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Speech-based Diagnosis of Autism Spectrum Condition by Generative Adversarial Network Representations 基于生成对抗网络表征的自闭症谱系障碍语音诊断
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079492
Jun Deng, N. Cummins, Maximilian Schmitt, Kun Qian, F. Ringeval, Björn Schuller
Machine learning paradigms based on child vocalisations show great promise as an objective marker of developmental disorders such as Autism. In conventional detection systems, hand-crafted acoustic features are usually fed into a discriminative classifier (e.g, Support Vector Machines); however it is well known that the accuracy and robustness of such a system is limited by the size of the associated training data. This paper explores, for the first time, the use of feature representations learnt using a deep Generative Adversarial Network (GAN) for classifying children's speech affected by developmental disorders. A comparative evaluation of our proposed system with different acoustic feature sets is performed on the Child Pathological and Emotional Speech database. Key experimental results presented demonstrate that GAN based methods exhibit competitive performance with the conventional paradigms in terms of the unweighted average recall metric.
基于儿童发声的机器学习范式有望作为自闭症等发育障碍的客观标记。在传统的检测系统中,手工制作的声学特征通常被送入判别分类器(例如,支持向量机);然而,众所周知,这种系统的准确性和鲁棒性受到相关训练数据大小的限制。本文首次探讨了使用深度生成对抗网络(GAN)学习的特征表示来对受发育障碍影响的儿童语言进行分类。我们提出的系统与不同的声学特征集在儿童病理和情绪语言数据库上进行了比较评估。关键实验结果表明,基于GAN的方法在未加权平均召回度量方面表现出与传统范式的竞争力。
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引用次数: 38
Classifying Information from Microblogs during Epidemics 疫情期间对微博信息进行分类
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079491
Koustav Rudra, Ashish Sharma, Niloy Ganguly, Muhammad Imran
At the outbreak of an epidemic, affected communities want/need to get aware of disease symptoms, preventive measures, and treatment strategies. On the other hand, health organizations try to get situational updates to assess the severity of the outbreak, known affected cases, and other details. Recent emergence of social media platforms such as Twitter provide convenient ways and fast access to disseminate and consume information to/from a wider audience. Research studies have shown potential of this online information to address information needs of concerned authorities during outbreaks, epidemics, and pandemics. In this work, we target three communities (i) people who are not affected yet and are looking for prevention-related information (ii) people who are affected and looking for treatment-related information, and (iii) health organizations like WHO, who are interested in gaining situational awareness to make timely decisions. We use Twitter data from two recent outbreaks (Ebola and MERS) to built an automatic classification approach using low level lexical features which are useful to categorize tweets into different disease-related categories.
在流行病爆发时,受影响社区希望/需要了解疾病症状、预防措施和治疗战略。另一方面,卫生组织试图获得最新情况,以评估疫情的严重程度、已知的受影响病例和其他细节。最近出现的社交媒体平台,如Twitter,为向更广泛的受众传播和消费信息提供了方便和快速的途径。研究表明,这种在线信息有潜力在疫情暴发、流行和大流行期间满足有关当局的信息需求。在这项工作中,我们针对三个群体(i)尚未受到影响并正在寻找与预防相关信息的人;(ii)受到影响并正在寻找与治疗相关信息的人;(iii)像世卫组织这样的卫生组织,他们有兴趣获得态势感知以及时做出决策。我们使用来自最近两次爆发(埃博拉和中东呼吸综合征)的Twitter数据来构建一个使用低级词汇特征的自动分类方法,该方法有助于将tweet分类为不同的疾病相关类别。
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引用次数: 21
A Low-cost Adaptable and Personalized Remote Patient Monitoring System 一种低成本、适应性强、个性化的远程病人监护系统
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079458
Eva K. Lee, Yuanbo Yu, Robert A. Davis, B. Egan
Remote patient monitoring systems (RMS) have gained increasing popularity in recent years. RMS have great potential to improve medical services by providing more affordable, timely, and accessible care. This paper describes an effective low-cost RMS that is readily deployable. The system targets chronic disease patients and attempts to reduce patient visits to the hospital and healthcare costs. The system is comprised of three modules: (1) an application for data acquisition, processing, and transmission, (2) an adaptable set of "personalized" sensors for measuring vitals and reporting emergency situations, and (3) a secure communication module for remote patient-physician interactions. The users interface with the RMS through an application installed on a mobile device. Using a return of investment (ROI) cost-benefit analysis and a cohort of 2.7 million patients, we estimate that through the implementation of such a system, the patients and the healthcare system would see benefits within one year.
