The Lancet Regional Health: Western Pacific最新文献

{"title":"Socioeconomic disadvantage and polygenic risk of overweight in early and mid-life: a longitudinal population cohort study spanning 12 years","authors":"Jessica A. Kerr ,&nbsp;Dorothea Dumuid ,&nbsp;Marnie Downes ,&nbsp;Katherine Lange ,&nbsp;Meredith O'Connor ,&nbsp;Ty Stanford ,&nbsp;Lukar Thornton ,&nbsp;Suzanne Mavoa ,&nbsp;Kate Lycett ,&nbsp;Tim S. Olds ,&nbsp;Ben Edwards ,&nbsp;Justin O'Sullivan ,&nbsp;Markus Juonala ,&nbsp;Ha N.D. Le ,&nbsp;Richard Saffery ,&nbsp;David Burgner ,&nbsp;Melissa Wake","doi":"10.1016/j.lanwpc.2024.101231","DOIUrl":"10.1016/j.lanwpc.2024.101231","url":null,"abstract":"<div><h3>Background</h3><div>We describe BMI by socioeconomic disadvantage and by polygenic risk in parallel cohorts of children and adults (their parents). We examine whether hypothetically intervening to reduce childhood disadvantage could reduce adolescent obesity.</div></div><div><h3>Methods</h3><div>From a population-based cohort (N = 5107) with a mixed design (survey and direct assessment), 24–31% had genotype data: 1607 children (50% male) followed biennially from age 2–3 to 14–15; 2406 adults (36% male) followed from mean age 35–47 years. Exposures were polygenic risk score for BMI, and neighbourhood- and family-level socioeconomic disadvantage categorised as ‘most’ (top two cohort-specific quintiles), ‘average’, or ‘least’ disadvantage (bottom two quintiles). We explored trends in estimated BMI and risk of overweight/obesity by disadvantage, stratified by polygenic risk. We used generalised linear regression to estimate the reduction in overweight/obesity at 14–15 years in children living in ‘least/average disadvantage’ in early childhood relative to those in ‘most disadvantage’, adjusted for confounders. Causal effect estimates were obtained separately for children with higher and lower polygenic risk.</div></div><div><h3>Findings</h3><div>A positive trend between disadvantage and overweight/obesity was most apparent among participants with high polygenic risk. Among children with higher polygenic risk (n = 805), hypothetical target trial results imply that intervening to lessen population-wide neighbourhood disadvantage from most to least disadvantage could reduce adolescent overweight/obesity by 32% (risk ratio (RR) 0.68, 95% CI 0.50–0.92), or by 42% if intervening to lessen family disadvantage (RR 0.58, 95% CI 0.42–0.79). Positive effects were smaller when isolating the population to those with lower polygenic risk (7–17%), and for the whole population, regardless of polygenic risk (25–39%).</div></div><div><h3>Interpretation</h3><div>Children at higher polygenic risk of obesity suffer disproportionate BMI impacts of disadvantage. At the population-level, and especially for those with higher polygenic risk, tackling disadvantage could potentially reduce obesity and associated morbidity, mortality, and costs.</div></div><div><h3>Funding</h3><div><span>Australian National Health and Medical Research Council</span>. Funding information is detailed in the funding statement.</div></div>","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"53 ","pages":"Article 101231"},"PeriodicalIF":7.6,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142653198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A contemporary analysis of the Australian clinical and genetic landscape of spinal muscular atrophy: a registry based study","authors":"Lakshmi Balaji ,&nbsp;Robin Forbes ,&nbsp;Anita Cairns ,&nbsp;Hugo Sampaio ,&nbsp;Andrew J. Kornberg ,&nbsp;Lauren Sanders ,&nbsp;Phillipa Lamont ,&nbsp;Christina Liang ,&nbsp;Kristi J. Jones ,&nbsp;Kristen Nowak ,&nbsp;Cullen O'Gorman ,&nbsp;Ian Woodcock ,&nbsp;Nancy Briggs ,&nbsp;Eppie M. Yiu ,&nbsp;Michelle A. Farrar ,&nbsp;Didu Kariyawasam","doi":"10.1016/j.lanwpc.2024.101237","DOIUrl":"10.1016/j.lanwpc.2024.101237","url":null,"abstract":"<div><h3>Background</h3><div>New paradigms of diagnosis and treatment have changed the neurodegenerative trajectory for individuals with spinal muscular atrophy (SMA). Registries are a critical tool to provide real-world data on treatment patterns, their effects and health care provision within this evolving paradigm of care. This study aimed to evaluate the phenotypic and genotypic landscape, treatment patterns and health impact of SMA in Australia through the national registry.