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[Effect of loading angle and fabrication materials on stress distribution with periodontal splint in compromised periodontal tissues: a finite element study]. [加载角度和制作材料对受损牙周组织中牙周夹板应力分布的影响:有限元研究]。
Q4 Medicine Pub Date : 2024-11-09 DOI: 10.3760/cma.j.cn112144-20240712-00270
M Fang, Y C Liu, S Zhong, D M Li, T Yang, S Z Bai
<p><p><b>Objective:</b> To evaluate the effect of polyetheretherketone (PEEK) periodontal splints and splints made from other materials under static loading on stress distributions in periodontal tissues, cement layer, and splints themselves. <b>Methods:</b> A finite element model based on cone-beam CT imaging data of a 25-year-old male patient (treated at the Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University in October 2021 for a cracked maxillary molar) with a healthy and intact mandibular dentition and periodontal health was constructed. The finite element model included anterior mandible dentition, mandibular bone model without bone resorption (WBR group), a periodontally compromised mandible model (control group), and three types of periodontal splints: a PEEK periodontal splint (0.7 mm thick, Young's modulus: 4.1 MPa), a fiber-reinforced resin (FRC) splint (1.0 mm thick, Young's modulus: 37.0 MPa), and a titanium splint (1.2 mm thick, Young's modulus: 110.0 MPa). The bone resorption models fixed with different periodontal splints constituted the experimental groups (PEEK group, FRC group and titanium group). Loading of 100 N was applied on the midpoint of the incisal edge of tooth 41. The direction was set at 0°, which was parallel to the long axis of the tooth and downward. The buccal to lingual and downward angles were 30°and 60°, respectively, perpendicular to the long axis of the tooth and 90° to the lingual side. The finite element analysis software was utilized to analyze the stress distribution characteristics of the periodontal tissues, adhesive layer, and the splint itself in the anterior mandibular teeth among the different group. <b>Results:</b> Under the different loading simulation, in the control group, the maximal von Mises stresses of periodontal ligament and bone were 15.7-50.2 MPa and 38.8-130.3 MPa, respectively, and in the WBR group, the maximal von Mises stresses of periodontal ligament and bone were 3.6-6.4 MPa and 16.5-42.7 MPa, respectively. Under the same loading conditions, the magnitude of maximal von Mises stresses in periodontal tissues in the PEEK group was 4.6-6.2 MPa, and the magnitude of stresses in the periodontal ligament of 41 teeth in the WBR group was similar to that in the PEEK group, but higher than that in the FRC and titanium groups. The maximal von Mises stresses of each group is primarily distributed in the periodontal ligament and alveolar bone at the cervical area of the tooth. The higher the elastic modulus of the splint, the higher its own maximal von Mises stresses, and the smaller the maximal principal stresses transmitted to the adhesive layer. In the PEEK group and titanium group, the stress distribution area in the adhesive layer and the splint was near the splint connection adjacent to tooth 41. <b>Conclusions:</b> Periodontal splints fabricated from three types of materials, are effective in distributing stress within the periodontal tissues of
目的:评估聚醚醚酮(PEEK)牙周夹板和其他材料制成的夹板在静态负荷下对牙周组织、骨水泥层和夹板本身应力分布的影响。方法:以一名 25 岁男性患者(2021 年 10 月在第四军医大学口腔医学院口腔修复科接受上颌臼齿裂开治疗)的锥形束 CT 成像数据为基础,建立了一个下颌牙体和牙周健康完好的有限元模型。有限元模型包括下颌前牙、无骨吸收的下颌骨模型(WBR 组)、牙周受损的下颌骨模型(对照组)以及三种牙周夹板:PEEK 牙周夹板(0.7 毫米厚,杨氏模量:4.1 兆帕)、纤维增强树脂(FRC)夹板(1.0 毫米厚,杨氏模量:37.0 兆帕)和钛夹板(1.2 毫米厚,杨氏模量:110.0 兆帕)。用不同牙周夹板固定的骨吸收模型构成了实验组(PEEK 组、FRC 组和钛合金组)。在第 41 号牙齿切缘中点施加 100 牛顿的荷载。方向设定为 0°,与牙齿长轴平行并向下。颊舌角和向下角分别为 30°和 60°,与牙齿长轴垂直,与舌侧成 90°。利用有限元分析软件分析了不同组别下颌前牙牙周组织、粘接层和夹板本身的应力分布特征。结果在不同的加载模拟条件下,对照组牙周韧带和牙槽骨的最大 von Mises 应力分别为 15.7-50.2 兆帕和 38.8-130.3 兆帕,而 WBR 组牙周韧带和牙槽骨的最大 von Mises 应力分别为 3.6-6.4 兆帕和 16.5-42.7 兆帕。在相同的加载条件下,PEEK 组牙周组织的最大 von Mises 应力为 4.6-6.2 兆帕,WBR 组 41 颗牙齿牙周韧带的应力与 PEEK 组相似,但高于 FRC 组和钛组。各组的最大 von Mises 应力主要分布在牙颈部的牙周韧带和牙槽骨中。夹板的弹性模量越高,其自身的最大 von Mises 应力就越大,传递到粘接层的最大主应力就越小。在 PEEK 组和钛组中,粘合剂层和夹板的应力分布区位于邻近第 41 号牙齿的夹板连接处附近。结论由三种材料制成的牙周夹板能有效分散基牙牙周组织内的应力。与 FRC 和钛组相比,PEEK 夹板获得的应力值越高,传递到其粘接层的应力值越小。
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引用次数: 0
[Influence of operator's experience on the quality and success rate of root canal treatment with new nickel-titanium instruments]. [操作者的经验对使用新型镍钛器械进行根管治疗的质量和成功率的影响]。
Q4 Medicine Pub Date : 2024-11-09 DOI: 10.3760/cma.j.cn112144-20240516-00206
T F Shao, R Zhang, R Guan, C Zhang, B X Hou

