首页 > 最新文献

中华口腔医学杂志最新文献

英文 中文
[Expert consensus on the application of artificial intelligence in stomatology]. 【人工智能在口腔医学中的应用专家共识】。
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20251017-00413
Y Wei, Y J Wu, J J Deng, W Y Yu, Z T Chen, Y Fan, M M Xu, Q Yuan, C C Zhou, Z J Shang, L L Chen, X D Zhou, X L Deng

In recent years, artificial intelligence (AI) has rapidly advanced in the field of oral medicine, with applications extending across disease screening, diagnosis assistance, treatment planning, prognosis prediction, and dental education. Powered by deep learning and multimodal analytics, AI can efficiently integrate data from cone beam CT, intraoral scans, and electronic health records, enhancing precision and efficiency in managing dental caries, endodontic and periodontal diseases, oral mucosal lesions, and maxillofacial trauma. AI also contributes to omics research, biomaterial development, and laboratory automation, accelerating translational progress from basic science to clinical practice. Despite these advances, challenges such as lack of standardized data governance, limited model interpretability, privacy and security risks, and insufficient clinical validation and regulatory frameworks still remain. This expert consensus provides a comprehensive overview of AI applications in dentistry, outlines core technical pathways, and proposes recommendations related to data governance, platform development, ethics, and regulatory requirements. It aims to provide practical and unified guidance for dental practitioners, healthcare institutions, researchers, and industry stakeholders, promoting safe, standardized, and sustainable development of AI in oral healthcare.

近年来,人工智能(AI)在口腔医学领域迅速发展,应用范围涵盖疾病筛查、诊断辅助、治疗计划、预后预测和牙科教育。在深度学习和多模式分析的支持下,人工智能可以有效地整合来自锥形束CT、口腔内扫描和电子健康记录的数据,提高龋齿、牙髓和牙周病、口腔黏膜病变和颌面创伤管理的精度和效率。人工智能还有助于组学研究、生物材料开发和实验室自动化,加速从基础科学到临床实践的转化进程。尽管取得了这些进展,但缺乏标准化数据治理、模型可解释性有限、隐私和安全风险、临床验证和监管框架不足等挑战仍然存在。这份专家共识提供了人工智能在牙科领域应用的全面概述,概述了核心技术途径,并提出了与数据治理、平台开发、道德和监管要求相关的建议。旨在为牙科从业者、医疗机构、研究人员和行业利益相关者提供实用、统一的指导,促进人工智能在口腔医疗领域的安全、规范、可持续发展。
{"title":"[Expert consensus on the application of artificial intelligence in stomatology].","authors":"Y Wei, Y J Wu, J J Deng, W Y Yu, Z T Chen, Y Fan, M M Xu, Q Yuan, C C Zhou, Z J Shang, L L Chen, X D Zhou, X L Deng","doi":"10.3760/cma.j.cn112144-20251017-00413","DOIUrl":"10.3760/cma.j.cn112144-20251017-00413","url":null,"abstract":"<p><p>In recent years, artificial intelligence (AI) has rapidly advanced in the field of oral medicine, with applications extending across disease screening, diagnosis assistance, treatment planning, prognosis prediction, and dental education. Powered by deep learning and multimodal analytics, AI can efficiently integrate data from cone beam CT, intraoral scans, and electronic health records, enhancing precision and efficiency in managing dental caries, endodontic and periodontal diseases, oral mucosal lesions, and maxillofacial trauma. AI also contributes to omics research, biomaterial development, and laboratory automation, accelerating translational progress from basic science to clinical practice. Despite these advances, challenges such as lack of standardized data governance, limited model interpretability, privacy and security risks, and insufficient clinical validation and regulatory frameworks still remain. This expert consensus provides a comprehensive overview of AI applications in dentistry, outlines core technical pathways, and proposes recommendations related to data governance, platform development, ethics, and regulatory requirements. It aims to provide practical and unified guidance for dental practitioners, healthcare institutions, researchers, and industry stakeholders, promoting safe, standardized, and sustainable development of AI in oral healthcare.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"151-161"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Construction of distinctive exhibitions and narrative innovation in specialized medical museums: an analysis based on the construction practices of three dental museums]. 【专业医学博物馆特色展区建设与叙事创新:基于三家牙科博物馆建设实践的分析】
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20260105-00005
J Zhou, X Y Gu, S L Wang

