首页 > 最新文献

Zentralblatt fur Chirurgie最新文献

英文 中文
[Effects of the Minimum Volume Requirement in Surgical Lung Cancer Therapy - an Analysis from the Patient's Perspective]. [肺癌手术治疗中最小容积需求的影响——从患者角度分析]。
IF 0.7 4区 医学 Q4 SURGERY Pub Date : 2025-07-31 DOI: 10.1055/a-2652-4779
Dominik Lobinger, Andreas Hiebinger, Christian Geltner, Florian Eicher, Gudrun Groß, Iyad Shalabi, Alicia Reiche, Ekaterina Mamonova, Johannes Bodner

Due to a legislative decision, a minimum volume for the surgical treatment of lung cancer has been applied since the beginning of 2024 in Germany. This has led to a change in care structure, with the result that some patients are now being treated further away from home in an unfamiliar environment.Patient survey using standardised questionnaires, descriptive analysis of results.No more anatomical lung resections were performed at the Donau Isar Klinikum in 2024, as a consequence of the minimum volume requirement. Since then, these procedures have been performed at the Clinic for Thoracic Surgery at the Munich Bogenhausen Clinic, a certified lung cancer centre. 68% of patients (n = 25) felt sufficiently informed in advance about why their operation could not be performed near their home. 80% of respondents had not heard about the new regulation beforehand. The fact that they would be operated on in a certified centre, but would have to travel a longer distance, provided reassurance among those affected (60%; 84% among relatives), but also uncertainty (24%), incomprehension (20%) and anger (12%). The average distance to the lung cancer centre was 143.4 km (∅ 1 h 48 min). All patients were satisfied with the contact and appointment process (1: very dissatisfied/10: very satisfied, ∅ 9.3), the information about the procedure (∅ 9.4), the overall stay (∅ 9.2), the medical and nursing treatment (∅ 9.7/9.3) and the rooms and catering (∅ 8.6). The majority (76%) did not experience the longer return journey as stressful. The communication and cooperation between the primary treating physicians and the lung cancer centre was rated as good; almost all would recommend the lung cancer centre.The feedback from the patients affected by the changed guidelines was positive. The perceived safety and quality of treatment at a centre of excellence compensated for the existing uncertainty about the unfamiliar environment and the disappointment about the associated inconvenience. Although the insights gained must be confirmed by an ongoing survey and the experiences of other centres, the concept of centring complex interventions in the field of surgical lung cancer therapy appears to be supported by those affected.