近年来,远程患者监护系统(RMS)越来越受欢迎。RMS通过提供更实惠、更及时和更容易获得的护理,在改善医疗服务方面具有巨大潜力。本文描述了一个有效的、低成本的、易于部署的RMS。该系统以慢性病患者为目标,试图减少患者的医院就诊次数和医疗费用。该系统由三个模块组成:(1)用于数据采集、处理和传输的应用程序;(2)用于测量生命体征和报告紧急情况的适应性“个性化”传感器;(3)用于远程医患互动的安全通信模块。用户通过安装在移动设备上的应用程序与RMS进行交互。通过投资回报(ROI)成本效益分析和对270万患者的队列分析,我们估计通过实施这样的系统,患者和医疗保健系统将在一年内看到效益。
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引用次数: 2
Data Mining and Time-Series Analysis as Two Complementary Approaches to Study Body Temperature in Obesity 数据挖掘与时间序列分析:肥胖症体温研究的两种互补方法
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079504
R. Fossion, Christopher R. Stephens, Karla P. García-Pelagio, Lorena García-Iglesias
Obesity is becoming a pandemic worldwide but the mechanisms that cause obesity are not well understood. One possibility are metabolic differences between lean and obese people, for which body temperature may offer a proxy which is relatively easy to measure. In the present contribution, we present results from two complementary methodological approaches to measure skin temperature as a function of body weight: in the first study temperature at the axilla and anthropometric measures were collected at a single time point in 1,073 male and female employees of all ages of the Universidad Nacional Autónoma de México (UNAM), whereas in the second study a 1-week continuous monitoring was realized of the skin temperature of the non-dominant wrist of 22 male young adults. In spite of the methodological differences, both studies indicate a higher mean temperature of the obese with respect to the lean subjects, possibly reflecting how obese people offset excess calorie intake by a higher heat transfer to the environment. On the other hand, with respect to the variance of the temperature over groups of underweight, normal weight, overweight and obese subjects, the first study that was realized in controlled circumstances did not detect any differences between groups, whereas the differences that were detected in the second study probably indicate behavioural differences between groups such as the level of physical activity.
肥胖正在成为一种世界性的流行病,但导致肥胖的机制还没有得到很好的理解。一种可能是瘦人和肥胖者之间的代谢差异,体温可能是一个相对容易测量的替代指标。在目前的贡献中,我们介绍了两种互补的方法方法来测量皮肤温度作为体重的函数的结果:在第一项研究中,研究人员在一个时间点收集了1073名不同年龄的国立大学Autónoma de msamxico (UNAM)的男女雇员的腋下温度和人体测量数据,而在第二项研究中,对22名年轻男性的非主手腕皮肤温度进行了为期一周的连续监测。尽管研究方法不同,但两项研究都表明,肥胖者的平均体温高于瘦子,这可能反映了肥胖者是如何通过向环境传递更高的热量来抵消多余的卡路里摄入的。另一方面,关于体重过轻、正常体重、超重和肥胖受试者组之间的温度差异,第一项研究是在受控环境下进行的,并没有发现组间的任何差异,而第二项研究中发现的差异可能表明了组间的行为差异,比如身体活动水平。
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引用次数: 9
Screening for Neonatal Jaundice with a Smartphone 用智能手机筛查新生儿黄疸
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079488
Felix Outlaw, J. Meek, L. MacDonald, T. Leung
A method to screen for jaundice in neonates using a digital image of the sclera is proposed. The RGB pixel values from a raw format image are used to derive an estimate for the total serum bilirubin (TSB). A study at UCH Neonatal Unit found a correlation of r=0.71 (p<0.01) between measured TSB and TSB estimated by this method. The advantages of using a smartphone camera as a mobile screening device are discussed.