Objective: To analyze the influence of operator's experience on the quality and success rate of root canal treatment with new nickel-titanium instruments, providing support for improving the success rate of root canal treatment with new nickel-titanium instruments in clinic. Methods: Cases of root canal treatment and non-surgical root canal retreatment with 6-12 months recall performed by residents (resident group) with experience of 1-3 years and endodontic specialists (specialist group) with experience of 5-7 years were collected from the electronic medical system of the Department of Endodontics, School of Stomatology, Capital Medical University, from September 2020 to August 2021. All cases were prepared by engine-driven glide path files and controlled memory nickel-titanium finishing files. Chi-square test and logistic regression were used to analyze the differences and influencing factors of complications, filling quality and success rate of root canal treatment between the two groups. Results: A total of 277 cases performed by 24 residents and 3 specialists were included, 169 in the resident group and 108 in the specialist group. The clinical incidence of flare-ups was significantly higher in the resident group [3.6% (6/169)] than in the specialist group [0(0/108)] (P=0.048). There were no significant differences in ledges, root canal transportations, perforations, or instrument separations between the two groups (P>0.05). The prevalence of satisfactory fillings was 62.7% (106/169) in the resident group, which was significantly lower than that in the specialist group [86.1% (93/108)] (P<0.05). The success rate of root canal treatment was 91.7% (155/169) and 94.4% (102/108) in the resident group and the specialist group, respectively, with no significant differences (χ2=0.73,P=0.392). Multivariate analysis showed that the success rate of root canal treatment was related to complications and quality of root fillings (P<0.05). Conclusions: Higher success rate of root canal treatment could be achieved by residents and endodontic specialists with engine-driven glide path files and controlled memory nickel-titanium files.

目的分析操作者经验对使用新型镍钛器械进行根管治疗的质量和成功率的影响,为提高临床使用新型镍钛器械进行根管治疗的成功率提供支持。方法:从首都医科大学口腔医学院牙体牙髓科电子医疗系统中收集 2020 年 9 月至 2021 年 8 月期间由具有 1-3 年工作经验的住院医师(住院医师组)和具有 5-7 年工作经验的牙体牙髓专科医师(专科医师组)实施的根管治疗和 6-12 个月召回的非手术根管再治疗病例。所有病例均使用发动机驱动的滑行牙弓和可控记忆镍钛精加工牙弓进行预备。采用卡方检验和逻辑回归分析两组根管治疗并发症、充填质量和成功率的差异及影响因素。结果24名住院医师和3名专科医生共完成了277例根管治疗,其中住院医师组169例,专科医生组108例。住院医师组的耀斑临床发生率[3.6%(6/169)]明显高于专科医生组[0(0/108)](P=0.048)。两组之间在根尖、根管运输、穿孔或器械分离方面没有明显差异(P>0.05)。住院医师组的满意充填率为 62.7%(106/169),明显低于专科医师组[86.1%(93/108)](P0.05)。住院医师组和专科医生组的根管治疗成功率分别为 91.7%(155/169)和 94.4%(102/108),差异无显著性(χ2=0.73,P=0.392)。多变量分析显示,根管治疗的成功率与并发症和根充质量有关(P0.05)。结论住院医师和牙髓专科医生使用发动机驱动的滑行路径根管针和可控记忆镍钛根管针可以获得更高的根管治疗成功率。
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引用次数: 0
[Influencing factors of implant accuracy of oral implant robot]. [口腔种植机器人种植精度的影响因素]。
Q4 Medicine Pub Date : 2024-11-09 DOI: 10.3760/cma.j.cn112144-20240405-00135
M M You, Z H Zhang