由于一项立法决定,自2024年初以来,德国已经应用了肺癌手术治疗的最低剂量。这导致了护理结构的变化,结果是一些病人现在在离家较远的陌生环境中接受治疗。患者调查采用标准化问卷,对结果进行描述性分析。Donau Isar Klinikum在2024年没有再进行解剖性肺切除术,因为需要最小的体积。从那时起,这些手术在慕尼黑Bogenhausen诊所的胸外科诊所进行,这是一家经过认证的肺癌中心。68%的患者(n = 25)提前充分了解为什么他们的手术不能在他们家附近进行。80%的受访者事先没有听说过新规定。事实上,他们将在一个认证的中心进行手术,但需要长途跋涉,这让那些受影响的人(60%;(亲属中占84%),但也有不确定(24%)、不理解(20%)和愤怒(12%)。到肺癌中心的平均距离为143.4 km(∅1 h 48 min)。患者对就诊预约流程满意(1:非常不满意/10:非常满意,∅9.3),对手术信息满意(∅9.4),对总体住院费满意(∅9.2),对医疗护理满意(∅9.7/9.3),对房食满意(∅8.6)。大多数人(76%)认为返程时间较长并不会带来压力。基层主治医师与肺癌中心的沟通合作被评为良好;几乎所有人都会推荐肺癌中心。受改变指南影响的患者的反馈是积极的。卓越中心治疗的安全性和质量弥补了对不熟悉环境的不确定性和对相关不便的失望。虽然所获得的见解必须通过正在进行的调查和其他中心的经验来证实,但在肺癌手术治疗领域集中复杂干预的概念似乎得到了那些受影响的人的支持。
{"title":"[Effects of the Minimum Volume Requirement in Surgical Lung Cancer Therapy - an Analysis from the Patient's Perspective].","authors":"Dominik Lobinger, Andreas Hiebinger, Christian Geltner, Florian Eicher, Gudrun Groß, Iyad Shalabi, Alicia Reiche, Ekaterina Mamonova, Johannes Bodner","doi":"10.1055/a-2652-4779","DOIUrl":"https://doi.org/10.1055/a-2652-4779","url":null,"abstract":"<p><p>Due to a legislative decision, a minimum volume for the surgical treatment of lung cancer has been applied since the beginning of 2024 in Germany. This has led to a change in care structure, with the result that some patients are now being treated further away from home in an unfamiliar environment.Patient survey using standardised questionnaires, descriptive analysis of results.No more anatomical lung resections were performed at the Donau Isar Klinikum in 2024, as a consequence of the minimum volume requirement. Since then, these procedures have been performed at the Clinic for Thoracic Surgery at the Munich Bogenhausen Clinic, a certified lung cancer centre. 68% of patients (n = 25) felt sufficiently informed in advance about why their operation could not be performed near their home. 80% of respondents had not heard about the new regulation beforehand. The fact that they would be operated on in a certified centre, but would have to travel a longer distance, provided reassurance among those affected (60%; 84% among relatives), but also uncertainty (24%), incomprehension (20%) and anger (12%). The average distance to the lung cancer centre was 143.4 km (∅ 1 h 48 min). All patients were satisfied with the contact and appointment process (1: very dissatisfied/10: very satisfied, ∅ 9.3), the information about the procedure (∅ 9.4), the overall stay (∅ 9.2), the medical and nursing treatment (∅ 9.7/9.3) and the rooms and catering (∅ 8.6). The majority (76%) did not experience the longer return journey as stressful. The communication and cooperation between the primary treating physicians and the lung cancer centre was rated as good; almost all would recommend the lung cancer centre.The feedback from the patients affected by the changed guidelines was positive. The perceived safety and quality of treatment at a centre of excellence compensated for the existing uncertainty about the unfamiliar environment and the disappointment about the associated inconvenience. Although the insights gained must be confirmed by an ongoing survey and the experiences of other centres, the concept of centring complex interventions in the field of surgical lung cancer therapy appears to be supported by those affected.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Student Training in Surgical Wound Care: Development and Curricular Implementation of a Course for the Improvement of Practical Skills and Expertise]. [外科伤口护理的学生训练:提高实践技能和专业知识课程的开发和课程实施]。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-06-03 DOI: 10.1055/a-2615-5997
Pernilla Virginia Conrad, Gudrun Karsten, Regine Gläser, Charlotte Hauser, Katrin Hertrampf

Wound care is an important medical skill that is not an important part of medical training. National and international studies show that the teaching of wounds is inadequate in medical curricula and that there is a desire for further training among students. Therefore the aim of this project was to improve students' expertise in surgical wound care.Following a survey of students in their 2nd clinical and practical year (n = 169) at the Faculty of Medicine in Kiel that addressed their level of knowledge of wound care, an innovative teaching concept was designed, including a practical section using real-life models. The pilot course was held in the summer semester of 2023 and the learning success was determined by a pre-post survey of the entire semester. The course was then implemented into the curriculum.The assessment of the level of knowledge revealed important uncertainties. In the practical year, 39.7% were confident in aseptic wound care. Training in wound care was rated as inadequate. Completion of our course resulted in an increase in the assessment of their own skills. The identified uncertainties were reduced by the training: 75% of students were confident in wound care.This course improves medical education, can be easily implemented in any faculty and could lead to improved patient care.

