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Valuation of the Alzheimer’s Disease 5 Dimensions Instrument: A Discrete Choice Experiment With Life Duration in Chile 评估阿尔茨海默病的5维仪器：一个离散选择实验与寿命在智利
IF 1.4 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-11-01 Epub Date: 2025-06-17 DOI: 10.1016/j.vhri.2025.101148
Daniel A. Araya-Ríos MA , Kim-Huong Nguyen PhD , Tracy A. Comans PhD , Dominic Trépel PhD

Objectives

To estimate utility weights for the Alzheimer’s Disease 5 Dimensions (AD-5D) instrument in the Chilean population to obtain health utilities.

Methods

A panel sample of the Chilean population was recruited online to complete a discrete choice experiment with time duration. Weights were built based on region of residence, gender, age, and educational level. The experimental design comprised 20 blocks, each composed of 12 choice sets. In each choice set, participants compared 2 health states described by the 5 AD-5D dimensions and the life duration. A multinomial logit model was used to analyze the data, and preference parameters were anchored to the health utility scale to produce utility weights that can be used to estimate quality-adjusted life years.

Results

The study included 1895 participants who completed the discrete choice tasks. The weighted sample showed that the respondents were more educated than the general population of Chile. However, other characteristics were comparable. The Physical Health dimension had the greatest impact on utility, followed by Living Situation, Mood, Memory, and Ability to do things for fun. The health utility values ranged from 1 to −1.09, with 23% of health states having negative utilities.

Conclusions

To our knowledge, this study provides the first AD-5D utility weights for the Chilean population to be used in trials, healthcare, and economic evaluations of dementia-related interventions. Because the AD-5D instrument is based on the Quality of Life Alzheimer’s Disease Instrument, the estimated health utility weights allow estimation of quality-adjusted life years whenever the Quality of Life Alzheimer’s Disease is available.
目的估计阿尔茨海默病5维度（AD-5D）仪器在智利人群中的效用权重，以获得健康效用。方法在网上招募智利人口的一个小组样本，完成一个有时间持续的离散选择实验。权重是根据居住地区、性别、年龄和教育水平建立的。实验设计由20个模块组成，每个模块由12个选择集组成。在每个选择集中，参与者比较由5个AD-5D维度和寿命描述的2种健康状态。使用多项logit模型对数据进行分析，并将偏好参数固定在健康效用量表上，以产生可用于估计质量调整寿命年的效用权重。研究包括1895名完成离散选择任务的参与者。加权样本显示，受访者的受教育程度高于智利的一般人口。然而，其他特征具有可比性。“身体健康”维度对效用的影响最大，其次是生活状况、情绪、记忆和做事的能力。健康状况效用值的范围从1到- 1.09，其中23%的健康状况具有负效用。据我们所知，本研究首次为智利人群提供了AD-5D效用权重，可用于痴呆相关干预措施的试验、医疗保健和经济评估。因为AD-5D仪器是基于阿尔茨海默病生活质量仪器，估计的健康效用权重允许在阿尔茨海默病生活质量可用时估计质量调整生命年。
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引用次数: 0
Psychometric Validation of EQ-5D-5L in Individuals With Chronic Spinal Cord Injury in China 中国慢性脊髓损伤患者EQ-5D-5L的心理测量验证
IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-11-01 Epub Date: 2025-08-11 DOI: 10.1016/j.vhri.2025.101164
Haixia Xie BSMHE , Qi Zhang PhD , Rong Jin BDS , Jianhui He MPA , Xinxing Hu MPA , Yixuan Zhang MPH , Xiaoping Shao BSN , Xiaohong Li PhD , Hua Zhai MBA , Fengshui Chang PhD

Objectives

The EQ-5D is a brief measure for assessing health-related quality of life (HRQoL), but chronic spinal cord injury (CSCI) related psychometric evaluation of the EQ-5D-5L has not been explored. We conducted a validation study on the Chinese version of the EQ-5D-5L for individuals with CSCI in China.

Methods

A cross-sectional study was conducted in the Shanghai Sunshine Rehabilitation Center. The floor and ceiling effects, internal consistency, test and retest reliability, discriminatory power (only for EQ-5D-5L), convergent validity (using Spearman correlation coefficients), and known-group validity of the EQ-5D-5L and visual analog scale (VAS) were analyzed.

Results

A total of 271 individuals with CSCI were included in analysis. The mean (SD) utility and VAS scores were 0.46 (0.31) and 66.8 (20.3), respectively, and they showed no floor or ceiling effects. The EQ-5D-5L demonstrated acceptable internal consistency (Cronbach’s α = 0.84) and test-retest reliability. The average Shannon index (H′) and Shannon Evenness index (J′) of the EQ-5D-5L were 2.01 and 0.86, respectively. Satisfactory convergent validity was shown by the correlation analysis among the 5 EQ-5D-5L dimensions, EQ-5D-5L utility, EQ-VAS, the World Health Organization quality-of-life scale brief version, 7-item generalized anxiety disorder scale (GAD-7), 9-item patient health questionnaire (PHQ-9), and General Self-Efficacy Scale (GSES). Utility and VAS scores showed the predicted pattern among a priori known groups, with effect sizes ranging from 0.06 to 0.72 for the EQ-5D-5L, and 0.02 to 1.08 for the VAS.