In recent years, robots have been gradually applied in the field of oral implantation. Compared with static guide and dynamic navigation, robot-assisted implant surgery has the characteristics of high precision, high stability and high safety, but there are still various factors affecting the accuracy of implantation in the operation process. Existing studies focus on the accuracy of robot-assisted oral implant surgery, while there are few studies on the image factors affecting the accuracy of robot-assisted oral implant surgery. Therefore, this paper analyzes the factors affecting the accuracy of robot-assisted oral implant surgery from the aspects of the type and operation of the implant robot, in order to provide evidence for the application of the implant robot in the field of oral implant.

近年来,机器人已逐渐应用于口腔种植领域。与静态引导和动态导航相比,机器人辅助种植手术具有高精度、高稳定性和高安全性的特点,但在操作过程中仍有各种因素影响着种植的准确性。现有研究主要集中在机器人辅助口腔种植手术的准确性方面,而对影响机器人辅助口腔种植手术准确性的影像因素研究较少。因此,本文从种植机器人的类型、操作等方面分析了影响机器人辅助口腔种植手术准确性的因素,以期为种植机器人在口腔种植领域的应用提供依据。
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引用次数: 0
[Research progress in the application of virtual artificial intelligence in risk assessment and diagnosis of periodontal disease]. [虚拟人工智能在牙周病风险评估和诊断中的应用研究进展]。
Q4 Medicine Pub Date : 2024-11-09 DOI: 10.3760/cma.j.cn112144-20240117-00027
W J Hong, C C Liu, Y Ding

Periodontal disease is a common and frequently-occurring disease in China. Early detection, diagnosis, and treatment of periodontal disease are of great significance for achieving universal oral health and even systemic health. Artificial intelligence endows machines with the ability to mimic human intelligent behavior, and is commonly used in medical field with both physical and virtual forms. Virtual artificial intelligence empowers traditional experience in the application of periodontal disease risk assessment and diagnosis, with the potential to develop a variety of oral health screening tools. It helps to provide new evidence for the prognosis of periodontal disease, improve the accuracy and efficiency of diagnosis, reduce technical sensitivity and further promote the periodontal treatment transformation from "treatment-oriented" to "prevention-oriented". This paper reviews the current applications and progresses of virtual artificial intelligence in periodontal risk assessment and diagnosis, as well as its limitations, providing ideas for future researches on the application of virtual artificial intelligence in this field.

牙周病是中国的常见病、多发病。牙周病的早发现、早诊断、早治疗,对实现全民口腔健康乃至全身健康具有重要意义。人工智能赋予机器模仿人类智能行为的能力,并以物理和虚拟两种形式普遍应用于医疗领域。虚拟人工智能赋予了传统经验在牙周病风险评估和诊断中的应用,有可能开发出多种口腔健康筛查工具。它有助于为牙周病的预后提供新的证据,提高诊断的准确性和效率,降低技术敏感性,进一步推动牙周治疗从 "治疗为主 "向 "预防为主 "转变。本文综述了虚拟人工智能在牙周风险评估与诊断中的应用现状、进展及其局限性,为今后虚拟人工智能在该领域的应用研究提供了思路。
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引用次数: 0
[Research of decision-making artificial intelligence for oral implantation]. [口腔种植决策人工智能研究]。
Q4 Medicine Pub Date : 2024-11-09 DOI: 10.3760/cma.j.cn112144-20240312-00109
Z T Chen, Z F Chen