To explore how specialized medical museums can break through homogenization on exhibition and construct Chinese narratives within the modern medical system, this study takes the International Museum of Stomatology, the West China Museum of Stomatology (formerly the Museum of Chinese Stomatology), and the Museum of the History of Chinese Stomatology as research objects to examine their exhibition construction and narrative practices based on field investigations, interviews, and document analysis. The study finds that, relying on disciplinary traditions and accumulated research resources, the three museums have formed three distinctive development models: internationalized collections focusing on contemporary disciplinary history, generative collections originating from teaching and clinical practices, and interpretive collections driven by interdisciplinary researches. At the narrative level, by embedding Chinese stomatological practice within global disciplinary lineages, national historical processes, and dialogues between ancient and modern medical knowledge, these museums avoid an interpretive framework based on a binary opposition between China and the West, and effectively present the contributions of Chinese stomatology within the global system of modern medicine. The construction of stomatology museums reflects the disciplinary self-awareness of the stomatological community in deeply integrating medical humanities and disciplinary history education into professional training, and has also become an important driving force for the development of related museums and the innovation of their narratives.

为探索专业医学博物馆如何在现代医疗体系中突破展览的同质化,构建中国叙事,本研究以国际口腔博物馆、华西口腔博物馆(原中国口腔博物馆)和中国口腔历史博物馆为研究对象,通过实地调查、访谈、研究、研究等方法,考察了它们的展览建设和叙事实践。还有文件分析。研究发现,三家博物馆依托学科传统和积累的研究资源,形成了聚焦当代学科历史的国际化馆藏、源自教学和临床实践的生成性馆藏和跨学科研究驱动的解释性馆藏三种特色鲜明的发展模式。在叙事层面,通过将中国口腔医学实践嵌入全球学科谱系、国家历史进程和古今医学知识对话中,这些博物馆避免了基于中国和西方二元对立的解释框架,并有效地展示了中国口腔医学在全球现代医学体系中的贡献。口腔博物馆的建设体现了口腔学界将医学人文、学科历史教育深度融入专业培养的学科自我意识,也成为相关博物馆发展和叙事创新的重要动力。
{"title":"[Construction of distinctive exhibitions and narrative innovation in specialized medical museums: an analysis based on the construction practices of three dental museums].","authors":"J Zhou, X Y Gu, S L Wang","doi":"10.3760/cma.j.cn112144-20260105-00005","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20260105-00005","url":null,"abstract":"<p><p>To explore how specialized medical museums can break through homogenization on exhibition and construct Chinese narratives within the modern medical system, this study takes the International Museum of Stomatology, the West China Museum of Stomatology (formerly the Museum of Chinese Stomatology), and the Museum of the History of Chinese Stomatology as research objects to examine their exhibition construction and narrative practices based on field investigations, interviews, and document analysis. The study finds that, relying on disciplinary traditions and accumulated research resources, the three museums have formed three distinctive development models: internationalized collections focusing on contemporary disciplinary history, generative collections originating from teaching and clinical practices, and interpretive collections driven by interdisciplinary researches. At the narrative level, by embedding Chinese stomatological practice within global disciplinary lineages, national historical processes, and dialogues between ancient and modern medical knowledge, these museums avoid an interpretive framework based on a binary opposition between China and the West, and effectively present the contributions of Chinese stomatology within the global system of modern medicine. The construction of stomatology museums reflects the disciplinary self-awareness of the stomatological community in deeply integrating medical humanities and disciplinary history education into professional training, and has also become an important driving force for the development of related museums and the innovation of their narratives.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"172-178"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A historical review of Shanghai Dental College]. [上海牙科专科学校历史回顾]。
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20251201-00478
Y H Shan, Y S Zhou, Q Chen, D Q Zhang, C B Guo

Since the introduction of modern Western medicine to China, Chinese medical education, including dental education, had undergone profound changes, gradually shifting from the traditional family inheritance or apprenticeship model to the modern medical school education system. Chinese dentists actively engaged in educational practice, and successively established 8 dental schools during modern times (1909-1949). Among them, Shanghai Dental College, as the only institution successfully registered with the education department and continued to operate after the founding of People's Republic of China, held a special historical position. Currently, systematic research on the background and process of its establishment is still insufficient. This article reviews the background of the establishment and development process of Shanghai Dental College, focusing on the school construction process, facilities, course system, teachers and student training, to better understand the efforts of modern Chinese dentists in promoting dental education, and enrich the historical research of stomatology.

