Laboratory examiners before giving blood transfusions (PretransfusionTesting) is a vital part of the transfusion activity. Incompatible Crossmatching blood tests on patients is consistent if we had to crossmatching one or more of the one or all of the positive so that blood is stated compatible with the patient. The gel test method has many advantages compared to the tubulating method other than the halting factor time. The gel test procedures have also been simpler, more practical, and easier results reading done. The goal of this study to identify the output of crossmatching receipts on the geltest method of 2019 in Indonesian Redcross of Klaten, this research method using a descriptive design with a sectional cross approach. And data retrieval using secondary data. The results shows the number of inconsistencies in patients of 116 cases. As many as 57% (66) incompatible crossmatching major minor and autocontrol of 43%(50) found a type of compatible major. The conclution are that in Indonesian Redcross of Klaten found most frequently in the diagnosis of anemia 59% (69) patients. The result of incompatible minor and positive autocontrol 57% more than compatible major 43%. Incompatible crossmatching receipts per month in the high Indonesian Redcross of Klaten is in April of 27 patients or 23%.
{"title":"Profile of Incompatible Crossmatching Examination Results in Patients With Gel Test Method","authors":"Eni Ruwiyanti","doi":"10.31983/jlm.v2i1.6983","DOIUrl":"https://doi.org/10.31983/jlm.v2i1.6983","url":null,"abstract":"Laboratory examiners before giving blood transfusions (PretransfusionTesting) is a vital part of the transfusion activity. Incompatible Crossmatching blood tests on patients is consistent if we had to crossmatching one or more of the one or all of the positive so that blood is stated compatible with the patient. The gel test method has many advantages compared to the tubulating method other than the halting factor time. The gel test procedures have also been simpler, more practical, and easier results reading done. The goal of this study to identify the output of crossmatching receipts on the geltest method of 2019 in Indonesian Redcross of Klaten, this research method using a descriptive design with a sectional cross approach. And data retrieval using secondary data. The results shows the number of inconsistencies in patients of 116 cases. As many as 57% (66) incompatible crossmatching major minor and autocontrol of 43%(50) found a type of compatible major. The conclution are that in Indonesian Redcross of Klaten found most frequently in the diagnosis of anemia 59% (69) patients. The result of incompatible minor and positive autocontrol 57% more than compatible major 43%. Incompatible crossmatching receipts per month in the high Indonesian Redcross of Klaten is in April of 27 patients or 23%.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129077107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dengue hemorrhagic fever (DHF) is an acute infectious disease caused by the dengue virus. This virus is transmitted by mosquitoes from the genus Aedes, for example Aedes aegypti and Aedes albopictus. Patients who are infected will have symptoms in the form of a mild to high fever, accompanied by headaches, pain in the eyes, muscles and joints, and spontaneous bleeding. DHF in Indonesia, has become a public health problem for the last 45 years since 1968. These cases are spread across 33 provinces and in 436 districts / cities out of 497 districts / cities (88%) in Indonesia. The number of people with Dengue Hemorrhagic Fever (DHF) tends to increase. The laboratory chooses to use a blood cell counter or a hematology analyzer to count the patient's blood cell count. The results of laboratory examinations with platelet counts in dengue fever patients were obtained 19 (14.84%) samples of patients with platelets d below 100,000 per micrometer (mcL) from 128 patients from January to March 2019. With 2 days of fever patients were 44 people. , 37 patients had fever for 4 days, and 5 fever patients were 47, in normal numbers and brought to a normal range of 150,000-400,000/ mmᶾ.