The oral implant surgery robot could achieved basic "surgical operation intelligence"; however, "decision-making artificial intelligence" has not yet been achieved. The author previously discussed the specific concept of decision-making artificial intelligence. During our exploration of decision-making artificial intelligence, our team further integrated the clinical diagnosis and treatment process of oral implantation, along with the data characteristics of decision indicators and the distribution characteristics of demographic information. As a result, we identified five key scientific and technological issues in the process of decision-making artificial intelligence, namely the construction of a specialized annotation database for oral implantation, the prediction of quantitative indicators, the application of three-dimensional imaging, the solution of data imbalance within indicators, and the joint output of multi-property and multimodal indicators in clinical pathways. This paper will review artificial intelligence research in oral implantology and our team's research progress, elaborating on the aforementioned challenges in intelligentization. It aims to provide references for addressing the mentioned scientific issues and guiding future research directions in the construction of decision-making artificial intelligence in oral medicine.

口腔种植手术机器人可以实现基本的 "手术操作智能",但 "种植决策智能 "尚未实现。笔者此前曾讨论过种植决策人工智能的具体概念。在对种植决策智能的探索中,我们团队进一步结合口腔种植的临床诊疗过程,以及决策指标的数据特征和人口信息的分布特征。由此,我们发现了口腔种植决策智能过程中的五个关键科技问题,即口腔种植专业标注数据库的构建、定量指标的预测、三维成像的应用、指标内数据不平衡的解决以及临床路径中多属性、多模态指标的联合输出。本文将回顾口腔种植领域的人工智能研究和我们团队的研究进展,阐述上述智能化挑战。旨在为解决上述科学问题提供参考,指导未来口腔医学种植决策智能化建设的研究方向。
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引用次数: 0
[Customized lingual orthodontics: clinical features and difficulties]. [定制舌侧正畸:临床特点和困难]。
Q4 Medicine Pub Date : 2024-11-09 DOI: 10.3760/cma.j.cn112144-20240624-00247
N Zhang, B Fang, Y X Bai

Lingual orthodontic technology has been in existence for over 50 years, undergoing various stages of emergence, development, decline, and maturity. In recent years, with the advancement of digital technology, customized lingual orthodontics has gradually become widely used in clinical practice, representing a significant achievement of digital technology in orthodontic clinical diagnosis and treatment. The integration of digital technology has made customized lingual orthodontics more convenient, precise, and efficient, enhancing patient comfort while significantly reducing the operational difficulty and technical barriers for orthodontists. This article focuses on analyzing the technical characteristics, operational challenges, and coping strategies of customized lingual orthodontics based on digital technology, aiming to provide a reference for clinical practice.

舌侧正畸技术已有 50 多年的历史,经历了兴起、发展、衰落和成熟等不同阶段。近年来,随着数字化技术的发展,定制化舌侧正畸技术逐渐广泛应用于临床,代表了数字化技术在正畸临床诊疗中的重大成果。数字化技术的融入使定制化舌侧正畸更加便捷、精准、高效,在提高患者舒适度的同时,也大大降低了正畸医生的操作难度和技术壁垒。本文重点分析了基于数字化技术的定制化舌侧正畸的技术特点、操作难点及应对策略,旨在为临床实践提供参考。
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引用次数: 0
[Exploration and innovative application of digital technology in pediatric dentistry]. [数字技术在儿童牙科中的探索和创新应用]。
Q4 Medicine Pub Date : 2024-11-09 DOI: 10.3760/cma.j.cn112144-20240722-00284
Y J Zhao, X X Chen, J Wang, Y Wang

Pediatric dentistry treats patients aged 0-18 years, encompassing the characteristics of general dentistry. The clinical techniques are closely related to restorative dentistry, endodontics, orthodontics, and maxillofacial surgery, while also possessing unique aspects. It particularly focuses on the growth and development patterns of children's dentition and maxillofacial structures. Currently, digital technology has deeply integrated with various clinical disciplines of dentistry, and pediatric dentistry has made significant progress with pediatric-specific digital applications. On one hand, the introduction of mature digital technologies is enabling the digital transformation of pediatric dental treatment models; on the other hand, there is innovative development of new digital technologies tailored to the specific needs of pediatric dental care, filling gaps in the field. Based on years of research in digital technology for pediatric dentistry, our team details the current innovative applications and scientific explorations in this area from these two perspectives. Additionally, we anticipate the potential expansion of digital technologies not yet applied in pediatric dentistry, providing a reference for clinical scholars in the field to conduct exploratory research.

