Pub Date : 2024-11-05eCollection Date: 2024-01-01DOI: 10.1155/2024/9423417
Boikanyo Makubate
The Odd Weibull-G (OWG) family of distributions has been discussed earlier in the literature. This family of distributions provides a "better fit" in certain practical situations. In a similar fashion, the OWG family of distributions is defined in this article. A method of moments estimator based on the maximum entropy principle is proposed for the discrimination of two members of the OWG family of distributions.
{"title":"A Test for Discriminating Between Members of the Odd Weibull-G Family of Distributions.","authors":"Boikanyo Makubate","doi":"10.1155/2024/9423417","DOIUrl":"https://doi.org/10.1155/2024/9423417","url":null,"abstract":"<p><p>The Odd Weibull-G (OWG) family of distributions has been discussed earlier in the literature. This family of distributions provides a \"better fit\" in certain practical situations. In a similar fashion, the OWG family of distributions is defined in this article. A method of moments estimator based on the maximum entropy principle is proposed for the discrimination of two members of the OWG family of distributions.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"9423417"},"PeriodicalIF":0.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-04eCollection Date: 2024-01-01DOI: 10.1155/2024/8899070
Lyndon N A Sackey, Rita Kwablah, Lawrencia S Y Agyemang
Water is crucial for life, and although groundwater is considered safe, it can degrade due to inadequate source protection and inefficient resource management. The aim of the study was to assess the impact of landfill operations on water quality from selected landfill sites. Spectrometry analytical techniques were used to assess the physicochemical parameters of the samples. The study found that while Salmonella was absent in most samples, E. coli and total coliforms were present, making the water unsafe for domestic use. Although turbidity, pH, temperature and other parameters were within acceptable GSA/WHO levels, total coliform and E. coli raise concerns about faecal contamination and potential health risks. Cadmium was absent in all samples, but chromium, lead, arsenic and mercury were detected. These heavy metals could pose health hazards to consumers. The samples showed no risk of noncarcinogenic and carcinogenic risk to consumers, but then there is a potential health risk to consumers over time due to bioaccumulation. Regular monitoring and periodic assessments are recommended to ensure water safety. Proper waste management practices in landfill areas can minimize potential impacts on water quality, highlighting the need for continuous monitoring and assessment. The municipal authorities can inform residents of the situation and put in policies to protect human health. The results could help residents know the level of contamination of water from their boreholes and the necessary precautions to take to reduce their health impact. A treatment system can be developed in detail to their peculiar need.
{"title":"The Impact of Landfill Operations on Borehole Water Quality.","authors":"Lyndon N A Sackey, Rita Kwablah, Lawrencia S Y Agyemang","doi":"10.1155/2024/8899070","DOIUrl":"https://doi.org/10.1155/2024/8899070","url":null,"abstract":"<p><p>Water is crucial for life, and although groundwater is considered safe, it can degrade due to inadequate source protection and inefficient resource management. The aim of the study was to assess the impact of landfill operations on water quality from selected landfill sites. Spectrometry analytical techniques were used to assess the physicochemical parameters of the samples. The study found that while Salmonella was absent in most samples, <i>E. coli</i> and total coliforms were present, making the water unsafe for domestic use. Although turbidity, pH, temperature and other parameters were within acceptable GSA/WHO levels, total coliform and <i>E. coli</i> raise concerns about faecal contamination and potential health risks. Cadmium was absent in all samples, but chromium, lead, arsenic and mercury were detected. These heavy metals could pose health hazards to consumers. The samples showed no risk of noncarcinogenic and carcinogenic risk to consumers, but then there is a potential health risk to consumers over time due to bioaccumulation. Regular monitoring and periodic assessments are recommended to ensure water safety. Proper waste management practices in landfill areas can minimize potential impacts on water quality, highlighting the need for continuous monitoring and assessment. The municipal authorities can inform residents of the situation and put in policies to protect human health. The results could help residents know the level of contamination of water from their boreholes and the necessary precautions to take to reduce their health impact. A treatment system can be developed in detail to their peculiar need.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"8899070"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-28eCollection Date: 2024-01-01DOI: 10.1155/2024/5538398
