首页 > 最新文献

Tropical Medicine and Health最新文献

英文 中文
Ethnobotanical survey of medicinal and ritual plants utilized by the indigenous communities of Benguet province, Philippines. 菲律宾本格特省土著社区使用的药用植物和祭祀植物的人种植物学调查。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-09-10 DOI: 10.1186/s41182-024-00624-1
Janna R Andalan, Alissa Jane S Mondejar, Nanette Hope N Sumaya, Jaime Q Guihawan, Ma Reina Suzette B Madamba, Carlito Baltazar Tabelin, David Guilingen, Florifern C Paglinawan, Kryzzyl M Maulas, Isidro Arquisal, Arnel B Beltran, Aileen H Orbecido, Michael Angelo Promentilla, Dennis Alonzo, Pamela Flynn Pisda, Alleah Ananayo, Marlon Suelto, Irish Mae Dalona, Vannie Joy Resabal, Robin Armstrong, Anne D Jungblut, Ana Santos, Pablo Brito-Parada, Yves Plancherel, Richard Herrington, Mylah Villacorte-Tabelin

Background: The Sto. Niño site in Benguet province, Philippines was once a mining area that has now been transformed into an agricultural land. In this area, there has been significant integration of the three indigenous people (IPs) Ibaloi, Kankanaeys and Kalanguyas with the Ilocano community. These IPs safeguard biodiversity and traditional knowledge, including medicinal plant use. However, the documentation of these plant species and their medicinal applications has not been systematic, with the resultant loss of knowledge across generations. This study aims to document the medicinal and ritual plants used by the indigenous communities at the site, in order to preserve and disseminate traditional medicinal knowledge that would otherwise be lost.

Methods: Ethnobotanical data were collected in Sto. Niño, Brgy. Ambassador, Municipality of Tublay, Benguet, Philippines, and collected through semi-structured interviews, together with focus group discussions (FGD). A total of 100 residents (39 male and 61 female) were interviewed. Among them, 12 were key interviewees, including community elders and farmers, while the rest were selected through the convenience and snowball technique. Demographic information collected from the interviewees included age, gender, and occupation. Ethnobotanical information collected focused on medicinal plants, including the specific parts of plants used, methods of preparation, modes of treatment, and the types of ailments treated. Ethnobotanical quantitative indices of the relative frequency of citations (RFC) and informant consensus factor (ICF) were calculated to evaluate the plant species that were utilized by the community.

Results: A total of 28 medicinal plants from 20 different families and 6 ritual plants from 5 different families were documented. Asteraceae, Poaceae, and Lamiaceae (10.71%) family are the most mentioned medicinal plant species, followed by Myrtaceae and Euphorbiaceae (7.14%). The most widely used growth form were herbs (46.4%), while leaves (61.5%) were the most utilized plant part, and the preparation of a decoction (62.2%) was the most preferred method of processing and application. The medicinal plants were most commonly utilized for wound-healing, cough and colds, stomachache and kidney trouble, whereas ritual plants were largely used for healing, protection, and funeral ceremonies.

Conclusion: This study marks the first report on the medicinal and ritual plants used by a group of indigenous communities in Sto. Niño, Brgy. Ambassador, Tublay, Benguet Province. The data collected show that plant species belonging to the Asteraceae, Poaceae, and Lamiaceae family were the most mentioned and should be further evaluated by pharmacological analysis to assess their wider use for medicinal treatment.

背景介绍菲律宾本格特省的圣尼诺(Sto. Niño)地区曾经是一个采矿区,现在已经变成了一片农田。在这一地区,伊巴洛伊人(Ibaloi)、坎卡纳伊人(Kankanaeys)和卡兰吉亚斯人(Kalanguyas)这三个土著人与伊洛卡诺人(Ilocano)社区进行了大量融合。这些土著人保护生物多样性和传统知识,包括药用植物的使用。然而,对这些植物物种及其药用用途的记录并不系统,导致知识世代相传。本研究旨在记录原住民社区在该地点使用的药用植物和祭祀植物,以保护和传播传统医药知识,否则这些知识就会失传:在菲律宾本格特省 Tublay 市大使区 Sto.共采访了 100 名居民(39 名男性和 61 名女性)。其中 12 人为关键受访者,包括社区长老和农民,其余受访者则是通过便利和滚雪球技术选出的。从受访者那里收集到的人口信息包括年龄、性别和职业。收集到的人种植物学信息主要集中在药用植物方面,包括植物的具体使用部位、制备方法、治疗方式和治疗疾病的类型。通过计算引用相对频率(RFC)和信息提供者共识因子(ICF)等民族植物学定量指数来评估社区使用的植物物种:结果:共记录了 20 个科 28 种药用植物和 5 个科 6 种祭祀植物。提及最多的药用植物种类是菊科(Asteraceae)、蒲葵科(Poaceae)和苎麻科(Lamiaceae)(10.71%),其次是桃金娘科(Myrtaceae)和大戟科(Euphorbiaceae)(7.14%)。最广泛使用的生长形式是草本植物(46.4%),而叶子(61.5%)是最常用的植物部分,煎煮(62.2%)是最常用的加工和应用方法。药用植物最常用于治疗伤口、咳嗽和感冒、胃痛和肾病,而祭祀植物则主要用于治疗、保护和葬礼仪式:这项研究首次报告了本格特省 Tublay 大使区 Sto.收集到的数据显示,菊科、罂粟科和苎麻科植物是被提及最多的植物物种,应通过药理分析对其进行进一步评估,以确定其在药用治疗方面的广泛用途。
{"title":"Ethnobotanical survey of medicinal and ritual plants utilized by the indigenous communities of Benguet province, Philippines.","authors":"Janna R Andalan, Alissa Jane S Mondejar, Nanette Hope N Sumaya, Jaime Q Guihawan, Ma Reina Suzette B Madamba, Carlito Baltazar Tabelin, David Guilingen, Florifern C Paglinawan, Kryzzyl M Maulas, Isidro Arquisal, Arnel B Beltran, Aileen H Orbecido, Michael Angelo Promentilla, Dennis Alonzo, Pamela Flynn Pisda, Alleah Ananayo, Marlon Suelto, Irish Mae Dalona, Vannie Joy Resabal, Robin Armstrong, Anne D Jungblut, Ana Santos, Pablo Brito-Parada, Yves Plancherel, Richard Herrington, Mylah Villacorte-Tabelin","doi":"10.1186/s41182-024-00624-1","DOIUrl":"https://doi.org/10.1186/s41182-024-00624-1","url":null,"abstract":"<p><strong>Background: </strong>The Sto. Niño site in Benguet province, Philippines was once a mining area that has now been transformed into an agricultural land. In this area, there has been significant integration of the three indigenous people (IPs) Ibaloi, Kankanaeys and Kalanguyas with the Ilocano community. These IPs safeguard biodiversity and traditional knowledge, including medicinal plant use. However, the documentation of these plant species and their medicinal applications has not been systematic, with the resultant loss of knowledge across generations. This study aims to document the medicinal and ritual plants used by the indigenous communities at the site, in order to preserve and disseminate traditional medicinal knowledge that would otherwise be lost.</p><p><strong>Methods: </strong>Ethnobotanical data were collected in Sto. Niño, Brgy. Ambassador, Municipality of Tublay, Benguet, Philippines, and collected through semi-structured interviews, together with focus group discussions (FGD). A total of 100 residents (39 male and 61 female) were interviewed. Among them, 12 were key interviewees, including community elders and farmers, while the rest were selected through the convenience and snowball technique. Demographic information collected from the interviewees included age, gender, and occupation. Ethnobotanical information collected focused on medicinal plants, including the specific parts of plants used, methods of preparation, modes of treatment, and the types of ailments treated. Ethnobotanical quantitative indices of the relative frequency of citations (RFC) and informant consensus factor (ICF) were calculated to evaluate the plant species that were utilized by the community.</p><p><strong>Results: </strong>A total of 28 medicinal plants from 20 different families and 6 ritual plants from 5 different families were documented. Asteraceae, Poaceae, and Lamiaceae (10.71%) family are the most mentioned medicinal plant species, followed by Myrtaceae and Euphorbiaceae (7.14%). The most widely used growth form were herbs (46.4%), while leaves (61.5%) were the most utilized plant part, and the preparation of a decoction (62.2%) was the most preferred method of processing and application. The medicinal plants were most commonly utilized for wound-healing, cough and colds, stomachache and kidney trouble, whereas ritual plants were largely used for healing, protection, and funeral ceremonies.</p><p><strong>Conclusion: </strong>This study marks the first report on the medicinal and ritual plants used by a group of indigenous communities in Sto. Niño, Brgy. Ambassador, Tublay, Benguet Province. The data collected show that plant species belonging to the Asteraceae, Poaceae, and Lamiaceae family were the most mentioned and should be further evaluated by pharmacological analysis to assess their wider use for medicinal treatment.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11385124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental health problems in Somalia after decades of humanitarian crises: a qualitative exploration of perceptions and experiences. 几十年人道主义危机后索马里的心理健康问题:对看法和经历的定性探索。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-09-09 DOI: 10.1186/s41182-024-00618-z
Md Manirul Islam, Abdiwali Ahmed Siyad, Sk Md Mamunur Rahman Malik

Background: Humanitarian crises increase the risk of mental health problems. Somalia has been affected by conflict, insecurity, and economic turmoil for over three decades, as well as climatic shocks. However, 80-90% of Somalis who have mental health problems do not have access to good-quality, and affordable mental health care. To develop an evidence-based, effective, equitable, and humane programme for mental health, we need to have a holistic understanding of mental health problems and care in relation to people's perceptions, experiences, and behaviour related to mental health.