伤口护理是一项重要的医学技能,不是医学培训的重要组成部分。国内和国际研究表明,医学课程中关于伤口的教学不足,学生们希望得到进一步的培训。因此,本项目的目的是提高学生在外科伤口护理方面的专业知识。在对基尔医学院第二临床和实践学年的学生(n = 169)进行调查后,我们设计了一种创新的教学理念,包括使用现实生活模型的实践部分。试点课程于2023年夏季学期开始,通过对整个学期的前后调查来确定学习成功与否。这门课程随后被落实到课程中。对知识水平的评估揭示了重要的不确定性。在实践年度,39.7%的人对无菌伤口护理有信心。伤口护理方面的培训被认为是不够的。完成我们的课程导致了对自己技能评估的提高。培训减少了确定的不确定性:75%的学生对伤口护理有信心。本课程改善了医学教育,可以很容易地在任何院系实施,并可以改善病人的护理。
{"title":"[Student Training in Surgical Wound Care: Development and Curricular Implementation of a Course for the Improvement of Practical Skills and Expertise].","authors":"Pernilla Virginia Conrad, Gudrun Karsten, Regine Gläser, Charlotte Hauser, Katrin Hertrampf","doi":"10.1055/a-2615-5997","DOIUrl":"https://doi.org/10.1055/a-2615-5997","url":null,"abstract":"<p><p>Wound care is an important medical skill that is not an important part of medical training. National and international studies show that the teaching of wounds is inadequate in medical curricula and that there is a desire for further training among students. Therefore the aim of this project was to improve students' expertise in surgical wound care.Following a survey of students in their 2nd clinical and practical year (n = 169) at the Faculty of Medicine in Kiel that addressed their level of knowledge of wound care, an innovative teaching concept was designed, including a practical section using real-life models. The pilot course was held in the summer semester of 2023 and the learning success was determined by a pre-post survey of the entire semester. The course was then implemented into the curriculum.The assessment of the level of knowledge revealed important uncertainties. In the practical year, 39.7% were confident in aseptic wound care. Training in wound care was rated as inadequate. Completion of our course resulted in an increase in the assessment of their own skills. The identified uncertainties were reduced by the training: 75% of students were confident in wound care.This course improves medical education, can be easily implemented in any faculty and could lead to improved patient care.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
34. Jahrestagung der Deutschen Gesellschaft für Thoraxchirurgie (D-A-CH-Tagung): Einladung nach Bregenz. 34. 德国胸外科学会年会(D-A-CH-Tagung):邀请至布列根茨。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-06-01 Epub Date: 2025-06-03 DOI: 10.1055/a-2580-1327
Robert Scheubel
{"title":"34. Jahrestagung der Deutschen Gesellschaft für Thoraxchirurgie (D-A-CH-Tagung): Einladung nach Bregenz.","authors":"Robert Scheubel","doi":"10.1055/a-2580-1327","DOIUrl":"https://doi.org/10.1055/a-2580-1327","url":null,"abstract":"","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":"150 3","pages":"251-253"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perspektiven der Transplantationschirurgie – zwischen technologischem Fortschritt und strukturellen Herausforderungen. 移植手术的前景:技术进步与结构挑战之间。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-06-01 Epub Date: 2025-06-03 DOI: 10.1055/a-2502-3538
Jörg C Kalff, Tim Oliver Vilz
{"title":"Perspektiven der Transplantationschirurgie – zwischen technologischem Fortschritt und strukturellen Herausforderungen.","authors":"Jörg C Kalff, Tim Oliver Vilz","doi":"10.1055/a-2502-3538","DOIUrl":"https://doi.org/10.1055/a-2502-3538","url":null,"abstract":"","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":"150 3","pages":"207-208"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Centralisation of Liver Transplantation: Implications for Training Transplant Surgeons]. [肝移植的集中化:对移植外科医生培训的启示]。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-06-01 Epub Date: 2025-05-05 DOI: 10.1055/a-2587-2394
Simon Moosburner, Nathanael Raschzok, Wenzel Schoening, Brigitta Globke, Johann Pratschke, Robert Öllinger, Felix Krenzien

