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Relationship between sarcopenia and diabetic nephropathy 肌肉减少症与糖尿病肾病的关系
Pub Date : 2022-01-01 DOI: 10.4103/sjamf.sjamf_243_21
S. Mohamed, Khalida El-Refaei, D. Mohammad
Introduction Sarcopenia is a generalized loss of skeletal muscle mass combined with reduced strength and/or physical performance. Diabetic patients are prone to accelerated aging process, and these individuals are at increased risk of sarcopenia at an early age. Aim To determine the relationship between sarcopenia and diabetic nephropathy (DN). Patients and methods A prospective cross-sectional study was carried out on 60 patients with diabetes mellitus (DM), comprising 19 patients with DN and 41 patients without nephropathy, and 40 healthy controls. Sarcopenia was diagnosed using the European Working Group on Sarcopenia criteria. Results Of 60 patients, 44 (73%) were females and 16 (27%) were males, and their ages ranged from 31 to 70 years, with mean±SD age of 55.4±10 years. Sarcopenia was detected in nine (15%) patients with DM versus only one (2.5%) patient in healthy controls. The prevalence of sarcopenia was 35% in patients with DN versus 5% in those without DN. Skeletal muscle index was positively correlated with BMI in both sexes and in waist circumference in females. Conclusion The prevalence of sarcopenia was higher among diabetic patients with nephropathy than in those without nephropathy. Male sex and BMI are among the risk factors of sarcopenia in patients with DM.
骨骼肌减少症是骨骼肌质量的广泛性损失,并伴有力量和/或体能下降。糖尿病患者容易加速衰老过程,这些个体在早期发生肌肉减少症的风险增加。目的探讨肌肉减少症与糖尿病肾病(DN)的关系。患者与方法对60例糖尿病(DM)患者进行前瞻性横断面研究,其中DN患者19例,非肾病患者41例,健康对照40例。肌少症的诊断采用了欧洲肌少症工作组的标准。结果60例患者中,女性44例(73%),男性16例(27%),年龄31 ~ 70岁,平均±SD年龄55.4±10岁。在9例(15%)糖尿病患者中检测到肌肉减少症,而在健康对照中仅检测到1例(2.5%)患者。糖尿病肾病患者的肌肉减少率为35%,而非糖尿病肾病患者为5%。骨骼肌指数与男女BMI、女性腰围均呈正相关。结论糖尿病肾病患者肌肉减少症的发生率高于无肾病患者。男性和体重指数是糖尿病患者肌肉减少症的危险因素。
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引用次数: 0
The role of dermoscopy in the diagnosis of nail affection of psoriasis and lichen planus 皮肤镜检查在银屑病及扁平苔藓甲损诊断中的作用
Pub Date : 2022-01-01 DOI: 10.4103/sjamf.sjamf_99_21
Yara A. Kamel, Moshira Ali, Hoda El-Sebaei
Background Nail disorders comprise ∼10% of all dermatological conditions. Because diagnosis is not always possible by clinical means alone, additional diagnostic procedures may be required at times. Dermoscopy of nails (onychoscopy) has shown promising results in diagnosing various nail disorders. Aim To study the dermoscopic nail findings in psoriasis and lichen planus. Patients and methods A total of 80 patients with clinically evident psoriasis and lichen planus of nail were included in this study. They were classified into two groups: group 1 included 40 patients with nail psoriasis and group 2 included 40 patients with nail lichen planus. All patients were examined clinically and by dermoscope for criteria of psoriasis and lichen planus of the nails. Results In psoriatic patients, pitting is the commonest finding observed clinically and by dermoscope. Splinter hemorrhage, pitting, leukonychia, longitudinal ridging, oil drop sign, and onycholysis are better visualized by dermoscopy, and dilated hyponychial capillaries are detected only by dermoscopy. In patients of lichen planus, longitudinal ridging is the commonest finding observed clinically and by dermoscopy. Longitudinal ridging, pitting, chromonychia, and splinter hemorrhage are better seen by dermoscopy. Linear dyschromic bands are not detected clinically. Conclusion Onychoscopy can provide valuable diagnostic information in cases of nail psoriasis and nail lichen planus.