Methods: We undertook a qualitative study to explore Somalis' perceptions and experiences of mental health problems. We conducted three key informant interviews, two in-depth interviews, nine focus group discussions, 12 observations in private and public health facilities and more than 12 informal discussions. We used case vignettes translated into Somali during our discussion. We also studied three cases with experience of mental health problems to understand care-seeking behaviour and the experiences with services available.

Results: Somalia has been moving from a traditional pastoral nomadic lifestyle to a settled one. A strong informal support system exists in the community within clans or family relations. Armed conflict often among clans, natural disasters, and khat use are the three main factors affecting mental health. The prevalence of mental problems is likely greater than is evident. It is perceived that about 95% of people suffering from mental illness remain outside of appropriate care. Few people seek care for mental health problems because they are not aware of it and because it is highly stigmatized and neglected. Those who do seek care usually go to traditional healers because of culture and cost. Resources for mental health care are grossly inadequate with a limited and often poorly trained workforce. At least two levels of barrier to mental health care exist, at the individual/family level (e.g. poor awareness of mental health and stigma) and service provider level (e.g. lack of staff and limited ability to diagnose, treat, or refer persons with mental health problems and stigma). No tool or evidence-based programme is available to address these barriers.

Conclusion: A qualitative data-driven mental health programme that addresses all these issues is needed with more trained mental health professionals. Given the stigma about mental health problems, there is also a need for a tool to raise awareness about mental health and the importance of mental health care among both the public and health workers.

背景:人道主义危机会增加出现心理健康问题的风险。三十多年来,索马里一直受到冲突、不安全和经济动荡以及气候冲击的影响。然而,80%-90% 有心理健康问题的索马里人都无法获得优质且负担得起的心理保健服务。为了制定一个以证据为基础的、有效的、公平的和人性化的心理健康计划,我们需要全面了解心理健康问题,以及与人们对心理健康的看法、经历和行为相关的护理:我们开展了一项定性研究,探讨索马里人对心理健康问题的看法和经历。我们进行了 3 次关键信息提供者访谈、2 次深入访谈、9 次焦点小组讨论、12 次在私营和公共医疗机构的观察以及超过 12 次非正式讨论。在讨论过程中,我们使用了翻译成索马里语的案例小故事。我们还研究了三个有心理健康问题经历的案例,以了解寻求护理的行为和获得服务的经历:索马里正在从传统的游牧生活方式向定居生活方式转变。社区中的氏族或家庭关系中存在着强大的非正式支持系统。经常发生在部族之间的武装冲突、自然灾害和阿拉伯茶的使用是影响心理健康的三个主要因素。精神问题的发生率可能比实际情况要高。据估计,约 95% 的精神疾病患者得不到适当的治疗。很少有人寻求精神健康方面的治疗,因为他们没有意识到这一点,也因为精神疾病被严重鄙视和忽视。由于文化和费用的原因,那些寻求治疗的人通常会去找传统的治疗师。用于心理健康护理的资源严重不足,劳动力有限,而且往往训练有素。心理健康护理至少存在两个层面的障碍,即个人/家庭层面(如对心理健康认识不足和成见)和服务提供者层面(如缺乏工作人员,诊断、治疗或转介有心理健康问题的人的能力有限和成见)。没有任何工具或循证方案可以解决这些障碍:结论:需要有更多训练有素的心理健康专业人员来实施一项以定性数据为导向的心理健康计划,以解决所有这些问题。鉴于人们对心理健康问题的成见,还需要一种工具来提高公众和卫生工作者对心理健康和心理保健重要性的认识。
{"title":"Mental health problems in Somalia after decades of humanitarian crises: a qualitative exploration of perceptions and experiences.","authors":"Md Manirul Islam, Abdiwali Ahmed Siyad, Sk Md Mamunur Rahman Malik","doi":"10.1186/s41182-024-00618-z","DOIUrl":"https://doi.org/10.1186/s41182-024-00618-z","url":null,"abstract":"<p><strong>Background: </strong>Humanitarian crises increase the risk of mental health problems. Somalia has been affected by conflict, insecurity, and economic turmoil for over three decades, as well as climatic shocks. However, 80-90% of Somalis who have mental health problems do not have access to good-quality, and affordable mental health care. To develop an evidence-based, effective, equitable, and humane programme for mental health, we need to have a holistic understanding of mental health problems and care in relation to people's perceptions, experiences, and behaviour related to mental health.</p><p><strong>Methods: </strong>We undertook a qualitative study to explore Somalis' perceptions and experiences of mental health problems. We conducted three key informant interviews, two in-depth interviews, nine focus group discussions, 12 observations in private and public health facilities and more than 12 informal discussions. We used case vignettes translated into Somali during our discussion. We also studied three cases with experience of mental health problems to understand care-seeking behaviour and the experiences with services available.</p><p><strong>Results: </strong>Somalia has been moving from a traditional pastoral nomadic lifestyle to a settled one. A strong informal support system exists in the community within clans or family relations. Armed conflict often among clans, natural disasters, and khat use are the three main factors affecting mental health. The prevalence of mental problems is likely greater than is evident. It is perceived that about 95% of people suffering from mental illness remain outside of appropriate care. Few people seek care for mental health problems because they are not aware of it and because it is highly stigmatized and neglected. Those who do seek care usually go to traditional healers because of culture and cost. Resources for mental health care are grossly inadequate with a limited and often poorly trained workforce. At least two levels of barrier to mental health care exist, at the individual/family level (e.g. poor awareness of mental health and stigma) and service provider level (e.g. lack of staff and limited ability to diagnose, treat, or refer persons with mental health problems and stigma). No tool or evidence-based programme is available to address these barriers.</p><p><strong>Conclusion: </strong>A qualitative data-driven mental health programme that addresses all these issues is needed with more trained mental health professionals. Given the stigma about mental health problems, there is also a need for a tool to raise awareness about mental health and the importance of mental health care among both the public and health workers.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11382377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A serological survey of COVID-19 among predominantly aboriginal residents of a tourist island in southern Thailand. 对泰国南部一个旅游岛屿上以土著居民为主的人群进行 COVID-19 血清学调查。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-09-04 DOI: 10.1186/s41182-024-00617-0
Supakorn Sripaew, Kameelah Yasharad, Dzerlina S Rahari, Weiyan Feng, Zhenzhu Qian, Huynh Ngoc Thanh, Pei Li, Agus Fitriangga, Satiti Palupi Purwanto, Aye Nyein Phyu, Fangming Xianyu, Sombat Phadungvitvatthana, Wit Wichaidit, Ponlagrit Kumwichar, Virasakdi Chongsuvivatwong

Background: The current survey describes the seroprevalence, history of coronavirus disease 2019 (COVID-19), and vaccination status among predominantly aboriginal residents on a tourist island in southern Thailand. This information can be translated into COVID-19 vaccination and control plans for this population.

Methods: We implemented questionnaire interviews and collected blood samples from 249 residents of Lipe Island, Satun Province, in January 2022. We measured the anti-nucleocapsid protein and anti-spike (anti-S) receptor-binding protein levels of immunoglobulin (Ig) M and IgG. The differences in antibody levels among participants with different histories of vaccination and infection were analyzed using one-way analysis of variance with multiple comparisons.

