首页 > 最新文献

World journal of radiology最新文献

英文 中文
Prediction of hepatic artery occlusion after liver transplantation by ultrasound characteristics and clinical risk factors. 通过超声波特征和临床风险因素预测肝移植后肝动脉闭塞。
IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-28 DOI: 10.4329/wjr.v16.i6.196
Yu-Ting Lai, Yi Chen, Tai-Shi Fang, Zhi-Yan Li, Ning-Bo Zhao

Background: Hepatic artery occlusion (HAO) after liver transplantation (LT) is a devastating complication, resulting in early graft loss and reduced overall survival. Ultrasound is an established assessment method for HAO in patients following LT, especially those with complex hepatic artery reconstruction.

Aim: To investigate the ultrasound characteristics and analyze the risk factors associated with HAO in patients after LT.

Methods: We retrospectively analyzed the ultrasound characteristics and the clinic risk factors associated with HAO in 400 adult LT patients who were enrolled and treated at the Third People's Hospital of Shenzhen between November 2016 and July 2022. Fourteen patients diagnosed with acute HAO (A-HAO) by surgery and fifteen diagnosed with chronic HAO (C-HAO) were included. A control group of 33 patients without HAO complications during the same period were randomly selected using a random number table. All patients underwent an ultrasonography examination. Parameters including resistance index (RI), peak systolic velocity (PSV), and portal vein velocity (PVV) were compared across the groups. Additionally, basic clinical data were collected for all patients, including gender, age, primary diagnosis, D-dimer concentration, total operation time, cold ischemia time, hot ischemia time, intraoperative blood loss and transfusion, intraoperative urine volume, infusion, model for end-stage liver disease (MELD) score, and whether complex hepatic artery reconstructions were performed. Furthermore, risk factors influencing HAO formation after LT were analyzed.

Results: Compared to the non-HAO group, PVV and RI were higher in the A-HAO group, while PSV was lower. Conversely, both PSV and RI were lower in the C-HAO group compared to the non-HAO group. The proportion of patients undergoing complex hepatic artery reconstructions and the gamma-glutamyltransferase (GGT) level before occlusion were significantly higher in the A-HAO group compared to the non-HAO group. However, there were no distinct differences between the two groups in D-dimer, MELD score, pre-occlusion alanine transaminase and aspartate transaminase levels, or intraoperative conditions.

Conclusion: Ultrasound features of the hepatic artery before occlusion are significantly associated with postoperative HAO development. Additionally, complex hepatic artery reconstructions, defined as revascularization of the graft requiring additional anastomosis between donor hepatic arteries, constitute a risk factor for A-HAO. Besides, abnormal pre-occlusion GGT elevation is an important biochemical indicator. Therefore, ultrasound examination serves as an important tool for screening HAO, especially in patients with the identified risk factors.

背景:肝移植(LT)后肝动脉闭塞(HAO)是一种破坏性并发症,会导致早期移植物损失和总体存活率降低。目的:研究肝移植术后患者的超声特征并分析与 HAO 相关的风险因素:我们回顾性分析了2016年11月至2022年7月期间在深圳市第三人民医院入院并接受治疗的400名成年LT患者的超声特征以及与HAO相关的临床风险因素。其中14名患者经手术确诊为急性HAO(A-HAO),15名患者确诊为慢性HAO(C-HAO)。使用随机数字表随机抽取 33 名同期无 HAO 并发症的患者作为对照组。所有患者均接受了超声波检查。对各组患者的阻力指数(RI)、收缩峰值速度(PSV)和门静脉速度(PVV)等参数进行比较。此外,还收集了所有患者的基本临床数据,包括性别、年龄、主要诊断、D-二聚体浓度、总手术时间、冷缺血时间、热缺血时间、术中失血量和输血量、术中尿量、输液量、终末期肝病模型(MELD)评分以及是否进行了复杂肝动脉重建。此外,还分析了影响LT术后HAO形成的风险因素:结果:与非HAO组相比,A-HAO组的PVV和RI较高,而PSV较低。相反,与非HAO组相比,C-HAO组的PSV和RI均较低。与非HAO 组相比,A-HAO 组接受复杂肝动脉重建术的患者比例和闭塞前的γ-谷氨酰转移酶(GGT)水平明显更高。然而,两组患者在D-二聚体、MELD评分、闭塞前丙氨酸转氨酶和天门冬氨酸转氨酶水平以及术中情况方面没有明显差异:结论:肝动脉闭塞前的超声特征与术后HAO的发生密切相关。此外,复杂的肝动脉重建,即需要在供体肝动脉之间进行额外吻合的移植物血管再造,也是 A-HAO 的一个危险因素。此外,闭塞前 GGT 异常升高也是一个重要的生化指标。因此,超声波检查是筛查 HAO 的重要工具,尤其是对存在上述风险因素的患者。
{"title":"Prediction of hepatic artery occlusion after liver transplantation by ultrasound characteristics and clinical risk factors.","authors":"Yu-Ting Lai, Yi Chen, Tai-Shi Fang, Zhi-Yan Li, Ning-Bo Zhao","doi":"10.4329/wjr.v16.i6.196","DOIUrl":"10.4329/wjr.v16.i6.196","url":null,"abstract":"<p><strong>Background: </strong>Hepatic artery occlusion (HAO) after liver transplantation (LT) is a devastating complication, resulting in early graft loss and reduced overall survival. Ultrasound is an established assessment method for HAO in patients following LT, especially those with complex hepatic artery reconstruction.</p><p><strong>Aim: </strong>To investigate the ultrasound characteristics and analyze the risk factors associated with HAO in patients after LT.</p><p><strong>Methods: </strong>We retrospectively analyzed the ultrasound characteristics and the clinic risk factors associated with HAO in 400 adult LT patients who were enrolled and treated at the Third People's Hospital of Shenzhen between November 2016 and July 2022. Fourteen patients diagnosed with acute HAO (A-HAO) by surgery and fifteen diagnosed with chronic HAO (C-HAO) were included. A control group of 33 patients without HAO complications during the same period were randomly selected using a random number table. All patients underwent an ultrasonography examination. Parameters including resistance index (RI), peak systolic velocity (PSV), and portal vein velocity (PVV) were compared across the groups. Additionally, basic clinical data were collected for all patients, including gender, age, primary diagnosis, D-dimer concentration, total operation time, cold ischemia time, hot ischemia time, intraoperative blood loss and transfusion, intraoperative urine volume, infusion, model for end-stage liver disease (MELD) score, and whether complex hepatic artery reconstructions were performed. Furthermore, risk factors influencing HAO formation after LT were analyzed.</p><p><strong>Results: </strong>Compared to the non-HAO group, PVV and RI were higher in the A-HAO group, while PSV was lower. Conversely, both PSV and RI were lower in the C-HAO group compared to the non-HAO group. The proportion of patients undergoing complex hepatic artery reconstructions and the gamma-glutamyltransferase (GGT) level before occlusion were significantly higher in the A-HAO group compared to the non-HAO group. However, there were no distinct differences between the two groups in D-dimer, MELD score, pre-occlusion alanine transaminase and aspartate transaminase levels, or intraoperative conditions.</p><p><strong>Conclusion: </strong>Ultrasound features of the hepatic artery before occlusion are significantly associated with postoperative HAO development. Additionally, complex hepatic artery reconstructions, defined as revascularization of the graft requiring additional anastomosis between donor hepatic arteries, constitute a risk factor for A-HAO. Besides, abnormal pre-occlusion GGT elevation is an important biochemical indicator. Therefore, ultrasound examination serves as an important tool for screening HAO, especially in patients with the identified risk factors.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interdepartmental miscommunication regarding radiology: Addressing chronic challenges and exploring solutions. 放射科部门间沟通不畅:应对长期挑战,探索解决方案。
IF 2.5 Pub Date : 2024-05-28 DOI: 10.4329/wjr.v16.i5.109
Nikolaos-Achilleas Arkoudis, Emmanouil Karofylakis, Ornella Moschovaki-Zeiger, Spyridon Prountzos, Evgenia Efthymiou, George Samonis, Christos Koutserimpas

