Pub Date : 2021-10-01DOI: 10.4103/sjamf.sjamf_198_21
Riham AbdelAal Mohamed, A. Yassen, Abdullah Ahmed
Background Digital breast tomosynthesis (DBT) has been developed to improve the detection and characterization of breast lesions and to overcome the limitations of digital mammography. The aim of this work was to highlight the value of DBT in evaluation of suspicious solid breast lesions in comparison with mammography and ultrasonography in patients over 30 years old. Patients and methods This prospective study included a total of 50 females who had 54 suspicious solid breast lesions, and all patients were evaluated by mammography, tomosynthesis, and ultrasound. Their age ranging from 30 to 90 years old with mean age±SD was 58.8±12.7 years. All radiological findings were compared with the final histopathology diagnosis, which was the gold standard for our study. Results The sensitivity of tomosynthesis was 96%, the specificity was 75%, the positive predictive value (PPV) was 98%, the negative predictive value (NPV) was 60%, and the accuracy was 94%. While the sensitivity of digital mammography was 92%, the specificity was 50%, the PPV was 95%, the NPV was 33%, and the accuracy was 88%. Breast ultrasound showed the highest sensitivity in our study where the sensitivity of ultrasound was 98%, the specificity was 100%, the PPV was 100%, the NPV was 80%, and the accuracy was 98%. Conclusion DBT technique can improve the clinical performance of mammography by increasing the sensitivity and specificity. It overcomes the limitation of mammography caused by tissue overlapping. Thus, it can provide better tissue visualization by its characteristic capability of producing three-dimensional nonoverlapped tissue information.
{"title":"The role of tomosynthesis in evaluation of suspicious solid breast lesion in comparison with mammography and ultrasonography in patients over 30 years old","authors":"Riham AbdelAal Mohamed, A. Yassen, Abdullah Ahmed","doi":"10.4103/sjamf.sjamf_198_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_198_21","url":null,"abstract":"Background Digital breast tomosynthesis (DBT) has been developed to improve the detection and characterization of breast lesions and to overcome the limitations of digital mammography. The aim of this work was to highlight the value of DBT in evaluation of suspicious solid breast lesions in comparison with mammography and ultrasonography in patients over 30 years old. Patients and methods This prospective study included a total of 50 females who had 54 suspicious solid breast lesions, and all patients were evaluated by mammography, tomosynthesis, and ultrasound. Their age ranging from 30 to 90 years old with mean age±SD was 58.8±12.7 years. All radiological findings were compared with the final histopathology diagnosis, which was the gold standard for our study. Results The sensitivity of tomosynthesis was 96%, the specificity was 75%, the positive predictive value (PPV) was 98%, the negative predictive value (NPV) was 60%, and the accuracy was 94%. While the sensitivity of digital mammography was 92%, the specificity was 50%, the PPV was 95%, the NPV was 33%, and the accuracy was 88%. Breast ultrasound showed the highest sensitivity in our study where the sensitivity of ultrasound was 98%, the specificity was 100%, the PPV was 100%, the NPV was 80%, and the accuracy was 98%. Conclusion DBT technique can improve the clinical performance of mammography by increasing the sensitivity and specificity. It overcomes the limitation of mammography caused by tissue overlapping. Thus, it can provide better tissue visualization by its characteristic capability of producing three-dimensional nonoverlapped tissue information.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85273037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.4103/sjamf.sjamf_152_21
A. Shehab, Abd-Elhafiz Shehab-Eldien, M. Elhendawy, Mariam Ghanem
Introduction Brain tumors represent an important cause of morbidity and mortality, and some cases are frequently difficult to treat. However, development of noninvasive imaging techniques like MRI/magnetic resonance spectroscopy has improved the diagnostic accuracy. Aim Stereotactic biopsy was performed for tissue diagnosis. Patients and methods A total of 50 patients with deep-seated brain lesions, at eloquent area or multiple brain lesions, by MRI study, were biopsied using frame and frameless stereotactic procedures between the periods of September 2016 and October 2019. Results During the study period, our diagnostic yield was 94.0%. Conclusion Either frame or frameless stereotactic biopsy is a minimal invasive method for accurate diagnosis in deep-seated brain lesions.
