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2009 3rd International Workshop on Advances in sensors and Interfaces最新文献

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Smart CMOS temperature sensors 智能CMOS温度传感器
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184774
K. Makinwa
Smart sensors are systems in which sensors and dedicated interface electronics are integrated on the same chip, or at least in the same package. Due to the low-level analog output of typical sensors, designing interface electronics that “does no harm,” i.e. does not impair sensor performance, is quite challenging, especially in today's mainstream CMOS technology, whose inherent precision is limited by 1/f noise and component mismatch. However, since most sensors are quite slow compared to transistors, dynamic techniques can often be used to trade speed or bandwidth for higher precision. Examples of such techniques are auto zeroing, chopping, dynamic element matching, switched-capacitor filtering and sigma-delta modulation. This paper describes the use of such dynamic techniques in the design and realization of state-of-the-art smart CMOS temperature sensors.
智能传感器是将传感器和专用接口电子设备集成在同一芯片上或至少集成在同一封装中的系统。由于典型传感器的低水平模拟输出,设计“无害”的接口电子器件,即不损害传感器性能,是相当具有挑战性的,特别是在当今主流CMOS技术中,其固有精度受到1/f噪声和元件不匹配的限制。然而,由于大多数传感器与晶体管相比相当慢,动态技术通常可以用于交换速度或带宽以获得更高的精度。这些技术的例子有自动归零、斩波、动态元件匹配、开关电容滤波和σ - δ调制。本文介绍了这种动态技术在最先进的智能CMOS温度传感器的设计和实现中的应用。
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引用次数: 3
Membrane proteins embedded in supported lipid bilayers employed in field effect electronic devices 膜蛋白嵌入支持脂双分子层用于场效应电子器件
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184799
M. D. Angione, A. Mallardi, G. Romanazzi, G. Suranna, P. Mastrorilli, D. Cafagna, E. De Giglio, G. Palazzo, L. Torsi
A novel bottom-gate top-contact OTFT architecture has been fabricated. In this device, a lipid bilayer structure embedding a photosynthetic membrane protein extracted from Rhodobacter Sphaeroides has been deposited onto the organic semiconductor film (α,ω-dihexylsexythiophene) prior to the evaporation of source and drain gold contacts. The figures of merit of this device were extracted and compared to those obtained for the same OTFT devoid of the biological film. Only slightly lower performances in terms of field-effect mobility (µ) were observed for the lipid bilayer OTFT that exhibits µ=0.007 cm2/Vs. This result constitutes a preliminary important starting point towards the development of novel highly sensitive and selective herbicides sensors.
制作了一种新型的底栅顶接触OTFT结构。在该装置中,从球形红杆菌中提取的光合膜蛋白包埋在有机半导体膜(α,ω-二己基六噻吩)上的脂质双层结构在源、干金触点蒸发之前被沉积在有机半导体膜上。提取了该装置的优点数字,并与没有生物膜的相同OTFT的优点数字进行了比较。脂质双分子层OTFT的场效应迁移率(µ)仅略低,为µ=0.007 cm2/Vs。这一结果为开发新型高灵敏度、高选择性除草剂传感器奠定了基础。
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引用次数: 5
NO2 QCM gas sensor based on electrochemical deposition of PEDOT 基于电化学沉积PEDOT的NO2 QCM气体传感器
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184792
A. Fort, M. Innocenti, M. Foresti, M. Mugnaini, I. Pasquini, L. Pigani, S. Rocchi, V. Vignoli
In this paper the authors describe the development and the characterization of a Quartz Crystal Microbalance (QCM) sensor for NO2 detection with the sensitive layer made of a thin films of poly (3,4-ethylenedioxythiophene) (PEDOT). The PEDOT layer was obtained by electropolymerization on one of the gold electrodes of a 10 MHz AT-cut commercial quartz crystal. The sensor performance in terms of sensitivity and selectivity were assessed exploiting an ad hoc chemical sampling unit, and a low noise conditioning and processing electronic system. This latter consists of an oscillator hosting the piezoelectric resonator, and of a frequency measurement system granting a (short time) relative accuracy of approximately 10−8, which ensures a mass resolution in the order of the ng. The preliminary obtained results show a NO2 resolution and sensitivity of the order of 1 ppm, and 2.6 Hz/ppm, respectively, at 35 °C constant room temperature and in a dry environment, and show that a satisfactory repeatability can be achieved with recovery cycles in N2 at room temperature.
