Pub Date : 2015-09-03DOI: 10.4172/2165-7904.S1.013
Y. Ozturk
{"title":"Obesity, diabetes and metabolic syndrome in terms of preventive medicine and healthcare","authors":"Y. Ozturk","doi":"10.4172/2165-7904.S1.013","DOIUrl":"https://doi.org/10.4172/2165-7904.S1.013","url":null,"abstract":"","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129947218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-31DOI: 10.4172/2165-7904.1000270
Shan Liu, M. Fu, Sophia H. Hu, Vincent Y. Wang, R. Crupi, Jeanna M. Qiu, C. Cleland, G. Melkus
Background: Chinese Americans have increased rates for obesity in the United States. Little is known about obesity indicators and chronic illness, and the relationship between them in Chinese Americans. Methods: A descriptive and cross-sectional study was designed. Chinese-American adults were recruited from a community health center in New York. Obesity indicators including waist circumference (WC), hip circumference (HC), Body Mass Index (BMI), weight to hip ratio, weight to height ratio, fasting blood glucose (FPG), Glycated hemoglobin (HbA1C) were evaluated. Chronic illnesses were assessed using a researcher developed self-report checklist and verified by medical record review. Results: Among 162 Chinese American participants, who were recruited, 94 subjects had fewer than three chronic illnesses and 68 subjects had three or more chronic illnesses. The three most common chronic illnesses in this population were diabetes (65.4%), hypertension (46.9%), and eye problem (38.3%). Controlling for all demographic factors, numbers of chronic illnesses remained significant associations with obesity indicators of WC (p=0.006), HC (p=0.020), weight to height ratio (p=0.011), HbA1C (p=0.026). Obesity indicators also had significant associations with individual chronic illness of diabetes, hypertension, heart diseases, eye and food problems. Conclusion: General Obesity indicator (BMI), central obesity indicators (WC, HC, weight to height ratio) and HbA1c were significantly associated with chronic illnesses in Chinese Americans.
{"title":"Obesity Indicators and Chronic Illness among Chinese Americans: A Pilot Study","authors":"Shan Liu, M. Fu, Sophia H. Hu, Vincent Y. Wang, R. Crupi, Jeanna M. Qiu, C. Cleland, G. Melkus","doi":"10.4172/2165-7904.1000270","DOIUrl":"https://doi.org/10.4172/2165-7904.1000270","url":null,"abstract":"Background: Chinese Americans have increased rates for obesity in the United States. Little is known about obesity indicators and chronic illness, and the relationship between them in Chinese Americans. \u0000Methods: A descriptive and cross-sectional study was designed. Chinese-American adults were recruited from a community health center in New York. Obesity indicators including waist circumference (WC), hip circumference (HC), Body Mass Index (BMI), weight to hip ratio, weight to height ratio, fasting blood glucose (FPG), Glycated hemoglobin (HbA1C) were evaluated. Chronic illnesses were assessed using a researcher developed self-report checklist and verified by medical record review. \u0000Results: Among 162 Chinese American participants, who were recruited, 94 subjects had fewer than three chronic illnesses and 68 subjects had three or more chronic illnesses. The three most common chronic illnesses in this population were diabetes (65.4%), hypertension (46.9%), and eye problem (38.3%). Controlling for all demographic factors, numbers of chronic illnesses remained significant associations with obesity indicators of WC (p=0.006), HC (p=0.020), weight to height ratio (p=0.011), HbA1C (p=0.026). Obesity indicators also had significant associations with individual chronic illness of diabetes, hypertension, heart diseases, eye and food problems. \u0000Conclusion: General Obesity indicator (BMI), central obesity indicators (WC, HC, weight to height ratio) and HbA1c were significantly associated with chronic illnesses in Chinese Americans.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114398373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-31DOI: 10.4172/2165-7904.1000269
R. Lanyon, B. Maxwell
Purpose: Previous research has shown that pre-operative health status can serve as a moderator in enhancing the accuracy of certain variables for predicting sustained weight loss after gastric bypass surgery. The present study investigated the role of pre-operative stress level as a moderator in identifying useful pre-operative predictors of sustained weight loss. Materials and Methods: Follow-up data at a mean of 3.2 years post-operatively were available for 111 patients who had undergone pre-operative assessment on 227 variables including four psychological assessment instruments. These measures were studied for their success in predicting sustained weight loss separately for patients who were under low and high pre-operative stress. Results: As anticipated, several types of variables (support, coping skills, good adjustment, and good cognitive functioning) predicted success for both groups. In addition, for low-stress patients, social drinking and self-efficacy variables (strong expectations of a broad range of positive changes), and a broader range of personal support variables were the best predictors. For high-stress patients, the best predictors included the presence of a troubled intimate relationship, lack of attention to personal health matters, an active history of smoking, and the possible need for psychiatric medication. Overall, the results show some consistency with the basic postulates of selfdetermination theory. Conclusion: The findings provide further support for the view that the investigation of pre-intervention variables can provide useful information in enhancing the predictive accuracy of the success of major life interventions in medical and other settings.