Effective communication and collaboration among healthcare professionals are crucial for delivering high-quality patient care. Interdepartmental miscommunication poses a significant challenge to healthcare systems, potentially undermining the quality of healthcare services provided. In the same manner, communication barriers between referring physicians and radiologists can specifically affect radiology services and patient outcomes. This article attempts to put the spotlight on the ever-present chronic challenges of this issue and prompt readers to recognize the relevant potential pitfalls in their daily clinical practice. Practical solutions are explored and proposed, which should be tailored to the specific needs and issues that each individual institution may face.

医疗保健专业人员之间的有效沟通与协作对于提供高质量的病人护理至关重要。部门间的沟通不畅给医疗系统带来了巨大挑战,可能会影响医疗服务的质量。同样,转诊医生和放射科医生之间的沟通障碍也会特别影响放射科服务和患者的治疗效果。本文试图聚焦这一问题长期存在的挑战,促使读者在日常临床实践中认识到相关的潜在隐患。文章探讨并提出了切实可行的解决方案,这些方案应适合每个机构可能面临的具体需求和问题。
{"title":"Interdepartmental miscommunication regarding radiology: Addressing chronic challenges and exploring solutions.","authors":"Nikolaos-Achilleas Arkoudis, Emmanouil Karofylakis, Ornella Moschovaki-Zeiger, Spyridon Prountzos, Evgenia Efthymiou, George Samonis, Christos Koutserimpas","doi":"10.4329/wjr.v16.i5.109","DOIUrl":"10.4329/wjr.v16.i5.109","url":null,"abstract":"<p><p>Effective communication and collaboration among healthcare professionals are crucial for delivering high-quality patient care. Interdepartmental miscommunication poses a significant challenge to healthcare systems, potentially undermining the quality of healthcare services provided. In the same manner, communication barriers between referring physicians and radiologists can specifically affect radiology services and patient outcomes. This article attempts to put the spotlight on the ever-present chronic challenges of this issue and prompt readers to recognize the relevant potential pitfalls in their daily clinical practice. Practical solutions are explored and proposed, which should be tailored to the specific needs and issues that each individual institution may face.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extravasated contrast volumetric assessment on computed tomography angiography in gastrointestinal bleeding: A useful predictor of positive angiographic findings. 胃肠道出血时计算机断层扫描血管造影的外渗造影剂体积评估:血管造影阳性结果的有效预测指标。
IF 2.5 Pub Date : 2024-05-28 DOI: 10.4329/wjr.v16.i5.115
Laura Maria Cacioppa, Chiara Floridi, Alessandra Bruno, Nicolò Rossini, Tommaso Valeri, Alessandra Borgheresi, Riccardo Inchingolo, Francesco Cortese, Giacomo Novelli, Alessandro Felicioli, Mario Torresi, Pietro Boscarato, Letizia Ottaviani, Andrea Giovagnoni

Background: Gastrointestinal bleeding (GIB) is a severe and potentially life-threatening condition, especially in cases of delayed treatment. Computed tomography angiography (CTA) plays a pivotal role in the early identification of upper and lower GIB and in the prompt treatment of the haemorrhage.

Aim: To determine whether a volumetric estimation of the extravasated contrast at CTA in GIB may be a predictor of subsequent positive angiographic findings.

Methods: In this retrospective single-centre study, 35 patients (22 men; median age 69 years; range 16-92 years) admitted to our institution for active GIB detected at CTA and further submitted to catheter angiography between January 2018 and February 2022 were enrolled. Twenty-three (65.7%) patients underwent endoscopy before CTA. Bleeding volumetry was evaluated in both arterial and venous phases via a semi-automated dedicated software. Bleeding rate was obtained from volume change between the two phases and standardised for unit time. Patients were divided into two groups, according to the angiographic signs and their concordance with CTA.

Results: Upper bleeding accounted for 42.9% and lower GIB for 57.1%. Mean haemoglobin value at the admission was 7.7 g/dL. A concordance between positive CTA and direct angiographic bleeding signs was found in 19 (54.3%) cases. Despite no significant differences in terms of bleeding volume in the arterial phase (0.55 mL vs 0.33 mL, P = 0.35), a statistically significant volume increase in the venous phase was identified in the group of patients with positive angiography (2.06 mL vs 0.9 mL, P = 0.02). In the latter patient group, a significant increase in bleeding rate was also detected (2.18 mL/min vs 0.19 mL/min, P = 0.02).

Conclusion: In GIB of any origin, extravasated contrast volumetric analysis at CTA could be a predictor of positive angiography and may help in avoiding further unnecessary procedures.