{"title":"Platelet Count in Dengue Fever Patients","authors":"Niken Meiriyani","doi":"10.31983/JLM.V2I1.6895","DOIUrl":"https://doi.org/10.31983/JLM.V2I1.6895","url":null,"abstract":"Dengue hemorrhagic fever (DHF) is an acute infectious disease caused by the dengue virus. This virus is transmitted by mosquitoes from the genus Aedes, for example Aedes aegypti and Aedes albopictus. Patients who are infected will have symptoms in the form of a mild to high fever, accompanied by headaches, pain in the eyes, muscles and joints, and spontaneous bleeding. DHF in Indonesia, has become a public health problem for the last 45 years since 1968. These cases are spread across 33 provinces and in 436 districts / cities out of 497 districts / cities (88%) in Indonesia. The number of people with Dengue Hemorrhagic Fever (DHF) tends to increase. The laboratory chooses to use a blood cell counter or a hematology analyzer to count the patient's blood cell count. The results of laboratory examinations with platelet counts in dengue fever patients were obtained 19 (14.84%) samples of patients with platelets d below 100,000 per micrometer (mcL) from 128 patients from January to March 2019. With 2 days of fever patients were 44 people. , 37 patients had fever for 4 days, and 5 fever patients were 47, in normal numbers and brought to a normal range of 150,000-400,000/ mmᶾ.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128428525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Histopathological examination is a routine examination process for each tissue in the anatomic pathology laboratory. The stages in making histology preparations are fixation stages. The type of solution that can be used as a fixative solution other than 10% NBF is Carnoy's solution. Carnoy's solution is a fixative solution with a relatively fast fixation process of about 1-4 hours. The advantages of Carnoy's solution can lyse erythrocytes and dissolve lipids, have the ability to maintain cell nuclei, and retain glycogen. The purpose of this study was to determine the histology of the liver tissue preparations of mice (Mus Musculus) which were fixed using Carnoy's solution with time variations of 4 hours, 8 hours, and 12 hours. This is an observational research with descriptive research design criteria. The results of the histology of the liver tissue preparations of mice (Mus Musculus) which were fixed using the 10% NBF solution group obtained 100% good preparations. In the Carnoy solution group with a time of 4 hours, it gave 2.2% results of poor preparations and 97.78% of good preparations. While the treatment group with Carnoy's solution with a time of 8 hours obtained as many as 11.11% of preparations that were not good and 88.89% of good preparations. and in the Carnoy solution group with a time of 12 hours, there were 44.44% of the poor preparations and 55.56% of the good preparations.
{"title":"Histology of Mice (Mus Musculus) Liver Tissue Fixed with Carnoy's Solution With Variation of 4 Hours, 8 Hours and 12 Hours","authors":"Arin Dwi Afrida, Djoko Priyatno","doi":"10.31983/jlm.v3i1.7920","DOIUrl":"https://doi.org/10.31983/jlm.v3i1.7920","url":null,"abstract":"Histopathological examination is a routine examination process for each tissue in the anatomic pathology laboratory. The stages in making histology preparations are fixation stages. The type of solution that can be used as a fixative solution other than 10% NBF is Carnoy's solution. Carnoy's solution is a fixative solution with a relatively fast fixation process of about 1-4 hours. The advantages of Carnoy's solution can lyse erythrocytes and dissolve lipids, have the ability to maintain cell nuclei, and retain glycogen. The purpose of this study was to determine the histology of the liver tissue preparations of mice (Mus Musculus) which were fixed using Carnoy's solution with time variations of 4 hours, 8 hours, and 12 hours. This is an observational research with descriptive research design criteria. The results of the histology of the liver tissue preparations of mice (Mus Musculus) which were fixed using the 10% NBF solution group obtained 100% good preparations. In the Carnoy solution group with a time of 4 hours, it gave 2.2% results of poor preparations and 97.78% of good preparations. While the treatment group with Carnoy's solution with a time of 8 hours obtained as many as 11.11% of preparations that were not good and 88.89% of good preparations. and in the Carnoy solution group with a time of 12 hours, there were 44.44% of the poor preparations and 55.56% of the good preparations.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133830984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heavy metal lead can cause poisoning or accumulate in human body. Truck drivers spend more a lot of time on the road due to the slow movement of trucks due to carrying heavy loads causing exposure to lead on the highway. Lead enters through the breath and is excreted in the hair. Truck drivers spend more a lot of time on the road, especially trucks that have more than 4 wheels because the load they carry is heavy so it takes time to travel and can be exposed lead on the road. It also allows researchers to easily collect hair samples. longer the work, they get higher lead levels in the human body. After conducting a survey, many truck drivers opened their windows. This happens, maybe some of the Air Cooler (AC) trucks are not working because maybe some of the trucks are too old. This allows truck drivers to be exposed to lead from the air. In addition, PPE (Personal Protective Equipment) is also important such as masks to reduce exposure to lead from the respiratory tract.
