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[Delphi Expert Consensus of the German Society for Thoracic Surgery on Segmentectomy for Non-small Cell Lung Cancer]. [德国胸外科学会关于非小细胞肺癌分段切除术的德尔菲专家共识]。
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-07-04 DOI: 10.1055/a-2099-5793
Aris Koryllos, Stefanie Veit, Olaf Schega, Gunda Leschber, Corinna Ludwig

Background: Findings from two recently published randomised controlled trials have shown favourable oncological results of segmentectomy for early-stage NSCLC < 2 cm. This has generated a growing interest in this procedure, which is however considered technically more challenging than lobectomy. The aim of the working group of the German Society for Thoracic Surgery (DGT) was to address, via an expert consensus project, topics concerning implementation of segmentectomy in lung cancer surgery.

Methods: The assigned group of the DGT designed and conducted two electronic rounds of questions in all major thoracic and lung cancer centres in Germany. The steering group predefined a priori the threshold of consensus of 75% or greater. The results were discussed in an expert meeting, leading to a final Delphi poll for selected topics and questions.

Results: Thirty-eight questions on segmentectomy for NSCLC were proposed in two rounds and voted on. After the final Delphi process, a consensus was reached for the following topics: non-inferiority of segmentectomy vs. lobectomy for tumours < 2 cm, segmentectomy as an alternative if lobectomy is functionally not feasible, use of intraoperative techniques for identification of intersegmental borders. No consensus could be reached for topics such as frozen section for intraoperative ascertainment of radicality, as also for the indication of a re-do lobectomy in case of an occult N1 lymph node status.

Conclusion: Our manuscript depicts the results of a Delphi process in 2020/2021 involving experts of the German Society for Thoracic Surgery on the implementation of segmentectomy in lung cancer patients. In general, a very high rate of consensus was documented for the majority of the topics concerning the indication and execution of lung segmentectomy.

背景:最近发表的两项随机对照试验结果表明,对早期 NSCLC 进行分段切除术具有良好的肿瘤效果:DGT 的指定小组设计并在德国所有主要胸腔和肺癌中心进行了两轮电子提问。指导小组事先设定了 75% 或更高的共识阈值。专家会议对结果进行了讨论,最终对选定的主题和问题进行了德尔菲投票:经过两轮投票,共提出了 38 个有关 NSCLC 分部切除术的问题。经过最后的德尔菲程序,就以下主题达成了共识:肿瘤分段切除术与肿瘤叶切除术的非劣效性 结论:我们的手稿描述了 2020/2021 年德尔菲程序的结果,德国胸外科学会的专家参与了该程序,讨论了肺癌患者分段切除术的实施问题。总体而言,关于肺段切除术的适应症和实施的大部分主题都达成了非常高的共识。
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引用次数: 0
[Thoracic Surgery during Pregnancy and Breastfeeding - an Interdisciplinary Consensus Paper]. [妊娠期和哺乳期胸外科手术--跨学科共识文件]。
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-05-15 DOI: 10.1055/a-2074-7405
Isabella Metelmann, Uta-Carolin Pietsch, Silke Kappelmeyer, Sven Wessela, Maya Niethard, Laura Klotz

If thoracic surgery is to remain an attractive career path for young physicians, it is essential to provide opportunities to balance work, residency, and family time. With an increasing proportion of women in thoracic surgery, it has become increasingly important to create a work environment that allows safe employment during pregnancy and breast feeding becomes an important concern.Based on the legal requirements of the German Maternity Protection Act (Mutterschutzgesetz), this interdisciplinary consensus paper was developed by representatives of thoracic surgery, anaesthesiology, and occupational medicine.The vast majority of thoracic operations can be performed by pregnant or breast-feeding surgeons. We established a risk-stratified list of operations with potentially acceptable risk, and a list of operations that pregnant or breast-feeding surgeons should not perform. A checklist aims to aid the individual implementation of thoracic surgery during pregnancy and breast feeding.Thoracic surgery can be performed by pregnant or breast-feeding surgeons when certain protective measures are observed. The prerequisite is the voluntary and independent decision of the surgeon, and the implementation of safety precautions by the employer.