背景:胃肠道出血(GIB)是一种严重且可能危及生命的疾病,尤其是在延误治疗的情况下。计算机断层扫描血管造影术(CTA)在早期识别上消化道出血和及时治疗出血方面起着关键作用。目的:确定在 CTA 中对 GIB 外渗造影剂的体积估算是否可预测随后的血管造影阳性结果:在这项回顾性单中心研究中,纳入了 2018 年 1 月至 2022 年 2 月期间因 CTA 检测出活动性 GIB 而入院并进一步接受导管血管造影的 35 名患者(22 名男性;中位年龄 69 岁;范围 16-92 岁)。23名患者(65.7%)在CTA前接受了内镜检查。通过半自动化专用软件对动脉和静脉阶段的出血量进行评估。出血率根据两个阶段之间的出血量变化得出,并以单位时间进行标准化。根据血管造影征象及其与 CTA 的一致性,将患者分为两组:结果:上部出血占 42.9%,下部 GIB 占 57.1%。入院时的平均血红蛋白值为 7.7 g/dL。19例(54.3%)CTA阳性和直接血管造影出血征象一致。尽管动脉阶段的出血量无明显差异(0.55 mL vs 0.33 mL,P = 0.35),但在血管造影阳性的患者组中,静脉阶段的出血量增加有统计学意义(2.06 mL vs 0.9 mL,P = 0.02)。在后一组患者中,出血率也明显增加(2.18 mL/min vs 0.19 mL/min,P = 0.02):结论:对于任何原因引起的 GIB,CTA 的外渗造影剂容量分析可作为血管造影阳性的预测指标,有助于避免不必要的进一步手术。
{"title":"Extravasated contrast volumetric assessment on computed tomography angiography in gastrointestinal bleeding: A useful predictor of positive angiographic findings.","authors":"Laura Maria Cacioppa, Chiara Floridi, Alessandra Bruno, Nicolò Rossini, Tommaso Valeri, Alessandra Borgheresi, Riccardo Inchingolo, Francesco Cortese, Giacomo Novelli, Alessandro Felicioli, Mario Torresi, Pietro Boscarato, Letizia Ottaviani, Andrea Giovagnoni","doi":"10.4329/wjr.v16.i5.115","DOIUrl":"10.4329/wjr.v16.i5.115","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal bleeding (GIB) is a severe and potentially life-threatening condition, especially in cases of delayed treatment. Computed tomography angiography (CTA) plays a pivotal role in the early identification of upper and lower GIB and in the prompt treatment of the haemorrhage.</p><p><strong>Aim: </strong>To determine whether a volumetric estimation of the extravasated contrast at CTA in GIB may be a predictor of subsequent positive angiographic findings.</p><p><strong>Methods: </strong>In this retrospective single-centre study, 35 patients (22 men; median age 69 years; range 16-92 years) admitted to our institution for active GIB detected at CTA and further submitted to catheter angiography between January 2018 and February 2022 were enrolled. Twenty-three (65.7%) patients underwent endoscopy before CTA. Bleeding volumetry was evaluated in both arterial and venous phases <i>via</i> a semi-automated dedicated software. Bleeding rate was obtained from volume change between the two phases and standardised for unit time. Patients were divided into two groups, according to the angiographic signs and their concordance with CTA.</p><p><strong>Results: </strong>Upper bleeding accounted for 42.9% and lower GIB for 57.1%. Mean haemoglobin value at the admission was 7.7 g/dL. A concordance between positive CTA and direct angiographic bleeding signs was found in 19 (54.3%) cases. Despite no significant differences in terms of bleeding volume in the arterial phase (0.55 mL <i>vs</i> 0.33 mL, <i>P</i> = 0.35), a statistically significant volume increase in the venous phase was identified in the group of patients with positive angiography (2.06 mL <i>vs</i> 0.9 mL, <i>P</i> = 0.02). In the latter patient group, a significant increase in bleeding rate was also detected (2.18 mL/min <i>vs</i> 0.19 mL/min, <i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>In GIB of any origin, extravasated contrast volumetric analysis at CTA could be a predictor of positive angiography and may help in avoiding further unnecessary procedures.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the potential interactions between favipiravir and radiocontrast agents. 评估法非吡拉韦与放射性对比剂之间的潜在相互作用。
IF 2.5 Pub Date : 2024-05-28 DOI: 10.4329/wjr.v16.i5.128
Sonay Aydin, Ozlem Celik Aydin, Mesut Furkan Yazar, Huseyin Aydemir, Mecit Kantarci, Sureyya Barun

Background: In cases of coronavirus disease 2019 (COVID-19), favipiravir is commonly included to the therapy regimen. Drug interactions between favipiravir and other COVID-19 therapy drugs are frequently researched. However, no research on possible drug interactions between Favipiravir and radiocontrast agents, which have become almost crucial in diagnostic processes while not being part of the treatment, has been found.

Aim: To determine potential medication interactions between Favipiravir and radiocontrast agents.

Methods: The study comprised patients who were taking Favipiravir for COVID-19 therapy and underwent a contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) test while taking the medicine. The computerized patient files of the cases included in the study, as well as the pharmacovigilance forms in the designated hospital, were evaluated for this purpose.

Results: The study included the evaluation of data from 1046 patients. The study sample's mean age was 47.23 ± 9.48 years. The mean age of cases with drug interactions was statistically significant greater than that of cases with no drug interactions (P = 0.003). When evaluated with logistic regression analysis, a 1-year raises in age increases the risk of developing drug interactions by 1.63 times (P = 0.023). There was no statistically significant difference in the occurrence of medication interactions between the sexes (P = 0.090). Possible medication interactions were discovered in 42 cases (4%).

Conclusion: The findings of this study revealed that the most notable findings as a result of the combined use of contrast agents and favipiravir were increased creatinine and transaminase values, as well as an increase in the frequency of nausea and vomiting. The majority of drug interactions discovered were modest enough that they were not reflected in the clinic. Drug interactions become more common as people get older.

