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Maintaining surgical skills in an era of declining trauma surgery cases: insights from 12 years of trauma surgery experience in a surgical residency program facility. 在创伤手术病例减少的时代保持手术技能:来自外科住院医师项目设施12年创伤手术经验的见解。
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-12-03 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2024-001650
Tadao Kubota

Background: Unlike in Western countries, trauma center consolidation has not progressed in Japan. This raises the question of who are the appropriate providers for the decreased number of trauma surgeries. Emergency surgeons performing trauma surgeries lack sufficient cases for skill refinement, while on the other hand, surgeons performing elective surgeries face the dilemma of not being able to handle trauma across organs due to subspecialization. In this context, our institution has deliberately not pursued subspecialization and has been addressing various trauma surgery cases by regularly handling a wide range of general surgery fields.

Objective and methods: We examined the types, sites, target organs, and procedures of trauma surgeries performed under general anesthesia at our institution from April 2012 to December 2023. Additionally, we investigated the content and annual trends of non-trauma surgeries performed during the same period to assess the appropriateness of general surgeons handling trauma surgeries and to consider future sustainability.

Results: Trauma surgeries averaged around six cases per year, accounting for approximately 1% of the total surgeries performed. Most surgeries were related to abdominal organs, which could mostly be managed with techniques from the field of gastrointestinal surgery. Although there were fewer cases, it seemed possible to handle surgeries for neck, chest, and vascular trauma through routine clinical practice such as thyroid surgery, lung and mediastinal tumor surgeries, and peripheral vascular surgeries. Issues identified include a decrease in non-gastrointestinal cases as subspecialization progresses, and an increasing proportion of laparoscopic surgeries leading to a rise in inexperienced young surgeons in open surgery.

Conclusion: Handling trauma surgeries with fewer cases seemed possible by broadly addressing the scope of general surgery in routine clinical practice.

背景:与西方国家不同,日本的创伤中心巩固并没有取得进展。这就提出了谁是减少创伤手术数量的合适提供者的问题。急诊外科医生进行创伤手术缺乏足够的病例来提高技能,而另一方面,外科医生进行选择性手术面临着由于亚专业化而无法处理跨器官创伤的困境。在这种情况下,我们的机构故意不追求亚专业化,并通过定期处理广泛的普通外科领域来解决各种创伤手术病例。目的与方法:回顾我院2012年4月至2023年12月全麻下创伤手术的类型、部位、靶器官及手术方式。此外,我们调查了同期进行的非创伤性手术的内容和年度趋势,以评估普通外科医生处理创伤手术的适当性并考虑未来的可持续性。结果:创伤手术平均每年约6例,约占手术总数的1%。多数手术涉及腹部器官,多采用胃肠外科技术。虽然病例较少,但通过常规的临床实践,如甲状腺手术、肺和纵隔肿瘤手术、周围血管手术,似乎可以处理颈部、胸部和血管创伤的手术。确定的问题包括随着亚专业化的发展,非胃肠道病例的减少,以及腹腔镜手术比例的增加导致开放手术中缺乏经验的年轻外科医生的增加。结论:在常规临床实践中,拓宽普外科的范围,减少创伤手术病例是可能的。
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引用次数: 0
Using elective surgical experience to supplement the waning trauma operative experience: is it truly enough? 利用选择性手术经验来补充逐渐减少的创伤手术经验:这真的足够吗?
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-12-03 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2025-002147
Madhuri Nagaraj, Joanna W Etra, Clay Cothren Burlew
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引用次数: 0
Performance of individual audit filters in predicting opportunities for improvement in adult trauma patients. 个别审计过滤器在预测成人创伤患者改善机会中的表现。
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-11-27 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2025-001808
Josef Al-Khalili, Jonatan Attergrim, Johanna Berg, Kelvin Szolnoky, Martin Gerdin Wärnberg

Background: Trauma audit filters, based on standards of care, serve as quality indicators and screening tools for patient cases to be assessed at interdisciplinary morbidity and mortality conferences. These conferences aim to identify potential opportunities for improvement in the care of trauma patients. This study aimed to determine the performance of individual audit filters in predicting opportunities for improvement and their relevance as screening tools for morbidity and mortality conferences.

