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Mitigating the risk of low-titer group O-positive whole blood resuscitation in females of childbearing potential: toward a systems-based approach. 降低具有生育能力的女性低滴度o型阳性全血复苏的风险:朝着基于系统的方法发展。
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-12-15 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001687
Elizabeth P Crowe, Steven M Frank, Matthew J Levy
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引用次数: 0
Not too short, not too long, but just right: does pre-arrival time impact team performance? 不要太短,也不要太长,但要恰到好处:到达前的时间会影响团队绩效吗?
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-12-15 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001688
Jacob Schriner, Ryan Dumas
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引用次数: 0
Polytrauma patient with a massive pulmonary embolism and ischemic stroke in the setting of a patent foramen ovale. 多发创伤患者在卵圆孔未闭的情况下发生大量肺栓塞和缺血性中风。
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-12-15 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001596
Ibraheem Hamzat, Sabrina Wang, Samuel Osei, Takeyoshi Ota, David A Hampton
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引用次数: 0
Community of trauma care partnering with stakeholders to improve injury outcomes: survey analysis and panel development. 创伤护理社区与利益相关者合作改善伤害结果:调查分析和小组开发。
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-12-11 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001466
Rachel D Appelbaum, Anna B Newcomb, Michelle A Price, Katherine Joseph, Ashley N Moreno, Morgan Hennessy, Princess Fortin, Pam J Bixby, Sue Prentiss, Alexandra McConnell-Hill, Rochelle Flayter, Rochelle A Dicker, Rosemary A Kozar, Elliott R Haut, Deborah M Stein

Background: In June 2021, the Injury Research Engagement Project (I-REP) was established. In 2022, we preformed focus group analysis with patients/caregiver and researchers that resulted in themes in preferences, motivations, and best practices to increase participation in trauma research. The importance of trust and well-established relationships was common across all groups. In this study, we aimed to further evaluate preferences regarding research procedures and outcomes, and develop a panel for sustained patient engagement.

Methods: We performed a multiphase, mixed methods study to elicit trauma stakeholders' perspectives regarding aspects of research. Previously published phase 1 involved focus group analysis. Phase 2 vignette-based surveys and phase 3 panel formation are described here. One survey was completed by patients/caregivers, and the second by trauma researchers. We compared the responses using independent t-tests. This was followed by a webinar and development of an I-REP panel of patients/caregivers.

Results: 60 patients/caregivers and 114 researchers participated in the online surveys, with completion rates of 68% and 69%, respectively. The majority of patients/caregivers were >45 years, female (66.7%), and >3 years out from their or their family member's injury (68.6%). The majority of the researchers were >35 years and male (56.2%). Participants were asked to gauge their perceptions of different research scenarios. The analysis identified themes emerging across groups. Several survey findings differed from phase 1, including motivations to participate (payment) and consent preferences (timing, approach). Racial and ethnic demographics of the participants were not collected.

Conclusions: Engaging trauma stakeholders results in research more relevant to patients' needs and priorities. Qualitative engagement methods that intentionally include a more diverse population and determining the appropriate format for specific questions may lead to results that are be more generalizable. The educational webinar was well received, and several participants opted to serve as I-REP panelists to collaborate with trauma researchers moving forward.

Level of evidence: IV.

