Pub Date : 2023-04-29DOI: 10.32792/utq/utjsci/v10i1(si).996
Munther Kamil Oudha, Ahmad Shandookh Hameed, Lina Abdullah Naser
After the emergency approval of different COVID-19 vaccines the administration of millions of doses, many concerns arise for adverse effects, especially in vulnerable groups such as diabetics. In this study, we investigate what effects different COVID vaccines could have on several biomarkers in diabetic patients and whether that raises a concern for this group or not. Materials and methods: this study includes two groups of diabetics each group consists of 20 participants ; One of the groups under study, where they received the COVID-19 vaccine either AstraZeneca or Pifizr-BioNTech vaccine and the other groups were controlled or the Pfizer-BioNTech vaccine, the other group-the control group- did not take any vaccine. Blood samples were taken from both groups about a week after the first dose and statistical studies were conducted on the results. Results: Noticed an increase in all biomarkers. Increase in RBS could simply be due to immune response, same thing could be said for the CRP increase. Ferritin increase was not important; it was only apparent in three patients and that could be due to active infection. The increase in D-dimer levels was apparent in all patients and that raises the biggest concern. Conclusion: the biggest issue was seen in the rising of D-dimer levels because it raises concern about clotting disorders and heart disease which is already a concern for diabetic patients. Further investigation should be done and careful monitoring for clotting risks is necessary after the vaccine.
{"title":"Effect of different COVID-19 vaccines on some biomarkers in diabetics","authors":"Munther Kamil Oudha, Ahmad Shandookh Hameed, Lina Abdullah Naser","doi":"10.32792/utq/utjsci/v10i1(si).996","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).996","url":null,"abstract":"After the emergency approval of different COVID-19 vaccines the administration of millions of doses, many concerns arise for adverse effects, especially in vulnerable groups such as diabetics. In this study, we investigate what effects different COVID vaccines could have on several biomarkers in diabetic patients and whether that raises a concern for this group or not. Materials and methods: this study includes two groups of diabetics each group consists of 20 participants ; One of the groups under study, where they received the COVID-19 vaccine either AstraZeneca or Pifizr-BioNTech vaccine and the other groups were controlled or the Pfizer-BioNTech vaccine, the other group-the control group- did not take any vaccine. Blood samples were taken from both groups about a week after the first dose and statistical studies were conducted on the results. Results: Noticed an increase in all biomarkers. Increase in RBS could simply be due to immune response, same thing could be said for the CRP increase. Ferritin increase was not important; it was only apparent in three patients and that could be due to active infection. The increase in D-dimer levels was apparent in all patients and that raises the biggest concern. Conclusion: the biggest issue was seen in the rising of D-dimer levels because it raises concern about clotting disorders and heart disease which is already a concern for diabetic patients. Further investigation should be done and careful monitoring for clotting risks is necessary after the vaccine. \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89540197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.32792/utq/utjsci/v10i1(si).986
Abbas S. Musher, Majid A. Maatook, Dhaigham I. Atwan
the role of nutrition in developing pre-diabetes among obese children and adolescents remains a major problem. Method: A cross-sectional study based on food frequency questionnaire data was conducted on obese children and adolescents aged 6–18 years at Al-Faiha Specialized Diabetes, Endocrine, and Metabolism Center (FDEMC) in Basra (South Iraq) from November 1, 2021, to the end of May 2022. This study aimed to assess dietary patterns for obese children and adolescents who are at risk for pre-diabetes. Results: 155 obese children and adolescents aged 6–18 years participated in the study, 60% of whom were males and 40% female. 40% (n=62) had Impaired fasting glucose (IFG), and 16.8% (n=26) had Impaired glucose tolerance (IGT). Regarding the dietary pattern, this study discovered that 58.7% (n=91) of the participants have a neutral eating habits score, followed by 40.0% (n=62) of them have an unhealthy eating habits score, while only 1.3% (n = 2) of participants have healthy eating habits. However, this study found significant static associations between dietary habits and education level, socio-economic status, and father education. Conclusion: Healthy eating habits, weight reduction, and increased physical activity are all factors that assist in preventing pre-diabetes and its complication such as type 2 diabetes mellitus.