背景:在冠状病毒病2019(COVID-19)的病例中,通常会将法匹拉韦纳入治疗方案。法非拉韦与其他COVID-19治疗药物之间的药物相互作用经常被研究。目的:确定法非拉韦与放射性对比剂之间潜在的药物相互作用:研究对象包括服用法维拉韦治疗 COVID-19,并在服药期间接受造影剂增强计算机断层扫描(CT)或磁共振成像(MRI)检查的患者。为此,对纳入研究的病例的计算机化患者档案以及指定医院的药物警戒表进行了评估:研究评估了 1046 名患者的数据。研究样本的平均年龄为 47.23±9.48 岁。有药物相互作用的病例的平均年龄在统计学上明显高于无药物相互作用的病例(P = 0.003)。通过逻辑回归分析评估,年龄每增加 1 岁,发生药物相互作用的风险就会增加 1.63 倍(P = 0.023)。在发生药物相互作用方面,男女之间没有明显的统计学差异(P = 0.090)。42例患者(4%)发现了可能的药物相互作用:本研究结果表明,造影剂和法非吡韦联合使用的最显著结果是肌酐和转氨酶值升高,以及恶心和呕吐的频率增加。发现的大多数药物相互作用并不严重,因此没有在临床上反映出来。随着年龄的增长,药物相互作用变得越来越常见。
{"title":"Assessment of the potential interactions between favipiravir and radiocontrast agents.","authors":"Sonay Aydin, Ozlem Celik Aydin, Mesut Furkan Yazar, Huseyin Aydemir, Mecit Kantarci, Sureyya Barun","doi":"10.4329/wjr.v16.i5.128","DOIUrl":"10.4329/wjr.v16.i5.128","url":null,"abstract":"<p><strong>Background: </strong>In cases of coronavirus disease 2019 (COVID-19), favipiravir is commonly included to the therapy regimen. Drug interactions between favipiravir and other COVID-19 therapy drugs are frequently researched. However, no research on possible drug interactions between Favipiravir and radiocontrast agents, which have become almost crucial in diagnostic processes while not being part of the treatment, has been found.</p><p><strong>Aim: </strong>To determine potential medication interactions between Favipiravir and radiocontrast agents.</p><p><strong>Methods: </strong>The study comprised patients who were taking Favipiravir for COVID-19 therapy and underwent a contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) test while taking the medicine. The computerized patient files of the cases included in the study, as well as the pharmacovigilance forms in the designated hospital, were evaluated for this purpose.</p><p><strong>Results: </strong>The study included the evaluation of data from 1046 patients. The study sample's mean age was 47.23 ± 9.48 years. The mean age of cases with drug interactions was statistically significant greater than that of cases with no drug interactions (<i>P</i> = 0.003). When evaluated with logistic regression analysis, a 1-year raises in age increases the risk of developing drug interactions by 1.63 times (<i>P</i> = 0.023). There was no statistically significant difference in the occurrence of medication interactions between the sexes (<i>P</i> = 0.090). Possible medication interactions were discovered in 42 cases (4%).</p><p><strong>Conclusion: </strong>The findings of this study revealed that the most notable findings as a result of the combined use of contrast agents and favipiravir were increased creatinine and transaminase values, as well as an increase in the frequency of nausea and vomiting. The majority of drug interactions discovered were modest enough that they were not reflected in the clinic. Drug interactions become more common as people get older.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is it a normal phenomenon for pediatric patients to have brain leptomeningeal contrast enhancement on 3-tesla magnetic resonance imaging? 儿科患者在 3 特斯拉磁共振成像中出现脑部脑膜对比度增强是正常现象吗?
IF 2.5 Pub Date : 2024-05-28 DOI: 10.4329/wjr.v16.i5.136
Min Ai, Hang-Hang Zhang, Yi Guo, Jun-Bang Feng

Determining whether sevoflurane sedation in children leads to "pseudo" prominent leptomeningeal contrast enhancement (pLMCE) on 3 Tesla magnetic resonance imaging will help reduce overdiagnosis by radiologists and clarify the pathophysiological changes of pLMCE.