自现代西医传入中国以来,中国的医学教育,包括牙科教育,发生了深刻的变化,逐渐从传统的家族传承或学徒模式转向现代医学学校教育体系。中国牙医积极从事教育实践,近代(1909-1949)先后建立了8所牙科学校。其中,上海牙科专科学校作为新中国成立后唯一一所成功在教育部注册并继续办学的院校,具有特殊的历史地位。目前,对其建立的背景和过程还缺乏系统的研究。本文回顾了上海口腔专科学校的建立和发展历程,重点介绍了学校的建设过程、设施、课程体系、教师和学生培养等方面的情况,以更好地了解中国现代牙医在推动口腔教育方面所做的努力,丰富口腔医学的历史研究。
{"title":"[A historical review of Shanghai Dental College].","authors":"Y H Shan, Y S Zhou, Q Chen, D Q Zhang, C B Guo","doi":"10.3760/cma.j.cn112144-20251201-00478","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20251201-00478","url":null,"abstract":"<p><p>Since the introduction of modern Western medicine to China, Chinese medical education, including dental education, had undergone profound changes, gradually shifting from the traditional family inheritance or apprenticeship model to the modern medical school education system. Chinese dentists actively engaged in educational practice, and successively established 8 dental schools during modern times (1909-1949). Among them, Shanghai Dental College, as the only institution successfully registered with the education department and continued to operate after the founding of People's Republic of China, held a special historical position. Currently, systematic research on the background and process of its establishment is still insufficient. This article reviews the background of the establishment and development process of Shanghai Dental College, focusing on the school construction process, facilities, course system, teachers and student training, to better understand the efforts of modern Chinese dentists in promoting dental education, and enrich the historical research of stomatology.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"209-213"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Advances in the application of body image intervention strategies for oral cancer patients under smart healthcare]. 【智慧医疗下口腔癌患者身体形象干预策略应用研究进展】。
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20250624-00233
X H Wang, Z Wang, N Zhao, L N Wei, K Q Yang

Oral cancer is a highly prevalent malignant tumor of the head and neck region worldwide. Patients often experience body image distress due to visible facial scarring and oral dysfunction. The advancement of smart healthcare technologies has provided innovative intervention strategies for body image rehabilitation in oral cancer patients. This study reviews and synthesizes global literature to systematically analyze the types, applications, and recommendations of body image intervention strategies for oral cancer patients in the context of smart healthcare. Current limitations and future directions are discussed.with the aim of supporting smart rehabilitation for patients and offering insights for the digital transformation of oral health care.

口腔癌是一种在世界范围内高度流行的头颈部恶性肿瘤。由于明显的面部疤痕和口腔功能障碍,患者经常经历身体形象困扰。智能医疗技术的进步为口腔癌患者的身体形象康复提供了创新的干预策略。本研究回顾并综合全球文献,系统分析智能医疗背景下口腔癌患者身体形象干预策略的类型、应用和建议。讨论了当前的局限性和未来的发展方向。旨在支持患者的智能康复,并为口腔卫生保健的数字化转型提供见解。
{"title":"[Advances in the application of body image intervention strategies for oral cancer patients under smart healthcare].","authors":"X H Wang, Z Wang, N Zhao, L N Wei, K Q Yang","doi":"10.3760/cma.j.cn112144-20250624-00233","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250624-00233","url":null,"abstract":"<p><p>Oral cancer is a highly prevalent malignant tumor of the head and neck region worldwide. Patients often experience body image distress due to visible facial scarring and oral dysfunction. The advancement of smart healthcare technologies has provided innovative intervention strategies for body image rehabilitation in oral cancer patients. This study reviews and synthesizes global literature to systematically analyze the types, applications, and recommendations of body image intervention strategies for oral cancer patients in the context of smart healthcare. Current limitations and future directions are discussed.with the aim of supporting smart rehabilitation for patients and offering insights for the digital transformation of oral health care.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"281-285"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[International publication trends and hotspots of clinical oral implantology research in China]. 【国内口腔种植临床研究国际出版物动态及热点】。
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20250609-00213
C B Li, S Q Bao, R Zhang, H K Luo, M S Si

Objective: To analyze the current status, trends and research hotspots of clinical research on oral implantology published in international journals by scholars from China(excluding Hong Kong, Macao, and Taiwan), and to provide insights into research dynamics for scholars and institutions in related fields. Methods: Based on Web of Science Core Collection, 460 documents were screened. Bibliometric analysis was performed using CiteSpace, and institutional collaboration network, keyword co-occurrence mapping and time zone view of burst words were drawn to explore the characteristics of publications, research hotspots and frontiers. Results: The number of Chinese oral implantology clinical research publications increased year by year, and institutions such as Peking University and Shanghai Jiao Tong University were the core contributors. Research hotspots focus on bone augmentation techniques (e.g., bone regeneration, maxillary sinus lift) and immediate implantation, and the frontier direction is dynamic navigation and robot-assisted surgery. The research areas are mainly in dentistry and oral surgery, with notable interdisciplinary integration. The percentage of high-impact journals was significant. Conclusions: The bibliometric study visualized the hotspots of clinical research in the field of oral implantation published by Chinese scholars in international journals. Future efforts should focus on improving the evidence system by large-sample multicenter studies and strengthen the collaboration between teams to promote the development of the discipline.