Lyndon N A Sackey, Augustine Okobeng, Priscilla Yawa Obidieh, Flora-Marie Mpaka Ngala, Emmanuel Bentum Otoo, Jeremiah Quartey, Joseph A Bentil, David Azanu
The disposal of pharmaceutical wastewater has gained increasing attention due to its potential adverse effects on the environment and public health. This study aims to assess the concentration of pharmaceutical contaminants and their toxicity to aquatic organisms. A qualitative research approach was used. Composite samples were collected from the effluent storage system. Various analytical techniques, including high-performance liquid chromatography (HPLC), were employed to detect and quantify pharmaceutical compounds in wastewater samples. The results revealed various pharmaceutical compounds (ibuprofen 28 μg/L, diclofenac 27.20 μg/L, paracetamol 22.03 μg/L, and tramadol <0.01 μg/L) in the wastewater. The maximal environmental concentration (MEC) for all the detected pharmaceuticals was high; hence, the risk quotients (RQs) indicated potential toxicity (RO > 1). It further indicates that the effluent was more toxic to animals (daphnia and fish) than algae (plants). It can be concluded that pharmaceutical effluent was toxic to aquatic organisms. Therefore, there is a need to implement stringent regulatory measures to mitigate untreated pharmaceutical effluent in water bodies. Addressing pharmaceutical contaminants in wastewater is crucial to safeguarding the environment and public health in an increasing pharmaceutical use and production era.
{"title":"Risk Assessment of Pharmaceutical Contaminants in Pharmaceutical Wastewater.","authors":"Lyndon N A Sackey, Augustine Okobeng, Priscilla Yawa Obidieh, Flora-Marie Mpaka Ngala, Emmanuel Bentum Otoo, Jeremiah Quartey, Joseph A Bentil, David Azanu","doi":"10.1155/2024/5538398","DOIUrl":"10.1155/2024/5538398","url":null,"abstract":"<p><p>The disposal of pharmaceutical wastewater has gained increasing attention due to its potential adverse effects on the environment and public health. This study aims to assess the concentration of pharmaceutical contaminants and their toxicity to aquatic organisms. A qualitative research approach was used. Composite samples were collected from the effluent storage system. Various analytical techniques, including high-performance liquid chromatography (HPLC), were employed to detect and quantify pharmaceutical compounds in wastewater samples. The results revealed various pharmaceutical compounds (ibuprofen 28 <i>μ</i>g/L, diclofenac 27.20 <i>μ</i>g/L, paracetamol 22.03 <i>μ</i>g/L, and tramadol <0.01 <i>μ</i>g/L) in the wastewater. The maximal environmental concentration (MEC) for all the detected pharmaceuticals was high; hence, the risk quotients (RQs) indicated potential toxicity (RO > 1). It further indicates that the effluent was more toxic to animals (daphnia and fish) than algae (plants). It can be concluded that pharmaceutical effluent was toxic to aquatic organisms. Therefore, there is a need to implement stringent regulatory measures to mitigate untreated pharmaceutical effluent in water bodies. Addressing pharmaceutical contaminants in wastewater is crucial to safeguarding the environment and public health in an increasing pharmaceutical use and production era.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"5538398"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11535420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-28eCollection Date: 2024-01-01DOI: 10.1155/2024/4943983
Chowda Reddy C, K M Kenchi Reddy, C T Jayadeva, Ramesh Kumar S C, R Vara Prasad Kaviti, Abhijit Bhowmik, Chander Prakash
This research paper investigates the effectiveness of shielded metal arc welding (SMAW) and flux-cored arc welding (FCAW) on mild steel substrates for chromium-boron hardfacing. Chromium-boron alloys are hard-wearing and corrosion-resistant materials used in industries where wear resistance is critical. The study aims to identify the best welding technique for increasing surface hardness and wear resistance. Standard test specimens were chosen and deposited using SMAW and FCAW processes. SMAW uses an electrode covered with flux, which turns into a sticky state when heated, while FCAW uses a core wire fabricated from flux, which generates a shielded gas upon melting. The effectiveness of each welding technique is assessed based on deposition efficiency, dilution rate, microstructure, hardness distribution, and wear resistance. This research helps industries choose the most efficient material and method for improving wear and corrosion resistance in applications like mining, construction, agriculture, and manufacturing. On average, FCAW offers a 1.67% improvement in hardness and 28.12% improvement in mass loss reduction when compared to SMAW.