Conclusions

The EQ-5D-5L is a reliable and valid measure of HRQoL for individuals with CSCI in China.
目的EQ-5D是一种评估健康相关生活质量（HRQoL）的简单测量方法，但尚未对EQ-5D- 5l进行慢性脊髓损伤（CSCI）相关的心理测量评估。我们对中国CSCI患者的中文版EQ-5D-5L进行了验证性研究。方法在上海市阳光康复中心进行横断面研究。分析了EQ-5D-5L和视觉模拟量表（VAS）的下限和上限效应、内部一致性、测试和重测信度、区分力（仅针对EQ-5D-5L）、收敛效度（采用Spearman相关系数）和已知组效度。结果共纳入271例CSCI患者。平均（SD）效用和VAS评分分别为0.46（0.31）和66.8(20.3)，没有下限或上限效应。EQ-5D-5L具有良好的内部一致性（Cronbach’s α = 0.84）和重测信度。EQ-5D-5L的平均香农指数（H′）和香农均匀度指数（J′）分别为2.01和0.86。EQ-5D-5L 5个维度、EQ-5D-5L效用、EQ-VAS、世界卫生组织生活质量量表简易版、7项广泛性焦虑障碍量表（GAD-7）、9项患者健康问卷（PHQ-9）和一般自我效能量表（GSES）的相关分析显示，趋同效度较好。效用和VAS评分在先验已知组中显示预测模式，EQ-5D-5L的效应值范围为0.06至0.72，VAS的效应值范围为0.02至1.08。结论EQ-5D-5L是中国CSCI患者HRQoL的一种可靠有效的测量方法。
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引用次数: 0
RWD91 DIRECT MEDICAL COSTS OF NASOPHARYNGEAL CARCINOMA IN INDONESIA: A HEALTHCARE PAYER PERSPECTIVE Rwd91印度尼西亚鼻咽癌的直接医疗费用：保健付款人的观点
IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-10-01 Epub Date: 2025-10-31 DOI: 10.1016/j.vhri.2025.101320
Junice Ng MD , Erna Kristin MD , Cosphiadi Irawan MD , Susanna Hutajulu MD , Yussy Afriani Dewi MD , Gregorius Ben Prajogi MD , Lucia Rizka Andalucia MD , Donni Hendrawan MD , Sudi Indra Jaya MD , Royasia Ramadani MD , See-Hwee Yeo PhD , Shikha Dhawan MD
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引用次数: 0
RWD171 RESEARCH ON STAKEHOLDER COLLABORATION MECHANISM FOR MEDICAL DATA SHARING: A THREE-PARTY EVOLUTIONARY GAME ANALYSIS 医疗数据共享的利益相关者协作机制研究：三方演化博弈分析
IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-10-01 Epub Date: 2025-10-31 DOI: 10.1016/j.vhri.2025.101548
Menglei Kong PhD , Xinchang Liu PhD , Wai-kit Ming MPH, PhD, MD
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引用次数: 0
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IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-10-01 Epub Date: 2025-10-31 DOI: 10.1016/j.vhri.2025.101537
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引用次数: 0
RWD9 A TASK-ORIENTED MULTI-SOURCE HETEROGENEOUS DATA FUSION FRAMEWORK FOR HEALTHCARE AND ELDERLY CARE INTEGRATION Rwd9是面向任务的多源异构数据融合框架，用于医疗保健和老年护理集成
IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-10-01 Epub Date: 2025-10-31 DOI: 10.1016/j.vhri.2025.101188
Menglei Kong PhD, Wai-kit Ming MPH, PhD, MD, Xinchang Liu PhD
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引用次数: 0
RWD48 THE IMPACT OF ENTERAL NUTRITION ON THE SHORT-TERM AND SURVIVAL OUTCOMES OF LUNG CANCER AND BREAST CANCER PATIENTS UNDERGOING MEDICAL TREATMENT 肠内营养对接受药物治疗的肺癌和乳腺癌患者的短期和生存结果的影响
IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-10-01 Epub Date: 2025-10-31 DOI: 10.1016/j.vhri.2025.101246
Qian Zhuang master
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引用次数: 0
RWD54 EXPLORATORY DESCRIPTIVE ANALYSIS OF PERIOPERATIVE STOMA CARE AND OUTCOMES: COMPARING JAPAN TO GLOBAL AVERAGES Rwd54对围手术期造口护理和结果的探索性描述性分析：比较日本与全球平均水平
IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-10-01 Epub Date: 2025-10-31 DOI: 10.1016/j.vhri.2025.101252
Xiao Wen Luah M.Sc., B.Sc Pharm , Yasumi Matsubara PhD , Sumako Naito B.Sc , Naoko Nakamura MSN, MPH , Xiao Wei Fei PhD , Henrik Koblauch PhD
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引用次数: 0
RWD198 ESTIMATING THRESHOLD FOR GOOD QUALITY OF LIFE IN AGED CARE RESIDENTS: ANCHOR-BASED CUT-OFF FOR THE QUALITY OF LIFE-AGED CARE CONSUMERS INSTRUMENT Rwd198老年居民良好生活质量估计阈值：基于锚点的生活质量截断老年护理消费者工具
IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-10-01 Epub Date: 2025-10-31 DOI: 10.1016/j.vhri.2025.101265
Jyoti Khadka PhD , Jia Song PhD , Rachel Milte PhD , Julie Ratcliffe PhD
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引用次数: 0
RWD21 PHARMACEUTICAL APPROACHES TO ENHANCING RWE DATA COLLECTED IN NON-INTERVENTIONAL STUDIES Rwd21加强非介入性研究中收集的rwe数据的药物方法
IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Value in health regional issues
Pub Date : 2025-10-01 Epub Date: 2025-10-31 DOI: 10.1016/j.vhri.2025.101199
SOO H. LEE M.PH., Min-Taek Lee Ph.D., Bo-Ram Park Ph.D., Seung-Hee Jeong Ph.D.
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引用次数: 0
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Value in health regional issues
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