胸外科要想继续成为对年轻医生有吸引力的职业道路,就必须提供平衡工作、实习和家庭时间的机会。随着胸外科女医生的比例越来越高,创造一个允许怀孕和哺乳期间安全工作的工作环境变得越来越重要。根据德国《孕产妇保护法》(Mutterschutzgesetz)的法律要求,胸外科、麻醉科和职业医学科的代表共同制定了这份跨学科共识文件。我们制定了一份风险分级清单,列出了具有潜在可接受风险的手术,以及怀孕或哺乳期外科医生不应实施的手术。在遵守某些保护措施的情况下,怀孕或哺乳期的外科医生可以进行胸外科手术。前提条件是外科医生自愿和独立做出决定,以及雇主采取安全预防措施。
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引用次数: 0
[Modern Perioperative Care Concepts in Thoracic Surgery: Enhanced Recovery After Thoracic Surgery (ERATS)]. [现代胸外科围手术期护理概念:胸外科手术后的强化恢复 (ERATS)]。
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2022-06-22 DOI: 10.1055/a-1823-1207
Tomas Piler, Marcus Creutzenberg, Hans-Stefan Hofmann, Michael Ried

In modern perioperative care concepts, multimodal ERAS (Enhanced Recovery After Surgery) is a multimodal perioperative treatment concept for improving postoperative recovery of surgical patients after an operation. This is managed by the so-called ERAS Society and through which hospitals can also be officially certified. The focus of the ERAS concept is on uniform patient care from admission to discharge, with the aim of improving perioperative processes by implementing evidence-based protocols involving a multidisciplinary treatment team. In 2019, ERAS guidelines were published for the first time by the European Society of Thoracic Surgery (ESTS), in cooperation with the ERAS Society, for specific lung resection procedures, and these identified a total of 45 graduated recommendations or Enhanced Recovery Pathways (ERP). The implementation of ERAS concepts in thoracic surgery (ERATS = Enhanced Recovery After Thoracic Surgery) is intended to establish standardised perioperative procedures based on study results and/or expert recommendations. These recommendations take into account organisational aspects as well as thoracic surgical and anaesthesiological procedures, with the overriding goal of creating a structured treatment plan tailored to the patient. All these measures should result in a multimodal overall concept, which should primarily lead to an improved outcome after elective thoracic surgery and secondarily to shorter hospital stays with correspondingly lower costs.This review article describes basic ERAS principles and provides a compact presentation of the most important European ERAS recommendations from the authors' point of view, together with typical obstacles to the implementation of the corresponding ERATS program in German thoracic surgery.

在现代围手术期护理理念中,多模式 ERAS(术后强化恢复)是一种多模式围手术期治疗理念,用于改善手术患者的术后恢复。它由所谓的 ERAS 协会管理,医院也可通过该协会获得正式认证。ERAS概念的重点是对患者从入院到出院进行统一护理,目的是通过实施以循证医学为基础、涉及多学科治疗团队的方案来改善围手术期流程。2019年,欧洲胸外科学会(ESTS)与ERAS学会合作,首次发布了针对特定肺切除术的ERAS指南,共确定了45项分级建议或增强康复路径(ERP)。在胸外科手术中实施ERAS概念(ERATS=胸外科术后强化恢复)旨在根据研究结果和/或专家建议建立标准化的围手术期程序。这些建议考虑到了组织方面以及胸外科手术和麻醉程序,其首要目标是为患者量身定制结构化的治疗方案。本综述文章介绍了ERAS的基本原则,并从作者的角度简要介绍了最重要的欧洲ERAS建议,以及在德国胸外科实施相应ERATS计划的典型障碍。
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引用次数: 0
[Watch and Wait for Rectal Cancer]. [直肠癌的观察与等待]。
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2024-03-05 DOI: 10.1055/a-2241-0334
Carolin Kastner, Michael Meir, Sven Flemming, Joachim Reibetanz, Christoph Thomas Germer, Armin Wiegering