目的:分析中国(不含港澳台地区)学者在国际期刊上发表的口腔种植临床研究现状、趋势及研究热点,为相关领域的学者和机构了解研究动态提供参考。方法:基于Web of Science核心馆藏,筛选460篇文献。利用CiteSpace进行文献计量分析,绘制机构协作网络、关键词共现图和突发词时区视图,探索出版物特征、研究热点和前沿。结果:我国口腔种植临床研究论文数量逐年增加,以北京大学、上海交通大学等院校为主。研究热点集中在骨增强技术(如骨再生、上颌窦提升)和即刻种植,前沿方向是动态导航和机器人辅助手术。研究领域以牙科和口腔外科为主,跨学科融合显著。高影响力期刊的比例非常显著。结论:文献计量学研究可视化了我国学者在国际期刊上发表的口腔种植领域临床研究热点。今后应注重通过大样本多中心研究完善证据体系,加强团队合作,促进学科发展。
{"title":"[International publication trends and hotspots of clinical oral implantology research in China].","authors":"C B Li, S Q Bao, R Zhang, H K Luo, M S Si","doi":"10.3760/cma.j.cn112144-20250609-00213","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250609-00213","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the current status, trends and research hotspots of clinical research on oral implantology published in international journals by scholars from China(excluding Hong Kong, Macao, and Taiwan), and to provide insights into research dynamics for scholars and institutions in related fields. <b>Methods:</b> Based on Web of Science Core Collection, 460 documents were screened. Bibliometric analysis was performed using CiteSpace, and institutional collaboration network, keyword co-occurrence mapping and time zone view of burst words were drawn to explore the characteristics of publications, research hotspots and frontiers. <b>Results:</b> The number of Chinese oral implantology clinical research publications increased year by year, and institutions such as Peking University and Shanghai Jiao Tong University were the core contributors. Research hotspots focus on bone augmentation techniques (e.g., bone regeneration, maxillary sinus lift) and immediate implantation, and the frontier direction is dynamic navigation and robot-assisted surgery. The research areas are mainly in dentistry and oral surgery, with notable interdisciplinary integration. The percentage of high-impact journals was significant. <b>Conclusions:</b> The bibliometric study visualized the hotspots of clinical research in the field of oral implantation published by Chinese scholars in international journals. Future efforts should focus on improving the evidence system by large-sample multicenter studies and strengthen the collaboration between teams to promote the development of the discipline.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"220-228"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Principles and paradigms of augmented reality in oral implant surgery]. [增强现实在口腔种植手术中的原理和范例]。
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20250930-00387
T R Tian, X X Cai, Y Man

Augmented reality (AR) technology has the potential to fundamentally address the hand-eye coordination challenges inherent in dental navigation systems, and further, to revolutionize the way surgeons perceive and process clinical information during surgical procedures. However, current AR applications remain largely confined to simple interactions with imaging data, with little evidence of domain-specific hardware or generalized AR paradigms. More importantly, there is still a lack of discussion on how surgeons cognitively interpret AR-based virtual information. This gap has hindered efforts to design AR applications that are aligned with surgical cognitive processes, thereby limiting the full clinical value of AR in oral implant surgery. This paper reviews recent developments in AR across relevant disciplines, attempts to classify the underlying logic of AR interaction, and drawing on our team's research and development over the past several years, proposes a technical paradigm for AR applications with the potential for large-scale clinical adoption. The paradigm is based on a 'spatially anchored virtual indicators' that binds purely virtual guidance cues directly to the surgical field, enabling an intuitive, low-cognitive-load, and clinically scalable form of intraoperative navigation beyond conventional model-based AR approaches.

