World Journal of Plastic Surgery最新文献

The chondrocutaneous sandwich of the external ear has a delicate and complicated design, making partial ear reconstruction a challenging task for plastic surgeons. In this study, 12 patients who had surgery utilizing the conchal rotational flap and grafting approach were monitored for 1 year after surgery. The upper third of ear deformities have been repaired using a cartilaginous composite flap. Following the procedure, a year later, there were no signs of a seroma, infection, hematoma, deformity, or flap ischemia. All patients had pleasing cosmetic outcomes. The findings of this study suggest that full-thickness upper third auricular abnormalities be repaired utilizing this combination method.

Background: Free flaps are widely used for reconstructive surgery, with venous anastomosis-single or dual-being critical to flap survival. We compared outcomes between single and dual venous anastomoses.

Methods: In a cross-sectional study at Hazrat Fatemeh Hospital, Tehran, Iran, 23 patients undergoing free flap surgery were grouped by venous anastomosis type. Primary outcome was flap survival; secondary outcomes included venous thrombosis, congestion, capillary refill, and reoperation. Confounding variables (age, diabetes, smoking, ASA score) showed no significant differences.

Results: Patients with flap failure averaged 38 years; successful cases averaged 34.7 years. Flap success was higher in the dual anastomosis group (90%) than the single group (69.2%), though not statistically significant (P = 0.25). No moderate or severe congestion occurred in the dual group, which also had more cases of bright-colored flaps (58.2% vs. 41.2%, P < 0.05). Capillary refill times were similar across groups.

Conclusion: Dual venous anastomosis may reduce venous congestion and improve flap appearance, though its effect on overall flap success and thrombosis was not statistically significant. Larger studies are needed to validate these findings.

This case report describes the surgical management and outcome of a 24-year-old female engineer who suffered a total scalp avulsion injury caused by an industrial food mixer. The injury extended from the level of the eyebrows to the back of her neck and was complicated by the traumatic amputation of her right-hand first finger. Successful replantation of the scalp was achieved using microsurgical techniques, with postoperative challenges including venous congestion requiring secondary intervention. This case highlights the importance of timely surgical intervention, comprehensive trauma management, and postoperative anticoagulation in extensive avulsion injuries.

Stem cell polyphenols represent a promising avenue for enhancing wound healing through their multifaceted biological activities. Polyphenols, naturally occurring compounds with potent antioxidant properties, can modulate inflammatory responses, reduce oxidative stress, and promote the proliferation and migration of essential cells involved in tissue repair, such as fibroblasts and keratinocytes. Additionally, they play a critical role in angiogenesis, facilitating improved blood supply to healing tissues. Research indicates that the synergistic use of polyphenols with stem cell therapies could further optimize wound healing outcomes by enhancing stem cell function and survival. As conventional skin disease treatments, primarily corticosteroids, often provide only temporary relief and come with significant side effects, there is increasing interest in stem cell therapies for skin conditions. Stem cells have shown positive outcomes in treating eczema, psoriasis, diabetic wounds, and burns, utilizing both animal and plant stem cell products. However, plant-derived stem cells and natural products, including phytochemicals like resveratrol and curcumin, are preferred due to their reduced side effects and sustainability. These natural compounds aid all stages of wound healing by modulating signaling pathways associated with skin repair and regeneration, thereby minimizing residual wound effects. This review explores the effectiveness of specific natural products and introduces plant derivatives, including plant stem cells and cytokines, highlighting their potential in advancing therapeutic strategies for improved wound healing and skin regeneration. Further clinical investigations are needed to elucidate the optimal types and dosages of polyphenols for clinical applications in regenerative medicine.

Background: Peripheral nerve damage is a very important factor in patients' quality of life and functionality for various reasons. We aimed to compare the functionality level, disability and quality of life in subjects with peripheral nerve repair in the upper extremity.

Methods: This cross-sectional study was conducted on patients with nerve injuries in 2019. Among those patients, Eighty-five were selected as the sample. The instruments used in this study included the health-related quality of life standard questionnaire (SF-36), and the disability of the arm, shoulder and hand questionnaire (DASH-38). Data were analyzed by SPSS software version 22 and one-way ANOVA and Kruskal-Wallis statistical tests.

Results: Results of the Kruskal-Wallis test showed that the disability score in the groups of patients was not significant. In addition, according to the results of the one-way ANOVA test, the quality of life score was not significant among the patient groups.

Conclusion: Considering that peripheral nerve damage has a significant impact on patients' quality of life and functionality, apart from more research on the subject, it is necessary to provide support for patients to improve their quality of life.

Background: Hypertrophic scars and keloids are disorders caused by the excessive growth of connective tissue, associated with the accumulation of collagen and cellular matrix components. These scars are caused by abnormal wound healing and can have a great impact on patients' lives. Therefore, we aimed to compare the effect of intralesional injection of vitamin D with triamcinolone acetonide in the treatment of keloid.

Methods: This study was a one-sided blind clinical trial, conducted on 22 patients (44 samples) with keloid. It was a randomized, blinded clinical trial, conducted in Imam Khomeini Hospital in Ahvaz, Iran in 2022. In each group, triamcinolone or vitamin D was injected at the lesion site with an interval of three weeks and an average of 6 sessions. The patients were re-evaluated 3 months after the end of the treatment in terms of recurrence.

Results: By examining the VSS scale in each of the groups, this scale decreased significantly in both groups after the intervention (P=0.001), which was greater in the group receiving triamcinolone (P=0.001).

Conclusion: It seems that the injection of vitamin D at the site of the lesion helps to treat it, but the effectiveness of the usual triamcinolone treatment was still higher, it is suggested to use vitamin D as an adjunctive treatment in these patients.

Cases of radioactive back ulcers caused by radiation therapy have not been reported. This paper reports a matter of a 55-year-old male patient suffering from chronic back radiation ulcer after coronary stent implantation. Through the repeated and complete expansion of the rear radiation ulcer wound, the back radiation ulcer wound was successfully repaired with the reverse turnover pedicled latissimus dorsi muscle flap, and the clinical effect was satisfactory.

Many people were affected by COVID-19 in its severe form. Some intercurrences are still emerging. We here report two cases of COVID-related osteonecrosis of the jaws (CRONJ). Two retrospective cases were admitted into Imam Reza Hospital, Mashhad, Iran with suspected CRONJ. One patient escaped from hospital while the other showed a positive result after our proposed treatment. A new aftermath to COVID-19 infections is emerging. Maxillofacial and orthopedic surgeons should be aware of this situation. CRONJ should be on the suspect list in patients with COVID-19. Measures that are useful in the treatment carried out, as well as some measures recommended in the literature, were discussed. Surgical treatment of CRONJ appears to be an effective alternative, especially in the more aggressive cases.