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Evaluation of mid-term results in our patients treated with N-Butyl cyanoacrylate embolization in saphenous vein insufficiency 应用氰基丙烯酸丁酯栓塞治疗隐静脉功能不全的中期疗效评价
Pub Date : 2023-01-01 DOI: 10.9739/tjvs.2023.05.015
A. Kocaoğlu, Cengiz Ovalı
Aim: The aim of this study is to present our mid-term results obtained from patients with advanced saphenous vein insufficiency treated with N-butyl cyanoacrylate embolization (CAE). Material and Methods: In the present study, we included 1013 patients who were treated with CAE because of moderate and severe saphenous vein insufficiency in Eskişehir Osmangazi University Medical Faculty Hospital Cardiovascular Surgery Clinic between January 2015 and November 2019. The patients were rechecked at 1st, 6th, 12th, 24th and 36th months. Venous Clinical Severity Score (VCSS) and Aberdeen Varicose Vein Questionnaire (AVVQ) results recorded at preoperative and postoperativee period. Doppler ultrasonography (USG) was performed to all patients in all controls. The absence of re-canalized flow in Doppler USG was accepted as the success of the procedure. Results: The mean age of 1013 patients was 51.27±14.30 years (448 men (44.2%) and 565 women (55.8%)). The average procedure time was 12.4±2.1 minutes, the average amount of CA used in the procedure was 1.6 ml (min: 1 ml - max: 2ml). In outpatient controls, complication rates was low, thrombophlebitis occurred in 17 patients (1.7%) and ecchymosis occurred in 9 patients (0.9%). The occlusion rate was 97.6% according to the 1-year follow-up results and 93.3% according to the 3-year follow-up results. The decrease in VCSS and AVVQ scores was statistically significant when the preoperative and postoperative period results compared (p<.05). Conclusion: In the present study, we think that CAE is a safely and effective treatment method for saphenous vein insufficiency. It has low complication, high occlusion rates and provides better comfort to the patients.
目的:本研究的目的是报告我们对晚期隐静脉功能不全患者采用氰基丙烯酸酯正丁酯栓塞(CAE)治疗的中期结果。材料与方法:在本研究中,我们纳入了2015年1月至2019年11月在eskikiehir Osmangazi大学医学院附属医院心血管外科诊所因中重度隐静脉功能不全而接受CAE治疗的1013例患者。于第1、6、12、24、36个月复查。术前、术后分别记录静脉临床严重程度评分(VCSS)和阿伯丁静脉曲张问卷(AVVQ)。所有患者均行多普勒超声检查(USG)。在多普勒USG中没有再通流被认为是手术的成功。结果:1013例患者平均年龄51.27±14.30岁,其中男性448例(44.2%),女性565例(55.8%)。平均手术时间为12.4±2.1分钟,平均CA用量为1.6 ml(最小为1 ml -最大为2ml)。在门诊对照组中,并发症发生率较低,17例(1.7%)患者发生血栓性静脉炎,9例(0.9%)患者发生瘀斑。1年随访时闭塞率为97.6%,3年随访时闭塞率为93.3%。术前、术后VCSS、AVVQ评分比较,差异有统计学意义(p< 0.05)。结论:CAE是一种安全有效的治疗隐静脉功能不全的方法。并发症少,闭塞率高,患者舒适度好。
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引用次数: 0
Detection of unexpected aortic aneurysms by using computed tomography in emergency department: A retrospective analysis of more than 10.000 patients 在急诊科使用计算机断层扫描检测意外主动脉瘤:超过10,000例患者的回顾性分析
Pub Date : 2023-01-01 DOI: 10.9739/tjvs.2023.03.09
Hülya Sevi̇l, F. Sevil, M. Tort, U. Aksu, Cigdem Ozer Gokaslan, S. Ozdinc, N. Becit
Aim: This study aims to determine the prevalence of aortic aneurysms (AA) on computed tomography (CT) in the emergency department. Material and Methods: A total of 10219 CT images were retrospectively analyzed (7610 thoracic, 6148 abdominal CT). A thoracic aortic diameter greater than 50 mm, an abdominal aortic diameter greater than 30 mm, or an aortic diameter greater than 50% of normal were considered AA. The baseline demographic and clinical characteristics of patients with thoracic AA (TAA) and abdominal AA (AAA) were compared to those without AA. Results: TAA was found in 990 (13%) of 7610 patients who had thoracic CT, while AAA was found in 66 (1.07%) of 6148 patients who had abdominal CT. In aneurysm groups, advanced age (p<0.001), male gender (p<0.001), aortic calcification (p<0.001), hyperlipidemia (p<0.001), coronary artery disease (p<0.001), hypertension (p<0.001), and diabetes mellitus (p<0.001) were more common and significantly different. Smoking was observed more frequently in the group with aneurysms (p<0.001). Among the groups, hospital mortality was higher in the aneurysm group (p<0.001). Surgery was recommended in 30 (3%) of TAA patients whose aortic diameter was greater than 55 mm; however, surgery could be performed in 20 (2%) of these patients. Surgery was recommended for 16 (24%) of AAA patients, but surgery could be performed only in 12 of them (18%). Conclusion: Attention to aortic pathologies, particularly AA, in patients undergoing radiological imaging in the emergency department for various reasons allows for the early detection of asymptomatic but potentially fatal aneurysms.