The centralisation of liver transplantation in Germany is seen as a promising approach to improve care quality through higher case volumes and specialised structures. However, it poses significant challenges for surgical training. Reduced availability of training positions, limited diversity of clinical experience, and the risk of capacity bottlenecks could impact the education of young transplant surgeons in the long term. This article explores the opportunities and risks of centralisation, particularly regarding surgical education. While higher case volumes are associated with better outcomes, it is argued that complementary measures such as regional support structures, rotation programs, and, where applicable, the use of practical training models are essential to ensure comprehensive education. The implementation of regulations of minimum case volume is also discussed as a potential regulatory tool. Finally, the article highlights the need for future studies to systematically evaluate the impact of centralisation on surgical education and to provide an evidence-based foundation for decision making.

在德国,肝移植的集中化被认为是一种有希望的方法,可以通过更高的病例量和专门的结构来提高护理质量。然而,这对外科培训提出了重大挑战。培训岗位的减少、临床经验的有限多样性以及能力瓶颈的风险可能会影响年轻移植外科医生的长期教育。本文探讨了集中化的机会和风险,特别是在外科教育方面。虽然较高的病例量与较好的结果相关,但有人认为,区域支持结构、轮转方案以及在适用的情况下使用实用培训模式等补充措施对于确保全面教育至关重要。本文还讨论了实施最小案件量法规作为一种潜在的监管工具。最后,文章强调了未来的研究需要系统地评估集中化对外科教育的影响,并为决策提供循证基础。
{"title":"[Centralisation of Liver Transplantation: Implications for Training Transplant Surgeons].","authors":"Simon Moosburner, Nathanael Raschzok, Wenzel Schoening, Brigitta Globke, Johann Pratschke, Robert Öllinger, Felix Krenzien","doi":"10.1055/a-2587-2394","DOIUrl":"10.1055/a-2587-2394","url":null,"abstract":"<p><p>The centralisation of liver transplantation in Germany is seen as a promising approach to improve care quality through higher case volumes and specialised structures. However, it poses significant challenges for surgical training. Reduced availability of training positions, limited diversity of clinical experience, and the risk of capacity bottlenecks could impact the education of young transplant surgeons in the long term. This article explores the opportunities and risks of centralisation, particularly regarding surgical education. While higher case volumes are associated with better outcomes, it is argued that complementary measures such as regional support structures, rotation programs, and, where applicable, the use of practical training models are essential to ensure comprehensive education. The implementation of regulations of minimum case volume is also discussed as a potential regulatory tool. Finally, the article highlights the need for future studies to systematically evaluate the impact of centralisation on surgical education and to provide an evidence-based foundation for decision making.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":" ","pages":"223-229"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bedeutung von KI und Robotik für die Viszeralchirurgie. 人工智能和机器人在内脏手术中的重要性。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-06-01 Epub Date: 2025-06-03 DOI: 10.1055/a-2498-0445
Tobias Keck
{"title":"Bedeutung von KI und Robotik für die Viszeralchirurgie.","authors":"Tobias Keck","doi":"10.1055/a-2498-0445","DOIUrl":"https://doi.org/10.1055/a-2498-0445","url":null,"abstract":"","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":"150 3","pages":"191-193"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Status of Robotics in Living Donor Liver and Kidney Transplantation - Review of the Literature and Results of a Survey among German Transplant Centres]. [机器人技术在活体供体肝脏和肾脏移植中的地位-文献综述和德国移植中心调查结果]。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-06-01 Epub Date: 2025-03-20 DOI: 10.1055/a-2538-8802
Cornelius J van Beekum, Ulrich Zwirner, Dennis Kleine-Döpke, Gerrit Grannas, Jessica Singh, Nicolas Richter, Moritz Schmelzle, Philipp Felgendreff, Markus Quante