指甲疾病占所有皮肤病的约10%。由于仅凭临床手段诊断并不总是可能的,有时可能需要额外的诊断程序。指甲皮肤镜检查(甲镜检查)在诊断各种指甲疾病方面显示出令人鼓舞的结果。目的探讨银屑病和扁平苔藓患者的皮肤镜检查表现。患者与方法选择80例临床表现明显的银屑病伴甲扁平苔藓患者作为研究对象。将患者分为两组:1组40例甲牛皮癣患者,2组40例甲扁平苔藓患者。所有患者均接受临床检查和皮肤镜检查,以确定牛皮癣和指甲扁平苔藓的标准。结果在银屑病患者中,麻点是临床和皮肤镜下观察到的最常见的症状。刺状出血、麻点、白甲、纵向隆起、油滴征、骨膜溶解在皮镜下表现较好,支气管毛细血管扩张仅在皮镜下可见。在扁平苔藓患者中,纵向隆起是临床观察和皮肤镜检查中最常见的发现。纵向隆起、麻点、色痕和裂状出血在皮肤镜下表现较好。临床上未发现线性不平衡带。结论耳镜检查对甲癣和甲扁平苔藓有重要的诊断价值。
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引用次数: 0
Choroidal and retinal nerve fiber layer thicknesses in smokers 吸烟者脉络膜和视网膜神经纤维层厚度
Pub Date : 2022-01-01 DOI: 10.4103/sjamf.sjamf_254_21
Hagar Elgharieb, Ahmed Abdullah, Jihan A. Mohamed
Background Tobacco smoking is known for its deleterious effects on the systems of the whole body. However, the effects on the eye are not fully understood, especially the effects on the retina and choroid. Aim The current study aimed to evaluate the effects of smoking on choroidal and retinal nerve fiber layer (RNFL) thicknesses. Patients and methods The current work included 50 patients, categorized into G1 (25 healthy individuals as a control group) and G2 (25 smokers, who practiced continuous smoking for >2 years). All participants were assessed by history taking, followed by ocular examination of both eyes. The unaided and best-corrected visual acuity and intraocular pressure were determined. The slit-lamp biomicroscopic examination was performed to detect any abnormalities or media opacity of the anterior segment of the eye. It was followed by the fundus examination and optical coherence tomography to determine choroidal thickness (CT) and RNFL thickness. Results No significant differences were reported between smokers and nonsmokers regarding patient age, hemoglobin concentrations, visual acuity, or intraocular pressure. The smoking duration ranged between 3 and 30 years, and the number of daily cigarettes ranged between 5 and 30 cigarettes/day. The choroidal thickness and RNFL thickness were significantly reduced among smokers compared with nonsmokers. Finally, there was a significant, inverse correlation between CT and the smoking duration and daily smoking. Conclusion There was a significant reduction in CT and RNFL thicknesses owing to smoking. This reduction could be associated with reduced blood flow to the choroid following smoking.
吸烟对整个身体系统的有害影响是众所周知的。然而,对眼睛的影响还不完全清楚,特别是对视网膜和脉络膜的影响。目的探讨吸烟对脉络膜和视网膜神经纤维层厚度的影响。患者和方法本研究纳入50例患者,分为G1组(25例健康个体作为对照组)和G2组(25例连续吸烟2年以上的吸烟者)。所有参与者都通过记录病史进行评估,然后对双眼进行眼部检查。测定裸眼和最佳矫正视力及眼压。采用裂隙灯生物显微检查,观察眼前段有无异常或中膜混浊。随后进行眼底检查和光学相干断层扫描以确定脉络膜厚度(CT)和RNFL厚度。结果吸烟者和非吸烟者在患者年龄、血红蛋白浓度、视力或眼压方面无显著差异。吸烟时间在3到30年之间,每天吸烟的数量在5到30支/天之间。与不吸烟者相比,吸烟者的脉络膜厚度和RNFL厚度显著降低。最后,CT与吸烟持续时间和每日吸烟之间存在显著的负相关。结论吸烟可显著降低CT和RNFL厚度。这种减少可能与吸烟后脉络膜血流量减少有关。
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引用次数: 0
Immunological markers changes in pediatric immune Thrombocytopenic Purpura 儿童免疫性血小板减少性紫癜的免疫学指标变化
Pub Date : 2022-01-01 DOI: 10.4103/sjamf.sjamf_226_21
S. Hamada, Ola Al Diwany, Radwa S. Shahin
Background Individuals with immune thrombocytopenic purpura (ITP) have cellular immune responses that show the characteristics of tolerance mechanisms that have broken down. Objectives This study aimed to assess the percentage of regulatory T cells (Tregs) and CD4 lymphocytes that express CXCR6 in untreated newly diagnosed ITP in pediatric patients and their correlation with each other, the platelet (PLT) count and other PLT indices. Patients and methods A case–control study was carried out that included 40 pediatric patients with ITP, and 20 age-matched and sex-matched healthy controls were selected from Benha Children Hospital hematology clinic. Assessment of CD4+, CD25+, and FoxP3+as markers of Treg cells and also expression of the CXCR6 receptor on CD4+ T lymphocytes to evaluate the percentage of Tregs and CD4/CXCR6 +T lymphocytes were investigated by flow cytometry. Results There was a marked reduction in CD4/CXCR6 and Tregs (P=0.02 and 0.001) in the ITP group versus the control group. In contrast, there was a marked increase in CD4/CD25+cells (P=0.002) in the ITP group compared with the control group. There was a considerable reduction in the PLT count and the hemoglobin concentration in the ITP group compared with the control group (P=0.000 and 0.01), while there was a significant increase in large platelet cell ratio and platelet distribution width in the ITP group in comparison to the control group (P=0.04 for both of them); also, there were insignificant differences in total leukocytic count and mean platelet volume in the ITP group in comparison to the control group (P=0.28 and 0.77). Conclusion There was a significant decrease in the concentration of CD4+ cells that express CXCR6+ and Treg percentage in ITP patients as compared with the controls, which may explain the defect in immune self-tolerance in ITP patients.