背景:2021年6月,损伤研究参与项目(I-REP)成立。在2022年,我们对患者/护理人员和研究人员进行了焦点小组分析,得出了偏好、动机和最佳实践的主题,以增加对创伤研究的参与。信任和良好关系的重要性在所有群体中都很普遍。在本研究中,我们旨在进一步评估研究程序和结果的偏好,并开发一个持续患者参与的小组。方法:我们进行了一项多阶段、混合方法的研究,以引出创伤利益相关者对研究方面的观点。先前发布的第一阶段涉及焦点小组分析。这里描述了第2阶段基于视点的调查和第3阶段的面板形成。一项调查由患者/护理人员完成,另一项由创伤研究人员完成。我们使用独立t检验比较了这些反应。随后是网络研讨会和I-REP患者/护理人员小组的发展。结果:60名患者/护理人员和114名研究人员参与了在线调查,完成率分别为68%和69%。大多数患者/照顾者年龄为45岁,女性(66.7%),离其或其家庭成员受伤3年(68.6%)。大多数研究人员年龄在35岁以下,男性占56.2%。参与者被要求评估他们对不同研究场景的看法。分析确定了各群体之间出现的主题。一些调查结果与第一阶段不同,包括参与动机(付款)和同意偏好(时间、方法)。没有收集参与者的种族和民族人口统计数据。结论:参与创伤利益相关者导致研究更相关的患者的需求和优先事项。定性参与方法有意地包括更多样化的人群,并为特定问题确定适当的格式,可能会导致更普遍的结果。这个教育性的网络研讨会受到了很好的欢迎,一些参与者选择作为I-REP小组成员,与创伤研究人员合作。证据等级:四级。
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引用次数: 0
Using trauma video review to search for the Goldilocks pre-activation time. 利用创伤视频回顾来寻找金发姑娘预激活时间。
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-12-11 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001588
Ella Rose Rastegar, Sophia Görgens, Manuel Beltran Del Rio, Elizabeth Nilsson Sjolander, Joseph Landers, Cristy Meyer, Daniel Rolston, Eric Klein, Maria Sfakianos, Matthew Bank, Daniel Jafari

Objectives: We sought to determine the optimal time to pre-activation for trauma team activation that resulted in maximum team efficiency, measured by the time to complete critical actions (TCCAs) during resuscitation. We hypothesized that there exists a time window for trauma team pre-activation that minimizes TCCA.

Methods: This is an exploratory retrospective analysis of video-reviewed traumas at a level 1 trauma center from January 1, 2018 to 28 February, 2022 that received the highest trauma team activation and had a pre-arrival notification. A total of 11 TCCA categories were calculated using video timestamps. To compare TCCAs from different categories, normalized TCCAs (nTCCAs) were calculated by dividing each TCCA by the median time of its category. Pre-activation times were categorized into three groups: long pre-activation (≥8 min), mid pre-activation (≥4 and ≤7 min), and short pre-activation (≥0 and ≤4).

Results: There were 466 video-recorded level 1 trauma activations, which resulted in 2334 TCCAs. Of the 466 activations, 152 occured on the patient's arrival (0 min pre-activation). The majority (425) of patients had a pre-activation time of <7 min. Pre-activation of 4-6 min resulted in all but blood transfusion TCCAs being <15 min. Furthermore, mid pre-activation category corresponded to the most efficient trauma teams, with nTCCAs significantly shorter (median=0.75 (IQR 0.3-1.3)) than long (median=1 (IQR 0.6-2)) or short activation groups (median=1 (IQR 0.6-1.6)). A greater proportion of nTCCAs were shorter than their category median in the mid pre-activation category compared with long and short categories (59.1% vs 48.3% and 40%, respectively; p<0.01).

Conclusions: In this exploratory study, a pre-activation time of 4-7 min is associated with the best team efficiency as measured by TCCAs during trauma team activations. This timeframe may be an optimal window for trauma team activations but needs prospective and external validation.

Level of evidence: Level 4 retrospective exploratory study.