Results: During the 2-year pandemic period, no island residents with COVID-19 required hospitalization despite the high prevalence of hypertension (33.3%) and diabetes mellitus (21.7%). Approximately 18.8% of the participants reported a history of COVID-19 diagnosis. In total, 95.1% of the participants had a history of complete vaccination, of which 93.5% were seropositive. The anti-S IgG geometric means (geometric standard deviation) were 3945.8 (2.0), 829.8 (9.7) AU/mL, 789.9 (5.3) AU/mL, and 22.7 (7.1) AU/mL, respectively, in participants with a history of both COVID-19 diagnosis and complete vaccination (group 1), incomplete vaccination and subsequent COVID-19 diagnosis (group 2), complete vaccination but no previous infection (group 3), or neither previous COVID-19 and complete vaccination (group 4). Significant pairwise differences in anti-S IgG levels were found between certain groups (1 vs 3, 1 vs 4, 2 vs 4, and 3 vs 4).

Conclusions: The high coverage of vaccination, high levels of population antibody titers, variable antibody levels among completely vaccinated non-infected residents, and high prevalence of non-communicable diseases (NCDs) suggested that the local health systems could control the pandemic. However, continuing surveillance, booster vaccinations, and NCD prevention programs were still required.

背景:本次调查描述了泰国南部一个旅游岛屿上以原住民为主的居民的血清流行率、冠状病毒病 2019(COVID-19)病史和疫苗接种情况。这些信息可转化为针对该人群的 COVID-19 疫苗接种和控制计划:我们于 2022 年 1 月对沙吞府利佩岛的 249 名居民进行了问卷调查并采集了血样。我们测量了免疫球蛋白 (Ig) M 和 IgG 中抗核壳蛋白和抗尖峰受体结合蛋白的水平。我们采用单因素方差分析和多重比较的方法分析了不同疫苗接种史和感染史的参与者之间抗体水平的差异:结果:在为期两年的大流行期间,尽管高血压(33.3%)和糖尿病(21.7%)的发病率很高,但岛上居民中没有人因感染 COVID-19 而需要住院治疗。约 18.8% 的参与者报告了 COVID-19 诊断史。95.1%的参与者有完整的疫苗接种史,其中93.5%血清呈阳性。抗 S IgG 的几何平均数(几何标准偏差)分别为 3945.8 (2.0)、829.8 (9.7) AU/mL、789.9 (5.3) AU/mL 和 22.7 (7. 1) AU/mL。在既有 COVID-19 诊断史又完全接种过疫苗(第 1 组)、未完全接种疫苗且随后诊断出 COVID-19 (第 2 组)、完全接种疫苗但既往未感染过(第 3 组)或既往未感染过 COVID-19 也未完全接种过疫苗(第 4 组)的参与者中,抗-S 免疫球蛋白含量分别为 829.8 (9.7) AU/mL、789.9 (5.3) AU/mL 和 22.7 (7.1) AU/mL。某些组别(1 vs 3、1 vs 4、2 vs 4 和 3 vs 4)之间的抗 S IgG 水平存在明显的配对差异:疫苗接种的高覆盖率、高水平的人群抗体滴度、完全接种疫苗的非感染居民的抗体水平参差不齐以及非传染性疾病 (NCD) 的高发病率表明,当地卫生系统能够控制大流行。但是,仍然需要继续监测、加强接种疫苗和非传染性疾病预防计划。
{"title":"A serological survey of COVID-19 among predominantly aboriginal residents of a tourist island in southern Thailand.","authors":"Supakorn Sripaew, Kameelah Yasharad, Dzerlina S Rahari, Weiyan Feng, Zhenzhu Qian, Huynh Ngoc Thanh, Pei Li, Agus Fitriangga, Satiti Palupi Purwanto, Aye Nyein Phyu, Fangming Xianyu, Sombat Phadungvitvatthana, Wit Wichaidit, Ponlagrit Kumwichar, Virasakdi Chongsuvivatwong","doi":"10.1186/s41182-024-00617-0","DOIUrl":"10.1186/s41182-024-00617-0","url":null,"abstract":"<p><strong>Background: </strong>The current survey describes the seroprevalence, history of coronavirus disease 2019 (COVID-19), and vaccination status among predominantly aboriginal residents on a tourist island in southern Thailand. This information can be translated into COVID-19 vaccination and control plans for this population.</p><p><strong>Methods: </strong>We implemented questionnaire interviews and collected blood samples from 249 residents of Lipe Island, Satun Province, in January 2022. We measured the anti-nucleocapsid protein and anti-spike (anti-S) receptor-binding protein levels of immunoglobulin (Ig) M and IgG. The differences in antibody levels among participants with different histories of vaccination and infection were analyzed using one-way analysis of variance with multiple comparisons.</p><p><strong>Results: </strong>During the 2-year pandemic period, no island residents with COVID-19 required hospitalization despite the high prevalence of hypertension (33.3%) and diabetes mellitus (21.7%). Approximately 18.8% of the participants reported a history of COVID-19 diagnosis. In total, 95.1% of the participants had a history of complete vaccination, of which 93.5% were seropositive. The anti-S IgG geometric means (geometric standard deviation) were 3945.8 (2.0), 829.8 (9.7) AU/mL, 789.9 (5.3) AU/mL, and 22.7 (7.1) AU/mL, respectively, in participants with a history of both COVID-19 diagnosis and complete vaccination (group 1), incomplete vaccination and subsequent COVID-19 diagnosis (group 2), complete vaccination but no previous infection (group 3), or neither previous COVID-19 and complete vaccination (group 4). Significant pairwise differences in anti-S IgG levels were found between certain groups (1 vs 3, 1 vs 4, 2 vs 4, and 3 vs 4).</p><p><strong>Conclusions: </strong>The high coverage of vaccination, high levels of population antibody titers, variable antibody levels among completely vaccinated non-infected residents, and high prevalence of non-communicable diseases (NCDs) suggested that the local health systems could control the pandemic. However, continuing surveillance, booster vaccinations, and NCD prevention programs were still required.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of integrated WASH and maternal and child health interventions on diarrhea disease prevalence in a resource-constrained setting in Kenya. 在肯尼亚资源有限的环境中,讲卫生运动和妇幼保健综合干预措施对腹泻疾病流行的影响。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-08-30 DOI: 10.1186/s41182-024-00616-1
Betty Muriithi, Ernest Apondi Wandera, Rie Takeuchi, Felix Mutunga, Cyrus Kathiiko, Mary Wachira, Joseph Tinkoi, Mirasine Meiguran, Pius Akumu, Valeria Ndege, Ryoichiro Mochizuki, Satoshi Kaneko, Kouichi Morita, Collins Ouma, Yoshio Ichinose

Background: Water, sanitation and hygiene (WASH) and child health interventions are proven simple and cost-effective strategies for preventing diarrhea and minimizing excess mortality. Individually, they are able to prevent diarrhea though sub-optimally, and their effectiveness when combined may be higher. This study examined the effect of integrated WASH and maternal and child health (MCH) interventions on prevalence of diarrhea, in a resource-limited setting in Kenya.

Methods: A controlled intervention was implemented in Narok County. The interventions included WASH interventions integrated with promotion of MCH. A structured questionnaire was used to collect data on targeted indicators before and after the interventions. Data were analyzed using descriptive statistics and Chi-square to establish the impact of the interventions.

Results: A total of 431and 424 households and 491 and 487 households in intervention and control sites, respectively, participated in the baseline and endline surveys. Following implementation of the interventions, prevalence of diarrhea decreased by 69.1% (95% CI: 49.6-87.1%) and 58.6% (95% CI: 26.6-82.4%) in the intervention and control site, respectively. Treatment of drinking water and animal husbandry practices were significantly associated with diarrhea post-interventions.

Conclusions: Integrating WASH interventions with other diarrhea control strategies and contextualizing them to meet site-specific needs may effectively prevent diarrhea.