About one third of all colorectal carcinomas (CRC) are localised in the rectum. As part of a multimodal therapy concept, neoadjuvant therapy achieves downstaging of the tumour in 50-60% of cases and a so-called complete clinical response (cCR), defined as clinically (and radiologically) undetectable residual tumour after completion of neoadjuvant therapy, in 10-30% of cases.In view of the perioperative morbidity and mortality associated with radical rectal resection, including the occurrence of a symptom complex known as low anterior resection syndrome (LARS) and the need for deviation, at least temporarily, the question of the risk-benefit balance of organ resection in the presence of cCR has been raised. In this context, the therapeutic concept of a "watch-and-wait" approach with omission of immediate organ resection and inclusion in a structured surveillance regime, has emerged.For a safe, oncological implementation of this option, it is necessary to develop standards in the definition of a suitable patient clientele and the implementation of the concept. In addition to the initial correct selection of the patient group that is suitable for a primarily non-surgical procedure, the inherent goal is the early and sufficient detection of tumour recurrence (so-called local regrowth) during the "watch-and-wait" phase (surveillance).In this context, in this paper we address the questions of: 1. the optimal timing of initial re-staging, 2. the criteria for assessing the clinical response and selecting the appropriate patient clientele, 3. the rhythm and design of the surveillance protocol.

约有三分之一的结直肠癌(CRC)发生在直肠。作为多模式治疗概念的一部分,新辅助治疗在 50-60% 的病例中实现了肿瘤的分期,在 10-30% 的病例中实现了所谓的完全临床反应 (cCR),即在完成新辅助治疗后临床(和放射)上检测不到残留肿瘤。考虑到根治性直肠切除术的围手术期发病率和死亡率,包括低位前切除综合征(LARS)症状的出现,以及至少暂时偏离的需要,人们提出了在出现 cCR 的情况下进行器官切除的风险-效益平衡问题。在这种情况下,出现了 "观察和等待 "的治疗理念,即不立即进行器官切除,而是纳入结构化的监测体系。为了安全地从肿瘤学角度实施这一方案,有必要在定义合适的患者对象和实施这一理念方面制定标准。除了最初正确选择适合主要采用非手术治疗的患者群体外,其固有的目标是在 "观察和等待 "阶段(监测)及早充分地发现肿瘤复发(即所谓的局部再生):1. 首次再分期的最佳时机;2. 评估临床反应和选择合适患者的标准;3. 监测方案的节奏和设计。
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引用次数: 0
[Chylothorax]. [乳糜胸]。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2024-02-01 Epub Date: 2024-03-05 DOI: 10.1055/a-1990-4896
David B Ellebrecht, Michael Hoge, Sönke von Weihe

Chylothorax is a serious and potentially life-threatening condition of diverse etiology. This article provides a detailed overview of anatomy, physiology, etiology, diagnosis, and therapeutic options in the context of chylothorax.

乳糜胸是一种严重且可能危及生命的疾病,其病因多种多样。本文详细概述了乳糜胸的解剖学、生理学、病因学、诊断和治疗方案。
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引用次数: 0
Das neue Ehegattennotvertretungsrecht. 新的配偶代表法。
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2024-03-05 DOI: 10.1055/a-2178-7084
Jörg Staatsmann
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引用次数: 0
Editorial. 社论
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2024-03-05 DOI: 10.1055/a-2171-7766
Michael Ghadimi
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引用次数: 0
Hygienestandards im OP – führen sie nachhaltig zur Verbesserung der Qualität? 手术室的卫生标准--是否能持续提高质量?
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2024-03-05 DOI: 10.1055/a-2219-4023
Mathias Holz, Sebastian Lippross, Andreas Seekamp

Background: In Germany, nosocomial infections and postoperative wound infections are a significant burden for the healthcare system and the patients affected. A postoperative wound infection is often accompanied by a massive deterioration in the quality of the treatment success of surgical measures in terms of patient stress, the functional results and the cost-effectiveness of a treatment for the service provider. The aim of this article is to present the current hygiene requirements for the perioperative setting in a comprehensible manner and to explain them to everyone involved in the surgical procedure.