儿童牙科主要治疗 0-18 岁的患者,具有普通牙科的特点。其临床技术与修复牙科、牙体牙髓病学、正畸学和颌面外科密切相关,同时也有其独特之处。它尤其关注儿童牙齿和颌面结构的生长发育规律。目前,数字化技术已经与口腔医学的各个临床学科深度融合,儿童口腔医学在儿童专用数字化应用方面也取得了长足的进步。一方面,成熟数字技术的引入实现了儿童牙科治疗模式的数字化转型;另一方面,针对儿童牙科治疗的特殊需求,新的数字技术也在不断创新发展,填补了该领域的空白。基于多年来对儿童牙科数字技术的研究,我们的团队从这两个角度详细介绍了该领域当前的创新应用和科学探索。此外,我们还预计了尚未应用于儿童牙科的数字技术的潜在扩展,为该领域的临床学者开展探索性研究提供了参考。
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引用次数: 0
[Research on the method of digital technology assisted direct resin composite restoration for deep distal caries in mandibular second molars]. [数字化技术辅助下颌第二磨牙远端深龋直接树脂复合修复方法研究]。
Q4 Medicine Pub Date : 2024-11-09 DOI: 10.3760/cma.j.cn112144-20240709-00263
X Y Zhang, Y Wang, Z Q Pan, Y Y Liu, Y J Zhao

Objective: To explore the digital design and fabrication technology of personalized restorative matrix for dental filling, and to explore the feasibility of direct resin restoration for deep caries lesions in distal neck of mandibular second molar. Methods: For patients with deep caries lesions in the distal neck of the mandibular second molar who visited the Department of Cariology and Endodontology of Peking University School and Hospital of Stomatology from September 2023 to April 2024, after preparing the cavity and gingival retractor, a three-dimensional intraoral scanner was used to obtain three-dimensional data of the patient's dentition. In the dental restoration computer-aided design software, the inlay function was used to generate the restored tooth morphology. The edge range of the personalized restorative matrix was drawn on the restored model by three-dimensional reverse engineering software to achieve edge sealing effect. The selected edge range data was processed with distal shelling to generate a digital model of a personalized restorative matrix with a thickness of 0.5 mm. A metal three-dimensional printer was used to fabricate the titanium alloy restorative matrix, and its application was completed in 10 clinical cases. The marginal adaptation and retention stability of the personalized restorative matrix were evaluated under a dental microscope, and forming effect evaluation was performed through immediate postoperative periapical radiographs. Results: The preliminary clinical application of the personalized restorative matrix fabricated using digital technology revealed that, in the treatment of 10 affected teeth, rubber dam isolation was successfully ensured, resulting in clinically effective direct resin composite restorations with optimal marginal adaptation and reasonable contours. Immediate postoperative periapical radiographs showed good convexity of the filling body, with no overhangs found. Both marginal adaptation and retention stability met the requirements of clinical treatment. Conclusions: The personalized restorative matrix designed in this study can solve the clinical problems of moisture separation and resin forming in the treatment of deep caries lesions in distal neck of the mandibular second molar, and can achieve stable and reliable adhesive restoration effects.

