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Trapped lung: a review of literature and recent cases 肺陷:文献及近期病例回顾
Pub Date : 2023-01-24 DOI: 10.12746/swrccc.v11i46.1121
D. Vangipuram
A trapped lung, one that cannot expand due to a restrictive fibrous visceral pleural peel, is caused by malignancy, chest trauma, thoracic surgery, complicated infection, and autoimmune conditions. Suspicion for and evaluation of this condition should be considered early on in a patient with history of the above conditions that presents with a chronic pleural effusion of stable volume. Diagnosis is reached with pleural fluid analysis, manometry that shows negative intrapleural pressure that is further reduced with fluid aspiration, and imaging that shows a chronic effusion and pleural thickening. Treatment is dependent on symptomatology and overall patient condition, and ranges from observation to fluid removal, fibrinolytic therapy, talc pleurodesis, indwelling pleural catheter, and surgical decortication. A review of English literature from the last 10 years including case reports, case series, and observational reviews was conducted. A majority of these patients presented with trapped lung due to malignancy, infection, or autoimmune conditions. Treatment varied depending on the cause of the trapped lung, underlying conditions, and patient preference; a majority of these patients received either pleurodesis, intrapleural fibrinolytic therapy, or surgical decortication.
由于限制性纤维性内脏胸膜剥离而不能扩张的肺被困,是由恶性肿瘤、胸部创伤、胸外科手术、复杂感染和自身免疫性疾病引起的。对于有上述病史的患者,当其表现为体积稳定的慢性胸腔积液时,应及早考虑对这种情况的怀疑和评估。通过胸膜液分析得出诊断,测压显示胸腔内压为负,吸液后进一步降低,影像学显示慢性积液和胸膜增厚。治疗取决于症状和患者的整体状况,包括观察、液体清除、纤溶治疗、滑石粉胸膜清释术、留置胸膜导管和手术脱屑。我们回顾了过去10年的英国文献,包括病例报告、病例系列和观察性综述。这些患者中的大多数由于恶性肿瘤、感染或自身免疫性疾病而出现肺陷。治疗方法因肺陷陷的原因、基础条件和患者偏好而异;这些患者中的大多数接受了胸膜切除术、胸膜内纤溶治疗或手术去皮术。
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引用次数: 0
Ivermectin - an antiviral drug for the COVID-19 pandemic? 伊维菌素——COVID-19大流行的抗病毒药物?
Pub Date : 2023-01-24 DOI: 10.12746/swrccc.v11i46.1141
C. Peterson, A. Ammu, Audrey Mangwiro, Christopher J. Crist
Abstract The use of ivermectin for the treatment of COVID-19 infections has been a subject of significant interest and controversy. The drug has a history of off-label use for a variety of clinical disorders and has shown some potential as an antiviral drug in in vitro studies and animal studies, and it has a relatively favorable safety profile. Multiple studies have been published examining the use of ivermectin against COVID-19. While several studies suggested it could be an effective therapeutic, most of these studies were insufficiently robust, had design flaws, or did not report any changes in important clinical outcomes, such as mortality. A smaller number of more robust studies did not support ivermectin use for COVID-19 treatment. Therefore, at present, ivermectin cannot be recommended for the treatment of COVID-19. While further studies may be warranted, this decision must be weighed against the possibility that this research may not alter current recommendations on the use of ivermectin in COVID-19 infections.    Keywords: COVID-19; ivermectin; prophylaxis, hospitalization, respiratory failure, mortality  