Method: First of all, the importance of hygienic measures is explained, as well as a brief overview of the development up to modern hygiene concepts of today. Then the current recommendations of the KRINKO (Commission for Hospital Hygiene and Infection Prevention at the Robert Koch Institute): "Prevention of postoperative wound infections, recommendation of the Commission for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute" are presented.

Conclusion: Hygienic work is a basic prerequisite for work in the surgical area, because convincing treatment results with good functional results cannot be achieved in many areas (e.g. modern endoprosthetics) without sufficient hygiene. The modern requirements for hygienic work are complex and affect all areas of the hospital. The best possible degree of process quality can only be guaranteed if all pillars of modern hygiene concepts are observed.

背景:在德国,院内感染和术后伤口感染对医疗系统和受影响的患者来说都是一个沉重的负担。术后伤口感染通常会导致手术治疗的质量大幅下降,从而影响患者的心理压力、功能效果以及服务提供商的治疗成本效益。本文旨在以通俗易懂的方式介绍目前围手术期的卫生要求,并向参与手术过程的每个人解释这些要求:方法:首先,解释卫生措施的重要性,并简要概述发展到今天的现代卫生概念。然后是 KRINKO(罗伯特-科赫研究所医院卫生和感染预防委员会)的现行建议:介绍了 "预防术后伤口感染,罗伯特-科赫研究所医院卫生和感染预防委员会(KRINKO)的建议":卫生工作是外科领域工作的基本前提,因为如果没有足够的卫生条件,在许多领域(如现代假体内固定术)就无法实现令人信服的治疗效果和良好的功能效果。现代卫生工作的要求非常复杂,影响到医院的所有领域。只有遵守现代卫生理念的所有支柱,才能保证最佳的流程质量。
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引用次数: 0
[Endoscopic Resection Techniques for Precancerous and Early Cancerous Lesions in the Rectum]. [直肠癌前病变和早期癌变的内窥镜切除技术]。
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2024-03-05 DOI: 10.1055/a-2256-6724
Jürgen Hochberger, Martin Loss, Elena Kruse

Today, endoscopy plays a decisive role not only in the detection of colorectal adenomas and carcinomas, but also in the treatment of precancerous lesions, in particular flat adenomas and early carcinomas. In recent years, endoscopic submucosal dissection (ESD) has become increasingly important alongside classic polypectomy and mucosal resection after saline injection using a snare (EMR). Using ESD the lesion is marked, injected submucosally using viscous substances and the mucosa incised and tunneled with a transparent cap and a fine diathermy knife. Particularly in the case of widespread and high-risk lesions ESD enables a quasi-surgical "en bloc" resection almost regardless of size, with a histological R0 resection rate of far over 90% in specialized centers. ESD enables an excellent histopathological evaluation and has a low recurrence risk of 1-3%. Endoscopic full-thickness resection using a dedicated device (FTRD system) represents another addition to the armamentarium. It can be used for circumscribed submucosal, suspicious or scarred changes up to 2 cm in the middle and upper rectum. Endoscopic intermuscular dissection (EID) enables histopathological analysis of the complete submucosa beyond the mucosa and upper submucosal layer by including the circular inner muscle layer within the resection specimen. It reduces basal R1 situations and offers a new perspective for T1 carcinomas through curative, organ-preserving endoscopic therapy, especially in the case of deep submucosal infiltration alone, without other risk factors for metastases. Indications, the procedure itself and significance of the various techniques for premalignant and early malignant lesions in the rectum are presented.