目的:我们试图通过在复苏期间完成关键动作(TCCAs)的时间来确定创伤小组激活的最佳预激活时间,从而达到最大的团队效率。我们假设存在一个创伤小组预激活的时间窗口,使TCCA最小化。方法:对2018年1月1日至2022年2月28日在某一级创伤中心接受最高创伤小组激活并有到达前通知的视频审查创伤进行探索性回顾性分析。使用视频时间戳共计算了11个TCCA类别。为了比较不同类别的TCCA,通过将每个TCCA除以其类别的中位数时间来计算归一化TCCA (ntcca)。预激活时间分为长预激活(≥8 min)、中预激活(≥4 min和≤7 min)和短预激活(≥0 min和≤4 min)三组。结果:视频记录的1级创伤激活466例,tcca 2334例。在466例激活中,152例发生在患者到达时(激活前0分钟)。结论:在这项探索性研究中,在创伤小组激活期间,TCCAs测量的预激活时间为4-7分钟与最佳团队效率相关。这个时间框架可能是创伤小组激活的最佳窗口,但需要前瞻性和外部验证。证据等级:4级回顾性探索性研究。
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引用次数: 0
Evolution of whole blood trauma resuscitation in childbearing age females: practice patterns and trends. 育龄女性全血创伤复苏的演变:实践模式和趋势。
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-12-07 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001587
Alexandra Mp Brito, Mark H Yazer, Jason L Sperry, James F Luther, Stephen R Wisniewski, Frances Guyette, Ernest E Moore, Bryan A Cotton, Laura Vincent, Erin Fox, Jeremy W Cannon, Nicholas Namias, Joseph P Minei, Lee Anne Ammons, Skye Clayton, Martin Schreiber

Background: The use of low titer group O whole blood (LTOWB) for resuscitation of patients with traumatic hemorrhage is becoming increasingly common. Practices regarding the administration of RhD-positive LTOWB to childbearing age females (CBAFs) vary between institutions due to concerns about RhD alloimmunization. This study examined practices related to LTOWB transfusion as they pertain to age and sex.

Methods: This was a secondary analysis of the Shock, Whole blood, and Assessment of TBI (traumatic brain injury) trial, a prospective, multicenter observational cohort study where outcomes following LTOWB transfusion were analyzed at seven level 1 trauma centers between 2018 and 2021, as well as a survey on transfusion practices at these centers conducted in 2023. The proportion of patients who received LTOWB or components was examined over the course of the study and grouped by age and sex, and the RhD group of injured CBAFs was documented.

Results: A total of 1046 patients were evaluated: 130 females aged <50 years (CBAFs), 77 females aged ≥50 years; 661 males aged <50 years, and 178 males aged ≥50 years. Among them, 26.2% of CBAFs received RhD-positive LTOWB, whereas 57.1%-66.3% of other sex/age groups received LTOWB. The proportion of CBAFs who received LTOWB increased significantly throughout the 4 years of this study. Except for older women in years 2 and 4, CBAFs were significantly less likely to receive LTOWB than all other groups for the study period and individual years. Among the 33 CBAFs who received LTOWB and for whom an RhD type was available, 4/33 (12.1%) were RhD-negative, while 9/95 (9.5%) CBAFs who received component therapy were RhD-negative. RhD blood product selection practices varied considerably between institutions.

Conclusions: Many institutions transfused LTOWB to CBAFs. Policies regarding RhD product selection varied. Of the total cohort, the proportion of RhD-negative CBAFs who received LTOWB increased over time but remained lower than all other groups.

Level of evidence: 3.

背景:低效价O型全血(LTOWB)用于外伤性出血患者的复苏越来越普遍。由于对RhD同种异体免疫的关注,各机构对育龄女性(CBAFs)给予RhD阳性LTOWB的做法各不相同。本研究检查了与LTOWB输血有关的实践,因为它们与年龄和性别有关。方法:这是对休克、全血和TBI(创伤性脑损伤)评估试验的二次分析,这是一项前瞻性、多中心观察性队列研究,分析了2018年至2021年7个一级创伤中心LTOWB输血后的结果,以及2023年对这些中心输血实践的调查。在研究过程中,研究人员检查了接受LTOWB或成分治疗的患者比例,并按年龄和性别分组,并记录了CBAFs损伤的RhD组。结果:共评估了1046例患者,其中女性130例,年龄大。结论:许多机构向CBAFs输注LTOWB。关于RhD产品选择的政策各不相同。在整个队列中,rhd阴性cafs接受LTOWB的比例随着时间的推移而增加,但仍低于所有其他组。证据等级:3。
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引用次数: 0
Preparing the future combat surgeon: a survey of the military general surgery trainee GME experience. 培养未来的作战外科医生:对军队普外科学员GME经验的调查。
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-11-26 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001609
Emily W Baird, Joshua Dilday, Daniel Lammers, Matthew D Tadlock, Jennifer M Gurney, Jan O Jansen, John B Holcomb