{"title":"A Comparative Assessment of Chromium-Boron Hardfacing Using SMAW and FCAW Techniques.","authors":"Chowda Reddy C, K M Kenchi Reddy, C T Jayadeva, Ramesh Kumar S C, R Vara Prasad Kaviti, Abhijit Bhowmik, Chander Prakash","doi":"10.1155/2024/4943983","DOIUrl":"https://doi.org/10.1155/2024/4943983","url":null,"abstract":"<p><p>This research paper investigates the effectiveness of shielded metal arc welding (SMAW) and flux-cored arc welding (FCAW) on mild steel substrates for chromium-boron hardfacing. Chromium-boron alloys are hard-wearing and corrosion-resistant materials used in industries where wear resistance is critical. The study aims to identify the best welding technique for increasing surface hardness and wear resistance. Standard test specimens were chosen and deposited using SMAW and FCAW processes. SMAW uses an electrode covered with flux, which turns into a sticky state when heated, while FCAW uses a core wire fabricated from flux, which generates a shielded gas upon melting. The effectiveness of each welding technique is assessed based on deposition efficiency, dilution rate, microstructure, hardness distribution, and wear resistance. This research helps industries choose the most efficient material and method for improving wear and corrosion resistance in applications like mining, construction, agriculture, and manufacturing. On average, FCAW offers a 1.67% improvement in hardness and 28.12% improvement in mass loss reduction when compared to SMAW.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"4943983"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11535419/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: One of the most important causes of cardiovascular disease is hypertension. Lifestyle modification has been emphasized in preventing and controlling blood pressure. This research aimed to determine the effect of educational intervention by application of PRECEDE-PROCEED model on lifestyle change in hypertensive patients in the villages of Fasa City, Fars Province, Iran. Methods: This research is a quasi-experimental study that was conducted on 300 hypertensive patients in 2020-2021. Data gathering tools were a demographic information questionnaire, a questionnaire based on the PRECEDE-PROCEED model, and a lifestyle questionnaire (LSQ). The educational intervention consisted of ten sessions lasting 45 or 50 min. Before and 6 months after the educational intervention, the two groups each completed a questionnaire. The systolic and diastolic blood pressure (DBP) levels, as well as physical exercise and health variables, nutrition and weight control, mental health, and spiritual health were measured before and 6 months after the educational intervention. Results: The results showed that there was no significant difference between the two groups before in cues of PRECEDE-PROCEED model; however, the experimental group had a significant increase in cues of PRECEDE-PROCEED model 6 months after the intervention. The results showed that the experimental group had a significant increase 6 months after the intervention in terms of physical exercise and health variables, nutrition and weight control, mental health, and spiritual health. The mean blood pressure (both diastolic and systolic) in the experimental group was significantly reduced after the intervention. Conclusions: The study's results showed the effectiveness of an educational intervention based on the PRECEDE-PROCEED model on lifestyle change in hypertensive patients. It also highlights the need to pay further attention to the education aimed at controlling hypertension through a healthy lifestyle and correct behavioral habits.
