Certain HIV drugs in the nucleoside reverse transcriptase inhibitor (NRTI) class sometimes have negative side effects [2] that may lead to liver and other problems. One such side effect is damage to the mitochondria inside your cells, or mitochondrial toxicity. When mitochondria are damaged, lactic acid production is increased. This can cause levels of lactic acid in your blood to rise. If the levels of lactic acid become too high, a rare, but serious condition called lactic acidosis can occur.
{"title":"Lactic acidosis.","authors":"R. Park","doi":"10.32388/b6vu52","DOIUrl":"https://doi.org/10.32388/b6vu52","url":null,"abstract":"Certain HIV drugs in the nucleoside reverse transcriptase inhibitor (NRTI) class sometimes have negative side effects [2] that may lead to liver and other problems. One such side effect is damage to the mitochondria inside your cells, or mitochondrial toxicity. When mitochondria are damaged, lactic acid production is increased. This can cause levels of lactic acid in your blood to rise. If the levels of lactic acid become too high, a rare, but serious condition called lactic acidosis can occur.","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"21 1","pages":"418-24"},"PeriodicalIF":0.0,"publicationDate":"2020-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75951126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-07DOI: 10.1007/978-1-4020-6754-9_10098
Steven, J. Koga, M. Hodges, C. Markin, Paul Gorman
{"title":"MELAS syndrome.","authors":"Steven, J. Koga, M. Hodges, C. Markin, Paul Gorman","doi":"10.1007/978-1-4020-6754-9_10098","DOIUrl":"https://doi.org/10.1007/978-1-4020-6754-9_10098","url":null,"abstract":"","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"1 1","pages":"379-81"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88259959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A myelodysplastic syndrome characterized mainly by dysplasia of the erythroid series. Refractory anemia is uncommon. It is primarily a disease of older adults. The median survival exceeds 5 years.
{"title":"Refractory anemia.","authors":"G. Cartwright","doi":"10.32388/j73ty7","DOIUrl":"https://doi.org/10.32388/j73ty7","url":null,"abstract":"A myelodysplastic syndrome characterized mainly by dysplasia of the erythroid series. Refractory anemia is uncommon. It is primarily a disease of older adults. The median survival exceeds 5 years.","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"33 1","pages":"137"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76932301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Limb.","authors":"J. Marshall","doi":"10.32388/6hflb4","DOIUrl":"https://doi.org/10.32388/6hflb4","url":null,"abstract":"","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"46 1","pages":"697"},"PeriodicalIF":0.0,"publicationDate":"2020-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73339483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-24DOI: 10.21037/ales.2019.09.03
M. Stamos, H. Vargas
Minimally invasive approaches to general surgical procedures became popularized over the decade following its introduction by Erich Muhe in 1982. It is now universally accepted that laparoscopy is associated with decreased post-operative pain and length of stay.
{"title":"Laparoscopic colon surgery.","authors":"M. Stamos, H. Vargas","doi":"10.21037/ales.2019.09.03","DOIUrl":"https://doi.org/10.21037/ales.2019.09.03","url":null,"abstract":"Minimally invasive approaches to general surgical procedures became popularized over the decade following its introduction by Erich Muhe in 1982. It is now universally accepted that laparoscopy is associated with decreased post-operative pain and length of stay.","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"8 1","pages":"41-2"},"PeriodicalIF":0.0,"publicationDate":"2019-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79118918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-15DOI: 10.7591/9781501735486-008
M. Carroll
When, in the interest of wellness, it becomes necessary for healers from multiple traditions to renounce the narcissism eroding their collective health care, and to re-assume, in the midst of growing interpersonal greed, the selfless and service-oriented station to which nature and its Creator call them, a deep empathy for sick people compels them to declare their shared vision of healing. We hold these truths to be self-evident, that all people are born to an interdependent whole; that illness embodies isolation from the whole; that ill people are entitled to kindness, compassion, and blameless charity in their pursuit to re-experience the whole. That to help ill people return to the whole, hospitals and health care systems are instituted among communities, deriving their sacred authority from the confidence of the sick; that whenever any hospital or health care system recklessly segregates the sick, it is the obligation of healers to change or abandon it, and to organize new centers and systems of healing that remain faithful to the basic precepts of compassionate caring and interdependence. Convention and financial comfort, no doubt, will prevent the radical revision of ailing medical systems without just cause. Nonetheless, when a record of spiritless policies clearly evidences apathy instead of empathy in the health care system, it is healers' moral duty to disavow such callous indifference, and refocus professional attention on the heart and soul of caring. Such has been the sad witness of contemporary physicians and healers from many traditions; and such are now the circumstances that press them to reassert the primary place of charity and kindness in the healing professions. The recent history of the current health care system is one of repeated assaults against the commitment to compassion. To demonstrate this, let harsh realities be reviewed by a disillusioned world: The health care system places money before people. Witness the emphasis on consumerism rather than caring, the refusal of some