Tran Van Loc, Nguyen The Anh, T. T. Thao, Tran Van Chien
Phytochemical components of the aerial parts of Andrographis paniculata collected in Bac Giang province was investigated. Fourteen compounds, including seven labdane diterpene lactones [andrographolide (1), 3,19‐isopropylidene‐andrographolide (2), andropanolide (4), 14‐deoxy‐12‐hydroxyandrographolide (5), 14‐dehydroxyandrographolide‐12‐sulfonic acid (6), 14‐deoxy‐11,12‐didehydroandrographolide (8), 14‐deoxy‐14,15‐didehydroandrographolide (11)], together with four diterpene glycosides [andrographiside (3), neoandrographolide (7), andropanoside (9), 14‐deoxy‐11,12‐didehydroandrographiside (10)], and three iridoid glycosides [harpagide (12), 6‐epi‐8‐O‐acetyl‐harpagide (13), procumbide (14)] were isolated. Among these, 14‐dehydroxyandrographolide‐12‐sulfonic acid (6) was isolated for the first time from natural resource, and for the first‐time harpagide (12) was isolated from Andrographis paniculata species. The detailed structures of isolated compounds were elucidated by analyses of 1D and 2D NMR spectra and compared to the published data. Diterpene lactones, 1–2, 5 and 10–11, were evaluated for their anti‐inflammatory inhibition on LPS‐triggered inflammatory responses in RAW 264.7 cells, in which 1 and 2 showed significantly potent inhibition on NO production with IC50 values of 1.3 and 0.34 µm, respectively.
{"title":"Isolation and anti‐inflammatory evaluation of diterpene lactones from Andrographis paniculata collected in Bac Giang province, Vietnam","authors":"Tran Van Loc, Nguyen The Anh, T. T. Thao, Tran Van Chien","doi":"10.1002/vjch.202300281","DOIUrl":"https://doi.org/10.1002/vjch.202300281","url":null,"abstract":"Phytochemical components of the aerial parts of Andrographis paniculata collected in Bac Giang province was investigated. Fourteen compounds, including seven labdane diterpene lactones [andrographolide (1), 3,19‐isopropylidene‐andrographolide (2), andropanolide (4), 14‐deoxy‐12‐hydroxyandrographolide (5), 14‐dehydroxyandrographolide‐12‐sulfonic acid (6), 14‐deoxy‐11,12‐didehydroandrographolide (8), 14‐deoxy‐14,15‐didehydroandrographolide (11)], together with four diterpene glycosides [andrographiside (3), neoandrographolide (7), andropanoside (9), 14‐deoxy‐11,12‐didehydroandrographiside (10)], and three iridoid glycosides [harpagide (12), 6‐epi‐8‐O‐acetyl‐harpagide (13), procumbide (14)] were isolated. Among these, 14‐dehydroxyandrographolide‐12‐sulfonic acid (6) was isolated for the first time from natural resource, and for the first‐time harpagide (12) was isolated from Andrographis paniculata species. The detailed structures of isolated compounds were elucidated by analyses of 1D and 2D NMR spectra and compared to the published data. Diterpene lactones, 1–2, 5 and 10–11, were evaluated for their anti‐inflammatory inhibition on LPS‐triggered inflammatory responses in RAW 264.7 cells, in which 1 and 2 showed significantly potent inhibition on NO production with IC50 values of 1.3 and 0.34 µm, respectively.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140244456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. T. Do, Truong Giang Ho, Hong Thai Giang, Quang Ngan Pham, Duc Toan Nguyen, T. Nghiem, Trung Hieu Nguyen, Minh Tan Man
Tungsten oxide (WO3) nanoplates were synthesized by a simple chemical precipitation technique. These nanoplates were decorated by Au nanoparticles via photoreduction route. The obtained samples were characterized by field emission scanning electron microscopy, X‐ray diffractometry and UV–vis diffuse reflectance spectroscopy to investigate their morphological, structural and optical properties. The SEM images show the plate morphology with the size in the range of 50–150 nm, their thickness ≈10 nm; spherical‐like Au nanoparticles ≈20 nm were attached to the surface of the WO3 plates. These materials were applied for the simultaneous photocatalytic degradation of Rhodamine B (RhB) and Cr(VI) under visible light. Due to the efficient separation of photoinduced charge carriers and the enhanced visible light absorption ability, the photocatalytic performance of Au‐decorated WO3 nanoplates was higher. The main active species responsible for the photodegradation reactions were identified by different scavengers and a photocatalytic mechanism was proposed. This work represents that WO3 nanoplates are a promising candidate for the degradation of organic and inorganic pollutants from the industrial wastewater under sun light exposure.