目的:本研究旨在确定急诊科主动脉瘤(AA)的计算机断层扫描(CT)患病率。材料与方法:回顾性分析10219张CT图像(胸部7610张,腹部6148张)。胸主动脉直径大于50mm,腹主动脉直径大于30mm,或主动脉直径大于正常值的50%为AA。将胸椎AA (TAA)和腹部AA (AAA)患者的基线人口学和临床特征与无AA的患者进行比较。结果:7610例胸部CT检查中发现TAA 990例(13%),6148例腹部CT检查中发现AAA 66例(1.07%)。在动脉瘤组中,高龄(p<0.001)、男性(p<0.001)、主动脉钙化(p<0.001)、高脂血症(p<0.001)、冠状动脉疾病(p<0.001)、高血压(p<0.001)、糖尿病(p<0.001)更为常见,且差异有统计学意义。动脉瘤组吸烟更频繁(p<0.001)。两组间,动脉瘤组住院死亡率较高(p<0.001)。主动脉直径大于55mm的TAA患者中有30例(3%)推荐手术治疗;然而,这些患者中有20例(2%)可以进行手术。16例(24%)AAA患者推荐手术,但只有12例(18%)可以手术。结论:在急诊科因各种原因接受放射成像的患者中,注意主动脉病变,特别是AA,可以早期发现无症状但可能致命的动脉瘤。
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引用次数: 0
Patient awareness, disease-specific knowledge, and patient adherence to endovascular treated elective infrarenal abdominal aortic aneurysm 患者意识、疾病特异性知识和患者对血管内治疗选择性肾下腹主动脉瘤的依从性
Pub Date : 2023-01-01 DOI: 10.9739/tjvs.2023.06.016
G. Deniz, S. Mola, H. Iscan, Muhammet Selim Yasar, Alp Yildirim, Naim Boran Tumer, Anıl Özen
Aim: Patient awareness and disease-specific knowledge are essential for shared decision-making of patients with abdominal aortic aneurysms. With this pilot survey, we aimed to figure out the obstacles to patient's awareness about the aortic aneurysm before and after the procedure. Material and Methods: Patients who experienced elective endovascular aortic aneurysm repair (EVAR) in our Cardiovascular Surgery Clinic between 2019 to 2023 were the selected patient cohort. The first 50 patients who visited our outpatient clinic were given a questionnaire about their awareness of the aneurysm disease, disease-specific knowledge, and the comprehensibility of the patient information provided before and after the procedure. Results: The mean age of our patients was 66±6.9. Younger patients were more aware of the situation before the information (p=0.013). Patients anxious about the disease were also more conscious about the aortic aneurysm (p=0.02). Although all patients were given preoperative information and disease-specific information by the same team, 13 patients (26%) could not recall anything about the disease and did not recall what operation was performed and why. Thirty-seven patients (74%) gained awareness about the disease. The patients with at least an educational level above high school gained more awareness than others (p=0.04). Conclusion: The Classical informatory model seems insufficient for gaining awareness and consciousness for older patients and with patients with low level of education. Strengthened patient-practitioner interaction with supplemental technologies (leaflets, interactive media, audio tapes, etc.) may improve these patients' shared decision-making. More prospective research is required in this regard.