{"title":"Assessment of dietary patterns in obese children and adolescents at risk of pre-diabetes in Basra/Iraq","authors":"Abbas S. Musher, Majid A. Maatook, Dhaigham I. Atwan","doi":"10.32792/utq/utjsci/v10i1(si).986","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).986","url":null,"abstract":"the role of nutrition in developing pre-diabetes among obese children and adolescents remains a major problem. Method: A cross-sectional study based on food frequency questionnaire data was conducted on obese children and adolescents aged 6–18 years at Al-Faiha Specialized Diabetes, Endocrine, and Metabolism Center (FDEMC) in Basra (South Iraq) from November 1, 2021, to the end of May 2022. This study aimed to assess dietary patterns for obese children and adolescents who are at risk for pre-diabetes. Results: 155 obese children and adolescents aged 6–18 years participated in the study, 60% of whom were males and 40% female. 40% (n=62) had Impaired fasting glucose (IFG), and 16.8% (n=26) had Impaired glucose tolerance (IGT). Regarding the dietary pattern, this study discovered that 58.7% (n=91) of the participants have a neutral eating habits score, followed by 40.0% (n=62) of them have an unhealthy eating habits score, while only 1.3% (n = 2) of participants have healthy eating habits. However, this study found significant static associations between dietary habits and education level, socio-economic status, and father education. Conclusion: Healthy eating habits, weight reduction, and increased physical activity are all factors that assist in preventing pre-diabetes and its complication such as type 2 diabetes mellitus. \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80880808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.32792/utq/utjsci/v10i1(si).1022
Ola Abdul Shaheed Naser
Background; Since the emergence of the coronavirus disease pandemic, several effective vaccines have been introduced. These vaccines work through several different immunogenic pathways to produce effective immunity. There have been a number of reports of patients developing sub-acute thyroiditis and thyroid dysfunction after receiving the coronavirus (COVID-19) vaccine. This study aims to demonstrate the physiological effect of the covid -19 vaccine on human thyroid hormone. Methodology; For this purpose, 25 samples of male and female blood from people vaccinated with the corona virus used, 25 samples of blood from unvaccinated people were considered as a control group. The effect of this vaccine on the functions of the thyroid gland and on the concentrations of hormones was shown. A significant increase in the concentration of hormone T4 was observed in the group of vaccinated people compared to the control group. Conclusion, the current study Showed that the level of hormones increased significantly in the vaccinated compared to the control group, as well as concluded these results was indicate that thyroid function is negatively affected by the vaccine.
{"title":"Evaluation of thyroid function in people vaccinated against COVID-19 via Sinofarm type","authors":"Ola Abdul Shaheed Naser","doi":"10.32792/utq/utjsci/v10i1(si).1022","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).1022","url":null,"abstract":"Background; Since the emergence of the coronavirus disease pandemic, several effective vaccines have been introduced. These vaccines work through several different immunogenic pathways to produce effective immunity. There have been a number of reports of patients developing sub-acute thyroiditis and thyroid dysfunction after receiving the coronavirus (COVID-19) vaccine. This study aims to demonstrate the physiological effect of the covid -19 vaccine on human thyroid hormone. Methodology; For this purpose, 25 samples of male and female blood from people vaccinated with the corona virus used, 25 samples of blood from unvaccinated people were considered as a control group. The effect of this vaccine on the functions of the thyroid gland and on the concentrations of hormones was shown. A significant increase in the concentration of hormone T4 was observed in the group of vaccinated people compared to the control group. Conclusion, the current study Showed that the level of hormones increased significantly in the vaccinated compared to the control group, as well as concluded these results was indicate that thyroid function is negatively affected by the vaccine. \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74965287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical waste is a global issue because of its detrimental effects on societal safety and the environment. Due to its contagious and harmful nature, which can have negative consequences