{"title":"Synthesis of Au‐decorated WO3 nanoplates for simultaneous oxidation of RhB and reduction of Cr(VI) under visible light irradiation","authors":"T. T. Do, Truong Giang Ho, Hong Thai Giang, Quang Ngan Pham, Duc Toan Nguyen, T. Nghiem, Trung Hieu Nguyen, Minh Tan Man","doi":"10.1002/vjch.202300268","DOIUrl":"https://doi.org/10.1002/vjch.202300268","url":null,"abstract":"Tungsten oxide (WO3) nanoplates were synthesized by a simple chemical precipitation technique. These nanoplates were decorated by Au nanoparticles via photoreduction route. The obtained samples were characterized by field emission scanning electron microscopy, X‐ray diffractometry and UV–vis diffuse reflectance spectroscopy to investigate their morphological, structural and optical properties. The SEM images show the plate morphology with the size in the range of 50–150 nm, their thickness ≈10 nm; spherical‐like Au nanoparticles ≈20 nm were attached to the surface of the WO3 plates. These materials were applied for the simultaneous photocatalytic degradation of Rhodamine B (RhB) and Cr(VI) under visible light. Due to the efficient separation of photoinduced charge carriers and the enhanced visible light absorption ability, the photocatalytic performance of Au‐decorated WO3 nanoplates was higher. The main active species responsible for the photodegradation reactions were identified by different scavengers and a photocatalytic mechanism was proposed. This work represents that WO3 nanoplates are a promising candidate for the degradation of organic and inorganic pollutants from the industrial wastewater under sun light exposure.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140242546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Phong, Dao Thi Thuong, Nguyen Ngoc Sang, Nguyen Trong Nghia, Nghiêm Thị Hà Liên, Nguyen Duc Toan, Vu Thi Thu Ha, Le Minh Thanh
Here, the role of pores in the structure of inverse opal photonic crystals (IOPC) in binding proteins in comparison with their parent photonic crystal (PC) templates has been investigated. For this purpose, polyethyleneglycol diacrylate (PEGDA) coated with SiO2‐based PC (PEGDA/SiO2‐based PC) and PEGDA‐based IOPC were attached with fluorophore Alexa 488, which is a polyclonal secondary antibody, to investigate their fluorescence emission. Scanning electron microscopy (SEM) images showed face centered cubic (fcc) packing of the PEGDA/SiO2‐based PC. And it remained after the formation of PEGDA‐based IOPC. The presence of 3‐aminopropyl triethoxysilane (APTES) and Alexa 488 that immobilized the PEGDA‐based PC and PEGDA‐based IOPC was recognized by the appearance of bands at 850, 1175, and a dominant increase in the band at 1750 cm−1. Those were attributed to (N─H) wagging, (C─N) stretching, and (C═O) stretching vibrations, respectively. Reflectance spectra showed a blue shift of the Bragg photonic band gap of the PEGDA‐based IOPC in comparison with that of the PEGDA/SiO2‐based PC. The fluorescence images showed a significant increase in the fluorescence intensity of PEGDA‐based IOPC owing to the resonance effect. These obtained results indicated the role of pores in structure of PEGDA‐based IOPC in improvement of the attachment of Alexa 488 protein.