确定七氟醚镇静是否会导致儿童在 3 特斯拉磁共振成像中出现 "假性 "突出脑膜对比度增强(pLMCE),将有助于减少放射科医生的过度诊断,并明确 pLMCE 的病理生理变化。
{"title":"Is it a normal phenomenon for pediatric patients to have brain leptomeningeal contrast enhancement on 3-tesla magnetic resonance imaging?","authors":"Min Ai, Hang-Hang Zhang, Yi Guo, Jun-Bang Feng","doi":"10.4329/wjr.v16.i5.136","DOIUrl":"10.4329/wjr.v16.i5.136","url":null,"abstract":"<p><p>Determining whether sevoflurane sedation in children leads to \"pseudo\" prominent leptomeningeal contrast enhancement (pLMCE) on 3 Tesla magnetic resonance imaging will help reduce overdiagnosis by radiologists and clarify the pathophysiological changes of pLMCE.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of tumors of jaw: Additive value of contrast enhancement and dual-energy computed tomography 颌骨肿瘤的特征:对比增强和双能计算机断层扫描的附加值
IF 2.5 Pub Date : 2024-04-28 DOI: 10.4329/wjr.v16.i4.82
Deepak Justine Viswanathan, A. Bhalla, S. Manchanda, Ajoy Roychoudhury, Deepika Mishra, A. Mridha
BACKGROUND Currently, the differentiation of jaw tumors is mainly based on the lesion’s morphology rather than the enhancement characteristics, which are important in the differentiation of neoplasms across the body. There is a paucity of literature on the enhancement characteristics of jaw tumors. This is mainly because, even though computed tomography (CT) is used to evaluate these lesions, they are often imaged without intravenous contrast. This study hypothesised that the enhancement characteristics of the solid component of jaw tumors can aid in the differentiation of these lesions in addition to their morphology by dual-energy CT, therefore improving the ability to differentiate between various pathologies. AIM To evaluate the role of contrast enhancement and dual-energy quantitative parameters in CT in the differentiation of jaw tumors METHODS Fifty-seven patients with jaw tumors underwent contrast-enhanced dual-energy CT. Morphological analysis of the tumor, including the enhancing solid component, was done, followed by quantitative analysis of iodine concentration (IC), water concentration (WC), HU, and normalized IC. The study population was divided into four subgroups based on histopathological analysis-central giant cell granuloma (CGCG), ameloblastoma, odontogenic keratocyst (OKC), and other jaw tumors. A one-way ANOVA test for parametric variables and the Kruskal-Wallis test for non-parametric variables were used. If significant differences were found, a series of independent t -tests or Mann-Whitney U tests were used. RESULTS Ameloblastoma was the most common pathology (n = 20), followed by CGCG (n = 11) and OKC. CGCG showed a higher mean concentration of all quantitative parameters than ameloblastomas (P < 0.05). An IC threshold of 31.35 × 100 μg/cm3 had the maximum sensitivity (81.8%) and specificity (65%). Between ameloblastomas and OKC, the former showed a higher mean concentration of all quantitative parameters (P < 0.001), however when comparing unilocular ameloblastomas with OKCs, the latter showed significantly higher WC. Also, ameloblastoma had a higher IC and lower WC compared to “other jaw tumors” group. CONCLUSION Enhancement characteristics of solid components combined with dual-energy parameters offer a more precise way to differentiate between jaw tumors.
背景 目前,颌骨肿瘤的分化主要基于病变的形态而非增强特征,而增强特征对全身肿瘤的分化非常重要。有关颌骨肿瘤增强特征的文献很少。这主要是因为,尽管计算机断层扫描(CT)被用来评估这些病变,但它们通常是在没有静脉注射对比剂的情况下成像的。本研究假设,颌骨肿瘤实体成分的增强特征除了有助于通过双能 CT 对病变的形态进行分辨外,还有助于提高对不同病理的分辨能力。目的 评估对比增强和双能 CT 定量参数在颌骨肿瘤分化中的作用 方法 57 名颌骨肿瘤患者接受了对比增强双能 CT 检查。首先对肿瘤(包括增强的实体部分)进行形态学分析,然后对碘浓度(IC)、水浓度(WC)、HU 和归一化 IC 进行定量分析。根据组织病理学分析,研究对象被分为四个亚组--中央巨细胞肉芽肿(CGCG)、釉母细胞瘤、牙源性角化囊肿(OKC)和其他颌骨肿瘤。参数变量采用单向方差分析,非参数变量采用 Kruskal-Wallis 检验。如果发现有明显差异,则进行一系列独立 t 检验或 Mann-Whitney U 检验。结果 骨髓母细胞瘤是最常见的病理类型(20 例),其次是 CGCG(11 例)和 OKC。CGCG 的所有定量参数的平均浓度均高于釉母细胞瘤(P < 0.05)。IC 阈值为 31.35 × 100 μg/cm3 的灵敏度(81.8%)和特异度(65%)最高。在牙釉质母细胞瘤和 OKC 之间,前者的所有定量参数的平均浓度都更高(P < 0.001),但在比较单眼牙釉质母细胞瘤和 OKC 时,后者的 WC 明显更高。此外,与 "其他颌骨肿瘤 "组相比,釉母细胞瘤的 IC 值更高,而 WC 值更低。结论 固体成分的增强特征与双能量参数相结合,为区分颌骨肿瘤提供了一种更精确的方法。
{"title":"Characterization of tumors of jaw: Additive value of contrast enhancement and dual-energy computed tomography","authors":"Deepak Justine Viswanathan, A. Bhalla, S. Manchanda, Ajoy Roychoudhury, Deepika Mishra, A. Mridha","doi":"10.4329/wjr.v16.i4.82","DOIUrl":"https://doi.org/10.4329/wjr.v16.i4.82","url":null,"abstract":"BACKGROUND\u0000 Currently, the differentiation of jaw tumors is mainly based on the lesion’s morphology rather than the enhancement characteristics, which are important in the differentiation of neoplasms across the body. There is a paucity of literature on the enhancement characteristics of jaw tumors. This is mainly because, even though computed tomography (CT) is used to evaluate these lesions, they are often imaged without intravenous contrast. This study hypothesised that the enhancement characteristics of the solid component of jaw tumors can aid in the differentiation of these lesions in addition to their morphology by dual-energy CT, therefore improving the ability to differentiate between various pathologies.\u0000 AIM\u0000 To evaluate the role of contrast enhancement and dual-energy quantitative parameters in CT in the differentiation of jaw tumors\u0000 METHODS\u0000 Fifty-seven patients with jaw tumors underwent contrast-enhanced dual-energy CT. Morphological analysis of the tumor, including the enhancing solid component, was done, followed by quantitative analysis of iodine concentration (IC), water concentration (WC), HU, and normalized IC. The study population was divided into four subgroups based on histopathological analysis-central giant cell granuloma (CGCG), ameloblastoma, odontogenic keratocyst (OKC), and other jaw tumors. A one-way ANOVA test for parametric variables and the Kruskal-Wallis test for non-parametric variables were used. If significant differences were found, a series of independent t -tests or Mann-Whitney U tests were used.\u0000 RESULTS\u0000 Ameloblastoma was the most common pathology (n = 20), followed by CGCG (n = 11) and OKC. CGCG showed a higher mean concentration of all quantitative parameters than ameloblastomas (P < 0.05). An IC threshold of 31.35 × 100 μg/cm3 had the maximum sensitivity (81.8%) and specificity (65%). Between ameloblastomas and OKC, the former showed a higher mean concentration of all quantitative parameters (P < 0.001), however when comparing unilocular ameloblastomas with OKCs, the latter showed significantly higher WC. Also, ameloblastoma had a higher IC and lower WC compared to “other jaw tumors” group.\u0000 CONCLUSION\u0000 Enhancement characteristics of solid components combined with dual-energy parameters offer a more precise way to differentiate between jaw tumors.","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140652030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic ultrasound-guided tissue acquisition for the diagnosis of focal liver lesion 内窥镜超声引导下组织采集用于诊断肝脏病灶