Methods: We conducted a single-center registry-based retrospective cohort study based on registered data collected between 2013 and 2022 from the Karolinska University Hospital in Sweden. Performance was measured using sensitivity, specificity, positive predictive value, negative predictive value, and Matthews correlation coefficient for 10 audit filters used at the Karolinska University Hospital.

Results: Our analysis included 8309 patients. Audit filters demonstrated inconsistent agreement with opportunities for improvement with a Matthews correlation coefficient ranging from -0.088 (95% CI -0.129 to -0.044) for "Injury Severity Score >15 and no team activation" to 0.092 (95% CI 0.058 to 0.126) for "> 60 min until first major intervention." The Matthews correlation coefficient for all audit filters combined was 0.118 (95% CI 0.104 to 0.131).

Conclusion: No individual audit filter or combination thereof performed well in predicting opportunities for improvement, which suggests that the current method of screening for morbidity and mortality conferences should be revisited.

Level of evidence: Level III, prognostic/epidemiological.

背景:创伤审计过滤器,以护理标准为基础,作为质量指标和筛选工具,在跨学科发病率和死亡率会议上评估患者病例。这些会议的目的是确定潜在的机会,以改善创伤患者的护理。本研究旨在确定个别审计过滤器在预测改进机会方面的表现及其作为发病率和死亡率会议筛选工具的相关性。方法:我们进行了一项基于单中心登记的回顾性队列研究,该研究基于2013年至2022年在瑞典卡罗林斯卡大学医院收集的登记数据。使用卡罗林斯卡大学医院使用的10种审计过滤器的敏感性、特异性、阳性预测值、阴性预测值和马修斯相关系数来衡量绩效。结果:我们的分析包括8309例患者。审计过滤器显示与改进机会的一致性不一致,马修斯相关系数范围从“伤害严重程度评分>5,没有团队激活”的-0.088 (95% CI -0.129至-0.044)到“> 60分钟,直到第一次主要干预”的0.092 (95% CI 0.058至0.126)。所有审计过滤器的马修斯相关系数为0.118 (95% CI 0.104至0.131)。结论:没有单独的审计过滤器或其组合在预测改进机会方面表现良好,这表明应该重新审视目前的发病率和死亡率会议筛选方法。证据等级:III级,预后/流行病学。
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引用次数: 0
Concomitant antithrombotic therapy and substance use in older adult trauma patients: a secondary evaluation of an EAST Multicenter Trial. 老年创伤患者的伴随抗血栓治疗和药物使用:一项EAST多中心试验的二次评价。
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-11-27 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2024-001664
Abby Sheffield, Arnav Mahajan, Sharven Taghavi, Danielle Tatum, Marie L Crandall, Brian K Yorkgitis

Background: The concurrent use of antithrombotic agents and intoxicants in older trauma patients (≥65) poses a potential risk for adverse outcomes. As the prevalence of substance use among older adults rises, understanding the impact of these combined factors on trauma outcomes is crucial. This study evaluates the impact of combined intoxication and antithrombotic use on trauma outcomes in older adults.

Methods: We conducted a secondary analysis of data from an Eastern Association for the Surgery of Trauma-sponsored multicenter prospective observational study involving 15 Level I and II trauma centers from February 2018 to June 2019. Included patients were on antithrombotic therapy and had blood alcohol concentration (BAC) and/or urine toxicology (UT) samples collected at trauma evaluation. Intoxication was defined as BAC >0.08 mg/dL or a positive UT. Patient demographics, injury characteristics, and outcomes were analyzed using linear and logistic regression models.