Abstract:

Introduction: Graduate medical education (GME) lacks a standardized military training program for general surgery residents, and concern exists that they may not be prepared to serve as combat surgeons on training completion. The purpose of this study was to assess military surgery trainee satisfaction with their programs. Our hypothesis was that military residents were not completely confident to care for combat casualties on completion of current GME training.

Methods: We surveyed US Army, Navy, and Air Force general surgery residents and fellows between November 2023 and March 2024 to assess their confidence in managing combat injuries. Queried residents further rate their overall satisfaction with surgical training, perceived level of deployment preparedness and curriculum elements which they thought would be most beneficial to their training.

Results: The survey yielded an overall 43% response rate (132/305) with a response rate of 42% (61/147) from the Army, 56% (44/79) from the Navy, and 34% (27/79) from the Air Force. Most trainees were trained in military medical treatment facility residency programs (n=91, 68.9%) and nearly half of respondents (n=64, 49%) were senior trainees (postgraduate year (PGY)4, PGY5, and fellows). Among all trainees, only two-thirds (n=88, 67%,) thought they were adequately prepared to deploy and operate on military combat casualties by the end of residency but 114 (86%) were satisfied with the training they received during general surgery residency in adult trauma, 103 (78%) in critical care, and 112 (85%) in acute care surgery. However, more than half were unsatisfied with the training they received in obstetric/gynecologic and urologic emergencies (n=72, 55%; and n=67, 51%, respectively).

Conclusion: Although the majority of military surgical residents surveyed are satisfied with their training in adult trauma, critical care, and emergency general surgery, a large number of trainees thought they would not be ready to deploy and manage combat casualties.

Level of evidence: Prognostic and epidemiological, Level IV.

摘要/ Abstract摘要:导读:研究生医学教育(GME)缺乏规范的普外科住院医师军事训练计划,存在培训完成后无法胜任作战外科医生的担忧。本研究的目的是评估军事外科实习生对他们的计划的满意度。我们的假设是,在完成当前的GME训练后,军人居民并没有完全有信心照顾战斗伤亡。方法:我们在2023年11月至2024年3月期间调查了美国陆军、海军和空军的普通外科住院医师和研究员,以评估他们对管理战斗伤害的信心。接受调查的住院医生进一步评价了他们对外科培训的总体满意度、对部署准备的感知水平和他们认为对培训最有益的课程要素。结果:调查的总体回复率为43%(132/305),其中陆军的回复率为42%(61/147),海军的回复率为56%(44/79),空军的回复率为34%(27/79)。大部分受训人员来自军队医疗设施住院医师项目(n=91, 68.9%),近一半(n=64, 49%)是高级受训人员(研究生四年级、五年级和研究员)。在所有受训人员中,只有三分之二(n=88, 67%)认为他们在实习结束时已经为部署和处理军事战斗伤亡做好了充分的准备,但114人(86%)对他们在成人创伤普通外科实习期间接受的培训感到满意,103人(78%)在重症监护,112人(85%)在急性护理外科。然而,超过一半的人对他们在产科/妇科和泌尿科急诊方面接受的培训不满意(n= 72,55%;n=67,分别为51%)。结论:虽然接受调查的大部分军外科住院医师对他们在成人创伤、重症监护和急诊普通外科方面的培训感到满意,但大量受训人员认为他们还没有做好部署和管理战斗伤亡的准备。证据等级:预后和流行病学,四级。
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引用次数: 0
Stop The Falls! A framework for injury prevention outreach for older adults presented by the American Association for the Surgery of Trauma Geriatric Trauma and Injury Prevention Committees. 停止瀑布!美国创伤外科协会老年创伤和损伤预防委员会提出的老年人损伤预防外展框架。
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-11-26 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001487
Tanya Egodage, Thomas K Duncan, Vanessa P Ho, D'Andrea Joseph, Adin Tyler Putnam, Sigrid Burruss, Tasce Bongiovanni, Jennifer Knight-Davis, Sasha D Adams, Elizabeth Gorman, Molly P Jarman, Nasim Ahmed, Asanthi Ratnasekera, Kartik Prabhakaran, Caitlin Cohan, Melissa Hornor, Kristin P Colling, Bellal Joseph