The advantages of minimally invasive surgical techniques are undisputed. With the introduction of robotic assistance systems, classic laparoscopy has been further developed and is now also being utilized in transplant surgery, which was previously mainly characterised by open surgical procedures, particularly in living donor liver and kidney donations. In order to assess the current implementation status of robotic assistance systems in transplant surgery, international studies in this field were summarized and correlated with a national survey on the use of robotic assistance systems in living donation.First, a narrative summary of the MEDLINE-listed publications on robotic living kidney and liver donation was carried out. In addition, an online survey was conducted among German transplant centres with ten questions on the utilization of robotic techniques in Germany.Retrospective cohort studies at a small number of transplant centres worldwide report particular advantages of robotics, especially regarding blood loss, patient comfort and length of hospital stay. One-third of German transplant centres already perform living kidney donations with robotic assistance, and one-fifth of centres even use this technique in over 90% of cases. In contrast, living liver donations are only performed in one German transplant centre using robotic assistance for left lateral liver resection of the donor.In the context of living donation, advocates of robotics emphasise technical advantages, greater patient comfort and a steeper learning curve. A persistent and significant point of criticism regarding robotic surgical techniques remains the prolonged warm ischemia time, especially during learning curves. The survey results presented here demonstrate that there is still a substantial need for discussion on this current topic. However, there is a lack of prospective randomised controlled studies.

微创手术技术的优势是无可争议的。随着机器人辅助系统的引入,传统的腹腔镜手术得到了进一步的发展,现在也被用于移植手术,这在以前主要以开放手术为特征,特别是在活体肝脏和肾脏捐赠中。为了评估机器人辅助系统在移植手术中的实施现状,总结了该领域的国际研究,并与一项关于机器人辅助系统在活体捐赠中的使用的国家调查相关联。首先,对medline列出的关于机器人活体肾脏和肝脏捐赠的出版物进行了叙述性总结。此外,在德国的移植中心进行了一项在线调查,提出了十个关于德国使用机器人技术的问题。在全球少数移植中心进行的回顾性队列研究报告了机器人技术的特殊优势,特别是在失血、患者舒适度和住院时间方面。三分之一的德国移植中心已经在机器人协助下进行活体肾脏捐赠,五分之一的中心甚至在90%以上的病例中使用了这项技术。相比之下,活体肝脏捐献仅在德国的一个移植中心进行,使用机器人辅助供体左侧肝脏切除。在活体捐赠的背景下,机器人技术的支持者强调技术优势,更大的患者舒适度和更陡峭的学习曲线。关于机器人手术技术的一个持续和重要的批评点仍然是延长的热缺血时间,特别是在学习曲线期间。这里提出的调查结果表明,仍有很大的需要讨论这个当前的话题。然而,缺乏前瞻性随机对照研究。
{"title":"[Status of Robotics in Living Donor Liver and Kidney Transplantation - Review of the Literature and Results of a Survey among German Transplant Centres].","authors":"Cornelius J van Beekum, Ulrich Zwirner, Dennis Kleine-Döpke, Gerrit Grannas, Jessica Singh, Nicolas Richter, Moritz Schmelzle, Philipp Felgendreff, Markus Quante","doi":"10.1055/a-2538-8802","DOIUrl":"10.1055/a-2538-8802","url":null,"abstract":"<p><p>The advantages of minimally invasive surgical techniques are undisputed. With the introduction of robotic assistance systems, classic laparoscopy has been further developed and is now also being utilized in transplant surgery, which was previously mainly characterised by open surgical procedures, particularly in living donor liver and kidney donations. In order to assess the current implementation status of robotic assistance systems in transplant surgery, international studies in this field were summarized and correlated with a national survey on the use of robotic assistance systems in living donation.First, a narrative summary of the MEDLINE-listed publications on robotic living kidney and liver donation was carried out. In addition, an online survey was conducted among German transplant centres with ten questions on the utilization of robotic techniques in Germany.Retrospective cohort studies at a small number of transplant centres worldwide report particular advantages of robotics, especially regarding blood loss, patient comfort and length of hospital stay. One-third of German transplant centres already perform living kidney donations with robotic assistance, and one-fifth of centres even use this technique in over 90% of cases. In contrast, living liver donations are only performed in one German transplant centre using robotic assistance for left lateral liver resection of the donor.In the context of living donation, advocates of robotics emphasise technical advantages, greater patient comfort and a steeper learning curve. A persistent and significant point of criticism regarding robotic surgical techniques remains the prolonged warm ischemia time, especially during learning curves. The survey results presented here demonstrate that there is still a substantial need for discussion on this current topic. However, there is a lack of prospective randomised controlled studies.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":" ","pages":"230-242"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Indications for Lung Transplantation - Updates Since the Last ISHLT Recommendations]. [肺移植适应症-自上次ISHLT建议以来的更新]。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-06-01 Epub Date: 2025-05-15 DOI: 10.1055/a-2563-3691
Zsofia Kovacs, Alberto Benazzo, Peter Jaksch