Results: Of 2793 trauma patients on antithrombotics, 862 met inclusion criteria, with 155 (18.0%) testing positive for intoxicants. Positive tests were associated with younger age (74 years vs 79 years, p<0.001), lower Charlson Comorbidity Index (4 vs 5, p<0.001), and similar Injury Severity Scores (6 vs 9, p=0.38). Patients with positive tests had more penetrating mechanisms of injury (11.0% vs 3.7%, p=0.01) and similar hospital stays (3 days vs 4 days, p=0.311). ICU admission rates were lower (32.9% vs 42.2%, p=0.041), with no difference in ICU length of stay or mortality. Higher ICU admissions (p=0.039) and increased ICU stays were seen in those on two substances (OR: 5.26, 95% CI 0.76 to 9.76, p=0.022).

Conclusions: Older trauma patients on antithrombotic therapy with concurrent intoxicant use did not exhibit worse clinical outcomes, despite higher rates of penetrating injuries and polysubstance use. These findings underscore the importance of tailored discharge planning and comprehensive care strategies for this vulnerable population.

Level of evidence: Level III, prognostic/epidemiological.

背景:老年创伤患者(≥65岁)同时使用抗血栓药物和中毒药物有潜在的不良后果风险。随着老年人药物使用的流行率上升,了解这些综合因素对创伤结果的影响至关重要。本研究评估了联合中毒和抗血栓药物使用对老年人创伤结果的影响。方法:我们对2018年2月至2019年6月由东部创伤外科协会赞助的一项涉及15个一级和二级创伤中心的多中心前瞻性观察性研究的数据进行了二次分析。纳入的患者接受抗血栓治疗,并在创伤评估时收集血液酒精浓度(BAC)和/或尿液毒理学(UT)样本。中毒定义为BAC 0 0.08 mg/dL或UT阳性。使用线性和逻辑回归模型分析患者人口统计学、损伤特征和结果。结果:在接受抗栓治疗的2793例创伤患者中,862例符合纳入标准,其中155例(18.0%)中毒检测阳性。结论:尽管穿透性损伤和多种药物使用的发生率较高,但接受抗血栓治疗的老年创伤患者并没有表现出更差的临床结果。这些发现强调了为这一弱势群体制定量身定制的出院计划和综合护理策略的重要性。证据等级:III级,预后/流行病学。
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引用次数: 0
Characteristics of a three-pronged continuum of care model for hospital-based violence intervention. 医院暴力干预三管齐下连续护理模式的特点。
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-11-27 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2025-001869
Christine Castater, Lucy Hart, Ariana Metchik, Kenya Jackson, Robert Wright, Nkosi Cave, Chee'Tara Alexander, Jacquel Clemons, Patrice Sarumi, Randi N Smith

Gun violence is a health crisis that disparately affects non-Hispanic black males, where victims get stuck in a cycle of recurrent violence perpetuated by systemic inequities. Hospital-based violence intervention programs (HVIPs) decrease violent reinjury by addressing social drivers/determinants of health. Many HVIPs solely focus on inpatient interventions. We designed a novel three-pronged continuum of care model: the Bedside, Clinic, Community (BCC) model as a longitudinal approach for equitable service delivery. Our HVIP, Interrupting Violence in Youth and Young Adults (IVYY), serves victims of community violence. The first pillar provides 'Bedside' care for inpatients; the second uses a multidisciplinary 'Clinic' to address medical and social concerns; and the third 'Community' pillar consists of partnerships with local grassroots organizations. Throughout the intervention, IVYY provides pathways for education, mental health, housing, employment, financial, and legal aid. In the first year of service, IVYY enrolled 299 patients who received 1168 inpatient visits. 26.1% were considered high risk and were seen in the IVYY clinic. Community partners provided innumerable resources to IVYY participants. By implementing the BCC model, we provide longitudinal care that addresses patient needs at every stage of their journey.