背景:患有免疫性血小板减少性紫癜(ITP)的个体具有细胞免疫反应,显示耐受机制已经崩溃的特征。本研究旨在评估未经治疗的儿科新诊断ITP患者中表达CXCR6的调节性T细胞(Tregs)和CD4淋巴细胞的百分比及其与血小板(PLT)计数和其他PLT指标的相关性。患者与方法采用病例对照研究,选取本哈儿童医院血液科门诊40例ITP患儿和20例年龄匹配、性别匹配的健康对照。采用流式细胞术检测CD4+、CD25+、FoxP3+作为Treg细胞的标志物,以及CXCR6受体在CD4+ T淋巴细胞上的表达,评估Treg和CD4/CXCR6 +T淋巴细胞的百分比。结果与对照组相比,ITP组CD4/CXCR6和Tregs明显降低(P=0.02和0.001)。与对照组相比,ITP组CD4/CD25+细胞明显增加(P=0.002)。ITP组血小板计数和血红蛋白浓度较对照组显著降低(P=0.000和0.01),大血小板细胞比例和血小板分布宽度较对照组显著增加(P=0.04);ITP组总白细胞计数和平均血小板体积与对照组比较差异无统计学意义(P=0.28和0.77)。结论与对照组相比,ITP患者表达CXCR6+的CD4+细胞浓度和Treg百分比明显降低,这可能解释了ITP患者免疫自身耐受缺陷的原因。
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引用次数: 0
Serum midkine level as a diagnostic biomarker of hepatocellular carcinoma in Egyptian patients with chronic hepatitis C 血清midkine水平作为埃及慢性丙型肝炎患者肝细胞癌的诊断生物标志物
Pub Date : 2022-01-01 DOI: 10.4103/sjamf.sjamf_216_21
Doha AbdElaleem, S. Mohammed, O. Hendy, N. Abdelmageed
Background Early diagnosis and treatment are the keys for effective treatment of patients with hepatocellular carcinoma (HCC). The use of serological markers in patients at the highest risk of developing HCC may thus decrease HCC mortality and reduce medical costs. Midkine (MK) has an essential role in activities related to carcinogenesis such as proliferation, anti-apoptosis, transformation, migration, and angiogenesis, in many types of tumors, including HCC. Aim To evaluate serum levels of MK as a diagnostic biomarker for early detection of HCC in relation to conventional markers, such as alpha-fetoprotein (AFP). Patients and methods This study was conducted on 90 individuals who attended the Hepatogastroenterology and Infectious Diseases Department, Al-Zahraa University Hospital, Al Azhar University. The patients were divided into three groups: group I comprised 30 patients with HCC on top of hepatitis C virus and group II comprised 30 patients with cirrhotic liver post-hepatitis C virus. Control group The control group comprised 30 healthy adult participants. Results Highly statistically significant increase in serum MK in groups I and II in comparison to the control group and statistically significant increase in group I in comparison to group II. Serum MK can be used to discriminate between groups I and II at a cutoff level of more than 97.7,with 80% sensitivity, 90% specificity, 88.9% positive predictive value and 81.8% negative predictive value and area under curve=0.94. Also, it used to discriminate between groups I and III at a cutoff level of more than 76.5, with 100% sensitivity, specificity, positive predictive value, and negative predictive value with area under the curve=1.0. Conclusion MK is more accurate than AFP in diagnosing HCC, especially in detecting early stage HCC and AFP-negative HCC.