Lung transplantation has evolved continuously since its first successful procedures in the 1960 s. The current guidelines from the International Society for Heart and Lung Transplantation (ISHLT) emphasise increasingly individualised patient assessment, which, in addition to the underlying lung disease, considers factors such as comorbidities, frailty, age, and social aspects. The expanded indications for lung transplantation are reflected in the refined risk assessment, which particularly includes patients with advanced chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), and pulmonary arterial hypertension (PAH). Furthermore, the criteria for patients with a history of cancer and those with infections such as HIV or multidrug-resistant organisms have been made more flexible, leading to a more inclusive transplantation policy. A key focus is on early transplant counselling, allowing patients the opportunity for transplantation before they develop acute exacerbations. These updated guidelines aim to maximise both the survival rates and the quality of life of transplant patients, through differentiated and risk-adjusted decision-making.

自20世纪60年代首次成功手术以来,肺移植不断发展。国际心肺移植学会(ISHLT)目前的指南强调越来越个性化的患者评估,除了潜在的肺部疾病外,还考虑合并症、虚弱、年龄和社会方面等因素。肺移植适应症的扩大反映在精细的风险评估中,特别是晚期慢性阻塞性肺疾病(COPD)、特发性肺纤维化(IPF)和肺动脉高压(PAH)患者。此外,有癌症病史和感染艾滋病毒或耐多药生物的患者的标准也变得更加灵活,从而导致更具包容性的移植政策。一个关键的重点是早期移植咨询,使患者有机会在急性恶化之前进行移植。这些更新的指南旨在通过差异化和风险调整决策,最大限度地提高移植患者的生存率和生活质量。
{"title":"[Indications for Lung Transplantation - Updates Since the Last ISHLT Recommendations].","authors":"Zsofia Kovacs, Alberto Benazzo, Peter Jaksch","doi":"10.1055/a-2563-3691","DOIUrl":"10.1055/a-2563-3691","url":null,"abstract":"<p><p>Lung transplantation has evolved continuously since its first successful procedures in the 1960 s. The current guidelines from the International Society for Heart and Lung Transplantation (ISHLT) emphasise increasingly individualised patient assessment, which, in addition to the underlying lung disease, considers factors such as comorbidities, frailty, age, and social aspects. The expanded indications for lung transplantation are reflected in the refined risk assessment, which particularly includes patients with advanced chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), and pulmonary arterial hypertension (PAH). Furthermore, the criteria for patients with a history of cancer and those with infections such as HIV or multidrug-resistant organisms have been made more flexible, leading to a more inclusive transplantation policy. A key focus is on early transplant counselling, allowing patients the opportunity for transplantation before they develop acute exacerbations. These updated guidelines aim to maximise both the survival rates and the quality of life of transplant patients, through differentiated and risk-adjusted decision-making.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":" ","pages":"256-260"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Hypertension and Lung Transplantation. 肺动脉高压与肺移植。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-06-01 Epub Date: 2025-05-14 DOI: 10.1055/a-2590-2620
Sophie Kruszona, Khalil Aburahma, Nunzio Davide de Manna, Dmitry Bobylev, Arjang Ruhparwar, Christian Kuehn, Jawad Salman, Fabio Ius