枪支暴力是一种健康危机,对非西班牙裔黑人男性的影响不同,受害者陷入了由系统性不平等造成的反复暴力循环。基于医院的暴力干预方案(HVIPs)通过处理健康的社会驱动因素/决定因素来减少暴力再伤害。许多hvip只关注住院治疗。我们设计了一种新颖的三管齐下的连续护理模式:床边、诊所、社区(BCC)模式,作为公平服务提供的纵向方法。我们的HVIP,阻断青少年暴力(IVYY),服务于社区暴力的受害者。第一个支柱为住院病人提供“床边”护理;第二种是利用多学科的“诊所”来解决医疗和社会问题;第三个“社区”支柱包括与当地基层组织的伙伴关系。在整个干预过程中,IVYY提供了教育、心理健康、住房、就业、财政和法律援助的途径。在服务的第一年,IVYY招募了299名患者,接受了1168次住院治疗。26.1%为高危,就诊于IVYY门诊。社区合作伙伴为IVYY参与者提供了无数资源。通过实施BCC模式,我们提供纵向护理,以满足患者在其旅程的每个阶段的需求。
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引用次数: 0
Effect of anticoagulation on isolated traumatic brain injury mortality using TQIP database: a propensity score analysis stratified by head injury severity. 使用TQIP数据库抗凝对孤立性创伤性脑损伤死亡率的影响:按脑损伤严重程度分层的倾向评分分析。
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-11-23 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2025-001839
Narong Kulvatunyou, Zachary M Bauman, Alberto D Ramirez, Benjamin Cordy, William S Sherman, Gregory Jarrin, Allison Tompeck, Paul Dabrowski, Ara Feinstein, Natasha Keric

Introduction: The impact of anticoagulation (AC) on traumatic brain injury (TBI) outcomes remains varied in the literature. Previous studies often relied on single-center data, small sample sizes, or lacked adjustments for key confounding variables. This study used the population-based Trauma Quality Improvement Program (TQIP) database to analyze the effect of AC on isolated TBI mortality, hypothesizing that AC's impact varies with TBI severity.

Methods: This retrospective cohort study analyzed data from 2020 to 2021 TQIP database. Patients with isolated TBI were identified using International Classification of Diseases, 10th revision codes. Exclusions included patients <18 years, penetrating trauma, and non-head injuries with Abbreviated Injury Scale (AIS) score >3. The majority of patients taking AC were in their 50s and above; therefore, they were stratified into AC and non-AC cohorts. Propensity score analysis adjusted for age, gender, and head AIS, stratified by TBI severity (mild, moderate, severe). Primary outcomes were in-hospital mortality and neurosurgical intervention (NSI), including craniotomy and intracranial pressure monitoring. Statistical analyses were performed using Stata V.17.0, with significance at p<0.05.

Results: Among 118,775 patients with isolated TBI, 96,802 were >50 years, with 26,444 (27%) taking AC. Unadjusted mortality was higher in the AC group (6%) compared with the non-AC group (3%; ∆3%, p<0.001). Adjusted mortality differences showed significant AC effects in mild (∆1.3%, 95% CI 1.04% to 1.57%, p<0.001) and moderate TBI (∆7.9%, 95% CI 4.46% to 11.43%, p<0.001), but not severe TBI (∆3.14%, 95% CI 0.07% to 7.04%, p=0.11). No significant AC effect on NSI was observed after adjustment.

Discussion: Preinjury AC increases mortality in patients with isolated TBI, with the magnitude of its impact varying by TBI severity. Future studies should explore AC's influence on intracranial blood volume and progression to further elucidate its role in TBI outcomes.

Level of evidence: Level 3.

