Pub Date : 2020-08-31DOI: 10.17945/kjbt.2020.31.2.119
Mi Nam Lee, K. Kim, Byoung-Gwon Kim, Ri-Young Goh, Jun Nyun Kim
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. CopyrightC2020 The Korean Society of Blood Transfusion 한국 공공 제대혈은행의 보관 정책 개선: 장기 보관 및 단기 보관 제대혈의 품질 비교
this is an open access article distributed under the terms of the creative creativecommons attribution non - commercial license (http: / /听说过。org / licenses / by - nc / 4.0) which permits unrestrictednon-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited。CopyrightC2020 The Korean Society of Blood Transfusion改善韩国公共脐带血银行的保管政策:长期保管及短期保管脐带血质量的比较
{"title":"Improving Storage Policy in Korean Public Cord Blood Banks: Comparison of Quality between Long-Term and Short-Term Storage of Cord Blood","authors":"Mi Nam Lee, K. Kim, Byoung-Gwon Kim, Ri-Young Goh, Jun Nyun Kim","doi":"10.17945/kjbt.2020.31.2.119","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.119","url":null,"abstract":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. CopyrightC2020 The Korean Society of Blood Transfusion 한국 공공 제대혈은행의 보관 정책 개선: 장기 보관 및 단기 보관 제대혈의 품질 비교","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121947393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-31DOI: 10.17945/kjbt.2020.31.2.101
Dae-Sang Lee
A massive blood transfusion is a challenging situation that can be encountered in the treatment of trauma patients. Under these circumstances, clinicians should conduct appropriate blood transfusions using the massive transfusion protocol, and make efforts to prepare and apply these protocols to the systems of each hospital in advance. In addition, the effect of massive bleeding on the body highlights the need to understand why fresh frozen plasma and platelets, as well as packed red blood cells (pRBC), are needed during massive transfusion. In hemorrhagic patients, blood pressure maintenance through transfusion is an important part, but above all, efforts to control sustained bleeding by controlling and treating the bleeding itself are more important. This is because patients need to recover their organs after early resuscitation by minimizing the side effects of transfusion. No research has been done to compare the restrictive transfusion and liberal transfusion strategies in patients requiring massive transfusion. On the other hand, various studies suggest that it is more advantageous to apply a liberal blood transfusion strategy in patients with severe or older age. Nevertheless, there has been insufficient research to apply it generally. Therefore, for patients whose resuscitation has been performed by applying a massive transfusion protocol, a reasonable treatment approach would be to shift to a strategy to supplement poor coagulation factors through a goal-directed transfusion. (Korean J Blood Transfus 2020;31:101-108)
{"title":"A Simple Comment of Trauma-Induced Coagulopathy and Massive Transfusion","authors":"Dae-Sang Lee","doi":"10.17945/kjbt.2020.31.2.101","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.101","url":null,"abstract":"A massive blood transfusion is a challenging situation that can be encountered in the treatment of trauma patients. Under these circumstances, clinicians should conduct appropriate blood transfusions using the massive transfusion protocol, and make efforts to prepare and apply these protocols to the systems of each hospital in advance. In addition, the effect of massive bleeding on the body highlights the need to understand why fresh frozen plasma and platelets, as well as packed red blood cells (pRBC), are needed during massive transfusion. In hemorrhagic patients, blood pressure maintenance through transfusion is an important part, but above all, efforts to control sustained bleeding by controlling and treating the bleeding itself are more important. This is because patients need to recover their organs after early resuscitation by minimizing the side effects of transfusion. No research has been done to compare the restrictive transfusion and liberal transfusion strategies in patients requiring massive transfusion. On the other hand, various studies suggest that it is more advantageous to apply a liberal blood transfusion strategy in patients with severe or older age. Nevertheless, there has been insufficient research to apply it generally. Therefore, for patients whose resuscitation has been performed by applying a massive transfusion protocol, a reasonable treatment approach would be to shift to a strategy to supplement poor coagulation factors through a goal-directed transfusion. (Korean J Blood Transfus 2020;31:101-108)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116503984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-31DOI: 10.17945/kjbt.2020.31.2.153