Pulmonary artery hypertension (PAH), a subtype of pulmonary hypertension, is a rare end-stage lung disease. Bilateral lung and combined heart and lung transplantation have long been considered as a gold standard therapy for PAH.This manuscript reviewed the most up-to-date literature on lung transplantation for PAH, focusing particularly on risk stratification, donor allocation, bridging to transplantation (BTT), and intra- and postoperative management in both adult and pediatric patients.The last two decades have witnessed an important shift in the transplant indications and strategy for PAH. Newly introduced antihypertensive drugs have postponed the time of transplantation in eligible patients, thus reserving transplantation for severely ill high-risk patients on triple antihypertensive therapy. Furthermore, the widespread peritransplant use of veno-arterial extracorporeal membrane oxygenation (ECMO) enables cardiac remodeling after bilateral lung transplantation.The change in transplant strategy from combined heart and lung transplantation to bilateral lung transplantation renders more organs available for transplantation in an era of organ shortage. ECMO-bridging is a life-saving tool in selected PAH patients although associated with higher complications. Better organ allocation in PAH patients at high risk of decompensation may reduce the need for ECMO-bridging and may further improve outcomes.

肺动脉高压(PAH)是肺动脉高压的一个亚型,是一种罕见的终末期肺部疾病。长期以来,双侧肺移植和心肺联合移植被认为是治疗PAH的金标准。这篇文章回顾了关于肺移植治疗多环芳烃的最新文献,特别关注风险分层、供体分配、移植桥接(BTT)以及成人和儿童患者的手术内和术后管理。过去二十年见证了PAH移植适应症和策略的重要转变。新推出的降压药物推迟了符合条件患者的移植时间,从而将移植留给了三重降压治疗的重症高危患者。此外,静脉-动脉体外膜氧合(ECMO)的广泛应用使双侧肺移植后的心脏重构成为可能。从心肺联合移植到双侧肺移植的移植策略的变化,使得在器官短缺的时代有更多的器官可供移植。ecmo桥接是一种挽救部分PAH患者生命的工具,尽管与较高的并发症相关。在失代偿高风险的PAH患者中,更好的器官分配可能减少ecmo桥接的需要,并可能进一步改善预后。
{"title":"Pulmonary Hypertension and Lung Transplantation.","authors":"Sophie Kruszona, Khalil Aburahma, Nunzio Davide de Manna, Dmitry Bobylev, Arjang Ruhparwar, Christian Kuehn, Jawad Salman, Fabio Ius","doi":"10.1055/a-2590-2620","DOIUrl":"10.1055/a-2590-2620","url":null,"abstract":"<p><p>Pulmonary artery hypertension (PAH), a subtype of pulmonary hypertension, is a rare end-stage lung disease. Bilateral lung and combined heart and lung transplantation have long been considered as a gold standard therapy for PAH.This manuscript reviewed the most up-to-date literature on lung transplantation for PAH, focusing particularly on risk stratification, donor allocation, bridging to transplantation (BTT), and intra- and postoperative management in both adult and pediatric patients.The last two decades have witnessed an important shift in the transplant indications and strategy for PAH. Newly introduced antihypertensive drugs have postponed the time of transplantation in eligible patients, thus reserving transplantation for severely ill high-risk patients on triple antihypertensive therapy. Furthermore, the widespread peritransplant use of veno-arterial extracorporeal membrane oxygenation (ECMO) enables cardiac remodeling after bilateral lung transplantation.The change in transplant strategy from combined heart and lung transplantation to bilateral lung transplantation renders more organs available for transplantation in an era of organ shortage. ECMO-bridging is a life-saving tool in selected PAH patients although associated with higher complications. Better organ allocation in PAH patients at high risk of decompensation may reduce the need for ECMO-bridging and may further improve outcomes.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":" ","pages":"273-285"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Extracorporeal Life Support in Lung Transplantation and Beyond]. 体外生命支持在肺移植及其他方面的应用。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-06-01 Epub Date: 2025-04-07 DOI: 10.1055/a-2563-8383
Alexander Hermann, Thomas Schweiger