{"title":"The role of pores in structure of polyethylenglycol diacrylate based‐inverse opal photonic crystal in binding protein applicable to optical biosensor","authors":"P. Phong, Dao Thi Thuong, Nguyen Ngoc Sang, Nguyen Trong Nghia, Nghiêm Thị Hà Liên, Nguyen Duc Toan, Vu Thi Thu Ha, Le Minh Thanh","doi":"10.1002/vjch.202300273","DOIUrl":"https://doi.org/10.1002/vjch.202300273","url":null,"abstract":"Here, the role of pores in the structure of inverse opal photonic crystals (IOPC) in binding proteins in comparison with their parent photonic crystal (PC) templates has been investigated. For this purpose, polyethyleneglycol diacrylate (PEGDA) coated with SiO2‐based PC (PEGDA/SiO2‐based PC) and PEGDA‐based IOPC were attached with fluorophore Alexa 488, which is a polyclonal secondary antibody, to investigate their fluorescence emission. Scanning electron microscopy (SEM) images showed face centered cubic (fcc) packing of the PEGDA/SiO2‐based PC. And it remained after the formation of PEGDA‐based IOPC. The presence of 3‐aminopropyl triethoxysilane (APTES) and Alexa 488 that immobilized the PEGDA‐based PC and PEGDA‐based IOPC was recognized by the appearance of bands at 850, 1175, and a dominant increase in the band at 1750 cm−1. Those were attributed to (N─H) wagging, (C─N) stretching, and (C═O) stretching vibrations, respectively. Reflectance spectra showed a blue shift of the Bragg photonic band gap of the PEGDA‐based IOPC in comparison with that of the PEGDA/SiO2‐based PC. The fluorescence images showed a significant increase in the fluorescence intensity of PEGDA‐based IOPC owing to the resonance effect. These obtained results indicated the role of pores in structure of PEGDA‐based IOPC in improvement of the attachment of Alexa 488 protein.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140242445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. B. Vo, Le Thanh Hang Nguyen, Thi Yen Tran, Thi Thuy Hang Nguyen, L. A. Nguyen, Quốc Anh Ngô
Novel green synthesis protocols of 2‐thioxo‐4‐quinazolinones starting from 2‐aminobenzamide and isothiocyanates have been reported. Method A: the reaction was carried out at 60 °C, in water, reaction time of 16 h. Method B: The reaction was carried out under solvent‐free conditions at 100 °C for 16 h. Based on these methods, six 2‐thixo‐4‐quinazolinone derivatives were synthesized with good yield. These methods have advantages, including no use of organic solvents, additives that avoid the generation of toxic waste, simple processes, cost‐effectiveness, good yields, ease of product isolation, and purification.
{"title":"Green synthesis of 2‐thioxo‐4‐quinazolinones from 2‐aminobenzamide and isothiocyanates","authors":"N. B. Vo, Le Thanh Hang Nguyen, Thi Yen Tran, Thi Thuy Hang Nguyen, L. A. Nguyen, Quốc Anh Ngô","doi":"10.1002/vjch.202300286","DOIUrl":"https://doi.org/10.1002/vjch.202300286","url":null,"abstract":"Novel green synthesis protocols of 2‐thioxo‐4‐quinazolinones starting from 2‐aminobenzamide and isothiocyanates have been reported. Method A: the reaction was carried out at 60 °C, in water, reaction time of 16 h. Method B: The reaction was carried out under solvent‐free conditions at 100 °C for 16 h. Based on these methods, six 2‐thixo‐4‐quinazolinone derivatives were synthesized with good yield. These methods have advantages, including no use of organic solvents, additives that avoid the generation of toxic waste, simple processes, cost‐effectiveness, good yields, ease of product isolation, and purification.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140243604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giang H. Le, Duong A. Thanh, Pham T. H. My, Trang T. T. Pham, Trang T. T. Quan, Quan Minh Nguyen, Quốc Anh Ngô