背景早期诊断和早期治疗是有效治疗肝细胞癌的关键。因此,在发生HCC风险最高的患者中使用血清学标志物可能会降低HCC死亡率并降低医疗费用。Midkine (MK)在许多类型的肿瘤(包括HCC)中具有重要的致癌作用,如增殖、抗凋亡、转化、迁移和血管生成。目的评价血清MK水平与甲胎蛋白(AFP)等常规标志物相比,作为HCC早期检测的诊断性生物标志物。患者和方法本研究对在爱资哈尔大学Al- zahraa大学医院肝胃肠病学和传染病科就诊的90名患者进行了研究。患者分为三组:第一组包括30例丙型肝炎合并HCC患者,第二组包括30例丙型肝炎合并肝硬化患者。对照组由30名健康成人组成。结果ⅰ组和ⅱ组血清MK较对照组升高有高度统计学意义,ⅰ组较ⅱ组升高有统计学意义。血清MK可用于区分I和II组,临界值大于97.7,敏感性80%,特异性90%,阳性预测值88.9%,阴性预测值81.8%,曲线下面积=0.94。在临界值大于76.5的情况下,用于区分I组和III组,具有100%的敏感性、特异性、阳性预测值和阴性预测值,曲线下面积=1.0。结论MK对肝癌的诊断准确率高于AFP,尤其对早期肝癌和AFP阴性肝癌的诊断准确率更高。
{"title":"Serum midkine level as a diagnostic biomarker of hepatocellular carcinoma in Egyptian patients with chronic hepatitis C","authors":"Doha AbdElaleem, S. Mohammed, O. Hendy, N. Abdelmageed","doi":"10.4103/sjamf.sjamf_216_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_216_21","url":null,"abstract":"Background Early diagnosis and treatment are the keys for effective treatment of patients with hepatocellular carcinoma (HCC). The use of serological markers in patients at the highest risk of developing HCC may thus decrease HCC mortality and reduce medical costs. Midkine (MK) has an essential role in activities related to carcinogenesis such as proliferation, anti-apoptosis, transformation, migration, and angiogenesis, in many types of tumors, including HCC. Aim To evaluate serum levels of MK as a diagnostic biomarker for early detection of HCC in relation to conventional markers, such as alpha-fetoprotein (AFP). Patients and methods This study was conducted on 90 individuals who attended the Hepatogastroenterology and Infectious Diseases Department, Al-Zahraa University Hospital, Al Azhar University. The patients were divided into three groups: group I comprised 30 patients with HCC on top of hepatitis C virus and group II comprised 30 patients with cirrhotic liver post-hepatitis C virus. Control group The control group comprised 30 healthy adult participants. Results Highly statistically significant increase in serum MK in groups I and II in comparison to the control group and statistically significant increase in group I in comparison to group II. Serum MK can be used to discriminate between groups I and II at a cutoff level of more than 97.7,with 80% sensitivity, 90% specificity, 88.9% positive predictive value and 81.8% negative predictive value and area under curve=0.94. Also, it used to discriminate between groups I and III at a cutoff level of more than 76.5, with 100% sensitivity, specificity, positive predictive value, and negative predictive value with area under the curve=1.0. Conclusion MK is more accurate than AFP in diagnosing HCC, especially in detecting early stage HCC and AFP-negative HCC.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81617316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of residual hip deformities secondary to Legg–Calve–Perthes disease in adults: a systematic review 成人legg - calf - perthes病继发残余髋关节畸形的处理:系统综述
Pub Date : 2022-01-01 DOI: 10.4103/sjamf.sjamf_217_21
Mohammed T Omar, A. Sultan, M. Ismail
Background The objective of this study is to systematically review the results of different studies related to the management of hip deformities secondary to Perthes’ disease in adults. Patients and methods Thirteen studies matching the inclusion and exclusion criteria, totaling 316 adults including 326 hips that underwent 119 surgical hip dislocation (SHD), 49 periacetabular osteotomy, 111 SHD with periacetabular osteotomy, 16 intertrochanteric osteotomy with acetabular roof plasty, and 31 adductor tenotomy with cheilectomy of the femoral head. Their age was in the range from 19 to 42 years with clinical follow-up range (16–135 months). The degree of pain, function, range of movements, and deformities were evaluated. Results The SHD approach has a 360° view allowing full dynamic evaluation of the hip joint, identification, and correction of the most common residual deformations, leading to functional improvement and pain relief with low complication rates. Harris hip score was a common clinical parameter in a lot of studies and showed improvement from the average range (60–68.5) before surgery to 72–95 after it. In all, 188 hips were reported to have reduction in pain at last follow-up, but adequate clinical follow-up were not available for 112 hips. However, 26 patients were reported as a failure (defined as total hip arthroplasty or persistent or increased pain). Onset osteoarthritis advancement cannot be prevented in hips. Conclusion SHD provides the opportunity to achieve any kind of simultaneous femoral and acetabular osteotomies leading to functional improvement and pain relief with low complication rates.