增强现实(AR)技术有可能从根本上解决牙科导航系统固有的手眼协调挑战,并进一步革新外科医生在手术过程中感知和处理临床信息的方式。然而,目前的AR应用仍然主要局限于与成像数据的简单交互,很少有领域特定硬件或通用AR范例的证据。更重要的是,关于外科医生如何在认知上解释基于ar的虚拟信息,仍然缺乏讨论。这一差距阻碍了设计与手术认知过程一致的AR应用的努力,从而限制了AR在口腔种植手术中的全部临床价值。本文回顾了AR相关学科的最新发展,试图对AR交互的潜在逻辑进行分类,并借鉴我们团队过去几年的研究和开发,提出了一种具有大规模临床应用潜力的AR应用技术范式。该范例基于“空间锚定虚拟指示器”,将纯虚拟引导线索直接绑定到手术领域,实现了一种直观、低认知负荷、临床可扩展的术中导航形式,超越了传统的基于模型的AR方法。
{"title":"[Principles and paradigms of augmented reality in oral implant surgery].","authors":"T R Tian, X X Cai, Y Man","doi":"10.3760/cma.j.cn112144-20250930-00387","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250930-00387","url":null,"abstract":"<p><p>Augmented reality (AR) technology has the potential to fundamentally address the hand-eye coordination challenges inherent in dental navigation systems, and further, to revolutionize the way surgeons perceive and process clinical information during surgical procedures. However, current AR applications remain largely confined to simple interactions with imaging data, with little evidence of domain-specific hardware or generalized AR paradigms. More importantly, there is still a lack of discussion on how surgeons cognitively interpret AR-based virtual information. This gap has hindered efforts to design AR applications that are aligned with surgical cognitive processes, thereby limiting the full clinical value of AR in oral implant surgery. This paper reviews recent developments in AR across relevant disciplines, attempts to classify the underlying logic of AR interaction, and drawing on our team's research and development over the past several years, proposes a technical paradigm for AR applications with the potential for large-scale clinical adoption. The paradigm is based on a 'spatially anchored virtual indicators' that binds purely virtual guidance cues directly to the surgical field, enabling an intuitive, low-cognitive-load, and clinically scalable form of intraoperative navigation beyond conventional model-based AR approaches.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"162-171"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Research status and prospect of orthodontically induced inflammatory root resorption]. 正畸诱导炎症根吸收的研究现状与展望
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20250807-00306
J L Chen, Y Yan, J R Li, T T Lan, W W Ma

Orthodontically induced inflammatory root resorption (OIIRR) is one of the most common and troublesome complications in orthodontic treatment, which not only affects the long-term stability of teeth, but also can cause irreversible damage to the patient's oral health. In light of the rising demand for orthodontic treatment, the prevention and treatment of OIIRR has become a primary focus for clinicians and researchers. Recent multidisciplinary studies have revealed the complex regulatory network of OIIRR, including mechanical signal transduction, immune microenvironment remodelling, cell differentiation pattern transformation and hard tissue matrix-specific regulation. Concurrently, targeted intervention strategies that have been developed based on these mechanisms have demonstrated favourable clinical application prospects. The present article systematically reviewed the clinical characteristics, influencing factors, molecular mechanisms and the latest clinical intervention strategies of OIIRR.

正畸诱导炎症性牙根吸收(OIIRR)是正畸治疗中最常见和最麻烦的并发症之一,不仅影响牙齿的长期稳定性,而且会对患者的口腔健康造成不可逆转的损害。鉴于对正畸治疗的需求不断增加,预防和治疗OIIRR已成为临床医生和研究人员关注的主要焦点。近年来的多学科研究揭示了OIIRR复杂的调控网络,包括机械信号转导、免疫微环境重塑、细胞分化模式转化和硬组织基质特异性调控。同时,基于这些机制开发的针对性干预策略已显示出良好的临床应用前景。本文系统综述了OIIRR的临床特点、影响因素、分子机制及最新的临床干预策略。
{"title":"[Research status and prospect of orthodontically induced inflammatory root resorption].","authors":"J L Chen, Y Yan, J R Li, T T Lan, W W Ma","doi":"10.3760/cma.j.cn112144-20250807-00306","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250807-00306","url":null,"abstract":"<p><p>Orthodontically induced inflammatory root resorption (OIIRR) is one of the most common and troublesome complications in orthodontic treatment, which not only affects the long-term stability of teeth, but also can cause irreversible damage to the patient's oral health. In light of the rising demand for orthodontic treatment, the prevention and treatment of OIIRR has become a primary focus for clinicians and researchers. Recent multidisciplinary studies have revealed the complex regulatory network of OIIRR, including mechanical signal transduction, immune microenvironment remodelling, cell differentiation pattern transformation and hard tissue matrix-specific regulation. Concurrently, targeted intervention strategies that have been developed based on these mechanisms have demonstrated favourable clinical application prospects. The present article systematically reviewed the clinical characteristics, influencing factors, molecular mechanisms and the latest clinical intervention strategies of OIIRR.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"273-280"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Chinese dentists in the War to Resist US Aggression and Aid Korea]. 【抗美援朝战争中的中国牙医】。
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20251205-00489
G Li, Z Y Yang, L Tian, G W Li, Q Zhou, Y J Xu, J Zhou, F L Chen, X D Zhou