本文介绍了一种以聚(3,4-乙烯二氧噻吩)(PEDOT)薄膜为敏感层的二氧化氮检测用石英晶体微天平(QCM)传感器的研制及其特性。PEDOT层是通过电聚合在10mhz at切割的商用石英晶体的一个金电极上得到的。利用一个特殊的化学采样单元和一个低噪声调节和处理电子系统,评估了传感器在灵敏度和选择性方面的性能。后者由一个承载压电谐振器的振荡器和一个频率测量系统组成,(短时间)相对精度约为10−8,这确保了在ng数量级的质量分辨率。初步结果表明,在35°C室温和干燥环境下,NO2的分辨率和灵敏度分别为1 ppm和2.6 Hz/ppm,并且在室温下N2中进行回收循环可以获得满意的重复性。
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引用次数: 4
Large area hybrid detector technology based on amorphous silicon photosensors 基于非晶硅光传感器的大面积混合探测器技术
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184763
A. Nascetti, G. de Cesare, D. Caputo
A technological approach for the fabrication of large area hybrid detectors is presented. The proposed hybrid detector consists in an array of hydrogenated amorphous silicon photodiodes directly connected to a CMOS readout chip, which is vertically integrated over the sensor array using flip-chip bonding. In particular, the proposed solution relies on a stack of interconnection layers, deposited on top of the photodiode array, to route each individual pixel output to a separate pre-amplifier channel. This avoids the need for a geometrical matching between the sensor array and the chip contact pads. As a consequence, conventiona non-pixelated readout chip can be used and easy-scalable large area detectors can be produced. Furthermore the sensor array and the readout chip can be optimized independently leading to additional advantages as fast readout, implementation of in-pixel signal conditioning and pre-processing and superior noise performances. Experimental results validating all the technological steps involved in the fabrication of the hybrid detector are reported in detail.
提出了一种制造大面积混合探测器的技术方法。所提出的混合探测器由氢化非晶硅光电二极管阵列组成,该阵列直接连接到CMOS读出芯片,该读出芯片通过倒装键合垂直集成在传感器阵列上。特别是,提出的解决方案依赖于堆叠的互连层,沉积在光电二极管阵列的顶部,将每个单独的像素输出路由到一个单独的前置放大器通道。这避免了传感器阵列和芯片接触垫之间几何匹配的需要。因此,可以使用传统的无像素读出芯片,并且可以生产易于扩展的大面积探测器。此外,传感器阵列和读出芯片可以独立优化,从而具有快速读出,实现像素内信号调理和预处理以及优越的噪声性能等额外优势。实验结果验证了所涉及的所有技术步骤的制造混合探测器的详细报告。
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引用次数: 1
Low-power lock-in amplifier for complex impedance measurement 用于复杂阻抗测量的低功率锁相放大器
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184779
Jiawei Xu, G. Meynants, P. Merken
This paper presents a fully integrated lock-in amplifier intended for nanowire gas sensing. The nanowire will change its conductivity according to the concentration of an absorbing gas. To ensure accurate nanowire impedance measurement, the lock-in technique is implemented to attenuate the low frequency noise and offset by synchronous demodulation or phase-sensitive detection (PSD). Dual-channel lock-in amplifier also provides both resistive and capacitive information of the nanowire in separate channels. Measurement results of the resistors and capacitors show 2% resolution over 10 KΩ – 40 KΩ resistance and 3% resolution over 0.5 nF–1.8 nF capacitance. Moreover, a palladium nanowire sensor was placed in a sealed chamber filled with 10% hydrogen in nitrogen, a 28.7 KΩ to 32.1 KΩ impedance variation was measured through the lock-in amplifier by slowly decreasing the hydrogen concentration. The chip has been implemented with UMC 0.18µm CMOS technology and occupies an area of 2 mm2. The power consumption of the readout circuit is 2 mW from a 1.8V supply.
本文提出了一种用于纳米线气体传感的全集成锁相放大器。纳米线将根据吸收气体的浓度改变其导电性。为了保证纳米线阻抗测量的准确性,采用了锁相技术,通过同步解调或相敏检测(PSD)来衰减低频噪声和偏移。双通道锁相放大器还在单独通道中提供纳米线的电阻和电容信息。电阻和电容的测量结果显示,在10 KΩ - 40 KΩ电阻上分辨率为2%,在0.5 nF - 1.8 nF电容上分辨率为3%。此外,将钯纳米线传感器放置在充满10%氢气的密闭腔室中,通过锁相放大器缓慢降低氢气浓度,测量了28.7 KΩ ~ 32.1 KΩ的阻抗变化。该芯片采用UMC 0.18µm CMOS技术实现,占地面积为2 mm2。从1.8V电源读出电路的功耗为2 mW。
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引用次数: 26
A nanosensor interface based on delta-sigma Arrays 基于delta-sigma阵列的纳米传感器接口
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184788
M. Crescentini, M. Rossi, M. Bennati, F. Thei, A. Baschirotto, M. Tartagni
An emerging area of biosensors is based on the use of structures provided by recent advances of Nanotechnology such as nanowires, nanotubes and nanopores. Among them, the integration of natural nanopores such as ion channels with electronics is a promising approach to develop rapid, sensitive and reliable biosensors able to detect low concentration of target molecules or DNA sequencing. This paper presents a compact and low-cost system able to readout, process and record current in the pA range, provided by biological or synthetic nanopores. The approach is based on the idea that by processing the outputs of a large amount of single-molecule nanosensors would result in a significant increase of resolution and signal-to-noise ratio. The approach consists of an electronic interface able to detect current-based array of nanosensors, where the management of very large amount of data is critical for the readout process. As working example, we acquired the single molecule signals derived from non-covalent bindings between single a-hemolysin pores, embedded into an artificial lipid bilayer, and β-cyclodextrin molecules. The system embeds the electronic readout with the microfluidic where is placed the nanosensor array. The electronic interface is a 0.5mm2 current amplifier based on an array of ΣΔ converters. Then the high rate data streams are processed and downsampled by a DSP that communicates with a PC via a USB interface for data processing and storage.