背景:本研究的目的是系统回顾与成人Perthes病继发髋关节畸形治疗相关的不同研究结果。患者和方法13项研究符合纳入和排除标准,共计316例成人,其中326例髋关节接受手术脱位(SHD), 49例髋臼周围截骨,111例SHD合并髋臼周围截骨,16例股骨粗隆间截骨合并髋臼顶成形术,31例内收肌腱切断术合并股骨头颧骨切除术。年龄19 ~ 42岁,临床随访16 ~ 135个月。评估疼痛程度、功能、活动范围和畸形。SHD入路具有360°的视野,可以对髋关节进行全面的动态评估,识别和纠正最常见的残余变形,从而改善功能和减轻疼痛,并发症发生率低。Harris髋关节评分是许多研究中常见的临床参数,从手术前的平均范围(60-68.5)改善到手术后的72-95。在最后一次随访中,总共有188个髋关节疼痛减轻,但112个髋关节没有得到充分的临床随访。然而,26例患者报告为失败(定义为全髋关节置换术或持续或增加的疼痛)。髋部骨关节炎的发病进展是无法预防的。结论SHD为实现任何类型的股骨和髋臼同时截骨提供了机会,可改善功能,减轻疼痛,并发症发生率低。
{"title":"Management of residual hip deformities secondary to Legg–Calve–Perthes disease in adults: a systematic review","authors":"Mohammed T Omar, A. Sultan, M. Ismail","doi":"10.4103/sjamf.sjamf_217_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_217_21","url":null,"abstract":"Background The objective of this study is to systematically review the results of different studies related to the management of hip deformities secondary to Perthes’ disease in adults. Patients and methods Thirteen studies matching the inclusion and exclusion criteria, totaling 316 adults including 326 hips that underwent 119 surgical hip dislocation (SHD), 49 periacetabular osteotomy, 111 SHD with periacetabular osteotomy, 16 intertrochanteric osteotomy with acetabular roof plasty, and 31 adductor tenotomy with cheilectomy of the femoral head. Their age was in the range from 19 to 42 years with clinical follow-up range (16–135 months). The degree of pain, function, range of movements, and deformities were evaluated. Results The SHD approach has a 360° view allowing full dynamic evaluation of the hip joint, identification, and correction of the most common residual deformations, leading to functional improvement and pain relief with low complication rates. Harris hip score was a common clinical parameter in a lot of studies and showed improvement from the average range (60–68.5) before surgery to 72–95 after it. In all, 188 hips were reported to have reduction in pain at last follow-up, but adequate clinical follow-up were not available for 112 hips. However, 26 patients were reported as a failure (defined as total hip arthroplasty or persistent or increased pain). Onset osteoarthritis advancement cannot be prevented in hips. Conclusion SHD provides the opportunity to achieve any kind of simultaneous femoral and acetabular osteotomies leading to functional improvement and pain relief with low complication rates.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88794137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual assessment after cataract surgery 白内障手术后视力评估
Pub Date : 2021-10-01 DOI: 10.4103/sjamf.sjamf_144_21
Asmaa Abd-Elhady Ibrahim, Hanan El Ghoneimy, Afaf H. Rashwan
Background Cataract surgery has been one of the most commonly performed surgical procedures worldwide. Cataract extraction is indicated for poor visual acuity. Daily life visual problems such as cataract affect both far and near vision. Aim The aim of this study was visual assessment of patients after cataract surgery. Patients and methods This is a descriptive prospective study of consecutive patients undergoing cataract surgery at Memorial Institute of Ophthalmic Research between 2019 and 2020. A total of 50 eyes that met the inclusion criteria were included. Patients were examined preoperative, first day, 1 week, 1 month, and 3 months postoperatively. Results The mean age was 61.82±7.6 years, and the male to female ratio was 1.1 : 1. Preoperatively, 13 (26%) patients were blind in the operated eye, whereas 37 (74%) patients had moderate to severe visual impairment. On the first day postoperatively, 13 (26%) patients had visual acuity of 6/6–6/18. Regarding best-corrected vision after refraction 3 months postoperatively, 32 (64%) of 50 patients had good vision, whereas 18 (36%) patients had borderline vision, and no patients (0%) had poor vision after refraction. Conclusion Cataract surgery is a cost-effective surgery but is considered a huge burden. Even with great efforts, multiple factors affect the surgical success and the outcomes, including surgery-related factors, surgeon, and patient-related factors. As cataract surgery is a cost effective surgery, in this study the aim is to get high benefits from this cost.
