Pub Date : 2023-01-01DOI: 10.26907/2542-064x.2023.2.308-321
R. Kutygin, V. Makoshin
An extensive collection of fossil brachiopods, all assigned to the Wuchiapingian Stage, was recovered from the lower part of the Imtachan Formation along the Ustupnyi Creek (right tributary of the Setorym River) in the Southern Verkhoyanie. It comprises strophalosiids (Strophalosia? aff. vollossovitschi (Fredericks), Strophalosia? sp., Subtaeniothaerus lungersgauzeni Solomina, Marginalosia? magna Abramov et Grigorjeva), spiriferids (Crassispirifer monumentalis Abramov et Grigorjeva, Crassispirifer cf. monumentalis Abramov et Grigorjeva, Crassispirifer sp.), athyridids (Cleiothyridina nikolaevi Grunt, Cleiothyridina sp. 1, Bajtugania sp.), and terebratulids (Marinurnula? aff. mantuanensis (Campbell), Marinurnula? sp.). The identified assemblage is associated with brachiopods from the lower part of the Khalpirki Formation of the Western Verkhoyanie, the appearance of which marks the boundary between the Dulgalakhian and Khalpirkian Regional Stages and also substantiates the lower boundary of the Crassispirifer monumentalis Zone. Single finds of Crassispirifer cf. monumentalis in the lower part of the Middle Imtachan Subformation indicate that the entire lower subformation and the lower part of the middle subformation belong to the C. monumentalis Zone. There are no reliable finds of brachiopods at higher levels of the Imtachan Formation.
{"title":"Brachiopods of the Imtachan Formation in the Upper Permian of the Southern Verkhoyanie, Northeast Russia","authors":"R. Kutygin, V. Makoshin","doi":"10.26907/2542-064x.2023.2.308-321","DOIUrl":"https://doi.org/10.26907/2542-064x.2023.2.308-321","url":null,"abstract":"An extensive collection of fossil brachiopods, all assigned to the Wuchiapingian Stage, was recovered from the lower part of the Imtachan Formation along the Ustupnyi Creek (right tributary of the Setorym River) in the Southern Verkhoyanie. It comprises strophalosiids (Strophalosia? aff. vollossovitschi (Fredericks), Strophalosia? sp., Subtaeniothaerus lungersgauzeni Solomina, Marginalosia? magna Abramov et Grigorjeva), spiriferids (Crassispirifer monumentalis Abramov et Grigorjeva, Crassispirifer cf. monumentalis Abramov et Grigorjeva, Crassispirifer sp.), athyridids (Cleiothyridina nikolaevi Grunt, Cleiothyridina sp. 1, Bajtugania sp.), and terebratulids (Marinurnula? aff. mantuanensis (Campbell), Marinurnula? sp.). The identified assemblage is associated with brachiopods from the lower part of the Khalpirki Formation of the Western Verkhoyanie, the appearance of which marks the boundary between the Dulgalakhian and Khalpirkian Regional Stages and also substantiates the lower boundary of the Crassispirifer monumentalis Zone. Single finds of Crassispirifer cf. monumentalis in the lower part of the Middle Imtachan Subformation indicate that the entire lower subformation and the lower part of the middle subformation belong to the C. monumentalis Zone. There are no reliable finds of brachiopods at higher levels of the Imtachan Formation.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"20 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79210811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.26907/2542-064x.2023.1.49-57
D. Gerasimova, L. V. Frantsuzova, R. Fayzullin, O. Lodochnikova
A theoretical study of the association of phenyl and ortho-substituted aryl derivatives of lactic acid was carried out. Two variants of hydrogen-bonded associates in the gas phase were calculated: non-classical, actually found in the crystals, and simulated classical dimers. The energy advantage of classical dimers and the non-equivalence of diastereotopic electron lone pairs at the carbonyl oxygen atom were shown.
