Pub Date : 2025-12-01DOI: 10.1016/s1470-2045(25)00526-1
Andrea L Cheville, Jeph Herrin, Deirdre R Pachman, Veronica Grzegorczyk, Kurt Kroenke, Jennifer L Ridgeway, Sarah A Minteer, Jessica D Austin, Joan M Griffin, Linda Chlan, Cindy Tofthagen, Sandra A Mitchell, Ashley Smith, Kathryn J Ruddy
<h3>Background</h3>Patient-reported outcome measure (PROM) surveillance and collaborative care improve cancer symptom control. However, human resource requirements constrain their implementation and reach. Electronic health record (EHR) facilitation reduces resource needs and might allow population-level scaling. We aimed to assess the effect of EHR facilitation of PROM-directed collaborative care on clinical and health services outcomes.<h3>Methods</h3>E2C2 was a cohort cluster-randomised, unblinded, stepped-wedge, pragmatic trial, in which we randomly assigned 15 clusters of medical oncology and haematology clinics in the USA sharing a common EHR, Epic, to five sequences to compare an intervention of remotely delivered electronic PROM (ePROM) symptom surveillance and EHR-facilitated collaborative care (ECC) management with a usual care (UC) control of ePROM surveillance alone. Sequences transitioned from the UC control to the ECC intervention state at 8-month intervals. All adult (aged ≥18 years) patients who received medical oncology or haematology care in a US multi-state health system were enrolled. All cancer stages, cancer types, and treatment phases were included, except for patients enrolled in hospice or with acute leukaemia. SPPADE symptoms (sleep interference, pain, impaired physical function, anxiety, depression, and energy deficit or fatigue) were assessed with 0–10-point numerical rating scales linked to clinical encounters. The prespecified co-primary outcomes were all post-baseline SPPADE scores, and clinically actionable scores (≥4/10), among participants who completed at least two ePROMs. The outcomes were assessed using multivariate regression of cluster-period mean SPPADE symptom scores against intervention exposure, baseline SPPADE scores, fixed-cluster, and secular time effects. The trial is registered at <span><span>ClinicalTrials.gov</span><svg aria-label="Opens in new window" focusable="false" height="20" viewbox="0 0 8 8"><path d="M1.12949 2.1072V1H7V6.85795H5.89111V2.90281L0.784057 8L0 7.21635L5.11902 2.1072H1.12949Z"></path></svg></span> (<span><span>NCT03892967</span><svg aria-label="Opens in new window" focusable="false" height="20" viewbox="0 0 8 8"><path d="M1.12949 2.1072V1H7V6.85795H5.89111V2.90281L0.784057 8L0 7.21635L5.11902 2.1072H1.12949Z"></path></svg></span>) and is now closed to recruitment.<h3>Findings</h3>From March 28, 2019, to Jan 31, 2023, 50 207 patients were enrolled and administered ePROMs in association with oncology or haematology visits. In the analytical cohort of 24 874 participants, 10 390 (42%) were assigned ePROMS in both the ECC and UC periods. Of the 19 084 [77%] in the ECC group, 11 138 (58%) were female, 7946 (42%) were male, and 18189 (95%) were White; and of the 16 180 (65%) in the UC group, 9621 (60%) were female, 6559 (40%) were male, and 15468 (96%) were White. 21 153 (85%) participants reported one or more clinically actionable symptoms (defined as SPPADE score ≥4/10). In multiva