on people and the environment, medical waste treatment is crucial. Objective: assessment of the medical waste management during the Coronavirus epidemic was occurring in Al-Diwaniyah Hospitals. Methodology: A cross-sectional survey was used to carry out the investigation. To randomly select cases, a self-administered Arabic language questionnaire was used. The analysis uses SPSS Version 21. Results: General trash has been accounted for the majority of the waste produced in hospitals, with hazardous medical waste accounting for the second-highest percentage (63%) of waste handlers. In Al-Diwaniyah General Hospital, management levels were subpar, and medical waste management (MW) awareness among the entire medical teams was lacking.. the administrative employees, health professionals, and the cleaning staff did not have the necessary level of understanding concerning medical waste. The report suggests that integrated medical waste management should be clarified, suitable roles should be established, regulatory and legislative departments need to be supported, and increasing the training programs in the that medical institusion
医疗废物因其对社会安全和环境的有害影响而成为一个全球性问题。由于医疗废物具有传染性和有害性质，可能对人和环境产生负面影响，因此医疗废物的处理至关重要。目的:评估Al-Diwaniyah医院在冠状病毒流行期间的医疗废物管理情况。方法:采用横断面调查进行调查。为了随机选择病例，使用了自我管理的阿拉伯语问卷。分析使用SPSS Version 21。结果:医院产生的废物中一般垃圾占大多数，危险医疗废物占废物处理者的第二高百分比(63%)。在Al-Diwaniyah总医院，管理水平低于标准，整个医疗队缺乏医疗废物管理意识。行政人员、卫生专业人员和清洁人员对医疗废物没有必要的了解。该报告建议，应明确医疗废物综合管理，建立合适的角色，支持监管和立法部门，并增加该医疗机构的培训计划
{"title":"Assessment of the management of medical waste during the Coronavirus epidemic was occurring in Al-Diwaniyah Hospital","authors":"Razaq Rahi Hamlan, Alaa Kadhim Jasim, Atheer Kadhim Ibadi","doi":"10.32792/utq/utjsci/v10i1(si).1002","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).1002","url":null,"abstract":"Medical waste is a global issue because of its detrimental effects on societal safety and the environment. \u0000 Due to its contagious and harmful nature, which can have negative consequences on people and the environment, medical waste treatment is crucial. \u0000Objective: assessment of the medical waste management during the Coronavirus epidemic was occurring in Al-Diwaniyah Hospitals. \u0000Methodology: A cross-sectional survey was used to carry out the investigation. To randomly select cases, a self-administered Arabic language questionnaire was used. The analysis uses SPSS Version 21. \u0000Results: General trash has been accounted for the majority of the waste produced in hospitals, with hazardous medical waste accounting for the second-highest percentage (63%) of waste handlers. In Al-Diwaniyah General Hospital, management levels were subpar, and medical waste management (MW) awareness among the entire medical teams was lacking.. the administrative employees, health professionals, and the cleaning staff did not have the necessary level of understanding concerning medical waste. The report suggests that integrated medical waste management should be clarified, suitable roles should be established, regulatory and legislative departments need to be supported, and increasing the training programs in the that medical institusion \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79760775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.32792/utq/utjsci/v10i1(si).1024
Thaer Ali Hussein
Background:Infertility is a global problematic that impacts nearly 15% of all couples, and is definite as, incapability to conceive following 12 months of free-contraceptive un-protected interaction. Material and methodology:serum OD of anti-follicle hormone as stimulation antibody and anti-sperm antibody was identified through assay method of enzyme–linked immune-sorbent. One Protamine 1gene polymorphic sites was genotyped on 72 couple’s Sterility. Other 20 couples group was obviously healthy ones. Genotypes were assessed through (PCR-RFLP) method. Results: Regarding the Serum positivity of anti-sperm anti- body and anti-follicle stimulation hormone antibody in peripheral blood of sterile couples.The results observed significant association between anti-sperm antibody, anti-follicle stimulation hormone antibody and sterile women (P value 0.18, 0.32 respectively), while non-significant for anti-sperm antibody in sterile males P value (0.129), the reported SNP frequency was of no significance difference in comparison to males of normal fertility, that propose that the SNP might not aid as a good molecular genetic diagnosis indicator for males sterility (MI). Conclusions: The SNP G197T are absent totally and are not related to MI with above-mentioned, thus such SNPs might not signify as a molecular indicator for the MI genetic cause diagnosis in the current population of the study.