{"title":"Lead Levels in Truck Driver's Hair","authors":"Zahran Arya Zidan, Teguh Budiharjo","doi":"10.31983/jlm.v3i1.7919","DOIUrl":"https://doi.org/10.31983/jlm.v3i1.7919","url":null,"abstract":"Heavy metal lead can cause poisoning or accumulate in human body. Truck drivers spend more a lot of time on the road due to the slow movement of trucks due to carrying heavy loads causing exposure to lead on the highway. Lead enters through the breath and is excreted in the hair. Truck drivers spend more a lot of time on the road, especially trucks that have more than 4 wheels because the load they carry is heavy so it takes time to travel and can be exposed lead on the road. It also allows researchers to easily collect hair samples. longer the work, they get higher lead levels in the human body. After conducting a survey, many truck drivers opened their windows. This happens, maybe some of the Air Cooler (AC) trucks are not working because maybe some of the trucks are too old. This allows truck drivers to be exposed to lead from the air. In addition, PPE (Personal Protective Equipment) is also important such as masks to reduce exposure to lead from the respiratory tract.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125982080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Venny Patricia, Wawan Sofwan Zaini, A. Yani, Siti Atikah
Infectious diseases are a problem for public health and can increase patient morbidity and mortality. Bacteria that cause infectious diseases include Streptococcus pyogenes and Proteus mirabilis. Inappropriate use of antibiotics can cause resistance problems and the effects of undesirable drugs. Jamblang (Syzygium cumini) leaf extract can be used as a natural antibacterial drug. There is a study showing the content of active compounds in the leaves of Jamblang are Flavonoids, tannins, alkaloids, and saponins are components of chemical compounds that are suspected as antibacterial. This study aims to determine the antibacterial activity of Jamblang leaf extract against Streptococcus pyogenes and Proteus mirabilis bacteria. The method used is the Minimum Inhibitory Concentration method using well diffusion. The study used Jamblang leaf extract with various concentrations of 10%, 20%, 30%, and 40%, the test bacteria used were Streptococcus pyogenes and Proteus mirabilis, using positive control of chloramphenicol, and negative control of 10% DMSO. The results showed that Jamblang leaf extract can inhibit the growth of Streptococcus pyogenes and Proteus mirabilis bacteria in all concentrations. In the Kruskall Wallis Non-Parametric statistical test the two bacteria obtained P 0.05.In Streptococcus pyogenes bacteria the value of P = 0.031, and Proteus mirabilis bacteria the value of P = 0.015. These results indicate a real difference in this study.
{"title":"Inhibitory Test of Jamblang Leaf Extract (Syzygium Cumini (L.) Skeels) Against the Growth of Streptococcus Pyogenes and Proteus Mirabilis Bacteria","authors":"Venny Patricia, Wawan Sofwan Zaini, A. Yani, Siti Atikah","doi":"10.31983/jlm.v3i1.7932","DOIUrl":"https://doi.org/10.31983/jlm.v3i1.7932","url":null,"abstract":"Infectious diseases are a problem for public health and can increase patient morbidity and mortality. Bacteria that cause infectious diseases include Streptococcus pyogenes and Proteus mirabilis. Inappropriate use of antibiotics can cause resistance problems and the effects of undesirable drugs. Jamblang (Syzygium cumini) leaf extract can be used as a natural antibacterial drug. There is a study showing the content of active compounds in the leaves of Jamblang are Flavonoids, tannins, alkaloids, and saponins are components of chemical compounds that are suspected as antibacterial. This study aims to determine the antibacterial activity of Jamblang leaf extract against Streptococcus pyogenes and Proteus mirabilis bacteria. The method used is the Minimum Inhibitory Concentration method using well diffusion. The study used Jamblang leaf extract with various concentrations of 10%, 20%, 30%, and 40%, the test bacteria used were Streptococcus pyogenes and Proteus mirabilis, using positive control of chloramphenicol, and negative control of 10% DMSO. The results showed that Jamblang leaf extract can inhibit the growth of Streptococcus pyogenes and Proteus mirabilis bacteria in all concentrations. In the Kruskall Wallis Non-Parametric statistical test the two bacteria obtained P 0.05.In Streptococcus pyogenes bacteria the value of P = 0.031, and Proteus mirabilis bacteria the value of P = 0.015. These results indicate a real difference in this study.