facilities to treat the indigent and the uninsured, the motivation of corporations to profit from illness and despair. The health care system studies instead of believes. Notice how physicians invoke science to prove the worthiness of compassion, how researchers search for statistics that social support improves outcomes, how concerns over resource allocation have silenced the spirit of charity in contemporary healing. The health care system seeks control over diverse traditions, not integration with them. Acknowledge that much interest to integrate “alternative” healing practices followed surveys showing widespread use of such practices, that some new clinics juxtapose healing traditions without considering whether different traditions should be integrated, that academicians subject alternative traditions to standard statistical analysis when assessing outcomes and efficacy. The health care system embraces an ethic of se
{"title":"A declaration of interdependence.","authors":"M. Carroll","doi":"10.7591/9781501735486-008","DOIUrl":"https://doi.org/10.7591/9781501735486-008","url":null,"abstract":"When, in the interest of wellness, it becomes necessary for healers from multiple traditions to renounce the narcissism eroding their collective health care, and to re-assume, in the midst of growing interpersonal greed, the selfless and service-oriented station to which nature and its Creator call them, a deep empathy for sick people compels them to declare their shared vision of healing. \u0000 \u0000We hold these truths to be self-evident, that all people are born to an interdependent whole; that illness embodies isolation from the whole; that ill people are entitled to kindness, compassion, and blameless charity in their pursuit to re-experience the whole. That to help ill people return to the whole, hospitals and health care systems are instituted among communities, deriving their sacred authority from the confidence of the sick; that whenever any hospital or health care system recklessly segregates the sick, it is the obligation of healers to change or abandon it, and to organize new centers and systems of healing that remain faithful to the basic precepts of compassionate caring and interdependence. Convention and financial comfort, no doubt, will prevent the radical revision of ailing medical systems without just cause. Nonetheless, when a record of spiritless policies clearly evidences apathy instead of empathy in the health care system, it is healers' moral duty to disavow such callous indifference, and refocus professional attention on the heart and soul of caring. Such has been the sad witness of contemporary physicians and healers from many traditions; and such are now the circumstances that press them to reassert the primary place of charity and kindness in the healing professions. \u0000 \u0000The recent history of the current health care system is one of repeated assaults against the commitment to compassion. To demonstrate this, let harsh realities be reviewed by a disillusioned world: \u0000 \u0000 \u0000 \u0000The health care system places money before people. Witness the emphasis on consumerism rather than caring, the refusal of some facilities to treat the indigent and the uninsured, the motivation of corporations to profit from illness and despair. \u0000 \u0000 \u0000The health care system studies instead of believes. Notice how physicians invoke science to prove the worthiness of compassion, how researchers search for statistics that social support improves outcomes, how concerns over resource allocation have silenced the spirit of charity in contemporary healing. \u0000 \u0000 \u0000The health care system seeks control over diverse traditions, not integration with them. Acknowledge that much interest to integrate “alternative” healing practices followed surveys showing widespread use of such practices, that some new clinics juxtapose healing traditions without considering whether different traditions should be integrated, that academicians subject alternative traditions to standard statistical analysis when assessing outcomes and efficacy. \u0000 \u0000 \u0000The health care system embraces an ethic of se","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"51 1","pages":"66"},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78995558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.4135/9781483380810.n621
G. M. Hunt, D. I. Peterson
,
{"title":"Tardive dyskinesia.","authors":"G. M. Hunt, D. I. Peterson","doi":"10.4135/9781483380810.n621","DOIUrl":"https://doi.org/10.4135/9781483380810.n621","url":null,"abstract":",","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"206 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86951487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-31DOI: 10.1515/9781400888962-003
F. Sterle
{"title":"Chronic condition.","authors":"F. Sterle","doi":"10.1515/9781400888962-003","DOIUrl":"https://doi.org/10.1515/9781400888962-003","url":null,"abstract":"","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"36 1","pages":"44"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87035428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Too many lawyers?","authors":"Msmw","doi":"10.4324/9781315449807","DOIUrl":"https://doi.org/10.4324/9781315449807","url":null,"abstract":"","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"2014 1","pages":"88"},"PeriodicalIF":0.0,"publicationDate":"2018-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89516523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Violence in America.","authors":"D. Stolinsky","doi":"10.4324/9781315315560","DOIUrl":"https://doi.org/10.4324/9781315315560","url":null,"abstract":"","PeriodicalId":22925,"journal":{"name":"The Western journal of medicine","volume":"11 1","pages":"397-8"},"PeriodicalIF":0.0,"publicationDate":"2018-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84811534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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