{"title":"The Polymorphism Function of Protamine 1 Gene and Some Immunological Factors in Sterile Couples","authors":"Thaer Ali Hussein","doi":"10.32792/utq/utjsci/v10i1(si).1024","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).1024","url":null,"abstract":"Background:Infertility is a global problematic that impacts nearly 15% of all couples, and is definite as, incapability to conceive following 12 months of free-contraceptive un-protected interaction. \u0000Material and methodology:serum OD of anti-follicle hormone as stimulation antibody and anti-sperm antibody was identified through assay method of enzyme–linked immune-sorbent. One Protamine 1gene polymorphic sites was genotyped on 72 couple’s Sterility. Other 20 couples group was obviously healthy ones. Genotypes were assessed through (PCR-RFLP) method. \u0000Results: Regarding the Serum positivity of anti-sperm anti- body and anti-follicle stimulation hormone antibody in peripheral blood of sterile couples.The results observed significant association between anti-sperm antibody, anti-follicle stimulation hormone antibody and sterile women (P value 0.18, 0.32 respectively), while non-significant for anti-sperm antibody in sterile males P value (0.129), the reported SNP frequency was of no significance difference in comparison to males of normal fertility, that propose that the SNP might not aid as a good molecular genetic diagnosis indicator for males sterility (MI). \u0000Conclusions: The SNP G197T are absent totally and are not related to MI with above-mentioned, thus such SNPs might not signify as a molecular indicator for the MI genetic cause diagnosis in the current population of the study. \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"179 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83750333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.32792/utq/utjsci/v10i1(si).968
Ryam S. Naeem, Abdulkareem M. Jewad, Rajaa A. Mahmoud
Background: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder that affects body systems and leads to reproductive and metabolic complications.Among women of reproductive age, it is considered as one of the main cause of infertility. The present study aimed to evaluate a biochemical hormones (FSH, LH, LH/FSH ratio and TESTO) of infertile women with and without polycystic ovarian syndrome in Basra City - Iraq, in order to know whether they represent biomarkers of polycystic ovarian syndrome. Method:The present study included 60 patients infertile women (30 with PCOS and 30 without PCOS) aged between 16 to 40 years, which was admitted to Infertility and IVF Centre in Basra Hospital for Women and Children (IbnGhazwan) in Basra Government-Southern Iraq. A control group of 30 entirely healthy participants with an age range of (16 -40) years were considered. Body mass index was calculatedfor the two groups. There follicle stimulating hormone, luteinizing hormone and testosterone were measured using enzyme-linked immunosorbent assay. Software of SPSS 26 was used for the statistical analysis. Results: The results of the present study showed a significant increase in each of (LH and LH/FSH) concentration in PCOS compared to the control. Moreover, the results illustrateda significant increase in patients without PCOS(LH and BMI)compared to the controls. Conclusion: The study concluded that there is a significant increase in LH, LH/FSH levels in addition to BMI among women with PCOS and without PCOS compared to Fertile women.
{"title":"A Biochemical Study of Infertile Women With and Without Polycystic Ovarian Syndrome in Basra City, Iraq","authors":"Ryam S. Naeem, Abdulkareem M. Jewad, Rajaa A. Mahmoud","doi":"10.32792/utq/utjsci/v10i1(si).968","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).968","url":null,"abstract":"Background: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder that affects body systems and leads to reproductive and metabolic complications.Among women of reproductive age, it is considered as one of the main cause of infertility. The present study aimed to evaluate a biochemical hormones (FSH, LH, LH/FSH ratio and TESTO) of infertile women with and without polycystic ovarian syndrome in Basra City - Iraq, in order to know whether they represent biomarkers of polycystic ovarian syndrome. \u0000Method:The present study included 60 patients infertile women (30 with PCOS and 30 without PCOS) aged between 16 to 40 years, which was admitted to Infertility and IVF Centre in Basra Hospital for Women and Children (IbnGhazwan) in Basra Government-Southern Iraq. A control group of 30 entirely healthy participants with an age range of (16 -40) years were considered. Body mass index was calculatedfor the two groups. There follicle stimulating hormone, luteinizing hormone and testosterone were measured using enzyme-linked immunosorbent assay. Software of SPSS 26 was used for the statistical analysis. \u0000Results: The results of the present study showed a significant increase in each of (LH and LH/FSH) concentration in PCOS compared to the control. Moreover, the results illustrateda significant increase in patients without PCOS(LH and BMI)compared to the controls. \u0000Conclusion: The study concluded that there is a significant increase in LH, LH/FSH levels in addition to BMI among women with PCOS and without PCOS compared to Fertile women. \u0000 \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80584000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Escherichia coli is a Gram-negative Bacilli belonging to the Enterobacteriaceae family. It has a rod-shaped coliform . A number of neuropsychiatric conditions, likeanxiety, schizophrenia, autism, bipolar disorder, and depressive disorder, Have been reported to be associated with the microbiome. Autism spectrum disorder (ASD), is a neurodevelopmental disturbance. A sample of fifteen E.coli bacteria were isolated E. coliisolates From ASD children's stools.ASD children. The isolates were identified by phenotypic identification using API 20 E. The molecular analysis was processed for Integron I,II,I, cfr, procfr genes.These resultsshowed Integron II less prevalence Than in IntegronIand III. I,III while pro-cfr, more prevalence than cfrgene.Multidrug-resistant in E. coli has widespread.