{"title":"Effect of Educational Intervention by Application of PRECEDE-PROCEED Model on Lifestyle Change in Hypertensive Patients.","authors":"Alireza Ghannadi, Fatemeh Mohammadkhah, Pooyan Afzali Harsini, Afsaneh Ghasemi, Amirhossein Kamyab, Ali Khani Jeihooni","doi":"10.1155/2024/5523473","DOIUrl":"10.1155/2024/5523473","url":null,"abstract":"<p><p><b>Background:</b> One of the most important causes of cardiovascular disease is hypertension. Lifestyle modification has been emphasized in preventing and controlling blood pressure. This research aimed to determine the effect of educational intervention by application of PRECEDE-PROCEED model on lifestyle change in hypertensive patients in the villages of Fasa City, Fars Province, Iran. <b>Methods:</b> This research is a quasi-experimental study that was conducted on 300 hypertensive patients in 2020-2021. Data gathering tools were a demographic information questionnaire, a questionnaire based on the PRECEDE-PROCEED model, and a lifestyle questionnaire (LSQ). The educational intervention consisted of ten sessions lasting 45 or 50 min. Before and 6 months after the educational intervention, the two groups each completed a questionnaire. The systolic and diastolic blood pressure (DBP) levels, as well as physical exercise and health variables, nutrition and weight control, mental health, and spiritual health were measured before and 6 months after the educational intervention. <b>Results:</b> The results showed that there was no significant difference between the two groups before in cues of PRECEDE-PROCEED model; however, the experimental group had a significant increase in cues of PRECEDE-PROCEED model 6 months after the intervention. The results showed that the experimental group had a significant increase 6 months after the intervention in terms of physical exercise and health variables, nutrition and weight control, mental health, and spiritual health. The mean blood pressure (both diastolic and systolic) in the experimental group was significantly reduced after the intervention. <b>Conclusions:</b> The study's results showed the effectiveness of an educational intervention based on the PRECEDE-PROCEED model on lifestyle change in hypertensive patients. It also highlights the need to pay further attention to the education aimed at controlling hypertension through a healthy lifestyle and correct behavioral habits.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"5523473"},"PeriodicalIF":0.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11527526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-24eCollection Date: 2024-01-01DOI: 10.1155/2024/3168279
Isaac Osei-Safo, Kodwo Miezah, Lyndon Nii Adjiri Sackey, Junias Adusei-Gyamfi, Ayamba Malik Abdul
Spices enhance food's colour, aroma and palatability. The main objective of this study was to assess the levels of heavy metals in the most common spices used in Ghanaian and worldwide cuisines. Ninety samples were obtained directly from local marketplaces in the Accra Metropolis (Madina, Kaneshie and Makola). After microwave digestion, the samples' levels of arsenic, iron, lead, cadmium and zinc were measured using an inductively coupled plasma-mass spectrometer (ICP-MS). Iron, zinc, arsenic, cadmium and lead levels in specified natural spices varied from 0.022 mg/kg to 5.814 mg/kg, 0.056 mg/kg to 0.895 mg/kg, not detected to 14.012 mg/kg, 0.02 mg/kg to 0.45 mg/kg and not detected to 3.583 mg/kg, respectively. The toxic metals arsenic and lead in turmeric powder, whole rosemary and garlic, as well as lead in ginger, were slightly above the Codex, but below the FAO/WHO permissible level. All spices in this study had THQ and HI values of less than one, indicating that consumers will experience no potential health hazards from consuming specific metals through spices. However, continual scrutiny should be maintained over time due to bioaccumulation in humans.