目的探索个性化补牙修复基质的数字化设计与制作技术,探讨树脂直接修复下颌第二磨牙远端颈部深龋病变的可行性。研究方法对2023年9月至2024年4月在北京大学口腔医学院附属北京大学口腔医院龋病与牙髓病科就诊的下颌第二磨牙远端颈部深龋病变患者,在制备牙洞和牙龈牵引器后,使用三维口内扫描仪获取患者牙体的三维数据。在牙科修复计算机辅助设计软件中,使用嵌体功能生成修复后的牙齿形态。通过三维逆向工程软件在修复模型上绘制个性化修复基质的边缘范围,以达到边缘封闭的效果。选取的边缘范围数据经过远端脱壳处理,生成厚度为 0.5 毫米的个性化修复基质数字模型。使用金属三维打印机制作了钛合金修复基台,并在10个临床病例中完成了应用。在牙科显微镜下对个性化修复体的边缘适应性和固位稳定性进行了评估,并通过术后即刻根尖周X光片对成形效果进行了评估。结果利用数字化技术制作的个性化修复体的初步临床应用表明,在对 10 颗患牙的治疗中,成功地确保了橡胶坝的隔离,从而获得了临床上有效的直接树脂复合修复体,并具有最佳的边缘适应性和合理的轮廓。术后即刻的根尖周X光片显示充填体的凸度良好,没有发现悬突。边缘适应性和固位稳定性均符合临床治疗的要求。结论本研究设计的个性化修复基质可以解决下颌第二磨牙远端颈部深龋病变治疗中的水分分离和树脂成型等临床问题,并能达到稳定可靠的粘接修复效果。
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引用次数: 0
[Complete denture rehabilitation for an aged patient with Parkinson disease: a case report]. [帕金森病老年患者的全口义齿修复:病例报告]。
Q4 Medicine Pub Date : 2024-10-09 DOI: 10.3760/cma.j.cn112144-20240410-00145
J Y Huo, P Y You, C L Guo, K Wan
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引用次数: 0
[Experts consensus on standard items of the cohort construction and quality control of temporomandibular joint diseases (2024)]. [颞下颌关节疾病队列建设和质量控制标准项目专家共识(2024 年)]。
Q4 Medicine Pub Date : 2024-10-09 DOI: 10.3760/cma.j.cn112144-20240725-00293
M Hu, C Yang, H H Liu, H X Lu, C Yao, Q F Xie, Y J Chen, K Y Fu, B Fang, S S Zhu, Q Zhou, Z Y Chen, Y M Zhu, Q B Zhang, Y Yan, X Long, Z Y Li, Y H Gan, S B Yu, Y X Bai, Y Zhang, Y Y Wang, J Lei, Y Cheng, C K Liu, Y Cao, D M He, N Wen, S Y Zhang, M J Chen, G L Jiao, X H Liu, H Jiang, Y He, P Shen, H T Huang, Y F Li, J S Zheng, J Guo, L S Zhao, L Q Xu

Temporomandibular joint (TMJ) diseases are common clinical conditions. The number of patients with TMJ diseases is large, and the etiology, epidemiology, disease spectrum, and treatment of the disease remain controversial and unknown. To understand and master the current situation of the occurrence, development and prevention of TMJ diseases, as well as to identify the patterns in etiology, incidence, drug sensitivity, and prognosis is crucial for alleviating patients'suffering.This will facilitate in-depth medical research, effective disease prevention measures, and the formulation of corresponding health policies. Cohort construction and research has an irreplaceable role in precise disease prevention and significant improvement in diagnosis and treatment levels. Large-scale cohort studies are needed to explore the relationship between potential risk factors and outcomes of TMJ diseases, and to observe disease prognoses through long-term follw-ups. The consensus aims to establish a standard conceptual frame work for a cohort study on patients with TMJ disease while providing ideas for cohort data standards to this condition. TMJ disease cohort data consists of both common data standards applicable to all specific disease cohorts as well as disease-specific data standards. Common data were available for each specific disease cohort. By integrating different cohort research resources, standard problems or study variables can be unified. Long-term follow-up can be performed using consistent definitions and criteria across different projects for better core data collection. It is hoped that this consensus will be facilitate the development cohort studies of TMJ diseases.

颞下颌关节(TMJ)疾病是临床常见病。颞下颌关节疾病患者人数众多,其病因、流行病学、疾病谱和治疗方法仍存在争议和未知。了解和掌握颞下颌关节疾病的发生、发展和预防现状,找出病因、发病、药物敏感性和预后的规律,对于减轻患者的痛苦至关重要。队列的构建和研究对于疾病的精准预防和诊疗水平的显著提高具有不可替代的作用。需要开展大规模队列研究,探讨颞下颌关节疾病潜在危险因素与疾病结局之间的关系,并通过长期随访观察疾病预后。该共识旨在为颞下颌关节疾病患者的队列研究建立一个标准的概念框架,同时为该疾病的队列数据标准提供思路。颞下颌关节疾病队列数据既包括适用于所有特定疾病队列的通用数据标准,也包括特定疾病的数据标准。每个特定疾病队列都有通用数据。通过整合不同的队列研究资源,可以统一标准问题或研究变量。不同项目之间可以使用一致的定义和标准进行长期随访,从而更好地收集核心数据。希望这一共识能促进颞下颌关节疾病队列研究的发展。
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引用次数: 0
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中华口腔医学杂志
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