</div></div><div><h3>Methods</h3><div>This cross-sectional study investigated demographic, clinical and genetic information, sequelae of weakness, treatment patterns and patient-reported outcomes amongst individuals with SMA enrolled in the Australian Neuromuscular Disease Registry (ANMDR) from 1st January 2020 to 30th April 2023. Descriptive statistics were used for analysis and Chi-Squared or Fisher's exact tests for associations.</div></div><div><h3>Findings</h3><div>195 individuals with SMA enrolled into the ANMDR. 5/195 (2.6%) were deceased by censor date. Of (n = 190) individuals living with SMA, 104/190 (54.7%) were children. Minimum Australian prevalence was 0.73/100,000. <em>SMN2</em> copies were inversely associated with phenotype in those with homozygous <em>SMN1</em> deletions (<em>p &lt; 0.0001</em>)). Treatment was utilised in 154/190 (81%) of the population, with 65/137 (47.6%) of individuals perceiving improvements with therapeutic intervention on Patient/Parent Global Impression of Improvement scale (<em>p &lt; 0.0001</em>). Engagement with multidisciplinary care practitioners was significantly higher among children with SMA than adults (93% versus 12%, <em>p &lt; 0.0001</em>).</div></div><div><h3>Interpretation</h3><div>Despite diagnostic and therapeutic advances, mortality and the multi-systemic health impact of SMA continue to be experienced within the Australian population. Healthcare provision must align with patient-centred outcomes, adapting to meeting their changing but ongoing care requirements. The study identified the considerable unmet need for multidisciplinary care, not only for adults with SMA but also for the emerging cohort of treated children, emphasising the imperative for comprehensive healthcare provision to address their evolving needs.</div></div><div><h3>Funding</h3><div>No funding was received for this study.</div></div>","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"53 ","pages":"Article 101237"},"PeriodicalIF":7.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A complex intervention to reduce antibiotic prescribing in rural China: a cluster randomised controlled trial","authors":"Xingrong Shen ,&nbsp;Beth Stuart ,&nbsp;Enci Cui ,&nbsp;Rong Liu ,&nbsp;Tingting Zhang ,&nbsp;Jing Chai ,&nbsp;Wenjuan Cong ,&nbsp;Xiaowen Hu ,&nbsp;Isabel Oliver ,&nbsp;Guiqing Yao ,&nbsp;Paul Little ,&nbsp;Helen Lambert ,&nbsp;Lucy Yardley ,&nbsp;Christie Cabral ,&nbsp;Debin Wang","doi":"10.1016/j.lanwpc.2024.101236","DOIUrl":"10.1016/j.lanwpc.2024.101236","url":null,"abstract":"<div><h3>Background</h3><div>Excessive use of antibiotics is a widespread problem. We aim to evaluate the efficacy of a multifaceted intervention for reducing antibiotic use in patients with respiratory tract infections (RTIs).</div></div><div><h3>Methods</h3><div>In this two-arm cluster randomized controlled trial, we enrolled patients aged 18+ with symptomatic RTIs at 40 township health centers (THCs) selected from 10 counties in Anhui, China. The THCs were randomized using an online tool (‘Sealed Envelope’) to intervention or usual care (1:1 ratio), stratified by baseline antibiotic prescribing and with random block sizes (4 or 6). The intervention had five components: a half-day clinician training, a WeChat-based peer support group, a decision aid, a poster commitment letter and a patient leaflet. The primary outcome was whether antibiotics were prescribed at the index consultation. Secondary measures included defined daily dose (DDD), illness recovery rate, re-visits to other care-givers or retail pharmacies and incremental cost-effectiveness ratio (ICER). These measures were analyzed using generalized linear mixed modeling controlling for clustering. The study was registered as ISRCTN30652037.