Pub Date : 2023-07-01DOI: 10.21608/ejmm.2023.310119
Abeer K. Abu-El-Azayem, R. Dwedar, N. Nashaat, R. Shash
ABSTRACT
摘要
{"title":"Comparative Evaluation of Colistin Susceptibility Testing Using Agar Dilution and Broth Microdilution in Multidrug-resistant and Extensively Drug-resistant Gram-Negative Isolates","authors":"Abeer K. Abu-El-Azayem, R. Dwedar, N. Nashaat, R. Shash","doi":"10.21608/ejmm.2023.310119","DOIUrl":"https://doi.org/10.21608/ejmm.2023.310119","url":null,"abstract":"ABSTRACT","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81795008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular Detection of Human Norovirus among Children (0-5 Years) Attending Selected Hospitals in Kano Metropolis, Kano State, Nigeria","authors":"Nusaiba Kabir Abubakar, Taysir Abdelrahman, Auwal Idris Kabuga, Lawal Dahiru Rogo","doi":"10.21608/ejmm.2023.307443","DOIUrl":"https://doi.org/10.21608/ejmm.2023.307443","url":null,"abstract":"ABSTRACT","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88000131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Usage of Trifluoperazine Hydrochloride as Colorimetric Reagent for Quantitative Assay of Sulfamethoxazole Drug and Applications on Different Some Infection Treatment Preparations","authors":"Haydar S.M. AL-Hujaimi, Mohauman AL- Rufaie, Zahraa M.M. Alrufaie","doi":"10.21608/ejm.2023.181202.1223","DOIUrl":"https://doi.org/10.21608/ejm.2023.181202.1223","url":null,"abstract":"","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"137 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76186596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.21608/ejmm.2023.291146
M. Gaafar, Mariam Balah, Hebatallah A. Kassem, H. Sabry, Reem ElMessiery, N. Soliman
{"title":"Random SARS-CoV-2 antibody screening in Egypt during the COVID-19 third wave","authors":"M. Gaafar, Mariam Balah, Hebatallah A. Kassem, H. Sabry, Reem ElMessiery, N. Soliman","doi":"10.21608/ejmm.2023.291146","DOIUrl":"https://doi.org/10.21608/ejmm.2023.291146","url":null,"abstract":"","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"517 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77147207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.21608/ejmm.2023.293577
{"title":"Candidaemia in Neonatal Intensive Care Units (NICU) at Beni-Suef Governorate","authors":"","doi":"10.21608/ejmm.2023.293577","DOIUrl":"https://doi.org/10.21608/ejmm.2023.293577","url":null,"abstract":"","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80713011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.21608/ejmm.2023.279741
Rehab Bahy, Wael Mohamed Abu El-Wafa, A. Abouwarda
ABSTRACT
摘要
{"title":"Molecular Mechanisms of Fosfomycin Resistance in MDR Escherichia coli Isolates from Urinary Tract Infections","authors":"Rehab Bahy, Wael Mohamed Abu El-Wafa, A. Abouwarda","doi":"10.21608/ejmm.2023.279741","DOIUrl":"https://doi.org/10.21608/ejmm.2023.279741","url":null,"abstract":"ABSTRACT","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89815752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.21608/ejmm.2023.281033
S. Fouad, M. Farris, Eman R. Mansour, Mayada Moneer
Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune multisystem disease with an array of variable presentations in which the kidney is the most affected organ and influences the overall outcome of the patients. Methodology: The study is a case control study conducted on 90 SLE patients diagnosed according to ACR criteria grouped into three subgroups. It aims at evaluating the role of serum tumor necrosis factor alpha (TNFα), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in diagnosing renal flares and predicting the prognosis in lupus nephritis patients. Results: A highly significant difference was observed between both the SLE starting dialysis group, the SLE nephritis ( LN ) group, and the control group regarding neutrophil to lymphocyte ratio and TNFα (p<0.001 & ˂ 0.001, respectively). The median serum Neutrophil/Lymphocyte and TNFα were statistically significantly higher in the SLE starting dialysis patient group than the LN patients and the control group. A cut-off value of ≤ 200 for serum TNFα level and of ≤ 4.8 for Neutrophil/lymphocyte ratio sufficiently differentiated between the LN patients and the SLE patients starting dialysis. TNFα cut-off value showed sensitivity of 76.67%, specificity of 96.67%, positive predictive value of 95.8% and negative predictive value of 80.6 %. Neutrophil/Lymphocyte cut-off showed sensitivity of 70.00%, specificity of 70.00%, positive predictive value of 70.00% and negative predictive value of 70.00 %. Conclusion: NLR and TNFα serum levels appear to be useful biomarkers for disease flares and tissue injury in LN patients. Both can identify disease activities, relapses and remissions in lupus nephritis patients.