在文献中,抗凝(AC)对创伤性脑损伤(TBI)结果的影响仍然各不相同。以前的研究往往依赖于单中心数据,小样本量,或者缺乏对关键混杂变量的调整。本研究使用基于人群的创伤质量改善计划(TQIP)数据库来分析AC对孤立性TBI死亡率的影响,并假设AC的影响随TBI严重程度而变化。方法:本回顾性队列研究分析了2020 - 2021年TQIP数据库的数据。孤立性脑外伤患者采用《国际疾病分类》第10版编码进行鉴定。排除患者3例。大多数服用AC的患者年龄在50岁及以上;因此,他们被分为交流组和非交流组。倾向评分分析调整了年龄、性别和头部AIS,按TBI严重程度(轻度、中度、重度)分层。主要结局是住院死亡率和神经外科干预(NSI),包括开颅和颅内压监测。使用Stata V.17.0进行统计分析,结果具有重要意义:在118,775例孤立性TBI患者中,96,802例为50岁,其中26,444例(27%)服用AC。AC组的未调整死亡率(6%)高于非AC组(3%);∆3%,p讨论:损伤前AC增加孤立性TBI患者的死亡率,其影响程度因TBI严重程度而异。未来的研究应探讨AC对颅内血容量和进展的影响,以进一步阐明其在TBI预后中的作用。证据等级:三级。
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引用次数: 0
Road crashes: a scourge on African lives! 道路交通事故:非洲人生命的祸害!
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-11-19 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2025-002151
Timothy Craig Hardcastle
{"title":"Road crashes: a scourge on African lives!","authors":"Timothy Craig Hardcastle","doi":"10.1136/tsaco-2025-002151","DOIUrl":"10.1136/tsaco-2025-002151","url":null,"abstract":"","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"10 4","pages":"e002151"},"PeriodicalIF":2.2,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12636939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145588873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pinpointing a social determinant of surgical disease: the impact of language-concordant care on outcomes for trauma patients. 精确定位外科疾病的社会决定因素:语言和谐护理对创伤患者结果的影响。
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-11-19 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2025-002117
Zachary Enumah, Latoya Stewart, Alejandro V García
{"title":"Pinpointing a social determinant of surgical disease: the impact of language-concordant care on outcomes for trauma patients.","authors":"Zachary Enumah, Latoya Stewart, Alejandro V García","doi":"10.1136/tsaco-2025-002117","DOIUrl":"10.1136/tsaco-2025-002117","url":null,"abstract":"","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"10 4","pages":"e002117"},"PeriodicalIF":2.2,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12636972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145588790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors influencing Vizient length of stay index after surgical stabilization of rib fractures (SSRF). 影响肋骨骨折手术稳定术后住院时间指数的因素。
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-11-19 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2025-001827
Najiha Bilal Farooqi, Mobeen Farooqi, Lakshika Tennakoon, Ruoxue Wu, Jamie Tung, Joseph D Forrester

Background: Surgical stabilization of ribs (SSRF) has been associated with shorter durations of mechanical ventilation and hospital and intensive care unit lengths of stay (LOS). Vizient is a national organization that provides detailed quality data, including the LOS index, benchmarked to comparable-sized and acuity health systems.

Aims: Identify factors associated with shorter and expected LOS index among patients undergoing SSRF.

Method: We performed a retrospective review of all adult trauma patients who underwent SSRF from November 2021 to May 2023 at our American College of Surgeons Level 1 trauma center. Logistic regression on key patient characteristics was performed to assess associations with LOS index <1.

Results: 37 (69%) patients had an LOS index <1, whereas 17 (32%) had an expected LOS index >1. Patients with a LOS index <1 had lower injury severity scores (ISS) (16.9 SD=11.2 vs 21.7 SD=10.5, p=0.029) and were more commonly working full-time preinjury (n=16, 43%) compared with patients with a LOS index >1 (n=8, 47%, p=0.042). LOS index >1 was also associated with higher body mass index (BMI), government insurance, and polytrauma.

Conclusion: Focused, early interventions in patients with higher BMI, polytrauma, and higher ISS scores may help lower the LOS index among patients undergoing SSRF.

背景:手术稳定肋骨(SSRF)与较短的机械通气时间以及住院和重症监护病房的住院时间(LOS)有关。Vizient是一个全国性组织,提供详细的质量数据,包括LOS指数,以同等规模的健康系统为基准。目的:确定与SSRF患者较短的预期LOS指数相关的因素。方法:我们对2021年11月至2023年5月在美国外科医师学会一级创伤中心接受SSRF治疗的所有成人创伤患者进行了回顾性研究。对关键患者特征进行Logistic回归以评估与LOS指数的关系。结果:37例(69%)患者的LOS指数为1。LOS指数为1的患者(n=8, 47%, p=0.042)。LOS指数bbb1也与较高的身体质量指数(BMI)、政府保险和多发创伤有关。结论:对高BMI、多发创伤和高ISS评分的患者进行有针对性的早期干预可能有助于降低SSRF患者的LOS指数。
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引用次数: 0
Association of antiplatelet agents and intracranial hemorrhage in geriatric emergency department patients with head trauma from a fall. 抗血小板药物与老年急诊科患者颅内出血的关系
IF 2.2 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-11-18 eCollection Date: 2025-01-01 DOI: 10.1136/tsaco-2025-001863
Grace Wang, Shan W Liu, Mike Wells, Gabriella Engstrom, Patrick G Hughes, Lisa M Clayton, Scott M Alter, Joshua J Solano, Joshua A Torres, Timothy P Buckley, Richard D Shih