With the increasing age of the population in the USA, fall prevention events to target older patients are imperative. The American Association for the Surgery of Trauma hosted a fall prevention event at the host city of the 2023 Annual Meeting. We review the planning and implementation of this "Stop the Falls" event, in hopes that other institutions may benefit and sustainably effectuate fall prevention events for an increasingly geriatric population.

随着美国人口年龄的增长,针对老年患者的跌倒预防活动势在必行。美国创伤外科协会在2023年年会的主办城市举办了一次预防跌倒活动。我们审查了“停止跌倒”活动的规划和实施情况,希望其他机构也能从中受益,并为日益老龄化的人口持续开展预防跌倒活动。
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引用次数: 0
Outcomes of traumatically injured patients after nighttime transfer from the intensive care unit. 夜间从重症监护室转移的创伤性受伤患者的预后。
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-11-26 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001451
Amy Howk, Devin John Clegg, Jacob C Balmer, Natalie G Foster, Justin Gerard, Anthony S Rowe, Brian Daley

Background: Prior studies have associated nighttime transfer of patients from the intensive care unit (ICU) with increased morbidity. This study sought to examine this relationship in traumatically injured patients, as this has not been previously performed.

Methods: A retrospective review of traumatically injured patients admitted to a Level I Trauma Center's ICU from January 2021 to September 2022 was performed. "Day shift" (DS) was defined as 07:00 to 19:00 and "night shift" (NS) as 19:01 to 06:59. The time of transfer completion was based on the time of the patient arrival at the destination unit. The univariate analysis compared patients with completed transfers during DS and NS. Multivariate logistic regression was performed to predict readmission to the ICU.

Results: A total of 1,800 patients were included in the analysis, with 608 patients that had completed transfers during NS, and 1,192 during DS. Both groups were similar, with no significant differences in age, sex, Injury Severity Score (ISS), mechanism of injury, or median total comorbidities. The NS group had a longer median time to transfer completion (10.1 (IQR 5.5-13.6) hours vs 5.1 (IQR 2.9-8.4) hours; p<0.001). A significantly higher proportion of the NS group had a readmission to the ICU (60 (10.0%) vs 86 (7.0%); p=0.03) or a major complication (72 (11.9%) vs 107 (9.0%); p=0.048). When controlling for age, comorbidities, ISS, time to bed assignment and to transfer completed, and ICU length of stay, transfer completion during NS was associated with 1.56 times higher odds of having an ICU readmission (OR 1.56 (95% CI 1.05, 2.33); p=0.03).

Conclusions: Trauma patients transferred from the ICU during NS experienced longer delays, readmission to the ICU, and major complications significantly more often. With increasing hospital bed shortages, patient transfers must be analyzed to minimize worsened outcomes, especially in traumatically injured patients.

Level of evidence: Level III, therapeutic/care management.