</div></div><div><h3>Findings</h3><div>Between December 2021 and September 2022, 1053 patients were recruited (intervention, 21 THCs, n = 552; control, 19 THCs, n = 501), using consecutive sampling. Antibiotic prescribing rate was 55.25% and 66.67% in the intervention and control arms (Odds ratio 0.52, 95% confidence interval [CI]: 0.27, 0.98; p = 0.044). The intervention group also had lower, significant or non-significant, differences for other markers of antibiotic use: DDD (1.57 vs 2.75); prescriptions of two or more types of antibiotics (9.78% vs 11.58%); obtaining antibiotics from retail pharmacies (3.68% vs 5.78) or from other clinics (2.70% vs 4.05%). The intervention resulted in a cost reduction of 9.265 RMB (1.471 USD) per consultation episode and an ICER of −7769.98 RMB or −1233.33 USD/QALYs. The intervention did not encounter any major adverse event.</div></div><div><h3>Interpretation</h3><div>The intervention package was effective and cost-effective in reducing antibiotics prescribing without adverse effects.</div></div><div><h3>Funding</h3><div>The trial was supported by <span>National Natural Science Foundation of China</span> (No. <span><span>81861138049</span></span>) and <span>United Kingdom Research Innovation</span> (No. <span><span>MR/S013717/1</span></span>).</div></div>","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"53 ","pages":"Article 101236"},"PeriodicalIF":7.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of time to antibiotics on clinical outcome in paediatric febrile neutropenia: a target trial emulation of 1685 episodes","authors":"Gabrielle M. Haeusler ,&nbsp;S Ghazaleh Dashti ,&nbsp;Fiona James ,&nbsp;Franz E. Babl ,&nbsp;Meredith L. Borland ,&nbsp;Julia E. Clark ,&nbsp;Bhavna Padhye ,&nbsp;Heather Tapp ,&nbsp;Frank Alvaro ,&nbsp;Trisha Soosay Raj ,&nbsp;Thomas Walwyn ,&nbsp;David S. Ziegler ,&nbsp;Leanne Super ,&nbsp;Lisa Hall ,&nbsp;Daniel K. Yeoh ,&nbsp;Coen Butters ,&nbsp;Brendan McMullan ,&nbsp;Diane M.T. Hanna ,&nbsp;Richard De Abreu Lourenco ,&nbsp;Monica A. Slavin ,&nbsp;Karin A. Thursky","doi":"10.1016/j.lanwpc.2024.101226","DOIUrl":"10.1016/j.lanwpc.2024.101226","url":null,"abstract":"<div><h3>Background</h3><div>Prompt antibiotic administration for febrile neutropenia (FN) is standard of care, and targets of time to antibiotics (TTA) &lt;60 min are common. We sought to determine the effect of TTA ≥60 versus &lt;60 min on adverse outcomes (intensive care unit (ICU) admission or death) in children with cancer and FN. Effect modification by a decision rule that predicts infection (AUS-rule) and bacteraemia were also investigated.</div></div><div><h3>Methods</h3><div>The prospective, multi-centre (n = 8), Australian PICNICC study dataset was analysed. To control for confounding, we used outcome regression adjusted for propensity score modelled as restricted cubic spline with two degrees of freedom. The propensity score was estimated from a logistic regression model for the exposure on the confounders, identified <em>a priori</em> (age, sex, severely unwell, disease, chemotherapy intensity and site). TTA was defined as time from from emergency triage to first antibiotic dose.</div></div><div><h3>Findings</h3><div>1685 FN episodes in 976 patients were included. Median TTA was 53 min (IQR 37–77 min, 1542 (92%) &lt;120 min). An adverse outcome occurred in 43 (2.6%) episodes (39 ICU; 5 deaths). The confounder-adjusted point estimate suggested a lower risk for adverse outcome associated with TTA ≥60 min (RR 0.62, 95% CI 0.32–1.21), but the wide 95% CI precluded definitive judgement about strength and direction of the effect (unadjusted RR 0.52; 95% CI 0.26, 1.05). Similarly, although the point estimates were suggestive of a null association or reduced risk for adverse outcome associated with TTA ≥60 min for all comparisons across bacteraemia or AUS-rule strata, the 95% CIs were imprecise.</div></div><div><h3>Interpretation</h3><div>For children with FN, there was no definite evidence that TTA ≥60 min from hospital triage (but within 2 h), increased risk of adverse outcome or prolonged hospital admission. This study has important implications for FN TTA mandates, suggesting a more nuanced approach is required.