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Impact of Procurement Methods on Organ Rejection in Donation After Circulatory Death Heart Transplantation. 在循环死亡后心脏移植手术中,采购方法对器官排斥反应的影响。
Pub Date : 2024-10-20 DOI: 10.1016/j.healun.2024.10.015
Ye In Christopher Kwon,Elizabeth Bashian,Arman Kilic,Zubair A Hashmi
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引用次数: 0
Sympathetic reinnervation in cardiac transplant recipients: Prevalence, time course and association with long-term survival. 心脏移植受者的交感神经再支配:发病率、时间过程以及与长期存活的关系。
Pub Date : 2024-10-18 DOI: 10.1016/j.healun.2024.10.009
Oliver J F Weiner,Moloy Das,Richard H Clayton,Janet M McComb,Alan Murray,Gareth Parry,Stephen W Lord
BACKGROUNDPartial cardiac sympathetic reinnervation after cardiac transplant has been extensively investigated and evidenced. However, there have been no large-scale, long-term studies evaluating the prevalence, time-course, and association with long-term survival of sympathetic reinnervation of the heart.METHODSCardiac transplant recipients (n=232) were recruited from outpatient clinic at a single transplant centre in the United Kingdom. Participants were each tested once for the presence of sympathetic reinnervation of the sinus node using the low frequency component of power spectral analysis of heart rate variability, with a cut-off defined as 2 standard deviations above the mean for denervated participants (those tested <56 days post-transplant). Time-course was calculated based on the timing of testing post-transplant. Patients were then followed-up over a period of up to 27 years after transplant for survival analysis.RESULTSThe overall prevalence of cardiac sympathetic reinnervation in the 225 patients tested >56 days post-transplant was 64.9%. Sympathetic reinnervation primarily occurred in the first 18 months after transplant, with a plateau thereafter. The prevalence in participants tested >18 months post-transplant was 69.6%. In Kaplan-Meier survival analysis, sympathetic reinnervation was associated with significantly improved survival (Log-rank P=0.019), with a median survival time for reinnervated patients of 19.9 years compared to 14.4 years for the denervated group.CONCLUSIONSSympathetic reinnervation of the sinus node occurs mostly within 18 months of transplant, is found in 70% of cardiac transplant recipients tested >18 months post-transplant, and is associated with significantly improved long-term survival.
背景心脏移植后部分心脏交感神经再支配已得到广泛的研究和证实。方法从英国一家移植中心的门诊招募心脏移植受者(232 人)。利用心率变异性功率谱分析的低频分量对每位受试者进行了一次窦房结交感神经再支配的检测,对去神经支配的受试者的临界值定义为高于平均值 2 个标准差(移植后 56 天的受试者为 64.9%)。交感神经再支配主要发生在移植后的头 18 个月,此后趋于平稳。在移植后 18 个月以上接受测试的参与者中,这一比例为 69.6%。在 Kaplan-Meier 生存分析中,交感神经再支配与生存率的显著提高有关(Log-rank P=0.019),再支配患者的中位生存时间为 19.9 年,而去神经支配组为 14.4 年。
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引用次数: 0
Bridging Gaps in Lung Allocation: A Data-Driven Approach to Overcome Biological Disparities. 缩小肺分配差距:用数据驱动的方法克服生物差异。
Pub Date : 2024-10-18 DOI: 10.1016/j.healun.2024.10.008
Ankit Bharat
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引用次数: 0
Severe primary graft dysfunction after heart transplantation - Defining the Subtypes. 心脏移植后严重的原发性移植物功能障碍--亚型的定义。
Pub Date : 2024-10-18 DOI: 10.1016/j.healun.2024.10.010
Sanjay Dutta,Peter S Macdonald
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引用次数: 0