Beomki Lee, Yoo Na Chung, HongBi Yu, Tae Yeul Kim, Kwang-Mo Choi, D. Cho
Weak D type 102 allele (RHD*01W.102) carrying a missense variant (c.73A>T, p.Ile25Phe) in exon 1 of the RHD has not been reported in Koreans to date. This is the first report of the weak D type 102 allele in the Korean population. The proposita, a 35-year-old woman, showed a serological weak D phenotype in routine RhD typing. Sequencing of all 10 RHD exons and zygosity testing targeting the hybrid Rhesus box revealed this proposita to harbor the weak D type 102 allele, as well as an RHD deletion (RHD*01W.102/RHD*01N.01). Family studies showed that the weak D type 102 allele was also present in her father and older brother (both assumed to be RHD*01W.102/RHD*01) but not in her mother and oldest brother (both assumed to be RHD*01/RHD*01N.01). In silico analysis of the replacement of isoleucine by phenylalanine at position 25 was done with PolyPhen-2, SIFT, and PROVEAN. While PolyPhen-2 predicted the variant as benign, SIFT and PROVEAN predicted it as damaging and deleterious, respectively, suggesting RHD c.73A>T (I25F) as the cause of serologic weak D phenotype. This patient should be treated as D-negative, when transfusion is needed. (Korean J Blood Transfus 2020;31:153-158)
{"title":"Weak D Type 102 Found in a Family Study: The First Case in Korea","authors":"Beomki Lee, Yoo Na Chung, HongBi Yu, Tae Yeul Kim, Kwang-Mo Choi, D. Cho","doi":"10.17945/kjbt.2020.31.2.153","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.153","url":null,"abstract":"Weak D type 102 allele (RHD*01W.102) carrying a missense variant (c.73A>T, p.Ile25Phe) in exon 1 of the RHD has not been reported in Koreans to date. This is the first report of the weak D type 102 allele in the Korean population. The proposita, a 35-year-old woman, showed a serological weak D phenotype in routine RhD typing. Sequencing of all 10 RHD exons and zygosity testing targeting the hybrid Rhesus box revealed this proposita to harbor the weak D type 102 allele, as well as an RHD deletion (RHD*01W.102/RHD*01N.01). Family studies showed that the weak D type 102 allele was also present in her father and older brother (both assumed to be RHD*01W.102/RHD*01) but not in her mother and oldest brother (both assumed to be RHD*01/RHD*01N.01). In silico analysis of the replacement of isoleucine by phenylalanine at position 25 was done with PolyPhen-2, SIFT, and PROVEAN. While PolyPhen-2 predicted the variant as benign, SIFT and PROVEAN predicted it as damaging and deleterious, respectively, suggesting RHD c.73A>T (I25F) as the cause of serologic weak D phenotype. This patient should be treated as D-negative, when transfusion is needed. (Korean J Blood Transfus 2020;31:153-158)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115338966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-31DOI: 10.17945/kjbt.2020.31.2.141
Jungwon Kang, J. Kang, Dae Ho Ko, M. Youn, So‐Yong Kwon
Background: The Korean Red Cross adopted HIV NAT for blood donor screening in 2005 using a minipool assay. In June 2012, the NAT system was replaced with the individual assay. This study examined the characteristics of HIV NAT reactive blood donors to determine if there was any difference in their features between 10 years ago and later. Methods: This study analyzed the HIV RNA quantitative values and the distribution of HIV subtypes using 118 HIV NAT positive blood donations (37 in 2007, 20 in 2008, 32 in 2017 and 29 in 2018). Results: No significant variations of the quantitative values of HIV RNA and the distribution of HIV subtypes 10 years ago and later were observed. This study failed to produce quantitative values of three samples due to the low titer. The mean titer of HIV RNA of the remaining 115 samples were 5.14×10 IU/mL. The dominant HIV subtype of the HIV NAT reactive donors was B showing 54.2% (64/118). Approximately 5.9% (7/118) of the samples showed the HIV subtype C. Forty-seven samples (39.8%) showed the circulating recombinant form (CRF). Conclusion: The rate of HIV subtype B in this study (54.2%) has decreased compared to the results of the past study (95.2%). Some of the cases showing CRF were identified as B in the past study because CRF3, 8, 9, 14, and 15 are recombinant forms, including subtype B. (Korean J Blood Transfus 2020;31:141-152)