{"title":"Stereotactic biopsy in brain lesions not amenable to microsurgery","authors":"A. Shehab, Abd-Elhafiz Shehab-Eldien, M. Elhendawy, Mariam Ghanem","doi":"10.4103/sjamf.sjamf_152_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_152_21","url":null,"abstract":"Introduction Brain tumors represent an important cause of morbidity and mortality, and some cases are frequently difficult to treat. However, development of noninvasive imaging techniques like MRI/magnetic resonance spectroscopy has improved the diagnostic accuracy. Aim Stereotactic biopsy was performed for tissue diagnosis. Patients and methods A total of 50 patients with deep-seated brain lesions, at eloquent area or multiple brain lesions, by MRI study, were biopsied using frame and frameless stereotactic procedures between the periods of September 2016 and October 2019. Results During the study period, our diagnostic yield was 94.0%. Conclusion Either frame or frameless stereotactic biopsy is a minimal invasive method for accurate diagnosis in deep-seated brain lesions.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79322302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.4103/sjamf.sjamf_157_21
A. Yosri, Gasser Al-Shyal, A. Shehab
Background Lumbosacral spondylolisthesis is a common pathology characterized by single or multilevel slippage of lumbar vertebra over the other and may be associated with spinal canal stenosis and neural foramina compromise and may present with lower back pain, radicular pain, or neurogenic claudication pain. The current study aimed to compare the short-term clinical outcomes of two surgical fusion techniques in the management of this pathology Patients and methods A total of 40 patients with lumbosacral spondylolisthesis were included in this study. Patients were randomly divided into two groups according to the surgical approach and fixation technique used in the management. Group A was operated by posterior lumbar decompression, transpedicular screw fixation, and posterolateral intertransverse bony fusion. Group B was operated by posterior decompression, transpedicular screw, and posterolateral intertransverse bony fusion associated with interbody fusion by insertion of interbody cages. Results Statistical significance was reached in the duration of surgery, blood loss, and postoperative fusion rates, but there was no significant difference between the two groups regarding intraoperative or postoperative complication rates, clinical outcome, and patient satisfaction. Conclusion The application of the lumbar interbody cage with posterolateral intertransverse fusion proved to have better fusion rates, but still intertransverse bony fusion alone gives the same results regarding patient satisfaction and postoperative clinical improvement with shorter operative time.
{"title":"Comparative study of transpediculer screw fixation and intertransverse fusion with and without interbody cage insertion in management of lumbosacral spondylolisthesis","authors":"A. Yosri, Gasser Al-Shyal, A. Shehab","doi":"10.4103/sjamf.sjamf_157_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_157_21","url":null,"abstract":"Background Lumbosacral spondylolisthesis is a common pathology characterized by single or multilevel slippage of lumbar vertebra over the other and may be associated with spinal canal stenosis and neural foramina compromise and may present with lower back pain, radicular pain, or neurogenic claudication pain. The current study aimed to compare the short-term clinical outcomes of two surgical fusion techniques in the management of this pathology Patients and methods A total of 40 patients with lumbosacral spondylolisthesis were included in this study. Patients were randomly divided into two groups according to the surgical approach and fixation technique used in the management. Group A was operated by posterior lumbar decompression, transpedicular screw fixation, and posterolateral intertransverse bony fusion. Group B was operated by posterior decompression, transpedicular screw, and posterolateral intertransverse bony fusion associated with interbody fusion by insertion of interbody cages. Results Statistical significance was reached in the duration of surgery, blood loss, and postoperative fusion rates, but there was no significant difference between the two groups regarding intraoperative or postoperative complication rates, clinical outcome, and patient satisfaction. Conclusion The application of the lumbar interbody cage with posterolateral intertransverse fusion proved to have better fusion rates, but still intertransverse bony fusion alone gives the same results regarding patient satisfaction and postoperative clinical improvement with shorter operative time.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81508623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.4103/sjamf.sjamf_182_21
A. Ahmed, M. Hanafy, Doaa M. Saleh