Pathologist Interrater Reliability and Clinical Implications of Elevated Donor-Derived Cell-Free DNA beyond Heart Transplant Rejection. 病理学家的互斥可靠性和供体来源细胞游离 DNA 升高超出心脏移植排斥反应的临床意义。
Pub Date : 2024-10-16 DOI: 10.1016/j.healun.2024.10.006
Aditya Mehta,Jason Goldberg,Pramita Bagchi,Charles Marboe,Keyur B Shah,Samer S Najjar,Steven Hsu,Maria E Rodrigo,Moon Kyoo Jang,Adam Cochrane,Inna F Tchoukina,Hyesik Kong,Brendan J Lohmar,Erick Mcnair,Hannah A Valantine,Sean Agbor-Enoh,Gerald J Berry,Palak Shah,
BACKGROUNDThere is significant variability amongst pathologists in the histopathological interpretation of the endomyocardial biopsy (EMB) for acute cellular rejection (ACR) and assessment of variability in the interpretation of antibody-mediated rejection (AMR) has not been reported. In contemporary practice, the strategy of allograft surveillance with donor-derived cell-free DNA (dd-cfDNA) as compared to EMB has not been compared with a focus on long-term clinical outcomes beyond acute rejection (AR).METHODSThe Genomic Research Alliance for Transplantation (GRAfT) is a multicenter, prospective cohort study that enrolled patients from 2015 to 2020. The center pathologist read was compared to two blinded core cardiac pathologists. ACR and AMR were graded based on the International Society for Heart and Lung Transplantation (ISHLT) criteria. Weighted Cohen's kappa (κ) was used to evaluate interrater reliability between the center and core reads. To assess long-term outcomes, we evaluated a composite of AR, allograft dysfunction, and mortality within 1 year.RESULTSThe study included 94 patients (median age 55 years [IQR 45, 62]), 30% female, 41% Black race) with a total of 429 EMBs and paired dd-cfDNA measures. The concordance rate between center and core pathologists was 77% for ACR (95%CI: 66% - 89%) and 63% for AMR (95%CI: 53% - 74%). 46 patients had an elevation in dd-cfDNA without AR by EMB. The median dd-cfDNA was 0.49% (IQR: 0.35, 1.01) and subsequent AR, allograft dysfunction, or mortality occurred in 59% of these patients at 1 year. In patients with AR by EMB and negative dd-cfDNA (n=5) the composite outcome occurred in 20% of patients at 1 year. At baseline, the positive likelihood ratio (LR+) of dd-cfDNA to detect AR by the center pathologist was 3.74 (95% CI 3.01 - 4.64) and core pathologist was 2.59 (95%CI: 1.95 - 3.45). If the composite outcome was included as a true positive, the LR+ of dd-cfDNA improved to 9.82 (95%CI: 7.04, 13.69) and7.63 (95% CI: 5.61, 10.38) at 1-year, respectively.CONCLUSIONSPathologists interrater reliability is limited in both ACR and AMR. The positive LR of dd-cfDNA when compared to traditional histopathology is limited, but when longitudinal clinical outcomes are included to assess diagnostic performance, the LR+ improves significantly. The value of dd-cfDNA extends beyond the diagnosis of AR to include other clinically meaningful outcomes for patients after heart transplant.
背景病理学家对急性细胞排斥反应(ACR)的心内膜活检(EMB)组织病理学解释存在很大差异,而对抗体介导的排斥反应(AMR)解释的差异评估尚未见报道。方法移植基因组研究联盟(GRAfT)是一项多中心、前瞻性队列研究,从 2015 年到 2020 年招募患者。中心病理学家的读片结果与两位盲法核心心脏病理学家的读片结果进行了比较。根据国际心肺移植学会(ISHLT)标准对 ACR 和 AMR 进行分级。加权科恩卡帕(κ)用于评估中心和核心病理读片之间的相互可靠性。为了评估长期结果,我们对 AR、异体移植功能障碍和 1 年内死亡率进行了综合评估。结果该研究纳入了 94 名患者(中位年龄 55 岁 [IQR:45,62],30% 为女性,41% 为黑人),共有 429 个 EMB 和配对 dd-cfDNA 测量值。中心和核心病理学家之间的 ACR 一致率为 77%(95%CI:66% - 89%),AMR 一致率为 63%(95%CI:53% - 74%)。46 例患者的 dd-cfDNA 升高,但 EMB 无 AR。dd-cfDNA 中位数为 0.49%(IQR:0.35,1.01),这些患者中有 59% 在 1 年后出现 AR、异体移植功能障碍或死亡。在通过 EMB 检测出现 AR 且 dd-cfDNA 阴性的患者中(5 人),20% 的患者在 1 年后出现了综合结果。基线时,中心病理学家检测到 AR 的 dd-cfDNA 阳性似然比 (LR+) 为 3.74 (95%CI 3.01 - 4.64),核心病理学家为 2.59 (95%CI: 1.95 - 3.45)。如果将综合结果列为真阳性,1 年后 dd-cfDNA 的 LR+ 分别提高到 9.82 (95%CI: 7.04, 13.69) 和 7.63 (95%CI: 5.61, 10.38)。与传统的组织病理学相比,dd-cfDNA 的阳性 LR 有限,但如果纳入纵向临床结果来评估诊断性能,LR+ 则会显著提高。dd-cfDNA 的价值不仅限于 AR 的诊断,还包括心脏移植后患者的其他有临床意义的结果。