目的:患者意识和疾病特异性知识对腹主动脉瘤患者的共同决策至关重要。通过这个试点调查,我们的目的是找出患者在手术前后对动脉瘤的认识的障碍。材料和方法:入选的患者队列为2019 - 2023年在我院心血管外科诊所行选择性血管内动脉瘤修复术(EVAR)的患者。前50名到我们门诊就诊的患者填写了一份问卷,内容涉及他们对动脉瘤疾病的认识、疾病特异性知识以及对手术前后提供的患者信息的可理解性。结果:患者平均年龄66±6.9岁。年龄较小的患者在信息发布前对病情的了解程度较高(p=0.013)。焦虑的患者对动脉瘤的意识也更强(p=0.02)。虽然所有患者的术前信息和疾病特异性信息均由同一团队提供,但13名患者(26%)不记得任何有关疾病的信息,也不记得进行了什么手术以及为什么进行手术。37名患者(74%)对该疾病有所了解。高中及以上文化程度患者的认知程度高于其他患者(p=0.04)。结论:经典的信息模型对于老年患者和低文化程度患者的认知和意识似乎不足。通过补充技术(传单、互动媒体、录音带等)加强患者与医生的互动,可能会改善这些患者的共同决策。在这方面需要更多的前瞻性研究。
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引用次数: 0
Could direct-acting oral anticoagulant be a possible cause of delayed pseudoaneurysm? A case report 直接作用的口服抗凝剂可能是迟发性假性动脉瘤的原因吗?病例报告
Pub Date : 2023-01-01 DOI: 10.9739/tjvs.2023.03.07
N. Katrancioglu, F. Serhatlioglu
Delayed iatrogenic pseudoaneurysm (IPA) is very rare. We aimed to present a case of delayed femoral IPA using apixaban, which developed four months after coronary intervention (PCI). A 75-year-old female patient who had PCI four months ago presented with right femoral artery IPA that started one month ago, with no recent history of trauma, infection, or new procedures, except for diabetes and apixaban use. The occurrence of IPA at the insertion site four months after the initial procedure is an infrequent complication. Delayed IPA risk factors are trauma, infection, anticoagulant use, and inflammatory disease. Since no other risk factor was found in our case, the cause of IPA seems to be apixaban. Our case highlights the importance of considering delayed IPA as a potential complication, which may manifest up to four months after the initial procedure, especially in diabetic patients who are on anticoagulant therapy.
迟发性医源性假性动脉瘤(IPA)非常罕见。我们的目的是报告一例在冠状动脉介入治疗(PCI) 4个月后使用阿哌沙班发生的延迟性股骨IPA。1例75岁女性患者4个月前行PCI, 1个月前出现右股动脉IPA,近期无外伤、感染史,除糖尿病和阿哌沙班使用外,无新手术史。在初始手术后4个月在植入部位发生异位成形物是一种罕见的并发症。迟发性IPA的危险因素包括创伤、感染、抗凝剂使用和炎症性疾病。由于在本病例中未发现其他危险因素,IPA的病因似乎是阿哌沙班。我们的病例强调了考虑延迟IPA作为潜在并发症的重要性,延迟IPA可能在初始手术后4个月出现,特别是在接受抗凝治疗的糖尿病患者中。
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引用次数: 0
Antegrade and retrograde access in the endovascular treatment of femoropopliteal chronic total occlusions 股腘动脉慢性全闭塞血管内治疗的顺、逆行通路
Pub Date : 2023-01-01 DOI: 10.9739/tjvs.2023.04.010
M. Donbaloğlu, S. Gürkan, O. Gur
Aim: In this study, the aim was to investigate whether antegrade or retrograde approaches are superior in the endovascular treatment of femoropopliteal chronic total occlusions (CTO). Material and Methods: A total of 437 patients who were diagnosed with CTO in the femoropopliteal region and who subsequently underwent endovascular procedures between February 2019 and April 2022 were evaluated retrospectively. The patients were grouped as antegrade access and retrograde access. All patients were classified according to the Rutherford and TASC (Transatlantic Intersociety Consensus II) classification. The patients were followed for 2 years. Above-ankle amputation and >50% stenosis in the target vessel were considered a failure. ABI, improvement in clinical symptoms, and limb salvage were evaluated in controls. Results: Antegrade approach was performed in 218 of the endovascular procedures. Antegrade recanalization was successful in 201 patients (92.2%), and failed antegrade attempt was seen in 17 because the lesion could not be crossed. Retrograde approach was used in 197 of endovascular interventions. Successful retrograde recanalization was unsuccessful in 185 patients (93.9%), and retrograde intervention was unsuccessful in 12 patients because the lesion could not be crossed. When the two-year restenosis numbers were examined, it was 61 (30.3%) in the antegrade group, while it was 49 (25.5%) in the retrograde group, and there was a significant difference between the groups. When the one-year stent occlusions between the groups were examined, it was 14 (6.9%) in the antegrade group and 8 (4.1%) in the retrograde group, and there was a statistically significant difference between the groups. Conclusion: The retrograde approach is as effective and safe as the antegrade approach in the treatment of femoropopliteal CTO. It should be noted that it can be used as an alternative method without the need for any support device, especially in cases where the antegrade approach is unsuccessful.