Fire extinguishing agents are an important factor in the fight against fires. In this study, a new composite powder (CSPMS) was synthesized and used to extinguish fires caused by petroleum products. SiO2 nanoparticles, Mg(OH)2 nanoparticles, and nanocomposites of NH4H2PO4/chitosan (CSP) were combined to generate CSPMS powder. The structure and morphology of the material were characterized using methods such as XRD, SEM, FTIR, etc. The results showed that the synthesized Mg(OH)2 nanoparticle size ranged from 20 to 30 nm, and the NH4H2PO4 nanoparticle size ranged from 800 to 900 nm on the chitosan surface. The CSPMS material had particle sizes ranging from 2 to 3 µm, with a uniform distribution of SiO2 nanoparticles (50–100 nm) and Mg(OH)2 nanoparticles on the surface. The powdered materials were applied to extinguish gasoline and oil fires. CSPMS sample demonstrated the best fire extinguishing time and powder consumption (5.8 s and 12.2 g, respectively) and CO emission below the threshold of 400 ppm. Small‐scale fire extinguishing tests showed that CSPMS powder had better fire extinguishing capability, cooling time, and CO gas adsorption ability compared to commercial fire extinguishing powder.
{"title":"Synthesis of magnesium hydroxide powder and dry powders for application in extinguishing petroleum fires","authors":"Giang H. Le, Duong A. Thanh, Pham T. H. My, Trang T. T. Pham, Trang T. T. Quan, Quan Minh Nguyen, Quốc Anh Ngô","doi":"10.1002/vjch.202300279","DOIUrl":"https://doi.org/10.1002/vjch.202300279","url":null,"abstract":"Fire extinguishing agents are an important factor in the fight against fires. In this study, a new composite powder (CSPMS) was synthesized and used to extinguish fires caused by petroleum products. SiO2 nanoparticles, Mg(OH)2 nanoparticles, and nanocomposites of NH4H2PO4/chitosan (CSP) were combined to generate CSPMS powder. The structure and morphology of the material were characterized using methods such as XRD, SEM, FTIR, etc. The results showed that the synthesized Mg(OH)2 nanoparticle size ranged from 20 to 30 nm, and the NH4H2PO4 nanoparticle size ranged from 800 to 900 nm on the chitosan surface. The CSPMS material had particle sizes ranging from 2 to 3 µm, with a uniform distribution of SiO2 nanoparticles (50–100 nm) and Mg(OH)2 nanoparticles on the surface. The powdered materials were applied to extinguish gasoline and oil fires. CSPMS sample demonstrated the best fire extinguishing time and powder consumption (5.8 s and 12.2 g, respectively) and CO emission below the threshold of 400 ppm. Small‐scale fire extinguishing tests showed that CSPMS powder had better fire extinguishing capability, cooling time, and CO gas adsorption ability compared to commercial fire extinguishing powder.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140243690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nguyen Thi Hanh, Tran Thi Thanh Thuy, Tran Huu Quang
This work reports a green method to synthesize pectin‐capped selenium nanoparticles (PT‐SeNPs) using ascorbic acid as a reductant under mild conditions. Pectin was extracted from Tithonia diversifolia (Hemsley) A. Gray plant. Pectin played the role of a capping agent preventing the agglomeration of selenium nanoparticles. The synthesized PT‐SeNPs were characterized by UV–Vis spectrophotometry, EDX spectroscopy, TEM, DLS, FT‐IR, XRD, and TG‐DTA. The TEM and DLS techniques revealed monodispersed spherical selenium nanoparticles with sizes range of 100–200 nm. The amorphous PT‐SeNPs showed a phase transformation of nanostructure at 132 °C and a sublimation at 486 °C. The anti‐inflammatory of the obtained PT‐SeNPs was investigated in ethyl phenylpropiolate (EPP)‐induced rats. Rats treated with PT‐SeNPs exhibited ear edema inhibitions of 34.8%, 43.3%, and 46.7%, respectively at 30, 60 and 90 min after EPP injection.