{"title":"Trace and Heavy Metals in Locally and Imported Spices Sold on Markets in Accra Metropolis, Ghana.","authors":"Isaac Osei-Safo, Kodwo Miezah, Lyndon Nii Adjiri Sackey, Junias Adusei-Gyamfi, Ayamba Malik Abdul","doi":"10.1155/2024/3168279","DOIUrl":"10.1155/2024/3168279","url":null,"abstract":"<p><p>Spices enhance food's colour, aroma and palatability. The main objective of this study was to assess the levels of heavy metals in the most common spices used in Ghanaian and worldwide cuisines. Ninety samples were obtained directly from local marketplaces in the Accra Metropolis (Madina, Kaneshie and Makola). After microwave digestion, the samples' levels of arsenic, iron, lead, cadmium and zinc were measured using an inductively coupled plasma-mass spectrometer (ICP-MS). Iron, zinc, arsenic, cadmium and lead levels in specified natural spices varied from 0.022 mg/kg to 5.814 mg/kg, 0.056 mg/kg to 0.895 mg/kg, not detected to 14.012 mg/kg, 0.02 mg/kg to 0.45 mg/kg and not detected to 3.583 mg/kg, respectively. The toxic metals arsenic and lead in turmeric powder, whole rosemary and garlic, as well as lead in ginger, were slightly above the Codex, but below the FAO/WHO permissible level. All spices in this study had THQ and HI values of less than one, indicating that consumers will experience no potential health hazards from consuming specific metals through spices. However, continual scrutiny should be maintained over time due to bioaccumulation in humans.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"3168279"},"PeriodicalIF":0.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11527527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ocimum tenuiflorum, commonly known as Tulsi, is revered in Ayurveda for its extensive medicinal properties. However, there is a need to consolidate current knowledge on its phytochemical constituents and their pharmacological activities to identify potential areas for further research and drug development. This review aims to bridge this gap by providing a comprehensive analysis of the bioactive secondary metabolites found in O. tenuiflorum, such as rosmarinic acid, oleanolic acid, luteolin, ursolic acid, and limonene, and their associated therapeutic effects. The review will highlight the pharmacological importance of these metabolites, which exhibit antioxidant, neuroprotective, anticancer, and anti-inflammatory properties. Additionally, this study will explore the plant's wide range of beneficial qualities, including anti-inflammatory, antioxidant, anticholinergic, pain-relieving, antimicrobial, stress-reducing, antidiabetic, anticancer, liver-protective, ulcer-inhibiting, antifungal, and wound-healing attributes. Furthermore, this review focuses on the plant's potential in treating conditions such as asthma, persistent fever, tuberculosis, malaria, skin discoloration, itching, digestive issues, hemorrhoids, bone fractures, gout, urinary tract infection, and diabetes. By reviewing the current literature, the aim is to identify the gaps in the existing research and propose directions for future studies. This comprehensive review will serve as a valuable resource for researchers in the development and investigation of novel drugs derived from O. tenuiflorum.
Ocimum tenuiflorum(俗称 Tulsi)因其广泛的药用特性而在阿育吠陀中备受推崇。然而,有必要整合有关其植物化学成分及其药理活性的现有知识,以确定进一步研究和药物开发的潜在领域。本综述旨在弥合这一差距,全面分析在天南星(O. tenuiflorum)中发现的具有生物活性的次生代谢物,如迷迭香酸、齐墩果酸、木犀草素、熊果酸和柠檬烯,以及它们的相关治疗效果。综述将强调这些代谢物的药理重要性,它们具有抗氧化、神经保护、抗癌和抗炎特性。此外,本研究还将探讨该植物的多种有益特性,包括抗炎、抗氧化、抗胆碱能、止痛、抗菌、减轻压力、抗糖尿病、抗癌、保肝、抑制溃疡、抗真菌和伤口愈合特性。此外,本综述还重点介绍了该植物在治疗哮喘、持续发烧、肺结核、疟疾、皮肤变色、瘙痒、消化问题、痔疮、骨折、痛风、尿路感染和糖尿病等疾病方面的潜力。通过回顾现有文献,旨在找出现有研究中的不足,并提出未来研究的方向。这篇全面的综述将成为研究人员开发和研究从 O. tenuiflorum 提取的新型药物的宝贵资源。
{"title":"A Comprehensive Review of the Phytochemical Constituents and Bioactivities of <i>Ocimum tenuiflorum</i>.","authors":"Keshab Bhattarai, Rabin Bhattarai, Ram Darash Pandey, Babita Paudel, Hari Datta Bhattarai","doi":"10.1155/2024/8895039","DOIUrl":"https://doi.org/10.1155/2024/8895039","url":null,"abstract":"<p><p><i>Ocimum tenuiflorum</i>, commonly known as Tulsi, is revered in Ayurveda for its extensive medicinal properties. However, there is a need to consolidate current knowledge on its phytochemical constituents and their pharmacological activities to identify potential areas for further research and drug development. This review aims to bridge this gap by providing a comprehensive analysis of the bioactive secondary metabolites found in <i>O. tenuiflorum</i>, such as rosmarinic acid, oleanolic acid, luteolin, ursolic acid, and limonene, and their associated therapeutic effects. The review will highlight the pharmacological importance of these metabolites, which exhibit antioxidant, neuroprotective, anticancer, and anti-inflammatory properties. Additionally, this study will explore the plant's wide range of beneficial qualities, including anti-inflammatory, antioxidant, anticholinergic, pain-relieving, antimicrobial, stress-reducing, antidiabetic, anticancer, liver-protective, ulcer-inhibiting, antifungal, and wound-healing attributes. Furthermore, this review focuses on the plant's potential in treating conditions such as asthma, persistent fever, tuberculosis, malaria, skin discoloration, itching, digestive issues, hemorrhoids, bone fractures, gout, urinary tract infection, and diabetes. By reviewing the current literature, the aim is to identify the gaps in the existing research and propose directions for future studies. This comprehensive review will serve as a valuable resource for researchers in the development and investigation of novel drugs derived from <i>O. tenuiflorum</i>.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"8895039"},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-12eCollection Date: 2024-01-01DOI: 10.1155/2024/1059164