目的:在本研究中,目的是探讨顺行或逆行入路在股腘动脉慢性全闭塞(CTO)的血管内治疗中是否优越。材料和方法:对2019年2月至2022年4月期间诊断为股腘区CTO并随后接受血管内手术的437例患者进行回顾性评估。患者分为顺行通路和逆行通路。所有患者均按照卢瑟福和TASC(跨大西洋社会共识II)分类进行分类。随访2年。踝关节以上截肢和靶血管狭窄>50%被认为是失败。对照组评估ABI、临床症状改善和肢体保留情况。结果:218例血管内手术采用顺行入路。201例(92.2%)患者行顺行再通成功,17例因病变不能穿过而行顺行再通失败。197例血管内介入手术采用逆行入路。185例(93.9%)患者逆行再通不成功,12例患者因病变不能交叉而逆行干预不成功。观察2年再狭窄数,顺行组为61例(30.3%),逆行组为49例(25.5%),两组间差异有统计学意义。两组间一年支架闭塞情况比较,顺行组为14例(6.9%),逆行组为8例(4.1%),两组间差异有统计学意义。结论:逆行入路与顺行入路治疗股腘动脉CTO一样安全有效。应该注意的是,它可以作为一种替代方法,而不需要任何支撑装置,特别是在顺行方法不成功的情况下。
{"title":"Antegrade and retrograde access in the endovascular treatment of femoropopliteal chronic total occlusions","authors":"M. Donbaloğlu, S. Gürkan, O. Gur","doi":"10.9739/tjvs.2023.04.010","DOIUrl":"https://doi.org/10.9739/tjvs.2023.04.010","url":null,"abstract":"Aim: In this study, the aim was to investigate whether antegrade or retrograde approaches are superior in the endovascular treatment of femoropopliteal chronic total occlusions (CTO). Material and Methods: A total of 437 patients who were diagnosed with CTO in the femoropopliteal region and who subsequently underwent endovascular procedures between February 2019 and April 2022 were evaluated retrospectively. The patients were grouped as antegrade access and retrograde access. All patients were classified according to the Rutherford and TASC (Transatlantic Intersociety Consensus II) classification. The patients were followed for 2 years. Above-ankle amputation and >50% stenosis in the target vessel were considered a failure. ABI, improvement in clinical symptoms, and limb salvage were evaluated in controls. Results: Antegrade approach was performed in 218 of the endovascular procedures. Antegrade recanalization was successful in 201 patients (92.2%), and failed antegrade attempt was seen in 17 because the lesion could not be crossed. Retrograde approach was used in 197 of endovascular interventions. Successful retrograde recanalization was unsuccessful in 185 patients (93.9%), and retrograde intervention was unsuccessful in 12 patients because the lesion could not be crossed. When the two-year restenosis numbers were examined, it was 61 (30.3%) in the antegrade group, while it was 49 (25.5%) in the retrograde group, and there was a significant difference between the groups. When the one-year stent occlusions between the groups were examined, it was 14 (6.9%) in the antegrade group and 8 (4.1%) in the retrograde group, and there was a statistically significant difference between the groups. Conclusion: The retrograde approach is as effective and safe as the antegrade approach in the treatment of femoropopliteal CTO. It should be noted that it can be used as an alternative method without the need for any support device, especially in cases where the antegrade approach is unsuccessful.","PeriodicalId":23982,"journal":{"name":"Turkish Journal of Vascular Surgery","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80022862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective effects of curcumin on kidney tissue in ischemia-reperfusion injury in rats 姜黄素对大鼠肾缺血再灌注损伤的保护作用
Pub Date : 2023-01-01 DOI: 10.9739/tjvs.2023.03.08
F. Sevil, Hülya Sevi̇l, N. Becit, M. Tort, U. Aksu, Z. Saritas, H. Demirel, A. Bulbul
Aim: Kidney damage caused by ischemia-reperfusion (IR) is a serious clinical problem. Many studies have emphasized the antioxidant and anti-inflammatory properties of Curcumin. Material and Methods: Wistar-Albino male rats were divided into three groups. The sham group was the group in which only laparotomy was performed, the IR group was the group in which the infrarenal aorta was clamped after laparotomy and ischemia-reperfusion was created, and the IR+ curcumin group was the group in which intraperitoneal curcumin was given 1 hour before the procedure and the same procedures were repeated with the IR group. After creating the IR, blood and kidney tissue were taken from the rats and biochemical and histopathological examinations were performed. Results: Potassium (p=0.005), urea (p=0.050), and blood urea nitrogen (p=0.050) levels were higher in the IR+curcumin group. While total antioxidant status was found to be high in the IR+curcumin group (p=0.021), there was no difference in total oxidant status across the groups (p=0.069). Interleukin (IL)-1β and IL-6 were found to be higher in the IR group (p=0.014, p=0.022, respectively). Tumour necrosis factor-α was higher in the IR group than in other groups (p=0.020). Interferon-γ did not differ across groups (p=0.140). In the histopathological examination, the IR group had more damage to the glomerulus and tubular epithelial cells than the other groups (p<0.001). Conclusion: Curcumin, despite its anti-inflammatory and antioxidant characteristics, had no protective effect on renal functions in IR-induced kidney injury. It was found that it suppresses the inflammatory response and is effective in preserving renal tissue structure.