提出了一种利用巩膜数字图像筛选新生儿黄疸的方法。RGB像素值从原始格式的图像被用来估计总血清胆红素(TSB)。在UCH新生儿病房的一项研究发现,测量的TSB与用这种方法估计的TSB之间的相关性r=0.71 (p<0.01)。讨论了使用智能手机相机作为移动筛选设备的优点。
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引用次数: 8
Development of a Multi-Device Nutrition Logging Prototype Including a Smartscale 包括智能秤在内的多设备营养记录原型的开发
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079486
A. Seiderer, E. André
In this work we present a portable system for nutrition logging that integrates multiple devices and modalities in order to facilitate food and drink tracking. The system consists of a smartphone, a smartwatch and a smartscale that can be combined flexibly by users depending on the current situation and their personal needs. Based on a requirement analysis, we present the rationale behind the design and implementation of our food and drink logger. We also report the preliminary results of an in-situ study we conducted in order to explore the potential benefits and challenges of a multi-device approach to nutrition tracking in daily life settings.
在这项工作中,我们提出了一种便携式营养记录系统,该系统集成了多种设备和模式,以促进食品和饮料的跟踪。该系统由智能手机、智能手表和智能秤组成,用户可以根据当前情况和个人需求灵活组合。在需求分析的基础上,我们提出了设计和实现食品饮料记录器的基本原理。我们还报告了我们进行的一项原位研究的初步结果,该研究旨在探索日常生活中多设备营养跟踪方法的潜在益处和挑战。
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引用次数: 1
FitBit Garden: A Mobile Game Designed to Increase Physical Activity in Children FitBit花园:一款旨在增加儿童体育活动的手机游戏
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079457
Ashish Amresh, Annmarie A Lyles, L. Small, K. Gary
In this paper, we present the design and deployment of a mobile game titled "FitBit Garden" that encourages children to be physically active by representing the activity levels tracked via a FitBit pedometer in a garden ecosystem. The garden flourishes and grows as children and their parents take positive actions in the real world to improve the child's physical activity. These actions are then manifested into the virtual world via the mobile app. The paper presents the design of the intervention, the methods developed to collect and analyze data and the results of the usability study to determine form, function and acceptability of the intervention.
在本文中,我们介绍了一款名为“FitBit花园”的移动游戏的设计和部署,该游戏通过在花园生态系统中通过FitBit计步器跟踪的活动水平来鼓励儿童进行身体活动。当孩子们和他们的父母在现实世界中采取积极的行动来改善孩子的身体活动时,花园就会蓬勃发展。然后,这些动作通过移动应用程序表现在虚拟世界中。本文介绍了干预的设计,收集和分析数据的方法以及可用性研究的结果,以确定干预的形式,功能和可接受性。
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引用次数: 9
Extracting Gene-Disease Relations from Text to Support Biomarker Discovery 从文本中提取基因-疾病关系以支持生物标志物的发现
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079472
Paul Thompson, S. Ananiadou
The biomedical literature constitutes a rich source of evidence to support the discovery of biomarkers. However, locating evidence in huge volumes of text can be difficult, as typical keyword queries cannot account for the meaning and structure of text. Text mining (TM) methods carry out automated semantic analysis of documents, to facilitate structured searching that can more precisely match users' information needs. We describe our TM approach to the detection of sentence-level associations between genes and diseases, as a first step towards developing a sophisticated search system targeted at locating biomarker evidence in the literature. We vary the sophistication of our detection methodology according to sentence complexity, using either co-occurring mentions of genes and diseases, or linguistic patterns obtained using evidence from approximately 1 million biomedical abstracts. We demonstrate that this method can detect associations more successfully than applying a single technique, with an accuracy that compares highly favourably to related efforts. We also show that the identified relations can complement those detected using alternative approaches.