Borut Kirn
A computational model enables the extraction of two critical myocardial tissue properties: activation time (AT) and contractility (Con) from recorded cardiac strains. However, interference between these parameters reduces the precision and accuracy of the extraction process. This study investigates whether leveraging features in the parameter space can enhance parameter extraction. We utilized a computational model to simulate sarcomere mechanics, creating a parameter space grid of 41 × 41 AT and Con pairs. Each pair generated a simulated strain pattern, and by scanning the grid, we identified cohorts of similar strain patterns for each simulation. These cohorts were represented as binary images-synthetic fingerprints-where the position and shape of each blob indicated extraction uniqueness. We also generated a measurement fingerprint for a strain pattern from a patient with left bundle branch block and compared it to the synthetic fingerprints to calculate a proximity map based on their similarity. This approach allowed us to extract AT and Con using both the measurement fingerprint and the proximity map, corresponding to simple optimization and enhanced parameter extraction methods, respectively. Each synthetic fingerprint consisted of a single connected blob whose size and shape varied characteristically within the parameter space. The AT values extracted from the measurement fingerprint and the proximity map ranged from -59 to 19 ms and from -16 to 14 ms, respectively, while Con values ranged from 48% to 110% and from 85% to 110%, respectively. This study demonstrates that similarity in simulations leads to an asymmetric distribution of parameter values in the parameter space. By using a proximity map, this distortion is considered, significantly improving the accuracy of parameter extraction.
计算模型可从记录的心脏应变中提取两个关键的心肌组织属性:活化时间(AT)和收缩力(Con)。然而,这些参数之间的干扰降低了提取过程的精度和准确性。本研究探讨了利用参数空间中的特征是否能增强参数提取。我们利用计算模型模拟肌节力学,创建了一个由 41 × 41 AT 和 Con 对组成的参数空间网格。每一对都会产生一个模拟应变模式,通过扫描网格,我们确定了每次模拟中相似应变模式的队列。这些群组被表示为二进制图像--合成指纹,其中每个圆球的位置和形状表示提取的唯一性。我们还为左束支传导阻滞患者的应变模式生成了测量指纹,并将其与合成指纹进行比较,根据它们的相似性计算出邻近图。通过这种方法,我们可以使用测量指纹和邻近图提取 AT 和 Con,分别对应于简单优化和增强参数提取方法。每个合成指纹都由单个相连的圆球组成,其大小和形状在参数空间内各不相同。从测量指纹和邻近图中提取的 AT 值范围分别为 -59 至 19 毫秒和 -16 至 14 毫秒,而 Con 值范围分别为 48% 至 110% 和 85% 至 110%。这项研究表明,模拟的相似性会导致参数空间中参数值的非对称分布。通过使用近似图,这种失真得到了考虑,从而大大提高了参数提取的准确性。
{"title":"Enhanced Extraction of Activation Time and Contractility From Myocardial Strain Data Using Parameter Space Features and Computational Simulations.","authors":"Borut Kirn","doi":"10.1155/2024/1059164","DOIUrl":"10.1155/2024/1059164","url":null,"abstract":"<p><p>A computational model enables the extraction of two critical myocardial tissue properties: activation time (AT) and contractility (Con) from recorded cardiac strains. However, interference between these parameters reduces the precision and accuracy of the extraction process. This study investigates whether leveraging features in the parameter space can enhance parameter extraction. We utilized a computational model to simulate sarcomere mechanics, creating a parameter space grid of 41 × 41 AT and Con pairs. Each pair generated a simulated strain pattern, and by scanning the grid, we identified cohorts of similar strain patterns for each simulation. These cohorts were represented as binary images-synthetic fingerprints-where the position and shape of each blob indicated extraction uniqueness. We also generated a measurement fingerprint for a strain pattern from a patient with left bundle branch block and compared it to the synthetic fingerprints to calculate a proximity map based on their similarity. This approach allowed us to extract AT and Con using both the measurement fingerprint and the proximity map, corresponding to simple optimization and enhanced parameter extraction methods, respectively. Each synthetic fingerprint consisted of a single connected blob whose size and shape varied characteristically within the parameter space. The AT values extracted from the measurement fingerprint and the proximity map ranged from -59 to 19 ms and from -16 to 14 ms, respectively, while Con values ranged from 48% to 110% and from 85% to 110%, respectively. This study demonstrates that similarity in simulations leads to an asymmetric distribution of parameter values in the parameter space. By using a proximity map, this distortion is considered, significantly improving the accuracy of parameter extraction.