</div></div><div><h3>Funding</h3><div><span>National Health and Medical Research Council</span> and <span>Medical Research Future Fund</span>.</div></div>","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"53 ","pages":"Article 101226"},"PeriodicalIF":7.6,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142571438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cost-minimisation population-based analysis of telehealth-integrated antenatal care","authors":"YiJie Neo ,&nbsp;Emily Callander ,&nbsp;Ben W. Mol ,&nbsp;Ryan Hodges ,&nbsp;Kirsten R. Palmer","doi":"10.1016/j.lanwpc.2024.101239","DOIUrl":"10.1016/j.lanwpc.2024.101239","url":null,"abstract":"<div><h3>Background</h3><div>In response to the COVID-19 pandemic, Victoria’s largest maternity service provider implemented a telehealth-integrated antenatal care (ANC) schedule for high- and low-risk pregnancies. The program has been maintained since March 2020. Given ever-increasing healthcare costs, economic evaluation is crucial to ensure value and guide ongoing use.</div></div><div><h3>Methods</h3><div>The aim of the study was to perform a cost-minimisation analysis of telehealth integrated ANC compared to conventional in-person ANC, from the hospital and patient perspectives. We hypothesised that the costs associated with telehealth integrated ANC would be less than in-person ANC. We generated propensity score matched pre- and post-telehealth cohorts from women with a singleton pregnancy who received ANC and birthed at Monash Health from 1 Jan 2018–22 Mar 2020 (pre-telehealth), and 20 Apr 2020–31 Dec 2021 (post-telehealth). Data were extracted from electronic medical and finance records. We assigned costs for all Monash Health outpatient, inpatient, and emergency department episodes to calculate mean cost per birth. Patient travel costs were estimated based on distance residing from hospital.</div></div><div><h3>Findings</h3><div>Matched pre- and post-telehealth cohorts of n = 13,534 each were created. There were no significant differences in stillbirth, pre-eclampsia, severe maternal morbidity, or death. There was a AU$133 (0.98%, 95% CI [−0.17%, 2.16%]) increase in cost per birth in the post-telehealth cohort. This was driven by increased hospital costs (AU$340 or 2.64% increase, [1.44%, 3.86%]), due to a 4.78% increase in antenatal inpatient episodes and 3.51% increase in outpatient appointments post-telehealth. Increased care complexity was noted in the post-telehealth period with increased rates of gestational diabetes, caesarean birth, and specialty-led care (p-values all &lt;0.0001). In contrast, patient costs of accessing healthcare fell significantly from AU$562 pre-telehealth to AU$355 post-telehealth (difference -AU$207 (−36.81%, [−37.46%, −36.16%]).</div></div><div><h3>Interpretation</h3><div>Telehealth supported the provision of a greater volume of antenatal care to more complex pregnancies, while maintaining safety and quality of care, for only a minimal cost increase to health funders and substantial cost savings to patients. This finding provides reassurance regarding the financial viability of telehealth-integrated antenatal care.</div></div><div><h3>Funding</h3><div>None.</div></div>","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"52 ","pages":"Article 101239"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racism and health in South Korea: history, concept, and systematic review","authors":"Hayoung Lee ,&nbsp;Eun-Ji Paeng ,&nbsp;Delanjathan Devakumar ,&nbsp;Mita Huq ,&nbsp;Garin Lee ,&nbsp;Seung-Sup Kim","doi":"10.1016/j.lanwpc.2024.101228","DOIUrl":"10.1016/j.lanwpc.2024.101228","url":null,"abstract":"<div><div>To understand racism and its impact on health in South Korea, it is essential to consider the political and social context of the migrant population, including ethnic Korean migrants, marriage migrants, migrant workers, and bi-ethnic adolescents. This paper has two goals. First, we examined the