This article reviews the history of the treatment of oral and maxillofacial injuries during the War to Resist US Aggression and Aid Korea from three aspects: dental medical services in the Korean battlefield, oral and maxillofacial plastic surgery in the rear treatment bases in Northeast China, and oral medical services in rear bases across the country. It shows that Chinese dentists were not afraid of sacrifice or difficulties, and had contributed their lives and wisdom to the oral health of Chinese and Korean military and civilians during the War to Resist US Aggression and Aid Korea, as well as to the cause of world peace. Their spirit is the traditions of revolution of the development of China's dental medicine industry.

本文从朝鲜战场的口腔医疗、东北后方治疗基地的口腔颌面整形、全国后方基地的口腔医疗三个方面对抗美援朝战争期间口腔颌面损伤的治疗历史进行了综述。这表明中国牙医不畏牺牲,不怕困难,在抗美援朝战争中为中国和朝鲜军民的口腔健康,为世界和平事业贡献了自己的生命和智慧。他们的精神是中国口腔医药产业发展的革命传统。
{"title":"[Chinese dentists in the War to Resist US Aggression and Aid Korea].","authors":"G Li, Z Y Yang, L Tian, G W Li, Q Zhou, Y J Xu, J Zhou, F L Chen, X D Zhou","doi":"10.3760/cma.j.cn112144-20251205-00489","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20251205-00489","url":null,"abstract":"<p><p>This article reviews the history of the treatment of oral and maxillofacial injuries during the War to Resist US Aggression and Aid Korea from three aspects: dental medical services in the Korean battlefield, oral and maxillofacial plastic surgery in the rear treatment bases in Northeast China, and oral medical services in rear bases across the country. It shows that Chinese dentists were not afraid of sacrifice or difficulties, and had contributed their lives and wisdom to the oral health of Chinese and Korean military and civilians during the War to Resist US Aggression and Aid Korea, as well as to the cause of world peace. Their spirit is the traditions of revolution of the development of China's dental medicine industry.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"214-219"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[In vitro study on the osteogenic potential of sulfonated and osteogenic growth peptide co-modified carbon fiber-reinforced polyetheretherketone]. [磺化与成骨生长肽共改性碳纤维增强聚醚醚酮成骨潜能的体外研究]。
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20250923-00375
Y X Lin, S Q Wang, Y Z Lai, J J Su
<p><p><b>Objective:</b> To determine an optimal surface modification protocol for carbon fiber-reinforced polyether ether ketone (CFR-PEEK), this study investigated the enhancement of material bioactivity and osteogenic properties. This was achieved by constructing a porous structure via sulfonation and polydopamine (PDA) modification and subsequently grafting osteogenic growth peptides (OGP) onto the surface. <b>Methods:</b> Using CFR-PEEK as the control group, CFR-PEEK specimens were sequentially subjected to 6 minute of sulfonation, hydrothermal treatment (SPK group), and PDA modification (SPD group), followed by grafting with 25, 50, or 100 μg/ml OGP (SPO25, SPO50, SPO100 groups). Surface morphology, functional groups, elemental composition, and hydrophilicity of each test specimen group were analyzed using scanning electron microscopy (SEM), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), and contact angle testing. Mouse osteoprogenitor cells (MC3T3-E1) were cultured on the surfaces of each group. Cell adhesion, proliferation, and osteogenic differentiation capabilities were evaluated through cell proliferation assays, immunofluorescence staining, alkaline phosphatase (ALP) and alizarin red staining, quantitative analysis, and real-time fluorescence quantitative PCR (RT-qPCR). <b>Results:</b> SEM revealed that the surface of the specimens formed a uniform three-dimensional porous structure after sulfonation treatment. ATR-FTIR and XPS revealed distinct characteristic peaks in the SPD and SPO groups; contact angle measurements demonstrated significantly superior hydrophilicity in all SPO groups compared to CFR-PEEK and SPK, with SPO50 group exhibiting optimal hydrophilicity (surface contact angle: 35.3°±2.5°), showing statistically significant differences from other groups (all <i>P</i><0.05). Cell proliferation assays demonstrated no cytotoxicity in the SPK, SPD, and SPO groups, with all significantly promoting cell proliferation (compared to CFR-PEEK). Among these, the SPO50 group exhibited significantly higher cell proliferation (1.365±0.049) on day 5 than other groups (<i>P</i><0.05), showing the best efficacy. SPK and SPD groups exhibited good cell spreading, while SPO groups (especially SPO50 and SPO100) demonstrated optimal cell adhesion properties. ALP staining and alizarin red staining results, along with their quantitative analysis, revealed that the SPO50 group exhibited the deepest ALP staining at both 7 and 14 d of osteogenic induction, and also demonstrated the deepest alizarin red staining at 14 days. Correspondingly, its 14-day ALP activity (0.057±0.001) and alizarin red quantitative value (0.246±0.006) were significantly higher than those of other groups (all <i>P</i><0.05), indicating that the SPO50 group exhibited the optimal <i>in vitro</i> osteogenic differentiation-promoting performance. RT-qPCR revealed that all SPO groups exhibited significantly hi