背景:事实证明,水、环境卫生和个人卫生(WASH)以及儿童健康干预措施是预防腹泻和最大限度降低超额死亡率的简单而经济有效的策略。单独使用这些干预措施可以预防腹泻,但效果并不理想,如果将它们结合起来,效果可能会更好。本研究考察了在肯尼亚资源有限的环境中,综合讲卫生运动和妇幼保健(MCH)干预措施对腹泻发病率的影响:方法:在纳罗克县实施了一项对照干预措施。方法:在纳罗克县实施了一项对照干预措施,干预措施包括讲卫生运动干预措施与促进妇幼保健相结合。采用结构化问卷收集干预前后的目标指标数据。使用描述性统计和卡方对数据进行分析,以确定干预措施的影响:共有 431 和 424 个家庭参加了基线和终点调查,干预点和对照点分别有 491 和 487 个家庭参加。干预措施实施后,干预点和对照点的腹泻发病率分别下降了 69.1%(95% CI:49.6-87.1%)和 58.6%(95% CI:26.6-82.4%)。饮用水处理和畜牧业做法与干预后的腹泻显著相关:结论:将饮水、环卫和讲卫生运动干预措施与其他腹泻控制策略相结合,并根据具体地点的需求加以调整,可有效预防腹泻。
{"title":"Impact of integrated WASH and maternal and child health interventions on diarrhea disease prevalence in a resource-constrained setting in Kenya.","authors":"Betty Muriithi, Ernest Apondi Wandera, Rie Takeuchi, Felix Mutunga, Cyrus Kathiiko, Mary Wachira, Joseph Tinkoi, Mirasine Meiguran, Pius Akumu, Valeria Ndege, Ryoichiro Mochizuki, Satoshi Kaneko, Kouichi Morita, Collins Ouma, Yoshio Ichinose","doi":"10.1186/s41182-024-00616-1","DOIUrl":"10.1186/s41182-024-00616-1","url":null,"abstract":"<p><strong>Background: </strong>Water, sanitation and hygiene (WASH) and child health interventions are proven simple and cost-effective strategies for preventing diarrhea and minimizing excess mortality. Individually, they are able to prevent diarrhea though sub-optimally, and their effectiveness when combined may be higher. This study examined the effect of integrated WASH and maternal and child health (MCH) interventions on prevalence of diarrhea, in a resource-limited setting in Kenya.</p><p><strong>Methods: </strong>A controlled intervention was implemented in Narok County. The interventions included WASH interventions integrated with promotion of MCH. A structured questionnaire was used to collect data on targeted indicators before and after the interventions. Data were analyzed using descriptive statistics and Chi-square to establish the impact of the interventions.</p><p><strong>Results: </strong>A total of 431and 424 households and 491 and 487 households in intervention and control sites, respectively, participated in the baseline and endline surveys. Following implementation of the interventions, prevalence of diarrhea decreased by 69.1% (95% CI: 49.6-87.1%) and 58.6% (95% CI: 26.6-82.4%) in the intervention and control site, respectively. Treatment of drinking water and animal husbandry practices were significantly associated with diarrhea post-interventions.</p><p><strong>Conclusions: </strong>Integrating WASH interventions with other diarrhea control strategies and contextualizing them to meet site-specific needs may effectively prevent diarrhea.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11363663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Actinomyces funkei bacteraemia and infected pulmonary cavities in an intravenous drug user: a case report. 一名静脉注射吸毒者的放线菌菌血症和肺腔感染:病例报告。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-08-26 DOI: 10.1186/s41182-024-00610-7
Tanaraj Perinpanathan, Katherine Beckett, Chris Smith

Background: Actinomyces spp. are most commonly found in human commensal flora; however, they have also been shown to cause suppurative infections. We present a case of a rare Actinomyces funkei bacteraemia from an infected deep vein thrombosis in a patient who went on to develop pulmonary cavities secondary to septic emboli. Infected thrombi and septic emboli have been associated with other Actinomyces spp. in the literature, often posing a diagnostic challenge and, in some cases, causing drastic clinical deterioration in patients. The literature regarding Actinomyces funkei is scarce and to our knowledge there are no reports of a relationship between this Actinomyces subspecies and infected thrombi or septic emboli.

Case presentation: The patient was a 39-year-old known intravenous drug user who presented with a groin injecting site sinus and systemic symptoms. The bacteria was first observed by gram staining of a blood culture sample after 48 h of incubation and the species was identified using matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) as Actinomyces funkei. Sputum cytology/histology with cell block revealed a branching gram-positive species suspicious of slow growing bacteria or fungus. CT imaging of his lower limb and chest revealed an extensive DVT with inflammatory changes and pulmonary cavities respectively. The patient was treated with Ceftriaxone before being discharged with a 6-month course of Linezolid. He made a good recovery with reduction in size of the cavitating lung lesions on follow-up imaging.

Conclusions: This case report presents a difficult-to-diagnose bacterial infection in an intravenous drug user, complicated by bacteraemia and secondary septic emboli. Relatively little is known about Actinomyces funkei, and therefore this report aims to increase clinician awareness of diagnosis, management, and complications.

背景:放线菌属最常见于人类共生菌群,但也被证明可引起化脓性感染。我们介绍了一例罕见的放线菌菌血症病例,患者因感染深静脉血栓而继发肺腔化脓性栓塞。在文献中,感染性血栓和化脓性栓子与其他放线菌属有关,往往给诊断带来困难,在某些情况下还会导致患者临床症状急剧恶化。有关放线菌的文献很少,据我们所知,还没有关于这种放线菌亚种与感染性血栓或化脓性栓子之间关系的报道:患者是一名 39 岁的已知静脉注射吸毒者,出现腹股沟注射部位窦道和全身症状。培养 48 小时后,通过对血液培养样本进行革兰氏染色首次观察到该细菌,并使用基质辅助激光解吸电离飞行时间(MALDI-TOF)鉴定出其为放线菌。痰细胞学/组织学检查和细胞阻断发现了一种革兰氏阳性分支菌,怀疑是生长缓慢的细菌或真菌。下肢和胸部的 CT 成像显示,深静脉血栓广泛存在,并分别伴有炎症变化和肺空洞。患者接受了头孢曲松治疗,出院前服用了为期 6 个月的利奈唑胺。患者恢复良好,随访造影显示肺部空洞病灶缩小:本病例报告了一名静脉注射吸毒者因细菌感染而导致的难以诊断的并发菌血症和继发性化脓性栓塞。人们对放线菌的了解相对较少,因此本报告旨在提高临床医生对诊断、处理和并发症的认识。
{"title":"Actinomyces funkei bacteraemia and infected pulmonary cavities in an intravenous drug user: a case report.","authors":"Tanaraj Perinpanathan, Katherine Beckett, Chris Smith","doi":"10.1186/s41182-024-00610-7","DOIUrl":"10.1186/s41182-024-00610-7","url":null,"abstract":"<p><strong>Background: </strong>Actinomyces spp. are most commonly found in human commensal flora; however, they have also been shown to cause suppurative infections. We present a case of a rare Actinomyces funkei bacteraemia from an infected deep vein thrombosis in a patient who went on to develop pulmonary cavities secondary to septic emboli. Infected thrombi and septic emboli have been associated with other Actinomyces spp. in the literature, often posing a diagnostic challenge and, in some cases, causing drastic clinical deterioration in patients. The literature regarding Actinomyces funkei is scarce and to our knowledge there are no reports of a relationship between this Actinomyces subspecies and infected thrombi or septic emboli.</p><p><strong>Case presentation: </strong>The patient was a 39-year-old known intravenous drug user who presented with a groin injecting site sinus and systemic symptoms. The bacteria was first observed by gram staining of a blood culture sample after 48 h of incubation and the species was identified using matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) as Actinomyces funkei. Sputum cytology/histology with cell block revealed a branching gram-positive species suspicious of slow growing bacteria or fungus. CT imaging of his lower limb and chest revealed an extensive DVT with inflammatory changes and pulmonary cavities respectively. The patient was treated with Ceftriaxone before being discharged with a 6-month course of Linezolid. He made a good recovery with reduction in size of the cavitating lung lesions on follow-up imaging.</p><p><strong>Conclusions: </strong>This case report presents a difficult-to-diagnose bacterial infection in an intravenous drug user, complicated by bacteraemia and secondary septic emboli. Relatively little is known about Actinomyces funkei, and therefore this report aims to increase clinician awareness of diagnosis, management, and complications.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142073883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and associated factors of TB and HIV coinfections among adult inmates with presumptive pulmonary TB in a Kenyan prison. 肯尼亚一所监狱中患有肺结核推定病症的成年囚犯中结核病和艾滋病毒合并感染的流行率和相关因素。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-08-16 DOI: 10.1186/s41182-024-00623-2
Suleiman Athuman Mwatenga, Ali A Musa, Margaret W Muturi, Abednego Moki Musyoki

Background: Tuberculosis (TB) is more than ten times higher in prisons compared to the general population, and HIV-infected persons are at increased risk of developing active TB and death. In the World Health Organization (WHO) African region, however, where the TB and HIV coinfections are highest, and prisons rarely factored in national disease surveillance, epidemiological data to inform TB control interventions in correctional facilities is limited. In this study, we assessed the prevalence of TB and HIV coinfections, as well as the factors associated with coinfections in our study setting.

