{"title":"Evidence for a reduction in number of cycles of immune checkpoint inhibitors","authors":"Abdul-Hamid Bazarbachi, Nicola Magrini, Zeba Aziz, Tito Fojo","doi":"10.1016/s1470-2045(24)00594-1","DOIUrl":"https://doi.org/10.1016/s1470-2045(24)00594-1","url":null,"abstract":"No Abstract","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1016/s1470-2045(24)00395-4
Hedvig Hricak, Marius E Mayerhoefer, Ken Herrmann, Jason S Lewis, Martin G Pomper, Christopher P Hess, Katrine Riklund, Andrew M Scott, Ralph Weissleder
Technological innovations in genomics and related fields have facilitated large sequencing efforts, supported new biological discoveries in cancer, and spawned an era of liquid biopsy biomarkers. Despite these advances, precision oncology has practical constraints, partly related to cancer's biological diversity and spatial and temporal complexity. Advanced imaging technologies are being developed to address some of the current limitations in early detection, treatment selection and planning, drug delivery, and therapeutic response, as well as difficulties posed by drug resistance, drug toxicity, disease monitoring, and metastatic evolution. We discuss key areas of advanced imaging for improving cancer outcomes and survival. Finally, we discuss practical challenges to the broader adoption of precision imaging in the clinic and the need for a robust translational infrastructure.
{"title":"Advances and challenges in precision imaging","authors":"Hedvig Hricak, Marius E Mayerhoefer, Ken Herrmann, Jason S Lewis, Martin G Pomper, Christopher P Hess, Katrine Riklund, Andrew M Scott, Ralph Weissleder","doi":"10.1016/s1470-2045(24)00395-4","DOIUrl":"https://doi.org/10.1016/s1470-2045(24)00395-4","url":null,"abstract":"Technological innovations in genomics and related fields have facilitated large sequencing efforts, supported new biological discoveries in cancer, and spawned an era of liquid biopsy biomarkers. Despite these advances, precision oncology has practical constraints, partly related to cancer's biological diversity and spatial and temporal complexity. Advanced imaging technologies are being developed to address some of the current limitations in early detection, treatment selection and planning, drug delivery, and therapeutic response, as well as difficulties posed by drug resistance, drug toxicity, disease monitoring, and metastatic evolution. We discuss key areas of advanced imaging for improving cancer outcomes and survival. Finally, we discuss practical challenges to the broader adoption of precision imaging in the clinic and the need for a robust translational infrastructure.","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1016/s1470-2045(24)00658-2
S Michael Crawford
No Abstract
没有抽象的
{"title":"Risk-prediction models and clinical challenges in the ROCketS study","authors":"S Michael Crawford","doi":"10.1016/s1470-2045(24)00658-2","DOIUrl":"https://doi.org/10.1016/s1470-2045(24)00658-2","url":null,"abstract":"No Abstract","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1016/s1470-2045(24)00680-6
Cécile Le Pechoux, Angela Botticella, Antonin Levy
No Abstract
没有抽象的
{"title":"Full-dose SBRT for the primary tumour in stage III NSCLC: a promising and safe way to selective dose escalation?","authors":"Cécile Le Pechoux, Angela Botticella, Antonin Levy","doi":"10.1016/s1470-2045(24)00680-6","DOIUrl":"https://doi.org/10.1016/s1470-2045(24)00680-6","url":null,"abstract":"No Abstract","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1016/s1470-2045(24)00713-7
Vora S, Pafundi D, Voss M, et al. Short-course hypofractionated proton beam therapy, incorporating 18F-DOPA PET and contrast-enhanced MRI targeting, for patients aged 65 years and older with newly diagnosed glioblastoma: a single-arm phase 2 trial. Lancet Oncol 2024; 25: 1625–34—In this Article, the spelling of author Bernard R Bendok's name was incorrect. This correction has been made to the online version as of Jan 2, 2025.
{"title":"Correction to Lancet Oncol 2024; 25: 1625–34","authors":"","doi":"10.1016/s1470-2045(24)00713-7","DOIUrl":"https://doi.org/10.1016/s1470-2045(24)00713-7","url":null,"abstract":"<em>Vora S, Pafundi D, Voss M, et al. Short-course hypofractionated proton beam therapy, incorporating <sup>18</sup>F-DOPA PET and contrast-enhanced MRI targeting, for patients aged 65 years and older with newly diagnosed glioblastoma: a single-arm phase 2 trial.</em> Lancet Oncol <em>2024; <strong>25</strong>: <em>1625–34</em>—In this Article, the spelling of author Bernard R Bendok's name was incorrect. This correction has been made to the online version as of Jan 2, 2025.</em>","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1016/s1470-2045(24)00724-1
No Abstract
没有抽象的
{"title":"Prioritising oral health in cancer care","authors":"","doi":"10.1016/s1470-2045(24)00724-1","DOIUrl":"https://doi.org/10.1016/s1470-2045(24)00724-1","url":null,"abstract":"No Abstract","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"371 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1016/s1470-2045(24)00641-7
Cheryl Reeves, Smriti Patodia, David Collingridge
No Abstract
没有抽象的
{"title":"Carolyn Taylor and Global Focus on Cancer","authors":"Cheryl Reeves, Smriti Patodia, David Collingridge","doi":"10.1016/s1470-2045(24)00641-7","DOIUrl":"https://doi.org/10.1016/s1470-2045(24)00641-7","url":null,"abstract":"No Abstract","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1016/s1470-2045(24)00639-9
Liqi Li
No Abstract
没有抽象的
{"title":"FNAB samples with the STRAT4 assay for breast cancer diagnosis","authors":"Liqi Li","doi":"10.1016/s1470-2045(24)00639-9","DOIUrl":"https://doi.org/10.1016/s1470-2045(24)00639-9","url":null,"abstract":"No Abstract","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"30 20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1016/s1470-2045(24)00625-9
Bei Feng, Yan Feng, Juanjuan Huang, Tao Liu, Jie Qin
No Abstract
没有抽象的
{"title":"Risk-prediction models and clinical challenges in the ROCkeTS study","authors":"Bei Feng, Yan Feng, Juanjuan Huang, Tao Liu, Jie Qin","doi":"10.1016/s1470-2045(24)00625-9","DOIUrl":"https://doi.org/10.1016/s1470-2045(24)00625-9","url":null,"abstract":"No Abstract","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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