IF 2.5 Pub Date : 2024-04-28 DOI: 10.4329/wjr.v16.i4.72
A. Tanțău, Cosmina Sutac, Anamaria Pop, M. Tantău
In patients with liver tumors, the histopathology examination can assist in diagnosis, staging, prognosis, and therapeutic management strategy. Endoscopic ultrasound (EUS)-guided tissue acquisition using fine needle aspiration (FNA) or more newly fine needle biopsy (FNB) is a well-developed technique in order to evaluate and differentiate the liver masses. The goal of the EUS-FNA or EUS-FNB is to provide an accurate sample for a histopathology examination. Therefore, malignant tumors such as hepatocarcinoma, cholangiocarcinoma and liver metastasis or benign tumors such as liver adenoma, focal hyperplastic nodular tumors and cystic lesions can be accurately diagnosed using EUS-guided tissue acquisition. EUS-FNB using 19 or 22 Ga needle provide longer samples and a higher diagnostic accuracy in patients with liver masses when compared with EUS-FNA. Few data are available on the diagnostic accuracy of EUS-FNB when compared with percutaneously, ultrasound, computer tomography or transjugulary-guided liver biopsies. This review will discuss the EUS-guided tissue acquisition options in patients with liver tumors and its efficacy and safety in providing accurate samples. The results of the last studies comparing EUS-guided liver biopsy with other conventional techniques are presented. The EUS-guided tissue acquisition using FNB can be a suitable technique in suspected liver lesions in order to provide an accurate histopathology diagnosis, especially for those who require endoscopy.
组织病理学检查有助于肝脏肿瘤患者的诊断、分期、预后和治疗策略。内窥镜超声(EUS)引导下的细针穿刺术(FNA)或最新的细针活检术(FNB)是一种成熟的组织采集技术,用于评估和区分肝脏肿块。EUS-FNA 或 EUS-FNB 的目的是为组织病理学检查提供准确的样本。因此,肝癌、胆管癌和肝转移瘤等恶性肿瘤或肝腺瘤、局灶性增生结节瘤和囊性病变等良性肿瘤都能通过 EUS 引导下的组织采集得到准确诊断。与 EUS-FNA 相比,使用 19 或 22 Ga 穿刺针的 EUS-FNB 取样时间更长,对肝脏肿块患者的诊断准确率更高。关于 EUS-FNB 与经皮、超声、计算机断层扫描或经颈静脉引导的肝活检相比的诊断准确性,目前鲜有数据。本综述将讨论在 EUS 引导下对肝肿瘤患者进行组织采集的选择及其提供准确样本的有效性和安全性。本文还将介绍最近几项比较 EUS 引导下肝脏活检与其他传统技术的研究结果。在 EUS 引导下使用 FNB 采集组织是一种适用于疑似肝脏病变的技术,可提供准确的组织病理学诊断,尤其适用于需要进行内镜检查的患者。
{"title":"Endoscopic ultrasound-guided tissue acquisition for the diagnosis of focal liver lesion","authors":"A. Tanțău, Cosmina Sutac, Anamaria Pop, M. Tantău","doi":"10.4329/wjr.v16.i4.72","DOIUrl":"https://doi.org/10.4329/wjr.v16.i4.72","url":null,"abstract":"In patients with liver tumors, the histopathology examination can assist in diagnosis, staging, prognosis, and therapeutic management strategy. Endoscopic ultrasound (EUS)-guided tissue acquisition using fine needle aspiration (FNA) or more newly fine needle biopsy (FNB) is a well-developed technique in order to evaluate and differentiate the liver masses. The goal of the EUS-FNA or EUS-FNB is to provide an accurate sample for a histopathology examination. Therefore, malignant tumors such as hepatocarcinoma, cholangiocarcinoma and liver metastasis or benign tumors such as liver adenoma, focal hyperplastic nodular tumors and cystic lesions can be accurately diagnosed using EUS-guided tissue acquisition. EUS-FNB using 19 or 22 Ga needle provide longer samples and a higher diagnostic accuracy in patients with liver masses when compared with EUS-FNA. Few data are available on the diagnostic accuracy of EUS-FNB when compared with percutaneously, ultrasound, computer tomography or transjugulary-guided liver biopsies. This review will discuss the EUS-guided tissue acquisition options in patients with liver tumors and its efficacy and safety in providing accurate samples. The results of the last studies comparing EUS-guided liver biopsy with other conventional techniques are presented. The EUS-guided tissue acquisition using FNB can be a suitable technique in suspected liver lesions in order to provide an accurate histopathology diagnosis, especially for those who require endoscopy.","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140652028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pseudoaneurysm formation following transarterial embolization of traumatic carotid-cavernous fistula with detachable balloon: An institutional cohort long-term study 使用可拆卸球囊经动脉栓塞治疗外伤性颈动脉-海绵窦瘘后假动脉瘤的形成:一项机构队列长期研究
IF 2.5 Pub Date : 2024-04-28 DOI: 10.4329/wjr.v16.i4.94
Prasert Iampreechakul, Korrapakc Wangtanaphat, Songpol Chuntaroj, Yodkhwan Wattanasen, Sunisa Hangsapruek, Punjama Lertbutsayanukul, Pimchanok Puthkhao, S. Siriwimonmas
BACKGROUND The goal of therapy for traumatic carotid-cavernous fistula (TCCF) is the elimination of fistula while maintaining patency of the parent artery. The treatment for TCCF has evolved from surgery to endovascular management using detachable balloons, coils, liquid embolic agents, covered stents, or flow-diverter stent through arterial or venous approaches. Despite the withdrawal of detachable balloons from the market in the United States since 2004, transarterial embolization with detachable balloons has currently remained the best initial treatment for TCCF in several countries. However, the pseudoaneurysm formation following transarterial detachable balloon embolization has rarely been observed in long-term follow-up. AIM To determine the occurrence and long-term follow-up of pseudoaneurysm after transarterial detachable balloon for TCCF. METHODS Between January 2009 and December 2019, 79 patients diagnosed with TCCF were treated using detachable latex balloons (GOLDBAL) of four sizes. Pseudoaneurysm sizes were stratified into five grades for analysis. Initial and follow-up assessments involved computed tomography angiography at 1 month, 6 month, 1 year, and longer intervals for significant cases. Clinical follow-ups occurred semi-annually for 2 years, then annually. Factors analyzed included sex, age, fistula size and location, and balloon size. RESULTS In our cohort of 79 