{"title":"The Relationship of Pre-Operative Stress Level to Sustained Outcome in Gastric Bypass Surgery","authors":"R. Lanyon, B. Maxwell","doi":"10.4172/2165-7904.1000269","DOIUrl":"https://doi.org/10.4172/2165-7904.1000269","url":null,"abstract":"Purpose: Previous research has shown that pre-operative health status can serve as a moderator in enhancing the accuracy of certain variables for predicting sustained weight loss after gastric bypass surgery. The present study investigated the role of pre-operative stress level as a moderator in identifying useful pre-operative predictors of sustained weight loss. \u0000Materials and Methods: Follow-up data at a mean of 3.2 years post-operatively were available for 111 patients who had undergone pre-operative assessment on 227 variables including four psychological assessment instruments. These measures were studied for their success in predicting sustained weight loss separately for patients who were under low and high pre-operative stress. \u0000Results: As anticipated, several types of variables (support, coping skills, good adjustment, and good cognitive functioning) predicted success for both groups. In addition, for low-stress patients, social drinking and self-efficacy variables (strong expectations of a broad range of positive changes), and a broader range of personal support variables were the best predictors. For high-stress patients, the best predictors included the presence of a troubled intimate relationship, lack of attention to personal health matters, an active history of smoking, and the possible need for psychiatric medication. Overall, the results show some consistency with the basic postulates of selfdetermination theory. \u0000Conclusion: The findings provide further support for the view that the investigation of pre-intervention variables can provide useful information in enhancing the predictive accuracy of the success of major life interventions in medical and other settings.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122408723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-31DOI: 10.4172/2165-7904.1000272
M. Modolin, W. Cintra, R. I. Rocha, J. Faintuch, C. Camargo, R. Gemperli
Background: Aiming to analyze whether abdominoplasty might benefit quality of life of postbariatric females with redundant abdominal skin folds beyond the first year, a clinical investigation after 2-4 years was designed. Despite being a reputed and popular procedure after massive weight loss, results are still debated. It was hypothesized that sustained improvements in quality of life, independent of previous anti-obesity gastroplasty, would be demonstrated. Methods: This was a prospective study in a female cohort. Patients (N=22) were submitted to abdominoplasty with the age of 42.7 ± 9.1 years and body mass index/BMI of 27.2 ± 2.7 kg/m2, about five years after bariatric Rouxen- Y gastric bypass. The interview occurred after an additional 32.0 ± 8.2 months. Results: All post abdominoplasty indices of quality of life were benefitted, with emphasis on body contour, sexual activity and dressing. Despite frequent surgical wound complications (40.9%), most were minor and patients had few complaints about their scars. More than 90% would undergo the operation again, or recommend it to a friend. Major weight loss, or low BMI at the time of abdominoplasty, signaled better sexual and dressing scores. Sexual score was more increased in younger participants. Conclusion: This paper suggest that abdominoplasty in ex-obese patients increased quality of life, related to the following domains body contour, mobility, hygiene, dressing, and sexuality.
