特征。患者和方法在这项前瞻性分析中,共纳入了 123 名甲状腺切除术候选患者。对这些患者的早期低钙血症症状和潜在风险因素进行了监测。研究结果研究对象的平均年龄为 47.22 ± 12.2 岁。低钙血症在 40-50 岁年龄组明显。结果显示,复发性甲状腺肿、格拉夫病、恶性甲状腺肿和阻滞性颈部切除术与术后低钙血症有显著相关性。结论恶性甲状腺肿、格拉夫病(GD)和复发性甲状腺肿是导致全甲状腺切除术后低钙血症的独立危险因素。
{"title":"Incidence and Outcome of Hypocalcaemia after Total Thyroidectomy","authors":"Naser A. Zaher, Emad M. Abdelrahman, Atef A. Salem, Mohamed M. Debes, Marwa M. Yosry, Mohamed E. Zayed","doi":"10.21608/ejhm.2024.349392","DOIUrl":"https://doi.org/10.21608/ejhm.2024.349392","url":null,"abstract":"Background: Due to its prevalence and the absence of well-established preoperative indicators, hypoparathyroidism poses a significant problem. Objective: This study aimed to find characteristics that predict hypocalcemia after total thyroidectomy was the primary goal of this investigation. Patients and methods: In this prospective analysis, 123 patients who were candidates for a thyroidectomy were enrolled. Early hypocalcemia symptoms and potential risk factors were monitored in these individuals. Results: The mean age of the studied patients was 47.22 ± 12.2 years. Hypocalcemia was significantly evident in the age group between 40-50 years. Results showed that recurring goiter, Grave's disease, malignant goiter and block neck dissection were significantly correlated with postoperative hypocalcemia. Conclusion: Malignant goiter, Grave’s disease (GD) and recurrent goiter are independent risk factors for post total thyroidectomy hypocalcemia.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140771131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Characteristics, Outcomes, and Prognosis among Cancer Patients with Acute Kidney Injury: A Single-Center Study at Sohag Cancer Center 急性肾损伤癌症患者的临床特征、疗效和预后:索哈格癌症中心的一项单中心研究
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.348928
Ahmed M. A. Ismail, Mariam A. Naom, B. M. Refaie, Nesma Magdy, Sahar A. Allam, Ahmed M. Elhalwagy
Background: Acute kidney injury (AKI) is a frequently occurring complication in patients with cancer that can arise from cancer, its treatment, or other complications. Objective: This study aimed to evaluate the epidemiological and clinical characteristics and outcomes of AKI among cancer patients in Egypt. Patients and Methods: This study was conducted at the Intermediate Care Unit (ICU) of Sohag Oncology Center, Sohag, Egypt. This was a retrospective study of 80 cancer patients diagnosed with AKI and admitted to the ICU with AKI between September 2022 and June 2023. Results: The median age of the participants was 58 years. Approximately 52% were females, 95% were diagnosed with solid tumors, and 57% received chemotherapy. According to the RIFLE criteria, 59% of the participants were classified as "Failure", 36% as "Injury", and 5% as "Risk". Approximately 66% of the patients presented with normal consciousness, 82% with repeated vomiting, 99% with fatigue and anorexia, and 88% with hypovolemia. The serum creatinine (SCr) concentration, urea concentration, and international normalized ratio (INR) significantly decreased from presentation to discharge (Pvalue <0.001, <0.001, and 0.031, respectively). However, sodium, potassium, and calcium levels and the glomerular filtration rate (GFR) significantly increased (P=0.004, 0.011, <0.001, and <0.001, respectively). Here, 68% of patients were discharged without the need for dialysis, 18% needed dialysis, and 14% died. Disturbed consciousness (OR=0.14; p = 0.003) and hypovolemia (OR=0.49; p = 0.001) were found to be independent predictors of participant improvement. Conclusion : AKI was more prevalent among elderly females with solid tumors. Common symptoms at presentation were vomiting, fatigue, anorexia, electrolyte imbalances, and hypovolemia. However, additional research is needed to determine the impact of AKI on cancer outcomes.