Background Although urinary incontinence (UI) is not a life-threatening disorder, it has been shown to have detrimental effects on quality of life in terms of psychological and social, associated with negative effects on women’s sexuality. Aim and objectives To estimate the prevalence and assess risk factors of UI among premenopausal and postmenopausal females. Patients and methods A cross-sectional study was carried out at gynecological and urological outpatient clinics at Al-Zahraa University Hospital and Kafr El-Sheikh General Hospital, on 1000 females with their ages ranging from 40 to 70 after taking informed consent from all participants, from August 2020 to January 2021. Results There was statistically significant increased parity (three times or more), normal delivery with episiotomy in stress UI. Also, there were statistically significant increased delivery complications and BMI in urge UI and there was statistically significant increased menopause and age in mixed UI. Conclusion The present study showed a moderate prevalence of urine incontinence between females. The associated risk factors of urine incontinence were older age, obesity, menopause, using of instruments (forceps and ventuse), high parity, and normal delivery with episiotomy; also, we found that cesarean delivery has a protective role for UI. The quality of daily life was affected more negatively in women with UI.
{"title":"Prevalence and risk factors of urinary incontinence among premenopausal and postmenopausal females","authors":"A. Ahmed, M. Hanafy, Doaa M. Saleh","doi":"10.4103/sjamf.sjamf_182_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_182_21","url":null,"abstract":"Background Although urinary incontinence (UI) is not a life-threatening disorder, it has been shown to have detrimental effects on quality of life in terms of psychological and social, associated with negative effects on women’s sexuality. Aim and objectives To estimate the prevalence and assess risk factors of UI among premenopausal and postmenopausal females. Patients and methods A cross-sectional study was carried out at gynecological and urological outpatient clinics at Al-Zahraa University Hospital and Kafr El-Sheikh General Hospital, on 1000 females with their ages ranging from 40 to 70 after taking informed consent from all participants, from August 2020 to January 2021. Results There was statistically significant increased parity (three times or more), normal delivery with episiotomy in stress UI. Also, there were statistically significant increased delivery complications and BMI in urge UI and there was statistically significant increased menopause and age in mixed UI. Conclusion The present study showed a moderate prevalence of urine incontinence between females. The associated risk factors of urine incontinence were older age, obesity, menopause, using of instruments (forceps and ventuse), high parity, and normal delivery with episiotomy; also, we found that cesarean delivery has a protective role for UI. The quality of daily life was affected more negatively in women with UI.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89495830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.4103/sjamf.sjamf_171_21
Rana Elkarray, R. Mohamed, Rania A. Hamed
Background Epilepsy is among the most common neurological disorder in childhood for which there is substantial evidence of the associated psychopathology. Objective To assess the prevalence of behavioral problems in children with epilepsy and its risk factors. Patients and methods Fifty patients aged 5–16 years with a diagnosis of epilepsy and 50 control children of the same age range were recruited. A validated Arabic version of the Mini International Neuropsychiatric Interview for Children and Adolescents in addition to the Child Behavior Check List was applied to evaluate the sample. Results By using Mini International Neuropsychiatric Interview for Children and Adolescents, it was found that both conduct disorder and anxiety show a statistically significant difference between the epileptic and control groups. According to Child Behavior Check List, it was found that the epileptic group had clinically attention problems, rule-breaking behavior, aggressive behavior, and social problems compared with the nonepileptic group. Regarding the mean values, behavioral scores in patients with epilepsy were significantly higher as compared with control in all the domains, except rule-breaking complaints and thought problems. Some factors were significantly associated with neuropsychiatric comorbidities in children with epilepsy as seizure duration more than or equal to 5 years, polytherapy, and uncontrolled seizure-status epilepsy type (primary generalized epilepsy). Conclusion Children with epilepsy are more likely to develop neuropsychiatric problems. Early detection, diagnosis, and treatment of neuropsychiatric comorbidities may enhance their long-term prognosis.