目的:研究碳纤维增强聚醚酮(CFR-PEEK)的最佳表面改性方案,以提高材料的生物活性和成骨性能。这是通过磺化和聚多巴胺(PDA)修饰构建多孔结构,随后将成骨生长肽(OGP)移植到表面来实现的。方法:以CFR-PEEK为对照组,CFR-PEEK标本依次进行6分钟磺化、水热处理(SPK组)、PDA修饰(SPD组),接枝25、50、100 μg/ml OGP (SPO25、SPO50、SPO100组)。采用扫描电镜(SEM)、衰减全反射傅立叶变换红外光谱(ATR-FTIR)、x射线光电子能谱(XPS)和接触角测试等方法分析各组试样的表面形貌、官能团、元素组成和亲水性。各组表面培养小鼠骨祖细胞(MC3T3-E1)。通过细胞增殖试验、免疫荧光染色、碱性磷酸酶(ALP)和茜素红染色、定量分析和实时荧光定量PCR (RT-qPCR)评估细胞粘附、增殖和成骨分化能力。结果:SEM显示,磺化处理后的试样表面形成了均匀的三维多孔结构。SPD组和SPO组的ATR-FTIR和XPS表现出明显的特征峰;与CFR-PEEK和SPK相比,所有SPO组的接触角测量结果显示亲水性明显优于SPK,其中SPO50组亲水性最佳(表面接触角:35.3°±2.5°),与其他组(所有PPPin体外成骨分化促进性能)相比具有统计学显著差异。RT-qPCR显示,与CFR-PEEK组相比,所有SPO组在成骨早期(7 d)的runt相关转录因子-2 (RUNX2)和Ⅰ型胶原的表达均显著高于CFR-PEEK组。诱导后14 d, SPO50组RUNX2和骨桥蛋白的表达量达到峰值(分别为3.325±0.225和2.550±0.107),显著高于其他各组(均为p)。结论:磺化PDA修饰可以在CFR-PEEK表面构建多孔结构,有效接枝OGP。SPO50组表现出最佳的细胞粘附、增殖和成骨分化能力。
{"title":"[<i>In vitro</i> study on the osteogenic potential of sulfonated and osteogenic growth peptide co-modified carbon fiber-reinforced polyetheretherketone].","authors":"Y X Lin, S Q Wang, Y Z Lai, J J Su","doi":"10.3760/cma.j.cn112144-20250923-00375","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250923-00375","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To determine an optimal surface modification protocol for carbon fiber-reinforced polyether ether ketone (CFR-PEEK), this study investigated the enhancement of material bioactivity and osteogenic properties. This was achieved by constructing a porous structure via sulfonation and polydopamine (PDA) modification and subsequently grafting osteogenic growth peptides (OGP) onto the surface. &lt;b&gt;Methods:&lt;/b&gt; Using CFR-PEEK as the control group, CFR-PEEK specimens were sequentially subjected to 6 minute of sulfonation, hydrothermal treatment (SPK group), and PDA modification (SPD group), followed by grafting with 25, 50, or 100 μg/ml OGP (SPO25, SPO50, SPO100 groups). Surface morphology, functional groups, elemental composition, and hydrophilicity of each test specimen group were analyzed using scanning electron microscopy (SEM), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), and contact angle testing. Mouse osteoprogenitor cells (MC3T3-E1) were cultured on the surfaces of each group. Cell adhesion, proliferation, and osteogenic differentiation capabilities were evaluated through cell proliferation assays, immunofluorescence staining, alkaline phosphatase (ALP) and alizarin red staining, quantitative analysis, and real-time fluorescence quantitative PCR (RT-qPCR). &lt;b&gt;Results:&lt;/b&gt; SEM revealed that the surface of the specimens formed a uniform three-dimensional porous structure after sulfonation treatment. ATR-FTIR and XPS revealed distinct characteristic peaks in the SPD and SPO groups; contact angle measurements demonstrated significantly superior hydrophilicity in all SPO groups compared to CFR-PEEK and SPK, with SPO50 group exhibiting optimal hydrophilicity (surface contact angle: 35.3°±2.5°), showing statistically significant differences from other groups (all &lt;i&gt;P&lt;/i&gt;&lt;0.05). Cell proliferation assays demonstrated no cytotoxicity in the SPK, SPD, and SPO groups, with all significantly promoting cell proliferation (compared to CFR-PEEK). Among these, the SPO50 group exhibited significantly higher cell proliferation (1.365±0.049) on day 5 than other groups (&lt;i&gt;P&lt;/i&gt;&lt;0.05), showing the best efficacy. SPK and SPD groups exhibited good cell spreading, while SPO groups (especially SPO50 and SPO100) demonstrated optimal cell adhesion properties. ALP staining and alizarin red staining results, along with their quantitative analysis, revealed that the SPO50 group exhibited the deepest ALP staining at both 7 and 14 d of osteogenic induction, and also demonstrated the deepest alizarin red staining at 14 days. Correspondingly, its 14-day ALP activity (0.057±0.001) and alizarin red quantitative value (0.246±0.006) were significantly higher than those of other groups (all &lt;i&gt;P&lt;/i&gt;&lt;0.05), indicating that the SPO50 group exhibited the optimal &lt;i&gt;in vitro&lt;/i&gt; osteogenic differentiation-promoting performance. RT-qPCR revealed that all SPO groups exhibited significantly hi","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"239-250"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pierre Fauchard's life and his contributions to the professionalization of dentistry]. [皮埃尔·福沙尔的一生及其对牙科专业化的贡献]。
Q4 Medicine Pub Date : 2026-02-09 DOI: 10.3760/cma.j.cn112144-20250914-00362
X Y Gu, Y F Zhu, J Zhou