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引用次数: 0
ISHLT consensus statement on the perioperative use of ECLS in lung transplantation: Part II: Intraoperative considerations. ISHLT 关于肺移植围手术期使用 ECLS 的共识声明:第二部分:术中注意事项。
Pub Date : 2024-10-09 DOI: 10.1016/j.healun.2024.08.027
Archer Kilbourne Martin,Olaf Mercier,Ashley Virginia Fritz,Theresa A Gelzinis,Konrad Hoetzenecker,Sandra Lindstedt,Nandor Marczin,Barbara J Wilkey,Marc Schecter,Haifa Lyster,Melissa Sanchez,James Walsh,Orla Morrissey,Bronwyn Levvey,Caroline Landry,Siavosh Saatee,Sakhee Kotecha,Juergen Behr,Jasleen Kukreja,Göran Dellgren,Julien Fessler,Brandi Bottiger,Keith Wille,Kavita Dave,Basil S Nasir,David Gomez-De-Antonio,Marcelo Cypel,Anna K Reed
The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no multidisciplinary consensus document has examined the perioperative considerations of how to best manage these patients. To address this challenge, this perioperative utilization of ECLS in lung transplantation consensus statement was approved for development by the International Society for Heart and Lung Transplantation Standards and Guidelines Committee. International experts across multiple disciplines, including cardiothoracic surgery, anesthesiology, critical care, pediatric pulmonology, adult pulmonology, pharmacy, psychology, physical therapy, nursing, and perfusion, were selected based on expertise and divided into subgroups examining the preoperative, intraoperative, and postoperative periods. Following a comprehensive literature review, each subgroup developed recommendations to examine via a structured Delphi methodology. Following 2 rounds of Delphi consensus, a total of 39 recommendations regarding intraoperative considerations for ECLS in lung transplantation met consensus criteria. These recommendations focus on the planning, implementation, management, and monitoring of ECLS throughout the entire intraoperative period.
在肺移植围手术期使用体外生命支持(ECLS)需要多学科专家组成的综合团队进行细致的规划和执行。迄今为止,还没有一份多学科共识文件对如何最佳管理这些患者的围手术期注意事项进行过研究。为了应对这一挑战,国际心肺移植学会标准和指南委员会批准制定了这份肺移植围手术期使用 ECLS 的共识声明。国际专家来自多个学科,包括心胸外科、麻醉学、重症监护、儿科肺病学、成人肺病学、药学、心理学、理疗学、护理学和灌注学,他们根据专业知识进行筛选,并分成若干个小组,分别对术前、术中和术后进行检查。在进行了全面的文献综述后,各分组通过结构化德尔菲法提出了研究建议。经过两轮德尔菲共识,共有 39 项关于肺移植术中 ECLS 术中注意事项的建议符合共识标准。这些建议重点关注整个术中期间 ECLS 的计划、实施、管理和监控。
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引用次数: 0
Impact of Routine Extracorporeal Cardiopulmonary Resuscitation Service on the Availability of Donor Organs. 常规体外心肺复苏服务对捐赠器官可用性的影响。
Pub Date : 2024-09-16 DOI: 10.1016/j.healun.2024.09.009
Jana Smalcova,Petra Krupickova,Eva Pokorna,Ondrej Franek,Michal Huptych,Petra Kavalkova,Martin Balik,Jan Malik,Ondrej Smid,Eva Svobodova,Roman Keleman,Jan Belohlavek
