{"title":"Discovering the efficacy and mechanism of Chinese herbal medicine for distal symmetric polyneuropathy via integrating meta-analysis and network pharmacology analysis","authors":"Tong Wu, Zunjiang Li, Li-hong Yang, Shao-nan Liu, Jing Chen, Wei Zhu, Xin-feng Guo","doi":"10.53388/mhm2022a1121001","DOIUrl":"https://doi.org/10.53388/mhm2022a1121001","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79915111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The mechanism of Chuanxiong Rhizoma on glaucomatous optic nerve injury based on network pharmacology and molecular docking","authors":"An-Qi Yuan, Bing-Yu Wang, Lin-Jing Peng, H. Du","doi":"10.53388/mhm2023008","DOIUrl":"https://doi.org/10.53388/mhm2023008","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88635500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To provide a scientific basis for identifying Richardia scabra with the help of pharmacognosy parameters, which has never been done before. Methods: Roots, stems, and leaves of R. scabra were collected for pharmacognostic studies involving source identification, character observation, microscopic evaluation, phytochemical screening, ultraviolet spectrum analysis, as well as DNA barcoding analysis. Results: The results showed that it had strong microscopic characters, so it could be used to identify R scabra. Phytochemical study showed the presence of carbohydrates, tannins, and proteins from water extract, and the data related to moisture, ash content, and molecular pharmacognosy were obtained. Conclusion: The established method in this study is easy and accurate, which provides a reference basis for its further development and utilization.
{"title":"Pharmacognostical Studies of Richardia scabera L.","authors":"Shan Fan, Wen-Feng Weng, Sheng-Guo Ji","doi":"10.53388/mhm2023016","DOIUrl":"https://doi.org/10.53388/mhm2023016","url":null,"abstract":"Objective: To provide a scientific basis for identifying Richardia scabra with the help of pharmacognosy parameters, which has never been done before. Methods: Roots, stems, and leaves of R. scabra were collected for pharmacognostic studies involving source identification, character observation, microscopic evaluation, phytochemical screening, ultraviolet spectrum analysis, as well as DNA barcoding analysis. Results: The results showed that it had strong microscopic characters, so it could be used to identify R scabra. Phytochemical study showed the presence of carbohydrates, tannins, and proteins from water extract, and the data related to moisture, ash content, and molecular pharmacognosy were obtained. Conclusion: The established method in this study is easy and accurate, which provides a reference basis for its further development and utilization.","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79529350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chenming He, Ling-Hung Lin, Xiaoxiang Cui, Fei Li, B. Fang
{"title":"Exploring the mechanism of action of Wuzhuyu Decoction for vascular headache based on network pharmacology and molecular docking","authors":"Chenming He, Ling-Hung Lin, Xiaoxiang Cui, Fei Li, B. Fang","doi":"10.53388/mhm2023009","DOIUrl":"https://doi.org/10.53388/mhm2023009","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"601 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77354370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.53388/mhm2023a0113001
Xin Han, Yi-Tong Huang, Chang Liu, Qing Liu, Shidong Wang
{"title":"The efficacy and safety of anti-humidification traditional Chinese medicine in the treatment of viral pneumonia: A meta-analysis","authors":"Xin Han, Yi-Tong Huang, Chang Liu, Qing Liu, Shidong Wang","doi":"10.53388/mhm2023a0113001","DOIUrl":"https://doi.org/10.53388/mhm2023a0113001","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87731673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Toosendan Fructus before and after stir-frying process extract on CYP450 enzyme activities in rats in vivo and vitro by cocktail probe drug method","authors":"Yu-Feng Hu, Siddique Ma, Menglin Wang, Shuanghui Shi, Xiaotong Wei, Mingrui Jiang, Huinan Wang, Jingqiu Zhang, Qiangang Liu, Ying-Zi Wang","doi":"10.53388/mhm2023006","DOIUrl":"https://doi.org/10.53388/mhm2023006","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80946173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaoyan Xie, Yao Lu, Xushan Chen, Gulizeba Muhetaer, Hao Tao, Hang Li, Han-Jiao Liu