Pierre Fauchard is frequently cited in textbooks and monographs on the history of dentistry and is widely recognized for his significant role in the development of early modern dental practice. However, existing studies tend to focus on his personal anecdotes or specific technical innovations, and have yet to address the fundamental question on why Fauchard has received such scholarly appraisal from the broader perspective of dental history. Drawing on Fauchard's biography, his seminal work The Surgeon Dentist, or Treatise on the Teeth, and interactions with the scholarly community of his time, this study systematically analyzes his key contributions to dental theory, clinical practice, and the formation of professional dental identity. This research helps fill a gap in Chinese-language scholarship and provides useful insights for the study of dental history and medical humanities education.

皮埃尔·福沙尔经常被引用在教科书和专著对牙科的历史,并被广泛认可,他在早期现代牙科实践的发展的重要作用。然而,现有的研究倾向于关注他的个人轶事或具体的技术创新,并且尚未解决为什么Fauchard从更广泛的牙科史角度获得如此学术评价的根本问题。借鉴Fauchard的传记,他的开创性作品《外科牙医》,或《牙齿专论》,以及与他那个时代的学术界的互动,本研究系统地分析了他对牙科理论、临床实践和专业牙科身份形成的关键贡献。本研究有助于填补中文学术研究的空白,并为口腔史研究和医学人文教育提供有益的见解。
{"title":"[Pierre Fauchard's life and his contributions to the professionalization of dentistry].","authors":"X Y Gu, Y F Zhu, J Zhou","doi":"10.3760/cma.j.cn112144-20250914-00362","DOIUrl":"https://doi.org/10.3760/cma.j.cn112144-20250914-00362","url":null,"abstract":"<p><p>Pierre Fauchard is frequently cited in textbooks and monographs on the history of dentistry and is widely recognized for his significant role in the development of early modern dental practice. However, existing studies tend to focus on his personal anecdotes or specific technical innovations, and have yet to address the fundamental question on why Fauchard has received such scholarly appraisal from the broader perspective of dental history. Drawing on Fauchard's biography, his seminal work <i>The Surgeon Dentist, or Treatise on the Teeth</i>, and interactions with the scholarly community of his time, this study systematically analyzes his key contributions to dental theory, clinical practice, and the formation of professional dental identity. This research helps fill a gap in Chinese-language scholarship and provides useful insights for the study of dental history and medical humanities education.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 2","pages":"186-191"},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
中华口腔医学杂志
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1