{"title":"Quality of Life after Postbariatric Abdominoplasty in Females: Interest of Age, Current Weight and Weight Loss","authors":"M. Modolin, W. Cintra, R. I. Rocha, J. Faintuch, C. Camargo, R. Gemperli","doi":"10.4172/2165-7904.1000272","DOIUrl":"https://doi.org/10.4172/2165-7904.1000272","url":null,"abstract":"Background: Aiming to analyze whether abdominoplasty might benefit quality of life of postbariatric females with redundant abdominal skin folds beyond the first year, a clinical investigation after 2-4 years was designed. Despite being a reputed and popular procedure after massive weight loss, results are still debated. It was hypothesized that sustained improvements in quality of life, independent of previous anti-obesity gastroplasty, would be demonstrated. \u0000Methods: This was a prospective study in a female cohort. Patients (N=22) were submitted to abdominoplasty with the age of 42.7 ± 9.1 years and body mass index/BMI of 27.2 ± 2.7 kg/m2, about five years after bariatric Rouxen- Y gastric bypass. The interview occurred after an additional 32.0 ± 8.2 months. \u0000Results: All post abdominoplasty indices of quality of life were benefitted, with emphasis on body contour, sexual activity and dressing. Despite frequent surgical wound complications (40.9%), most were minor and patients had few complaints about their scars. More than 90% would undergo the operation again, or recommend it to a friend. Major weight loss, or low BMI at the time of abdominoplasty, signaled better sexual and dressing scores. Sexual score was more increased in younger participants. \u0000Conclusion: This paper suggest that abdominoplasty in ex-obese patients increased quality of life, related to the following domains body contour, mobility, hygiene, dressing, and sexuality.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116740129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-31DOI: 10.4172/2165-7904.1000271
J. Wurtman
Weight gain is a well-known side effect of treatment with psychotropic drugs. More than fifty years ago, drugs such as amitriptyline (Elavil) and lithium were known to be associated with substantial increases in weight and despite new generations of psychotropic drugs, this unwelcome side effect has persisted [1-3]. How much weight is gained varies but in general mood stabilizers and antipsychotics drugs cause more substantial weight gain than antidepressants. Two antipsychotics, clozapine (Clozaril) and olanzapine (Zyprexa) are associated with the greatest prevalence of weight gain; up to 31% of patients treated with clozapine and 40% with olanzapine increase their weight during treatment [3]. Some mood stabilizers such as valproate (Depakote) [3] also are associated with a similarly high incidence of weight gain. Mirtazapine (Remeron) and paroxetine (Paxil) are two antidepressants with the greatest weight gain potential among the anti-depressants although except for buproprion (Wellbutrin) weight gain has been reported among all of the other drugs in this category [4].
{"title":"Weight Gain on Psychotropic Drugs: Has the Obesity Community been PayingAttention?","authors":"J. Wurtman","doi":"10.4172/2165-7904.1000271","DOIUrl":"https://doi.org/10.4172/2165-7904.1000271","url":null,"abstract":"Weight gain is a well-known side effect of treatment with psychotropic drugs. More than fifty years ago, drugs such as amitriptyline (Elavil) and lithium were known to be associated with substantial increases in weight and despite new generations of psychotropic drugs, this unwelcome side effect has persisted [1-3]. How much weight is gained varies but in general mood stabilizers and antipsychotics drugs cause more substantial weight gain than antidepressants. Two antipsychotics, clozapine (Clozaril) and olanzapine (Zyprexa) are associated with the greatest prevalence of weight gain; up to 31% of patients treated with clozapine and 40% with olanzapine increase their weight during treatment [3]. Some mood stabilizers such as valproate (Depakote) [3] also are associated with a similarly high incidence of weight gain. Mirtazapine (Remeron) and paroxetine (Paxil) are two antidepressants with the greatest weight gain potential among the anti-depressants although except for buproprion (Wellbutrin) weight gain has been reported among all of the other drugs in this category [4].","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129138599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-31DOI: 10.4172/2165-7904.1000E117
S. Choi
The famous phrase, “You are what you eat”, reminds us of the important impact of food choice on weight management. Eating and drinking based on food choice is a highly frequent human behavior that is affected by many factors [1]. Consumers report “taste” as one of the most influential factors affecting food choice [2,3]. Taste is the nutritional gatekeeper that determines which foods are chosen and which are rejected, and given the critical role of food intake in weight loss therapy, taste preference is an extremely important factor that needs to be considered to achieve long-term weight loss success. However, inattention to taste preference in weight loss therapy is common, possibly because of the complexity of the causal links between taste preference and food intake. Therefore, the factors that link taste preference and obesity are briefly reviewed in this article, but these factors are not independent of each other.