{"title":"Analysis of HIV RNA Genotypes and Quantitative Values of HIV NAT Reactive Blood Donations","authors":"Jungwon Kang, J. Kang, Dae Ho Ko, M. Youn, So‐Yong Kwon","doi":"10.17945/kjbt.2020.31.2.141","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.141","url":null,"abstract":"Background: The Korean Red Cross adopted HIV NAT for blood donor screening in 2005 using a minipool assay. In June 2012, the NAT system was replaced with the individual assay. This study examined the characteristics of HIV NAT reactive blood donors to determine if there was any difference in their features between 10 years ago and later. Methods: This study analyzed the HIV RNA quantitative values and the distribution of HIV subtypes using 118 HIV NAT positive blood donations (37 in 2007, 20 in 2008, 32 in 2017 and 29 in 2018). Results: No significant variations of the quantitative values of HIV RNA and the distribution of HIV subtypes 10 years ago and later were observed. This study failed to produce quantitative values of three samples due to the low titer. The mean titer of HIV RNA of the remaining 115 samples were 5.14×10 IU/mL. The dominant HIV subtype of the HIV NAT reactive donors was B showing 54.2% (64/118). Approximately 5.9% (7/118) of the samples showed the HIV subtype C. Forty-seven samples (39.8%) showed the circulating recombinant form (CRF). Conclusion: The rate of HIV subtype B in this study (54.2%) has decreased compared to the results of the past study (95.2%). Some of the cases showing CRF were identified as B in the past study because CRF3, 8, 9, 14, and 15 are recombinant forms, including subtype B. (Korean J Blood Transfus 2020;31:141-152)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122885213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-31DOI: 10.17945/kjbt.2020.31.2.131
Seong-Eun Ryu, Hyun-Ji Lee, Hyerin Kim, Kyung-Hwa Shin, Hyung-Hoi Kim
Background: An increasing number of blood banks use an automated analyzer in ABO blood typing to reduce the high workload and impact of human error. On the other hand, the automated system often causes ABO discrepancies, where cell and serum typing do not match. Hence, the manual method is used for confirmation. This study evaluated the appropriateness of retesting with the manual method. In addition, the causes of ABO discrepancies were analyzed. Methods: A total of 77,590 blood samples were tested with the AutoVue Innova for ABO typing. Among them, 1280 samples were retested manually due to ABO discrepancies. The causes of the discrepancies were analyzed further through additional tests. The serum reaction grades in both methods were compared. Results: ABO typing of 76,906 samples (99.12%), which included 596 manually confirmed samples could be confirmed by the AutoVue system, while 403 samples (0.52%) continued to yield discrepant results. Weak serum reactions in the AutoVue system were observed, as previously reported. One hundred and thirty samples (66.7%), which were graded 0.5+ in the automated analyzer, yielded a negative serum reaction in the manual method, showing a greater serum reaction with the AutoVue system than with the manual method. Conclusion: The AutoVue Innova performs reliably for blood typing. On the other hand, the manual method is still useful as retesting to address the ABO discrepancies and weak or strong serum reactions. In particular, it is important to confirm samples with 0.5+ grade serum reactions manually. (Korean J Blood Transfus 2020; 31:131-140)
{"title":"Evaluation of the Automated Analyzer AutoVue Innova for Blood Group Typing: Clinical Implementation at a Tertiary Hospital over 2 Years","authors":"Seong-Eun Ryu, Hyun-Ji Lee, Hyerin Kim, Kyung-Hwa Shin, Hyung-Hoi Kim","doi":"10.17945/kjbt.2020.31.2.131","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.131","url":null,"abstract":"Background: An increasing number of blood banks use an automated analyzer in ABO blood typing to reduce the high workload and impact of human error. On the other hand, the automated system often causes ABO discrepancies, where cell and serum typing do not match. Hence, the manual method is used for confirmation. This study evaluated the appropriateness of retesting with the manual method. In addition, the causes of ABO discrepancies were analyzed. Methods: A total of 77,590 blood samples were tested with the AutoVue Innova for ABO typing. Among them, 1280 samples were retested manually due to ABO discrepancies. The causes of the discrepancies were analyzed further through additional tests. The serum reaction