{"title":"Eschershia coli integrons and cfr, procfr genes identified from samples of autistic children's stools","authors":"Khwam Reissan Hussein, NimahJulud Al- Temimy, Qasim Hassan Widaa, Marwa Hassan Nasser","doi":"10.32792/utq/utjsci/v10i1(si).1020","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).1020","url":null,"abstract":"Escherichia coli is a Gram-negative Bacilli belonging to the Enterobacteriaceae family. It has a rod-shaped coliform . A number of neuropsychiatric conditions, likeanxiety, schizophrenia, autism, bipolar disorder, and depressive disorder, Have been reported to be associated with the microbiome. Autism spectrum disorder (ASD), is a neurodevelopmental disturbance. A sample of fifteen E.coli bacteria were isolated E. coliisolates From ASD children's stools.ASD children. The isolates were identified by phenotypic identification using API 20 E. The molecular analysis was processed for Integron I,II,I, cfr, procfr genes.These resultsshowed Integron II less prevalence Than in IntegronIand III. I,III while pro-cfr, more prevalence than cfrgene.Multidrug-resistant in E. coli has widespread. \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81037554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.32792/utq/utjsci/v10i1(si).984
Hasan Kareem Mohammed, Majid Abdulwahab Maatook, Rajaa Ahmed Mahmoud
Self-medication is described as the use of medications to address illnesses or symptoms that one has independently diagnosed, as well as the irregular or continuous use of a prescribed substance to treat persistent or recurrent illnesses or symptoms. The fundamental issue with antibiotic self-medication is the development of pathogenic resistance. Antibiotic resistance is an issue that exists today, primarily in developing nations. The main objective was to study the public's beliefs and behaviors on antibiotic use as well as self-medication with antibiotics in Basra were studied. Methods: a cross-sectional survey was conducted by using a validated questionnaire. This survey included 470 participants. (74 %) self-medicate with antibiotics. Community pharmacies (41.1%) were the most common source of antibiotics for self-medication. (74.5%) of the participants know that antibiotics are not useful for a common cold. (59.1%) of the participants have an idea of the possible harmful effects of using antibiotics. More than half of the participants 287 (61.1%) thought that self-medication with antibiotics is not an acceptable practice. (40.51%) stated as very bad practice and (32.72%) stated as bad practice. Conclusion: Most of the participants beliefs that self-medication with antibiotics is not an acceptable practice, while 74% used this practices. It is important to properly follow up the regulations and controlling the distribution of prescription medications.