背景:先前的研究表明夜间从重症监护病房(ICU)转移患者与发病率增加有关。这项研究试图检查创伤性损伤患者的这种关系,因为这之前没有进行过。方法:回顾性分析2021年1月至2022年9月在某一级创伤中心ICU收治的创伤性损伤患者。“白班”定义为07:00至19:00,“夜班”定义为19:01至06:59。转移完成的时间以患者到达目的单位的时间为基础。单变量分析比较了DS和NS期间完成转移的患者。采用多变量logistic回归预测再入院情况。结果:共有1800名患者被纳入分析,其中608名患者在NS期间完成了转移,1192名患者在DS期间完成了转移。两组相似,在年龄、性别、损伤严重程度评分(ISS)、损伤机制或中位总合并症方面无显著差异。NS组转移完成的中位时间更长(10.1 (IQR 5.5-13.6)小时vs 5.1 (IQR 2.9-8.4)小时;结论:在NS期间从ICU转移的创伤患者经历了更长的延迟、再入院和更频繁的主要并发症。随着医院床位短缺的增加,必须对患者转移进行分析,以尽量减少恶化的结果,特别是在创伤性受伤患者中。证据等级:III级,治疗/护理管理。
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引用次数: 0
Potential new treatment for inferior vena cava injury using extracorporeal membrane oxygenation applying flow diversion effect. 利用体外膜氧合技术的血流分流效应治疗下腔静脉损伤的潜在新疗法。
IF 2.1 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-11-18 eCollection Date: 2024-01-01 DOI: 10.1136/tsaco-2024-001618
Takaaki Maruhashi, Keita Saku, Hideo Maruki, Marina Oi, Yasushi Asari

Background: Retrohepatic inferior vena cava (IVC) injuries remain among the most lethal and serious liver injuries. Gauze packing is currently the first choice for IVC injuries; however, laparotomy itself poses the risk of circulatory collapse. Thus, less invasive treatment strategies are needed.

Methods: In this study, we conducted an animal experiment to replicate and validate successful treatments for an actual case of retrohepatic IVC injury that we had encountered.

Results: A woman in her 80s presented to our hospital due to cardiac arrest caused by a pulmonary artery embolism. Venoarterial extracorporeal membrane oxygenation (ECMO) was introduced, and the patient was resuscitated. After resuscitation, contrast-enhanced CT revealed liver and retrohepatic IVC injuries, possibly caused by chest compressions. Liver injury was treated using transarterial embolization of the left hepatic artery. To treat the retrohepatic IVC injury, ECMO flow was increased to enhance the negative drainage pressure. The extravasation of the contrast medium had resolved in IVC angiography, and we opted for nonoperative management. The patient's hemodynamic status gradually stabilized, and ECMO was withdrawn on day 6. We confirmed these findings in a dog model of retrohepatic IVC injury.

Conclusions: Our findings from the patient and the animal model suggest that the flow diversion effect of ECMO can effectively manage active bleeding from the IVC by inserting a drainage cannula across the injured lesion. We think this procedure represents a novel treatment option for retrohepatic IVC injuries.

背景:肝后下腔静脉(IVC)损伤仍是最致命、最严重的肝损伤之一。目前,纱布填塞是治疗 IVC 损伤的首选方法;然而,开腹手术本身就存在循环衰竭的风险。因此,我们需要创伤更小的治疗策略:在本研究中,我们进行了一项动物实验,以复制和验证我们遇到的一例肝后 IVC 损伤的成功治疗方法:结果:一名 80 多岁的妇女因肺动脉栓塞导致心脏骤停而来到我院。我们引入了静脉体外膜肺氧合(ECMO),并对患者进行了抢救。复苏后,对比增强 CT 显示肝脏和肝后 IVC 损伤,可能是胸外按压造成的。经动脉栓塞左肝动脉治疗了肝损伤。为了治疗肝后 IVC 损伤,增加了 ECMO 流量以提高负引流压。造影剂外渗在 IVC 血管造影中已经消失,我们选择了非手术治疗。患者的血液动力学状态逐渐稳定,ECMO 于第 6 天撤出。我们在狗肝后静脉损伤模型中证实了这些发现:我们在患者和动物模型上的研究结果表明,ECMO 的血流分流作用可通过在损伤病灶处插入引流插管,有效控制 IVC 的活动性出血。我们认为,这种方法是治疗肝后 IVC 损伤的一种新选择。
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引用次数: 0
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Trauma Surgery & Acute Care Open
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