Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.4.557-568
V. Vershinina, E. Dudkina, V. Ulyanova, V. A. Kalashnikov, O. Ilinskaya
{"title":"Specific Antibodies against Binase: Preparation and Application","authors":"V. Vershinina, E. Dudkina, V. Ulyanova, V. A. Kalashnikov, O. Ilinskaya","doi":"10.26907/2542-064x.2021.4.557-568","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.4.557-568","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75129566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.2.155-176
K. Kitaeva, A. A. Rizvanov, V. Solovyeva
{"title":"Modern Methods of Preclinical Anticancer Drug Screening Using Test Systems Based on Cell Cultures","authors":"K. Kitaeva, A. A. Rizvanov, V. Solovyeva","doi":"10.26907/2542-064x.2021.2.155-176","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.2.155-176","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82094835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.4.603-625
A. Vorobyov, V.A. Krivtcov, A. Kadyrov
,
，
{"title":"Current Dynamics of Accumulation and Composition of Alluvium in the Near-Channel Floodplain of the Oka River (Russia)","authors":"A. Vorobyov, V.A. Krivtcov, A. Kadyrov","doi":"10.26907/2542-064x.2021.4.603-625","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.4.603-625","url":null,"abstract":",","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76304021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.2.302-319
E. V. Polyakova, Y. Kutinov, A. Mineev, Z. Chistova, T. Belenovich
The possibility of applying the method of detecting drainless depressions, which is used in hydrological correction of the digital elevation model, to identify areas of probable activation of the karst processes in the territory of the Arkhangelsk region was considered. This approach is especially relevant for northern forested territories subjected to continuously increasing anthropogenic activity. Errors (depressions) eliminated by the hydrological correction procedure are not always false. They can be natural landforms, especially in karst areas. Hydrological correction of the digital elevation model of the Arkhangelsk region (based on ASTER GDEM v.2) was performed. A vector layer of depressions in the region was obtained. The density of drainless depressions per unit area was calculated. The resulting map showing the density of drainless depressions was compared with the distribution of karst rocks in the Arkhangelsk region. It was found that the areas of maximum open karst development are associated with a low density of drainless depressions. The highest density of drainless depressions occurs in the territory with carbonate-covered and buried karst.
{"title":"Using the ASTER GDEM v.2 Global Digital Elevation Model to Identify Areas of Possible Activation of Karst Processes in the Arkhangelsk Region (Russia)","authors":"E. V. Polyakova, Y. Kutinov, A. Mineev, Z. Chistova, T. Belenovich","doi":"10.26907/2542-064x.2021.2.302-319","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.2.302-319","url":null,"abstract":"The possibility of applying the method of detecting drainless depressions, which is used in hydrological correction of the digital elevation model, to identify areas of probable activation of the karst processes in the territory of the Arkhangelsk region was considered. This approach is especially relevant for northern forested territories subjected to continuously increasing anthropogenic activity. Errors (depressions) eliminated by the hydrological correction procedure are not always false. They can be natural landforms, especially in karst areas. Hydrological correction of the digital elevation model of the Arkhangelsk region (based on ASTER GDEM v.2) was performed. A vector layer of depressions in the region was obtained. The density of drainless depressions per unit area was calculated. The resulting map showing the density of drainless depressions was compared with the distribution of karst rocks in the Arkhangelsk region. It was found that the areas of maximum open karst development are associated with a low density of drainless depressions. The highest density of drainless depressions occurs in the territory with carbonate-covered and buried karst.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83916758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.3.406-413
V. Makoshin, R. Kutygin
{"title":"Biostratigraphy of the Terminal Carboniferous of the Lower Reaches of the Lena River (Kubalakh Section, Russia)","authors":"V. Makoshin, R. Kutygin","doi":"10.26907/2542-064x.2021.3.406-413","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.3.406-413","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83376708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.3.444-465