{"title":"Public Knowledge and Beliefs on Antibiotics Use and Self-Medication in Basra","authors":"Hasan Kareem Mohammed, Majid Abdulwahab Maatook, Rajaa Ahmed Mahmoud","doi":"10.32792/utq/utjsci/v10i1(si).984","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).984","url":null,"abstract":"Self-medication is described as the use of medications to address illnesses or symptoms that one has independently diagnosed, as well as the irregular or continuous use of a prescribed substance to treat persistent or recurrent illnesses or symptoms. The fundamental issue with antibiotic self-medication is the development of pathogenic resistance. Antibiotic resistance is an issue that exists today, primarily in developing nations. \u0000The main objective was to study the public's beliefs and behaviors on antibiotic use as well as self-medication with antibiotics in Basra were studied. \u0000Methods: a cross-sectional survey was conducted by using a validated questionnaire. This survey included 470 participants. (74 %) self-medicate with antibiotics. Community pharmacies (41.1%) were the most common source of antibiotics for self-medication. (74.5%) of the participants know that antibiotics are not useful for a common cold. (59.1%) of the participants have an idea of the possible harmful effects of using antibiotics. More than half of the participants 287 (61.1%) thought that self-medication with antibiotics is not an acceptable practice. (40.51%) stated as very bad practice and (32.72%) stated as bad practice. \u0000Conclusion: Most of the participants beliefs that self-medication with antibiotics is not an acceptable practice, while 74% used this practices. It is important to properly follow up the regulations and controlling the distribution of prescription medications. \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81611912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.32792/utq/utjsci/v10i1(si).1028
Sarah Ali Nehmaa
One of the most important virulence factors produced by uropathogenicEscherichia coli (UPEC) is cytotoxic necrotizing factor 1 (CNF1). It plays a vital role in regulation of Ras homolog family member A (Rho), Ras-related C3 botulinum toxin substrate (Rac), and Cell division control protein 42 homolog (Cdc42)guanosine triphosphatase (GTPases) proteins, which involved in the organization of the actin cytoskeleton in eukaryotic cells. Also, CNF1may play a role in cell proliferation, surviving and gene transcription. Therefore, detection of the gene encoding CNF1 in UPEC would be imperative in characterization of these organisms and establishing a proper management regime to prevent the poor prognosis of the associated diseases. The aim of the present study was to investigatethe prevalence of the gene encoding cnf1 in UPEC strainsthat have been isolated from urinary tract infection and bladder cancer patients.Out of three hundred and fifty midstream urine samples, 136E. colistrains were isolated (98 urinary tract infection, 18 bladder cancer, and 20 healthy people). Detection and determination of the gene encoding CNF1 based on PCR technique and sequencing of PCR amplified target DNA. The present results showed that thirty five percent (35.34%) of the tested isolates have cnf1gene. All cnf1+strains were isolated from urinary tract infection patients. This finding should bring attention to predict the prognosis of the infections caused by these organisms and follow up patients to prevent any further complications.
{"title":"Distribution of CNF1among Escherichia coli isolates from urinary tract infection and bladder cancer in southern of Iraq","authors":"Sarah Ali Nehmaa","doi":"10.32792/utq/utjsci/v10i1(si).1028","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).1028","url":null,"abstract":"One of the most important virulence factors produced by uropathogenicEscherichia coli (UPEC) is cytotoxic necrotizing factor 1 (CNF1). It plays a vital role in regulation of Ras homolog family member A (Rho), Ras-related C3 botulinum toxin substrate (Rac), and Cell division control protein 42 homolog (Cdc42)guanosine triphosphatase (GTPases) proteins, which involved in the organization of the actin cytoskeleton in eukaryotic cells. Also, CNF1may play a role in cell proliferation, surviving and gene transcription. Therefore, detection of the gene encoding CNF1 in UPEC would be imperative in characterization of these organisms and establishing a proper management regime to prevent the poor prognosis of the associated diseases. The aim of the present study was to investigatethe prevalence of the gene encoding cnf1 in UPEC strainsthat have been isolated from urinary tract infection and bladder cancer patients.Out of three hundred and fifty midstream urine samples, 136E. colistrains were isolated (98 urinary tract infection, 18 bladder cancer, and 20 healthy people). Detection and determination of the gene encoding CNF1 based on PCR technique and sequencing of PCR amplified target DNA. The present results showed that thirty five percent (35.34%) of the tested isolates have cnf1gene. All cnf1+strains were isolated from urinary tract infection patients. This finding should bring attention to predict the prognosis of the infections caused by these organisms and follow up patients to prevent any further complications. \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"264 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86340406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.32792/utq/utjsci/v10i1(si).966
Asia Hameed Saddam, Majid Abdulwahab Maatook, Mahmood Thamer Altemimi