{"title":"Taste Preference Evaluation: The First Step towards a Successful Weight Loss Strategy","authors":"S. Choi","doi":"10.4172/2165-7904.1000E117","DOIUrl":"https://doi.org/10.4172/2165-7904.1000E117","url":null,"abstract":"The famous phrase, “You are what you eat”, reminds us of the important impact of food choice on weight management. Eating and drinking based on food choice is a highly frequent human behavior that is affected by many factors [1]. Consumers report “taste” as one of the most influential factors affecting food choice [2,3]. Taste is the nutritional gatekeeper that determines which foods are chosen and which are rejected, and given the critical role of food intake in weight loss therapy, taste preference is an extremely important factor that needs to be considered to achieve long-term weight loss success. However, inattention to taste preference in weight loss therapy is common, possibly because of the complexity of the causal links between taste preference and food intake. Therefore, the factors that link taste preference and obesity are briefly reviewed in this article, but these factors are not independent of each other.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130960567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-31DOI: 10.4172/2165-7904.S5-007
J. Kiel, C. Coleman, Andrea H. Mitola, J. Langford, Kevin N. Davis, L. Arterburn
Background: Extreme obesity is associated with elevated risks of morbidities and mortality, and the prevalence of this condition has been rising. Lifestyle interventions are the cornerstone of all treatment options, yet relatively few studies have assessed the effectiveness of commercial programs for attaining clinically meaningful weight loss (≥ 5%) in this population. The purpose of this study was to evaluate the effectiveness of the Medifast 5 & 2 & 2 Plan™ administered along with counseling in obese adults, a majority of whom were extremely obese. Methods: We conducted a systematic retrospective chart review of 62 obese clients from 17 Medifast Weight Control Centers® (MWCCs). Weight, body composition and cardiometabolic risk factor data were abstracted through 24 weeks. Data were recorded electronically, and key data points were independently verified. The primary endpoint was change from baseline body weight at 12 weeks, assessed using Wilcoxon signed rank tests. Results: The population consisted of 57% men, and 82% had a body mass index of ≥ 40 kg/m2. Mean body weight among completers was reduced by 12.9±7.1 kg (-8.6%, n=37) at the 12-week primary endpoint and by 19.3 ± 11.4 kg (12.5%, n=17) at 24 weeks (p 80%, and the meal plan was well-tolerated. Conclusions: The 5 & 2 & 2 Plan used at MWCCs was effective for achieving clinically meaningful weight loss and improving cardiometabolic risk factors in a population of extremely obese individuals. This lifestyle program represents a viable first line approach for meeting treatment goals in extremely obese adults. #NCT0215083.
{"title":"The Effectiveness of a Partial Meal Replacement Program in Extremely Obese Individuals: A Systematic Retrospective Chart Review of Medifast Weight Control Centers","authors":"J. Kiel, C. Coleman, Andrea H. Mitola, J. Langford, Kevin N. Davis, L. Arterburn","doi":"10.4172/2165-7904.S5-007","DOIUrl":"https://doi.org/10.4172/2165-7904.S5-007","url":null,"abstract":"Background: Extreme obesity is associated with elevated risks of morbidities and mortality, and the prevalence of this condition has been rising. Lifestyle interventions are the cornerstone of all treatment options, yet relatively few studies have assessed the effectiveness of commercial programs for attaining clinically meaningful weight loss (≥ 5%) in this population. The purpose of this study was to evaluate the effectiveness of the Medifast 5 & 2 & 2 Plan™ administered along with counseling in obese adults, a majority of whom were extremely obese. Methods: We conducted a systematic retrospective chart review of 62 obese clients from 17 Medifast Weight Control Centers® (MWCCs). Weight, body composition and cardiometabolic risk factor data were abstracted through 24 weeks. Data were recorded electronically, and key data points were independently verified. The primary endpoint was change from baseline body weight at 12 weeks, assessed using Wilcoxon signed rank tests. Results: The population consisted of 57% men, and 82% had a body mass index of ≥ 40 kg/m2. Mean body weight among completers was reduced by 12.9±7.1 kg (-8.6%, n=37) at the 12-week primary endpoint and by 19.3 ± 11.4 kg (12.5%, n=17) at 24 weeks (p 80%, and the meal plan was well-tolerated. Conclusions: The 5 & 2 & 2 Plan used at MWCCs was effective for achieving clinically meaningful weight loss and improving cardiometabolic risk factors in a population of extremely obese individuals. This lifestyle program represents a viable first line approach for meeting treatment goals in extremely obese adults. #NCT0215083.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116895720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-30DOI: 10.4172/2165-7904.S5-005
M. Franz
Background: Benefits of moderate weight loss for the prevention of prediabetes and diabetes are well documented; however, the benefits of weight loss interventions in overt type 2 diabetes are controversial. Objective: To summarize the role of weight loss interventions for the prevention of prediabetes and diabetes and to report the association between weight loss interventions in adults with type 2 diabetes resulting in weight loss greater or less than 5% on metabolic outcomes. Results: Weight loss interventions of 5% to 10% decrease risk factors for prediabetes and diabetes. However, in a systematic review and meta-analysis of weight loss interventions in persons with type 2 diabetes, the majority of the weight loss interventions resulted in weight losses less than 5% and had nonsignificant beneficial effects on A1C and other metabolic outcomes. In another systematic review, reduced-energy eating plans implemented by registered dietitian/nutritionists in persons with type 2 diabetes, regardless of weight loss, resulted in improved A1C levels. Conclusion: Nutrition therapy for persons with type 2 diabetes should encourage a reduced-energy healthful eating plan, regular physical activity, education, and continued support as primary treatment strategies.