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124624406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Type 2 diabetes mellitus with chronic hyperglycemia can cause a hypoxic environment in the renal interstitium and can cause kidney disorders (diabetic nephropathy), this can lead to decreased kidney function and the production of erythropoietin produced by peritubular fibroblasts is disrupted, and hemoglobin is not formed optimally and occurs anemia. Thei purposei ofi thisi studyi wasi toi determinei hemoglobini levelsi in patients withi typei 2i diabetesi mellitusi in RSUD. K.R.M.T Wongsonegoro Semarang. This is a descriptive quantitative study, the data comes from the medical records of patients with typei 2i diabetesi mellitusi withi complicationsi ofi diabetici nephropathyi at RSUD K.R.M.T Wongsonegoro Semarang as many as 40 samples with non-probability samplingi itechnique. The results showed that there were 20 men who had decreased hemoglobin levels and 1 person who had normal hemoglobin levels. Meanwhile, in women, 17 people had decreased hemoglobin levels and 2 people had normal hemoglobin levels. Based on the age category, the most were the early elderly as many as 15 people and the least in the late teens and early adults each as many as 2 people. Meanwhile, based on the average level of anemia, more experienced moderate levels of anemia. Hemoglobin levels in patients with type. 2i. diabetesi. mellitusi. withi. complicationsi. ofi. diabetici. nephropathyi. at RSUD K.R.M.T Wongsonegoro Semarang were 40 samples, on average they had low hemoglobin levels.
{"title":"Hemoglobin Levels in Type 2 Diabetes Mellitus Patients","authors":"Wahyu Anita Khoirin, Rodhi Hartono","doi":"10.31983/jlm.v3i1.7918","DOIUrl":"https://doi.org/10.31983/jlm.v3i1.7918","url":null,"abstract":"Type 2 diabetes mellitus with chronic hyperglycemia can cause a hypoxic environment in the renal interstitium and can cause kidney disorders (diabetic nephropathy), this can lead to decreased kidney function and the production of erythropoietin produced by peritubular fibroblasts is disrupted, and hemoglobin is not formed optimally and occurs anemia. Thei purposei ofi thisi studyi wasi toi determinei hemoglobini levelsi in patients withi typei 2i diabetesi mellitusi in RSUD. K.R.M.T Wongsonegoro Semarang. This is a descriptive quantitative study, the data comes from the medical records of patients with typei 2i diabetesi mellitusi withi complicationsi ofi diabetici nephropathyi at RSUD K.R.M.T Wongsonegoro Semarang as many as 40 samples with non-probability samplingi itechnique. The results showed that there were 20 men who had decreased hemoglobin levels and 1 person who had normal hemoglobin levels. Meanwhile, in women, 17 people had decreased hemoglobin levels and 2 people had normal hemoglobin levels. Based on the age category, the most were the early elderly as many as 15 people and the least in the late teens and early adults each as many as 2 people. Meanwhile, based on the average level of anemia, more experienced moderate levels of anemia. Hemoglobin levels in patients with type. 2i. diabetesi. mellitusi. withi. complicationsi. ofi. diabetici. nephropathyi. at RSUD K.R.M.T Wongsonegoro Semarang were 40 samples, on average they had low hemoglobin levels.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115320168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tuberculosis is an infectious infection caused by Mycobacterium tuberculosis. Anti Tuberculosis drug therapy given has side effects, one of which is hepatotoxicity.. The purpose of this study was to describe the levels of SGOT, SGPT, and total bilirubin in pulmonary tuberculosis patients based on the characteristics of gender and age. This type of research is descriptive observational with a case study approach. Data retrieval using purposive sampling of 120 patients was carried out by analyzing data on medical records. The results of the study in the intensive stage of treatment showed an increase in SGOT for 12 males and females an average of 71 U/L and 93 U/L. The SGPT of 12 men and 14 women averaged 86 U/L and 92 U/L. Total bilirubin in 10 men and 12 women averaged 1.58 mg/dl and 1.68 mg/dl, respectively. The increase in SGOT in 15 patients 26-45 years, 8 patients 46-65 years, and 2 patients 65 years averaged 79 U/L, 70 U/L, and 97 U/L. SGPT occurred in 15 patients 26-45 years, 8 patients 46-65 years, and 3 patients 65 years with mean levels of 82 U/L, 97 U/L, and 96 U/L. Total bilirubin occurred in 15 patients 26-45 years, 5 patients 46-65 years, and 2 patients 65 years with mean levels of 1.72 mg/dl, 1.38 mg/dl, and 1.57 mg/dl. , whereas in the advanced stage of treatment, all patients had normal levels of SGOT, SGPT, and total bilirubin with an average of 27 U/L, 29 U/L, and 0.41 mg/dl.
