{"title":"Nursing Care of a Patient with Arteriovenouz Malformation According to Orem’s Self-Care Deficit Nursinde Theory: Case Report","authors":"A. Özdemİr, Ş. İ. Güner, A. M. Geyik","doi":"10.5505/vtd.2022.01212","DOIUrl":"https://doi.org/10.5505/vtd.2022.01212","url":null,"abstract":"","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"126 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78179423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Irfan Binici, M. Karahocagil, M. Sünnetçioğlu, M. Parlak
{"title":"The Surveyans of Colonisation of Vancomycin Resistant Enterococci and Investigation Antibiotic Susceptibility and Risk Factors","authors":"Irfan Binici, M. Karahocagil, M. Sünnetçioğlu, M. Parlak","doi":"10.5505/vtd.2022.26428","DOIUrl":"https://doi.org/10.5505/vtd.2022.26428","url":null,"abstract":"","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88708146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ş. Külahçıoğlu, Kadir Bıyıklı, D. Çeneli, S. Tanyeri, B. Kültürsay, B. Keskin, Okan Korun, E. Cakmak, Enver Yücel, A. Karagoz, I. Tanboğa, C. Kaymaz
{"title":"Evaluation of the Relationship Between Eosinophil to Monocyte Ratio and Ieft Ventricle Ejection Fraction in Patients With Acute Coronary Syndrome","authors":"Ş. Külahçıoğlu, Kadir Bıyıklı, D. Çeneli, S. Tanyeri, B. Kültürsay, B. Keskin, Okan Korun, E. Cakmak, Enver Yücel, A. Karagoz, I. Tanboğa, C. Kaymaz","doi":"10.5505/vtd.2022.18199","DOIUrl":"https://doi.org/10.5505/vtd.2022.18199","url":null,"abstract":"","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72838213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: This study was planned to compare the quality of life and personal traits in menopausal women. Methods: The population of the study comprised women who applied to Family Health Centers (FHC) in the city center of Bingol (n=157). A survey form, which was prepared by the researcher as a result of evaluating the relevant literature and comprised three sections, was applied to the women who met the inclusion criteria. The first section of the survey consisted of a questionnaire questionin g the participants’ s ocio-demographic characteristics, obstetrical, gynecological, chronic disease history, information about the menopausal period and general health behaviors. The second section consisted of the “Menopause -Specific Quality of Life Questi onnaire (MSQLQ)” and the third section consisted of the Cervantes Personality Scale (CPS). Results: There was a positive significant correlation between the scores, obtained by the women who participated in the study, from the CPS emotional stability/neuroticism subscale and the MSQLQ scores, whereas there was a negative significant correlation between their sincerity/insincerity scores and MSQLQ scores. There was no statistically significant correlation between the extroversion/introversion subscale and MSQLQ symptoms. Conclusions: It was determined that the women had no adequate knowledge of this period which comprises nearly one third of their life, there were deficiencies in coping with menopausal symptoms and the quality of life of the women in the menopausal period was not at the required level. In the personality development phases, women should be encouraged for positive, emotionally stable and extrovert personality development and to use of healthy defense mechanisms.
{"title":"A Comparison of the Quality of life and Personal Traits in Menopausal Women","authors":"Aliye Bulut, Handan Özcan, E. Arbağ","doi":"10.5505/vtd.2022.65148","DOIUrl":"https://doi.org/10.5505/vtd.2022.65148","url":null,"abstract":"Introduction: This study was planned to compare the quality of life and personal traits in menopausal women. Methods: The population of the study comprised women who applied to Family Health Centers (FHC) in the city center of Bingol (n=157). A survey form, which was prepared by the researcher as a result of evaluating the relevant literature and comprised three sections, was applied to the women who met the inclusion criteria. The first section of the survey consisted of a questionnaire questionin g the participants’ s ocio-demographic characteristics, obstetrical, gynecological, chronic disease history, information about the menopausal period and general health behaviors. The second section consisted of the “Menopause -Specific Quality of Life Questi onnaire (MSQLQ)” and the third section consisted of the Cervantes Personality Scale (CPS). Results: There was a positive significant correlation between the scores, obtained by the women who participated in the study, from the CPS emotional stability/neuroticism subscale and the MSQLQ scores, whereas there was a negative significant correlation between their sincerity/insincerity scores and MSQLQ scores. There was no statistically significant correlation between the extroversion/introversion subscale and MSQLQ symptoms. Conclusions: It was determined that the women had no adequate knowledge of this period which comprises nearly one third of their life, there were deficiencies in coping with menopausal symptoms and the quality of life of the women in the menopausal period was not at the required level. In the personality development phases, women should be encouraged for positive, emotionally stable and extrovert personality development and to use of healthy defense mechanisms.","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89758557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognostic Significance of Ratio of Metastatic Lymph Nodes in Colorectal Cancer Patients Treated with Curative Resection","authors":"K. Gülben, O. Uyar, B. Öndeş","doi":"10.5505/vtd.2022.24855","DOIUrl":"https://doi.org/10.5505/vtd.2022.24855","url":null,"abstract":"","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82552497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lysosomes are organelles that break down damaged components or structures that have completed their task in the cell by the hydrolytic enzymes they contain and take part in the last step of the autophagic pathway. Autophagy, an evolutionarily conserved lysosomal pathway, is activated under stress conditions such as amino acid starvation, accumulation of unfolded proteins, or viral infection. The main task of autophagy is to remove damaged proteins, organelles and microorganisms that constitute the source of infection. During this degradation mechanism, autophagosomes are formed as a result of the interaction of lysosomes and autophagic vesicles carrying damaged proteins, and this formation is tightly controlled by cellular mechanisms. Damage during this interaction can disrupt cellular homeostasis and interfere with the survival of the organism. Lysosomal Storage Diseases (LDH) is one of the most common human genetic diseases that develop because of mutations on genes encoding lysosomal enzymes. To date, more than 70 LDHs have been identified. LDH is mainly caused by functional disorders of enzymes or lysosome-associated proteins in lysosomes. These disorders may cause undigested macromolecules to accumulate in the cells, compromising the proper functioning of the organs in which they are located. LDH can cause many systemic damages, especially in the nervous system, skeletal system, and reticuloendothelial system, especially in the early stages of the disease. Modulation and reactivation of autophagy is considered a new therapeutic approach for LDH. In this review, the general mechanisms of the relationship between lysosomal storage diseases and autophagy were evaluated together with treatment approaches.