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"1059164"},"PeriodicalIF":0.0,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11490350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-12eCollection Date: 2024-01-01DOI: 10.1155/2024/9198533
Hinémé Fanday, Tchobsala
This study was conducted in the Mandara Mountains in Cameroon and aimed to assess the effects of human activities on woody vegetation in gallery forests, based on floristic inventories and observations made by the government. Firstly, the inventories were carried out in 150 plots of 1000 m2 each, installed on the banks of watercourses following the band of plant formations. In each plot, woody species were counted and those showing at least one sign of degradation were noted. Secondly, the survey was conducted in 18 administrative structures made up of delegations (MINFOF, MINADER, MINEPDED, and MINEPIA) and town halls. One hundred woody species, grouped into 63 genera and 30 families, have been inventoried, in which 45 species showed at least one sign of damage caused by human being. The species most affected are Anogeissus leiocarpus (67 stems), Azadirachta indica (46 stems), Diospyros mespiliformis (43 stems), Acacia albida (42 stems), Andira inermis (30 stems), Acacia sieberiana (23 stems), Khaya senegalensis (19 stems), Ficus sycomorus (13 stems), and Acacia polyacantha (10 stems). The most recurrent activity in the gallery forests is pruning (212 stems), followed by cutting (93 stumps), then picking (71 individuals). However, there are fewer debarked trees (11) and trees with fire trail (6). According to the responses provided, logging (77.78%), agriculture (72.22%), population growth (44.44%), grazing (33.33%), and bush fires (33.33%) are the main causes of the degradation of plant formations in the Mandara Mountains. These main factors could have a negative impact on biodiversity if appropriate integrated management measures are not taken. To maintain these vital ecosystems, an integrated management plan must be put in place, limiting human activities to a minimum.
{"title":"Impact of Human Activities on Woody Vegetation in Gallery Forests in the Mandara Mountains (Far North, Cameroon).","authors":"Hinémé Fanday, Tchobsala","doi":"10.1155/2024/9198533","DOIUrl":"https://doi.org/10.1155/2024/9198533","url":null,"abstract":"<p><p>This study was conducted in the Mandara Mountains in Cameroon and aimed to assess the effects of human activities on woody vegetation in gallery forests, based on floristic inventories and observations made by the government. Firstly, the inventories were carried out in 150 plots of 1000 m<sup>2</sup> each, installed on the banks of watercourses following the band of plant formations. In each plot, woody species were counted and those showing at least one sign of degradation were noted. Secondly, the survey was conducted in 18 administrative structures made up of delegations (MINFOF, MINADER, MINEPDED, and MINEPIA) and town halls. One hundred woody species, grouped into 63 genera and 30 families, have been inventoried, in which 45 species showed at least one sign of damage caused by human being. The species most affected are <i>Anogeissus leiocarpus</i> (67 stems), <i>Azadirachta indica</i> (46 stems), <i>Diospyros mespiliformis</i> (43 stems), <i>Acacia albida</i> (42 stems), <i>Andira inermis</i> (30 stems), <i>Acacia sieberiana</i> (23 stems), <i>Khaya senegalensis</i> (19 stems), <i>Ficus sycomorus</i> (13 stems), and <i>Acacia polyacantha</i> (10 stems). The most recurrent activity in the gallery forests is pruning (212 stems), followed by cutting (93 stumps), then picking (71 individuals). However, there are fewer debarked trees (11) and trees with fire trail (6). According to the responses provided, logging (77.78%), agriculture (72.22%), population growth (44.44%), grazing (33.33%), and bush fires (33.33%) are the main causes of the degradation of plant formations in the Mandara Mountains. These main factors could have a negative impact on biodiversity if appropriate integrated management measures are not taken. To maintain these vital ecosystems, an integrated management plan must be put in place, limiting human activities to a minimum.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"9198533"},"PeriodicalIF":0.0,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-09eCollection Date: 2024-01-01DOI: 10.1155/2024/2126734