grades in both methods were compared. Results: ABO typing of 76,906 samples (99.12%), which included 596 manually confirmed samples could be confirmed by the AutoVue system, while 403 samples (0.52%) continued to yield discrepant results. Weak serum reactions in the AutoVue system were observed, as previously reported. One hundred and thirty samples (66.7%), which were graded 0.5+ in the automated analyzer, yielded a negative serum reaction in the manual method, showing a greater serum reaction with the AutoVue system than with the manual method. Conclusion: The AutoVue Innova performs reliably for blood typing. On the other hand, the manual method is still useful as retesting to address the ABO discrepancies and weak or strong serum reactions. In particular, it is important to confirm samples with 0.5+ grade serum reactions manually. (Korean J Blood Transfus 2020; 31:131-140)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133943994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-31DOI: 10.17945/kjbt.2020.31.2.159
D. Kim, Kyung-Hee Kim, Y. Seo, P. Park, J. Ahn, J. Seo
In some cases, hematopoietic stem cell transplants (HSCT) show differences in the D antigen. In previous studies, there have been few cases of de novo anti-D alloimmunization, and even rarer cases of serious side effects or the outcomes. De novo anti-D alloimmunization has been reported to occur more frequently in minor D mismatch than in major D mismatch. For the RhD type of blood components, RhD-negative type is recommended in transfusion in RhD mismatch HSCT without anti-D in donors and recipients. But in situations of insufficient RhD-negative blood supply, this study suggests that the RhD type of blood components depends on the patients’ RhD type before transplantation, and it depends on the donors’ RhD type after transplantation, and an RhD-positive platelet transfusion may be available. (Korean J Blood Transfus 2020;31:159-164)
{"title":"Transfusion in RhD Mismatch Hematopoietic Stem Cell Transplantation","authors":"D. Kim, Kyung-Hee Kim, Y. Seo, P. Park, J. Ahn, J. Seo","doi":"10.17945/kjbt.2020.31.2.159","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.159","url":null,"abstract":"In some cases, hematopoietic stem cell transplants (HSCT) show differences in the D antigen. In previous studies, there have been few cases of de novo anti-D alloimmunization, and even rarer cases of serious side effects or the outcomes. De novo anti-D alloimmunization has been reported to occur more frequently in minor D mismatch than in major D mismatch. For the RhD type of blood components, RhD-negative type is recommended in transfusion in RhD mismatch HSCT without anti-D in donors and recipients. But in situations of insufficient RhD-negative blood supply, this study suggests that the RhD type of blood components depends on the patients’ RhD type before transplantation, and it depends on the donors’ RhD type after transplantation, and an RhD-positive platelet transfusion may be available. (Korean J Blood Transfus 2020;31:159-164)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129300161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-30DOI: 10.17945/kjbt.2020.31.1.70
Hyungsuk Kim, Dae-Hyun Ko
ABO-incompatible solid organ transplantation (ABOi TPL) is a widely accepted treatment option for treating end-stage renal or liver diseases. Although the appropriate selection of the ABO blood group for transfusion is a key step for successful ABOi TPL, there are no evidence-based guidelines to cope with this issue. In this letter, we suggest appropriate blood selection criteria for ABOi TPL based on the basic principles of ABO incompatibility. For major mismatched ABOi TPL, red blood cells (RBCs) should be of the organ recipient’s ABO group, while platelets (PLTs) and plasma products should be of the donor’s ABO group. For the bidirectional mismatched cases, it is desirable to select recipient type RBCs and group AB PLTs and plasma products. (Korean J Blood Transfus 2020;31:70-72)