Methods: This was a prospective cross-sectional study among 157 adult (≥ 18 years) prisoners presenting with symptoms of pulmonary TB at Shimo La Tewa Prison, Kenya, between January and June 2023. The study excluded those with a history of anti-TB drugs use or on treatment follow-up and collected demographic and clinical characteristics data using a questionnaire. Sputum samples were collected and processed immediately using Xpert® MTB/RIF assay or stored at 4 °C for three (3) days in case of delay.

Results: The overall prevalence of TB among inmates with presumptive pulmonary TB was 10.2%, 95% CI 6.37-16.91% (16/157), HIV 19.1%, 95% CI 13.73-25.97% (30/157). All the TB cases were positive for HIV (16/16, 100%), translating to TB/HIV coinfection of 10.2%, 95% CI 6.37-16.91% (16/157), and there was no rifampicin resistance. TB and HIV coinfection cases were found among underweight (100%, 16/16) prisoners. The independent factors associated with TB and HIV coinfections were education level (adjusted OR = 0.17, p = 0.007), smoking history (adjusted OR = 3.01, p = 0.009) and illegal drug use history (adjusted OR = 4.55, p = 0.044).

Conclusion: We report a high prevalence of pulmonary TB and HIV coinfections among adult inmates with presumptive pulmonary TB in Kenya, with education level, smoking status, and illegal drug use as the independent factors associated with the coinfection. The authority should take measures to protect HIV-positive prisoners from TB, focusing on education, nutrition, smoking, and illegal drug use.

背景:监狱中结核病(TB)的发病率是普通人群的十倍以上,而艾滋病毒感染者罹患活动性结核病和死亡的风险更高。然而,在世界卫生组织(WHO)非洲地区,结核病和艾滋病病毒的合并感染率最高,而且监狱很少被纳入国家疾病监测范围,因此为惩教机构结核病控制干预提供信息的流行病学数据非常有限。在这项研究中,我们评估了结核病和艾滋病病毒双重感染的流行情况,以及在我们的研究环境中与双重感染相关的因素:这是一项前瞻性横断面研究,研究对象是 2023 年 1 月至 6 月期间在肯尼亚 Shimo La Tewa 监狱出现肺结核症状的 157 名成年(≥ 18 岁)囚犯。研究排除了有抗结核药物使用史或治疗随访史的囚犯,并通过问卷调查收集了人口统计学和临床特征数据。痰液样本收集后立即使用 Xpert® MTB/RIF 检测法进行处理,如需延迟处理,则在 4 °C 下保存三(3)天:结果:在推测患有肺结核的囚犯中,结核病的总发病率为 10.2%,95% CI 为 6.37-16.91%(16/157),艾滋病毒感染率为 19.1%,95% CI 为 13.73-25.97%(30/157)。所有肺结核病例的艾滋病毒检测结果均呈阳性(16/16,100%),因此肺结核/艾滋病毒合并感染率为 10.2%,95% CI 为 6.37-16.91%(16/157),且无利福平耐药性。体重不足的囚犯(16/16,100%)中发现了结核病和艾滋病毒合并感染病例。与肺结核和艾滋病病毒双重感染相关的独立因素是受教育程度(调整后 OR = 0.17,p = 0.007)、吸烟史(调整后 OR = 3.01,p = 0.009)和非法吸毒史(调整后 OR = 4.55,p = 0.044):我们报告了肯尼亚推定肺结核成年囚犯中肺结核和艾滋病毒合并感染的高流行率,教育水平、吸烟状况和非法使用毒品是与合并感染相关的独立因素。当局应采取措施保护艾滋病毒呈阳性的囚犯免受肺结核感染,重点关注教育、营养、吸烟和非法使用毒品等问题。
{"title":"Prevalence and associated factors of TB and HIV coinfections among adult inmates with presumptive pulmonary TB in a Kenyan prison.","authors":"Suleiman Athuman Mwatenga, Ali A Musa, Margaret W Muturi, Abednego Moki Musyoki","doi":"10.1186/s41182-024-00623-2","DOIUrl":"10.1186/s41182-024-00623-2","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) is more than ten times higher in prisons compared to the general population, and HIV-infected persons are at increased risk of developing active TB and death. In the World Health Organization (WHO) African region, however, where the TB and HIV coinfections are highest, and prisons rarely factored in national disease surveillance, epidemiological data to inform TB control interventions in correctional facilities is limited. In this study, we assessed the prevalence of TB and HIV coinfections, as well as the factors associated with coinfections in our study setting.</p><p><strong>Methods: </strong>This was a prospective cross-sectional study among 157 adult (≥ 18 years) prisoners presenting with symptoms of pulmonary TB at Shimo La Tewa Prison, Kenya, between January and June 2023. The study excluded those with a history of anti-TB drugs use or on treatment follow-up and collected demographic and clinical characteristics data using a questionnaire. Sputum samples were collected and processed immediately using Xpert® MTB/RIF assay or stored at 4 °C for three (3) days in case of delay.</p><p><strong>Results: </strong>The overall prevalence of TB among inmates with presumptive pulmonary TB was 10.2%, 95% CI 6.37-16.91% (16/157), HIV 19.1%, 95% CI 13.73-25.97% (30/157). All the TB cases were positive for HIV (16/16, 100%), translating to TB/HIV coinfection of 10.2%, 95% CI 6.37-16.91% (16/157), and there was no rifampicin resistance. TB and HIV coinfection cases were found among underweight (100%, 16/16) prisoners. The independent factors associated with TB and HIV coinfections were education level (adjusted OR = 0.17, p = 0.007), smoking history (adjusted OR = 3.01, p = 0.009) and illegal drug use history (adjusted OR = 4.55, p = 0.044).</p><p><strong>Conclusion: </strong>We report a high prevalence of pulmonary TB and HIV coinfections among adult inmates with presumptive pulmonary TB in Kenya, with education level, smoking status, and illegal drug use as the independent factors associated with the coinfection. The authority should take measures to protect HIV-positive prisoners from TB, focusing on education, nutrition, smoking, and illegal drug use.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11328499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with the uptake of COVID-19 vaccination, testing and medical care among Myanmar migrants in Japan: a cross-sectional study. 在日本的缅甸移民中接受 COVID-19 疫苗接种、检测和医疗护理的相关因素:一项横断面研究。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-08-06 DOI: 10.1186/s41182-024-00621-4
Moe Moe Thandar, Azusa Iwamoto, Haru Angelique Hoshino, Kyoko Sudo, Mihoko Fujii, Miwa Kanda, Saki Ikeda, Masami Fujita

Background: Migrants are individuals who move to a different country from their usual place of residence. Japan's migrant population, particularly technical interns and students, has been growing. Even before the pandemic, previous studies have highlighted difficulties faced by migrants in utilizing healthcare services. This study examined the uptake of COVID-19 vaccination, testing, and medical care among Myanmar migrants in Japan; identified the factors associated with this uptake; and described the difficulties encountered when utilizing these services.

Methods: A cross-sectional study was conducted between March and April 2023 targeting Myanmar migrants over 18 years residing in Japan for more than 6 months. An online self-administered questionnaire in Myanmar language covered socioeconomic characteristics; history of COVID-19 vaccination, testing, and medical care; and difficulties encountered while utilizing these services with multiple-choice questions. Multivariate logistic regression analysis was performed separately to identify the factors associated with the uptake of COVID-19 vaccination, testing, and medical care.

Results: Among the 207 participants, 52% (n = 108) were under 30 years, 30% (n = 62) were male, and 31% (n = 65) were low-skilled workers (technical interns and students). Overall, 91% (n = 189) had received the COVID-19 vaccination, 76% (n = 157) had been tested for COVID-19, and 43% (n = 68) tested positive. However, only 77% (n = 52) of COVID-19 patients sought medical care. Participants under 30 years of age were less likely to receive the COVID-19 vaccine compared to those aged 30 and older (adjusted odds ratio [aOR] 0.10, 95% confidence interval [CI] 0.01-0.88, p = 0.038). Low-skilled workers were less likely to seek medical care compared to those holding other categories of residential status (aOR 0.12, 95% CI 0.02-0.79, p = 0.027). Among service users, 5% faced difficulties with COVID-19 vaccination, 10% with testing, and 17% with receiving medical care. Long waiting times and complex reservation processes were the main difficulties encountered.