{"title":"Green synthesis of selenium nanoparticles capped by Tithonia diversifolia pectin for anti‐inflammation activity","authors":"Nguyen Thi Hanh, Tran Thi Thanh Thuy, Tran Huu Quang","doi":"10.1002/vjch.202300284","DOIUrl":"https://doi.org/10.1002/vjch.202300284","url":null,"abstract":"This work reports a green method to synthesize pectin‐capped selenium nanoparticles (PT‐SeNPs) using ascorbic acid as a reductant under mild conditions. Pectin was extracted from Tithonia diversifolia (Hemsley) A. Gray plant. Pectin played the role of a capping agent preventing the agglomeration of selenium nanoparticles. The synthesized PT‐SeNPs were characterized by UV–Vis spectrophotometry, EDX spectroscopy, TEM, DLS, FT‐IR, XRD, and TG‐DTA. The TEM and DLS techniques revealed monodispersed spherical selenium nanoparticles with sizes range of 100–200 nm. The amorphous PT‐SeNPs showed a phase transformation of nanostructure at 132 °C and a sublimation at 486 °C. The anti‐inflammatory of the obtained PT‐SeNPs was investigated in ethyl phenylpropiolate (EPP)‐induced rats. Rats treated with PT‐SeNPs exhibited ear edema inhibitions of 34.8%, 43.3%, and 46.7%, respectively at 30, 60 and 90 min after EPP injection.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140243568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tien Dat Doan, Yen Thi Hai Pham, Hac Thi Nhung, H. Oanh, Tuyen Nguyen Duc, Hung Quoc Le, Thu Ha Thi Vu, Phong Hong Pham, Mai Ha Hoang
This paper introduces an innovative electrochemical sensor that detects enrofloxacin (ENR) utilizing a glassy carbon electrode (GCE) modified with reduced carbon nanotubes (rCNT). The fabrication process involved a simple drop‐coating technique using water‐soluble oxidized CNTs (oCNT), followed by electrochemical reduction to obtain the rCNT/GCE electrode. The electrochemical properties of the modified electrodes, including GCE, CNT/GCE, oCNT/GCE, and rCNT/GCE, were evaluated using cyclic voltammetry and electrochemical impedance spectroscopy. The results demonstrated significantly improved electrochemical surface area and faster electron transfer rate for the rCNT/GCE electrode compared to the other configurations. Consequently, the rCNT/GCE electrode exhibited the highest electrochemical signal for ENR detection. Under optimized conditions, the rCNT/GCE‐based sensor displayed excellent performance for ENR detection. It achieved a low detection limit of 0.002 µm and demonstrated linearity within the ranges of 0.005–0.05 µm and 0.05–1.5 µm. Furthermore, the proposed sensor exhibited good selectivity, as well as excellent repeatability and reproducibility. To assess the sensor's practical utility, a quantitative analysis of ENR in shrimp meat samples was conducted. The results demonstrated the high sensitivity and accuracy of the proposed sensor in quantifying ENR, highlighting its potential as a reliable tool for environmental monitoring of water resources.