{"title":"Theoretical Study of the Association of Aryl Derivatives of Lactic Acid","authors":"D. Gerasimova, L. V. Frantsuzova, R. Fayzullin, O. Lodochnikova","doi":"10.26907/2542-064x.2023.1.49-57","DOIUrl":"https://doi.org/10.26907/2542-064x.2023.1.49-57","url":null,"abstract":"A theoretical study of the association of phenyl and ortho-substituted aryl derivatives of lactic acid was carried out. Two variants of hydrogen-bonded associates in the gas phase were calculated: non-classical, actually found in the crystals, and simulated classical dimers. The energy advantage of classical dimers and the non-equivalence of diastereotopic electron lone pairs at the carbonyl oxygen atom were shown.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"32 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81582274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.26907/2542-064x.2022.1.94-108
Z. Tolokonnikova
{"title":"Geological Heritage of the Northwestern Caucasus and Its Importance for Promoting a Better Understanding of the Earth’s Structure and Evolution","authors":"Z. Tolokonnikova","doi":"10.26907/2542-064x.2022.1.94-108","DOIUrl":"https://doi.org/10.26907/2542-064x.2022.1.94-108","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"82 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73991359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.26907/2542-064x.2022.3.347-366
I. Filin, K. Kitaeva, A. Rizvanov, V. Solovyeva
Recent advances in cancer immunotherapy have steadily increased the effectiveness of standard antitumor therapy methods. Due to their low toxicity and simple production process, personalized therapeutic vaccines based on dendritic cells are of particular clinical interest. A striking fact is that the first attempts to use such vaccines in clinical practice were discouraging. However, their scope and effectiveness were subsequently greatly enhanced by the development of new approaches to activating and loading dendritic cells with tumor-associated antigens, as well as by their use as an adjuvant in combination with other therapeutic methods for cancer treatment. This review considers new techniques and the latest achievements in the development of dendritic vaccines that ensure their clinical success
{"title":"Current State and Prospects of Using Dendritic Cell Vaccination for Cancer Immunotherapy","authors":"I. Filin, K. Kitaeva, A. Rizvanov, V. Solovyeva","doi":"10.26907/2542-064x.2022.3.347-366","DOIUrl":"https://doi.org/10.26907/2542-064x.2022.3.347-366","url":null,"abstract":"Recent advances in cancer immunotherapy have steadily increased the effectiveness of standard antitumor therapy methods. Due to their low toxicity and simple production process, personalized therapeutic vaccines based on dendritic cells are of particular clinical interest. A striking fact is that the first attempts to use such vaccines in clinical practice were discouraging. However, their scope and effectiveness were subsequently greatly enhanced by the development of new approaches to activating and loading dendritic cells with tumor-associated antigens, as well as by their use as an adjuvant in combination with other therapeutic methods for cancer treatment. This review considers new techniques and the latest achievements in the development of dendritic vaccines that ensure their clinical success","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"57 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89834483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.26907/2542-064x.2022.1.109-134
A. Kedich, V. Golosov, S. Kharchenko
{"title":"Surface Processes in Mountainous Proglacial Areas: Quantitative Assessments and Their Accuracy","authors":"A. Kedich, V. Golosov, S. Kharchenko","doi":"10.26907/2542-064x.2022.1.109-134","DOIUrl":"https://doi.org/10.26907/2542-064x.2022.1.109-134","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"5 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88139779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.26907/2542-064x.2022.2.328-341
G. Polynova, O. E. Polynova
{"title":"Toad-Headed Agama (Phrynocephalus mystaceus Pallas): The State of the Population on the Sarykum Sand Massif (Dagestan, Russia)","authors":"G. Polynova, O. E. Polynova","doi":"10.26907/2542-064x.2022.2.328-341","DOIUrl":"https://doi.org/10.26907/2542-064x.2022.2.328-341","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81955424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.26907/2542-064x.2022.4.633-669
A. Zubov
{"title":"Current Status and Problems of Magnetostratigraphic Scale Development for Kamchatka in the Brunhes Epoch. Part 1. Theoretical Aspect","authors":"A. Zubov","doi":"10.26907/2542-064x.2022.4.633-669","DOIUrl":"https://doi.org/10.26907/2542-064x.2022.4.633-669","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"88 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78176002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.26907/2542-064x.2022.2.231-248
A. Parfenov, A. Vyshtakalyuk, I. Galyametdinova, V. Semenov, V. Zobov
{"title":"Anti-Apoptosis Mechanism of the Hepatoprotective Effect of Pyrimidine Derivatives in In Vivo Studies","authors":"A. Parfenov, A. Vyshtakalyuk, I. Galyametdinova, V. Semenov, V. Zobov","doi":"10.26907/2542-064x.2022.2.231-248","DOIUrl":"https://doi.org/10.26907/2542-064x.2022.2.231-248","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"67 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73496560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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