Conclusions: The uptake of COVID-19 vaccination, testing, and medical care in this sample was reasonably good. However, individuals under 30 years of age showed lower uptake of vaccination, while low-skilled workers had lower uptake of medical care. Strengthening education and support for young migrants and low-skilled workers regarding COVID-19 and other infectious diseases is essential, especially in workplaces and educational institutions.

背景:移民是指从常住地迁移到不同国家的人。日本的移民人口,尤其是技术实习生和学生,一直在不断增长。即使在流感大流行之前,以往的研究也曾强调过移民在利用医疗保健服务方面所面临的困难。本研究调查了在日本的缅甸移民对 COVID-19 疫苗接种、检测和医疗服务的接受情况,确定了与接受情况相关的因素,并描述了在利用这些服务时遇到的困难:2023 年 3 月至 4 月期间进行了一项横断面研究,研究对象是在日本居住 6 个月以上、年满 18 岁的缅甸移民。在线缅语自填问卷涵盖了社会经济特征、COVID-19 疫苗接种史、检测史和医疗史,以及在利用这些服务时遇到的困难等多项选择题。我们分别进行了多变量逻辑回归分析,以确定与接受 COVID-19 疫苗接种、检测和医疗服务相关的因素:在 207 名参与者中,52%(108 人)在 30 岁以下,30%(62 人)为男性,31%(65 人)为低技能工人(技术实习生和学生)。总体而言,91%(n = 189)的人接种过 COVID-19 疫苗,76%(n = 157)的人接受过 COVID-19 检测,43%(n = 68)的人检测结果呈阳性。然而,只有77%(n = 52)的COVID-19患者就医。与 30 岁及以上的参与者相比,30 岁以下的参与者接种 COVID-19 疫苗的可能性较低(调整赔率比 [aOR] 0.10,95% 置信区间 [CI] 0.01-0.88,p = 0.038)。与其他居住身份类别的人相比,低技术工人就医的可能性较低(aOR 0.12,95% CI 0.02-0.79,p = 0.027)。在服务使用者中,5%的人在接种COVID-19疫苗时遇到困难,10%的人在检测时遇到困难,17%的人在接受医疗护理时遇到困难。等待时间长和预约程序复杂是遇到的主要困难:结论:在此次抽样调查中,COVID-19 疫苗接种、检测和医疗服务的覆盖率相当不错。然而,30 岁以下人群的疫苗接种率较低,而低技能工人的医疗护理率较低。加强对年轻移民和低技能工人有关 COVID-19 和其他传染病的教育和支持至关重要,尤其是在工作场所和教育机构。
{"title":"Factors associated with the uptake of COVID-19 vaccination, testing and medical care among Myanmar migrants in Japan: a cross-sectional study.","authors":"Moe Moe Thandar, Azusa Iwamoto, Haru Angelique Hoshino, Kyoko Sudo, Mihoko Fujii, Miwa Kanda, Saki Ikeda, Masami Fujita","doi":"10.1186/s41182-024-00621-4","DOIUrl":"10.1186/s41182-024-00621-4","url":null,"abstract":"<p><strong>Background: </strong>Migrants are individuals who move to a different country from their usual place of residence. Japan's migrant population, particularly technical interns and students, has been growing. Even before the pandemic, previous studies have highlighted difficulties faced by migrants in utilizing healthcare services. This study examined the uptake of COVID-19 vaccination, testing, and medical care among Myanmar migrants in Japan; identified the factors associated with this uptake; and described the difficulties encountered when utilizing these services.</p><p><strong>Methods: </strong>A cross-sectional study was conducted between March and April 2023 targeting Myanmar migrants over 18 years residing in Japan for more than 6 months. An online self-administered questionnaire in Myanmar language covered socioeconomic characteristics; history of COVID-19 vaccination, testing, and medical care; and difficulties encountered while utilizing these services with multiple-choice questions. Multivariate logistic regression analysis was performed separately to identify the factors associated with the uptake of COVID-19 vaccination, testing, and medical care.</p><p><strong>Results: </strong>Among the 207 participants, 52% (n = 108) were under 30 years, 30% (n = 62) were male, and 31% (n = 65) were low-skilled workers (technical interns and students). Overall, 91% (n = 189) had received the COVID-19 vaccination, 76% (n = 157) had been tested for COVID-19, and 43% (n = 68) tested positive. However, only 77% (n = 52) of COVID-19 patients sought medical care. Participants under 30 years of age were less likely to receive the COVID-19 vaccine compared to those aged 30 and older (adjusted odds ratio [aOR] 0.10, 95% confidence interval [CI] 0.01-0.88, p = 0.038). Low-skilled workers were less likely to seek medical care compared to those holding other categories of residential status (aOR 0.12, 95% CI 0.02-0.79, p = 0.027). Among service users, 5% faced difficulties with COVID-19 vaccination, 10% with testing, and 17% with receiving medical care. Long waiting times and complex reservation processes were the main difficulties encountered.</p><p><strong>Conclusions: </strong>The uptake of COVID-19 vaccination, testing, and medical care in this sample was reasonably good. However, individuals under 30 years of age showed lower uptake of vaccination, while low-skilled workers had lower uptake of medical care. Strengthening education and support for young migrants and low-skilled workers regarding COVID-19 and other infectious diseases is essential, especially in workplaces and educational institutions.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-random distribution of Plasmodium Species infections and associated clinical features in children in the lake Victoria region, Kenya, 2012-2018. 2012-2018年肯尼亚维多利亚湖地区儿童疟原虫感染的非随机分布及相关临床特征。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-08-05 DOI: 10.1186/s41182-024-00622-3
Protus Omondi, Brian Musyoka, Takatsugu Okai, James Kongere, Wataru Kagaya, Chim W Chan, Mtakai Ngara, Bernard N Kanoi, Yasutoshi Kido, Jesse Gitaka, Akira Kaneko

Background: While Plasmodium falciparum (Pf) stands out as the most lethal malaria parasite species in humans, the impact of other species should not be dismissed. Moreover, there is a notable lack of understanding of mixed-species infections and their clinical implications.

Methods: We conducted eight school-based cross-sectional malariometric surveys in the Lake Victoria region of western Kenya between January-February 2012 and September-October 2018. In each survey, a minimum of 100 children aged 3 to 15 years were randomly chosen from a school in Ungoye village on the mainland and as well as from each school selected in every catchment area on Mfangano island. Plasmodium infection was determined by microscopy and nested polymerase chain reaction (PCR). The multiple-kind lottery (MKL) model calculated the expected distribution of Plasmodium infections in the population and compared it to observed values using a chi-squared test (χ2).

Results: The Plasmodium prevalence was 25.9% (2521/9724) by microscopy and 51.1% (4969/9724) by PCR. Among all infections detected by PCR, Pf, P. malariae (Pm), and P. ovale (Po) mono-infections were 58.6%, 3.1%, and 1.8%, respectively. Pf/Pm, Pf/Po, Pm/Po, and Pf/Pm/Po co-infections were 23.5%, 4.3%, 0.1%, and 8.6%, respectively. MKL modelling revealed non-random distributions, with frequencies of Pf/Pm and Pf/Pm/Po co-infections being significantly higher than expected (χ2 = 3385.60, p < 0.001). Pf co-infections with Pm and Po were associated with a decreased risk of fever (aOR 0.64, 95% CI 0.46-0.83; p = 0.01) and increased risks of splenomegaly (aOR 12.79, 95% CI 9.69-16.9; p < 0.001) and anaemia (aOR 2.57, 95% CI 2.09-3.15; p < 0.001), compared to single-species infections.

Conclusion: This study sheds light on the potential interaction between Pf and Pm and/or Po. Given the clinical significance of mixed-species infections, improved diagnostics, and case management of Pm and Po are urgently needed.