{"title":"Electronic health record-facilitated symptom surveillance and collaborative care intervention in oncology (E2C2): a cluster-randomised, population-level, stepped-wedge, pragmatic trial","authors":"Andrea L Cheville, Jeph Herrin, Deirdre R Pachman, Veronica Grzegorczyk, Kurt Kroenke, Jennifer L Ridgeway, Sarah A Minteer, Jessica D Austin, Joan M Griffin, Linda Chlan, Cindy Tofthagen, Sandra A Mitchell, Ashley Smith, Kathryn J Ruddy","doi":"10.1016/s1470-2045(25)00526-1","DOIUrl":"https://doi.org/10.1016/s1470-2045(25)00526-1","url":null,"abstract":"<h3>Background</h3>Patient-reported outcome measure (PROM) surveillance and collaborative care improve cancer symptom control. However, human resource requirements constrain their implementation and reach. Electronic health record (EHR) facilitation reduces resource needs and might allow population-level scaling. We aimed to assess the effect of EHR facilitation of PROM-directed collaborative care on clinical and health services outcomes.<h3>Methods</h3>E2C2 was a cohort cluster-randomised, unblinded, stepped-wedge, pragmatic trial, in which we randomly assigned 15 clusters of medical oncology and haematology clinics in the USA sharing a common EHR, Epic, to five sequences to compare an intervention of remotely delivered electronic PROM (ePROM) symptom surveillance and EHR-facilitated collaborative care (ECC) management with a usual care (UC) control of ePROM surveillance alone. Sequences transitioned from the UC control to the ECC intervention state at 8-month intervals. All adult (aged ≥18 years) patients who received medical oncology or haematology care in a US multi-state health system were enrolled. All cancer stages, cancer types, and treatment phases were included, except for patients enrolled in hospice or with acute leukaemia. SPPADE symptoms (sleep interference, pain, impaired physical function, anxiety, depression, and energy deficit or fatigue) were assessed with 0–10-point numerical rating scales linked to clinical encounters. The prespecified co-primary outcomes were all post-baseline SPPADE scores, and clinically actionable scores (≥4/10), among participants who completed at least two ePROMs. The outcomes were assessed using multivariate regression of cluster-period mean SPPADE symptom scores against intervention exposure, baseline SPPADE scores, fixed-cluster, and secular time effects. The trial is registered at <span><span>ClinicalTrials.gov</span><svg aria-label=\"Opens in new window\" focusable=\"false\" height=\"20\" viewbox=\"0 0 8 8\"><path d=\"M1.12949 2.1072V1H7V6.85795H5.89111V2.90281L0.784057 8L0 7.21635L5.11902 2.1072H1.12949Z\"></path></svg></span> (<span><span>NCT03892967</span><svg aria-label=\"Opens in new window\" focusable=\"false\" height=\"20\" viewbox=\"0 0 8 8\"><path d=\"M1.12949 2.1072V1H7V6.85795H5.89111V2.90281L0.784057 8L0 7.21635L5.11902 2.1072H1.12949Z\"></path></svg></span>) and is now closed to recruitment.<h3>Findings</h3>From March 28, 2019, to Jan 31, 2023, 50 207 patients were enrolled and administered ePROMs in association with oncology or haematology visits. In the analytical cohort of 24 874 participants, 10 390 (42%) were assigned ePROMS in both the ECC and UC periods. Of the 19 084 [77%] in the ECC group, 11 138 (58%) were female, 7946 (42%) were male, and 18189 (95%) were White; and of the 16 180 (65%) in the UC group, 9621 (60%) were female, 6559 (40%) were male, and 15468 (96%) were White. 21 153 (85%) participants reported one or more clinically actionable symptoms (defined as SPPADE score ≥4/10). In multiva","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145651224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/s1470-2045(25)00564-9
