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The Worth of Ionized Calcium Levels Calculated by Zeisler, Butler and Hanna Methods in Diagnosis of Hypocalcemia Zeisler、Butler和Hanna法计算的钙离子水平在低钙血症诊断中的价值
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.42744
Tuba Batur, Halil İbrahim Akbay, E. Çokluk
Introduction: It was aimed to examine the diagnostic performance of the ionized calcium levels calculated by the Zeisler, Butler and Hanna method on the evaluation of hypocalcemia. Materials and Methods: Whole blood ionized calcium and serum total calcium levels of 500 individuals aged between 20-60 years were retrospectively screened. Individuals were divided into hypoalbuminemia and normoalbuminemia groups according to their serum albumin concentrations. In these groups, the diagnostic performance of total calcium and ionized calcium concentrations calculated by Zeisler,Butler and Hanna methods in terms of hypocalcemia were examined. While determining hypocalcemia, ionized calcium level was accepted as a reference.The difference and correlation between directly measured ionized calcium and calculated ionized calcium were analyzed by Wilcoxon signed ranks and Spearman correlation analysis. Results: The ionized calcium levels calculated by the Zeisler,Butler, Hanna methods were higher than the directly measured ionized calcium level. The method with the highest sensitivity and accuracy in terms of hypocalcemia was the Zeisler method.However, the specificity and negative predictive values were low.There was no correlation between directly measured ionized calcium and calculated ionized calcium levels in the hypoalbuminemia group. A significant correlation was observed between ionized calcium and calcium levels calculated by the Zeisler and Hanna methods in the normoalbuminemia group,but this correlation was low. No correlation was observed between ionized calcium and calcium calculated by Butler's method. Conclusion : The results of the study limit the use of the Zeisler,Butler and Hanna methods in estimating ionized calcium. We believe that it would not be reliable to comment on the level of ionized calcium with these methods.
前言:本研究旨在探讨Zeisler, Butler和Hanna法计算的离子钙水平对低钙血症的诊断价值。材料与方法:回顾性筛选500例20 ~ 60岁人群的全血离子钙和血清总钙水平。根据血清白蛋白浓度分为低白蛋白血症组和正常白蛋白血症组。在这些组中,检查了Zeisler,Butler和Hanna方法计算的总钙和电离钙浓度在低钙血症方面的诊断性能。在测定低钙血症时,离子钙水平可作为参考。采用Wilcoxon符号秩和Spearman相关分析,分析直接测得的离子钙与计算得到的离子钙的差异和相关性。结果:Zeisler、Butler、Hanna法计算的离子钙水平高于直接测量的离子钙水平。Zeisler法是测定低血钙的灵敏度和准确度最高的方法。然而,特异性和阴性预测值较低。在低白蛋白血症组中,直接测量的电离钙和计算的电离钙水平之间没有相关性。在正常白蛋白血症组中,观察到离子钙与Zeisler和Hanna方法计算的钙水平之间存在显著相关性,但这种相关性较低。电离钙与巴特勒方法计算的钙之间没有相关性。结论:本研究结果限制了Zeisler、Butler和Hanna方法在估计电离钙方面的应用。我们认为,用这些方法评价电离钙的水平是不可靠的。
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引用次数: 0
Effects of Lower Urinary Truct Symptoms on Quality of Life and Complementary Treatments in Multiple Sclerosis 下尿路症状对多发性硬化症患者生活质量的影响及辅助治疗
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.36776
Ş. Özen, Ülkü Polat
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引用次数: 0
The Probable Suspect in the Prediction of Relapse in Acute Leukemia: Thrombocytopenia 预测急性白血病复发的可能因素:血小板减少症
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.17092
İpek Dokurel Çetin, N. Özdemir, T. Celkan, Sarper Erdogan, H. Apak
Objective: Relapse is not common in patients with acute leukemia in childhood, however it is a serious complication with high mortality rate . We aimed to predict relapse among pediatric acute leukemia patients in remission by using complete blood parameters which are used routinely in clinical practice. Materials and Methods : The data of 279 children diagnosed with acute leukemia in our clinic over a 20-year period were retrospectively reviewed. Fourty two children relapsed and 37 children non-relapsed acute leukemia cases, all of whose data were available, were included in the study. Blood count parameters and physical examination findings at the time of diagnosis and during the follow-up were evaluated retrospectively in all patients. Mann-Whitney U and T-test were used for comparison of numerical variables. Chi-square test was used to compare categorical variables. Results: In the relapse group; twenty-four children were diagnosed with B-cell ALL, 10 children with T-cell ALL, and eight children with AML. In non-relapse group; 26 children had B-cell ALL, 10 children were diagnosed with T-cell and one child had AML. Thrombocytopenia was observed in 24 patients for the relapse group, compared to nine children in non-relapse group. After remission, the risk of relapse was significantly higher in patients with thrombocytopenia than in patients without thrombocytopenia among both groups. During the remission period, relapse was observed in all patients with thrombocytopenia lasting for an average of 3.86 weeks. Conclusion: Thrombocytopenia during the remission period of pediatric acute leukemia patients can be explained primarily by the effect of chemotherapeutic drugs used in treatment and possible infections on the bone marrow. We demonstrated that the presence of thrombocytopenia which develops after the remission period and lasts longer than three weeks can be used as an easy-to-access blood parameter in the prediction of relapse.