使用伊维菌素治疗COVID-19感染一直是一个备受关注和争议的话题。该药有标签外使用的历史,用于多种临床疾病,并在体外研究和动物研究中显示出作为抗病毒药物的一些潜力,并且具有相对有利的安全性。已经发表了多项研究,检查使用伊维菌素治疗COVID-19。虽然有几项研究表明它可能是一种有效的治疗方法,但这些研究大多不够可靠,存在设计缺陷,或者没有报告重要临床结果(如死亡率)的任何变化。少数更有力的研究不支持使用伊维菌素治疗COVID-19。因此,目前尚不能推荐使用伊维菌素治疗COVID-19。虽然可能需要进一步的研究,但必须权衡这一决定与这项研究可能不会改变目前关于在COVID-19感染中使用伊维菌素的建议的可能性。关键词:COVID-19;伊维菌素;预防,住院,呼吸衰竭,死亡
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引用次数: 1
Unusual cause of gastrointestinal bleeding in a patient with chronic pancreatitis 慢性胰腺炎患者消化道出血的不寻常原因
Pub Date : 2023-01-24 DOI: 10.12746/swrccc.v11i46.1123
Juthipong Benjanuwattra, N. Eshak, Mahmoud Abdelnabi
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引用次数: 0
COVID Policy: The Sorcerer’s Apprentice COVID政策:魔法师的学徒
Pub Date : 2023-01-24 DOI: 10.12746/swrccc.v11i46.1125
G. Berdine
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引用次数: 0
A rare case of Rhodococcus osteomyelitis 罕见的红球菌骨髓炎1例
Pub Date : 2023-01-24 DOI: 10.12746/swrccc.v11i46.1059
S. Tasnim, Dhara Dave, N. Dweik, Sinan Yaqoob, Naguib Tarek
Rhodococcus is a rare zoonotic infection causing cavitary pneumonia in immunocompromised humans. There had been very few reported incidences of Rhodococcus osteomyelitis. Our patient is a 27 years old male with human immunodeficiency virus (HIV) infection who was diagnosed with Rhodococcus osteomyelitis and bacteremia. He initially presented with right hip pain and was diagnosed with osteomyelitis and abscess based on a CT scan. IR guided drainage of the abscess was done and culture yielded R. equi. He failed antibiotic treatment multiple times and later was managed with surgical intervention. Although it is a rare case, physicians should keep it in mind especially in immunocompromised patients while deciding on diagnosis and treatment plans.
红球菌是一种罕见的人畜共患感染引起空洞性肺炎免疫功能低下的人。关于红球菌骨髓炎的报道很少。我们的病人是一名27岁男性,感染人类免疫缺陷病毒(HIV),被诊断为红球菌骨髓炎和菌血症。他最初表现为右髋关节疼痛,并根据CT扫描诊断为骨髓炎和脓肿。在红外引导下引流脓肿,培养出马脓杆菌。他多次抗生素治疗失败,后来进行了手术干预。虽然这是一种罕见的病例,但医生在决定诊断和治疗计划时应牢记这一点,特别是免疫功能低下的患者。
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引用次数: 0
Cases with uncharacteristic bacteria in canaliculitis 小管炎伴非特征性细菌病例
Pub Date : 2023-01-24 DOI: 10.12746/swrccc.v11i46.1113
Harrison Marsh, Addie Pederson, Coby Ray, K. Freedman
Canaliculitis is not considered to be a common condition and can be frequently misdiagnosed. The condition can also be challenging to eradicate. Canaliculitis accounts for 2-4% of lacrimal disease and is most often associated with Actinomyces israelii, Staphylococcus, and Strepococcus. However, these cases represent occasions of canaliculitis caused by uncharacteristic bacteria. We herein report three unique cases of canaliculitis that each required probing and irrigation of the infected lacrimal duct to culture bacteria following resistance to initial antibacterial treatment. Each case resulted in a different microbe, the cultures of the expelled purulent material grew Eikenella corrodens, Parvimonas micra, andCorynebacterium jeikeium respectively. All three cases occurred in rural west Texas woman with ages of 68, 70, and 40 years-old respectively. These cases highlight the importance of recognizing the possible involvement of uncharacteristic bacteria for the proper management of canaliculitis and proceeding to appropriate lacrimal procedures when empiric therapy is ineffective.