Kelly M Shaffer, Roger Anderson
No Abstract
没有抽象的
{"title":"The promise of scalable symptom surveillance with stepped collaborative care in oncology","authors":"Kelly M Shaffer, Roger Anderson","doi":"10.1016/s1470-2045(25)00564-9","DOIUrl":"https://doi.org/10.1016/s1470-2045(25)00564-9","url":null,"abstract":"No Abstract","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145657254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-27DOI: 10.1016/s1470-2045(25)00713-2
Kark Gruber
{"title":"New South Wales expands cancer coverage for firefighters","authors":"Kark Gruber","doi":"10.1016/s1470-2045(25)00713-2","DOIUrl":"https://doi.org/10.1016/s1470-2045(25)00713-2","url":null,"abstract":"","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145611836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-27DOI: 10.1016/s1470-2045(25)00711-9
Sharmila Devi
{"title":"Europe is falling behind on targets to address AMR","authors":"Sharmila Devi","doi":"10.1016/s1470-2045(25)00711-9","DOIUrl":"https://doi.org/10.1016/s1470-2045(25)00711-9","url":null,"abstract":"","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145611837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-25DOI: 10.1016/s1470-2045(25)00463-2
André Pfob, Katja Pinker, Ines Vaz-Luis, Antonio Di Meglio, Maria João Cardoso, Giuseppe Curigliano, Oreste Davide Gentilini, Günther Gruber, Nik Hauser, Jörg Heil, Orit Kaidar-Person, Michael Knauer, Han-Byoel Lee, Sae Byul Lee, Sherene Loi, Meinrad Mannhart, Stella Mastora, Icro Meattini, Rosa Di Micco, Aurelia Noske, Fedro Alessandro Peccatori, Fiorita Poulakaki, Mattea Reinisch, Isabel T Rubio, Charlie Swanton, Christoph Tausch, Marie-Jeanne Vrancken Peeters, Jong Han Yu, Walter Paul Weber, Norman Zerbe, Philip Poortmans, Carsten Denkert, Ritse Mann, Suzette Delaloge, Peter Dubsky, Alexandra Athanasiou, Marianne Aznar, Thomas Bachelot, Zsuzsanna Bago-Horvath, Maggie Banys-Paluchowski, Sophia Belouka, Almir Bitencourt, Liesbeth Boersma, Kimberly Bowles, Roswitha Britz, Samantha Brunsden, Carmela Caballero, Julia Camps-Herrero, Giuseppe F Catanuto, Effimia Chatzinikolaou, Charlotte Coles, Stefanie Corradini, Terri Coutee, Jana de Boniface, Antonio Di Meglio, Joachim Diebold, Susanne Dieroff Hay, Nina Ditsch, David Dodwell, Ian Ellis, Sarah Eskreis-Winkler, Pierfrancesco Franco, Maria Alice Franzoi, Helen Frazer, Thomas frederic-moreau, Michael Fuchsjäger, Dorota Gabryś, Ursula Ganz-Blättler, Maria Luisa Gasparri, Mami Iima, Eva Karamitopoulou, Maria Katapodi, Marietta Kirchner, Antigoni Kretsi, Randi Krogsgaard, David Krug, Thorsten Kuehn, Christiane Kuhl, Kristina Lång, Kyung-Hun Lee, Sae Byul Lee, Hee Jin Lee, Vincenzo L'Imperio, Mairead MacKenzie, Maja Vestmø Maraldo, Stuart A McIntosh, Ingvil Mjaaland, Angel Montero, Linda Moy, Rosine Mucklow, Sudeshen Naidoo, Anu Niemi, Federica Pediconi, Frederique Penault-Llorca, Marlen Pfeiffer, André Pfob, Katja Pinker, Niklas Prenissl, Nina Radosevic-Robin, Duvern Ramiah, Ivica Ratosa, Tilman Rau, Evangelia Razis, Peter Regitnig, Nicola Rocco, Patrizia Sager, Pedro F Saint-Maurice, Anja Sander, Francesco Sardanelli, Elisabet Schesny, Simone Schiaffino, Alexander Schipf, Maximilian Schuessler, Jane Shaw, Davide Soldato, Stamatis Stamatelopoulos, Petra Steyerova, Philipp Ströbel, Laura Testa, Thiemo J A van Nijnatten, Ines Vaz, Ines Vaz Luis, Sara E Vazquez-Manjarrez, Maria Vidal, Jose Volders, Markus Wallwiener, Lynda Wyld, Nicholas Zdenkowski