目的:儿童期急性白血病的复发并不常见,但它是一种严重的并发症,死亡率高。我们的目的是通过使用临床常规使用的全血参数来预测缓解期儿科急性白血病患者的复发。材料与方法:回顾性分析我院近20年来279例急性白血病患儿的资料。42例复发儿童和37例非复发儿童急性白血病病例纳入研究,所有数据均可获得。对所有患者在诊断时和随访期间的血细胞计数参数和体格检查结果进行回顾性评估。数值变量比较采用Mann-Whitney U检验和t检验。分类变量比较采用卡方检验。结果:复发组;24名儿童被诊断为b细胞ALL, 10名儿童被诊断为t细胞ALL, 8名儿童被诊断为急性髓性白血病。非复发组;26名儿童患有b细胞性ALL, 10名儿童被诊断为t细胞,1名儿童患有急性髓性白血病。复发组有24例患者出现血小板减少,而非复发组只有9例。缓解后,两组中有血小板减少的患者复发的风险明显高于无血小板减少的患者。在缓解期,所有血小板减少患者的复发平均持续3.86周。结论:小儿急性白血病缓解期血小板减少主要与化疗药物的疗效及可能的骨髓感染有关。我们证明,在缓解期后出现的血小板减少症持续时间超过三周,可以作为预测复发的一个容易获得的血液参数。
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引用次数: 0
Code Blue, Is It Really Blue? 蓝色警报,真的是蓝色吗?
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.67934
M. Baytar, Çağdaş Baytar
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引用次数: 0
The Role of the Mediterranean Diet in the Prevention of Deep Vein Thrombosis 地中海饮食在预防深静脉血栓中的作用
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.56255
M. Ekim, H. Ekim, M. Tuncer
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引用次数: 0
The Relatıonshıp Between Pet Ct And Tumor Features In Patıents Wıth Breast Cancer Patıents Wıth乳腺癌Pet Ct与肿瘤特征Relatıonshıp的关系
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.74340
Y. Sezgin, Oğur Karhan, S. Ileri, S. Ebinç, E. Bilen, M. Urun, Halis Yerlikaya
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引用次数: 0
Nursing Care of a Patient Diagnosed with Hemophilia A Undergoing Coronary Artery Bypass Graft Surgery: A Case Report 1例a型血友病患者行冠状动脉搭桥手术的护理
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.58998
Tuğba Albayram, Ş. İ. Güner
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引用次数: 0
Professional Attitudes of Third-Year Medical Students: A Cross-Sectional Study 三年级医学生职业态度的横断面研究
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.21456
Esra Çınar Tanrıverdi
Introduction: Medical professionalism is one of the areas of competence in undergraduate and postgraduate medical education. In this study, we aimed to determine the medical professionalism attitudes of third-year medical students and to investigate the effect of gender, reason for preference, and presence of a doctor in the family on these attitudes. Materials and Methods: A cross-sectional study was carried out with 331 third-graders who volunteered. Data was collected in 17.02.2020. As data collection tools, the Penn State School of Medicine (PSCOM) professionalism questionnaire-student form and a short sociodemographic information form were used. Data were analyzed using the SPSS 20.0 software (SPSS Inc., Chicago, IL, USA) program. Results: The average age of stu dents was 21.45±2.00, and 168 (50.8%) of them were female. Average attitude scores are found as, for accountability 30.29 ± 4.19 (7-35), enrichment 24.88 ± 3.78 (6-30), equity 18.26 ± 2.12 (4-20), honor and integrity 36.37 ± 3.87 (8-40), altruism 13.11 ± 1.90 (3-15), duty 21.92 ± 2.80 (5-25), respect 9.05 ± 1.25 (2-10). Professional attitude scores of female students were higher than men's, students who chose the medical school for their ideal and to help people had significantly higher scores than students who preferred it for other reasons. No significant difference was found between attitude scores of students with and without the presence of a doctor in their family. Conclusion: Third-year medical students have a positive attitude towards professionalism. While gender and medical school preference were effective on these attitudes, the presence of doctors in the family was not found to be effective.
医学专业精神是本科和研究生医学教育的能力领域之一。在本研究中,我们旨在确定医三学生的医学专业态度,并探讨性别、偏好原因和家庭中是否有医生对这些态度的影响。材料与方法:对331名自愿参加的三年级学生进行横断面研究。数据于2020年2月17日收集。作为数据收集工具,使用了宾夕法尼亚州立医学院(PSCOM)专业调查问卷-学生表格和简短的社会人口信息表格。数据分析采用SPSS 20.0软件(SPSS Inc., Chicago, IL, USA)程序。结果:学生平均年龄(21.45±2.00)岁,女性168人(50.8%)。平均态度得分为:问责30.29±4.19(7-35),充实24.88±3.78(6-30),公平18.26±2.12(4-20),荣誉和正直36.37±3.87(8-40),利他13.11±1.90(3-15),责任21.92±2.80(5-25),尊重9.05±1.25(2-10)。女学生的职业态度得分高于男学生,以理想和助人为目的选择医学院的学生的职业态度得分明显高于其他原因选择医学院的学生。家庭中有医生陪伴与没有医生陪伴的学生态度得分无显著差异。结论:医三学生对职业素养持积极态度。虽然性别和医学院偏好对这些态度有影响,但发现家庭中是否有医生没有影响。
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引用次数: 3
Approaches to Dyslipidemia Treatments of Doctors of Family Medicine Discipline in Different Steps 家庭医学医生分阶段治疗血脂异常的探讨
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.53896
Harun Karahan, H. Mutlu, H. H. Mutlu, S. Öztürk
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引用次数: 1
Comparison of the Pathological Findings by Endorectal Ultrasonography in Pre-operative Staging of Rectum Cancer 直肠内超声对直肠癌术前分期病理表现的比较
Pub Date : 2022-01-01 DOI: 10.5505/vtd.2022.03083
Muharrem Oner, N. Hacım
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引用次数: 0
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Van Medical Journal
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