{"title":"Fabrication and application of functionalized carbon nanotubes for highly sensitive and selective sensing of enrofloxacin","authors":"Tien Dat Doan, Yen Thi Hai Pham, Hac Thi Nhung, H. Oanh, Tuyen Nguyen Duc, Hung Quoc Le, Thu Ha Thi Vu, Phong Hong Pham, Mai Ha Hoang","doi":"10.1002/vjch.202300298","DOIUrl":"https://doi.org/10.1002/vjch.202300298","url":null,"abstract":"This paper introduces an innovative electrochemical sensor that detects enrofloxacin (ENR) utilizing a glassy carbon electrode (GCE) modified with reduced carbon nanotubes (rCNT). The fabrication process involved a simple drop‐coating technique using water‐soluble oxidized CNTs (oCNT), followed by electrochemical reduction to obtain the rCNT/GCE electrode. The electrochemical properties of the modified electrodes, including GCE, CNT/GCE, oCNT/GCE, and rCNT/GCE, were evaluated using cyclic voltammetry and electrochemical impedance spectroscopy. The results demonstrated significantly improved electrochemical surface area and faster electron transfer rate for the rCNT/GCE electrode compared to the other configurations. Consequently, the rCNT/GCE electrode exhibited the highest electrochemical signal for ENR detection. Under optimized conditions, the rCNT/GCE‐based sensor displayed excellent performance for ENR detection. It achieved a low detection limit of 0.002 µm and demonstrated linearity within the ranges of 0.005–0.05 µm and 0.05–1.5 µm. Furthermore, the proposed sensor exhibited good selectivity, as well as excellent repeatability and reproducibility. To assess the sensor's practical utility, a quantitative analysis of ENR in shrimp meat samples was conducted. The results demonstrated the high sensitivity and accuracy of the proposed sensor in quantifying ENR, highlighting its potential as a reliable tool for environmental monitoring of water resources.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140243613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hoang Thi Tuyet Lan, Nguyen Thi Ngoc Mai, Bui Thi Mai Anh, Duong Thi Dung, Bui Huu Tai, Phan Van Kiem
A new megastigmane glycoside, (3S,5R,6R,9S)‐6,9‐epoxiionane‐3,5‐diol 3‐O‐β‐primeveroside (1) together with 7 compounds (2–8) were isolated from Achyranthes aspera L. The chemical structures were elucidated through 1D‐, 2D‐ NMR, and HR‐ESI‐MS experiment. The absolute configuration of 1 was determined using combination of the experimental and theoretical calculation of CD spectra. Compounds 2 and 7 were reported for the first time from the genus Achyranthes.
{"title":"Megastigmanes and other constituents from Achyranthes aspera","authors":"Hoang Thi Tuyet Lan, Nguyen Thi Ngoc Mai, Bui Thi Mai Anh, Duong Thi Dung, Bui Huu Tai, Phan Van Kiem","doi":"10.1002/vjch.202300202","DOIUrl":"https://doi.org/10.1002/vjch.202300202","url":null,"abstract":"A new megastigmane glycoside, (3S,5R,6R,9S)‐6,9‐epoxiionane‐3,5‐diol 3‐O‐β‐primeveroside (1) together with 7 compounds (2–8) were isolated from Achyranthes aspera L. The chemical structures were elucidated through 1D‐, 2D‐ NMR, and HR‐ESI‐MS experiment. The absolute configuration of 1 was determined using combination of the experimental and theoretical calculation of CD spectra. Compounds 2 and 7 were reported for the first time from the genus Achyranthes.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140247785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Le Thi Tuyet Mai, Ðo Thi Khanh Vy, Nguyen Thanh Duong
Alternating copolymers (ACs) contain two distinct monomeric unit types dispersed in alternating order of hydrophilic block and hydrophobic block. ACs have extensive and versatile applications in both academia and industry, especially in drug delivery systems (DDS) due to their unique physical and chemical properties. In the present research, poly(β‐benzyl l‐aspartate) (PBLA) was prepared by ring‐opening polymerization of BLA‐NCA. The result obtained from GPC showed that PBLA was successfully synthesized with narrow weight distribution Mw/Mn = 1.055. The outcome of copolymer has the degree of polymerization (DP) of PBLA was 50 based on the 1H NMR spectroscopy. Further, alternating copolymer poly(aspartate‐sodium) alternating poly(aspartate‐R) (PAspNa‐alt‐PAsp(Pr)), which allows the installation of expected compounds into a polymer backbone of PBLA without unwanted side effects, was synthesized via 2 steps: (1) aminolysis by 0.5 fold primary amine to attach hydrophobic group and (2) hydrolysis slowly by NaOH solution to form the hydrophilic group on the side chain of the polymer. The novel alternating copolymer synthesized successfully in this study was expected to be a promising candidate for drug delivery devices.