{"title":"Weight Loss Interventions and Outcomes: Type 2 Diabetes","authors":"M. Franz","doi":"10.4172/2165-7904.S5-005","DOIUrl":"https://doi.org/10.4172/2165-7904.S5-005","url":null,"abstract":"Background: Benefits of moderate weight loss for the prevention of prediabetes and diabetes are well documented; however, the benefits of weight loss interventions in overt type 2 diabetes are controversial. \u0000Objective: To summarize the role of weight loss interventions for the prevention of prediabetes and diabetes and to report the association between weight loss interventions in adults with type 2 diabetes resulting in weight loss greater or less than 5% on metabolic outcomes. \u0000Results: Weight loss interventions of 5% to 10% decrease risk factors for prediabetes and diabetes. However, in a systematic review and meta-analysis of weight loss interventions in persons with type 2 diabetes, the majority of the weight loss interventions resulted in weight losses less than 5% and had nonsignificant beneficial effects on A1C and other metabolic outcomes. In another systematic review, reduced-energy eating plans implemented by registered dietitian/nutritionists in persons with type 2 diabetes, regardless of weight loss, resulted in improved A1C levels. \u0000Conclusion: Nutrition therapy for persons with type 2 diabetes should encourage a reduced-energy healthful eating plan, regular physical activity, education, and continued support as primary treatment strategies.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125804826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-30DOI: 10.4172/2165-7904.S5-001
P. Fassini, Jose Henrique Silvah, C. M. Lima, C. F. Brandão, L. Wichert-Ana, J. Marchini, V. Suen
This paper emphasizes the methodology of data collection of indirect calorimetry, including establishment of steady state conditions and the standards in which the values are presented. It also aims to describe in details the calculations of VO2, VCO2, Resting Energy Expenditure (REE) and Respiratory Quotient (RQ). The trial is registered with ClinicalTrials.gov number NCT02072694.
{"title":"Indirect Calorimetry: From Expired CO2 Production, Inspired O2 Consumptionto Energy Equivalent","authors":"P. Fassini, Jose Henrique Silvah, C. M. Lima, C. F. Brandão, L. Wichert-Ana, J. Marchini, V. Suen","doi":"10.4172/2165-7904.S5-001","DOIUrl":"https://doi.org/10.4172/2165-7904.S5-001","url":null,"abstract":"This paper emphasizes the methodology of data collection of indirect calorimetry, including establishment of steady state conditions and the standards in which the values are presented. It also aims to describe in details the calculations of VO2, VCO2, Resting Energy Expenditure (REE) and Respiratory Quotient (RQ). The trial is registered with ClinicalTrials.gov number NCT02072694.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114222967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-30DOI: 10.4172/2165-7904.S5-006
P. Hanna, Ricardo Mohammed, M. Nijjar, F. Vazquez, M. Connolly, Jamshed Zuberi