Lung transplantation is often the sole and final therapeutic option for patients with end-stage lung disease. In recent years, clinical outcomes have steadily improved, driven in part by advancements in extracorporeal mechanical support. These techniques have become an integral component of routine clinical practice, particularly in lung transplantation centres. Extracorporeal lung support systems range from relatively simple pumpless devices to complex cannulation techniques and device configurations. In particular, extracorporeal membrane oxygenation (ECMO) encompasses various configurations widely utilised in thoracic surgery, especially in lung transplantation. A distinction can be made between preoperative ECMO, referred to as bridge-to-transplant, and intraoperative ECMO support, which is employed during the transplantation procedure. In recent years, intraoperative ECMO has largely replaced the traditional heart-lung machine. Additionally, ECMO plays a critical role in the immediate postoperative period, both in preventing and managing primary graft dysfunction. Beyond lung transplantation, extracorporeal life support systems are also applied in complex thoracic surgical resections and procedures involving the central airways. In the future, technical advancements and improvements in treatment protocols are expected to further enhance the role of extracorporeal mechanical support in the management of thoracic surgical patients.

肺移植通常是终末期肺病患者唯一和最后的治疗选择。近年来,临床结果稳步改善,部分原因是体外机械支持的进步。这些技术已成为常规临床实践的一个组成部分,特别是在肺移植中心。体外肺支持系统的范围从相对简单的无泵设备到复杂的插管技术和设备配置。特别是,体外膜氧合(ECMO)包括各种配置,广泛应用于胸外科,特别是肺移植。术前ECMO(称为移植桥)和术中ECMO支持(在移植过程中使用)是有区别的。近年来,术中ECMO已在很大程度上取代了传统的心肺机。此外,ECMO在术后立即预防和处理原发性移植物功能障碍方面起着关键作用。除了肺移植,体外生命支持系统也应用于复杂的胸外科手术切除和涉及中央气道的手术。在未来,技术的进步和治疗方案的改进有望进一步增强体外机械支持在胸外科患者管理中的作用。
{"title":"[Extracorporeal Life Support in Lung Transplantation and Beyond].","authors":"Alexander Hermann, Thomas Schweiger","doi":"10.1055/a-2563-8383","DOIUrl":"10.1055/a-2563-8383","url":null,"abstract":"<p><p>Lung transplantation is often the sole and final therapeutic option for patients with end-stage lung disease. In recent years, clinical outcomes have steadily improved, driven in part by advancements in extracorporeal mechanical support. These techniques have become an integral component of routine clinical practice, particularly in lung transplantation centres. Extracorporeal lung support systems range from relatively simple pumpless devices to complex cannulation techniques and device configurations. In particular, extracorporeal membrane oxygenation (ECMO) encompasses various configurations widely utilised in thoracic surgery, especially in lung transplantation. A distinction can be made between preoperative ECMO, referred to as bridge-to-transplant, and intraoperative ECMO support, which is employed during the transplantation procedure. In recent years, intraoperative ECMO has largely replaced the traditional heart-lung machine. Additionally, ECMO plays a critical role in the immediate postoperative period, both in preventing and managing primary graft dysfunction. Beyond lung transplantation, extracorporeal life support systems are also applied in complex thoracic surgical resections and procedures involving the central airways. In the future, technical advancements and improvements in treatment protocols are expected to further enhance the role of extracorporeal mechanical support in the management of thoracic surgical patients.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":" ","pages":"286-294"},"PeriodicalIF":0.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Zentralblatt fur Chirurgie
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1