生物医学文献为支持生物标志物的发现提供了丰富的证据。然而,在大量文本中定位证据可能很困难,因为典型的关键字查询无法解释文本的含义和结构。文本挖掘(TM)方法对文档进行自动语义分析,便于结构化搜索,更精确地匹配用户的信息需求。我们描述了我们的TM方法来检测基因和疾病之间的句子级关联,作为开发一个复杂的搜索系统的第一步,目标是在文献中定位生物标志物证据。我们根据句子的复杂程度改变了检测方法的复杂程度,使用基因和疾病的共同出现,或使用从大约100万份生物医学摘要中获得的证据获得的语言模式。我们证明,这种方法可以比应用单一技术更成功地检测关联,其准确性与相关工作相比非常有利。我们还表明,识别的关系可以补充使用替代方法检测到的关系。
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引用次数: 6
(Bio)medical Publications in the Age of Big Data: Yes, They Are Different 大数据时代的(生物)医学出版物:是的,它们是不同的
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079474
A. V. Altena, S. Olabarriaga
In 2011 the term "Big Data" was introduced by Gartner [5], and since then its use in literature has ever increased, also in the (bio)medical research field [1]. Although the term Big Data is widely used, studies show that its meaning is much debated and many different definitions exist [10]. This variety of definitions may lead to different understandings and therefore difficulties in communication. For example, a researcher that is looking for "Big Data" solutions might miss an interesting method that is not tagged as such. In previous work we studied major topics that appear in Big Data literature using a Topic Modelling approach [8]. However, from that study it was not possible to know whether those topics are exclusive to publications self-identified as Big Data (BD), or not. Therefore, here we investigate the research question: What are the differences between topics in BD and non-Big Data (NBD) corpora?
2011年,“大数据”一词由Gartner提出[5],从那时起,它在文献中的使用越来越多,在(生物)医学研究领域也是如此[1]。虽然“大数据”一词被广泛使用,但研究表明,其含义存在很大争议,存在许多不同的定义[10]。这种不同的定义可能会导致不同的理解,从而导致沟通困难。例如,一个正在寻找“大数据”解决方案的研究人员可能会错过一个没有标记的有趣方法。在之前的工作中,我们使用主题建模方法研究了大数据文献中出现的主要主题[8]。然而,从这项研究中,我们无法知道这些主题是否只属于那些自称为大数据(BD)的出版物。因此,我们在此探讨研究问题:大数据语料库与非大数据语料库中的主题有何不同?
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引用次数: 0
Analysis of Soft Data for Mass Provision of Stereoacuity Testing Through a Serious Game for Health 通过健康大游戏大规模提供立体敏锐度测试的软数据分析
Pub Date : 2017-07-02 DOI: 10.1145/3079452.3079496
G. Ushaw, C. Sharp, Jess Hugill, Sheima Rafiq, C. Black, T. Casanova, K. Vancleef, J. Read, G. Morgan
Mass provision of healthcare through a digital medium can be greatly enhanced by the use of serious games. The accessibility and engagement provided by a serious game to the subject can significantly increase participation. The commercial games industry employs numerous techniques to analyse soft data collected from early users of an application to evolve the application itself and improve the experience of playing it. A game for mass stereoacuity testing of young children is used as a case study in this paper, to illustrate how soft feedback can be used to improve the effectiveness of a clinical trial. The key to the approach is identified as rapid incremental evolution of the application and trial protocol in a manner which increases the amount and usefulness of soft data collected, and reacts to issues identified in the soft data in a timely fashion. It is hoped that the approach can be adopted for a wide range of digital applications for mass health provision.
通过数字媒体提供的大规模医疗保健可以通过使用严肃游戏而大大加强。严肃游戏所提供的可访问性和粘性能够显著提高参与者的参与度。商业游戏行业采用多种技术来分析从应用早期用户那里收集到的软数据,从而改进应用本身,改善游戏体验。本文以儿童大规模立体视觉测试游戏为例,说明如何利用软反馈来提高临床试验的有效性。该方法的关键是应用程序和试验协议的快速增量演变,以增加所收集的软数据的数量和有用性,并及时对软数据中发现的问题作出反应。希望这一方法能够广泛应用于大众保健服务的数字应用。
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引用次数: 4
期刊
Proceedings of the 2017 International Conference on Digital Health
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