Sewnet Getahun, Habtamu Kefale, Yohannes Gelaye
Precision agriculture technologies (PATs) transform crop production by enabling more sustainable and efficient agricultural practices. These technologies utilize data-driven approaches to optimize the management of crops, soil, and resources, thus enhancing both productivity and environmental sustainability. This article reviewed the application of PATs for sustainable crop production and environmental sustainability around the globe. Key components of PAT include remote sensing, GPS-guided equipment, variable rate technology (VRT), and Internet of Things (IoT) devices. Remote sensing and drones deliver high-resolution imagery and data, enabling precise monitoring of crop health, soil conditions, and pest activity. GPS-guided machinery ensures accurate planting, fertilizing, and harvesting, which reduces waste and enhances efficiency. VRT optimizes resource use by allowing farmers to apply inputs such as water, fertilizers, and pesticides at varying rates across a field based on real-time data and specific crop requirements. This reduces over-application and minimizes environmental impact, such as nutrient runoff and greenhouse gas emissions. IoT devices and sensors provide continuous monitoring of environmental conditions and crop status, enabling timely and informed decision-making. The application of PAT contributes significantly to environmental sustainability by promoting practices that conserve water, reduce chemical usage, and enhance soil health. By enhancing the precision of agricultural operations, these technologies reduce the environmental impact of farming, while simultaneously boosting crop yields and profitability. As the global demand for food increases, precision agriculture offers a promising pathway to achieving sustainable crop production and ensuring long-term environmental health.
{"title":"Application of Precision Agriculture Technologies for Sustainable Crop Production and Environmental Sustainability: A Systematic Review.","authors":"Sewnet Getahun, Habtamu Kefale, Yohannes Gelaye","doi":"10.1155/2024/2126734","DOIUrl":"10.1155/2024/2126734","url":null,"abstract":"<p><p>Precision agriculture technologies (PATs) transform crop production by enabling more sustainable and efficient agricultural practices. These technologies utilize data-driven approaches to optimize the management of crops, soil, and resources, thus enhancing both productivity and environmental sustainability. This article reviewed the application of PATs for sustainable crop production and environmental sustainability around the globe. Key components of PAT include remote sensing, GPS-guided equipment, variable rate technology (VRT), and Internet of Things (IoT) devices. Remote sensing and drones deliver high-resolution imagery and data, enabling precise monitoring of crop health, soil conditions, and pest activity. GPS-guided machinery ensures accurate planting, fertilizing, and harvesting, which reduces waste and enhances efficiency. VRT optimizes resource use by allowing farmers to apply inputs such as water, fertilizers, and pesticides at varying rates across a field based on real-time data and specific crop requirements. This reduces over-application and minimizes environmental impact, such as nutrient runoff and greenhouse gas emissions. IoT devices and sensors provide continuous monitoring of environmental conditions and crop status, enabling timely and informed decision-making. The application of PAT contributes significantly to environmental sustainability by promoting practices that conserve water, reduce chemical usage, and enhance soil health. By enhancing the precision of agricultural operations, these technologies reduce the environmental impact of farming, while simultaneously boosting crop yields and profitability. As the global demand for food increases, precision agriculture offers a promising pathway to achieving sustainable crop production and ensuring long-term environmental health.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2024 ","pages":"2126734"},"PeriodicalIF":0.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11483651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}