A. Bakaev, V. V. Bulanov, I. Ilaltdinov, D. Kozhanov, G. Ponomareva, I. Khopta
The Kueda-Klyuchiki locality of Permian vertebrates located in the south of the Perm Region in the Kuedinsky District was discovered in 2005 and quickly became known among paleontologists. The locality contains a rich complex of exceptionally preserved plants and vertebrates (fish, amphibians, and reptiles). Their remains are confined to limestones of various textures, which form two bone-bearing beds in the section of the quarry. However, the age of rocks remains a controversial issue. This research aims to analyze and compare various stratigraphic markers and discuss a number of existing stratigraphic inconsistencies in an attempt to arrive at a general conclusion about the age of the locality. According to geological survey data on a scale of 1:200 000, the Buraevo Sequence (Sheshmian Formation, Ufimian Stage) was identified in the territory of the quarry. At the boundary of the Sheshmian and Belebey Formations, a mineralogical “boundary” is observed, which is manifested in a decrease
{"title":"The Problem of Dating the Kuyeda-Klyuchiki Section – a Unique Locality of Permian Vertebrates (Perm Region, Russia)","authors":"A. Bakaev, V. V. Bulanov, I. Ilaltdinov, D. Kozhanov, G. Ponomareva, I. Khopta","doi":"10.26907/2542-064x.2021.3.444-465","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.3.444-465","url":null,"abstract":"The Kueda-Klyuchiki locality of Permian vertebrates located in the south of the Perm Region in the Kuedinsky District was discovered in 2005 and quickly became known among paleontologists. The locality contains a rich complex of exceptionally preserved plants and vertebrates (fish, amphibians, and reptiles). Their remains are confined to limestones of various textures, which form two bone-bearing beds in the section of the quarry. However, the age of rocks remains a controversial issue. This research aims to analyze and compare various stratigraphic markers and discuss a number of existing stratigraphic inconsistencies in an attempt to arrive at a general conclusion about the age of the locality. According to geological survey data on a scale of 1:200 000, the Buraevo Sequence (Sheshmian Formation, Ufimian Stage) was identified in the territory of the quarry. At the boundary of the Sheshmian and Belebey Formations, a mineralogical “boundary” is observed, which is manifested in a decrease","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72855282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.3.338-350
F. Scholze, A. Pint
A variety of formulas can be found in the literature to convert geochemical data into absolute palaeotemperatures. In the present study, we test a formula for calculating the Early Permian (Artinskian) palaeotemperatures based on major element values from continental red-bed deposits of the Tambach Sandstone Member (Tambach Formation, Rotliegend Group) in Germany. The geochemical data used herein were extracted from a previous study on the Bromacker section. Applying the literature-based dataset constitutes the first approach aimed to a better understanding of certain local palaeoclimate aspects (i.e., mean annual temperature) and can be easily expanded to wider stratigraphic and palaeogeographic ranges through future studies.
在文献中可以找到各种公式将地球化学数据转换为绝对古温度。在本研究中，我们测试了一个基于德国Rotliegend Group Tambach组陆相红层沉积主要元素值计算早二叠世(Artinskian)古地温的公式。本文使用的地球化学数据来自先前对Bromacker剖面的研究。应用基于文献的数据集是第一个旨在更好地理解某些局部古气候方面(即年平均温度)的方法，并且可以通过未来的研究轻松扩展到更广泛的地层和古地理范围。
{"title":"Early Permian Palaeotemperature Values Proposed for Continental Red-Bed Deposits of the Tambach Formation at the Bromacker Section","authors":"F. Scholze, A. Pint","doi":"10.26907/2542-064x.2021.3.338-350","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.3.338-350","url":null,"abstract":"A variety of formulas can be found in the literature to convert geochemical data into absolute palaeotemperatures. In the present study, we test a formula for calculating the Early Permian (Artinskian) palaeotemperatures based on major element values from continental red-bed deposits of the Tambach Sandstone Member (Tambach Formation, Rotliegend Group) in Germany. The geochemical data used herein were extracted from a previous study on the Bromacker section. Applying the literature-based dataset constitutes the first approach aimed to a better understanding of certain local palaeoclimate aspects (i.e., mean annual temperature) and can be easily expanded to wider stratigraphic and palaeogeographic ranges through future studies.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77529200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.2.289-301