Glucocorticoids (GCs) are widely accessible over-the-counter (OTC), liberally recommended by locals medical practitioner, and frequently misused by women for the purpose of treatment of skin conditions, joint pains, febrile illnesses and asthma. Unfortunately, ladies misuse a lot of over-the-counter GCs and glucocorticoids containing cosmetic creams, both imported and locally blended in order to deposit fat as a connection between beauty and propensity. The objectives of the study were to evaluate the epidemiological and socio-demographic characteristics of GCs misuse among reproductive women in the South of Iraq. Methods: a cross-sectional study was conducted on 251 reproductive-aged women who were misusing GCs for any cause and attending Thi-Qar Specialized Diabetes, Endocrine and Metabolism Center (TDEMC) in Nasiriya City. They were evaluated for demographic characteristics, medical and social histories, and then examined carefully for any signs of GCs misuse. Results: The mean ages of women were 33.21±8.6 years, BMI 30.68±7.3 Kg/m², and 208 (82.9%) women were either overweight or obese. More than half (51.3%) of the women were misusing two or more forma of GCs and one quarter (26.7%) of them were misusing tablets. The types of GCs misused were presented as 77.7% dexamethasone, 19.5% prednisolone, 22.3% hydrocortisone, 21.1% betamethasone, 17.5% local GCs types, and 13.5% Inhaler GCs types. The major source of GCs misuse was pharmacy 201 (80.1%) and 18 (7.2%) from street vendors. Approximately, all women had many features of GCs-induced adverse effects and there were many misconceptions about their safety like 41.8% thought that using GCs was safe, and 45.8% did not really feel guilty about using those medications. About 90 of them (35.9%) were still misusing drugs during the time of meeting, 53 (21.1%) reported that physicians recommended them at the first time for using glucocorticoids and the majority 198 (78.9%) were misusing GCs by themselves, friends, or first-degree family to become beautiful or marry. Conclusions: The relatively high rate of misuse of these drugs can be attributed to the lack of awareness of their chronic adverse effects, their widespread availability at pharmacies, plus their dramatic and quick response. Therefore, educational programs have to be implemented to inform the public about the adverse effects of GCs and the problems of misuse of drugs.
{"title":"Glucocorticoids (GCs) are widely accessible over-the-counter (OTC), liberally recommended by locals medical practitioner, and freEpidemiological and Socio-demographic Characters of Glucocorticoids Misuse among Premenopausal Women in Thi-Qar, Southern Iraq","authors":"Asia Hameed Saddam, Majid Abdulwahab Maatook, Mahmood Thamer Altemimi","doi":"10.32792/utq/utjsci/v10i1(si).966","DOIUrl":"https://doi.org/10.32792/utq/utjsci/v10i1(si).966","url":null,"abstract":"Glucocorticoids (GCs) are widely accessible over-the-counter (OTC), liberally recommended by locals medical practitioner, and frequently misused by women for the purpose of treatment of skin conditions, joint pains, febrile illnesses and asthma. Unfortunately, ladies misuse a lot of over-the-counter GCs and glucocorticoids containing cosmetic creams, both imported and locally blended in order to deposit fat as a connection between beauty and propensity. The objectives of the study were to evaluate the epidemiological and socio-demographic characteristics of GCs misuse among reproductive women in the South of Iraq. \u0000Methods: a cross-sectional study was conducted on 251 reproductive-aged women who were misusing GCs for any cause and attending Thi-Qar Specialized Diabetes, Endocrine and Metabolism Center (TDEMC) in Nasiriya City. They were evaluated for demographic characteristics, medical and social histories, and then examined carefully for any signs of GCs misuse. \u0000Results: The mean ages of women were 33.21±8.6 years, BMI 30.68±7.3 Kg/m², and 208 (82.9%) women were either overweight or obese. More than half (51.3%) of the women were misusing two or more forma of GCs and one quarter (26.7%) of them were misusing tablets. The types of GCs misused were presented as 77.7% dexamethasone, 19.5% prednisolone, 22.3% hydrocortisone, 21.1% betamethasone, 17.5% local GCs types, and 13.5% Inhaler GCs types. The major source of GCs misuse was pharmacy 201 (80.1%) and 18 (7.2%) from street vendors. Approximately, all women had many features of GCs-induced adverse effects and there were many misconceptions about their safety like 41.8% thought that using GCs was safe, and 45.8% did not really feel guilty about using those medications. About 90 of them (35.9%) were still misusing drugs during the time of meeting, 53 (21.1%) reported that physicians recommended them at the first time for using glucocorticoids and the majority 198 (78.9%) were misusing GCs by themselves, friends, or first-degree family to become beautiful or marry. \u0000Conclusions: The relatively high rate of misuse of these drugs can be attributed to the lack of awareness of their chronic adverse effects, their widespread availability at pharmacies, plus their dramatic and quick response. Therefore, educational programs have to be implemented to inform the public about the adverse effects of GCs and the problems of misuse of drugs. \u0000 ","PeriodicalId":23432,"journal":{"name":"University of Thi-Qar Journal of Science","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84741259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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