patients treated for TCCF, pseudoaneurysms formed in 67.1%, with classifications ranging from grade 0 to grade 3; no grade 4 or giant pseudoaneurysms were observed. The majority of pseudoaneurysms did not progress in size, and some regressed spontaneously. Calcifications developed in most large pseudoaneurysms over 5-10 years. Parent artery occlusion occurred in 7.6% and recurrent fistulas in 16.5%. The primary risk factors for pseudoaneurysm formation were identified as the use of specific balloon sizes, with balloon SP and No. 6 significantly associated with its occurrence (P = 0.005 and P = 0.002, respectively), whereas sex, age, fistula size, location, and the number of balloons used were not significant predictors. CONCLUSION Pseudoaneurysm formation following detachable balloon embolization for TCCF is common, primarily influenced by the size of the balloon used. Despite this, all patients with pseudoaneurysms remained asymptomatic during long-term follow-up.
背景创伤性颈动脉海绵瘘(TCCF)的治疗目标是在保持母动脉通畅的同时消除瘘管。TCCF 的治疗方法已从手术发展到通过动脉或静脉途径使用可拆卸球囊、线圈、液体栓塞剂、有盖支架或分流支架进行血管内治疗。尽管可分离球囊自 2004 年起在美国退出市场,但在一些国家,使用可分离球囊进行经动脉栓塞目前仍是治疗 TCCF 的最佳初始疗法。然而,经动脉可分离球囊栓塞术后假性动脉瘤的形成在长期随访中很少被观察到。目的 探讨经动脉可取球囊治疗 TCCF 后假性动脉瘤的发生率和长期随访情况。方法 2009年1月至2019年12月期间,使用四种规格的可分离乳胶球囊(GOLDBAL)治疗了79例确诊为TCCF的患者。假性动脉瘤大小分为五个等级进行分析。初次和随访评估包括 1 个月、6 个月、1 年的计算机断层扫描血管造影,重大病例的评估间隔时间更长。临床随访每半年进行一次,为期两年,之后每年进行一次。分析因素包括性别、年龄、瘘管大小和位置以及球囊大小。结果 在我们治疗的 79 例 TCCF 患者中,67.1% 形成了假性动脉瘤,分级从 0 级到 3 级不等;未观察到 4 级或巨大假性动脉瘤。大多数假性动脉瘤的大小没有增大,有些会自动消退。大多数大的假性动脉瘤在 5-10 年后出现钙化。7.6%的假动脉瘤发生了母动脉闭塞,16.5%的假动脉瘤发生了复发性瘘。假性动脉瘤形成的主要风险因素是使用特定尺寸的球囊,其中 SP 号和 6 号球囊与假性动脉瘤的形成有显著相关性(分别为 P = 0.005 和 P = 0.002),而性别、年龄、瘘管大小、位置和使用球囊的数量则无显著预测作用。结论 可分离球囊栓塞治疗 TCCF 后形成假性动脉瘤很常见,主要受所用球囊大小的影响。尽管如此,所有假性动脉瘤患者在长期随访期间仍无症状。
{"title":"Pseudoaneurysm formation following transarterial embolization of traumatic carotid-cavernous fistula with detachable balloon: An institutional cohort long-term study","authors":"Prasert Iampreechakul, Korrapakc Wangtanaphat, Songpol Chuntaroj, Yodkhwan Wattanasen, Sunisa Hangsapruek, Punjama Lertbutsayanukul, Pimchanok Puthkhao, S. Siriwimonmas","doi":"10.4329/wjr.v16.i4.94","DOIUrl":"https://doi.org/10.4329/wjr.v16.i4.94","url":null,"abstract":"BACKGROUND\u0000 The goal of therapy for traumatic carotid-cavernous fistula (TCCF) is the elimination of fistula while maintaining patency of the parent artery. The treatment for TCCF has evolved from surgery to endovascular management using detachable balloons, coils, liquid embolic agents, covered stents, or flow-diverter stent through arterial or venous approaches. Despite the withdrawal of detachable balloons from the market in the United States since 2004, transarterial embolization with detachable balloons has currently remained the best initial treatment for TCCF in several countries. However, the pseudoaneurysm formation following transarterial detachable balloon embolization has rarely been observed in long-term follow-up.\u0000 AIM\u0000 To determine the occurrence and long-term follow-up of pseudoaneurysm after transarterial detachable balloon for TCCF.\u0000 METHODS\u0000 Between January 2009 and December 2019, 79 patients diagnosed with TCCF were treated using detachable latex balloons (GOLDBAL) of four sizes. Pseudoaneurysm sizes were stratified into five grades for analysis. Initial and follow-up assessments involved computed tomography angiography at 1 month, 6 month, 1 year, and longer intervals for significant cases. Clinical follow-ups occurred semi-annually for 2 years, then annually. Factors analyzed included sex, age, fistula size and location, and balloon size.\u0000 RESULTS\u0000 In our cohort of 79 patients treated for TCCF, pseudoaneurysms formed in 67.1%, with classifications ranging from grade 0 to grade 3; no grade 4 or giant pseudoaneurysms were observed. The majority of pseudoaneurysms did not progress in size, and some regressed spontaneously. Calcifications developed in most large pseudoaneurysms over 5-10 years. Parent artery occlusion occurred in 7.6% and recurrent fistulas in 16.5%. The primary risk factors for pseudoaneurysm formation were identified as the use of specific balloon sizes, with balloon SP and No. 6 significantly associated with its occurrence (P = 0.005 and P = 0.002, respectively), whereas sex, age, fistula size, location, and the number of balloons used were not significant predictors.\u0000 CONCLUSION\u0000 Pseudoaneurysm formation following detachable balloon embolization for TCCF is common, primarily influenced by the size of the balloon used. Despite this, all patients with pseudoaneurysms remained asymptomatic during long-term follow-up.","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140652027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence for disease diagnostics still has a long way to go 用于疾病诊断的人工智能还有很长的路要走
IF 2.5 Pub Date : 2024-03-28 DOI: 10.4329/wjr.v16.i3.69
Jian-She Yang, Qiang Wang, Zhong-Wei Lv
Artificial intelligence (AI) can sometimes resolve difficulties that other advanced technologies and humans cannot. In medical diagnostics, AI has the advantage of processing figure recognition, especially for images with similar characteristics that are difficult to distinguish with the naked eye. However, the mechanisms of this advanced technique should be well-addressed to elucidate clinical issues. In this letter, regarding an original study presented by Takayama et al , we suggest that the authors should effectively illustrate the mechanism and detailed procedure that artificial intelligence techniques processing the acquired images, including the recognition of non-obvious difference between the normal parts and pathological ones, which were impossible to be distinguished by naked eyes, such as the basic constitutional elements of pixels and grayscale, special molecules or even some metal ions which involved into the diseases occurrence.
人工智能(AI)有时可以解决其他先进技术和人类无法解决的难题。在医疗诊断中,人工智能在处理图形识别方面具有优势,特别是对于肉眼难以分辨的具有相似特征的图像。然而,这种先进技术的机制应该得到很好的解决,以阐明临床问题。在这封信中,针对高山等人提出的一项原创性研究,我们建议作者应有效说明人工智能技术处理所获图像的机制和详细过程,包括识别正常部分和病理部分之间的非明显差异,这些差异是肉眼无法区分的,例如像素和灰度的基本组成元素、特殊分子,甚至一些与疾病发生有关的金属离子。