白内障手术是世界范围内最常见的外科手术之一。白内障摘除适用于视力不佳的患者。日常生活中的视力问题,如白内障,会影响远近视力。目的对白内障术后患者进行视力评估。这是一项描述性前瞻性研究,研究对象为2019 - 2020年在纪念眼科研究所连续接受白内障手术的患者。共纳入50只符合纳入标准的眼睛。术前、术后第一天、术后1周、术后1个月、术后3个月对患者进行检查。结果患者平均年龄61.82±7.6岁,男女比例为1.1:1。术前手术眼失明13例(26%),中度至重度视力损害37例(74%)。术后第一天,13例(26%)患者视力为6/6 ~ 6/18。50例患者术后3个月最佳矫正视力,32例(64%)患者视力良好,18例(36%)患者视力边缘,无一例(0%)患者屈光后视力不良。结论白内障手术是一种经济有效的手术,但被认为是一种巨大的负担。尽管付出了很大的努力,但影响手术成功和结果的因素是多方面的,包括手术相关因素、外科医生和患者相关因素。由于白内障手术是一种成本效益高的手术,本研究的目的是从这种成本中获得较高的收益。
{"title":"Visual assessment after cataract surgery","authors":"Asmaa Abd-Elhady Ibrahim, Hanan El Ghoneimy, Afaf H. Rashwan","doi":"10.4103/sjamf.sjamf_144_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_144_21","url":null,"abstract":"Background Cataract surgery has been one of the most commonly performed surgical procedures worldwide. Cataract extraction is indicated for poor visual acuity. Daily life visual problems such as cataract affect both far and near vision. Aim The aim of this study was visual assessment of patients after cataract surgery. Patients and methods This is a descriptive prospective study of consecutive patients undergoing cataract surgery at Memorial Institute of Ophthalmic Research between 2019 and 2020. A total of 50 eyes that met the inclusion criteria were included. Patients were examined preoperative, first day, 1 week, 1 month, and 3 months postoperatively. Results The mean age was 61.82±7.6 years, and the male to female ratio was 1.1 : 1. Preoperatively, 13 (26%) patients were blind in the operated eye, whereas 37 (74%) patients had moderate to severe visual impairment. On the first day postoperatively, 13 (26%) patients had visual acuity of 6/6–6/18. Regarding best-corrected vision after refraction 3 months postoperatively, 32 (64%) of 50 patients had good vision, whereas 18 (36%) patients had borderline vision, and no patients (0%) had poor vision after refraction. Conclusion Cataract surgery is a cost-effective surgery but is considered a huge burden. Even with great efforts, multiple factors affect the surgical success and the outcomes, including surgery-related factors, surgeon, and patient-related factors. As cataract surgery is a cost effective surgery, in this study the aim is to get high benefits from this cost.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72775441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Premenstrual tension in medical students: risk factors, lifestyle, and effect on quality of life 医学生经前紧张:危险因素、生活方式及其对生活质量的影响
Pub Date : 2021-10-01 DOI: 10.4103/sjamf.sjamf_148_21
Sahar Saleh, S. El-Mallah, S. Hammouda, Doaa M. Saleh
Background Premenstrual syndrome (PMS) comprises physical, mental, and psychological symptoms that occur for some women during the late luteal phase of their menstrual period about 7 days before menstruation. Aim and objectives The aim of this study was to investigate the prevalence and characteristics of PSM/premenstrual dysphoric disorder, associated risk factors, and effect on quality of life in medical students. Patients and methods This cross-sectional study was carried out at the Department of Obstetrics and Gynecology, Faculty of Medicine for Girls, Al Azhar University, during the period from August 2020 to February 2021 and included 800 medical students. All students were invited to fill a self-evaluation questionnaire that included five sections: sociodemographic and general medical data, gynecological and obstetric data, lifestyle and special habits, and PMSs. Results PMS was found in 59.7% of those students. Statistically significant associations were found between lifestyle risk factors and presence and severity of PMS, and PMS was found to result in significant interference with daily life. Conclusion PMS is a common disorder among medical students that adversely affects their quality of life.