In refractory cardiac arrest, extracorporeal cardiopulmonary resuscitation may increase the survival chance. However, in cases of unsuccessful treatment, extracorporeal cardiopulmonary resuscitation may additionally provide an important source of organ donors. Therefore, we hypothesized that implementing extracorporeal cardiopulmonary resuscitation service into a high-volume cardiac arrest center's routine would increases organ donors' availability.METHODSOur retrospective observational study analyzed out-of-hospital cardiac arrest patients admitted to the General University Hospital in Prague between 2007 and 2020. The following groups were analyzed regarding the recruitment of donors: before and after extracorporeal cardiopulmonary resuscitation implementation. We assessed the number of donors referred, the number of organs harvested, and the organ's survival.RESULTSWe analyzed the results of 1158 patients after out-of-hospital cardiac arrest. In the conventional approach period, 11 donors were referred, of which seven were accepted. During the extracorporeal cardiopulmonary resuscitation period, the number of donors increased to 80, of whom 42 were accepted. The number of donated organs was 18 and 119 in the respective periods, corresponding to 3.6 vs. 13.2 (p = 0.033) harvested organs per year. One-year survival of transplanted organs was 94.4% vs. 99.2%, and five-year survival was 94.4% vs. 95.9% in relevant periods. Conventional and extracorporeal cardiopulmonary resuscitation did not affect donor organ survival.CONCLUSIONEstablishing a high-volume cardiac arrest centre providing an extracorporeal cardiopulmonary resuscitation service may increase not only the number of prolonged cardiac arrest survivors but also the number of organ donors. In addition, the performances of donated organs were high and comparable between both treatment methods.
对于难治性心脏骤停患者,体外心肺复苏术可增加存活机会。然而,在治疗不成功的情况下,体外心肺复苏还可以提供重要的器官供体来源。因此,我们假设将体外心肺复苏服务纳入大容量心脏骤停中心的日常工作中,将增加器官捐献者的可用性。方法本回顾性观察研究分析了 2007 年至 2020 年期间布拉格综合大学医院收治的院外心脏骤停患者。我们对以下几组患者的供体招募情况进行了分析:实施体外心肺复苏术前和实施体外心肺复苏术后。我们评估了转介的捐献者人数、摘取的器官数量和器官存活率。结果 我们分析了 1158 名院外心脏骤停患者的结果。在传统方法期间,共转介了 11 名捐献者,其中 7 人接受了捐献。在体外心肺复苏期间,捐献者人数增至 80 人,其中 42 人被接受。在这两个时期,捐献器官的数量分别为 18 个和 119 个,相当于每年收获 3.6 个器官和 13.2 个器官(p = 0.033)。移植器官的一年存活率为 94.4% 对 99.2%,五年存活率为 94.4% 对 95.9%。结论建立一个提供体外心肺复苏服务的大容量心脏骤停中心不仅可以增加长期心脏骤停幸存者的数量,还可以增加器官捐献者的数量。此外,两种治疗方法的捐赠器官性能都很高,而且不相上下。
{"title":"Impact of Routine Extracorporeal Cardiopulmonary Resuscitation Service on the Availability of Donor Organs.","authors":"Jana Smalcova,Petra Krupickova,Eva Pokorna,Ondrej Franek,Michal Huptych,Petra Kavalkova,Martin Balik,Jan Malik,Ondrej Smid,Eva Svobodova,Roman Keleman,Jan Belohlavek","doi":"10.1016/j.healun.2024.09.009","DOIUrl":"https://doi.org/10.1016/j.healun.2024.09.009","url":null,"abstract":"In refractory cardiac arrest, extracorporeal cardiopulmonary resuscitation may increase the survival chance. However, in cases of unsuccessful treatment, extracorporeal cardiopulmonary resuscitation may additionally provide an important source of organ donors. Therefore, we hypothesized that implementing extracorporeal cardiopulmonary resuscitation service into a high-volume cardiac arrest center's routine would increases organ donors' availability.METHODSOur retrospective observational study analyzed out-of-hospital cardiac arrest patients admitted to the General University Hospital in Prague between 2007 and 2020. The following groups were analyzed regarding the recruitment of donors: before and after extracorporeal cardiopulmonary resuscitation implementation. We assessed the number of donors referred, the number of organs harvested, and the organ's survival.RESULTSWe