Background: Older adults have the highest incidence of traumatic brain injury and are often on antiplatelet therapy. This study examines the association between preinjury antiplatelet agent use and intracranial hemorrhage in geriatric emergency department (ED) patients with blunt head injury from a fall.

Methods: We conducted a secondary analysis of the GREAT STOP project, a large prospective study of geriatric ED patients who sustained head trauma. This project enrolled patients from two level one trauma centers over 1 year beginning 1 August 2019. Trained research associates enrolled patients who met study criteria. The primary outcome was intracranial hemorrhage. Rates of intracranial hemorrhage were compared between patients who were prescribed preinjury antiplatelet agents versus those who were not on any antiplatelet or anticoagulant therapy.

Results: 3709 patients were included in the final analysis. Overall, 12.8% (475) had intracranial hemorrhage, and 6.4% (237) had a significant intracranial hemorrhage. Delayed intracranial hemorrhage occurred in 0.3% (10) of patients with one of these classified as a significant intracranial hemorrhage (1). Patients on aspirin or dual antiplatelet therapy had increased adjusted ORs of intracranial hemorrhage compared with patients not on antiplatelet therapy (1.4, 95% CI 1.1 to 1.8; and 1.7, 95% CI 1.1 to 2.6, respectively). Use of P2Y12 inhibitors alone did not show this effect (1.0, 95% CI 0.6 to 1.6).

Conclusions: In geriatric ED patients who have sustained blunt head trauma from a fall, aspirin and especially dual antiplatelet therapy are associated with a significant risk of intracranial hemorrhage, while P2Y12 antiplatelet agents do not appear to carry this risk. The benefits from the use of these agents in older patients need to be weighed against their risk for fall and potential fall-related injury such as intracranial hemorrhage.

背景:老年人的创伤性脑损伤发生率最高,经常接受抗血小板治疗。本研究探讨了损伤前抗血小板药物的使用与老年急诊科(ED)患者因跌倒造成的钝性头部损伤的颅内出血之间的关系。方法:我们对GREAT STOP项目进行了二次分析,这是一项针对持续头部创伤的老年ED患者的大型前瞻性研究。从2019年8月1日开始,该项目招募了来自两个一级创伤中心的患者,为期一年。训练有素的研究助理招募了符合研究标准的患者。主要结局为颅内出血。比较损伤前服用抗血小板药物的患者与未服用抗血小板或抗凝治疗的患者颅内出血的发生率。结果:3709例患者纳入最终分析。总体而言,12.8%(475例)有颅内出血,6.4%(237例)有显著颅内出血。0.3%(10)的患者发生迟发性颅内出血,其中一项被归类为严重颅内出血(1)。与未接受抗血小板治疗的患者相比,接受阿司匹林或双重抗血小板治疗的患者颅内出血的调整后ORs增加(分别为1.4,95% CI 1.1 - 1.8;和1.7,95% CI 1.1 - 2.6)。单独使用P2Y12抑制剂没有显示出这种效果(1.0,95% CI 0.6至1.6)。结论:在因跌倒而遭受钝性头部创伤的老年ED患者中,阿司匹林和特别是双重抗血小板治疗与颅内出血的显著风险相关,而P2Y12抗血小板药物似乎没有这种风险。在老年患者中使用这些药物的好处需要与他们跌倒和潜在的跌倒相关损伤(如颅内出血)的风险进行权衡。
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引用次数: 0
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Trauma Surgery & Acute Care Open
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