目的:肾缺血再灌注损伤是一个严重的临床问题。许多研究都强调姜黄素的抗氧化和抗炎特性。材料与方法:Wistar-Albino雄性大鼠分为3组。假手术组为仅开腹手术组,IR组为开腹后夹持肾下主动脉形成缺血再灌注组,IR+姜黄素组为术前1小时腹腔注射姜黄素组,与IR组重复相同的步骤。制备IR后,取大鼠血液和肾脏组织,进行生化和组织病理学检查。结果:IR+姜黄素组血钾(p=0.005)、尿素(p=0.050)、尿素氮(p=0.050)水平升高。虽然发现IR+姜黄素组的总抗氧化状态较高(p=0.021),但两组之间的总氧化状态没有差异(p=0.069)。IR组白细胞介素(IL)-1β和IL-6升高(p=0.014, p=0.022)。IR组肿瘤坏死因子-α高于其他各组(p=0.020)。干扰素γ在各组间无差异(p=0.140)。在组织病理学检查中,IR组对肾小球和小管上皮细胞的损伤明显高于其他组(p<0.001)。结论:姜黄素虽具有抗炎、抗氧化作用,但对ir所致肾损伤的肾功能无保护作用。发现它能抑制炎症反应,有效地保存肾组织结构。
{"title":"Protective effects of curcumin on kidney tissue in ischemia-reperfusion injury in rats","authors":"F. Sevil, Hülya Sevi̇l, N. Becit, M. Tort, U. Aksu, Z. Saritas, H. Demirel, A. Bulbul","doi":"10.9739/tjvs.2023.03.08","DOIUrl":"https://doi.org/10.9739/tjvs.2023.03.08","url":null,"abstract":"Aim: Kidney damage caused by ischemia-reperfusion (IR) is a serious clinical problem. Many studies have emphasized the antioxidant and anti-inflammatory properties of Curcumin. Material and Methods: Wistar-Albino male rats were divided into three groups. The sham group was the group in which only laparotomy was performed, the IR group was the group in which the infrarenal aorta was clamped after laparotomy and ischemia-reperfusion was created, and the IR+ curcumin group was the group in which intraperitoneal curcumin was given 1 hour before the procedure and the same procedures were repeated with the IR group. After creating the IR, blood and kidney tissue were taken from the rats and biochemical and histopathological examinations were performed. Results: Potassium (p=0.005), urea (p=0.050), and blood urea nitrogen (p=0.050) levels were higher in the IR+curcumin group. While total antioxidant status was found to be high in the IR+curcumin group (p=0.021), there was no difference in total oxidant status across the groups (p=0.069). Interleukin (IL)-1β and IL-6 were found to be higher in the IR group (p=0.014, p=0.022, respectively). Tumour necrosis factor-α was higher in the IR group than in other groups (p=0.020). Interferon-γ did not differ across groups (p=0.140). In the histopathological examination, the IR group had more damage to the glomerulus and tubular epithelial cells than the other groups (p<0.001). Conclusion: Curcumin, despite its anti-inflammatory and antioxidant characteristics, had no protective effect on renal functions in IR-induced kidney injury. It was found that it suppresses the inflammatory response and is effective in preserving renal tissue structure.","PeriodicalId":23982,"journal":{"name":"Turkish Journal of Vascular Surgery","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88519642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative objective and subjective voice analysis in patients who underwent carotid endarterectomy and carotid body tumor resection 颈动脉内膜切除术及颈动脉体肿瘤切除术患者术后主客观声音分析
Pub Date : 2023-01-01 DOI: 10.9739/tjvs.2023.04.014
Umit Kahraman, O. Balcioglu, S. Ertugay, E. Oguz, H. Posacioglu
Aim: This study aimed to compare voice changes after Carotid endarterectomy (CEA) and Glomus body tumor resection with objective instrumental and acoustic assessments. Material and Methods: A total of 14 patients underwent CEA or glomus carotid tumor resection at our institution between 2009 and 2013. Among the 14 patients, two patients were excluded due to vocal cord paralysis. This study was applied to 12 patients. Patients were called retrospectively, and objective and subjective voice parameters were measured and compared. Voice handicap index was used to measure subjective voice parameters. Objective voice analysis was performed for patients by using Multi-dimensional voice programming (MDVP), a computer-aided program. Results: A total of 12 patients were included in the study. Five patients underwent carotid endarterectomy. Glomus tumor resection was performed on seven patients. Of the patients who underwent carotid endarterectomy, four were male and one was female. Three of the patients who underwent glomus tumor resection were male and four were female. Voice handicap index (VHI) showed that two patients who underwent glomus tumor resection experienced moderate problems and the patients who underwent CEA had no obvious problems. Patients who underwent glomus carotid tumor resection obtained higher values in all MDVP parameters than those who underwent CEA. Conclusion: Despite the small number of patients, it can be said that glomus tumor resection in neck surgery, that is, tumor surgery, causes more voice changes than carotid endarterectomy operations. The elevated objective sound parameters found in this study necessitate that patients should be informed regarding the potential of developing postoperative dysphonia, especially those who rely on their voice as their profession (e.g. sound artists, teachers, politicians).