{"title":"The Lucerne Toolbox 3: digital health and artificial intelligence to optimise the patient journey in early breast cancer—a multidisciplinary consensus","authors":"André Pfob, Katja Pinker, Ines Vaz-Luis, Antonio Di Meglio, Maria João Cardoso, Giuseppe Curigliano, Oreste Davide Gentilini, Günther Gruber, Nik Hauser, Jörg Heil, Orit Kaidar-Person, Michael Knauer, Han-Byoel Lee, Sae Byul Lee, Sherene Loi, Meinrad Mannhart, Stella Mastora, Icro Meattini, Rosa Di Micco, Aurelia Noske, Fedro Alessandro Peccatori, Fiorita Poulakaki, Mattea Reinisch, Isabel T Rubio, Charlie Swanton, Christoph Tausch, Marie-Jeanne Vrancken Peeters, Jong Han Yu, Walter Paul Weber, Norman Zerbe, Philip Poortmans, Carsten Denkert, Ritse Mann, Suzette Delaloge, Peter Dubsky, Alexandra Athanasiou, Marianne Aznar, Thomas Bachelot, Zsuzsanna Bago-Horvath, Maggie Banys-Paluchowski, Sophia Belouka, Almir Bitencourt, Liesbeth Boersma, Kimberly Bowles, Roswitha Britz, Samantha Brunsden, Carmela Caballero, Julia Camps-Herrero, Giuseppe F Catanuto, Effimia Chatzinikolaou, Charlotte Coles, Stefanie Corradini, Terri Coutee, Jana de Boniface, Antonio Di Meglio, Joachim Diebold, Susanne Dieroff Hay, Nina Ditsch, David Dodwell, Ian Ellis, Sarah Eskreis-Winkler, Pierfrancesco Franco, Maria Alice Franzoi, Helen Frazer, Thomas frederic-moreau, Michael Fuchsjäger, Dorota Gabryś, Ursula Ganz-Blättler, Maria Luisa Gasparri, Mami Iima, Eva Karamitopoulou, Maria Katapodi, Marietta Kirchner, Antigoni Kretsi, Randi Krogsgaard, David Krug, Thorsten Kuehn, Christiane Kuhl, Kristina Lång, Kyung-Hun Lee, Sae Byul Lee, Hee Jin Lee, Vincenzo L'Imperio, Mairead MacKenzie, Maja Vestmø Maraldo, Stuart A McIntosh, Ingvil Mjaaland, Angel Montero, Linda Moy, Rosine Mucklow, Sudeshen Naidoo, Anu Niemi, Federica Pediconi, Frederique Penault-Llorca, Marlen Pfeiffer, André Pfob, Katja Pinker, Niklas Prenissl, Nina Radosevic-Robin, Duvern Ramiah, Ivica Ratosa, Tilman Rau, Evangelia Razis, Peter Regitnig, Nicola Rocco, Patrizia Sager, Pedro F Saint-Maurice, Anja Sander, Francesco Sardanelli, Elisabet Schesny, Simone Schiaffino, Alexander Schipf, Maximilian Schuessler, Jane Shaw, Davide Soldato, Stamatis Stamatelopoulos, Petra Steyerova, Philipp Ströbel, Laura Testa, Thiemo J A van Nijnatten, Ines Vaz, Ines Vaz Luis, Sara E Vazquez-Manjarrez, Maria Vidal, Jose Volders, Markus Wallwiener, Lynda Wyld, Nicholas Zdenkowski","doi":"10.1016/s1470-2045(25)00463-2","DOIUrl":"https://doi.org/10.1016/s1470-2045(25)00463-2","url":null,"abstract":"","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"229 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145592808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-25DOI: 10.1016/s1470-2045(25)00525-x
Tarek Bou Dargham, Sebastian F Winter, Kristen Batich, Karin Gehring, Michael W Parsons, Jorg Dietrich, Trey Mullikin, Zachary J Reitman, Scott R Floyd, John P Kirkpatrick, Paul W Sperduto, Jona Hattangadi-Gluth, Helen A Shih, Paul D Brown, Minesh Mehta, Erik P Sulman, Katherine B Peters, Eugene J Vaios