analyzed the results of 1158 patients after out-of-hospital cardiac arrest. In the conventional approach period, 11 donors were referred, of which seven were accepted. During the extracorporeal cardiopulmonary resuscitation period, the number of donors increased to 80, of whom 42 were accepted. The number of donated organs was 18 and 119 in the respective periods, corresponding to 3.6 vs. 13.2 (p = 0.033) harvested organs per year. One-year survival of transplanted organs was 94.4% vs. 99.2%, and five-year survival was 94.4% vs. 95.9% in relevant periods. Conventional and extracorporeal cardiopulmonary resuscitation did not affect donor organ survival.CONCLUSIONEstablishing a high-volume cardiac arrest centre providing an extracorporeal cardiopulmonary resuscitation service may increase not only the number of prolonged cardiac arrest survivors but also the number of organ donors. In addition, the performances of donated organs were high and comparable between both treatment methods.","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142246786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The iPeer2Peer mentorship program for adolescent thoracic transplant recipients: An implementation-effectiveness evaluation. 针对青少年胸部移植受者的 iPeer2Peer 导师计划:实施效果评估。
Pub Date : 2024-09-09 DOI: 10.1016/j.healun.2024.09.001
Samantha J Anthony,Jia Lin,Enid K Selkirk,Megan Liang,Faye Ajmera,Mirna Seifert-Hansen,Simon Urschel,Stephanie Soto,Suzanne Boucher,Anna Gold,Jennifer N Stinson,Sara Ahola Kohut
BACKGROUNDAn increase in self-management skills for adolescent thoracic transplant recipients may improve health outcomes and facilitate a successful transition to adulthood. The iPeer2Peer© program is an online peer mentorship program that has been successfully implemented as a self-management intervention in multiple chronic disease populations. This study aimed to determine the implementation and effectiveness outcomes of the iPeer2Peer program for adolescent thoracic transplant recipients.METHODSA type III, hybrid implementation-effectiveness pilot study that comprised a quasi-experimental single-arm pre-post design was used to evaluate the iPeer2Peer program. Participant mentees, ages 12 to 17, were recruited from two large Canadian transplant centres. Peer mentors, ages 18 to 25, were thoracic transplant recipients who had successfully transitioned to adult care and self-manage their condition. A mixed methods approach for data collection was used, including interviews, focus groups, and standardized questionnaires.RESULTSTwenty mentees (median 15.0 years, IQR 3.3 years; 65% female) completed the iPeer2Peer program with nine young adult mentors (median 21.0 years, IQR 3.0 years; 78% female). Implementation outcomes indicated that the iPeer2Peer intervention was perceived as feasible, adoptable, acceptable, and appropriate for adolescent thoracic transplant recipients. Significant findings were noted in mentees for increased self-management and a decrease in overall depression and anxiety symptoms.CONCLUSIONSThe successful implementation of the pilot iPeer2Peer program offers support to evaluate the scalability, sustainability, and cost-effectiveness of the program for adolescents with chronic illness, specifically thoracic transplant recipients. Changes to the iPeer2Peer program that facilitate a flexible delivery may help implementation and acceptance.