{"title":"Synthesis of alternating copolymer PAspNa‐alt‐PAsp(Pr) for drug delivery system","authors":"Le Thi Tuyet Mai, Ðo Thi Khanh Vy, Nguyen Thanh Duong","doi":"10.1002/vjch.202300197","DOIUrl":"https://doi.org/10.1002/vjch.202300197","url":null,"abstract":"Alternating copolymers (ACs) contain two distinct monomeric unit types dispersed in alternating order of hydrophilic block and hydrophobic block. ACs have extensive and versatile applications in both academia and industry, especially in drug delivery systems (DDS) due to their unique physical and chemical properties. In the present research, poly(β‐benzyl l‐aspartate) (PBLA) was prepared by ring‐opening polymerization of BLA‐NCA. The result obtained from GPC showed that PBLA was successfully synthesized with narrow weight distribution Mw/Mn = 1.055. The outcome of copolymer has the degree of polymerization (DP) of PBLA was 50 based on the 1H NMR spectroscopy. Further, alternating copolymer poly(aspartate‐sodium) alternating poly(aspartate‐R) (PAspNa‐alt‐PAsp(Pr)), which allows the installation of expected compounds into a polymer backbone of PBLA without unwanted side effects, was synthesized via 2 steps: (1) aminolysis by 0.5 fold primary amine to attach hydrophobic group and (2) hydrolysis slowly by NaOH solution to form the hydrophilic group on the side chain of the polymer. The novel alternating copolymer synthesized successfully in this study was expected to be a promising candidate for drug delivery devices.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140078673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A new semi‐empirical technic has been established relying on the linkage between the chemistry in the bulk liquid and that taking place in the acoustic cavitation bubble. The open‐source COPASI software has been used for the optimization of number density according to the total yield of a single bubble and the fitting of the experimental yield of hydrogen peroxide in the sonicated solution. It was observed that the number density is increased with the rise of ultrasound frequency from 200 to 1140 kHz, independently of the saturating gas nature (O2, Ar or air). Within this range of wave frequencies, i.e. from 200 to 1140 kHz, the number of active bubbles goes up from 9.35 × 107 to 3.65 × 1015 L−1 s−1. On the other side, it has been demonstrated that the number density obtained under air atmosphere is greater than that resulting either under argon or oxygen‐saturating gas. Interestingly, with respect to the saturating gas nature (O2, Ar, air) and the range of ultrasound frequency (200–1140 kHz), it was observed that the increase of number density was not necessarily accompanied by a proportional increase of void fraction (total volume of bubbles).
{"title":"A semi‐empirical approach for determining the number density and void fraction of acoustic cavitation bubbles in sono‐reactors","authors":"A. Dehane, S. Merouani","doi":"10.1002/vjch.202200207","DOIUrl":"https://doi.org/10.1002/vjch.202200207","url":null,"abstract":"A new semi‐empirical technic has been established relying on the linkage between the chemistry in the bulk liquid and that taking place in the acoustic cavitation bubble. The open‐source COPASI software has been used for the optimization of number density according to the total yield of a single bubble and the fitting of the experimental yield of hydrogen peroxide in the sonicated solution. It was observed that the number density is increased with the rise of ultrasound frequency from 200 to 1140 kHz, independently of the saturating gas nature (O2, Ar or air). Within this range of wave frequencies, i.e. from 200 to 1140 kHz, the number of active bubbles goes up from 9.35 × 107 to 3.65 × 1015 L−1 s−1. On the other side, it has been demonstrated that the number density obtained under air atmosphere is greater than that resulting either under argon or oxygen‐saturating gas. Interestingly, with respect to the saturating gas nature (O2, Ar, air) and the range of ultrasound frequency (200–1140 kHz), it was observed that the increase of number density was not necessarily accompanied by a proportional increase of void fraction (total volume of bubbles).","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140430941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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