{"title":"Prevalence of psychiatric and behavioral comorbidities in pediatric epilepsy","authors":"Rana Elkarray, R. Mohamed, Rania A. Hamed","doi":"10.4103/sjamf.sjamf_171_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_171_21","url":null,"abstract":"Background Epilepsy is among the most common neurological disorder in childhood for which there is substantial evidence of the associated psychopathology. Objective To assess the prevalence of behavioral problems in children with epilepsy and its risk factors. Patients and methods Fifty patients aged 5–16 years with a diagnosis of epilepsy and 50 control children of the same age range were recruited. A validated Arabic version of the Mini International Neuropsychiatric Interview for Children and Adolescents in addition to the Child Behavior Check List was applied to evaluate the sample. Results By using Mini International Neuropsychiatric Interview for Children and Adolescents, it was found that both conduct disorder and anxiety show a statistically significant difference between the epileptic and control groups. According to Child Behavior Check List, it was found that the epileptic group had clinically attention problems, rule-breaking behavior, aggressive behavior, and social problems compared with the nonepileptic group. Regarding the mean values, behavioral scores in patients with epilepsy were significantly higher as compared with control in all the domains, except rule-breaking complaints and thought problems. Some factors were significantly associated with neuropsychiatric comorbidities in children with epilepsy as seizure duration more than or equal to 5 years, polytherapy, and uncontrolled seizure-status epilepsy type (primary generalized epilepsy). Conclusion Children with epilepsy are more likely to develop neuropsychiatric problems. Early detection, diagnosis, and treatment of neuropsychiatric comorbidities may enhance their long-term prognosis.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87716263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.4103/sjamf.sjamf_164_21
Rania El-Abeady, Soad Elsawy, Marwa Ali Abd El-Rahim
Introduction Rheumatoid arthritis (RA) is an autoimmune disease characterized by articular and extra-articular structures. Carpal tunnel syndrome (CTS) is one of the most frequent extra-articular manifestations of RA. Aim To detect the prevalence of CTS in patients with RA and the accuracy of ultrasonography (US) in comparison with nerve conduction study (NCS). Patients and methods This was a case–control study carried out at Al-Zahraa University Hospital. It was conducted on 50 patients with RA and 30 controls. They were evaluated by history taking, clinical evaluation, assessment of RA disease activity by disease activity score 28, disability by Health Assessment Questionnaire, functional status by the Boston Questionnaire, bilateral median (MN) NCS, and US, which was used for cross-sectional area and flat ratio of the median nerve at different levels of carpal tunnel and examination of other carpal tunnel contents. Results CTS was diagnosed in 27% of the patients with RA by US and 20% by NCS. There was a highly significant difference between the patients with RA and control groups regarding cross-sectional area and flat ratio of the transverse scan of the MN at three different levels (P<0.07 and 0.001). There was a positive relation between the outcome of US and the NCS in the diagnosis of CTS in patients with RA (P<0.001). Conclusion US has the advantage of early detection of CTS and can assess the morphology of MN and its surroundings.