{"title":"Can Neutrophil to Lymphocyte Ratio, Platelet to Lymphocyte Ratio and Tumor Necrosis Factor Alpha Predict Lupus Nephritis Flares?","authors":"S. Fouad, M. Farris, Eman R. Mansour, Mayada Moneer","doi":"10.21608/ejmm.2023.281033","DOIUrl":"https://doi.org/10.21608/ejmm.2023.281033","url":null,"abstract":"Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune multisystem disease with an array of variable presentations in which the kidney is the most affected organ and influences the overall outcome of the patients. Methodology: The study is a case control study conducted on 90 SLE patients diagnosed according to ACR criteria grouped into three subgroups. It aims at evaluating the role of serum tumor necrosis factor alpha (TNFα), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in diagnosing renal flares and predicting the prognosis in lupus nephritis patients. Results: A highly significant difference was observed between both the SLE starting dialysis group, the SLE nephritis ( LN ) group, and the control group regarding neutrophil to lymphocyte ratio and TNFα (p<0.001 & ˂ 0.001, respectively). The median serum Neutrophil/Lymphocyte and TNFα were statistically significantly higher in the SLE starting dialysis patient group than the LN patients and the control group. A cut-off value of ≤ 200 for serum TNFα level and of ≤ 4.8 for Neutrophil/lymphocyte ratio sufficiently differentiated between the LN patients and the SLE patients starting dialysis. TNFα cut-off value showed sensitivity of 76.67%, specificity of 96.67%, positive predictive value of 95.8% and negative predictive value of 80.6 %. Neutrophil/Lymphocyte cut-off showed sensitivity of 70.00%, specificity of 70.00%, positive predictive value of 70.00% and negative predictive value of 70.00 %. Conclusion: NLR and TNFα serum levels appear to be useful biomarkers for disease flares and tissue injury in LN patients. Both can identify disease activities, relapses and remissions in lupus nephritis patients.","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"12 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79485764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.21608/ejmm.2023.280275
R. Khalifa, Nesma Abdel Aziz, A. Shalash, M. Nada, Shimaa A. Abdel Salam
ABSTRACT
摘要
{"title":"IL-23 Receptor Expression on T Helper 17 Cells and its Implication in Multiple Sclerosis Relapse","authors":"R. Khalifa, Nesma Abdel Aziz, A. Shalash, M. Nada, Shimaa A. Abdel Salam","doi":"10.21608/ejmm.2023.280275","DOIUrl":"https://doi.org/10.21608/ejmm.2023.280275","url":null,"abstract":"ABSTRACT","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84327897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.21608/ejmm.2023.285582
Ahmed G. Merdash, G. El-Sherbiny, A. Elgendy, M. Ahmad, H. El-Kabbany
Background: Urinary tract infections (UTIs) are one of the most common bacterial infections which affect more than 150 million individuals each year worldwide. Objective : this study was conducted to assess the risk factors associated with urinary tract infections (UTIs) caused by resistant Escherichia coli. Methodology Four hundred and thirty urine samples were collected from outpatients who had urinary tract symptoms, ages ranging from 10 to 75 years in Beni-Suef Egypt, during a period extended from January 2021 to the end January 2022 and processed by standard microbiological methods. Results A total of 430 patients were included in this study: 210 (48.82%) uncomplicated and 220 (51.15%) complicated UTIs. Of 430 UTIs patients 287(66.8%) were females (77(36.6%) were complicated and 210(100%) were uncomplicated), while 143 male UTIs patients were classified as complicated (65%). The prevalence of pathogenic microbes reveals bacterial species predominate in UTIs with 376 (87.42%) E. coli high-frequency bacterial strains 85 (19.9%), followed by Klebsiella sp. 70 (16.3), Pseudomonas aeruginosa 58 (13.5%) and Enterococcus sp. 58 (13.5%). Proteus mirabilis 46(10.9%). Among 85 E coli isolates 46 from complicated and 39 isolates from uncomplicated UTIs patients showed the highest resistance to piperacillin/tazobactam 35(41.2%), sulfamethoxazole /trimethoprim 35 (41.2%), amoxicillin-clavulanic acid 34 (40%) and cefepime 34 (40%) and the least resistant antibiotics in the present study were colistin (3.5%), imipenem (5%), quinolones (5%) and nitrofurantoin (5%). Conclusion , nitrofurantoin, and quinoline remain still the best choice for treating complicated and uncomplicated UTI. Risk increases with the number of patients hospitalizations.