背景:虽然恶性疟原虫(Pf)是人类最致命的疟疾寄生虫,但也不应忽视其他种类寄生虫的影响。此外,人们对混合疟原虫感染及其临床影响明显缺乏了解:我们于 2012 年 1 月至 2 月和 2018 年 9 月至 10 月期间在肯尼亚西部维多利亚湖地区进行了八次基于学校的横断面疟疾测量调查。在每次调查中,我们从大陆 Ungoye 村的一所学校和 Mfangano 岛上每个集水区的每所学校中随机抽取了至少 100 名 3 至 15 岁的儿童。疟原虫感染情况通过显微镜和巢式聚合酶链反应(PCR)进行检测。多种类抽签(MKL)模型计算了人群中疟原虫感染的预期分布,并使用卡方检验(χ2)将其与观察值进行比较:显微镜检测的疟原虫感染率为 25.9%(2521/9724),PCR 检测的疟原虫感染率为 51.1%(4969/9724)。在 PCR 检测到的所有感染中,疟原虫、疟疾疟原虫(Pm)和卵形疟原虫(Po)单一感染分别占 58.6%、3.1% 和 1.8%。Pf/Pm、Pf/Po、Pm/Po 和 Pf/Pm/Po 合并感染的比例分别为 23.5%、4.3%、0.1% 和 8.6%。本研究揭示了 Pf 与 Pm 和/或 Po 之间潜在的相互作用。鉴于混合物种感染的临床意义,迫切需要改进 Pm 和 Po 的诊断和病例管理。
{"title":"Non-random distribution of Plasmodium Species infections and associated clinical features in children in the lake Victoria region, Kenya, 2012-2018.","authors":"Protus Omondi, Brian Musyoka, Takatsugu Okai, James Kongere, Wataru Kagaya, Chim W Chan, Mtakai Ngara, Bernard N Kanoi, Yasutoshi Kido, Jesse Gitaka, Akira Kaneko","doi":"10.1186/s41182-024-00622-3","DOIUrl":"10.1186/s41182-024-00622-3","url":null,"abstract":"<p><strong>Background: </strong>While Plasmodium falciparum (Pf) stands out as the most lethal malaria parasite species in humans, the impact of other species should not be dismissed. Moreover, there is a notable lack of understanding of mixed-species infections and their clinical implications.</p><p><strong>Methods: </strong>We conducted eight school-based cross-sectional malariometric surveys in the Lake Victoria region of western Kenya between January-February 2012 and September-October 2018. In each survey, a minimum of 100 children aged 3 to 15 years were randomly chosen from a school in Ungoye village on the mainland and as well as from each school selected in every catchment area on Mfangano island. Plasmodium infection was determined by microscopy and nested polymerase chain reaction (PCR). The multiple-kind lottery (MKL) model calculated the expected distribution of Plasmodium infections in the population and compared it to observed values using a chi-squared test (χ<sup>2</sup>).</p><p><strong>Results: </strong>The Plasmodium prevalence was 25.9% (2521/9724) by microscopy and 51.1% (4969/9724) by PCR. Among all infections detected by PCR, Pf, P. malariae (Pm), and P. ovale (Po) mono-infections were 58.6%, 3.1%, and 1.8%, respectively. Pf/Pm, Pf/Po, Pm/Po, and Pf/Pm/Po co-infections were 23.5%, 4.3%, 0.1%, and 8.6%, respectively. MKL modelling revealed non-random distributions, with frequencies of Pf/Pm and Pf/Pm/Po co-infections being significantly higher than expected (χ<sup>2</sup> = 3385.60, p < 0.001). Pf co-infections with Pm and Po were associated with a decreased risk of fever (aOR 0.64, 95% CI 0.46-0.83; p = 0.01) and increased risks of splenomegaly (aOR 12.79, 95% CI 9.69-16.9; p < 0.001) and anaemia (aOR 2.57, 95% CI 2.09-3.15; p < 0.001), compared to single-species infections.</p><p><strong>Conclusion: </strong>This study sheds light on the potential interaction between Pf and Pm and/or Po. Given the clinical significance of mixed-species infections, improved diagnostics, and case management of Pm and Po are urgently needed.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11299388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatio-temporal occurrence and habitat characteristics of Aedes aegypti (Diptera: Culicidae) larvae in Southern Afar region, Ethiopia. 埃塞俄比亚南阿法尔地区埃及伊蚊(双翅目:幼虫科)幼虫的时空分布和栖息地特征。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-08-02 DOI: 10.1186/s41182-024-00612-5
Mohammed Seid, Esayas Aklilu, Abebe Animut

Background: Describing spatio-temporal occurrence and habitat characteristics of Aedes mosquito larvae is crucial for the control of Aedes borne viral diseases. This study assessed spatio-temporal abundance and habitat characteristics of Aedes larvae in the Southern Afar Region, Ethiopia.

Methods: Immature mosquitoes were surveyed in Awash Sebat, Awash Arba, and Werer towns of the Southern Afar Region once per month from May 2022 to April 2023. Larvae and pupae surveys were carried out along the available water-holding containers. The collected larvae/pupae were reared to adults and identified by  species/genus morphologically. The physical and chemical properties of the habitats were also characterized.

Results: A total of 9099 Aedes larvae/pupae were collected, of which 53.6% (4875) were from Awash Sebat, 29.5% (2687) from Awash Arba and 16.9% (1537) from Werer. Water-holding tyres harboured the highest number of Aedes larvae/pupae followed by water-storage drums. All the Aedes larvae/pupae reared to adults were morphologically identified as Aedes aegypti. The overall Container Index was 47.28%, House Index 18.19%, Breteau Index 59.94% and Pupal Index 171.94. Significant positive relations were observed in the occurrences of Ae. aegypti larvae/pupae with water-holding tyre (AOR = 15.89, CI = 3.55-71.09, p < 0.001), water storage drums (AOR = 19.84, CI = 4.64-84.89, p < 0.001), domestic habitat (AOR = 3.76, CI = 1.27-11.12, p = 0.017), and significant negative relations were observed with Ae. aegypti larvae/pupae occurrence and tap water source (AOR = 0.08, CI = 0.02-0.31, p = 0.001). Ae. aegypti larvae/pupae densities showed positive relations with dissolved oxygen (β = 0.523, p < 0.001) and total hardness (β = 0.475, p = 0.034) of water.

Conclusions: Diverse types of artificial water-holding containers were positive for Ae. aegypti larvae/pupae. Ae. aegypti larvae/pupae were abundant in used water-holding tyres, water storage drums, and cement tanks in Awash Sebat, Awash Arba, and Werer towns. This could  put the residents of the towns at high risk of infections with Ae. aegypti transmitted viral diseases such as chikungunya and dengue outbreaks. Thus, we recommend artificial water-holding container management as a strategy to control Ae. aegypti and hence the arboviral diseases transmission.