{"title":"Prevalence of carpal tunnel syndrome in patients with rheumatoid arthritis by ultrasonographic and electrodiagnostic studies","authors":"Rania El-Abeady, Soad Elsawy, Marwa Ali Abd El-Rahim","doi":"10.4103/sjamf.sjamf_164_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_164_21","url":null,"abstract":"Introduction Rheumatoid arthritis (RA) is an autoimmune disease characterized by articular and extra-articular structures. Carpal tunnel syndrome (CTS) is one of the most frequent extra-articular manifestations of RA. Aim To detect the prevalence of CTS in patients with RA and the accuracy of ultrasonography (US) in comparison with nerve conduction study (NCS). Patients and methods This was a case–control study carried out at Al-Zahraa University Hospital. It was conducted on 50 patients with RA and 30 controls. They were evaluated by history taking, clinical evaluation, assessment of RA disease activity by disease activity score 28, disability by Health Assessment Questionnaire, functional status by the Boston Questionnaire, bilateral median (MN) NCS, and US, which was used for cross-sectional area and flat ratio of the median nerve at different levels of carpal tunnel and examination of other carpal tunnel contents. Results CTS was diagnosed in 27% of the patients with RA by US and 20% by NCS. There was a highly significant difference between the patients with RA and control groups regarding cross-sectional area and flat ratio of the transverse scan of the MN at three different levels (P<0.07 and 0.001). There was a positive relation between the outcome of US and the NCS in the diagnosis of CTS in patients with RA (P<0.001). Conclusion US has the advantage of early detection of CTS and can assess the morphology of MN and its surroundings.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81706865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.4103/sjamf.sjamf_160_21
Nouralhuda A. Hassan, Hosneya A Mohamed, M. Helal
Background Breast cancer is the most commonly diagnosed malignancy in women worldwide. Aims To assess the diagnostic accuracy of automated breast ultrasound (ABUS) in comparison with other different breast imaging modalities in evaluation of breast lesions and correlate the findings with the pathology results. Patients and methods A prospective analytical study included 50 breast lesions in 50 patients (age: 32–79 years; mean age: 46.8 years). All patients underwent digital mammography (MX), tomosynthesis, contrast-enhanced digital mammography (CEDM), and then ABUS. The results of ABUS were compared with breast imaging modalities. The findings were correlated with final pathological results, which served as the reference standard. Results Overall, 30% (15/50) of the lesions were histopathologically proven as benign lesions, and 70% (35/50) were malignant. Of the 35 malignant lesions, 33 were detectable by ABUS in comparison with 13 of 15 benign lesions. ABUS showed a diagnostic accuracy of 92%, whereas MX showed 70%, tomosynthesis 82%, and CEDM 96%. ABUS improved the sensitivity to 94.4%, with better positive and negative predictive values (positive predictive value of about 94.3% and negative predictive value of 86.7%) Conclusion ABUS added value as an adjunct in the detection and characterization of indeterminate breast lesions during routine imaging diagnosis compared with MX, tomosynthesis, or CEDM. It is valuable in increased accuracy of BIRADS assessment of lesions, regional extension, and multicentric and multifocal breast lesions.
{"title":"Diagnostic accuracy of automated breast ultrasound in comparison with different breast imaging modalities in evaluation of breast lesions","authors":"Nouralhuda A. Hassan, Hosneya A Mohamed, M. Helal","doi":"10.4103/sjamf.sjamf_160_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_160_21","url":null,"abstract":"Background Breast cancer is the most commonly diagnosed malignancy in women worldwide. Aims To assess the diagnostic accuracy of automated breast ultrasound (ABUS) in comparison with other different breast imaging modalities in evaluation of breast lesions and correlate the findings with the pathology results. Patients and methods A prospective analytical study included 50 breast lesions in 50 patients (age: 32–79 years; mean age: 46.8 years). All patients underwent digital mammography (MX), tomosynthesis, contrast-enhanced digital mammography (CEDM), and then ABUS. The results of ABUS were compared with breast imaging modalities. The findings were correlated with final pathological results, which served as the reference standard. Results Overall, 30% (15/50) of the lesions were histopathologically proven as benign lesions, and 70% (35/50) were malignant. Of the 35 malignant lesions, 33 were detectable by ABUS in comparison with 13 of 15 benign lesions. ABUS showed a diagnostic accuracy of 92%, whereas MX showed 70%, tomosynthesis 82%, and CEDM 96%. ABUS improved the sensitivity to 94.4%, with better positive and negative predictive values (positive predictive value of about 94.3% and negative predictive value of 86.7%) Conclusion ABUS added value as an adjunct in the detection and characterization of indeterminate breast lesions during routine imaging diagnosis compared with MX, tomosynthesis, or CEDM. It is valuable in increased accuracy of BIRADS assessment of lesions, regional extension, and multicentric and multifocal breast lesions.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83882080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.4103/sjamf.sjamf_193_21