经前综合征(PMS)包括生理、精神和心理上的症状,这些症状发生在月经期的黄体晚期,大约在月经前7天。目的探讨医学生经前焦虑症(PSM)的患病率、特点、相关危险因素及其对生活质量的影响。患者和方法本横断面研究于2020年8月至2021年2月在爱资哈尔大学女子医学院妇产科进行,包括800名医学生。所有学生都被邀请填写一份自我评估问卷,其中包括五个部分:社会人口统计和一般医疗数据、妇科和产科数据、生活方式和特殊习惯,以及经前综合症。结果经前综合症发生率为59.7%。统计上发现,生活方式风险因素与经前综合症的存在和严重程度之间存在显著关联,经前综合症对日常生活造成显著干扰。结论经前症候群是医学生的常见病,严重影响了医学生的生活质量。
{"title":"Premenstrual tension in medical students: risk factors, lifestyle, and effect on quality of life","authors":"Sahar Saleh, S. El-Mallah, S. Hammouda, Doaa M. Saleh","doi":"10.4103/sjamf.sjamf_148_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_148_21","url":null,"abstract":"Background Premenstrual syndrome (PMS) comprises physical, mental, and psychological symptoms that occur for some women during the late luteal phase of their menstrual period about 7 days before menstruation. Aim and objectives The aim of this study was to investigate the prevalence and characteristics of PSM/premenstrual dysphoric disorder, associated risk factors, and effect on quality of life in medical students. Patients and methods This cross-sectional study was carried out at the Department of Obstetrics and Gynecology, Faculty of Medicine for Girls, Al Azhar University, during the period from August 2020 to February 2021 and included 800 medical students. All students were invited to fill a self-evaluation questionnaire that included five sections: sociodemographic and general medical data, gynecological and obstetric data, lifestyle and special habits, and PMSs. Results PMS was found in 59.7% of those students. Statistically significant associations were found between lifestyle risk factors and presence and severity of PMS, and PMS was found to result in significant interference with daily life. Conclusion PMS is a common disorder among medical students that adversely affects their quality of life.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73621593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound and diffusion MRI in evaluation of ovarian lesions 超声和弥散性MRI对卵巢病变的评价
Pub Date : 2021-10-01 DOI: 10.4103/sjamf.sjamf_176_21
M. Hamed, A. Aborashed, Hanaa Abo Ria, M. Tawfik
Objective The aim of this study was to evaluate the role of ultrasound (US) and diffusion MRI in the diagnosis of ovarian lesions. Patients and methods This prospective study will include 50 patients with different types of ovarian lesions referred to the Radiology Department at El-Zahra Hospital for performing US, color Doppler assessment, and/or diffusion MRI, the study was conducted for a period of 1 year from March 2020 to March 2021. Results In total, 50 different lesions were found. The most frequent lesions were the cystic lesions septated, vegetated, or not. Conclusion US and color Doppler were found to be useful in differentiating a benign from a malignant adnexal mass. MRI has shown to be beneficial in confirmation of adnexal masses in problematic cases.