背景:描述伊蚊幼虫的时空分布和栖息地特征对于控制伊蚊传播的病毒性疾病至关重要。本研究评估了埃塞俄比亚南阿法尔地区伊蚊幼虫的时空丰度和栖息地特征:从 2022 年 5 月到 2023 年 4 月,在南阿法尔地区的 Awash Sebat、Awash Arba 和 Werer 镇每月调查一次未成熟蚊子。幼虫和蛹的调查沿着现有的盛水容器进行。收集到的幼虫/蛹被饲养成成虫,并按物种/属进行形态鉴定。此外,还对栖息地的物理和化学特性进行了鉴定:结果:共收集到 9099 头伊蚊幼虫/蛹,其中 53.6%(4875 头)来自阿瓦士塞巴特,29.5%(2687 头)来自阿瓦士阿尔巴,16.9%(1537 头)来自韦勒。蓄水轮胎中伊蚊幼虫/蛹的数量最多,其次是蓄水桶。所有饲养成虫的伊蚊幼虫/蛹经形态鉴定均为埃及伊蚊。总体容器指数为 47.28%,房舍指数为 18.19%,布雷图指数为 59.94%,蛹指数为 171.94。埃及伊蚊幼虫/蛹的出现与蓄水轮胎有显著的正相关关系(AOR = 15.89,CI = 3.55-71.09,p):不同类型的人工盛水容器对埃及蚁幼虫/蛹均呈阳性反应。在阿瓦什-塞巴特、阿瓦什-阿尔巴和韦勒镇,埃及蚁幼虫/蛹大量存在于旧的盛水轮胎、储水桶和水泥罐中。这可能会使这些城镇的居民面临感染埃及蚁传播的病毒性疾病(如基孔肯雅病和登革热爆发)的高风险。因此,我们建议将人工蓄水容器管理作为控制埃及蚁进而控制虫媒病毒疾病传播的一种策略。
{"title":"Spatio-temporal occurrence and habitat characteristics of Aedes aegypti (Diptera: Culicidae) larvae in Southern Afar region, Ethiopia.","authors":"Mohammed Seid, Esayas Aklilu, Abebe Animut","doi":"10.1186/s41182-024-00612-5","DOIUrl":"10.1186/s41182-024-00612-5","url":null,"abstract":"<p><strong>Background: </strong>Describing spatio-temporal occurrence and habitat characteristics of Aedes mosquito larvae is crucial for the control of Aedes borne viral diseases. This study assessed spatio-temporal abundance and habitat characteristics of Aedes larvae in the Southern Afar Region, Ethiopia.</p><p><strong>Methods: </strong>Immature mosquitoes were surveyed in Awash Sebat, Awash Arba, and Werer towns of the Southern Afar Region once per month from May 2022 to April 2023. Larvae and pupae surveys were carried out along the available water-holding containers. The collected larvae/pupae were reared to adults and identified by  species/genus morphologically. The physical and chemical properties of the habitats were also characterized.</p><p><strong>Results: </strong>A total of 9099 Aedes larvae/pupae were collected, of which 53.6% (4875) were from Awash Sebat, 29.5% (2687) from Awash Arba and 16.9% (1537) from Werer. Water-holding tyres harboured the highest number of Aedes larvae/pupae followed by water-storage drums. All the Aedes larvae/pupae reared to adults were morphologically identified as Aedes aegypti. The overall Container Index was 47.28%, House Index 18.19%, Breteau Index 59.94% and Pupal Index 171.94. Significant positive relations were observed in the occurrences of Ae. aegypti larvae/pupae with water-holding tyre (AOR = 15.89, CI = 3.55-71.09, p < 0.001), water storage drums (AOR = 19.84, CI = 4.64-84.89, p < 0.001), domestic habitat (AOR = 3.76, CI = 1.27-11.12, p = 0.017), and significant negative relations were observed with Ae. aegypti larvae/pupae occurrence and tap water source (AOR = 0.08, CI = 0.02-0.31, p = 0.001). Ae. aegypti larvae/pupae densities showed positive relations with dissolved oxygen (β = 0.523, p < 0.001) and total hardness (β = 0.475, p = 0.034) of water.</p><p><strong>Conclusions: </strong>Diverse types of artificial water-holding containers were positive for Ae. aegypti larvae/pupae. Ae. aegypti larvae/pupae were abundant in used water-holding tyres, water storage drums, and cement tanks in Awash Sebat, Awash Arba, and Werer towns. This could  put the residents of the towns at high risk of infections with Ae. aegypti transmitted viral diseases such as chikungunya and dengue outbreaks. Thus, we recommend artificial water-holding container management as a strategy to control Ae. aegypti and hence the arboviral diseases transmission.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11295501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dengue virus type 3 infection in a traveler returning from Costa Rica to Japan in 2023. 2023 年一名从哥斯达黎加返回日本的旅客感染 3 型登革热病毒。
IF 3.6 Q1 TROPICAL MEDICINE Pub Date : 2024-08-01 DOI: 10.1186/s41182-024-00620-5
Tadahiro Sasaki, Ryo Morita, Ikuko Aoyama, Takashi Baba, Tetsushi Goto, Ritsuko Kubota-Koketsu, Yoshihiro Samune, Emi E Nakayama, Tatsuo Shioda, Michinori Shirano

The number of dengue cases has increased dramatically in recent years. In Latin America, the number of cases and deaths in 2023 was the highest ever recorded. We report on a patient who had been infected with dengue virus during his stay in Costa Rica in September 2023, and developed the disease after returning to Japan. Plasma obtained from the patient was used for diagnosis and dengue virus serotyping by real-time PCR. The nucleotide sequence of the envelope region of dengue virus was then determined by the direct sequencing method, and this sequence was used for phylogenetic analyses. The patient was found to be infected with dengue virus type 3 genotype III. The sequence from the present case was more homologous with sequences registered in Florida, USA, associated with travel to Cuba in 2022 than with sequences registered in Costa Rica 10 years ago. The Pan American Health Organization reported that only dengue virus type 1 and 2 cases were reported in Costa Rica in 2019-2021, whereas dengue virus type 3 and 4 cases started being reported in 2022. In 2023, the reported numbers of cases with dengue virus types 3 and 4 exceeded those of dengue virus types 1 and 2. In addition, regional differences in endemic strains have been observed in Costa Rica. Our findings suggest that the dengue virus type 3 that infected the patient was more likely an influx of a strain that had been circulating in Caribbean countries such as Cuba in recent years, rather than a re-emergence of an indigenous virus in Costa Rica. The serotypes of dengue virus prevalent in Costa Rica have been changing since 2022. All four serotypes were prevalent in 2023, with a particularly sharp increase in the number of cases of dengue virus types 3 and 4. Future monitoring and surveillance are essential because changes in endemic serotypes can cause antibody-dependent enhancement, which can lead to severe dengue disease presentations.

近年来,登革热病例数量急剧增加。在拉丁美洲,2023 年的病例数和死亡人数均创下历史最高纪录。我们报告了一名于 2023 年 9 月在哥斯达黎加逗留期间感染登革热病毒,并在返回日本后发病的患者。从该患者身上获取的血浆用于诊断,并通过实时 PCR 对登革热病毒进行血清分型。然后通过直接测序法测定了登革热病毒包膜区的核苷酸序列,并将该序列用于系统发育分析。结果发现该患者感染了登革病毒 3 型基因 III 型。与 10 年前在哥斯达黎加登记的序列相比,该病例的序列与 2022 年在美国佛罗里达州登记的与古巴旅行有关的序列同源性更高。泛美卫生组织报告称,2019-2021 年哥斯达黎加只报告了 1 型和 2 型登革热病例,而 3 型和 4 型登革热病例从 2022 年开始报告。2023 年,报告的 3 型和 4 型登革热病毒病例数超过了 1 型和 2 型登革热病毒病例数。此外,在哥斯达黎加还观察到流行毒株的地区差异。我们的研究结果表明,感染该患者的 3 型登革热病毒更有可能是近年来在古巴等加勒比国家流行的病毒株的流入,而不是哥斯达黎加本土病毒的再次出现。自 2022 年以来,哥斯达黎加流行的登革热病毒血清型一直在变化。2023 年,所有四种血清型都很流行,登革热病毒 3 型和 4 型的病例数尤其急剧增加。未来的监测和监控至关重要,因为流行血清型的变化可能会导致抗体依赖性增强,从而导致登革热病的严重表现。
{"title":"Dengue virus type 3 infection in a traveler returning from Costa Rica to Japan in 2023.","authors":"Tadahiro Sasaki, Ryo Morita, Ikuko Aoyama, Takashi Baba, Tetsushi Goto, Ritsuko Kubota-Koketsu, Yoshihiro Samune, Emi E Nakayama, Tatsuo Shioda, Michinori Shirano","doi":"10.1186/s41182-024-00620-5","DOIUrl":"10.1186/s41182-024-00620-5","url":null,"abstract":"<p><p>The number of dengue cases has increased dramatically in recent years. In Latin America, the number of cases and deaths in 2023 was the highest ever recorded. We report on a patient who had been infected with dengue virus during his stay in Costa Rica in September 2023, and developed the disease after returning to Japan. Plasma obtained from the patient was used for diagnosis and dengue virus serotyping by real-time PCR. The nucleotide sequence of the envelope region of dengue virus was then determined by the direct sequencing method, and this sequence was used for phylogenetic analyses. The patient was found to be infected with dengue virus type 3 genotype III. The sequence from the present case was more homologous with sequences registered in Florida, USA, associated with travel to Cuba in 2022 than with sequences registered in Costa Rica 10 years ago. The Pan American Health Organization reported that only dengue virus type 1 and 2 cases were reported in Costa Rica in 2019-2021, whereas dengue virus type 3 and 4 cases started being reported in 2022. In 2023, the reported numbers of cases with dengue virus types 3 and 4 exceeded those of dengue virus types 1 and 2. In addition, regional differences in endemic strains have been observed in Costa Rica. Our findings suggest that the dengue virus type 3 that infected the patient was more likely an influx of a strain that had been circulating in Caribbean countries such as Cuba in recent years, rather than a re-emergence of an indigenous virus in Costa Rica. The serotypes of dengue virus prevalent in Costa Rica have been changing since 2022. All four serotypes were prevalent in 2023, with a particularly sharp increase in the number of cases of dengue virus types 3 and 4. Future monitoring and surveillance are essential because changes in endemic serotypes can cause antibody-dependent enhancement, which can lead to severe dengue disease presentations.</p>","PeriodicalId":23311,"journal":{"name":"Tropical Medicine and Health","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11292857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Tropical Medicine and Health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1