小管炎不被认为是一种常见的疾病,并且经常被误诊。这种情况也很难根除。小管炎占泪道疾病的2-4%,最常与以色列放线菌、葡萄球菌和链球菌有关。然而,这些病例是由非特征性细菌引起的小管炎。我们在此报告三个独特的小管炎病例,每个病例都需要探查和冲洗感染的泪管,以培养细菌,并对最初的抗菌治疗产生耐药性。每个病例都产生了不同的微生物,排出的化脓性物质培养出了腐蚀艾肯氏菌、微小细小单胞菌和耶氏棒状杆菌。这三例病例均发生在德克萨斯州西部农村,年龄分别为68岁、70岁和40岁。这些病例强调了识别可能涉及的非特征性细菌对于正确处理小管炎的重要性,并在经验治疗无效时进行适当的泪道手术。
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引用次数: 0
Relapsing polychondritis presenting as otitis externa 复发性多软骨炎表现为外耳炎
Pub Date : 2023-01-24 DOI: 10.12746/swrccc.v11i46.1087
Benjamin Lee, Christopher Peterson, Joshua Peterson, M. Lacy
Relapsing polychondritis remains a challenging diagnosis with cartilage inflammation being the hallmark disease pathology. Typical presentations include inflammation of auricular cartilage and joints, although multiple sites can be affected. Symptoms often overlap with other diseases and diagnosis is often delayed. Neurologic symptoms are rare and are attributed to CNS vasculitis. Here we report a rare case of relapsing polychondritis with neurological symptoms. This case illustrates both the challenges of diagnosis and the need to consider relapsing polychondritis in cases of cartilaginous inflammation.
复发性多软骨炎仍然是一个具有挑战性的诊断,软骨炎症是标志性的疾病病理学。典型的表现包括耳廓软骨和关节的炎症,尽管多个部位可能受到影响。症状往往与其他疾病重叠,诊断往往被推迟。神经系统症状是罕见的,并归因于中枢神经系统血管炎。我们在此报告一例罕见的复发性多软骨炎伴神经系统症状。这个病例说明了在软骨炎症的情况下,诊断的挑战和考虑复发多软骨炎的需要。
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引用次数: 0
Tic-“tack”-toe, out I go: A strategic implementation of flexible bronchoscopy in the removal of an aspirated thumbtack Tic-“图钉”-toe, out I go:灵活支气管镜在去除吸入性图钉中的策略实施
Pub Date : 2023-01-24 DOI: 10.12746/swrccc.v11i46.1083
S. Tasnim, B. Mohanakrishnan, Nandini Ray, Manish Patel
Thumbtack aspiration is a medical emergency as the sharp end poses a risk of injuring the respiratory tract and potentially causing fatal complications. Its removal can be difficult, even under bronchoscopy guidance, as the sharp end can potentially lead to bronchial mucosal tears and perforation. We present a case of a 16-year-old male who was admitted following the unintentional ingestion of a thumbtack which was removed via flexible bronchoscopy. These sharp metal objects are commonly removed using rigid bronchoscopy, but removal by flexible bronchoscopy, although challenging, is still possible.
图钉抽吸是一种医疗紧急情况,因为尖锐的末端有伤害呼吸道的危险,并可能导致致命的并发症。即使在支气管镜指导下,它的切除也很困难,因为尖锐的末端可能导致支气管粘膜撕裂和穿孔。我们提出的情况下,一个16岁的男性谁是入院后无意摄入的图钉是通过灵活的支气管镜切除。这些尖锐的金属物体通常使用刚性支气管镜去除,但通过柔性支气管镜去除,尽管具有挑战性,仍然是可能的。
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引用次数: 0
Comparisons between health care practices in Nazi Germany and the current United States 纳粹德国和当今美国医疗保健做法的比较
Pub Date : 2023-01-24 DOI: 10.12746/swrccc.v11i46.1135
G. Berdine
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引用次数: 0
Carotid cavernous fistula presenting as orbital cellulitis 颈动脉海绵窦瘘表现为眶蜂窝织炎
Pub Date : 2023-01-08 DOI: 10.12746/swrccc.v11i46.1091
Christopher Peterson, Benjamin Lee, Mark Lacy
Carotid cavernous fistula is a serious vascular pathology that is commonly misdiagnosed due to clinical signs that overlap with several other pathologies and the need for sensitive imaging techniques, most notably digital subtraction angiography, to make the diagnosis. Here we present a case of carotid cavernous fistula mimicking orbital cellulitis, ultimately diagnosed with magnetic resonance venography.
颈动脉海绵状瘘是一种严重的血管病理,由于临床症状与其他几种病理重叠,并且需要敏感的成像技术,尤其是数字减影血管造影来诊断,因此经常被误诊。我们在此报告一个颈动脉海绵窦瘘模拟眼眶蜂窝织炎的病例,最终通过磁共振静脉造影诊断。
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The Southwest Respiratory and Critical Care Chronicles
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