{"title":"Total SGOT, SGPT and Bilirubin Levels in Pulmonary Tuberculosis Patients","authors":"Titan Melina Putri","doi":"10.31983/jlm.v3i1.7917","DOIUrl":"https://doi.org/10.31983/jlm.v3i1.7917","url":null,"abstract":"Tuberculosis is an infectious infection caused by Mycobacterium tuberculosis. Anti Tuberculosis drug therapy given has side effects, one of which is hepatotoxicity.. The purpose of this study was to describe the levels of SGOT, SGPT, and total bilirubin in pulmonary tuberculosis patients based on the characteristics of gender and age. This type of research is descriptive observational with a case study approach. Data retrieval using purposive sampling of 120 patients was carried out by analyzing data on medical records. The results of the study in the intensive stage of treatment showed an increase in SGOT for 12 males and females an average of 71 U/L and 93 U/L. The SGPT of 12 men and 14 women averaged 86 U/L and 92 U/L. Total bilirubin in 10 men and 12 women averaged 1.58 mg/dl and 1.68 mg/dl, respectively. The increase in SGOT in 15 patients 26-45 years, 8 patients 46-65 years, and 2 patients 65 years averaged 79 U/L, 70 U/L, and 97 U/L. SGPT occurred in 15 patients 26-45 years, 8 patients 46-65 years, and 3 patients 65 years with mean levels of 82 U/L, 97 U/L, and 96 U/L. Total bilirubin occurred in 15 patients 26-45 years, 5 patients 46-65 years, and 2 patients 65 years with mean levels of 1.72 mg/dl, 1.38 mg/dl, and 1.57 mg/dl. , whereas in the advanced stage of treatment, all patients had normal levels of SGOT, SGPT, and total bilirubin with an average of 27 U/L, 29 U/L, and 0.41 mg/dl.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"37 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134392559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liver disfunction is characterized by increased levels of SGOT and SGPT. The mechanism of liver disfunction by anti-tuberculosis drug (ATD) is not yet clearly known, but several research mention the occurrence of hepatotoxicity which caused by direct effect or through the complex production of drug enzyme which have consequences in cell disfunction as well as membrane disfunction. Hepatotoxicity due to ATD does not occur in each patient, but it could cause liver injury. research objective to find out the description of examination of SGOT and SGPT levels in patients of pulmonary tuberculosis. The research type was descriptive using medical records data and laboratory data of RSUP patients of pulmonary TB in January-March 2020. Research results : the normal SGOT levels in men 6-33 U/L as much as 63,33%, and SGOT normal 50-66 U/L as much as 2,35%. The normal SGOT levels in women 10-25 U/L as much as 25,88%, and SGOT normal in women 15-63 U/L as much as 8,24%. The normal SGPT levels in men 3-43 U/L as much as 62,35%, and SGPT normal 55-65 U/L as much as 3,53%. The normal SGPT levels in women 7-29 U/L as much as 34,12%. Hepatotoxicity based on SGOT levels as many as 9 people (10,59%), namely 2 men (elderly and old man) and 7 women (adolescent, adult, and elderly). Hepatotoxicity based on SGPT levels as many as 3 people (3,53%) in elderly and old man.