I. Mohammad, Wafaa Mahmoud, Hala S A Hafiz
Background Seborrheic keratoses (SKs) are very common benign epithelial skin tumors. So, there is a significant need for a safe, effective, noninvasive, and cosmetically acceptable treatment for this common condition. Aim To evaluate the effect of different concentrations of hydrogen peroxide (HP)-based topical solution (10 and 30%) for the treatment of SK lesions. Patients and methods Fifty patients aged 40–77 years, with SK lesions, were enrolled in this study and were divided randomly and equally into two groups: group 1 included 25 patients who underwent four sessions of topical HP 10% solution at 3-week interval and group 2 included 25 patients who underwent four sessions of topical HP 30% solution at 3-week interval. The lesions were evaluated clinically by study-assessment scale, dermoscopic findings before and after treatment, and patient’s self-assessment. Results At the end of the study, there was a statistically insignificant difference in the clinical grade of SK lesions before and after treatment in both groups: group 1 (P=1.000) and group 2 (P=0.598). Also, there was a statistically insignificant difference between dermoscopic pictures before and after treatment. There was a statistically insignificant difference between the improvements in both groups denoting that both concentrations gave similar net results. Conclusion Topical 10 and 30% of HP solutions are not effective in the treatment of SKs with no significant side effects.
{"title":"Effect of topical hydrogen peroxide in treatment of seborrheic keratosis","authors":"I. Mohammad, Wafaa Mahmoud, Hala S A Hafiz","doi":"10.4103/sjamf.sjamf_193_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_193_21","url":null,"abstract":"Background Seborrheic keratoses (SKs) are very common benign epithelial skin tumors. So, there is a significant need for a safe, effective, noninvasive, and cosmetically acceptable treatment for this common condition. Aim To evaluate the effect of different concentrations of hydrogen peroxide (HP)-based topical solution (10 and 30%) for the treatment of SK lesions. Patients and methods Fifty patients aged 40–77 years, with SK lesions, were enrolled in this study and were divided randomly and equally into two groups: group 1 included 25 patients who underwent four sessions of topical HP 10% solution at 3-week interval and group 2 included 25 patients who underwent four sessions of topical HP 30% solution at 3-week interval. The lesions were evaluated clinically by study-assessment scale, dermoscopic findings before and after treatment, and patient’s self-assessment. Results At the end of the study, there was a statistically insignificant difference in the clinical grade of SK lesions before and after treatment in both groups: group 1 (P=1.000) and group 2 (P=0.598). Also, there was a statistically insignificant difference between dermoscopic pictures before and after treatment. There was a statistically insignificant difference between the improvements in both groups denoting that both concentrations gave similar net results. Conclusion Topical 10 and 30% of HP solutions are not effective in the treatment of SKs with no significant side effects.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86538200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.4103/sjamf.sjamf_35_21
Sahar Gamman, Fatma Hammad, Waleed A. Taha, Osama Bakheet, I. Ahmad
Background Chronic kidney disease (CKD) arises from many heterogeneous disease pathways that alter the function and structure of the kidney irreversibly, over months or years. The diagnosis of CKD rests on establishing a chronic reduction in kidney function and structural kidney damage, which presents with varied clinical manifestations. CKD may be associated with elevation of serum prolactin (PRL) levels. In addition to sexual dysfunction, PRL may have several biologic actions that participate in the atherosclerotic process and lead to insulin resistance. It may also be associated with endothelial dysfunction and lipid profile abnormalities. Objective The objective of this work was to evaluate serum PRL level in male patients with CKD. Patients and methods This study was conducted on 90 male participants, aged 30–60 years old. They were divided into two groups: group 1 comprised 60 male participants diagnosed with CKD, and group 2 included 30 age-matched healthy individuals as a control group. CKD group was subdivided into compensated CKD and CKD on hemodialysis. Results Among 60 patients with CKD, 48 (80%) patients had elevated serum PRL compared with normal serum PRL in group 2. A significant positive correlation was found between PRL and serum creatinine (r=0.259, P<0.05) and a negative correlation was observed between PRL and estimated glomerular filtration rate (r=−0.259, P>0.05). Patients with CKD on hemodialysis had higher PRL level compared with patients with compensated CKD (P<0.05). Conclusion CKD is associated with hyperprolactinemia which was found in most patients.