{"title":"Neurocognitive outcomes in patients with brain metastases: a systematic review","authors":"Tarek Bou Dargham, Sebastian F Winter, Kristen Batich, Karin Gehring, Michael W Parsons, Jorg Dietrich, Trey Mullikin, Zachary J Reitman, Scott R Floyd, John P Kirkpatrick, Paul W Sperduto, Jona Hattangadi-Gluth, Helen A Shih, Paul D Brown, Minesh Mehta, Erik P Sulman, Katherine B Peters, Eugene J Vaios","doi":"10.1016/s1470-2045(25)00525-x","DOIUrl":"https://doi.org/10.1016/s1470-2045(25)00525-x","url":null,"abstract":"","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145592815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-25DOI: 10.1016/s1470-2045(25)00542-x
Alessio Amatu, Giorgio Patelli, Maria Giulia Zampino, Francesca Bergamo, Stefania Mosconi, Federica Tosi, Davide Ciardiello, Sara Lonardi, Giorgia Negrini, Daniela Sibio, Marianna Alessandra Gerardi, Sara Galuppo, Francesco Romeo Filippone, Pietro Carnevali, Simona Borin, Pierluigi Pilati, Elia Poiasina, Erica Bonazzina, Lorenzo Gervaso, Enzo Mammano, Francesco Bracco, Luca Bergamaschi, Gaya Spolverato, Matteo Origi, Uberto Fumagalli Romario, Gianluca Mauri, Nicola Fazio, Edoardo Forti, Giuseppe De Roberto, Chiara Cristofori, Cesare Burti, Luigi Asmundo, Luigi Funicelli, Gaetano Ramondo, Pietro Andrea Bonaffini, Sara Mariano, Luca Lazzari, Silvia Ghezzi, Claudio Isella, Daniela Cantarella, Maria Costanza Aquilano, Luca Bottiglieri, Emanuela Bonoldi, Massimiliano Mutignani, Valter Torri, Enzo Medico, Alberto Bardelli, Silvia Marsoni, Angelo Vanzulli, Mauro Filippo Palazzi, Giovanni Carlo Ferrari, Katia Bencardino, Andrea Sartore-Bianchi, Salvatore Siena
{"title":"Total neoadjuvant therapy followed by non-operative management or surgery in stage II–III rectal cancer (NO-CUT): a multicentre, single-arm, phase 2 trial","authors":"Alessio Amatu, Giorgio Patelli, Maria Giulia Zampino, Francesca Bergamo, Stefania Mosconi, Federica Tosi, Davide Ciardiello, Sara Lonardi, Giorgia Negrini, Daniela Sibio, Marianna Alessandra Gerardi, Sara Galuppo, Francesco Romeo Filippone, Pietro Carnevali, Simona Borin, Pierluigi Pilati, Elia Poiasina, Erica Bonazzina, Lorenzo Gervaso, Enzo Mammano, Francesco Bracco, Luca Bergamaschi, Gaya Spolverato, Matteo Origi, Uberto Fumagalli Romario, Gianluca Mauri, Nicola Fazio, Edoardo Forti, Giuseppe De Roberto, Chiara Cristofori, Cesare Burti, Luigi Asmundo, Luigi Funicelli, Gaetano Ramondo, Pietro Andrea Bonaffini, Sara Mariano, Luca Lazzari, Silvia Ghezzi, Claudio Isella, Daniela Cantarella, Maria Costanza Aquilano, Luca Bottiglieri, Emanuela Bonoldi, Massimiliano Mutignani, Valter Torri, Enzo Medico, Alberto Bardelli, Silvia Marsoni, Angelo Vanzulli, Mauro Filippo Palazzi, Giovanni Carlo Ferrari, Katia Bencardino, Andrea Sartore-Bianchi, Salvatore Siena","doi":"10.1016/s1470-2045(25)00542-x","DOIUrl":"https://doi.org/10.1016/s1470-2045(25)00542-x","url":null,"abstract":"","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145593402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-25DOI: 10.1016/s1470-2045(25)00663-1
Clifford A Hudis, Elizabeth Garrett-Mayer
{"title":"Of surrogate endpoints, shortcuts, and safety","authors":"Clifford A Hudis, Elizabeth Garrett-Mayer","doi":"10.1016/s1470-2045(25)00663-1","DOIUrl":"https://doi.org/10.1016/s1470-2045(25)00663-1","url":null,"abstract":"","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145592802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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