{"title":"Profile of SGOT And SGPT Level Check in Pulmonary Tuberculosis Patients","authors":"Siti Chairini, Djoko Priyatno","doi":"10.31983/jlm.v2i2.7712","DOIUrl":"https://doi.org/10.31983/jlm.v2i2.7712","url":null,"abstract":"Liver disfunction is characterized by increased levels of SGOT and SGPT. The mechanism of liver disfunction by anti-tuberculosis drug (ATD) is not yet clearly known, but several research mention the occurrence of hepatotoxicity which caused by direct effect or through the complex production of drug enzyme which have consequences in cell disfunction as well as membrane disfunction. Hepatotoxicity due to ATD does not occur in each patient, but it could cause liver injury. research objective to find out the description of examination of SGOT and SGPT levels in patients of pulmonary tuberculosis. The research type was descriptive using medical records data and laboratory data of RSUP patients of pulmonary TB in January-March 2020. Research results : the normal SGOT levels in men 6-33 U/L as much as 63,33%, and SGOT normal 50-66 U/L as much as 2,35%. The normal SGOT levels in women 10-25 U/L as much as 25,88%, and SGOT normal in women 15-63 U/L as much as 8,24%. The normal SGPT levels in men 3-43 U/L as much as 62,35%, and SGPT normal 55-65 U/L as much as 3,53%. The normal SGPT levels in women 7-29 U/L as much as 34,12%. Hepatotoxicity based on SGOT levels as many as 9 people (10,59%), namely 2 men (elderly and old man) and 7 women (adolescent, adult, and elderly). Hepatotoxicity based on SGPT levels as many as 3 people (3,53%) in elderly and old man.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122680177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes mellitus type 2 (DM Type-2) is a metabolic disease which characterized by hyperglycemia due to failure of insulin secretion, insulin action or both. If DM is not handled properly, then it will arise complications in various organs of the body. The criterias of DM control including HbA1c levels and lipid fractions. Lipid pattern in patients with DM type 2 is very dependent on HbA1c control. High HbA1c is associated with high triglycerides and cholesterol. Research objective to find out the description of Hba1c, cholesterol and triglyceride levels in patients of DM type 2 at the Outpatient Poly of RSUD Tidar Magelang. Research method the research type was descriptive with observational design. Primary data were obtained from levels measurements of HbA1c, cholesterol and triglycerides.. The normal HbA1c levels 4-5,80%, good control 6,1-6,5%, moderate 6,6-7,8%, bad 8,8-14,1% respectively as much as 65,96%, 12,77%, 10,64%, and 10,90%. The normal cholesterol levels 100-160 mg/dL, moderate 200-220 mg/dL, and high 250-300 mg/dL, respectively 74,47%, 10,64%, and 14,89%. The normal triglyceride levels 70-140 mg/dL, high limit 150-165 mg/dL, and high 200-252 mg/dL respectively as much as 63,83%, 19,15% and 17,02%. Based on the age of normal HbA1c levels as much as 65,96%, normal cholesterol 74,47%, and triglycerides 63,83%. The levels of HbA1c, cholesterol, and triglycerides were mostly normal in age groups of elderly, and male. The high levels of HbA1c, cholesterol, and triglycerides were more common in elderly than in other age groups.