{"title":"Relationship of Lysosomal Storage Diseases (LSD) with Autophagy","authors":"S. Keskin, I. Alkac, B. Çerçi","doi":"10.5505/vtd.2022.95776","DOIUrl":"https://doi.org/10.5505/vtd.2022.95776","url":null,"abstract":"Lysosomes are organelles that break down damaged components or structures that have completed their task in the cell by the hydrolytic enzymes they contain and take part in the last step of the autophagic pathway. Autophagy, an evolutionarily conserved lysosomal pathway, is activated under stress conditions such as amino acid starvation, accumulation of unfolded proteins, or viral infection. The main task of autophagy is to remove damaged proteins, organelles and microorganisms that constitute the source of infection. During this degradation mechanism, autophagosomes are formed as a result of the interaction of lysosomes and autophagic vesicles carrying damaged proteins, and this formation is tightly controlled by cellular mechanisms. Damage during this interaction can disrupt cellular homeostasis and interfere with the survival of the organism. Lysosomal Storage Diseases (LDH) is one of the most common human genetic diseases that develop because of mutations on genes encoding lysosomal enzymes. To date, more than 70 LDHs have been identified. LDH is mainly caused by functional disorders of enzymes or lysosome-associated proteins in lysosomes. These disorders may cause undigested macromolecules to accumulate in the cells, compromising the proper functioning of the organs in which they are located. LDH can cause many systemic damages, especially in the nervous system, skeletal system, and reticuloendothelial system, especially in the early stages of the disease. Modulation and reactivation of autophagy is considered a new therapeutic approach for LDH. In this review, the general mechanisms of the relationship between lysosomal storage diseases and autophagy were evaluated together with treatment approaches.","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"117 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79467044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Duran Topak, Mustafa Özdemir, F. Doğar, Kadir İsmail Dere, Halil Mutlu, Ökkeş Bilal
{"title":"Can Titanium Elastic Nails be the First Treatment Choice in Pediatric Femoral Shaft Fractures?","authors":"Duran Topak, Mustafa Özdemir, F. Doğar, Kadir İsmail Dere, Halil Mutlu, Ökkeş Bilal","doi":"10.5505/vtd.2022.34538","DOIUrl":"https://doi.org/10.5505/vtd.2022.34538","url":null,"abstract":"","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81095190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fahr Syndrome Diagnosed by the First Attack Psychosis: A Case Report","authors":"Yavuz Selim Atan, U. Kırlı","doi":"10.5505/vtd.2022.35682","DOIUrl":"https://doi.org/10.5505/vtd.2022.35682","url":null,"abstract":"","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"132 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87907373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gozde Sahin, T. Duran, Serkan Küççüktürk, N. Koçak, Denizhan Bayramoğlu, A. Kebapçılar, Ç. Çelik
{"title":"Apoptotic Effect Of Neferine On Cervical Cancer Cells (HeLa)","authors":"Gozde Sahin, T. Duran, Serkan Küççüktürk, N. Koçak, Denizhan Bayramoğlu, A. Kebapçılar, Ç. Çelik","doi":"10.5505/vtd.2022.87094","DOIUrl":"https://doi.org/10.5505/vtd.2022.87094","url":null,"abstract":"","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90536067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can Ultrasonography-Guided Aspiration be an Alternative to Surgery in Wrist Ganglion Cysts?","authors":"Ensar Türko, Sinan Oguzkaya","doi":"10.5505/vtd.2022.77642","DOIUrl":"https://doi.org/10.5505/vtd.2022.77642","url":null,"abstract":"","PeriodicalId":23509,"journal":{"name":"Van Medical Journal","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77423456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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