生物传感器的一个新兴领域是基于使用纳米技术的最新进展所提供的结构,如纳米线、纳米管和纳米孔。其中,将离子通道等天然纳米孔与电子学相结合是开发快速、灵敏、可靠的生物传感器的一种很有前途的方法,可以检测低浓度的靶分子或进行DNA测序。本文介绍了一种紧凑、低成本的系统,能够读取、处理和记录由生物或合成纳米孔提供的pA范围内的电流。该方法基于这样一种想法:通过处理大量单分子纳米传感器的输出,可以显著提高分辨率和信噪比。该方法由一个能够检测基于电流的纳米传感器阵列的电子接口组成,其中对大量数据的管理对于读出过程至关重要。作为工作示例,我们获得了来自嵌入人工脂质双分子层的单个a-溶血素孔和β-环糊精分子之间的非共价结合的单分子信号。该系统将电子读数嵌入微流体中,其中放置了纳米传感器阵列。电子接口是一个基于ΣΔ转换器阵列的0.5mm2电流放大器。然后由DSP对高速率数据流进行处理和下采样,DSP通过USB接口与PC机通信,进行数据处理和存储。
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引用次数: 10
Advanced laser telemetry for vehicle monitoring and other industrial applications 先进的激光遥测车辆监控和其他工业应用
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184782
F. Docchio, L. Fumagalli, P. Tomassini, M. Zanatta, G. Sansoni
The need to prevent train accidents inside railway tunnels has motivated the national railway Company Ferrovie dello Stato to launch a project aimed at installing a number of train monitoring portals at a suitable distance from the tunnel entrances. The first experimental portal, and a second operative one, have been installed by SIRTI S.p.A., respectively in Rastignano and Formia. Our company, in collaboration with the Laboratory of Optoelectronics of the University of Brescia, have been requested to develop all the multisensor architecture for the dimensional and thermal monitoring of the trains to be installed on the portals. One of the key elements of the portal is the shape acquisition sensor, based on scanning telemetry. In the second portal, based on the experience gathered from the first one, a novel shape acquisition system based on time-of-flight telemeters has been developed. This telemeter has been specifically designed for the high-speed, high-resolution monitoring of trains in railway portals, but can be adapted to a number of industrial and environmental applications.
为了防止铁路隧道内发生火车事故,促使国家铁路公司Ferrovie dello Stato启动了一个项目,目的是在距离隧道入口适当的距离上安装一些火车监测门户。第一个实验入口和第二个操作入口分别由SIRTI S.p.A在拉斯蒂尼亚诺和福尔米亚安装。我们公司与布雷西亚大学光电实验室合作,被要求开发安装在门户上的列车尺寸和热监测的所有多传感器架构。入口的关键要素之一是基于扫描遥测的形状采集传感器。在第二门户中,基于第一个门户收集的经验,开发了一种基于飞行时间遥测的新型形状采集系统。该遥测仪专为铁路门户的高速,高分辨率列车监测而设计,但可以适应许多工业和环境应用。
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引用次数: 1
High-density microelectrode array in CMOS technology applied to acute brain slice recordings and to gene-function studies 高密度微电极阵列CMOS技术应用于急性脑切片记录和基因功能研究
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184758
U. Frey
Microfabrication techniques and, in particular, CMOS technology are very powerful tools to devise bioelectronic and multielectrode microsystems. CMOS-based, fully integrated microelectrode arrays for bidirectional communication (stimulation and recording) with electrogenic cells are presented. These complex microsystems with integrated filter and amplification stages feature a high electrode density (3'150 electrodes per mm2) as well as low noise levels (3–7 µVrms) in the recorded signals and are capable of monitoring relevant electrophysiological responses of cells to electrical stimuli or to pharmacological agents with prospective applications in the fields of neuroscience or pharmascreening. Results from two exemplary applications are shown. In the first one, the system was used to record the electrical activity of cardiomyocytes. To modulate their electrogenic properties lentivirus-derived particles were selected to regulate the bone morphogenetic protein-2 gene expression. This provides a tool for gene-function studies and for the discovery and preclinical evaluation of novel genes with potential therapeutic effects. In the second application acute sagittal cerebellar slices have been used to assess the performance of the device and to demonstrate its potential for application in the field of neuroscience. Subcellular resolution could be demonstrated and spike sorting allowed for analysing the measured action potentials from single neurons.