如今,内窥镜不仅在检测结直肠腺瘤和癌方面发挥着决定性作用,而且在治疗癌前病变,尤其是扁平腺瘤和早期癌方面也发挥着重要作用。近年来,内镜黏膜下剥离术(ESD)与传统的息肉切除术和使用套管(EMR)注射生理盐水后的黏膜切除术一样,变得越来越重要。使用 ESD 对病灶进行标记,使用粘性物质在粘膜下注射,然后使用透明帽和精细电热刀对粘膜进行切口和隧道切割。特别是在病变范围广、风险高的情况下,ESD 几乎可以实现 "整体 "切除的准外科手术,无论病变大小,在专业中心的组织学 R0 切除率远远超过 90%。ESD 可进行出色的组织病理学评估,复发风险低至 1-3%。使用专用设备(FTRD 系统)进行内窥镜全厚切除术是另一种新的治疗手段。它可用于直肠中上部 2 厘米以内的环形粘膜下、可疑或瘢痕性病变。内镜下肌层间剥离术(EID)通过将环形内肌层包括在切除标本中,可以对粘膜和粘膜上层以外的完整粘膜下层进行组织病理学分析。它减少了基底 R1 的情况,并通过治愈性、保留器官的内窥镜疗法为 T1 癌症提供了一个新的视角,尤其是在仅有粘膜下层深部浸润、无其他转移风险因素的情况下。本文介绍了直肠癌前病变和早期恶性病变的适应症、手术本身以及各种技术的意义。
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引用次数: 0
[Staging and Diagnostics of Rectal Cancer]. [直肠癌的分期和诊断]。
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2024-03-05 DOI: 10.1055/a-2252-2320
Omar Al-Bourini, Lorenz Biggemann, Ali Seif

The review titled "Staging and Diagnostics of Rectal Cancer" aims to provide insight to imaging techniques in patients with rectal cancer.Rectal cancer is among the most common malignancies, with one of the highest mortality rates worldwide. Timely diagnosis and therapy of this cancer therefore has important socio-economic implications.Radiological imaging plays a major role in the planning of subsequent therapy. Modern tomographic imaging is used not only for initial diagnosis, but also for staging.The individual role of different imaging techniques in diagnosis of rectal cancer will be explained in detail, and their function in general. Furthermore, we will present relevant radiological research related.The increasing role of MRI-based local staging will be presented in detail in this review. Defined diagnostic criteria, based on common recommendations, will be explained. We will show how MRI-based local staging can support the initial diagnosis and follow-up examinations in collaboration with other medical specialties in therapeutic planning. In particular, we describe how MRI is capable of substantially influencing the determination of surgical procedures in rectal cancer.

这篇题为 "直肠癌的分期和诊断 "的综述旨在为直肠癌患者提供影像技术方面的见解。直肠癌是最常见的恶性肿瘤之一,也是全球死亡率最高的恶性肿瘤之一。因此,及时诊断和治疗这种癌症具有重要的社会经济意义。现代断层成像技术不仅可用于初步诊断,还可用于分期。我们将详细介绍不同成像技术在直肠癌诊断中的各自作用,以及它们的一般功能。此外,我们还将介绍相关的放射学研究。本综述将详细介绍基于核磁共振成像的局部分期所发挥的日益重要的作用。本综述将详细介绍基于核磁共振成像的局部分期所发挥的日益重要的作用,并将解释基于常见建议的定义诊断标准。我们将展示基于核磁共振成像的局部分期如何支持初步诊断和后续检查,并与其他医疗专科合作制定治疗计划。特别是,我们将介绍磁共振成像如何对直肠癌手术的决定产生重大影响。
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引用次数: 0
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Zentralblatt fur Chirurgie
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