{"title":"Profile of HbA1c, Cholesterol and Triglyceride in Type 2 Diabetes Mellitus","authors":"Gunardi Gunardi","doi":"10.31983/jlm.v2i2.7722","DOIUrl":"https://doi.org/10.31983/jlm.v2i2.7722","url":null,"abstract":"Diabetes mellitus type 2 (DM Type-2) is a metabolic disease which characterized by hyperglycemia due to failure of insulin secretion, insulin action or both. If DM is not handled properly, then it will arise complications in various organs of the body. The criterias of DM control including HbA1c levels and lipid fractions. Lipid pattern in patients with DM type 2 is very dependent on HbA1c control. High HbA1c is associated with high triglycerides and cholesterol. Research objective to find out the description of Hba1c, cholesterol and triglyceride levels in patients of DM type 2 at the Outpatient Poly of RSUD Tidar Magelang. Research method the research type was descriptive with observational design. Primary data were obtained from levels measurements of HbA1c, cholesterol and triglycerides.. The normal HbA1c levels 4-5,80%, good control 6,1-6,5%, moderate 6,6-7,8%, bad 8,8-14,1% respectively as much as 65,96%, 12,77%, 10,64%, and 10,90%. The normal cholesterol levels 100-160 mg/dL, moderate 200-220 mg/dL, and high 250-300 mg/dL, respectively 74,47%, 10,64%, and 14,89%. The normal triglyceride levels 70-140 mg/dL, high limit 150-165 mg/dL, and high 200-252 mg/dL respectively as much as 63,83%, 19,15% and 17,02%. Based on the age of normal HbA1c levels as much as 65,96%, normal cholesterol 74,47%, and triglycerides 63,83%. The levels of HbA1c, cholesterol, and triglycerides were mostly normal in age groups of elderly, and male. The high levels of HbA1c, cholesterol, and triglycerides were more common in elderly than in other age groups.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122373410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liver disfunction is characterized by increased levels of SGOT and SGPT. The mechanism of liver disfunction by anti-tuberculosis drug (ATD) is not yet clearly known, but several research mention the occurrence of hepatotoxicity which caused by direct effect or through the complex production of drug enzyme which have consequences in cell disfunction as well as membrane disfunction. Hepatotoxicity due to ATD does not occur in each patient, but it could cause liver injury. research objective to find out the description of examination of SGOT and SGPT levels in patients of pulmonary tuberculosis. The research type was descriptive using medical records data and laboratory data of RSUP patients of pulmonary TB in January-March 2020. Research results : the normal SGOT levels in men 6-33 U/L as much as 63,33%, and SGOT normal 50-66 U/L as much as 2,35%. The normal SGOT levels in women 10-25 U/L as much as 25,88%, and SGOT normal in women 15-63 U/L as much as 8,24%. The normal SGPT levels in men 3-43 U/L as much as 62,35%, and SGPT normal 55-65 U/L as much as 3,53%. The normal SGPT levels in women 7-29 U/L as much as 34,12%. Hepatotoxicity based on SGOT levels as many as 9 people (10,59%), namely 2 men (elderly and old man) and 7 women (adolescent, adult, and elderly). Hepatotoxicity based on SGPT levels as many as 3 people (3,53%) in elderly and old man.
{"title":"Profile of SGOT and SGPT levels in Patients with Pulmonary Tuberculosis","authors":"Siti Chairini, W. Widodo","doi":"10.31983/jlm.v2i1.6266","DOIUrl":"https://doi.org/10.31983/jlm.v2i1.6266","url":null,"abstract":"Liver disfunction is characterized by increased levels of SGOT and SGPT. The mechanism of liver disfunction by anti-tuberculosis drug (ATD) is not yet clearly known, but several research mention the occurrence of hepatotoxicity which caused by direct effect or through the complex production of drug enzyme which have consequences in cell disfunction as well as membrane disfunction. Hepatotoxicity due to ATD does not occur in each patient, but it could cause liver injury. research objective to find out the description of examination of SGOT and SGPT levels in patients of pulmonary tuberculosis. The research type was descriptive using medical records data and laboratory data of RSUP patients of pulmonary TB in January-March 2020. Research results : the normal SGOT levels in men 6-33 U/L as much as 63,33%, and SGOT normal 50-66 U/L as much as 2,35%. The normal SGOT levels in women 10-25 U/L as much as 25,88%, and SGOT normal in women 15-63 U/L as much as 8,24%. The normal SGPT levels in men 3-43 U/L as much as 62,35%, and SGPT normal 55-65 U/L as much as 3,53%. The normal SGPT levels in women 7-29 U/L as much as 34,12%. Hepatotoxicity based on SGOT levels as many as 9 people (10,59%), namely 2 men (elderly and old man) and 7 women (adolescent, adult, and elderly). Hepatotoxicity based on SGPT levels as many as 3 people (3,53%) in elderly and old man.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131109919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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