微加工技术,特别是CMOS技术是设计生物电子和多电极微系统的有力工具。基于cmos,完全集成的微电极阵列双向通信(刺激和记录)与致电细胞提出。这些复杂的微系统具有集成的过滤和放大级,具有高电极密度(3'150电极每平方毫米)以及记录信号中的低噪声水平(3 - 7 μ Vrms),能够监测细胞对电刺激或药物的相关电生理反应,在神经科学或药物筛选领域具有前景应用。给出了两个示例应用的结果。在第一个实验中,该系统被用来记录心肌细胞的电活动。为了调节它们的电致特性,我们选择慢病毒衍生的颗粒来调节骨形态发生蛋白-2基因的表达。这为基因功能研究以及具有潜在治疗作用的新基因的发现和临床前评估提供了工具。在第二个应用中,小脑急性矢状面切片被用来评估该装置的性能,并证明其在神经科学领域的应用潜力。亚细胞分辨率可以证明和尖峰分类允许分析测量的动作电位从单个神经元。
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引用次数: 0
Amorphous silicon balanced photodiode for application in biomolecular analysis 非晶硅平衡光电二极管在生物分子分析中的应用
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184760
D. Caputo, G. de Cesare, A. Nascetti, R. Scipinotti
In this work we present an amorphous silicon/amorphous silicon carbide balanced photodiode structure suitable for differential photocurrent measurements in the ultraviolet (UV) and visible range. The device is a three-terminal structure constituted by two series-connected amorphous silicon p-i-n photodiodes. The structure takes advantage of the differential measurement to reveal very small variations of photocurrent in a large background current signal. Application of the device in detection of biomolecules based on the use of photosensors, can allow the increase of both the dynamic range and the sensitivity of the measurement.
在这项工作中,我们提出了一种非晶硅/非晶碳化硅平衡光电二极管结构,适用于紫外和可见光范围内的差分光电流测量。该器件是由两个非晶硅p-i-n光电二极管串联构成的三端结构。该结构利用差分测量来显示大背景电流信号中光电流的微小变化。该装置应用于生物分子的检测中,基于光电传感器的使用,既可以增加动态范围,又可以提高测量灵敏度。
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引用次数: 0
Current mode charge sensitive amplifying technique providing noise performance independent of the radiation detector capacitance 电流模式电荷敏感放大技术,提供与辐射探测器电容无关的噪声性能
Pub Date : 2009-06-25 DOI: 10.1109/IWASI.2009.5184790
T. Noulis, S. Siskos, G. Sarrabayrouse, L. Bary
Alternative current mode charge sensitive amplifier (CSA) topology and related methodology for use as pre-amplification block in radiation detection read out front end IC systems is proposed. It is based on the use of a suitably configured current conveyor architecture providing advantageous noise performance characteristics in comparison to the traditionally used CSA structures. In the proposed architecture the noise at the output of the CSA is independent of the detector capacitance value, allowing the use of large area detectors without affecting the system noise performance. Theoretical analysis and simulation based results are performed concerning the operation - performance of the proposed topology. Measurement results on a current mode CSA prototype fabricated with a 0.35 µm CMOS process by Austriamicrosystems are provided supporting the theoretical and simulation results and confirming the advantageous performance in relation to the traditional voltage mode structures mainly in terms of the noise performance dependency on the detector capacitance value.
提出了在辐射检测读出前端集成电路系统中用作前置放大模块的交流模式电荷敏感放大器(CSA)拓扑结构和相关方法。它是基于使用适当配置的当前输送机结构,与传统使用的CSA结构相比,提供有利的噪声性能特征。在提出的结构中,CSA输出处的噪声与检测器电容值无关,允许使用大面积检测器而不影响系统噪声性能。对所提出的拓扑结构的运行性能进行了理论分析和仿真。本文给出了奥地利微系统公司采用0.35µm CMOS工艺制作的电流模式CSA原型的测量结果,支持了理论和仿真结果,并证实了相对于传统电压模式结构的优势,主要体现在噪声性能与检测器电容值的依赖关系方面。
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引用次数: 1
期刊
2009 3rd International Workshop on Advances in sensors and Interfaces
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