Pulmonary fibrosis (PF) is a chronic, progressive, and irreversible pulmonary interstitial disease with unclear pathogenesis. Currently, there are few treatment options for managing PF. Inhalation therapy, as a routine treatment for respiratory diseases, is being used to study the treatment of PF. Some herbal medicines and their active ingredients have been reported to have anti-PF effects. This review aims to provide an overview of the latest developments in inhalation therapy, focusing on the utilization of chemical medicines and herbal medicines for the treatment of PF in both clinical practice and basic research. The inhalation of chemical drugs such as pirfenidone, nintedanib, N-acetylcysteine, and interferon-γ has been shown to demonstrate anti-PF effects. Additionally, the inhalation of various natural products derived from herbal medicines, encompassing polyphenols, alkaloids, flavonoids, saponins, terpenoids, and herbal extracts, contributes to the therapeutic management of PF through diverse mechanisms. The inhalation of both chemical and herbal medicines presents promising advantages in the treatment of PF. Further clinical trials are required to investigate the effectiveness, safety, and mechanism of action of inhalation therapy utilizing natural products derived from herbal medicines.
{"title":"Inhalation therapy for pulmonary fibrosis: chemical medicines and herbal medicines","authors":"Xiaoyan Xie, Yao Lu, Xushan Chen, Gulizeba Muhetaer, Hao Tao, Hang Li, Han-Jiao Liu","doi":"10.53388/mhm2023014","DOIUrl":"https://doi.org/10.53388/mhm2023014","url":null,"abstract":"Pulmonary fibrosis (PF) is a chronic, progressive, and irreversible pulmonary interstitial disease with unclear pathogenesis. Currently, there are few treatment options for managing PF. Inhalation therapy, as a routine treatment for respiratory diseases, is being used to study the treatment of PF. Some herbal medicines and their active ingredients have been reported to have anti-PF effects. This review aims to provide an overview of the latest developments in inhalation therapy, focusing on the utilization of chemical medicines and herbal medicines for the treatment of PF in both clinical practice and basic research. The inhalation of chemical drugs such as pirfenidone, nintedanib, N-acetylcysteine, and interferon-γ has been shown to demonstrate anti-PF effects. Additionally, the inhalation of various natural products derived from herbal medicines, encompassing polyphenols, alkaloids, flavonoids, saponins, terpenoids, and herbal extracts, contributes to the therapeutic management of PF through diverse mechanisms. The inhalation of both chemical and herbal medicines presents promising advantages in the treatment of PF. Further clinical trials are required to investigate the effectiveness, safety, and mechanism of action of inhalation therapy utilizing natural products derived from herbal medicines.","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83929091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Drug combination based on synergistic effect is commonly used in clinical practice, especially in the application of traditional medicine. Exploring the combination mechanism could help to better utilize this synergistic advantage. However, current research focuses more on the efficacy enhancing of drugs, while ignoring the toxicity reducing effects. Here, we established two drug synergy patterns based on the different situations of drugs and targets, in order to better illuminate the synergistic mechanism of drugs.
{"title":"Novel patterns for drug synergistic mechanism research","authors":"Tian-Long Liu, Min-Na Liu, Yi Ding","doi":"10.53388/mhm2023017","DOIUrl":"https://doi.org/10.53388/mhm2023017","url":null,"abstract":"Drug combination based on synergistic effect is commonly used in clinical practice, especially in the application of traditional medicine. Exploring the combination mechanism could help to better utilize this synergistic advantage. However, current research focuses more on the efficacy enhancing of drugs, while ignoring the toxicity reducing effects. Here, we established two drug synergy patterns based on the different situations of drugs and targets, in order to better illuminate the synergistic mechanism of drugs.","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"88 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136206900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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