{"title":"Transfusion in ABO-Incompatible Solid Organ Transplantation","authors":"Hyungsuk Kim, Dae-Hyun Ko","doi":"10.17945/kjbt.2020.31.1.70","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.1.70","url":null,"abstract":"ABO-incompatible solid organ transplantation (ABOi TPL) is a widely accepted treatment option for treating end-stage renal or liver diseases. Although the appropriate selection of the ABO blood group for transfusion is a key step for successful ABOi TPL, there are no evidence-based guidelines to cope with this issue. In this letter, we suggest appropriate blood selection criteria for ABOi TPL based on the basic principles of ABO incompatibility. For major mismatched ABOi TPL, red blood cells (RBCs) should be of the organ recipient’s ABO group, while platelets (PLTs) and plasma products should be of the donor’s ABO group. For the bidirectional mismatched cases, it is desirable to select recipient type RBCs and group AB PLTs and plasma products. (Korean J Blood Transfus 2020;31:70-72)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133572249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-30DOI: 10.17945/kjbt.2020.31.1.43
S. Kim, G. Bae, Hye Ryun Lee
a computerized order system in February 2018. Physicians should select the indication during transfusion order. In January 2019, the warning pop-up additionally applied for informing whether or not the coagulation test results correspond to FFP transfusion indications. We investigated the effects of a new applied program on the appropriateness of FFP transfusion. Methods: By comparing the appropriateness of transfusion before applying the transfusion indication data-entry, we investigated whether there were improvements of appropriateness after applying the transfusion indication data-entry and after applying the warning pop-up. We compared the percentages of performing pre-transfusion coagulation tests and transfusion among FFP requests before and after applying the warning pop-up. Results: After applying the transfusion indication data-entry, the appropriateness improved from 54.5% to 66.7%. The appropriateness of the surgery department was the lowest compared with that of the medical departments and emergency departments. The warning pop-up would be effective to induce pre-transfusion coagulation tests from surgery departments and emergency department. However, there was no further improvement in the appropriateness. Many requests from the surgery departments did not lead to transfusion. As the results of the analysis conducted by dividing each department that belonged to surgery departments, we could determine the wrong transfusion practice specific to each department. Conclusion: The transfusion indication data-entry contributed to improving the appropriateness of FFP transfusion. Department-specific education and real-time auditing are needed for further improvement. (Korean 2020;31:43-54)
{"title":"The Effect of the Transfusion Indication Verification Program on the Appropriateness of Fresh Frozen Plasma Transfusion","authors":"S. Kim, G. Bae, Hye Ryun Lee","doi":"10.17945/kjbt.2020.31.1.43","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.1.43","url":null,"abstract":"a computerized order system in February 2018. Physicians should select the indication during transfusion order. In January 2019, the warning pop-up additionally applied for informing whether or not the coagulation test results correspond to FFP transfusion indications. We investigated the effects of a new applied program on the appropriateness of FFP transfusion. Methods: By comparing the appropriateness of transfusion before applying the transfusion indication data-entry, we investigated whether there were improvements of appropriateness after applying the transfusion indication data-entry and after applying the warning pop-up. We compared the percentages of performing pre-transfusion coagulation tests and transfusion among FFP requests before and after applying the warning pop-up. Results: After applying the transfusion indication data-entry, the appropriateness improved from 54.5% to 66.7%. The appropriateness of the surgery department was the lowest compared with that of the medical departments and emergency departments. The warning pop-up would be effective to induce pre-transfusion coagulation tests from surgery departments and emergency department. However, there was no further improvement in the appropriateness. Many requests from the surgery departments did not lead to transfusion. As the results of the analysis conducted by dividing each department that belonged to surgery departments, we could determine the wrong transfusion practice specific to each department. Conclusion: The transfusion indication data-entry contributed to improving the appropriateness of FFP transfusion. Department-specific education and real-time auditing are needed for further improvement. (Korean 2020;31:43-54)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127180636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-30DOI: 10.17945/kjbt.2020.31.1.1