{"title":"The Relation between Antibiotic Resistance pattern and the Risk Factors Associated with Urinary Tract Infections Caused by E. coli.","authors":"Ahmed G. Merdash, G. El-Sherbiny, A. Elgendy, M. Ahmad, H. El-Kabbany","doi":"10.21608/ejmm.2023.285582","DOIUrl":"https://doi.org/10.21608/ejmm.2023.285582","url":null,"abstract":"Background: Urinary tract infections (UTIs) are one of the most common bacterial infections which affect more than 150 million individuals each year worldwide. Objective : this study was conducted to assess the risk factors associated with urinary tract infections (UTIs) caused by resistant Escherichia coli. Methodology Four hundred and thirty urine samples were collected from outpatients who had urinary tract symptoms, ages ranging from 10 to 75 years in Beni-Suef Egypt, during a period extended from January 2021 to the end January 2022 and processed by standard microbiological methods. Results A total of 430 patients were included in this study: 210 (48.82%) uncomplicated and 220 (51.15%) complicated UTIs. Of 430 UTIs patients 287(66.8%) were females (77(36.6%) were complicated and 210(100%) were uncomplicated), while 143 male UTIs patients were classified as complicated (65%). The prevalence of pathogenic microbes reveals bacterial species predominate in UTIs with 376 (87.42%) E. coli high-frequency bacterial strains 85 (19.9%), followed by Klebsiella sp. 70 (16.3), Pseudomonas aeruginosa 58 (13.5%) and Enterococcus sp. 58 (13.5%). Proteus mirabilis 46(10.9%). Among 85 E coli isolates 46 from complicated and 39 isolates from uncomplicated UTIs patients showed the highest resistance to piperacillin/tazobactam 35(41.2%), sulfamethoxazole /trimethoprim 35 (41.2%), amoxicillin-clavulanic acid 34 (40%) and cefepime 34 (40%) and the least resistant antibiotics in the present study were colistin (3.5%), imipenem (5%), quinolones (5%) and nitrofurantoin (5%). Conclusion , nitrofurantoin, and quinoline remain still the best choice for treating complicated and uncomplicated UTI. Risk increases with the number of patients hospitalizations.","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78236075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.21608/ejmm.2023.287944
Sami S. Ashgar, Bashair Alharthi, Hamdi M. Al-Said, Naif A. Jalal, A. Momenah, A. Barhameen, S. Hariri, Farkad Bantun, E. Khidir, Asim Abdulshakoor, Batool J Alghamdi, Rahf Albarakati
{"title":"Prevalence of Enteric Pathogens in the Prepackaged Salads in Makkah City, Saudi Arabia","authors":"Sami S. Ashgar, Bashair Alharthi, Hamdi M. Al-Said, Naif A. Jalal, A. Momenah, A. Barhameen, S. Hariri, Farkad Bantun, E. Khidir, Asim Abdulshakoor, Batool J Alghamdi, Rahf Albarakati","doi":"10.21608/ejmm.2023.287944","DOIUrl":"https://doi.org/10.21608/ejmm.2023.287944","url":null,"abstract":"","PeriodicalId":22549,"journal":{"name":"The Egyptian Journal of Medical Microbiology","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79088479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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