T. Shikhova, Kirov Russia Fur Farming, A. Soloviev
Using the phenological database covering the period of 1961–2019 for Kirov (58°36' N, 49°40' E), the regional features of changes in the seasonal rhythms were analyzed. Mean values were calculated for 1981–2010. Additional types of seasonal rhythms with parameters deviating from the mean values by more than ±2σ were identified. The normal onset of spring, summer, and autumn was more characteristic of the 2000s (50–70%), while the anomalous seasons (with the onset dates and duration deviating significantly from the norm) prevailed in 1991–2000 and 2010–2019, respectively. The trend of variability in the ratio of phenological seasons (shorter winter and spring, longer summer and autumn) began in the middle of the 20th century and has persisted so far. In the last 30 years, compared with the base period of 1961–1990, winter and spring have begun later, but the onsets of summer and autumn have taken place earlier. The duration of winter and spring has kept decreasing. Summer has lengthened slightly. Autumn has become significantly longer. A negative correlation was established between the durations of autumn and winter ( r = –0.65), autumn and spring ( r = –0.61). The revealed phenological trends of the 21st century (the shift in the onset of the seasons, as well as the change in their duration and the increase in the amplitude of their time parameters) have been consistent with the modern restructuring of the climate regime. The data obtained on the dynamics of the natural seasons are important for assessing the response of natural ecosystems in the region to weather and climate fluctuations.
{"title":"Dynamics of the Borders of Phenological Seasons in the East of the Russian Plain (Kirov, Russia)","authors":"T. Shikhova, Kirov Russia Fur Farming, A. Soloviev","doi":"10.26907/2542-064x.2021.2.289-301","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.2.289-301","url":null,"abstract":"Using the phenological database covering the period of 1961–2019 for Kirov (58°36' N, 49°40' E), the regional features of changes in the seasonal rhythms were analyzed. Mean values were calculated for 1981–2010. Additional types of seasonal rhythms with parameters deviating from the mean values by more than ±2σ were identified. The normal onset of spring, summer, and autumn was more characteristic of the 2000s (50–70%), while the anomalous seasons (with the onset dates and duration deviating significantly from the norm) prevailed in 1991–2000 and 2010–2019, respectively. The trend of variability in the ratio of phenological seasons (shorter winter and spring, longer summer and autumn) began in the middle of the 20th century and has persisted so far. In the last 30 years, compared with the base period of 1961–1990, winter and spring have begun later, but the onsets of summer and autumn have taken place earlier. The duration of winter and spring has kept decreasing. Summer has lengthened slightly. Autumn has become significantly longer. A negative correlation was established between the durations of autumn and winter ( r = –0.65), autumn and spring ( r = –0.61). The revealed phenological trends of the 21st century (the shift in the onset of the seasons, as well as the change in their duration and the increase in the amplitude of their time parameters) have been consistent with the modern restructuring of the climate regime. The data obtained on the dynamics of the natural seasons are important for assessing the response of natural ecosystems in the region to weather and climate fluctuations.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90819005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.4.569-580
I. Fitsev, E. Rakhmetova, A. G. Mukhammetshina, K. E. Burkin, O. V. Shlyamina
{"title":"Gas Chromatography–Mass Spectrometry Determination of Deltamethrin in Food","authors":"I. Fitsev, E. Rakhmetova, A. G. Mukhammetshina, K. E. Burkin, O. V. Shlyamina","doi":"10.26907/2542-064x.2021.4.569-580","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.4.569-580","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90852054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.26907/2542-064x.2021.4.543-556
G. Andrianov, I. Serebriiskii
{"title":"Identification of New Inhibitors of the Kinase Activity of CDK2 and CDK9 by Molecular Modeling and High-Efficiency Screening","authors":"G. Andrianov, I. Serebriiskii","doi":"10.26907/2542-064x.2021.4.543-556","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.4.543-556","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72521443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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