目的探讨超声(US)和弥散磁共振成像(弥散MRI)在卵巢病变诊断中的作用。患者和方法本前瞻性研究将纳入El-Zahra医院放射科进行超声、彩色多普勒评估和/或弥散MRI检查的50例不同类型卵巢病变患者,研究时间为1年,从2020年3月至2021年3月。结果共发现50种不同的病变。最常见的病变是囊性病变分离,植被,或没有。结论超声和彩色多普勒超声对鉴别附件肿块的良恶性有一定的价值。MRI已被证明是有益的确认附件肿块在有问题的情况下。
{"title":"Ultrasound and diffusion MRI in evaluation of ovarian lesions","authors":"M. Hamed, A. Aborashed, Hanaa Abo Ria, M. Tawfik","doi":"10.4103/sjamf.sjamf_176_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_176_21","url":null,"abstract":"Objective The aim of this study was to evaluate the role of ultrasound (US) and diffusion MRI in the diagnosis of ovarian lesions. Patients and methods This prospective study will include 50 patients with different types of ovarian lesions referred to the Radiology Department at El-Zahra Hospital for performing US, color Doppler assessment, and/or diffusion MRI, the study was conducted for a period of 1 year from March 2020 to March 2021. Results In total, 50 different lesions were found. The most frequent lesions were the cystic lesions septated, vegetated, or not. Conclusion US and color Doppler were found to be useful in differentiating a benign from a malignant adnexal mass. MRI has shown to be beneficial in confirmation of adnexal masses in problematic cases.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78021267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparative study of preoperative misoprostol versus intraoperative pericervical hemostatic tourniquet in reducing blood loss in cases of myomectomy 术前米索前列醇与术中颈周止血止血带减少子宫肌瘤切除术出血量的比较研究
Pub Date : 2021-10-01 DOI: 10.4103/sjamf.sjamf_145_21
Asraa Ahmed Alhameedi, Amal Aboseef, Doaa Efaat
Objective The aim was to compare preoperative vaginal misoprostol versus intraoperative per-cervical hemostatic tourniquet in reducing blood loss during myomectomy. Patients and methods This prospective randomized control study was conducted on 60 patients who were experiencing symptomatic uterine myoma and underwent abdominal myomectomy at the Obstetrics and Gynecology Department of Al-Zahraa University Hospital from August 2020 to February 2021. The patients were divided into two groups: group A (misoprostol group) included 30 women who received 400 mg misoprostol vaginally 1 h before myomectomy operation, and group B (tourniquet group) included 30 women who underwent intraoperative per-cervical infant feeding tube form of tourniquet, during myomectomy. The intraoperative comments on type, site, size of fibroid, operation time, amount of blood loss, and blood transfusion need were recorded. The main outcome measures were as follows: primary outcome included the estimated blood loss and postoperative hemoglobin (Hb) and hematocrit (HCT) level, and secondary outcome included the possibility of blood transfusion and operative time. Results There was a significantly shorter duration of operation in tourniquet group (47.5±4.7) compared with misoprostol group (53.0±6.9) (P=0.001). There was significant less blood loss in the tourniquet group compared with the misoprostol group (375.0±96.3 and 440±78, respectively) (P=0.006). There was a statistically significant difference between the studied groups regarding blood transfusion, as eight patients (26.7%) of misoprostol group received blood transfusion, whereas only two patients (6.7%) of tourniquet group received blood transfusion (P=0.038). There was insignificant difference in baseline (preoperative) Hb and HCT levels between the study groups. However, there was a statistically significant difference between the study groups regarding the postoperative Hb and HCT, which were higher in the tourniquet group compared with the misoprostol group (33.7±2.6 and 32.2±2.4, respectively; P=0.033). Conclusion Fastening a tourniquet at per-cervical area during abdominal myomectomy reduced the intraoperative blood loss significantly compared with preoperative misoprostol, with shorter operative time with decreased incidence of risk of blood transfusion.
目的比较术前阴道米索前列醇与术中宫颈止血止血带在子宫肌瘤切除术中减少出血量的效果。患者和方法本前瞻性随机对照研究于2020年8月至2021年2月在Al-Zahraa大学医院妇产科进行了60例有症状的子宫肌瘤和腹部子宫肌瘤切除术的患者。患者分为两组:A组(米索前列醇组)包括30名妇女,她们在子宫肌瘤切除术前1小时阴道接受400 mg米索前列醇;B组(止血带组)包括30名妇女,她们在子宫肌瘤切除术期间接受术中经宫颈婴儿喂养管形式的止血带。记录术中对肌瘤的类型、部位、大小、手术时间、出血量、输血需水量的评价。主要观察指标如下:主要观察指标包括估计失血量和术后血红蛋白(Hb)和红细胞压积(HCT)水平,次要观察指标包括输血可能性和手术时间。结果止血带组手术时间(47.5±4.7)明显短于米索前列醇组(53.0±6.9)(P=0.001)。止血带组出血量明显少于米索前列醇组(分别为375.0±96.3和440±78)(P=0.006)。两组输血比较差异有统计学意义,米索前列醇组输血8例(26.7%),止血带组输血2例(6.7%),差异有统计学意义(P=0.038)。各组间基线(术前)Hb和HCT水平差异不显著。然而,两组术后Hb和HCT差异有统计学意义,止血带组高于米索前列醇组(分别为33.7±2.6和32.2±2.4);P = 0.033)。结论与术前使用米索前列醇相比,在子宫肌瘤切除术中经颈处系上止血带可显著减少术中出血量,缩短手术时间,降低输血风险。
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引用次数: 1
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The Scientific Journal of Al-Azhar Medical Faculty, Girls
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