{"title":"Artificial intelligence for disease diagnostics still has a long way to go","authors":"Jian-She Yang, Qiang Wang, Zhong-Wei Lv","doi":"10.4329/wjr.v16.i3.69","DOIUrl":"https://doi.org/10.4329/wjr.v16.i3.69","url":null,"abstract":"Artificial intelligence (AI) can sometimes resolve difficulties that other advanced technologies and humans cannot. In medical diagnostics, AI has the advantage of processing figure recognition, especially for images with similar characteristics that are difficult to distinguish with the naked eye. However, the mechanisms of this advanced technique should be well-addressed to elucidate clinical issues. In this letter, regarding an original study presented by Takayama et al , we suggest that the authors should effectively illustrate the mechanism and detailed procedure that artificial intelligence techniques processing the acquired images, including the recognition of non-obvious difference between the normal parts and pathological ones, which were impossible to be distinguished by naked eyes, such as the basic constitutional elements of pixels and grayscale, special molecules or even some metal ions which involved into the diseases occurrence.","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140370124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating pediatric ureteropelvic junction obstruction: Dynamic magnetic resonance urography vs renal scintigraphy 99m-technetium mercaptoacetyltriglycine 评估小儿输尿管盆腔交界处梗阻:动态磁共振尿路造影与肾脏闪烁造影 99m-锝巯基乙酰三甘氨酸比较
IF 2.5 Pub Date : 2024-03-28 DOI: 10.4329/wjr.v16.i3.49
Yousuf Al-Shaqsi, M. Peycelon, A. Paye-Jaouen, E. Carricaburu, Anca Tanase, C. Grapin-Dagorno, Alaa El-Ghoneimi
BACKGROUND Ureteropelvic junction obstruction (UPJO) is a common congenital urinary tract disorder in children. It can be diagnosed as early as in utero due to the presence of hydronephrosis or later in life due to symptomatic occurrence. AIM To evaluate the discrepancy between dynamic contrast-enhanced magnetic resonance urography (dMRU) and scintigraphy 99m-technetium mercaptoacetyltriglycine (MAG-3) for the functional evaluation of UPJO. METHODS Between 2016 and 2020, 126 patients with UPJO underwent surgery at Robert Debré Hospital. Of these, 83 received a prenatal diagnosis, and 43 were diagnosed during childhood. Four of the 126 patients underwent surgery based on the clinical situation and postnatal ultrasound findings without undergoing functional imaging evaluation. Split renal function was evaluated preoperatively using scintigraphy MAG-3 (n = 28), dMRU (n = 53), or both (n = 40). In this study, we included patients who underwent surgery for UPJO and scintigraphy MAG-3 + dMRU but excluded those who underwent only scintigraphy MAG-3 or dMRU. The patients were divided into groups A (< 10% discrepancy) and B (> 10% discrepancy). We examined the discrepancy in split renal function between the two modalities and investigated the possible risk factors. RESULTS The split renal function between the two kidneys was compared in 40 patients (28 boys and 12 girls) using scintigraphy MAG-3 and dMRU. Differential renal function, as determined using both modalities, showed a difference of < 10% in 31 children and > 10% in 9 children. Calculation of the relative renal function using dMRU revealed an excellent correlation coefficient with renal scintigraphy MAG-3 for both kidneys. CONCLUSION Our findings demonstrated that dMRU is equivalent to scintigraphy MAG-3 for evaluating split renal function in patients with UPJO.
背景输尿管盆腔连接处梗阻(UPJO)是儿童常见的先天性泌尿系统疾病。这种疾病最早可在子宫内因肾积水而被诊断出来,也可在出生后因出现症状而被诊断出来。目的 评估动态对比增强磁共振尿路造影(dMRU)与闪烁成像 99m-锝巯基乙酰三甘氨酸(MAG-3)对 UPJO 功能评估的差异。方法 2016年至2020年间,126名UPJO患者在罗伯特-德布雷医院接受了手术。其中,83人在产前确诊,43人在儿童时期确诊。在这126名患者中,有4名患者根据临床情况和产后超声检查结果接受了手术,而没有进行功能成像评估。术前使用闪烁成像 MAG-3(28 例)、dMRU(53 例)或两者(40 例)对分裂肾功能进行评估。在本研究中,我们纳入了接受 UPJO 手术和 MAG-3 + dMRU 闪烁扫描的患者,但排除了仅接受 MAG-3 或 dMRU 闪烁扫描的患者。患者被分为 A 组(差异<10%)和 B 组(差异>10%)。我们研究了两种模式下肾功能分化的差异,并调查了可能的风险因素。结果 使用闪烁成像 MAG-3 和 dMRU 对 40 名患者(28 名男孩和 12 名女孩)的双肾功能进行了比较。使用这两种方法测定的肾功能差异显示,31 名儿童的差异小于 10%,9 名儿童的差异大于 10%。使用 dMRU 计算的相对肾功能与肾脏闪烁成像 MAG-3 的相关系数极高。结论 我们的研究结果表明,在评估 UPJO 患者的分肾功能时,dMRU 与闪烁成像 MAG-3 具有同等作用。
{"title":"Evaluating pediatric ureteropelvic junction obstruction: Dynamic magnetic resonance urography vs renal scintigraphy 99m-technetium mercaptoacetyltriglycine","authors":"Yousuf Al-Shaqsi, M. Peycelon, A. Paye-Jaouen, E. Carricaburu, Anca Tanase, C. Grapin-Dagorno, Alaa El-Ghoneimi","doi":"10.4329/wjr.v16.i3.49","DOIUrl":"https://doi.org/10.4329/wjr.v16.i3.49","url":null,"abstract":"BACKGROUND\u0000 Ureteropelvic junction obstruction (UPJO) is a common congenital urinary tract disorder in children. It can be diagnosed as early as in utero due to the presence of hydronephrosis or later in life due to symptomatic occurrence.\u0000 AIM\u0000 To evaluate the discrepancy between dynamic contrast-enhanced magnetic resonance urography (dMRU) and scintigraphy 99m-technetium mercaptoacetyltriglycine (MAG-3) for the functional evaluation of UPJO.\u0000 METHODS\u0000 Between 2016 and 2020, 126 patients with UPJO underwent surgery at Robert Debré Hospital. Of these, 83 received a prenatal diagnosis, and 43 were diagnosed during childhood. Four of the 126 patients underwent surgery based on the clinical situation and postnatal ultrasound findings without undergoing functional imaging evaluation. Split renal function was evaluated preoperatively using scintigraphy MAG-3 (n = 28), dMRU (n = 53), or both (n = 40). In this study, we included patients who underwent surgery for UPJO and scintigraphy MAG-3 + dMRU but excluded those who underwent only scintigraphy MAG-3 or dMRU. The patients were divided into groups A (< 10% discrepancy) and B (> 10% discrepancy). We examined the discrepancy in split renal function between the two modalities and investigated the possible risk factors.\u0000 RESULTS\u0000 The split renal function between the two kidneys was compared in 40 patients (28 boys and 12 girls) using scintigraphy MAG-3 and dMRU. Differential renal function, as determined using both modalities, showed a difference of < 10% in 31 children and > 10% in 9 children. Calculation of the relative renal function using dMRU revealed an excellent correlation coefficient with renal scintigraphy MAG-3 for both kidneys.\u0000 CONCLUSION\u0000 Our findings demonstrated that dMRU is equivalent to scintigraphy MAG-3 for evaluating split renal function in patients with UPJO.","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140373419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
World journal of radiology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1