背景:急性肾损伤(AKI)是癌症患者经常出现的一种并发症,可由癌症、癌症治疗或其他并发症引起。研究目的本研究旨在评估埃及癌症患者急性肾损伤的流行病学和临床特征及结果。患者和方法:本研究在埃及 Sohag 市 Sohag 肿瘤中心的重症监护室 (ICU) 进行。这是一项回顾性研究,研究对象是 2022 年 9 月至 2023 年 6 月期间被诊断为 AKI 并入住重症监护室的 80 名癌症患者。研究结果参与者的中位年龄为 58 岁。约52%为女性,95%被诊断为实体瘤,57%接受了化疗。根据 RIFLE 标准,59% 的参与者被归类为 "失败",36% 被归类为 "损伤",5% 被归类为 "风险"。约 66% 的患者意识正常,82% 的患者反复呕吐,99% 的患者乏力和厌食,88% 的患者血容量不足。从发病到出院,血清肌酐(SCr)浓度、尿素浓度和国际标准化比值(INR)明显下降(P值分别为<0.001、<0.001和0.031)。然而,钠、钾和钙水平以及肾小球滤过率(GFR)却明显升高(P 值分别为 0.004、0.011、<0.001 和 <0.001)。其中,68%的患者出院时无需透析,18%的患者需要透析,14%的患者死亡。研究发现,意识障碍(OR=0.14;P=0.003)和低血容量(OR=0.49;P=0.001)是影响参与者病情改善的独立预测因素。结论:AKI 在患有实体瘤的老年女性中更为普遍。发病时的常见症状包括呕吐、乏力、厌食、电解质失衡和低血容量。不过,还需要进行更多研究,以确定 AKI 对癌症预后的影响。
{"title":"Clinical Characteristics, Outcomes, and Prognosis among Cancer Patients with Acute Kidney Injury: A Single-Center Study at Sohag Cancer Center","authors":"Ahmed M. A. Ismail, Mariam A. Naom, B. M. Refaie, Nesma Magdy, Sahar A. Allam, Ahmed M. Elhalwagy","doi":"10.21608/ejhm.2024.348928","DOIUrl":"https://doi.org/10.21608/ejhm.2024.348928","url":null,"abstract":"Background: Acute kidney injury (AKI) is a frequently occurring complication in patients with cancer that can arise from cancer, its treatment, or other complications. Objective: This study aimed to evaluate the epidemiological and clinical characteristics and outcomes of AKI among cancer patients in Egypt. Patients and Methods: This study was conducted at the Intermediate Care Unit (ICU) of Sohag Oncology Center, Sohag, Egypt. This was a retrospective study of 80 cancer patients diagnosed with AKI and admitted to the ICU with AKI between September 2022 and June 2023. Results: The median age of the participants was 58 years. Approximately 52% were females, 95% were diagnosed with solid tumors, and 57% received chemotherapy. According to the RIFLE criteria, 59% of the participants were classified as \"Failure\", 36% as \"Injury\", and 5% as \"Risk\". Approximately 66% of the patients presented with normal consciousness, 82% with repeated vomiting, 99% with fatigue and anorexia, and 88% with hypovolemia. The serum creatinine (SCr) concentration, urea concentration, and international normalized ratio (INR) significantly decreased from presentation to discharge (Pvalue <0.001, <0.001, and 0.031, respectively). However, sodium, potassium, and calcium levels and the glomerular filtration rate (GFR) significantly increased (P=0.004, 0.011, <0.001, and <0.001, respectively). Here, 68% of patients were discharged without the need for dialysis, 18% needed dialysis, and 14% died. Disturbed consciousness (OR=0.14; p = 0.003) and hypovolemia (OR=0.49; p = 0.001) were found to be independent predictors of participant improvement. Conclusion : AKI was more prevalent among elderly females with solid tumors. Common symptoms at presentation were vomiting, fatigue, anorexia, electrolyte imbalances, and hypovolemia. However, additional research is needed to determine the impact of AKI on cancer outcomes.","PeriodicalId":22467,"journal":{"name":"The Egyptian Journal of Hospital Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140784698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Modified Furlow Vs Two-Flap Technique on Eustachian Tube Function 改良 Furlow 与双瓣技术对咽鼓管功能的影响
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.348718
Mahmoud Sobhy Allam, Samir Ahmed Abdelmaged, Mamdouh M. Aboulhassan, Kamal A. Hassa Hassaneinen, Islam A. Amer
Background: One of the most common congenital defects of the face is cleft palate (CP). A middle ear issue nearly always affects children who have cleft palates. The way that palatoplasty is performed has a significant impact on how well middle ear function is restored after CP correction. Objective: This study aimed to assess the significance of modified Furlow vs two-flaps technique on Eustachian tube (ET) dysfunction. Patients and methods: Seventy two cleft palate patients were divided into 2 groups: Group1 included 42 patients done by modified Furlow Z-plasty operation. Group 2 included 30 patients done by two flaps palatoplasty. Pre-and post-operative ear evaluation done at 1, 3,6,12 months. Results: Repair of cleft palate leading to direct improvement of ET dysfunction improvement ear function. Modified Furlow showed early improvement at 3 months post-operative of middle ear function (p value 0.004), but had no superiority after one year over two flaps Palato-plasty. Conclusion: The two procedures showed significant effect as regards decreasing severity of ET function and middle ear affection. Thus, supporting conservative management of middle ear effusion instead of prophylactic tube insertion.