{"title":"Serum prolactin level in male patients with chronic kidney diseases","authors":"Sahar Gamman, Fatma Hammad, Waleed A. Taha, Osama Bakheet, I. Ahmad","doi":"10.4103/sjamf.sjamf_35_21","DOIUrl":"https://doi.org/10.4103/sjamf.sjamf_35_21","url":null,"abstract":"Background Chronic kidney disease (CKD) arises from many heterogeneous disease pathways that alter the function and structure of the kidney irreversibly, over months or years. The diagnosis of CKD rests on establishing a chronic reduction in kidney function and structural kidney damage, which presents with varied clinical manifestations. CKD may be associated with elevation of serum prolactin (PRL) levels. In addition to sexual dysfunction, PRL may have several biologic actions that participate in the atherosclerotic process and lead to insulin resistance. It may also be associated with endothelial dysfunction and lipid profile abnormalities. Objective The objective of this work was to evaluate serum PRL level in male patients with CKD. Patients and methods This study was conducted on 90 male participants, aged 30–60 years old. They were divided into two groups: group 1 comprised 60 male participants diagnosed with CKD, and group 2 included 30 age-matched healthy individuals as a control group. CKD group was subdivided into compensated CKD and CKD on hemodialysis. Results Among 60 patients with CKD, 48 (80%) patients had elevated serum PRL compared with normal serum PRL in group 2. A significant positive correlation was found between PRL and serum creatinine (r=0.259, P<0.05) and a negative correlation was observed between PRL and estimated glomerular filtration rate (r=−0.259, P>0.05). Patients with CKD on hemodialysis had higher PRL level compared with patients with compensated CKD (P<0.05). Conclusion CKD is associated with hyperprolactinemia which was found in most patients.","PeriodicalId":22975,"journal":{"name":"The Scientific Journal of Al-Azhar Medical Faculty, Girls","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77522712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.4103/sjamf.sjamf_38_21
Menna-Allah Mohamed, N. Ismail, Hesham Sami
Background The benign paroxysmal positional vertigo (BPPV) is a balance disorder with the most brilliant response to repositioning maneuvers; nevertheless, some patients report for a certain period afterward, imbalance without positional vertigo, named residual dizziness (RD). This imbalance is often described as a sensation of lightheadedness or dizziness in absence of vertigo or nystagmus, or short-lasting unsteadiness occurring during head movements, standing, or walking. Aim To evaluate the possible factors involved in RD after successful repositioning maneuvers for BPPV in the elderly. Patients and methods This study was done on 100 patients complaining of RD after successful repositioning maneuver; their ages were not less than 60 years old. The study was done during the period from November 2017 to march 2019 at the audiovestibular unit of ENT Department at Minia University Hospital and approved by the Ethics Committee, and all patients gave their informed consent before inclusion in the study. Data were collected on the characteristics and duration of any RD, and the clinical factors associated with the RD were analyzed using a specialized computer statistical program. Results The study showed that there were significant relationships between RD and other systemic diseases such as uncontrolled hypertension, uncontrolled diabetes, anxiety, depression, cataract, osteoporosis, tinnitus, vitamin D deficiency, joint pain, migraine, heart diseases, anemia, glaucoma, pneumonia, and polyneuropathy. Conclusion There is increased risk of RD after successful repositioning maneuvers in elderly patients with BPPV owing to many factors, and fast diagnosis is desirable to avoid risk of falls and anxiety related to unsteadiness in these patients.
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