Background: The omentum is associated with accelerated wound healing properties. This IRB-approved multisurgeon single-center study is aimed to evaluate whether complications are reduced by omentopexy (OP) to the staple line after a laparoscopic sleeve gastrectomy. Methods: Adults who have undergone a laparoscopic sleeve gastrectomy at St. Joseph’s Regional Medical Center were reviewed. The group which had the OP performed was compared to the group which did not. Controls were matched for concurrent hiatal hernia repair, degree of obesity, and operating surgeon. OP was only performed by a single surgeon (Surgeon A), however several surgeons performed laparoscopic sleeve gastrectomies. Data extracted included demographics, indication, diagnostic investigations, treatments given, perioperative outcomes, findings, response to treatment given and survival. Complications were defined as a definitive leak or abscess seen on CT or upper GI study. Results: A total of 181 patients underwent a laparoscopic sleeve gastrectomy, of which 75 patients (41%) also underwent OP. 18 patients (9.9%) had a concurrent hiatal hernia repair. Complications were found in 5 patients (2.76%). 4 of the 5 patients who had a complication had underwent OP. Complication rates between the group which had OP and the group which did not have OP showed an OR 6.0571, 95% CI 0.6631 to 55.3280, P 0.1105. No complications were observed in patients who had a concurrent hiatal hernia repair. An association was observed between Surgeon A and increased complications in patients who underwent OP (OR 5.0979, 95% CI 0.2676 to 97.1194, P 0.2787) as well as those who did not undergo OP (OR 1.8271, 95% CI 0.0727 to 45.9307, P 0.7141). An association was also seen between complications and patients who are super obese (OR 1.0833, 95% CI 0.1172 to 10.0126, P 0.9438) and severely obese (OR 2.2319, 95% CI 0.3378 to 14.5153, P 0.3603). No association was seen between complications and patients who are morbidly obese (OR 0.4950, 95% CI 0.0807 to 3.0371, P 0.4474). Limitations: Small sample size, limited patient population, complication rates of a single surgeon performing the omentopexies, comorbidities, as well as limitations of retrospective analysis. Conclusion: OP to the staple line is not associated with decreased overall complication rates. Concurrent hiatal hernia repair was not associated with complications. OP performed in patients who are super obese or severely obese had more complications as opposed to morbidly obese patients who had decreased complications. In addition, OP may be associated with decreased complications only in patients who are morbidly obese. In conclusion, one cannot, in good conscience, continue performing omentopexy given the significantly higher complication rate noted.
背景:大网膜与加速伤口愈合有关。这项经irb批准的多外科医生单中心研究旨在评估腹腔镜袖胃切除术后网膜固定术(OP)是否能减少并发症。方法:对在圣约瑟夫地区医疗中心接受腹腔镜袖胃切除术的成人进行回顾性分析。进行手术的组与未进行手术的组进行比较。对照组在同时进行裂孔疝修补、肥胖程度和手术医生方面进行匹配。OP仅由一名外科医生(外科医生a)实施，但多名外科医生实施了腹腔镜袖胃切除术。提取的数据包括人口统计学、指征、诊断调查、给予的治疗、围手术期结果、发现、对给予的治疗的反应和生存率。并发症的定义是在CT或上消化道检查中发现明确的渗漏或脓肿。结果:共有181例患者行腹腔镜袖胃切除术，其中75例患者(41%)同时行op, 18例患者(9.9%)同时行裂孔疝修补术。并发症5例(2.76%)。有并发症的5例患者中有4例进行了手术。手术组与未手术组的并发症发生率比较，OR为6.0571,95% CI为0.6631 ~ 55.3280,P为0.1105。同时行裂孔疝修补术的患者未见并发症。在手术患者(OR 5.0979, 95% CI 0.2676 ~ 97.1194, P 0.2787)和未手术患者(OR 1.8271, 95% CI 0.0727 ~ 45.9307, P 0.7141)中观察到外科医生A与并发症增加之间的关联。并发症与超级肥胖(OR 1.0833, 95% CI 0.1172 ~ 10.0126, P 0.9438)和严重肥胖(OR 2.2319, 95% CI 0.3378 ~ 14.5153, P 0.3603)患者之间也存在关联。并发症与病态肥胖患者之间无关联(OR 0.4950, 95% CI 0.0807 ~ 3.0371, P 0.4474)。局限性:样本量小，患者人数有限，单个外科医生进行网膜切除术的并发症发生率，合并症，以及回顾性分析的局限性。结论:钉线手术与降低总并发症发生率无关。裂孔疝修补术无并发症。与并发症较少的病态肥胖患者相比，超级肥胖或严重肥胖患者的手术并发症更多。此外，OP可能仅与病态肥胖患者的并发症减少有关。总之，考虑到明显较高的并发症发生率，良心上不能继续进行网膜固定术。
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