目的:本研究旨在比较颈动脉内膜切除术(CEA)和Glomus体肿瘤切除术后的声音变化,并进行客观的仪器和声学评估。材料和方法:2009年至2013年,共有14例患者在我院接受了CEA或颈动脉球瘤切除术。14例患者中2例因声带麻痹被排除。本研究应用于12例患者。回顾性地对患者进行呼叫,并测量和比较客观和主观声音参数。语音障碍指数用于测量主观语音参数。采用计算机辅助程序多维语音编程(Multi-dimensional voice programming, MDVP)对患者进行客观语音分析。结果:共纳入12例患者。5例患者行颈动脉内膜切除术。对7例患者行血管球瘤切除术。在接受颈动脉内膜切除术的患者中,4名男性,1名女性。行血管球瘤切除术的患者中男性3例,女性4例。嗓音障碍指数(VHI)显示2例行球囊瘤切除术的患者出现中度问题,而行CEA的患者无明显问题。行颈动脉血管瘤切除术的患者在所有MDVP参数上均高于行CEA的患者。结论:尽管患者数量较少,但可以说颈部手术中血管球瘤切除术(即肿瘤手术)比颈动脉内膜切除术引起的声音改变更多。本研究中发现的客观声音参数升高,需要告知患者术后发生发声障碍的可能性,特别是那些以声音为职业的患者(如声音艺术家、教师、政治家)。
{"title":"Postoperative objective and subjective voice analysis in patients who underwent carotid endarterectomy and carotid body tumor resection","authors":"Umit Kahraman, O. Balcioglu, S. Ertugay, E. Oguz, H. Posacioglu","doi":"10.9739/tjvs.2023.04.014","DOIUrl":"https://doi.org/10.9739/tjvs.2023.04.014","url":null,"abstract":"Aim: This study aimed to compare voice changes after Carotid endarterectomy (CEA) and Glomus body tumor resection with objective instrumental and acoustic assessments. Material and Methods: A total of 14 patients underwent CEA or glomus carotid tumor resection at our institution between 2009 and 2013. Among the 14 patients, two patients were excluded due to vocal cord paralysis. This study was applied to 12 patients. Patients were called retrospectively, and objective and subjective voice parameters were measured and compared. Voice handicap index was used to measure subjective voice parameters. Objective voice analysis was performed for patients by using Multi-dimensional voice programming (MDVP), a computer-aided program. Results: A total of 12 patients were included in the study. Five patients underwent carotid endarterectomy. Glomus tumor resection was performed on seven patients. Of the patients who underwent carotid endarterectomy, four were male and one was female. Three of the patients who underwent glomus tumor resection were male and four were female. Voice handicap index (VHI) showed that two patients who underwent glomus tumor resection experienced moderate problems and the patients who underwent CEA had no obvious problems. Patients who underwent glomus carotid tumor resection obtained higher values in all MDVP parameters than those who underwent CEA. Conclusion: Despite the small number of patients, it can be said that glomus tumor resection in neck surgery, that is, tumor surgery, causes more voice changes than carotid endarterectomy operations. The elevated objective sound parameters found in this study necessitate that patients should be informed regarding the potential of developing postoperative dysphonia, especially those who rely on their voice as their profession (e.g. sound artists, teachers, politicians).","PeriodicalId":23982,"journal":{"name":"Turkish Journal of Vascular Surgery","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91481523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extremely rare case; Venous aneurysm 极罕见病例;静脉瘤
Pub Date : 2022-11-15 DOI: 10.9739/tjvs.2022.09.06
D. S. Beyazpinar, Deniz Şerefli, A. Harman, H. T. Akay
Venous aneurysm is very rare espacially inferior vena cava (IVC) aneurysm is extremely rare. Etiology is not clear and risk factors can be inflammatory disease, thrombosis, trauma and long term complication of long term right heart failure. Angiography with computer tomography (CTA), magnetic resonance angiography (MRA) and convantionel venography can use for diagnose. 30 years old male patient admistered to clinic for lower abdominal pain for a month. Largest diameter in subhepatic region and left renal vein were 67mm and 26mm respectively. Literature there were limited numbers of case described. Because of this reason there was no quide or no adopted treatment aprroach was defined. Hardest and challenging part is giving the decision of treatment.