背景:腭裂(CP)是面部最常见的先天性缺陷之一。患有腭裂的儿童几乎都会出现中耳问题。腭成形术的方式对 CP 矫正后中耳功能的恢复有很大影响。研究目的本研究旨在评估改良 Furlow 与双瓣技术对咽鼓管(ET)功能障碍的影响。患者和方法:72名腭裂患者分为两组:第一组包括 42 名采用改良 Furlow Z 形成形术的患者。第二组包括 30 名采用双瓣腭成形术的患者。术前和术后 1、3、6、12 个月进行耳部评估。结果腭裂修复术可直接改善 ET 功能障碍,改善耳功能。改良 Furlow 显示,术后 3 个月中耳功能得到早期改善(P 值为 0.004),但一年后与双瓣腭成形术相比没有优势。结论:这两种手术在降低 ET 功能和中耳炎的严重程度方面效果明显。因此,支持保守治疗中耳积液,而不是预防性插管。
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引用次数: 0
Effect of Local Dexamethasone on Prevention of Myringosclerosis after Tympanostomy Tube 局部地塞米松对预防鼓室造口术置管后耳硬化症的影响
Pub Date : 2024-04-01 DOI: 10.21608/ejhm.2024.348396
Hossam El Din, M. Azim, M. A. Mahmoud, M. G. Sobhy
Background: Otitis media with effusion, a typical condition characterized by fluid in the middle ear area, has a significant negative influence on both the health and economy of the entire world. In children, hearing loss brought on by otitis media with effusion can hinder the development of language and conduct. This study aimed to assess how local dexamethasone affects human tympanic membranes' ability to resist myringosclerosis brought on by ventilation tubes. Patients and Methods: This prospective case-control study was conducted at Benha University Hospital, on 50 patients of both sexes and different ages complained of hearing loss due to persistent otitis media with effusion that has been resistant to therapy for nearly three months. The patients were subdivided into two equal groups: 25 patients were participants in group (A), which underwent myringotomy with breathing tube insertion only. 25 patients were participants in group (B), who had myringotomy, breathing tube insertion, and local dexamethasone instillation. Results : As far as myringosclerosis was concerned, there was no statistically significant variation between the two groups (P-value > 0.05). As determined by the quadrants under otomicroscopic examination, there was a significant variation between the two groups (P-value < 0.01) in relation to myringosclerosis findings. The histopathological assessment of myringosclerosis revealed a significant variation between the two groups with regard to the condition's symptoms (P-value < 0.01). Conclusion:
背景:中耳炎伴渗出液是一种典型的中耳积液病症,对全世界的健康和经济都有着重大的负面影响。在儿童中,中耳炎伴渗出物导致的听力损失会阻碍语言和行为的发展。本研究旨在评估局部地塞米松如何影响人体鼓膜抵抗通气管引起的髓鞘硬化的能力。患者和方法:这项前瞻性病例对照研究是在本哈大学医院进行的,研究对象是 50 名因顽固性中耳炎伴渗出物而听力下降的患者,他们来自不同性别和年龄,且已抗药近三个月。这些患者被细分为两个相同的小组:25 名患者被分为(A)组,他们只接受了插入呼吸管的耳环切开术。B 组 25 名患者接受了耳膜切开术、插入呼吸管和局部地塞米松注射。结果:就耳膜硬化而言,两组患者的差异无统计学意义(P 值 > 0.05)。根据耳显微镜下的象限判断,两组患者在耳膜硬化症方面存在显著差异(P 值小于 0.01)。对耳膜硬化的组织病理学评估显示,两组患者在耳膜硬化症状方面存在显著差异(P 值 < 0.01)。结论
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The Egyptian Journal of Hospital Medicine
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