背景青少年胸腔移植受者自我管理技能的提高可改善其健康状况,并促进其成功过渡到成年期。iPeer2Peer©计划是一项在线同伴指导计划,已在多种慢性病人群中成功实施,作为自我管理干预措施。本研究旨在确定 iPeer2Peer 计划在青少年胸腔移植受者中的实施情况和效果。方法本研究采用 III 型混合实施效果试点研究(包括准实验性单臂前-后设计)来评估 iPeer2Peer 计划。从加拿大两个大型移植中心招募了 12 至 17 岁的被指导者。朋辈导师的年龄在 18 到 25 岁之间,他们都是胸腔移植受者,已成功过渡到成人护理并能自我管理病情。结果20名被指导者(中位数为15.0岁,IQR为3.3岁;65%为女性)与9名年轻的成年指导者(中位数为21.0岁,IQR为3.0岁;78%为女性)完成了iPeer2Peer项目。实施结果表明,iPeer2Peer 干预被认为是可行的、可采用的、可接受的,并且适合青少年胸腔移植受者。结论iPeer2Peer试点项目的成功实施为评估该项目在青少年慢性病患者(尤其是胸腔移植受者)中的可扩展性、可持续性和成本效益提供了支持。对 "iPeer2Peer "计划进行修改,以便灵活实施,这将有助于计划的实施和被接受。
{"title":"The iPeer2Peer mentorship program for adolescent thoracic transplant recipients: An implementation-effectiveness evaluation.","authors":"Samantha J Anthony,Jia Lin,Enid K Selkirk,Megan Liang,Faye Ajmera,Mirna Seifert-Hansen,Simon Urschel,Stephanie Soto,Suzanne Boucher,Anna Gold,Jennifer N Stinson,Sara Ahola Kohut","doi":"10.1016/j.healun.2024.09.001","DOIUrl":"https://doi.org/10.1016/j.healun.2024.09.001","url":null,"abstract":"BACKGROUNDAn increase in self-management skills for adolescent thoracic transplant recipients may improve health outcomes and facilitate a successful transition to adulthood. The iPeer2Peer© program is an online peer mentorship program that has been successfully implemented as a self-management intervention in multiple chronic disease populations. This study aimed to determine the implementation and effectiveness outcomes of the iPeer2Peer program for adolescent thoracic transplant recipients.METHODSA type III, hybrid implementation-effectiveness pilot study that comprised a quasi-experimental single-arm pre-post design was used to evaluate the iPeer2Peer program. Participant mentees, ages 12 to 17, were recruited from two large Canadian transplant centres. Peer mentors, ages 18 to 25, were thoracic transplant recipients who had successfully transitioned to adult care and self-manage their condition. A mixed methods approach for data collection was used, including interviews, focus groups, and standardized questionnaires.RESULTSTwenty mentees (median 15.0 years, IQR 3.3 years; 65% female) completed the iPeer2Peer program with nine young adult mentors (median 21.0 years, IQR 3.0 years; 78% female). Implementation outcomes indicated that the iPeer2Peer intervention was perceived as feasible, adoptable, acceptable, and appropriate for adolescent thoracic transplant recipients. Significant findings were noted in mentees for increased self-management and a decrease in overall depression and anxiety symptoms.CONCLUSIONSThe successful implementation of the pilot iPeer2Peer program offers support to evaluate the scalability, sustainability, and cost-effectiveness of the program for adolescents with chronic illness, specifically thoracic transplant recipients. Changes to the iPeer2Peer program that facilitate a flexible delivery may help implementation and acceptance.","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142174668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reactivation of Chagas Disease 南美锥虫病复发
Pub Date : 2024-04-01 DOI: 10.1016/j.healun.2024.02.1250
S. Moraes, M. Heringer, G. Campos, L. Xavier, S. Mangini, F. Bacal
{"title":"Reactivation of Chagas Disease","authors":"S. Moraes, M. Heringer, G. Campos, L. Xavier, S. Mangini, F. Bacal","doi":"10.1016/j.healun.2024.02.1250","DOIUrl":"https://doi.org/10.1016/j.healun.2024.02.1250","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"56 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140759327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Natural Outcome of Isolated Right Ventricular Dysfunction Immediately After Heart Transplantation 心脏移植术后即刻出现孤立性右心室功能障碍的自然结果
Pub Date : 2024-04-01 DOI: 10.1016/j.healun.2024.02.687
M. Kittleson, J. Patel, A. Nikolova, M. White, N. Bhatnagar, A. Kanungo, M. Lee, E. Chow, J. Moriguchi, D. Geft, L. Czer, F. Esmailian, J. Kobashigawa
{"title":"Natural Outcome of Isolated Right Ventricular Dysfunction Immediately After Heart Transplantation","authors":"M. Kittleson, J. Patel, A. Nikolova, M. White, N. Bhatnagar, A. Kanungo, M. Lee, E. Chow, J. Moriguchi, D. Geft, L. Czer, F. Esmailian, J. Kobashigawa","doi":"10.1016/j.healun.2024.02.687","DOIUrl":"https://doi.org/10.1016/j.healun.2024.02.687","url":null,"abstract":"","PeriodicalId":22654,"journal":{"name":"The Journal of Heart and Lung Transplantation","volume":"231 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140762337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
The Journal of Heart and Lung Transplantation
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