Y. Lim, D. Seo, Y. Hwang.
The scientific interest in transfusion medicine as related to COVID19 can be summarized in three important points 1) How can we identify asymptomatic COVID19 infected potential blood donors from healthy donors, and if the asymptomatic COVID19 infected person has donated blood and it has been transfused, how will it affect the transfused patient? 2) What affect will COVID19 have on blood establishments and medical institutions that use blood? 3) How will convalescent plasma from recovered COVID-19 patients be collected and then be used for patients in need of it? Since COVID19 has a negative effect on blood transfusion and blood management, well developed lines of communication and cooperation from blood establishments, medical institutions, government agencies, and people are urgently needed to overcome the impact of this negative effect
{"title":"How Does COVID19 Affect Blood Transfusion and Blood Management?","authors":"Y. Lim, D. Seo, Y. Hwang.","doi":"10.17945/kjbt.2020.31.1.1","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.1.1","url":null,"abstract":"The scientific interest in transfusion medicine as related to COVID19 can be summarized in three important points 1) How can we identify asymptomatic COVID19 infected potential blood donors from healthy donors, and if the asymptomatic COVID19 infected person has donated blood and it has been transfused, how will it affect the transfused patient? 2) What affect will COVID19 have on blood establishments and medical institutions that use blood? 3) How will convalescent plasma from recovered COVID-19 patients be collected and then be used for patients in need of it? Since COVID19 has a negative effect on blood transfusion and blood management, well developed lines of communication and cooperation from blood establishments, medical institutions, government agencies, and people are urgently needed to overcome the impact of this negative effect","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132463299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-30DOI: 10.17945/kjbt.2020.31.1.5
Hyun Ok Kim, Y. Cha, Q. Park, E. Choi, Y. Lim, D. Seo, Y. Hwang.
Suggestions for Specialization and Enhancing Capacity in National Blood Services Hyun Ok Kim, M.D., Young Joo Cha, M.D., Quehn Park, M.D., Eun Kyung Choi, M.D., Young Ae Lim, M.D., Dong Hee Seo, M.D., Yoo-Sung Hwang, M.D. Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul; Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul; Armed Forces Medical Research Institute, Daejeon; Department of Medical Education Center, Kyungpook National University School of Medicine, Daegu; Department of Laboratory Medicine, Ajou University School of Medicine, Suwon; LabGenomics Medical Research Institute, Seongnam; Hanmaeum Blood Center, Gwacheon, Korea
对国家血液服务专业化和能力提升的建议:Hyun Ok Kim, M.D.， Young Joo Cha, M.D.， Quehn Park, M.D.， Eun Kyung Choi, M.D.， Young Ae Lim, M.D.， Dong Hee Seo, M.D.， Yoo-Sung Hwang, M.D.延世大学医学院检验医学科，首尔;中央大学医学院检验医学科，首尔;军队医学研究所，大田;庆北大学医学院医学教育中心，大邱;亚洲大学医学院检验医学科，水原;LabGenomics医学研究所，城南;韩国果川市韩心血液中心
{"title":"Suggestions for Specialization and Enhancing Capacity in National Blood Services","authors":"Hyun Ok Kim, Y. Cha, Q. Park, E. Choi, Y. Lim, D. Seo, Y. Hwang.","doi":"10.17945/kjbt.2020.31.1.5","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.1.5","url":null,"abstract":"Suggestions for Specialization and Enhancing Capacity in National Blood Services Hyun Ok Kim, M.D., Young Joo Cha, M.D., Quehn Park, M.D., Eun Kyung Choi, M.D., Young Ae Lim, M.D., Dong Hee Seo, M.D., Yoo-Sung Hwang, M.D. Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul; Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul; Armed Forces Medical Research Institute, Daejeon; Department of Medical Education Center, Kyungpook National University School of Medicine, Daegu; Department of Laboratory Medicine, Ajou University School of Medicine, Suwon; LabGenomics Medical Research Institute, Seongnam; Hanmaeum Blood Center, Gwacheon, Korea","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132557033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：