increasing trends of the foreign population in South Korea, with a focus on the growth of migrant workers and marriage migrants. Following this, we reviewed the historical contexts and discussed the characteristics of racism in South Korea: ‘ethnic homogeneity’, ‘White supremacy’, and ‘ethnic discrimination against ethnic Koreans’. Second, we conducted a systematic review of 43 articles on the association between discrimination and health among racially and ethnically minoritized populations in South Korea. The review revealed statistically significant associations across various migrant groups but highlighted several limitations: all studies were cross-sectional, many used non-standardized discrimination measures, all focused on interpersonal discrimination, most examined mental health outcomes, and certain migrant groups were neglected in the research. Future research is needed to address these gaps.</div></div><div><h3>Funding</h3><div>This work was supported by the <span>New Faculty Startup</span> Fund from Seoul <span>National University</span>.</div></div>","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"52 ","pages":"Article 101228"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why I decide to leave South Korea healthcare system","authors":"Jounggi Moon ,&nbsp;Joo-Young Lee","doi":"10.1016/j.lanwpc.2024.101232","DOIUrl":"10.1016/j.lanwpc.2024.101232","url":null,"abstract":"","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"52 ","pages":"Article 101232"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142554270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progress and challenges of confirmatory trials for cancer drugs granted conditional approval in China","authors":"Xingxian Luo ,&nbsp;Yang Xu ,&nbsp;Xin Du ,&nbsp;Xufeng Lv ,&nbsp;Si Chen ,&nbsp;Yue Yang ,&nbsp;Lin Huang ,&nbsp;Xiaohong Zhang","doi":"10.1016/j.lanwpc.2024.101238","DOIUrl":"10.1016/j.lanwpc.2024.101238","url":null,"abstract":"","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"52 ","pages":"Article 101238"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards an agenda of action and research for making health systems responsive to the needs of people with disabilities","authors":"Thi Vinh Nguyen,&nbsp;Sumit Kane","doi":"10.1016/j.lanwpc.2024.101225","DOIUrl":"10.1016/j.lanwpc.2024.101225","url":null,"abstract":"<div><div>Ensuring health systems responsiveness is crucial for health equity and outcomes of all individuals, particularly disadvantaged groups such as people with disabilities. However, attention to and discussions on health system responsiveness for people with disabilities remains lacking. This viewpoint highlights the pervasive issues within health systems rooted in ableism and proposes an agenda to tackle ableism, aiming to make health systems responsive to the needs of people with disabilities. Their needs are complex and diverse, varying with the disability, its severity, progression, and intersection with other factors. Ableism creates significant obstacles to identifying and addressing their needs and expectations, damages provider–patient interactions, poses multiple challenges in healthcare, and impacts the overall responsiveness of the health system to the populations it is meant to serve. The proposed agenda outlines areas for action and research across six building blocks of health systems as a way forward to enhance the health system's responsiveness to the needs of people with disabilities.</div></div>","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"52 ","pages":"Article 101225"},"PeriodicalIF":7.6,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human carcinogen, leisure food, or local specialty: navigating areca nut regulation in China","authors":"Jiayi Jiang,&nbsp;Zexing Zheng","doi":"10.1016/j.lanwpc.2024.101230","DOIUrl":"10.1016/j.lanwpc.2024.101230","url":null,"abstract":"","PeriodicalId":22792,"journal":{"name":"The Lancet Regional Health: Western Pacific","volume":"52 ","pages":"Article 101230"},"PeriodicalIF":7.6,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}