静脉动脉瘤是非常罕见的,尤其是下腔静脉(IVC)动脉瘤是极其罕见的。病因尚不清楚,危险因素可能是炎症性疾病、血栓形成、创伤和长期右心衰的长期并发症。血管造影与计算机断层扫描(CTA),磁共振血管造影(MRA)和常规血管造影可用于诊断。患者男性,30岁,因下腹部疼痛就诊1个月。肝下区和左肾静脉最大直径分别为67mm和26mm。文献中对病例的描述数量有限。由于这个原因,没有指南或没有确定采用的治疗方法。最困难和最具挑战性的部分是做出治疗的决定。
{"title":"Extremely rare case; Venous aneurysm","authors":"D. S. Beyazpinar, Deniz Şerefli, A. Harman, H. T. Akay","doi":"10.9739/tjvs.2022.09.06","DOIUrl":"https://doi.org/10.9739/tjvs.2022.09.06","url":null,"abstract":"Venous aneurysm is very rare espacially inferior vena cava (IVC) aneurysm is extremely rare. Etiology is not clear and risk factors can be inflammatory disease, thrombosis, trauma and long term complication of long term right heart failure. Angiography with computer tomography (CTA), magnetic resonance angiography (MRA) and convantionel venography can use for diagnose. 30 years old male patient admistered to clinic for lower abdominal pain for a month. Largest diameter in subhepatic region and left renal vein were 67mm and 26mm respectively. Literature there were limited numbers of case described. Because of this reason there was no quide or no adopted treatment aprroach was defined. Hardest and challenging part is giving the decision of treatment.","PeriodicalId":23982,"journal":{"name":"Turkish Journal of Vascular Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74477988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects Of Rivaroxaban And Apixaban On Intimal Hyperplasia In Rabbits 利伐沙班和阿哌沙班对家兔内膜增生的影响
Pub Date : 2022-11-15 DOI: 10.9739/tjvs.2022.09.03
Mustafa Barış Kemahlı, T. Gençpınar, H. Dursun, Ç. Bilen, P. Akokay, S. Bayrak, A. Erdal
Aim: Intimal hyperplasia causes vascular occlusion and its optimal treatment is unknown. In this study, we evaluated the effectiveness of Apixaban and Rivaroxaban treatment for preventing intimal hyperplasia in rabbits. Material and Methods: The rabbits (n = 15) were randomly divided into three groups. Reanastomoses are applied to the carotid artery. All groups received 100 U/kg heparin sodium during the operation period. Group A (n = 5) as a control group had no medication. Group B (n = 5) was given Rivaroxaban 3 mg/kg/day. In-group C (n = 5) Apixaban was administered per orally 10 mg/kg. At the end of the treatment on the 28th day, carotid artery specimens were excised and evaluated histologically. Results: Increased intima thickness was observed in the control group than the drug groups (P=0.019, P=0.007). It was found that there was no difference between groups in terms of lumen diameter, lumen area, tunica media area and tunica media thickness. There was difference between groups in terms of caspase 3 or TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) staining (p<0.05). Conclusion: Apixaban and Rivaroxaban may have protective efficacy against intimal hyperplasia after vascular surgical intervention.
目的:内膜增生引起血管闭塞,其最佳治疗方法尚不清楚。在这项研究中,我们评估了阿哌沙班和利伐沙班治疗预防家兔内膜增生的有效性。材料与方法:将15只家兔随机分为3组。颈动脉吻合术应用于颈动脉。所有组在手术期间均给予100 U/kg肝素钠。A组(n = 5)为对照组,不给药。B组(n = 5)给予利伐沙班3 mg/kg/d。C组(n = 5)给予阿哌沙班,每次口服10 mg/kg。治疗结束第28天,切除颈动脉标本进行组织学评价。结果:对照组内膜厚度明显高于给药组(P=0.019, P=0.007)。各组间在管腔直径、管腔面积、中膜面积和中膜厚度方面均无差异。caspase 3和TUNEL(末端脱氧核苷酸转移酶dUTP缺口末端标记)染色组间差异有统计学意义(p<0.05)。结论:阿哌沙班和利伐沙班可能对血管手术后内膜增生有保护作用。
{"title":"Effects Of Rivaroxaban And Apixaban On Intimal Hyperplasia In Rabbits","authors":"Mustafa Barış Kemahlı, T. Gençpınar, H. Dursun, Ç. Bilen, P. Akokay, S. Bayrak, A. Erdal","doi":"10.9739/tjvs.2022.09.03","DOIUrl":"https://doi.org/10.9739/tjvs.2022.09.03","url":null,"abstract":"Aim: Intimal hyperplasia causes vascular occlusion and its optimal treatment is unknown. In this study, we evaluated the effectiveness of Apixaban and Rivaroxaban treatment for preventing intimal hyperplasia in rabbits. Material and Methods: The rabbits (n = 15) were randomly divided into three groups. Reanastomoses are applied to the carotid artery. All groups received 100 U/kg heparin sodium during the operation period. Group A (n = 5) as a control group had no medication. Group B (n = 5) was given Rivaroxaban 3 mg/kg/day. In-group C (n = 5) Apixaban was administered per orally 10 mg/kg. At the end of the treatment on the 28th day, carotid artery specimens were excised and evaluated histologically. Results: Increased intima thickness was observed in the control group than the drug groups (P=0.019, P=0.007). It was found that there was no difference between groups in terms of lumen diameter, lumen area, tunica media area and tunica media thickness. There was difference between groups in terms of caspase 3 or TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) staining (p<0.05). Conclusion: Apixaban and Rivaroxaban may have protective efficacy against intimal hyperplasia after vascular surgical intervention.","PeriodicalId":23982,"journal":{"name":"Turkish Journal of Vascular Surgery","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88150552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Thoracoabdominal aortic aneurysm repair: A Single center experience 胸腹主动脉瘤修复:单中心经验
Pub Date : 2022-11-15 DOI: 10.9739/tjvs.2022.09.08
U. Aydin, Z. Duman, Emre Yasar, Muhammed Bayram, Sefa Eltutan, Ersin Kadiroğulları, Onur Şen
Aim: The gold standard repair of thoracoabdominal aortic aneurysm (TAAA) is still open surgery. However, few cardiovascular centers are experienced in TAAA repair. The aim of this study was to examine the methods and four-year outcomes of the open TAAA repair program initiated by a single surgical team. Material and Methods: In this retrospective cohort, patients who were operated for TAAA between August 2018 and March 2022 were collected. Patients treated with the endovascular approach were excluded. After exclusion, 19 patients were included in our analysis. As postoperative outcomes, in-hospital mortality, spinal cord deficit, major neurologic complications, need for dialysis, and visceral ischemia were collected. Results: Crawford extent II TAAA repair was performed in 10 (52.6%) patients, Crawford extent III in 5 (26.3%) patients, and Crawford extent IV in 4 (21.1%) patients. In hospital mortality occurred in 6 (31.6%) patients. The causes of mortality were perioperative myocardial infarction in 2 (10.5%) patients, visceral ischemia in 1 (5.3%) patient, multisystem organ failure in 3 (15.8%) patients. The highest mortality rate (50.0%) occurred in Crawford extent II repair. Spinal cord deficit developed in 2 (10.5%) patients. Conclusion: Thoracoabdominal aortic aneurysm surgery is associated with high mortality rates. Open thoracoabdominal aortic aneurysm repair programs in tertiary vascular centers should be supported, to improve the surgical results of thoracoabdominal aortic aneurysm repair.
目的:胸腹主动脉瘤(TAAA)的金标准修复仍是开放性手术。然而,很少有心血管中心在TAAA修复方面有经验。本研究的目的是研究由一个外科团队发起的开放式TAAA修复计划的方法和四年的结果。材料与方法:在本回顾性队列中,收集了2018年8月至2022年3月期间因TAAA手术的患者。排除采用血管内入路治疗的患者。排除后,19例患者纳入我们的分析。术后结果包括住院死亡率、脊髓缺损、主要神经系统并发症、透析需求和内脏缺血。结果:10例(52.6%)患者行Crawford II级TAAA修复,5例(26.3%)患者行Crawford III级TAAA修复,4例(21.1%)患者行Crawford IV级TAAA修复。住院死亡6例(31.6%)。死亡原因为围手术期心肌梗死2例(10.5%),内脏缺血1例(5.3%),多系统脏器功能衰竭3例(15.8%)。致死率最高的是克劳福德区修复,为50.0%。2例(10.5%)患者出现脊髓缺损。结论:胸腹主动脉瘤手术死亡率高。应支持三级血管中心的开放性胸腹主动脉瘤修复方案,以提高胸腹主动脉瘤修复的手术效果。
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Turkish Journal of Vascular Surgery
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